MFSD12

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1secondary metabolite biosynthetic process (GO:0044550)9.56122213
2positive regulation by organism of defense response of other organism involved in symbiotic interact7.54785892
3modulation by symbiont of host immune response (GO:0052553)7.54785892
4positive regulation by symbiont of host defense response (GO:0052509)7.54785892
5modulation by symbiont of host defense response (GO:0052031)7.54785892
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:007.54785892
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:07.54785892
8cellular response to ATP (GO:0071318)6.36941050
9regulation of interferon-beta biosynthetic process (GO:0045357)6.23469333
10adenosine receptor signaling pathway (GO:0001973)6.07470730
11GDP-mannose metabolic process (GO:0019673)5.48162082
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.42999992
13macrophage activation involved in immune response (GO:0002281)5.37305612
14pigment cell differentiation (GO:0050931)4.85843592
15positive regulation of interleukin-8 biosynthetic process (GO:0045416)4.84981069
16adenine nucleotide transport (GO:0051503)4.81102227
17melanocyte differentiation (GO:0030318)4.77772985
18response to host immune response (GO:0052572)4.68995129
19response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.68995129
20purine ribonucleotide transport (GO:0015868)4.64223077
21positive regulation of protein kinase C signaling (GO:0090037)4.64059387
22glycosphingolipid catabolic process (GO:0046479)4.63300393
23regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.60380908
24positive regulation of interferon-alpha production (GO:0032727)4.59395365
25UV protection (GO:0009650)4.54968408
26neutrophil activation involved in immune response (GO:0002283)4.54113367
27regulation of cholesterol storage (GO:0010885)4.46956809
28low-density lipoprotein particle clearance (GO:0034383)4.30916459
29regulation of interferon-alpha production (GO:0032647)4.29139699
30positive regulation of antigen processing and presentation (GO:0002579)4.26502931
31immunoglobulin mediated immune response (GO:0016064)4.24664937
32response to defenses of other organism involved in symbiotic interaction (GO:0052173)4.21306534
33response to host (GO:0075136)4.21306534
34response to host defenses (GO:0052200)4.21306534
35amino sugar catabolic process (GO:0046348)4.20541503
36oligosaccharide catabolic process (GO:0009313)4.19637369
37response to ATP (GO:0033198)4.13682154
38G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)4.11927202
39glycolipid catabolic process (GO:0019377)4.11852118
40antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.10396824
41antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.10396824
42mannose metabolic process (GO:0006013)3.92324530
43purinergic nucleotide receptor signaling pathway (GO:0035590)3.92075355
44regulation of B cell receptor signaling pathway (GO:0050855)3.88196333
45apoptotic cell clearance (GO:0043277)3.84509292
46microglial cell activation (GO:0001774)3.83975969
47lens fiber cell differentiation (GO:0070306)3.82121144
48purine nucleotide transport (GO:0015865)3.79407267
49negative regulation of cell aging (GO:0090344)3.77776109
50DNA strand renaturation (GO:0000733)3.77749617
51respiratory burst (GO:0045730)3.75494126
52nucleoside transmembrane transport (GO:1901642)3.74546150
53myeloid cell activation involved in immune response (GO:0002275)3.66725437
54cellular response to thyroid hormone stimulus (GO:0097067)3.62866496
55pinocytosis (GO:0006907)3.61567071
56response to peptidoglycan (GO:0032494)3.60944296
57natural killer cell mediated immunity (GO:0002228)3.58393448
58natural killer cell mediated cytotoxicity (GO:0042267)3.58393448
59antigen processing and presentation of endogenous antigen (GO:0019883)3.58137948
60ceramide catabolic process (GO:0046514)3.54903578
61macrophage activation (GO:0042116)3.54047426
62regulation of vitamin D biosynthetic process (GO:0060556)3.52905628
63positive regulation of gamma-delta T cell activation (GO:0046645)3.52179634
64negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.52049984
65negative regulation of cell killing (GO:0031342)3.52049984
66lipoprotein transport (GO:0042953)3.50616259
67rRNA methylation (GO:0031167)3.46383342
68purinergic receptor signaling pathway (GO:0035587)3.45990252
69tyrosine metabolic process (GO:0006570)3.37189879
70positive regulation of B cell differentiation (GO:0045579)3.35562017
71meiotic chromosome segregation (GO:0045132)3.35521223
72G-protein coupled purinergic receptor signaling pathway (GO:0035588)3.35355105
73regulation of antigen processing and presentation (GO:0002577)3.34443668
74sphingolipid catabolic process (GO:0030149)3.33030607
75basement membrane organization (GO:0071711)3.31822521
76phenol-containing compound biosynthetic process (GO:0046189)3.30713743
77epithelial cell differentiation involved in prostate gland development (GO:0060742)3.29906273
78neutrophil mediated immunity (GO:0002446)3.29448293
79membrane lipid catabolic process (GO:0046466)3.26419572
80positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.21597958
81regulation of interleukin-8 biosynthetic process (GO:0045414)3.18691948
82L-alpha-amino acid transmembrane transport (GO:1902475)3.16409334
83positive regulation of interferon-beta production (GO:0032728)3.14673099
84Arp2/3 complex-mediated actin nucleation (GO:0034314)3.14549994
85phagosome maturation (GO:0090382)3.14442269
86histone phosphorylation (GO:0016572)3.12894459
87granulocyte activation (GO:0036230)3.10390066
88positive regulation of odontogenesis (GO:0042482)3.08699719
89positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.07820108
90positive regulation of T cell apoptotic process (GO:0070234)3.07776933
91antigen processing and presentation via MHC class Ib (GO:0002475)3.07195305
92barbed-end actin filament capping (GO:0051016)3.06957093
93sphingosine metabolic process (GO:0006670)3.06465822
94sensory perception of taste (GO:0050909)3.04387277
95positive regulation of mast cell activation (GO:0033005)3.03196232
96B cell mediated immunity (GO:0019724)2.98477647
97N-acetylneuraminate metabolic process (GO:0006054)2.98333905
98fat-soluble vitamin biosynthetic process (GO:0042362)2.97795781
99response to thyroid hormone (GO:0097066)2.97360434
100positive regulation of bone remodeling (GO:0046852)2.95876882
101positive regulation of bone resorption (GO:0045780)2.95876882
102regulation of mast cell degranulation (GO:0043304)2.92994791
103neutrophil activation (GO:0042119)2.92802130
104regulation of early endosome to late endosome transport (GO:2000641)2.92233689
105response to lipoprotein particle (GO:0055094)2.90906824
106regulation of leukocyte degranulation (GO:0043300)2.90031295
107defense response to protozoan (GO:0042832)2.89949396
108negative regulation of tumor necrosis factor production (GO:0032720)2.89764555
109pigment biosynthetic process (GO:0046148)2.89005579
110response to muramyl dipeptide (GO:0032495)2.88795217
111I-kappaB phosphorylation (GO:0007252)2.87709362
112decidualization (GO:0046697)2.87103550
113regulation of protein kinase A signaling (GO:0010738)2.87003637
114regulation of integrin activation (GO:0033623)2.85536166
115negative regulation of phagocytosis (GO:0050765)2.85066508
116negative regulation of erythrocyte differentiation (GO:0045647)2.84698190
117nucleoside transport (GO:0015858)2.84187982
118positive regulation of macrophage cytokine production (GO:0060907)2.84070351
119positive regulation of lymphocyte apoptotic process (GO:0070230)2.83212808
120negative regulation of interleukin-17 production (GO:0032700)2.82792905
121negative regulation of interleukin-6 production (GO:0032715)2.82465973
122adhesion of symbiont to host (GO:0044406)2.82257376
123negative regulation of granulocyte differentiation (GO:0030853)2.81996411
124basic amino acid transport (GO:0015802)2.81844151
125protein carboxylation (GO:0018214)2.80924052
126peptidyl-glutamic acid carboxylation (GO:0017187)2.80924052
127positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.80297195
128endosome to melanosome transport (GO:0035646)2.80256520
129endosome to pigment granule transport (GO:0043485)2.80256520
130hyaluronan catabolic process (GO:0030214)2.80190948
131negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556)2.79140660
132negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.78715934
133regulation of mast cell activation (GO:0033003)2.76095098
134regulation of phagocytosis (GO:0050764)2.75691871
135ganglioside metabolic process (GO:0001573)2.75581976
136regulation of protein sumoylation (GO:0033233)2.73971850
137regulation of mast cell activation involved in immune response (GO:0033006)2.73251094
138negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.72613095
139regulation of skeletal muscle contraction (GO:0014819)2.72156554
140regulation of mononuclear cell migration (GO:0071675)2.70753829
141intracellular pH reduction (GO:0051452)2.70013521
142positive regulation of heat generation (GO:0031652)2.69861433
143rRNA modification (GO:0000154)2.69595427
144osteoclast differentiation (GO:0030316)2.69275349
145regulation of macrophage cytokine production (GO:0010935)2.68014161
146modulation by symbiont of host cellular process (GO:0044068)2.67474555
147sialylation (GO:0097503)2.67208865
148positive regulation of leukocyte degranulation (GO:0043302)2.67103061
149diol metabolic process (GO:0034311)2.65797906
150lipopolysaccharide-mediated signaling pathway (GO:0031663)2.65714816
151positive regulation of phagocytosis (GO:0050766)2.65640209
152interaction with host (GO:0051701)2.65315549
153pentose-phosphate shunt (GO:0006098)2.65252355
154nucleotide transmembrane transport (GO:1901679)2.64993571
155regulation of vitamin metabolic process (GO:0030656)2.64889221
156phosphatidylglycerol biosynthetic process (GO:0006655)2.64250551
157neuroepithelial cell differentiation (GO:0060563)2.61901302
158positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.61339354
159lymphocyte mediated immunity (GO:0002449)2.59659655
160leukocyte mediated cytotoxicity (GO:0001909)2.58415952
161semaphorin-plexin signaling pathway (GO:0071526)2.58251259
162negative regulation of mast cell activation (GO:0033004)2.58210431
163positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.57974614
164negative regulation of lipid storage (GO:0010888)2.57741425
165secondary metabolic process (GO:0019748)2.55200502
166cytokine production involved in immune response (GO:0002367)2.54674146
167response to interferon-alpha (GO:0035455)2.54010751
168negative regulation of interleukin-12 production (GO:0032695)2.53225694
169protein localization to endosome (GO:0036010)2.52284306
170keratan sulfate catabolic process (GO:0042340)2.52210578
171positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.51087775
172keratan sulfate metabolic process (GO:0042339)2.49953928
173modulation by virus of host process (GO:0019054)2.48978864
174regulation of type I interferon-mediated signaling pathway (GO:0060338)2.45523544
175very-low-density lipoprotein particle assembly (GO:0034379)2.44096792
176endocytic recycling (GO:0032456)2.43364488
177regulation of monocyte differentiation (GO:0045655)2.41937033
178adhesion of symbiont to host cell (GO:0044650)2.36549267
179virion attachment to host cell (GO:0019062)2.36549267
180negative regulation of macroautophagy (GO:0016242)2.35496445
181regulated secretory pathway (GO:0045055)2.35064365
182protein retention in ER lumen (GO:0006621)2.34281529
183melanin biosynthetic process (GO:0042438)11.9317400
184melanin metabolic process (GO:0006582)10.9056953

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse5.07531172
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.45813524
3IRF8_27001747_Chip-Seq_BMDM_Mouse3.68323408
4SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.67542208
5Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.33932142
6NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.32385097
7BP1_19119308_ChIP-ChIP_Hs578T_Human3.28602409
8* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.95938607
9MYB_21317192_ChIP-Seq_ERMYB_Mouse2.93421536
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.88064326
11VDR_21846776_ChIP-Seq_THP-1_Human2.79677409
12NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.75160726
13RARG_19884340_ChIP-ChIP_MEFs_Mouse2.72473601
14NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.65372366
15BRD4_27068464_Chip-Seq_AML-cells_Mouse2.56443225
16EGR1_19374776_ChIP-ChIP_THP-1_Human2.28931882
17P68_20966046_ChIP-Seq_HELA_Human2.28107751
18SPI1_23127762_ChIP-Seq_K562_Human2.24351664
19SCL_19346495_ChIP-Seq_HPC-7_Human2.18630678
20MYC_22102868_ChIP-Seq_BL_Human2.15479269
21VDR_24763502_ChIP-Seq_THP-1_Human2.15099150
22PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.14878172
23THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.06243911
24TCF7_22412390_ChIP-Seq_EML_Mouse2.02899722
25IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.99976717
26RUNX1_22412390_ChIP-Seq_EML_Mouse1.99640022
27KDM2B_26808549_Chip-Seq_SUP-B15_Human1.96417892
28DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.94629224
29SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.94470700
30RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.94425556
31EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.93962989
32IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.91497612
33ELK3_25401928_ChIP-Seq_HUVEC_Human1.83880007
34LXR_22292898_ChIP-Seq_THP-1_Human1.83076000
35SPI1_23547873_ChIP-Seq_NB4_Human1.82769947
36E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.82222715
37KDM2B_26808549_Chip-Seq_DND41_Human1.80049740
38ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.79659795
39KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.77788677
40ERG_21242973_ChIP-ChIP_JURKAT_Human1.75886405
41MAF_26560356_Chip-Seq_TH1_Human1.73903756
42TET1_21451524_ChIP-Seq_MESCs_Mouse1.72560120
43STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.66553859
44SMC4_20622854_ChIP-Seq_HELA_Human1.66199650
45CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.64334465
46PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.63034888
47CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.62182933
48VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.61198530
49TFEB_21752829_ChIP-Seq_HELA_Human1.59060284
50SA1_27219007_Chip-Seq_ERYTHROID_Human1.58888244
51SRY_22984422_ChIP-ChIP_TESTIS_Rat1.58144806
52PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.56933792
53TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.53975070
54NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.52664958
55CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.51929930
56TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51832574
57KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.51819033
58PU_27001747_Chip-Seq_BMDM_Mouse1.51489026
59UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.51080606
60SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.49491106
61CTCF_27219007_Chip-Seq_Bcells_Human1.48405937
62ZNF263_19887448_ChIP-Seq_K562_Human1.48031482
63EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.46054969
64GATA1_19941827_ChIP-Seq_MEL_Mouse1.45525269
65MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.45188512
66STAT4_19710469_ChIP-ChIP_TH1__Mouse1.43437466
67ESR2_21235772_ChIP-Seq_MCF-7_Human1.43247890
68E2F1_20622854_ChIP-Seq_HELA_Human1.42024912
69TP63_17297297_ChIP-ChIP_HaCaT_Human1.41413907
70UTX_26944678_Chip-Seq_JUKART_Human1.40932632
71GATA1_22383799_ChIP-Seq_G1ME_Mouse1.40778511
72IKZF1_21737484_ChIP-ChIP_HCT116_Human1.40313361
73RARB_24833708_ChIP-Seq_LIVER_Mouse1.39659623
74PHF8_20622854_ChIP-Seq_HELA_Human1.38941820
75MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.38869382
76GATA1_19941826_ChIP-Seq_K562_Human1.37985472
77TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.37899896
78SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.36978272
79GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.36821935
80RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.36460939
81RARA_24833708_ChIP-Seq_LIVER_Mouse1.34413505
82PU.1_20513432_ChIP-Seq_Bcells_Mouse1.34254389
83PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.33559999
84SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.33356450
85STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.32033991
86VDR_24787735_ChIP-Seq_THP-1_Human1.30087973
87TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.29999894
88XRN2_22483619_ChIP-Seq_HELA_Human1.29703407
89SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29500529
90DNAJC2_21179169_ChIP-ChIP_NT2_Human1.29395000
91CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.26791881
92SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24722973
93MYB_26560356_Chip-Seq_TH2_Human1.24365767
94SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.24176630
95SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.23514164
96GATA1_22025678_ChIP-Seq_K562_Human1.23263938
97CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.22619683
98RXRA_24833708_ChIP-Seq_LIVER_Mouse1.22450580
99UBF1/2_26484160_Chip-Seq_HMECs_Human1.22347404
100BCOR_27268052_Chip-Seq_Bcells_Human1.21783074
101CTCF_21964334_Chip-Seq_Bcells_Human1.19792579
102MYB_26560356_Chip-Seq_TH1_Human1.19575977
103CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.19390943
104E2F7_22180533_ChIP-Seq_HELA_Human1.19367932
105TP53_22127205_ChIP-Seq_IMR90_Human1.18741292
106P300_27058665_Chip-Seq_ZR-75-30cells_Human1.18019463
107RACK7_27058665_Chip-Seq_MCF-7_Human1.17236011
108CREB1_26743006_Chip-Seq_LNCaP_Human1.15549705
109TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.15460981
110MAF_26560356_Chip-Seq_TH2_Human1.15397886
111GATA2_22383799_ChIP-Seq_G1ME_Mouse1.14707931
112CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.13635307
113ETS1_21867929_ChIP-Seq_TH2_Mouse1.13595556
114FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.13481774
115KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.12701905
116PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.12369955
117SA1_27219007_Chip-Seq_Bcells_Human1.12189631
118MITF_21258399_ChIP-Seq_MELANOMA_Human1.11870646
119FOXM1_23109430_ChIP-Seq_U2OS_Human1.11006922
120PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10865269
121SPI1_20517297_ChIP-Seq_HL60_Human1.10437520
122GATA2_21666600_ChIP-Seq_HMVEC_Human1.10314969
123STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09815909
124LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.09132553
125BCL6_27268052_Chip-Seq_Bcells_Human1.07903781
126CTCF_26484167_Chip-Seq_Bcells_Mouse1.07173519
127CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.06862349
128TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05842777
129NCOR1_26117541_ChIP-Seq_K562_Human1.05552336
130FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.05291288
131SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03119141
132RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.02662172
133FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.01661617
134GATA2_19941826_ChIP-Seq_K562_Human1.01192011
135KDM2B_26808549_Chip-Seq_K562_Human1.00815776
136RUNX_20019798_ChIP-Seq_JUKART_Human1.00225307
137ELF1_20517297_ChIP-Seq_JURKAT_Human0.98509664
138KDM2B_26808549_Chip-Seq_JURKAT_Human0.96940390
139PPARA_22158963_ChIP-Seq_LIVER_Mouse0.94305608
140EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.94272741
141CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.93644225
142GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.93119453
143KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.92959845
144GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91691242
145CTCF_27219007_Chip-Seq_ERYTHROID_Human0.91676092
146ATF3_27146783_Chip-Seq_COLON_Human0.90480271

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005171_absent_coat_pigmentation7.96800986
2MP0003136_yellow_coat_color7.35088257
3MP0005058_abnormal_lysosome_morphology5.67987046
4MP0003172_abnormal_lysosome_physiology4.61843641
5MP0005409_darkened_coat_color4.30603166
6MP0004381_abnormal_hair_follicle3.73932744
7MP0002877_abnormal_melanocyte_morpholog3.66139938
8MP0003303_peritoneal_inflammation3.65270162
9MP0000569_abnormal_digit_pigmentation3.64861110
10MP0009840_abnormal_foam_cell3.43549673
11MP0001188_hyperpigmentation2.97498893
12MP0001835_abnormal_antigen_presentation2.90150471
13MP0006082_CNS_inflammation2.90036211
14MP0003191_abnormal_cellular_cholesterol2.88384530
15MP0004510_myositis2.78181335
16MP0000372_irregular_coat_pigmentation2.76714110
17MP0003436_decreased_susceptibility_to2.76213211
18MP0001986_abnormal_taste_sensitivity2.76190209
19MP0005257_abnormal_intraocular_pressure2.75893343
20MP0005423_abnormal_somatic_nervous2.72172765
21MP0002419_abnormal_innate_immunity2.53413617
22MP0000604_amyloidosis2.34388509
23MP0005464_abnormal_platelet_physiology2.15486863
24MP0010307_abnormal_tumor_latency2.13585392
25MP0005174_abnormal_tail_pigmentation2.11624104
26MP0003300_gastrointestinal_ulcer2.00292696
27MP0005075_abnormal_melanosome_morpholog1.99792190
28MP0003690_abnormal_glial_cell1.97650118
29MP0003705_abnormal_hypodermis_morpholog1.96254530
30MP0005000_abnormal_immune_tolerance1.96190379
31MP0002452_abnormal_antigen_presenting1.94784392
32MP0002075_abnormal_coat/hair_pigmentati1.94767182
33MP0002095_abnormal_skin_pigmentation1.93123326
34MP0005025_abnormal_response_to1.91185906
35MP0005408_hypopigmentation1.90128799
36MP0003453_abnormal_keratinocyte_physiol1.84760140
37MP0009278_abnormal_bone_marrow1.81579688
38MP0003656_abnormal_erythrocyte_physiolo1.79468104
39MP0001790_abnormal_immune_system1.77592631
40MP0005387_immune_system_phenotype1.77592631
41MP0005451_abnormal_body_composition1.70554532
42MP0003566_abnormal_cell_adhesion1.66004893
43MP0004858_abnormal_nervous_system1.64086208
44MP0003448_altered_tumor_morphology1.63981848
45MP0002723_abnormal_immune_serum1.63620019
46MP0000685_abnormal_immune_system1.62918559
47MP0001800_abnormal_humoral_immune1.62861991
48MP0003075_altered_response_to1.57002593
49MP0004130_abnormal_muscle_cell1.56975928
50MP0001819_abnormal_immune_cell1.56153254
51MP0004947_skin_inflammation1.55607961
52MP0002420_abnormal_adaptive_immunity1.55046374
53MP0005397_hematopoietic_system_phenotyp1.53330470
54MP0001545_abnormal_hematopoietic_system1.53330470
55MP0001186_pigmentation_phenotype1.51046219
56MP0003183_abnormal_peptide_metabolism1.47626542
57MP0001533_abnormal_skeleton_physiology1.47181880
58MP0009785_altered_susceptibility_to1.45695138
59MP0002405_respiratory_system_inflammati1.44115203
60MP0002148_abnormal_hypersensitivity_rea1.40353119
61MP0005083_abnormal_biliary_tract1.37070231
62MP0005310_abnormal_salivary_gland1.36017898
63MP0002998_abnormal_bone_remodeling1.32230789
64MP0000689_abnormal_spleen_morphology1.30516749
65MP0000465_gastrointestinal_hemorrhage1.30335079
66MP0004185_abnormal_adipocyte_glucose1.24894533
67MP0005076_abnormal_cell_differentiation1.24713425
68MP0008469_abnormal_protein_level1.23763795
69MP0001845_abnormal_inflammatory_respons1.23161314
70MP0000015_abnormal_ear_pigmentation1.21293541
71MP0000716_abnormal_immune_system1.19111840
72MP0005167_abnormal_blood-brain_barrier1.18970334
73MP0000343_altered_response_to1.17162777
74MP0002398_abnormal_bone_marrow1.16551927
75MP0000858_altered_metastatic_potential1.12582888
76MP0002090_abnormal_vision1.12273495
77MP0001958_emphysema1.11401279
78MP0002722_abnormal_immune_system1.09102854
79MP0008438_abnormal_cutaneous_collagen1.06641129
80MP0002429_abnormal_blood_cell1.06008120
81MP0001324_abnormal_eye_pigmentation1.04472157
82MP0005166_decreased_susceptibility_to1.00527110
83MP0001851_eye_inflammation1.00434251
84MP0009333_abnormal_splenocyte_physiolog1.00367164
85MP0005671_abnormal_response_to1.00328348
86MP0000371_diluted_coat_color0.99567734
87MP0002166_altered_tumor_susceptibility0.98579650
88MP0005670_abnormal_white_adipose0.98467258
89MP0003806_abnormal_nucleotide_metabolis0.97379683
90MP0003634_abnormal_glial_cell0.89493283
91MP0010329_abnormal_lipoprotein_level0.88925438
92MP0002254_reproductive_system_inflammat0.88689789
93MP0001756_abnormal_urination0.87814603
94MP0003724_increased_susceptibility_to0.87809846
95MP0003878_abnormal_ear_physiology0.85467017
96MP0005377_hearing/vestibular/ear_phenot0.85467017
97MP0003329_amyloid_beta_deposits0.83397552
98MP0009115_abnormal_fat_cell0.79324520
99MP0003091_abnormal_cell_migration0.78300331
100MP0001849_ear_inflammation0.78116790
101MP0004808_abnormal_hematopoietic_stem0.77279166
102MP0001853_heart_inflammation0.76115230
103MP0010155_abnormal_intestine_physiology0.75412293
104MP0000609_abnormal_liver_physiology0.74941751
105MP0003111_abnormal_nucleus_morphology0.74731254
106MP0008260_abnormal_autophagy0.73198149
107MP0001968_abnormal_touch/_nociception0.73126462
108MP0002396_abnormal_hematopoietic_system0.72863445
109MP0005584_abnormal_enzyme/coenzyme_acti0.72472474
110MP0002089_abnormal_postnatal_growth/wei0.70516898
111MP0000367_abnormal_coat/_hair0.70231267
112MP0005666_abnormal_adipose_tissue0.68836166
113MP0003011_delayed_dark_adaptation0.68623073
114MP0000598_abnormal_liver_morphology0.68551233
115MP0009764_decreased_sensitivity_to0.67215122
116MP0001348_abnormal_lacrimal_gland0.65993255
117MP0002638_abnormal_pupillary_reflex0.64125943
118MP0004019_abnormal_vitamin_homeostasis0.63681310
119MP0009763_increased_sensitivity_to0.63681154
120MP0000003_abnormal_adipose_tissue0.63453112
121MP0005365_abnormal_bile_salt0.63453059
122MP0000490_abnormal_crypts_of0.63354907
123MP0000920_abnormal_myelination0.63122499
124MP0000751_myopathy0.62058798
125MP0001873_stomach_inflammation0.61783230
126MP0001915_intracranial_hemorrhage0.61770026
127MP0002006_tumorigenesis0.61654772
128MP0010386_abnormal_urinary_bladder0.60354734
129MP0005197_abnormal_uvea_morphology0.59250683
130MP0003828_pulmonary_edema0.58638001
131MP0002933_joint_inflammation0.58613897
132MP0008961_abnormal_basal_metabolism0.58075938
133MP0003279_aneurysm0.56276427
134MP0000750_abnormal_muscle_regeneration0.54670203
135MP0000747_muscle_weakness0.54221331
136MP0000358_abnormal_cell_content/0.54076169
137MP0001502_abnormal_circadian_rhythm0.53913111
138MP0002139_abnormal_hepatobiliary_system0.53234930
139MP0004233_abnormal_muscle_weight0.53210910
140MP0010234_abnormal_vibrissa_follicle0.50911821
141MP0004043_abnormal_pH_regulation0.42113528
142MP0000538_abnormal_urinary_bladder0.41761624

Predicted human phenotypes

RankGene SetZ-score
1Increased cerebral lipofuscin (HP:0011813)7.70103493
2Vacuolated lymphocytes (HP:0001922)5.87456124
3Increased neuronal autofluorescent lipopigment (HP:0002074)5.86383945
4Abnormality of liposaccharide metabolism (HP:0010968)5.40892160
5Abnormality of glycosphingolipid metabolism (HP:0004343)5.40892160
6Abnormality of glycolipid metabolism (HP:0010969)5.40892160
7Recurrent abscess formation (HP:0002722)5.27443740
8Ocular albinism (HP:0001107)5.25435502
9Dysostosis multiplex (HP:0000943)4.92178384
10Thin bony cortex (HP:0002753)4.90004462
11White forelock (HP:0002211)4.79971172
12Recurrent bacterial skin infections (HP:0005406)4.49207982
13Loss of speech (HP:0002371)4.46316318
14Ulnar bowing (HP:0003031)4.34526153
15Eczematoid dermatitis (HP:0000976)4.34180464
16Recurrent gram-negative bacterial infections (HP:0005420)4.30754663
17Iris hypopigmentation (HP:0007730)4.30333354
18Abnormality of macrophages (HP:0004311)4.27156058
19Urinary glycosaminoglycan excretion (HP:0003541)4.22479814
20Mucopolysacchariduria (HP:0008155)4.22479814
21Annular pancreas (HP:0001734)4.20122525
22Axonal loss (HP:0003447)4.19471006
23Patchy hypopigmentation of hair (HP:0011365)4.10495023
24Disinhibition (HP:0000734)4.09460925
25Abnormality of mucopolysaccharide metabolism (HP:0011020)4.08361245
26Abnormality of polysaccharide metabolism (HP:0011012)4.08361245
27Abnormality of glycosaminoglycan metabolism (HP:0004371)4.08361245
28Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.69883289
29Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.63819692
30Global brain atrophy (HP:0002283)3.61459149
31Turricephaly (HP:0000262)3.59644429
32Premature graying of hair (HP:0002216)3.48904031
33Testicular atrophy (HP:0000029)3.46748052
34Rib fusion (HP:0000902)3.42710988
35Hypoplasia of the fovea (HP:0007750)3.36963127
36Aplasia/Hypoplasia of the fovea (HP:0008060)3.36963127
37Systemic lupus erythematosus (HP:0002725)3.31028014
38Upper motor neuron abnormality (HP:0002127)3.27085642
39Poikiloderma (HP:0001029)3.20754950
40Vaginal fistula (HP:0004320)3.15261269
41Neuronal loss in central nervous system (HP:0002529)3.13042728
42J-shaped sella turcica (HP:0002680)3.12052085
43Autoimmune thrombocytopenia (HP:0001973)3.08546271
44Rectovaginal fistula (HP:0000143)3.03755079
45Rectal fistula (HP:0100590)3.03755079
46Intestinal fistula (HP:0100819)3.02865205
47Myocardial infarction (HP:0001658)3.00688051
48Supranuclear gaze palsy (HP:0000605)3.00408697
49Gingivitis (HP:0000230)3.00013832
50Agnosia (HP:0010524)2.91719260
51Asymmetric septal hypertrophy (HP:0001670)2.90519268
52Joint stiffness (HP:0001387)2.90504542
53Akinesia (HP:0002304)2.86742371
54Aplasia/Hypoplasia of the macula (HP:0008059)2.84792477
55Nuclear cataract (HP:0100018)2.81259284
56Delayed epiphyseal ossification (HP:0002663)2.76964213
57Blue irides (HP:0000635)2.74362166
58Facial hemangioma (HP:0000329)2.70416431
59Diminished motivation (HP:0000745)2.69755245
60Apathy (HP:0000741)2.69247145
61Recurrent skin infections (HP:0001581)2.68736543
62Hepatosplenomegaly (HP:0001433)2.66951608
63Vertebral compression fractures (HP:0002953)2.63227736
64Abnormality of the costochondral junction (HP:0000919)2.63206061
65Aplasia/Hypoplasia affecting the retina (HP:0008061)2.61899060
66Abnormality of the vasculature of the conjunctiva (HP:0008054)2.59845745
67Thoracic kyphosis (HP:0002942)2.59486821
68Male infertility (HP:0003251)2.58243250
69Neoplasm of head and neck (HP:0012288)2.57800109
70Esophageal neoplasm (HP:0100751)2.57800109
71Increased CSF protein (HP:0002922)2.56017729
72Abnormality of the fovea (HP:0000493)2.55236206
73Peripheral demyelination (HP:0011096)2.55086315
74Mediastinal lymphadenopathy (HP:0100721)2.53239280
75Chronic obstructive pulmonary disease (HP:0006510)2.51604667
76Obstructive lung disease (HP:0006536)2.51604667
77Personality changes (HP:0000751)2.50533740
78Pathologic fracture (HP:0002756)2.48531433
79Flat occiput (HP:0005469)2.44806544
80Chronic otitis media (HP:0000389)2.43375931
81Conjunctival telangiectasia (HP:0000524)2.43101782
82Mutism (HP:0002300)2.42927193
83Recurrent fungal infections (HP:0002841)2.42476367
84Cellulitis (HP:0100658)2.42268827
85Nasal polyposis (HP:0100582)2.40793130
86Hypopigmentation of the fundus (HP:0007894)2.36469779
87Retinal atrophy (HP:0001105)2.36340935
88Myositis (HP:0100614)2.35244307
89Interstitial pulmonary disease (HP:0006530)2.35101713
90Inappropriate behavior (HP:0000719)2.34750184
91Enlarged epiphyses (HP:0010580)2.34357578
92Anteriorly placed anus (HP:0001545)2.33727706
93Squamous cell carcinoma (HP:0002860)2.33560164
94Glomerulonephritis (HP:0000099)2.30926079
95Periodontitis (HP:0000704)2.29387806
96Abnormality of the nasal mucosa (HP:0000433)2.27544516
97Popliteal pterygium (HP:0009756)2.25540526
98Coronal craniosynostosis (HP:0004440)2.25179502
99Deformed sella turcica (HP:0002681)2.24743773
100Hemorrhage of the eye (HP:0011885)2.20787732
101Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.20303204
102Short chin (HP:0000331)2.19771195
103Freckling (HP:0001480)2.18669008
104Hypercholesterolemia (HP:0003124)2.18348551
105Abnormality of the intrinsic pathway (HP:0010989)2.18249112
106Abnormality of the thoracic spine (HP:0100711)2.17887690
107Metaphyseal irregularity (HP:0003025)2.17536889
108Bowing of the arm (HP:0006488)2.15713310
109Bowed forearm bones (HP:0003956)2.15713310
110Zonular cataract (HP:0010920)2.15598465
111Elevated erythrocyte sedimentation rate (HP:0003565)2.14417933
112Hematochezia (HP:0002573)2.12706592
113Cerebral aneurysm (HP:0004944)2.12498426
114Neurodegeneration (HP:0002180)2.11398320
115Impaired platelet aggregation (HP:0003540)2.11110908
116Abnormal platelet function (HP:0011869)2.11110908
117Abnormality of the lumbar spine (HP:0100712)2.10901077
118Abnormality of the periventricular white matter (HP:0002518)2.10455074
119Dyschromatopsia (HP:0007641)2.10125188
120Pustule (HP:0200039)2.09586373
121Congenital stationary night blindness (HP:0007642)2.06655795
122Osteomyelitis (HP:0002754)2.06628473
123Hand muscle atrophy (HP:0009130)2.05641199
124Colitis (HP:0002583)2.01552650
125Frequent falls (HP:0002359)2.01451008
126Albinism (HP:0001022)2.01404140
127Spastic tetraparesis (HP:0001285)1.97031359
128Orchitis (HP:0100796)1.96318462
129Bone pain (HP:0002653)1.95852407
130Neurofibrillary tangles (HP:0002185)1.95349804
131Urticaria (HP:0001025)1.95268346
132Recurrent viral infections (HP:0004429)1.94621118
133Poor head control (HP:0002421)1.93971651
134Basal ganglia calcification (HP:0002135)1.92559216
135Heterochromia iridis (HP:0001100)1.91774089
136Upper limb amyotrophy (HP:0009129)1.91481784
137Distal upper limb amyotrophy (HP:0007149)1.91481784
138Reticulocytosis (HP:0001923)1.91368713
139Cerebral inclusion bodies (HP:0100314)1.90419048
140Aplasia of the musculature (HP:0100854)1.89420974
141Osteolytic defects of the phalanges of the hand (HP:0009771)1.89130281
142Osteolytic defects of the hand bones (HP:0009699)1.89130281
143Protuberant abdomen (HP:0001538)1.88727069
144Widely patent fontanelles and sutures (HP:0004492)1.88506544
145Increased serum ferritin (HP:0003281)1.88256747
146Bulbar palsy (HP:0001283)1.87710945
147Attenuation of retinal blood vessels (HP:0007843)1.87055141
148Tetraparesis (HP:0002273)1.86909469
149Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.86247626
150Hyperacusis (HP:0010780)1.83120875
151Fetal akinesia sequence (HP:0001989)1.82681628
152Abnormal trabecular bone morphology (HP:0100671)1.82327932
153Prolonged bleeding time (HP:0003010)1.80520107
154Petechiae (HP:0000967)1.77683558
155Premature loss of primary teeth (HP:0006323)1.77351415
156Progressive visual loss (HP:0000529)1.77216530
157Purpura (HP:0000979)1.75909927
158Nephritis (HP:0000123)1.75156380
159Gastrointestinal inflammation (HP:0004386)1.72908708
160Inflammation of the large intestine (HP:0002037)1.72781942
161Hypophosphatemia (HP:0002148)1.72583503
162Supernumerary nipples (HP:0002558)1.72211792
163Dementia (HP:0000726)1.71943958
164Peripheral hypomyelination (HP:0007182)1.69972872
165Choanal stenosis (HP:0000452)1.69684721
166Cheilitis (HP:0100825)1.67487614

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.95496706
2MAPK153.60794779
3ERN13.48667927
4RIPK43.39751445
5KIT3.31821871
6PKN23.02164979
7TESK22.76945924
8SCYL22.57244633
9MAP4K12.47171464
10TBK12.43328895
11CAMK1D2.42236757
12PDK22.38544482
13BLK2.37955581
14TYK22.33493784
15PRPF4B2.23020976
16MAP3K32.06884614
17RIPK11.98042444
18CSF1R1.95115914
19CAMK1G1.86275224
20WNK41.72277813
21FES1.70989337
22TAOK21.63657604
23TGFBR21.61959680
24TTN1.59260161
25NME21.53472618
26CDK121.48945213
27SMG11.46538062
28SIK21.42611747
29FGR1.37654278
30SYK1.37310785
31ICK1.35856238
32CAMKK11.35567486
33IRAK31.35401546
34EEF2K1.35290563
35MAP3K101.34961651
36HCK1.32145943
37MAP3K91.30768557
38PTK61.30404748
39JAK11.30377471
40JAK31.28755385
41TAOK31.27155714
42IRAK21.25455172
43ZAP701.24775035
44MATK1.22086226
45BMX1.20867569
46EPHB11.20209093
47IRAK41.19687269
48CAMKK21.19128358
49JAK21.17424941
50DAPK21.17249234
51PAK41.16199948
52LRRK21.13859776
53PRKD21.10266693
54ARAF1.09040886
55MST1R1.08461394
56IKBKE1.07602520
57DDR21.05227438
58IKBKB1.05078247
59MAP2K31.03053541
60KSR21.03038344
61CSK1.02381034
62CDC42BPA1.02324128
63MAP3K131.01696586
64MAP3K111.01587167
65GRK60.98483081
66NEK20.94859258
67MAPK110.94157646
68ABL20.88973957
69MAPK120.88788663
70PDK10.88185426
71CDK150.87340670
72BTK0.87314445
73ALK0.86914017
74TYRO30.86577106
75LMTK20.85852506
76PDPK10.85813932
77CDK60.84234097
78STK100.81208748
79CDK11A0.81192920
80EGFR0.80152130
81CDK180.79547906
82LCK0.79304553
83MAP3K140.79080971
84ACVR1B0.78005306
85CDK40.77738214
86TESK10.76407960
87DAPK30.72455169
88MAP2K60.72064138
89PIM10.71241142
90LYN0.69412583
91PRKCH0.68639343
92MARK20.66643645
93PAK60.65552751
94CDK140.61336068
95MOS0.59864949
96RPS6KA20.59813561
97PIM20.59558313
98PRKD10.57615248
99PRKD30.57173112
100TLK10.55341975
101RET0.54918490
102DAPK10.54741021
103DYRK1B0.54562443
104ABL10.54010756
105STK40.53853933
106NEK90.52102466
107SIK10.51455062
108RPS6KA40.51086566
109MAPKAPK30.49984839
110MTOR0.49150867
111PDGFRA0.49107130
112RPS6KA60.48807217
113STK160.48551680
114FYN0.47122126
115GSK3A0.46182389
116PRKCD0.45836308
117AKT20.45756298
118RPS6KC10.45039978
119RPS6KL10.45039978
120PTK2B0.44906011
121SIK30.44752477
122FLT30.44340312
123RPS6KA10.43775917
124BRAF0.43665226
125MUSK0.43374204
126TAOK10.42646737
127PDGFRB0.42228016
128PAK20.41347809
129TRPM70.41296545
130NTRK10.40940998
131MAP3K10.39478065
132FGFR30.38760309
133GRK70.38688521
134SRC0.37779199
135MAP3K60.37072211
136MAP3K80.36401406
137CHUK0.35797932
138SGK30.35640351
139MARK30.34556609
140MAP3K20.34410139
141WEE10.34036212
142PAK10.32964952
143FGFR40.32638330
144HIPK20.30889570

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosaminoglycan degradation_Homo sapiens_hsa005314.32376244
2Lysosome_Homo sapiens_hsa041424.15367695
3Other glycan degradation_Homo sapiens_hsa005112.87626962
4Staphylococcus aureus infection_Homo sapiens_hsa051502.58875730
5Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.43482600
6Osteoclast differentiation_Homo sapiens_hsa043802.38916831
7Leishmaniasis_Homo sapiens_hsa051402.36141086
8Tuberculosis_Homo sapiens_hsa051522.25563236
9Phagosome_Homo sapiens_hsa041452.07303921
10B cell receptor signaling pathway_Homo sapiens_hsa046622.05549156
11Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.00483600
12Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.96403522
13Collecting duct acid secretion_Homo sapiens_hsa049661.95344609
14Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.90995951
15Toll-like receptor signaling pathway_Homo sapiens_hsa046201.90772404
16Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.64502538
17Caffeine metabolism_Homo sapiens_hsa002321.64085629
18Pertussis_Homo sapiens_hsa051331.59090937
19Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.58645902
20Antigen processing and presentation_Homo sapiens_hsa046121.55637418
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.48537479
22Bladder cancer_Homo sapiens_hsa052191.44951572
23Rheumatoid arthritis_Homo sapiens_hsa053231.44278516
24Malaria_Homo sapiens_hsa051441.40929773
25Apoptosis_Homo sapiens_hsa042101.38356232
26Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.34708473
27Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.31187940
28Synaptic vesicle cycle_Homo sapiens_hsa047211.29203956
29Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.27818747
30Legionellosis_Homo sapiens_hsa051341.27220177
31Toxoplasmosis_Homo sapiens_hsa051451.26314636
32Chronic myeloid leukemia_Homo sapiens_hsa052201.22877595
33Salmonella infection_Homo sapiens_hsa051321.22120924
34Acute myeloid leukemia_Homo sapiens_hsa052211.19672079
35Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.18115685
36Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.14246392
37Measles_Homo sapiens_hsa051621.13297990
38Influenza A_Homo sapiens_hsa051641.11887902
39Shigellosis_Homo sapiens_hsa051311.09776560
40Carbohydrate digestion and absorption_Homo sapiens_hsa049731.04575130
41Neurotrophin signaling pathway_Homo sapiens_hsa047221.03028350
42NF-kappa B signaling pathway_Homo sapiens_hsa040641.00410393
43Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.99904480
44Endocytosis_Homo sapiens_hsa041440.98074862
45mTOR signaling pathway_Homo sapiens_hsa041500.95808544
46VEGF signaling pathway_Homo sapiens_hsa043700.94498891
47Adipocytokine signaling pathway_Homo sapiens_hsa049200.92209521
48Chemokine signaling pathway_Homo sapiens_hsa040620.89866875
49Prion diseases_Homo sapiens_hsa050200.88953899
50Tyrosine metabolism_Homo sapiens_hsa003500.88333714
51RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.87373730
52HIF-1 signaling pathway_Homo sapiens_hsa040660.87077291
53Type II diabetes mellitus_Homo sapiens_hsa049300.86583674
54Melanogenesis_Homo sapiens_hsa049160.86428768
55Notch signaling pathway_Homo sapiens_hsa043300.85101644
56Pancreatic cancer_Homo sapiens_hsa052120.84103519
57Galactose metabolism_Homo sapiens_hsa000520.82639838
58Hepatitis B_Homo sapiens_hsa051610.81909412
59Non-small cell lung cancer_Homo sapiens_hsa052230.80861482
60Central carbon metabolism in cancer_Homo sapiens_hsa052300.79467749
61Leukocyte transendothelial migration_Homo sapiens_hsa046700.78618530
62Amoebiasis_Homo sapiens_hsa051460.77464483
63Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.77054174
64Glioma_Homo sapiens_hsa052140.75196803
65Platelet activation_Homo sapiens_hsa046110.74709340
66Sphingolipid signaling pathway_Homo sapiens_hsa040710.74378761
67Renin-angiotensin system_Homo sapiens_hsa046140.73760913
68TNF signaling pathway_Homo sapiens_hsa046680.73191965
69Complement and coagulation cascades_Homo sapiens_hsa046100.73148895
70Hepatitis C_Homo sapiens_hsa051600.71419990
71PPAR signaling pathway_Homo sapiens_hsa033200.69737322
72Insulin resistance_Homo sapiens_hsa049310.69679129
73AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.69534223
74Jak-STAT signaling pathway_Homo sapiens_hsa046300.69213331
75Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68677045
76Vibrio cholerae infection_Homo sapiens_hsa051100.68409484
77Phospholipase D signaling pathway_Homo sapiens_hsa040720.66017437
78NOD-like receptor signaling pathway_Homo sapiens_hsa046210.64992500
79Sphingolipid metabolism_Homo sapiens_hsa006000.61797325
80Pentose phosphate pathway_Homo sapiens_hsa000300.61626513
81Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.61281617
82Hematopoietic cell lineage_Homo sapiens_hsa046400.58825186
83Renal cell carcinoma_Homo sapiens_hsa052110.58716116
84Viral carcinogenesis_Homo sapiens_hsa052030.56195624
85Proteoglycans in cancer_Homo sapiens_hsa052050.55410658
86Glycerolipid metabolism_Homo sapiens_hsa005610.54744790
87Regulation of actin cytoskeleton_Homo sapiens_hsa048100.53286224
88Prolactin signaling pathway_Homo sapiens_hsa049170.52681624
89Fructose and mannose metabolism_Homo sapiens_hsa000510.52070273
90Intestinal immune network for IgA production_Homo sapiens_hsa046720.49827384
91Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.49692983
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.49452072
93Herpes simplex infection_Homo sapiens_hsa051680.48973226
94Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.48951325
95Inositol phosphate metabolism_Homo sapiens_hsa005620.47240701
96Insulin signaling pathway_Homo sapiens_hsa049100.47150486
97Sulfur relay system_Homo sapiens_hsa041220.46831358
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46632225
99Viral myocarditis_Homo sapiens_hsa054160.46298761
100Systemic lupus erythematosus_Homo sapiens_hsa053220.45602800
101Phosphatidylinositol signaling system_Homo sapiens_hsa040700.44976032
102Allograft rejection_Homo sapiens_hsa053300.42738984
103Small cell lung cancer_Homo sapiens_hsa052220.40983480
104Pentose and glucuronate interconversions_Homo sapiens_hsa000400.40766968
105Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40551845
106Vitamin digestion and absorption_Homo sapiens_hsa049770.39775050
107ABC transporters_Homo sapiens_hsa020100.39750241
108Lysine degradation_Homo sapiens_hsa003100.39679695
109Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.39539652
110Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.39179376
111Mineral absorption_Homo sapiens_hsa049780.39082329
112Endometrial cancer_Homo sapiens_hsa052130.38503109
113Dorso-ventral axis formation_Homo sapiens_hsa043200.38331525
114Biosynthesis of amino acids_Homo sapiens_hsa012300.38237922
115Fatty acid biosynthesis_Homo sapiens_hsa000610.37926257
116HTLV-I infection_Homo sapiens_hsa051660.35714371
117Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.35180298
118T cell receptor signaling pathway_Homo sapiens_hsa046600.34867099
119Colorectal cancer_Homo sapiens_hsa052100.34852453
120GnRH signaling pathway_Homo sapiens_hsa049120.33407743
121Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.26634298
122Thyroid hormone signaling pathway_Homo sapiens_hsa049190.26624742
123N-Glycan biosynthesis_Homo sapiens_hsa005100.26169463
124Circadian rhythm_Homo sapiens_hsa047100.25987806
125Ovarian steroidogenesis_Homo sapiens_hsa049130.23864675

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