MFSD14B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)5.38127953
2nuclear pore complex assembly (GO:0051292)4.35855639
3detection of other organism (GO:0098543)4.18956746
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.15531143
5response to peptidoglycan (GO:0032494)4.14925549
6protein localization to endosome (GO:0036010)4.12578949
7detection of bacterium (GO:0016045)3.97373923
8neutrophil activation (GO:0042119)3.96827379
9production of molecular mediator involved in inflammatory response (GO:0002532)3.96216563
10granulocyte activation (GO:0036230)3.96168714
11respiratory burst (GO:0045730)3.90892577
12modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.72718803
13positive regulation by organism of defense response of other organism involved in symbiotic interact3.72718803
14modulation by symbiont of host immune response (GO:0052553)3.72718803
15positive regulation by symbiont of host defense response (GO:0052509)3.72718803
16modulation by symbiont of host defense response (GO:0052031)3.72718803
17modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.72718803
18nuclear pore organization (GO:0006999)3.67994378
19sphingoid metabolic process (GO:0046519)3.65998410
20regulation of hypersensitivity (GO:0002883)3.63756502
21leukocyte aggregation (GO:0070486)3.62208685
22hemidesmosome assembly (GO:0031581)3.54192616
23fatty acid elongation (GO:0030497)3.54117795
24sphingosine metabolic process (GO:0006670)3.53223550
25mitotic chromosome condensation (GO:0007076)3.50375603
26superoxide anion generation (GO:0042554)3.43439072
27lipopolysaccharide-mediated signaling pathway (GO:0031663)3.36835594
28immunoglobulin mediated immune response (GO:0016064)3.35635125
29regulation of early endosome to late endosome transport (GO:2000641)3.29746553
30hypotonic response (GO:0006971)3.29719522
31T-helper 1 type immune response (GO:0042088)3.29341440
32pore complex assembly (GO:0046931)3.28799758
33positive regulation of cellular amide metabolic process (GO:0034250)3.28262365
34pinocytosis (GO:0006907)3.22907263
35hydrogen peroxide biosynthetic process (GO:0050665)3.21463979
36detection of external biotic stimulus (GO:0098581)3.19218943
37mitotic sister chromatid cohesion (GO:0007064)3.16657314
38positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.16469911
39COPI coating of Golgi vesicle (GO:0048205)3.15857007
40Golgi transport vesicle coating (GO:0048200)3.15857007
41positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.14836820
42positive regulation of interferon-alpha production (GO:0032727)3.10974522
43establishment of skin barrier (GO:0061436)3.06775421
44regulation of interferon-beta biosynthetic process (GO:0045357)3.04337244
45reactive oxygen species biosynthetic process (GO:1903409)3.03769603
46diol metabolic process (GO:0034311)3.03380172
47desmosome organization (GO:0002934)3.03288506
48leukocyte migration involved in inflammatory response (GO:0002523)3.01217523
49positive regulation of interleukin-17 production (GO:0032740)3.00817814
50cell adhesion mediated by integrin (GO:0033627)3.00618431
51long-chain fatty acid biosynthetic process (GO:0042759)2.98247656
52antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.95771609
53antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.95771609
54regulation of interferon-alpha production (GO:0032647)2.93957446
55eosinophil chemotaxis (GO:0048245)2.93272666
56antigen processing and presentation of endogenous antigen (GO:0019883)2.93117828
57regulation of activation of Janus kinase activity (GO:0010533)2.90120987
58positive regulation of antigen processing and presentation (GO:0002579)2.89167431
59skin morphogenesis (GO:0043589)2.87921578
60regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.87741758
61positive regulation of monocyte chemotaxis (GO:0090026)2.86989620
62regulation of acute inflammatory response to antigenic stimulus (GO:0002864)2.86901479
63low-density lipoprotein particle clearance (GO:0034383)2.84821740
64regulation of water loss via skin (GO:0033561)2.83900689
65lipoxygenase pathway (GO:0019372)2.83443499
66cell-substrate junction assembly (GO:0007044)2.81206657
67neutrophil mediated immunity (GO:0002446)2.80233058
68myeloid cell activation involved in immune response (GO:0002275)2.77979885
69iron ion import (GO:0097286)2.77942345
70positive regulation of Cdc42 GTPase activity (GO:0043089)2.77610308
71positive regulation of mast cell activation (GO:0033005)2.74856412
72regulation of T-helper 1 cell differentiation (GO:0045625)2.74126485
73cellular protein complex localization (GO:0034629)2.72159503
74cellular extravasation (GO:0045123)2.70837116
75response to muramyl dipeptide (GO:0032495)2.69511274
76amyloid precursor protein catabolic process (GO:0042987)2.69147032
77stress fiber assembly (GO:0043149)2.68573556
78detection of molecule of bacterial origin (GO:0032490)2.67564910
79regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.67130996
80eosinophil migration (GO:0072677)2.66866130
81macrophage activation involved in immune response (GO:0002281)2.66465822
82leukotriene metabolic process (GO:0006691)2.66283295
83long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.65599983
84embryonic process involved in female pregnancy (GO:0060136)2.65457440
85epithelial cell differentiation involved in prostate gland development (GO:0060742)2.64979641
86positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.63702326
87membrane raft organization (GO:0031579)2.63514893
88response to fungus (GO:0009620)2.63102871
89regulation of natural killer cell differentiation (GO:0032823)2.62868076
90regulation of interleukin-17 production (GO:0032660)2.61248500
91regulation of antigen processing and presentation (GO:0002577)2.61241262
92regulation of interleukin-8 biosynthetic process (GO:0045414)2.61033871
93positive regulation of mast cell activation involved in immune response (GO:0033008)2.61014963
94positive regulation of mast cell degranulation (GO:0043306)2.61014963
95barbed-end actin filament capping (GO:0051016)2.57558822
96regulation of mast cell degranulation (GO:0043304)2.57557869
97regulation of dendritic cell antigen processing and presentation (GO:0002604)2.57034309
98detection of biotic stimulus (GO:0009595)2.57013998
99positive regulation of toll-like receptor signaling pathway (GO:0034123)2.56835602
100apoptotic cell clearance (GO:0043277)2.56702329
101positive regulation of T-helper 1 type immune response (GO:0002827)2.56453994
102negative regulation of erythrocyte differentiation (GO:0045647)2.55675718
103positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.55524337
104positive regulation of tumor necrosis factor production (GO:0032760)2.54360443
105positive regulation of NF-kappaB import into nucleus (GO:0042346)2.53487394
106positive regulation of alpha-beta T cell proliferation (GO:0046641)2.53293038
107pentose-phosphate shunt (GO:0006098)2.52775816
108regulation of mast cell activation (GO:0033003)2.52657204
109positive regulation of interleukin-10 production (GO:0032733)2.52379025
110regulation of monocyte chemotaxis (GO:0090025)2.51310042
111intracellular pH reduction (GO:0051452)2.50581545
112positive regulation of chemokine biosynthetic process (GO:0045080)2.49179936
113positive regulation of lymphocyte migration (GO:2000403)2.48780576
114negative regulation of protein localization to plasma membrane (GO:1903077)2.47380810
115cyclooxygenase pathway (GO:0019371)2.47219070
116leukocyte mediated cytotoxicity (GO:0001909)2.46050903
117chronic inflammatory response (GO:0002544)2.45959614
118response to host immune response (GO:0052572)2.44822816
119response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.44822816
120leukocyte degranulation (GO:0043299)2.44784354
121cytokine secretion (GO:0050663)2.43775448
122positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.43126339
123negative regulation of interleukin-17 production (GO:0032700)2.42546135
124positive regulation of interleukin-6 production (GO:0032755)2.41994167
125CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.41912426
126T-helper cell differentiation (GO:0042093)2.41912426
127regulation of growth of symbiont in host (GO:0044126)2.41774163
128negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.41774163
129response to laminar fluid shear stress (GO:0034616)2.41131687
130mammary gland epithelial cell proliferation (GO:0033598)2.39529897
131activation of Rac GTPase activity (GO:0032863)2.38347695
132NADPH regeneration (GO:0006740)2.36332664
133maternal placenta development (GO:0001893)2.36325258
134positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.36216367
135positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.36212583
136cellular response to thyroid hormone stimulus (GO:0097067)2.35759453
137negative regulation of interleukin-12 production (GO:0032695)2.34582733
138dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.33667397
139COPII vesicle coating (GO:0048208)2.33570544
140membrane protein ectodomain proteolysis (GO:0006509)2.32804349
141regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.32286980
142regulation of sister chromatid cohesion (GO:0007063)2.30867472
143DNA unwinding involved in DNA replication (GO:0006268)2.30808559
144protein export from nucleus (GO:0006611)2.28889066
145regulation of leukocyte degranulation (GO:0043300)2.27543830
146regulation of podosome assembly (GO:0071801)2.26421269
147positive regulation of leukocyte degranulation (GO:0043302)2.25827169
148negative regulation of anoikis (GO:2000811)2.24238673
149focal adhesion assembly (GO:0048041)2.23669561
150cell-substrate adherens junction assembly (GO:0007045)2.23669561
151positive regulation of gamma-delta T cell activation (GO:0046645)2.23178598
152regulation of RNA export from nucleus (GO:0046831)2.20815983
153establishment of chromosome localization (GO:0051303)2.20315789
154cellular response to interferon-alpha (GO:0035457)2.20197165
155positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.20175859
156regulation of type I interferon-mediated signaling pathway (GO:0060338)2.19748386
157cortical actin cytoskeleton organization (GO:0030866)2.19296751
158mitotic metaphase plate congression (GO:0007080)2.18506959
159oligosaccharide catabolic process (GO:0009313)2.18283528
160mesodermal cell differentiation (GO:0048333)2.17112511
161endodermal cell differentiation (GO:0035987)2.17051574
162regulation of transforming growth factor beta1 production (GO:0032908)2.15817024
163response to thyroid hormone (GO:0097066)2.15191189
164response to interferon-alpha (GO:0035455)2.14255719
165protein complex localization (GO:0031503)2.13993665
166regulation of nucleobase-containing compound transport (GO:0032239)2.12373594
167maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.11900269
168mitotic sister chromatid segregation (GO:0000070)2.11386202
169sister chromatid segregation (GO:0000819)2.09198797
170response to vitamin D (GO:0033280)2.08806820
171adherens junction assembly (GO:0034333)2.07132729
172surfactant homeostasis (GO:0043129)2.06940275
173negative regulation of fibroblast apoptotic process (GO:2000270)2.06606503
174protein localization to microtubule (GO:0035372)2.06045933
175response to host defenses (GO:0052200)2.05134000

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.52617374
2E2F7_22180533_ChIP-Seq_HELA_Human5.50617156
3IRF8_21731497_ChIP-ChIP_J774_Mouse5.24088698
4IRF8_22096565_ChIP-ChIP_GC-B_Human4.56095700
5TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.21697581
6BP1_19119308_ChIP-ChIP_Hs578T_Human4.18400784
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.62840765
8IRF8_27001747_Chip-Seq_BMDM_Mouse3.27287447
9SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.25432563
10Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.18479004
11FOXM1_23109430_ChIP-Seq_U2OS_Human3.13453962
12MYB_21317192_ChIP-Seq_ERMYB_Mouse3.09361260
13NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.99810624
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.75110271
15IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.74061028
16STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.68946951
17RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.46614600
18IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.44975555
19STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.43239013
20AR_21909140_ChIP-Seq_LNCAP_Human2.36521895
21SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.21086153
22CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.20473713
23NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.11660336
24CLOCK_20551151_ChIP-Seq_293T_Human2.00801545
25KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.91858473
26MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.82486536
27MYC_22102868_ChIP-Seq_BL_Human1.81774030
28STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.80592475
29BRD4_27068464_Chip-Seq_AML-cells_Mouse1.77370731
30SPI1_23547873_ChIP-Seq_NB4_Human1.72071083
31EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.71574495
32STAT4_19710469_ChIP-ChIP_TH1__Mouse1.71566939
33TFEB_21752829_ChIP-Seq_HELA_Human1.63911044
34RUNX_20019798_ChIP-Seq_JUKART_Human1.63616042
35SOX2_20726797_ChIP-Seq_SW620_Human1.63313543
36SMAD_19615063_ChIP-ChIP_OVARY_Human1.62861602
37FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.61604786
38SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.60799930
39KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.60148045
40ZNF263_19887448_ChIP-Seq_K562_Human1.59611727
41TRIM28_21343339_ChIP-Seq_HEK293_Human1.59212011
42SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.56708897
43P63_26484246_Chip-Seq_KERATINOCYTES_Human1.54551182
44ELK3_25401928_ChIP-Seq_HUVEC_Human1.52718782
45NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.51884024
46NRF2_20460467_ChIP-Seq_MEFs_Mouse1.51884024
47GATA1_22025678_ChIP-Seq_K562_Human1.51194792
48SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.50144910
49SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.50144910
50ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.47527398
51PU_27001747_Chip-Seq_BMDM_Mouse1.46452334
52PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.46020957
53KLF4_18555785_ChIP-Seq_MESCs_Mouse1.45577871
54ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.44927922
55MYB_26560356_Chip-Seq_TH2_Human1.42340980
56FOXO3_23340844_ChIP-Seq_DLD1_Human1.42135437
57CDX2_19796622_ChIP-Seq_MESCs_Mouse1.40971648
58E2F4_17652178_ChIP-ChIP_JURKAT_Human1.40714986
59RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.39556648
60NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.37518576
61VDR_21846776_ChIP-Seq_THP-1_Human1.37156859
62ZFX_18555785_ChIP-Seq_MESCs_Mouse1.37098669
63GATA3_26560356_Chip-Seq_TH2_Human1.35428854
64CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.33197871
65VDR_24787735_ChIP-Seq_THP-1_Human1.32347649
66P300_27058665_Chip-Seq_ZR-75-30cells_Human1.31011347
67KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.29724776
68TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.28811872
69KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.27786631
70SALL4_18804426_ChIP-ChIP_XEN_Mouse1.27187141
71EGR1_23403033_ChIP-Seq_LIVER_Mouse1.26916144
72TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.26004162
73TCF7_22412390_ChIP-Seq_EML_Mouse1.23727932
74GATA2_21666600_ChIP-Seq_HMVEC_Human1.23574922
75FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.23327282
76PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.23244293
77TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.22824837
78SCL_19346495_ChIP-Seq_HPC-7_Human1.22585584
79MYCN_18555785_ChIP-Seq_MESCs_Mouse1.21642984
80CJUN_26792858_Chip-Seq_BT549_Human1.21492359
81ATF3_27146783_Chip-Seq_COLON_Human1.20402001
82EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.18938996
83UBF1/2_26484160_Chip-Seq_HMECs_Human1.18532795
84CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.18471328
85NELFA_20434984_ChIP-Seq_ESCs_Mouse1.17020507
86ESR1_21235772_ChIP-Seq_MCF-7_Human1.15468628
87TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.13639024
88MAF_26560356_Chip-Seq_TH1_Human1.13526670
89RARG_19884340_ChIP-ChIP_MEFs_Mouse1.11912962
90CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.11780081
91PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.11537382
92GATA4_25053715_ChIP-Seq_YYC3_Human1.11377993
93E2F1_21310950_ChIP-Seq_MCF-7_Human1.11223470
94RUNX1_22412390_ChIP-Seq_EML_Mouse1.11096402
95ESR2_21235772_ChIP-Seq_MCF-7_Human1.10973771
96SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.10423574
97CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.09884870
98VDR_24763502_ChIP-Seq_THP-1_Human1.09851384
99PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09718191
100GATA3_27048872_Chip-Seq_THYMUS_Human1.09439952
101CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.09052916
102RACK7_27058665_Chip-Seq_MCF-7_Human1.08608891
103HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.07987387
104GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07785740
105CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.07462452
106MYC_18555785_ChIP-Seq_MESCs_Mouse1.06096033
107CHD1_26751641_Chip-Seq_LNCaP_Human1.05656189
108TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.05297076
109NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.04903709
110CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.04577074
111SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.04476593
112EGR1_19374776_ChIP-ChIP_THP-1_Human1.03151794
113BRD4_25478319_ChIP-Seq_HGPS_Human1.03140842
114TP63_23658742_ChIP-Seq_EP156T_Human1.03036864
115GATA1_19941826_ChIP-Seq_K562_Human1.01767972
116TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01612252
117NCOR1_26117541_ChIP-Seq_K562_Human1.01571666
118DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.00566934
119STAT3_1855785_ChIP-Seq_MESCs_Mouse1.00242165
120SOX9_24532713_ChIP-Seq_HFSC_Mouse0.99906379
121NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.98795984
122FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.98754531
123FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.97151563
124KDM2B_26808549_Chip-Seq_SUP-B15_Human0.96849683
125STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.96832691
126GATA2_22383799_ChIP-Seq_G1ME_Mouse0.96569320
127SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.95117796
128ERG_20887958_ChIP-Seq_HPC-7_Mouse0.94695707
129SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.94407296
130PPAR_26484153_Chip-Seq_NCI-H1993_Human0.94224285
131MYB_26560356_Chip-Seq_TH1_Human0.93351412
132CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.92586124
133MYC_19079543_ChIP-ChIP_MESCs_Mouse0.92561029
134MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.92417755
135RXR_22108803_ChIP-Seq_LS180_Human0.91823973
136GATA2_19941826_ChIP-Seq_K562_Human0.90314084
137JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89672155
138PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88491791
139EGR1_19032775_ChIP-ChIP_M12_Human0.86396832
140PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86375690
141POU3F2_20337985_ChIP-ChIP_501MEL_Human0.83701925
142RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.83224434
143JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82669172
144WT1_19549856_ChIP-ChIP_CCG9911_Human0.82206544
145LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.81145939
146FOXA1_25552417_ChIP-Seq_VCAP_Human0.80052254
147LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.79931507
148SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.79119348
149SPI1_23127762_ChIP-Seq_K562_Human0.78526360
150ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.77793787
151VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.77578238
152FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.76354723
153CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.76104242
154ELK1_19687146_ChIP-ChIP_HELA_Human0.76032571
155SOX2_27498859_Chip-Seq_STOMACH_Mouse0.74172668

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.62647416
2MP0003436_decreased_susceptibility_to3.22234277
3MP0002148_abnormal_hypersensitivity_rea3.09212286
4MP0001835_abnormal_antigen_presentation3.06274916
5MP0009785_altered_susceptibility_to3.04633625
6MP0003724_increased_susceptibility_to2.98664978
7MP0002419_abnormal_innate_immunity2.82951441
8MP0002796_impaired_skin_barrier2.73297647
9MP0008438_abnormal_cutaneous_collagen2.71318252
10MP0010352_gastrointestinal_tract_polyps2.70784138
11MP0004947_skin_inflammation2.52650915
12MP0005000_abnormal_immune_tolerance2.52373691
13MP0003300_gastrointestinal_ulcer2.42156064
14MP0005025_abnormal_response_to2.39951784
15MP0006082_CNS_inflammation2.38292402
16MP0003303_peritoneal_inflammation2.37674776
17MP0005451_abnormal_body_composition2.28084308
18MP0010234_abnormal_vibrissa_follicle2.27903794
19MP0005058_abnormal_lysosome_morphology2.20418746
20MP0004381_abnormal_hair_follicle2.10552574
21MP0005671_abnormal_response_to2.02527309
22MP0001790_abnormal_immune_system2.02307941
23MP0005387_immune_system_phenotype2.02307941
24MP0002452_abnormal_antigen_presenting2.00918261
25MP0001533_abnormal_skeleton_physiology1.99528037
26MP0003453_abnormal_keratinocyte_physiol1.96910130
27MP0000685_abnormal_immune_system1.92390395
28MP0010678_abnormal_skin_adnexa1.92014924
29MP0002723_abnormal_immune_serum1.91868234
30MP0003191_abnormal_cellular_cholesterol1.90343849
31MP0001800_abnormal_humoral_immune1.82288335
32MP0000383_abnormal_hair_follicle1.81002698
33MP0000920_abnormal_myelination1.80611328
34MP0005501_abnormal_skin_physiology1.79805304
35MP0005076_abnormal_cell_differentiation1.78022536
36MP0008057_abnormal_DNA_replication1.77754748
37MP0001819_abnormal_immune_cell1.76343068
38MP0004782_abnormal_surfactant_physiolog1.75830695
39MP0002420_abnormal_adaptive_immunity1.74675331
40MP0001216_abnormal_epidermal_layer1.72825736
41MP0003091_abnormal_cell_migration1.72111683
42MP0005464_abnormal_platelet_physiology1.71514002
43MP0008260_abnormal_autophagy1.65833453
44MP0001845_abnormal_inflammatory_respons1.60222177
45MP0000465_gastrointestinal_hemorrhage1.58895987
46MP0009764_decreased_sensitivity_to1.58432284
47MP0005275_abnormal_skin_tensile1.53850083
48MP0005257_abnormal_intraocular_pressure1.53612365
49MP0005310_abnormal_salivary_gland1.52308377
50MP0002060_abnormal_skin_morphology1.48575021
51MP0003195_calcinosis1.47897342
52MP0001851_eye_inflammation1.47633829
53MP0002006_tumorigenesis1.47201989
54MP0001853_heart_inflammation1.45521613
55MP0005409_darkened_coat_color1.44936473
56MP0003172_abnormal_lysosome_physiology1.44619536
57MP0006054_spinal_hemorrhage1.44002462
58MP0001849_ear_inflammation1.42348057
59MP0004808_abnormal_hematopoietic_stem1.42125444
60MP0009840_abnormal_foam_cell1.40321539
61MP0004272_abnormal_basement_membrane1.39754478
62MP0004957_abnormal_blastocyst_morpholog1.39415548
63MP0005023_abnormal_wound_healing1.36865805
64MP0002405_respiratory_system_inflammati1.36443974
65MP0003448_altered_tumor_morphology1.33395426
66MP0003111_abnormal_nucleus_morphology1.32028486
67MP0002009_preneoplasia1.31995331
68MP0008469_abnormal_protein_level1.30845836
69MP0003075_altered_response_to1.30520166
70MP0002396_abnormal_hematopoietic_system1.29710089
71MP0001346_abnormal_lacrimal_gland1.29076917
72MP0003690_abnormal_glial_cell1.28399364
73MP0002166_altered_tumor_susceptibility1.27647390
74MP0001545_abnormal_hematopoietic_system1.26284471
75MP0005397_hematopoietic_system_phenotyp1.26284471
76MP0000377_abnormal_hair_follicle1.24217089
77MP0010155_abnormal_intestine_physiology1.22916703
78MP0003941_abnormal_skin_development1.21059082
79MP0004185_abnormal_adipocyte_glucose1.19799453
80MP0003656_abnormal_erythrocyte_physiolo1.19778807
81MP0004264_abnormal_extraembryonic_tissu1.19347313
82MP0001958_emphysema1.18911469
83MP0001191_abnormal_skin_condition1.18405525
84MP0002098_abnormal_vibrissa_morphology1.18080533
85MP0005164_abnormal_response_to1.16993566
86MP0002254_reproductive_system_inflammat1.16551055
87MP0003693_abnormal_embryo_hatching1.15556779
88MP0000604_amyloidosis1.15046813
89MP0010771_integument_phenotype1.14635490
90MP0003950_abnormal_plasma_membrane1.14286137
91MP0001730_embryonic_growth_arrest1.13575201
92MP0000647_abnormal_sebaceous_gland1.12635659
93MP0000716_abnormal_immune_system1.12485521
94MP0009333_abnormal_splenocyte_physiolog1.12089207
95MP0005408_hypopigmentation1.11366145
96MP0005621_abnormal_cell_physiology1.10417609
97MP0010307_abnormal_tumor_latency1.10193225
98MP0002277_abnormal_respiratory_mucosa1.09547084
99MP0000427_abnormal_hair_cycle1.07344727
100MP0009278_abnormal_bone_marrow1.07067183
101MP0000343_altered_response_to1.06507908
102MP0002998_abnormal_bone_remodeling1.04690310
103MP0000015_abnormal_ear_pigmentation1.02811094
104MP0005390_skeleton_phenotype1.01046605
105MP0010094_abnormal_chromosome_stability1.00280918
106MP0003186_abnormal_redox_activity1.00179243
107MP0003763_abnormal_thymus_physiology0.99315075
108MP0003183_abnormal_peptide_metabolism0.99254334
109MP0000350_abnormal_cell_proliferation0.98341514
110MP0001873_stomach_inflammation0.97201299
111MP0004233_abnormal_muscle_weight0.96901986
112MP0003077_abnormal_cell_cycle0.96374388
113MP0008004_abnormal_stomach_pH0.94830050
114MP0002398_abnormal_bone_marrow0.93602722
115MP0005167_abnormal_blood-brain_barrier0.93525513
116MP0000858_altered_metastatic_potential0.93316751
117MP0001915_intracranial_hemorrhage0.92280561
118MP0000490_abnormal_crypts_of0.92246816
119MP0003566_abnormal_cell_adhesion0.90700453
120MP0001243_abnormal_dermal_layer0.90526525
121MP0002877_abnormal_melanocyte_morpholog0.90031005
122MP0002086_abnormal_extraembryonic_tissu0.89664559
123MP0009931_abnormal_skin_appearance0.89032556
124MP0002429_abnormal_blood_cell0.88352190
125MP0003806_abnormal_nucleotide_metabolis0.87124831
126MP0009763_increased_sensitivity_to0.86778061
127MP0003279_aneurysm0.85068370
128MP0000371_diluted_coat_color0.83913884
129MP0003221_abnormal_cardiomyocyte_apopto0.83723000
130MP0004510_myositis0.83030198
131MP0000689_abnormal_spleen_morphology0.81886440
132MP0008007_abnormal_cellular_replicative0.81735038
133MP0005384_cellular_phenotype0.81670756
134MP0003795_abnormal_bone_structure0.80635080
135MP0005623_abnormal_meninges_morphology0.80443148
136MP0002933_joint_inflammation0.80370733
137MP0000767_abnormal_smooth_muscle0.79722785
138MP0002722_abnormal_immune_system0.79388144
139MP0001542_abnormal_bone_strength0.77931415
140MP0000579_abnormal_nail_morphology0.77594734
141MP0003828_pulmonary_edema0.77235787
142MP0000367_abnormal_coat/_hair0.76434781

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)5.91879498
2Recurrent abscess formation (HP:0002722)5.85840205
3Recurrent bacterial skin infections (HP:0005406)5.55601996
4Congenital nonbullous ichthyosiform erythroderma (HP:0007479)4.82530847
5Recurrent gram-negative bacterial infections (HP:0005420)4.36900610
6Abnormality of macrophages (HP:0004311)4.30090998
7Congenital ichthyosiform erythroderma (HP:0007431)4.14170895
8Parakeratosis (HP:0001036)4.08093113
9Vacuolated lymphocytes (HP:0001922)3.82691603
10Recurrent skin infections (HP:0001581)3.51505456
11Thick nail (HP:0001805)3.51062890
12Stomatitis (HP:0010280)3.50148704
13Osteolytic defects of the hand bones (HP:0009699)3.45522186
14Osteolytic defects of the phalanges of the hand (HP:0009771)3.45522186
15Premature rupture of membranes (HP:0001788)3.44628378
16Gingivitis (HP:0000230)3.32783244
17Increased neuronal autofluorescent lipopigment (HP:0002074)3.27830796
18Pustule (HP:0200039)3.27182086
19Increased IgE level (HP:0003212)3.21844596
20Increased cerebral lipofuscin (HP:0011813)3.12797978
21Gangrene (HP:0100758)3.10903396
22Chronic obstructive pulmonary disease (HP:0006510)3.10161834
23Obstructive lung disease (HP:0006536)3.10161834
24Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.07933749
25Increased IgM level (HP:0003496)3.03610598
26Syringomyelia (HP:0003396)3.03097009
27Spinal cord lesions (HP:0100561)3.03097009
28Mediastinal lymphadenopathy (HP:0100721)3.02219897
29Erythema (HP:0010783)2.99233616
30Periodontitis (HP:0000704)2.98666771
31Abnormality of liposaccharide metabolism (HP:0010968)2.94492244
32Abnormality of glycosphingolipid metabolism (HP:0004343)2.94492244
33Abnormality of glycolipid metabolism (HP:0010969)2.94492244
34Myositis (HP:0100614)2.93288026
35Elevated erythrocyte sedimentation rate (HP:0003565)2.91414011
36Ankyloglossia (HP:0010296)2.90419867
37Autoimmune thrombocytopenia (HP:0001973)2.84981864
38Hepatosplenomegaly (HP:0001433)2.82012610
39Hypergammaglobulinemia (HP:0010702)2.81709892
40Erythroderma (HP:0001019)2.81608790
41Urticaria (HP:0001025)2.76567135
42Vasculitis (HP:0002633)2.72033550
43Systemic lupus erythematosus (HP:0002725)2.68982330
44Orchitis (HP:0100796)2.65800760
45Protrusio acetabuli (HP:0003179)2.63634382
46Abnormality of oral frenula (HP:0000190)2.59042414
47Chronic otitis media (HP:0000389)2.58579862
48Segmental peripheral demyelination/remyelination (HP:0003481)2.58378407
49Vertebral compression fractures (HP:0002953)2.56643673
50Recurrent fungal infections (HP:0002841)2.51943440
51Optic neuritis (HP:0100653)2.48455596
52Retrobulbar optic neuritis (HP:0100654)2.48455596
53Atrophic scars (HP:0001075)2.45541621
54Petechiae (HP:0000967)2.44583152
55Ectropion (HP:0000656)2.44238305
56Axonal loss (HP:0003447)2.38467801
57Interstitial pulmonary disease (HP:0006530)2.35622876
58Selective tooth agenesis (HP:0001592)2.33788215
59Subacute progressive viral hepatitis (HP:0006572)2.28213597
60Cerebral aneurysm (HP:0004944)2.27322122
61Dysostosis multiplex (HP:0000943)2.27045673
62Asymmetry of the thorax (HP:0001555)2.26582355
63Autoimmune hemolytic anemia (HP:0001890)2.26482448
64Onycholysis (HP:0001806)2.23819689
65Dilatation of the ascending aorta (HP:0005111)2.21797671
66Palmoplantar hyperkeratosis (HP:0000972)2.21179109
67Arterial tortuosity (HP:0005116)2.19807176
68Fragile skin (HP:0001030)2.19228192
69Short nail (HP:0001799)2.17478201
70Cellulitis (HP:0100658)2.17064002
71Alopecia of scalp (HP:0002293)2.16878343
72Poor head control (HP:0002421)2.15708264
73Recurrent viral infections (HP:0004429)2.12272346
74Plantar hyperkeratosis (HP:0007556)2.11855152
75Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.11171539
76Vascular tortuosity (HP:0004948)2.10442103
77Palmar hyperkeratosis (HP:0010765)2.09755113
78Skin ulcer (HP:0200042)2.09631721
79Deviation of the thumb (HP:0009603)2.08104557
80Gingival bleeding (HP:0000225)2.07791146
81Basal ganglia calcification (HP:0002135)2.07742713
82Abnormality of the distal phalanges of the toes (HP:0010182)2.06823185
83Amyloidosis (HP:0011034)2.04269615
84Mutism (HP:0002300)2.02979629
85Disinhibition (HP:0000734)2.02807486
86Tetraparesis (HP:0002273)2.01002899
87Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.99544017
88Gastrointestinal infarctions (HP:0005244)1.99161531
89Absent frontal sinuses (HP:0002688)1.99007014
90Leukocytosis (HP:0001974)1.97050243
91Anhidrosis (HP:0000970)1.96698601
92Premature loss of primary teeth (HP:0006323)1.96449595
93Glomerulonephritis (HP:0000099)1.96280783
94Neurofibrillary tangles (HP:0002185)1.94751617
95Pruritus (HP:0000989)1.94574240
96Milia (HP:0001056)1.94473075
97Metaphyseal irregularity (HP:0003025)1.94207079
98Progressive visual loss (HP:0000529)1.94073446
99Purpura (HP:0000979)1.91995341
100Myocardial infarction (HP:0001658)1.91566275
101Vertebral arch anomaly (HP:0008438)1.91385836
102Recurrent pneumonia (HP:0006532)1.91267217
103Blepharitis (HP:0000498)1.90458143
104Eosinophilia (HP:0001880)1.90423266
105Abnormality of nail color (HP:0100643)1.90329238
106Follicular hyperkeratosis (HP:0007502)1.90044481
107Flat acetabular roof (HP:0003180)1.88428433
108Pulmonary infiltrates (HP:0002113)1.88132737
109Loss of speech (HP:0002371)1.86180828
110Hypotrichosis (HP:0001006)1.85489871
111Ankle contracture (HP:0006466)1.85083470
112Spondylolisthesis (HP:0003302)1.84253271
113Meningitis (HP:0001287)1.83674291
114Proximal placement of thumb (HP:0009623)1.83628208
115Peritonitis (HP:0002586)1.83424752
116Abnormality of the thoracic spine (HP:0100711)1.82997876
117Pathologic fracture (HP:0002756)1.80045351
118Lip pit (HP:0100267)1.79867597
119Sepsis (HP:0100806)1.79772156
120Increased connective tissue (HP:0009025)1.79296769
121Long palpebral fissure (HP:0000637)1.78135091
122Deep philtrum (HP:0002002)1.77914151
123Corneal erosion (HP:0200020)1.77222655
124Thoracic kyphosis (HP:0002942)1.76965531
125Aortic dissection (HP:0002647)1.75541433
126Blue sclerae (HP:0000592)1.74807843
127Coarse hair (HP:0002208)1.74398573
128Keratoconjunctivitis sicca (HP:0001097)1.74191865
129Peripheral demyelination (HP:0011096)1.72723056
130Stenosis of the external auditory canal (HP:0000402)1.71796374
131Bone pain (HP:0002653)1.71333257
132Thoracolumbar scoliosis (HP:0002944)1.71312026
133Ulnar bowing (HP:0003031)1.71166369
134Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.71037149
135Patchy hypopigmentation of hair (HP:0011365)1.69786655
136Osteomyelitis (HP:0002754)1.69695470
137Aortic aneurysm (HP:0004942)1.69683174
138Abnormality of the lumbar spine (HP:0100712)1.68541109
139Papillary thyroid carcinoma (HP:0002895)1.67554335
140Insidious onset (HP:0003587)1.67114726
141Termporal pattern (HP:0011008)1.67114726
142Progressive neurologic deterioration (HP:0002344)1.66739748
143Entropion (HP:0000621)1.66336597
144Mitral stenosis (HP:0001718)1.65130227
145Paraparesis (HP:0002385)1.64711018
146Wormian bones (HP:0002645)1.63533466
147Viral hepatitis (HP:0006562)1.63416211
148Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.62961300
149Cheilitis (HP:0100825)1.62596863
150Aplasia cutis congenita (HP:0001057)1.62549048
151Natal tooth (HP:0000695)1.62223708
152Keratoconjunctivitis (HP:0001096)1.61956575
153Cutaneous photosensitivity (HP:0000992)1.61902525
154Abnormal foot bone ossification (HP:0010675)1.61096950
155Micronodular cirrhosis (HP:0001413)1.59827197
156Aneurysm (HP:0002617)1.59432595
157Uterine leiomyosarcoma (HP:0002891)1.59240351
158Leiomyosarcoma (HP:0100243)1.59240351
159Relative macrocephaly (HP:0004482)1.58950100
160Right ventricular cardiomyopathy (HP:0011663)1.58619378
161Flared metaphyses (HP:0003015)1.58451830
162Hypokinesia (HP:0002375)1.58249675
163Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.57988066
164Nail dystrophy (HP:0008404)1.57556082
165Fatigue (HP:0012378)1.57278933
166Cervical subluxation (HP:0003308)1.56403726
167Thin bony cortex (HP:0002753)1.56368521
168Abnormal vertebral ossification (HP:0100569)1.53708103

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PBK4.37013439
2MST43.72295213
3MAP3K143.63243430
4MAP3K93.28385846
5RIPK43.19740980
6BLK3.04138177
7PRPF4B2.83887971
8SMG12.81723118
9IRAK42.70037602
10MST1R2.65733579
11EPHB12.43860617
12IRAK32.39979494
13TRPM72.29173192
14TRIB32.08927638
15TAF12.03082840
16MAP3K132.00360405
17TBK11.98387521
18IKBKB1.92571350
19TYK21.88752999
20KSR21.83495457
21STK101.82908169
22JAK31.76888573
23PAK41.71259881
24PDGFRA1.70434538
25BCR1.69369787
26PIM21.69161436
27MET1.65064757
28TEC1.61698680
29CDK121.57911900
30STK391.57796369
31MAP3K31.53291974
32SCYL21.48930263
33MAP3K61.47282284
34CSK1.43625904
35BMPR1B1.43240724
36EIF2AK11.35888531
37MAP3K81.35662905
38FRK1.33180481
39NME21.30594322
40LATS11.30209459
41IKBKE1.29832681
42TTN1.26178522
43MAP4K11.24175793
44NEK91.22106289
45PIK3CG1.20865519
46BMPR21.18087147
47YES11.15716277
48LATS21.14732482
49MAPKAPK51.13263406
50TTK1.12163858
51ARAF1.11258758
52CSNK1A1L1.09293874
53BTK1.07989411
54ERBB41.07881618
55FGFR31.06658124
56EEF2K1.06640837
57EPHA21.05910760
58FGR1.04552415
59ERN11.04457861
60KIT1.03726197
61MATK1.02323682
62MELK1.01779909
63CSNK1G31.01120295
64STK41.00555873
65TAOK20.98652323
66ICK0.97028771
67MAP3K100.96741796
68CLK10.95307593
69SIK10.95269280
70KSR10.95088376
71PTK20.94000538
72PTK60.93461116
73ACVR1B0.91888796
74MAP3K10.91832844
75FGFR40.91269134
76TXK0.91193774
77ITK0.90129157
78JAK20.89514322
79STK240.89335916
80STK30.88409513
81LYN0.86523395
82ABL10.83367582
83PKN20.83329928
84CHUK0.82837246
85LCK0.79684910
86SYK0.79305224
87CSNK1G10.78920859
88JAK10.78134475
89HCK0.75378576
90RAF10.75371115
91PDGFRB0.74450786
92OXSR10.73933435
93TSSK60.73914749
94DDR20.72038864
95BRSK20.71860771
96LIMK10.71855155
97EPHA30.71629247
98ABL20.71523545
99PKN10.68794866
100SIK30.68763886
101WEE10.68289737
102EIF2AK20.67441757
103MOS0.66779031
104CSNK1G20.66113654
105NEK10.64582076
106MAPKAPK30.64022320
107TAOK30.63197795
108PIM10.62595568
109TGFBR20.62538128
110LRRK20.62232779
111ZAP700.61324913
112IRAK20.61119908
113PLK40.58686247
114GRK10.58270694
115GRK70.57905123
116CDC42BPA0.57763313
117CDK40.57395394
118CDK70.56314148
119RIPK10.56095287
120MAP3K120.54357826
121ERBB30.53641003
122PNCK0.52782563
123TIE10.52672643
124TAOK10.52348255
125BMX0.52248594
126RPS6KB20.51155561
127PRKCQ0.51085445
128PDPK10.48604945
129IRAK10.48113968
130LMTK20.47162146
131RET0.46659682
132MTOR0.45334689
133RPS6KA50.45162430
134PRKCD0.44779667
135TESK20.44749154
136PAK20.44122870
137MARK30.42648315
138MAP3K20.41888381
139FGFR20.41238929
140EIF2AK30.40690341
141BUB10.40509493
142MAPKAPK20.38219568
143MAPK150.33737675
144PRKG20.33514815
145CAMKK20.33259538
146MAP2K30.33201679
147CSF1R0.32807679
148BRAF0.31548518
149CDK60.30916479
150ZAK0.29715801
151MAP2K20.28872608

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051502.94169749
2Graft-versus-host disease_Homo sapiens_hsa053322.67698811
3Leishmaniasis_Homo sapiens_hsa051402.57597726
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.54812020
5Sphingolipid metabolism_Homo sapiens_hsa006002.42603406
6Allograft rejection_Homo sapiens_hsa053302.28669903
7Lysosome_Homo sapiens_hsa041422.25215702
8Legionellosis_Homo sapiens_hsa051342.16037057
9Rheumatoid arthritis_Homo sapiens_hsa053232.10919039
10Toll-like receptor signaling pathway_Homo sapiens_hsa046202.09417026
11NF-kappa B signaling pathway_Homo sapiens_hsa040642.06267553
12NOD-like receptor signaling pathway_Homo sapiens_hsa046212.05992331
13Malaria_Homo sapiens_hsa051442.04496271
14Steroid biosynthesis_Homo sapiens_hsa001001.97943268
15Chronic myeloid leukemia_Homo sapiens_hsa052201.96788058
16Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.91023378
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.89503427
18Pertussis_Homo sapiens_hsa051331.88738973
19Intestinal immune network for IgA production_Homo sapiens_hsa046721.86674627
20Thyroid cancer_Homo sapiens_hsa052161.84892715
21Caffeine metabolism_Homo sapiens_hsa002321.77330840
22Phagosome_Homo sapiens_hsa041451.76973935
23Pancreatic cancer_Homo sapiens_hsa052121.74783618
24Bladder cancer_Homo sapiens_hsa052191.69379637
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.68342415
26Fatty acid elongation_Homo sapiens_hsa000621.67841908
27Tuberculosis_Homo sapiens_hsa051521.66118595
28Asthma_Homo sapiens_hsa053101.64872573
29Acute myeloid leukemia_Homo sapiens_hsa052211.62975522
30Small cell lung cancer_Homo sapiens_hsa052221.61966324
31Osteoclast differentiation_Homo sapiens_hsa043801.57638627
32Hematopoietic cell lineage_Homo sapiens_hsa046401.56162464
33Non-small cell lung cancer_Homo sapiens_hsa052231.55214991
34Ether lipid metabolism_Homo sapiens_hsa005651.51221978
35Autoimmune thyroid disease_Homo sapiens_hsa053201.49411438
36Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.43974610
37Histidine metabolism_Homo sapiens_hsa003401.43023343
38Salmonella infection_Homo sapiens_hsa051321.42701678
39Central carbon metabolism in cancer_Homo sapiens_hsa052301.42135635
40Other glycan degradation_Homo sapiens_hsa005111.39168995
41Proteoglycans in cancer_Homo sapiens_hsa052051.38940176
42Vitamin B6 metabolism_Homo sapiens_hsa007501.38676997
43TNF signaling pathway_Homo sapiens_hsa046681.38659210
44Endometrial cancer_Homo sapiens_hsa052131.38310626
45Adherens junction_Homo sapiens_hsa045201.37926401
46Folate biosynthesis_Homo sapiens_hsa007901.35131695
47Vitamin digestion and absorption_Homo sapiens_hsa049771.33579137
48Renal cell carcinoma_Homo sapiens_hsa052111.32695525
49Prostate cancer_Homo sapiens_hsa052151.31143944
50Measles_Homo sapiens_hsa051621.29928759
51RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.24940464
52Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.23390169
53Focal adhesion_Homo sapiens_hsa045101.21225308
54Chemokine signaling pathway_Homo sapiens_hsa040621.21169116
55Cell cycle_Homo sapiens_hsa041101.19829508
56Arachidonic acid metabolism_Homo sapiens_hsa005901.19618029
57Leukocyte transendothelial migration_Homo sapiens_hsa046701.17006237
58SNARE interactions in vesicular transport_Homo sapiens_hsa041301.16798180
59Toxoplasmosis_Homo sapiens_hsa051451.16739330
60Antigen processing and presentation_Homo sapiens_hsa046121.12713303
61Viral carcinogenesis_Homo sapiens_hsa052031.10105389
62Type I diabetes mellitus_Homo sapiens_hsa049401.09808535
63Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.09013685
64MicroRNAs in cancer_Homo sapiens_hsa052061.08792712
65Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.07004586
66VEGF signaling pathway_Homo sapiens_hsa043701.02590247
67Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.00756131
68Sulfur metabolism_Homo sapiens_hsa009201.00713488
69B cell receptor signaling pathway_Homo sapiens_hsa046621.00052274
70Prolactin signaling pathway_Homo sapiens_hsa049170.99771282
71Glioma_Homo sapiens_hsa052140.96994725
72Linoleic acid metabolism_Homo sapiens_hsa005910.96907601
73Jak-STAT signaling pathway_Homo sapiens_hsa046300.95868999
74African trypanosomiasis_Homo sapiens_hsa051430.95136094
75Regulation of autophagy_Homo sapiens_hsa041400.93968009
76Neurotrophin signaling pathway_Homo sapiens_hsa047220.93661079
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.93466165
78mTOR signaling pathway_Homo sapiens_hsa041500.92677028
79Shigellosis_Homo sapiens_hsa051310.92440861
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.91386709
81Influenza A_Homo sapiens_hsa051640.89932843
82Complement and coagulation cascades_Homo sapiens_hsa046100.89726023
83Apoptosis_Homo sapiens_hsa042100.89519106
84DNA replication_Homo sapiens_hsa030300.88185832
85Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.84560263
86Herpes simplex infection_Homo sapiens_hsa051680.83975673
87Colorectal cancer_Homo sapiens_hsa052100.83645948
88alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.81125381
89Sphingolipid signaling pathway_Homo sapiens_hsa040710.80774253
90HTLV-I infection_Homo sapiens_hsa051660.80495450
91Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.80368487
92ErbB signaling pathway_Homo sapiens_hsa040120.80198436
93Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.79170151
94Protein export_Homo sapiens_hsa030600.78125176
95Hepatitis C_Homo sapiens_hsa051600.76216277
96Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.69299435
97Epstein-Barr virus infection_Homo sapiens_hsa051690.68970904
98Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.68028160
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.67528213
100p53 signaling pathway_Homo sapiens_hsa041150.66356452
101HIF-1 signaling pathway_Homo sapiens_hsa040660.66341429
102Amoebiasis_Homo sapiens_hsa051460.66225386
103Glycosaminoglycan degradation_Homo sapiens_hsa005310.65419826
104Insulin signaling pathway_Homo sapiens_hsa049100.65280245
105Galactose metabolism_Homo sapiens_hsa000520.65070137
106ABC transporters_Homo sapiens_hsa020100.64318808
107Hepatitis B_Homo sapiens_hsa051610.63538676
108Cyanoamino acid metabolism_Homo sapiens_hsa004600.63002017
109Primary immunodeficiency_Homo sapiens_hsa053400.62984937
110N-Glycan biosynthesis_Homo sapiens_hsa005100.62950555
111Melanoma_Homo sapiens_hsa052180.62838123
112Mineral absorption_Homo sapiens_hsa049780.62834730
113Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.62757190
114mRNA surveillance pathway_Homo sapiens_hsa030150.62362136
115Non-homologous end-joining_Homo sapiens_hsa034500.60749247
116Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.60644652
117Vibrio cholerae infection_Homo sapiens_hsa051100.59535883
118Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.59442738
119Platelet activation_Homo sapiens_hsa046110.59326771
120Pathways in cancer_Homo sapiens_hsa052000.59099246
121Retinol metabolism_Homo sapiens_hsa008300.56082709
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.55367956
123Phosphatidylinositol signaling system_Homo sapiens_hsa040700.54274788
124Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53750914
125PI3K-Akt signaling pathway_Homo sapiens_hsa041510.53644935
126GnRH signaling pathway_Homo sapiens_hsa049120.53107848
127Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.52771653
128Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.52571742
129Estrogen signaling pathway_Homo sapiens_hsa049150.52257881
130Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51347003
131Prion diseases_Homo sapiens_hsa050200.46324443
132Endocytosis_Homo sapiens_hsa041440.46175092
133Fatty acid biosynthesis_Homo sapiens_hsa000610.44750773
134Adipocytokine signaling pathway_Homo sapiens_hsa049200.39444782
135Pentose and glucuronate interconversions_Homo sapiens_hsa000400.38266718
136AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.37307085
137Inositol phosphate metabolism_Homo sapiens_hsa005620.36820482
138T cell receptor signaling pathway_Homo sapiens_hsa046600.35956196
139Viral myocarditis_Homo sapiens_hsa054160.35738325
140Peroxisome_Homo sapiens_hsa041460.35312277
141Renin-angiotensin system_Homo sapiens_hsa046140.34280583
142Phenylalanine metabolism_Homo sapiens_hsa003600.34055452
143Glutathione metabolism_Homo sapiens_hsa004800.33742582
144Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.31155778
145Pentose phosphate pathway_Homo sapiens_hsa000300.30927045
146ECM-receptor interaction_Homo sapiens_hsa045120.30907028
147Ovarian steroidogenesis_Homo sapiens_hsa049130.29124568

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