MGA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)6.87166205
2nuclear pore organization (GO:0006999)6.47380726
3pore complex assembly (GO:0046931)5.20053979
4mitotic sister chromatid cohesion (GO:0007064)4.70948279
5pre-miRNA processing (GO:0031054)4.66344845
6histone H4-K12 acetylation (GO:0043983)4.41474728
7protein localization to kinetochore (GO:0034501)4.37020894
8regulation of nuclear cell cycle DNA replication (GO:0033262)4.36291915
9cytoplasmic mRNA processing body assembly (GO:0033962)4.11115403
10regulation of histone H3-K9 methylation (GO:0051570)4.03554886
11histone H4-K8 acetylation (GO:0043982)4.02154584
12histone H4-K5 acetylation (GO:0043981)4.02154584
13regulation of centriole replication (GO:0046599)3.99290980
14negative regulation of histone methylation (GO:0031061)3.97719327
15regulation of telomere maintenance via telomerase (GO:0032210)3.93605022
16interkinetic nuclear migration (GO:0022027)3.89750343
17histone H3-K4 methylation (GO:0051568)3.87997165
18regulation of RNA export from nucleus (GO:0046831)3.87572687
19histone H3-K4 trimethylation (GO:0080182)3.81710584
20sister chromatid segregation (GO:0000819)3.80585367
21DNA geometric change (GO:0032392)3.79360320
22mitotic chromosome condensation (GO:0007076)3.78003756
23DNA duplex unwinding (GO:0032508)3.77814555
24chromatin assembly (GO:0031497)3.72187051
25histone H4-K16 acetylation (GO:0043984)3.66394240
26negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)3.66082939
27regulation of posttranscriptional gene silencing (GO:0060147)3.65730353
28regulation of gene silencing by miRNA (GO:0060964)3.65730353
29regulation of gene silencing by RNA (GO:0060966)3.65730353
30heterochromatin organization (GO:0070828)3.61805628
31mitotic sister chromatid segregation (GO:0000070)3.59140922
32polyketide metabolic process (GO:0030638)3.55538963
33doxorubicin metabolic process (GO:0044598)3.55538963
34daunorubicin metabolic process (GO:0044597)3.55538963
35regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.52196095
36microtubule anchoring (GO:0034453)3.48630084
37negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)3.48400762
38regulation of centrosome duplication (GO:0010824)3.48268580
39regulation of helicase activity (GO:0051095)3.47949664
40synapsis (GO:0007129)3.46695297
41mitotic nuclear envelope disassembly (GO:0007077)3.43130273
42DNA replication-dependent nucleosome organization (GO:0034723)3.42734933
43DNA replication-dependent nucleosome assembly (GO:0006335)3.42734933
44protein localization to chromosome, centromeric region (GO:0071459)3.40571304
45DNA unwinding involved in DNA replication (GO:0006268)3.40115130
46negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.38867670
47negative regulation of translation, ncRNA-mediated (GO:0040033)3.38867670
48regulation of translation, ncRNA-mediated (GO:0045974)3.38867670
49regulation of centrosome cycle (GO:0046605)3.34431756
50protein K11-linked deubiquitination (GO:0035871)3.34314627
51regulation of telomere maintenance (GO:0032204)3.33837841
52centrosome duplication (GO:0051298)3.33585874
53regulation of DNA endoreduplication (GO:0032875)3.32130173
54negative regulation of cell cycle G2/M phase transition (GO:1902750)3.29936769
55positive regulation of DNA-dependent DNA replication (GO:2000105)3.28920181
56phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.27452514
57membrane disassembly (GO:0030397)3.24387838
58nuclear envelope disassembly (GO:0051081)3.24387838
59regulation of gene silencing (GO:0060968)3.20976452
60NLS-bearing protein import into nucleus (GO:0006607)3.18983059
61peptidyl-lysine trimethylation (GO:0018023)3.17780309
62histone-serine phosphorylation (GO:0035404)3.16090076
63histone H3-K9 methylation (GO:0051567)3.13445573
64positive regulation of mitotic sister chromatid separation (GO:1901970)3.09175846
65positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.09175846
66positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.09175846
67replication fork processing (GO:0031297)3.07973822
68sister chromatid cohesion (GO:0007062)3.07935803
69regulation of chromatin silencing (GO:0031935)3.07170378
70protein K48-linked deubiquitination (GO:0071108)3.06494752
71negative regulation of DNA-dependent DNA replication (GO:2000104)3.06311599
72RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.06210655
73protein prenylation (GO:0018342)3.03290188
74prenylation (GO:0097354)3.03290188
75positive regulation of histone H3-K4 methylation (GO:0051571)3.02431437
76rRNA catabolic process (GO:0016075)3.02372355
77genitalia morphogenesis (GO:0035112)3.02168170
78negative regulation of DNA repair (GO:0045738)3.02102339
79paraxial mesoderm development (GO:0048339)3.01357766
80DNA conformation change (GO:0071103)3.00574857
81negative regulation of chromatin modification (GO:1903309)2.99199091
82determination of adult lifespan (GO:0008340)2.97678012
83peptidyl-lysine methylation (GO:0018022)2.97636489
84regulation of DNA-dependent DNA replication (GO:0090329)2.95984500
85regulation of mitotic spindle organization (GO:0060236)2.95257551
86regulation of nucleobase-containing compound transport (GO:0032239)2.94803384
87establishment of protein localization to Golgi (GO:0072600)2.94577887
88notochord development (GO:0030903)2.94565256
89meiotic chromosome segregation (GO:0045132)2.93924931
90replicative senescence (GO:0090399)2.93772128
91histone lysine methylation (GO:0034968)2.93457748
92dorsal/ventral axis specification (GO:0009950)2.93369753
93RNA stabilization (GO:0043489)2.93205007
94mRNA stabilization (GO:0048255)2.93205007
95histone mRNA catabolic process (GO:0071044)2.92990607
96nucleus localization (GO:0051647)2.92034898
97regulation of protein polyubiquitination (GO:1902914)2.88526098
98monoubiquitinated protein deubiquitination (GO:0035520)2.88499706
99regulation of spindle organization (GO:0090224)2.88451897
100histone lysine demethylation (GO:0070076)2.87336122
101histone H2A monoubiquitination (GO:0035518)2.87107044
102regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.86876037
103chromatin assembly or disassembly (GO:0006333)2.84638059
104histone H3-K36 demethylation (GO:0070544)2.84354379
105regulation of histone methylation (GO:0031060)2.84140986
106snRNA transcription (GO:0009301)2.83939369
107DNA replication checkpoint (GO:0000076)2.83691719
108kinetochore organization (GO:0051383)2.83610467
109histone H3-K9 demethylation (GO:0033169)2.83262706
110regulation of histone H3-K4 methylation (GO:0051569)2.82985661
111positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.82666904
112maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.82398589
113mitotic metaphase plate congression (GO:0007080)2.80093215
114double-strand break repair via nonhomologous end joining (GO:0006303)2.79885267
115non-recombinational repair (GO:0000726)2.79885267
116microtubule organizing center organization (GO:0031023)2.79273399
117histone demethylation (GO:0016577)2.78720394
118neural tube formation (GO:0001841)2.78301648
119double-strand break repair via homologous recombination (GO:0000724)2.77753943
120negative regulation of histone modification (GO:0031057)2.76442182
121dosage compensation (GO:0007549)2.75997637
122regulation of double-strand break repair (GO:2000779)2.75547042
123histone H3-K9 modification (GO:0061647)2.75314131
124regulation of establishment of cell polarity (GO:2000114)2.74392502
125regulation of hippo signaling (GO:0035330)2.73937058
126translesion synthesis (GO:0019985)2.73917300
127metaphase plate congression (GO:0051310)2.73427863
128gene silencing by RNA (GO:0031047)2.73232400
129recombinational repair (GO:0000725)2.73157698
130somatic hypermutation of immunoglobulin genes (GO:0016446)2.72675104
131somatic diversification of immune receptors via somatic mutation (GO:0002566)2.72675104
132mRNA transport (GO:0051028)2.70968859
133centrosome organization (GO:0051297)2.70247619
134ncRNA catabolic process (GO:0034661)2.68824567
135histone methylation (GO:0016571)2.67976734
136positive regulation of chromosome segregation (GO:0051984)2.67839482
137spindle assembly (GO:0051225)2.67745086
138somatic recombination of immunoglobulin gene segments (GO:0016447)2.67535521
139nucleus organization (GO:0006997)2.66869965
140centriole replication (GO:0007099)2.66637099
141IMP biosynthetic process (GO:0006188)2.66228899
142protein targeting to Golgi (GO:0000042)2.59546632
143reciprocal meiotic recombination (GO:0007131)2.59395224
144reciprocal DNA recombination (GO:0035825)2.59395224
145DNA synthesis involved in DNA repair (GO:0000731)2.58599232
146retrograde transport, vesicle recycling within Golgi (GO:0000301)2.55886825
147somatic cell DNA recombination (GO:0016444)2.53187698
148somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.53187698
149V(D)J recombination (GO:0033151)2.52462954
150regulation of pigment cell differentiation (GO:0050932)2.51924514
151regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.50177899
152positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.50177899
153positive regulation of developmental pigmentation (GO:0048087)2.49230556
154gastrulation with mouth forming second (GO:0001702)2.45811246
155somatic diversification of immunoglobulins (GO:0016445)2.44092083
156anterior/posterior axis specification, embryo (GO:0008595)2.41572261
157positive regulation of mRNA 3-end processing (GO:0031442)2.40284046
158TOR signaling (GO:0031929)2.39722249

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.97352301
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.51814616
3SALL1_21062744_ChIP-ChIP_HESCs_Human4.32151100
4E2F4_17652178_ChIP-ChIP_JURKAT_Human4.12634323
5KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.89552615
6KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.89552615
7KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.89552615
8* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.66180908
9EGR1_19374776_ChIP-ChIP_THP-1_Human3.32071566
10TP63_19390658_ChIP-ChIP_HaCaT_Human3.27068373
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.00720859
12GBX2_23144817_ChIP-Seq_PC3_Human2.66115417
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.58659924
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.50680835
15HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.43630264
16SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.37770898
17SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.26499639
18AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.20253532
19ZFP57_27257070_Chip-Seq_ESCs_Mouse2.18928786
20ZNF274_21170338_ChIP-Seq_K562_Hela2.13021945
21TAF15_26573619_Chip-Seq_HEK293_Human2.06983389
22SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.04595308
23TCF3_18692474_ChIP-Seq_MESCs_Mouse2.02078109
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.97756755
25E2F1_21310950_ChIP-Seq_MCF-7_Human1.93524303
26GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.93288271
27NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.91067788
28* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.91062552
29SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.85984765
30P300_19829295_ChIP-Seq_ESCs_Human1.83926463
31POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.80606917
32* STAT3_23295773_ChIP-Seq_U87_Human1.78922316
33IGF1R_20145208_ChIP-Seq_DFB_Human1.76687394
34RBPJ_22232070_ChIP-Seq_NCS_Mouse1.75073343
35SMAD4_21799915_ChIP-Seq_A2780_Human1.72051666
36MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.70580251
37ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.69683927
38MYC_18555785_ChIP-Seq_MESCs_Mouse1.69044051
39YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.66135030
40PIAS1_25552417_ChIP-Seq_VCAP_Human1.61408872
41ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.60935285
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.59098620
43SOX2_18555785_ChIP-Seq_MESCs_Mouse1.58926763
44ER_23166858_ChIP-Seq_MCF-7_Human1.58497306
45* TCF4_23295773_ChIP-Seq_U87_Human1.56297370
46CTBP2_25329375_ChIP-Seq_LNCAP_Human1.54913002
47TCF3_18692474_ChIP-Seq_MEFs_Mouse1.53961033
48MYC_19079543_ChIP-ChIP_MESCs_Mouse1.53902059
49BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.52114777
50RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.51863315
51NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.51137167
52NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.50007591
53FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.47739151
54POU5F1_16153702_ChIP-ChIP_HESCs_Human1.47396987
55NANOG_18555785_ChIP-Seq_MESCs_Mouse1.43305484
56AR_21572438_ChIP-Seq_LNCaP_Human1.41440286
57* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.39985774
58GATA1_22025678_ChIP-Seq_K562_Human1.39817735
59VDR_22108803_ChIP-Seq_LS180_Human1.39797286
60POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.39305601
61OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.39053714
62UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.38983174
63FOXM1_26456572_ChIP-Seq_MCF-7_Human1.38833665
64SMAD3_21741376_ChIP-Seq_EPCs_Human1.38001747
65PCGF2_27294783_Chip-Seq_ESCs_Mouse1.37913688
66SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.37187084
67AR_21909140_ChIP-Seq_LNCAP_Human1.36802344
68ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.36380943
69* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.35374086
70* MYC_22102868_ChIP-Seq_BL_Human1.35326686
71CTBP1_25329375_ChIP-Seq_LNCAP_Human1.35174319
72CIITA_25753668_ChIP-Seq_RAJI_Human1.35024962
73NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.34331170
74NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.33871693
75TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.33326809
76TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33078313
77POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.33078313
78EZH2_22144423_ChIP-Seq_EOC_Human1.32736504
79AHR_22903824_ChIP-Seq_MCF-7_Human1.32622549
80ZNF217_24962896_ChIP-Seq_MCF-7_Human1.32427979
81SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31199605
82SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30245727
83BP1_19119308_ChIP-ChIP_Hs578T_Human1.29052314
84POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.28899510
85* NANOG_18555785_Chip-Seq_ESCs_Mouse1.28079484
86ARNT_22903824_ChIP-Seq_MCF-7_Human1.27360220
87EZH2_27294783_Chip-Seq_NPCs_Mouse1.25399247
88NELFA_20434984_ChIP-Seq_ESCs_Mouse1.24980929
89MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.24070358
90TBX3_20139965_ChIP-Seq_ESCs_Mouse1.23584189
91MYCN_18555785_ChIP-Seq_MESCs_Mouse1.23583514
92TOP2B_26459242_ChIP-Seq_MCF-7_Human1.23412417
93CBP_20019798_ChIP-Seq_JUKART_Human1.23224638
94IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.23224638
95SUZ12_27294783_Chip-Seq_NPCs_Mouse1.23118886
96TBX3_20139965_ChIP-Seq_MESCs_Mouse1.21975962
97MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.20595465
98AR_25329375_ChIP-Seq_VCAP_Human1.19836842
99TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.18437908
100SMAD_19615063_ChIP-ChIP_OVARY_Human1.18359564
101POU5F1_16518401_ChIP-PET_MESCs_Mouse1.18112882
102CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.18075997
103CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.18070521
104* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.17709739
105FUS_26573619_Chip-Seq_HEK293_Human1.16476155
106BCAT_22108803_ChIP-Seq_LS180_Human1.15405631
107NR3C1_21868756_ChIP-Seq_MCF10A_Human1.14989092
108PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.14903057
109PCGF2_27294783_Chip-Seq_NPCs_Mouse1.14648878
110* E2F1_18555785_Chip-Seq_ESCs_Mouse1.13649168
111RUNX2_22187159_ChIP-Seq_PCA_Human1.11900614
112PADI4_21655091_ChIP-ChIP_MCF-7_Human1.11515021
113SOX9_26525672_Chip-Seq_HEART_Mouse1.11074223
114NFE2_27457419_Chip-Seq_LIVER_Mouse1.10941490
115STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09663769
116ELK1_19687146_ChIP-ChIP_HELA_Human1.08244121
117* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07131679
118* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.07093715
119CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.06773347
120FLI1_21867929_ChIP-Seq_TH2_Mouse1.04973641
121P53_22387025_ChIP-Seq_ESCs_Mouse1.04001853
122SOX2_16153702_ChIP-ChIP_HESCs_Human1.03773522
123PKCTHETA_26484144_Chip-Seq_BREAST_Human1.03269541
124PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.03143093
125IRF1_19129219_ChIP-ChIP_H3396_Human1.03119961
126ZFP281_27345836_Chip-Seq_ESCs_Mouse1.03097030
127PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.02861565
128NOTCH1_21737748_ChIP-Seq_TLL_Human1.02461617
129NANOG_21062744_ChIP-ChIP_HESCs_Human1.02319212
130TCF4_22108803_ChIP-Seq_LS180_Human1.01643720
131NANOG_18692474_ChIP-Seq_MESCs_Mouse1.00960198
132* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.00485103
133TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.00095660
134SOX2_21211035_ChIP-Seq_LN229_Gbm0.99204759
135* CMYC_18555785_Chip-Seq_ESCs_Mouse0.98595456
136CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.97567265
137NANOG_16518401_ChIP-PET_MESCs_Mouse0.97288263
138PRDM14_20953172_ChIP-Seq_ESCs_Human0.96559084
139MYC_18940864_ChIP-ChIP_HL60_Human0.96274438
140NANOG_16153702_ChIP-ChIP_HESCs_Human0.96122298
141* P300_18555785_Chip-Seq_ESCs_Mouse0.96099244
142* SUZ12_18555785_Chip-Seq_ESCs_Mouse0.95794318
143CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.95787742
144SOX2_18692474_ChIP-Seq_MESCs_Mouse0.94002648
145STAT3_1855785_ChIP-Seq_MESCs_Mouse0.90153024
146ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.90027596
147SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.89428969
148* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88779503
149EWS_26573619_Chip-Seq_HEK293_Human0.88660097
150DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.88158764
151FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.87605034
152* KDM5A_27292631_Chip-Seq_BREAST_Human0.87134915
153GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.83767451
154* BRD4_25478319_ChIP-Seq_HGPS_Human0.83676968
155TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.83105457
156TCF7_22412390_ChIP-Seq_EML_Mouse0.81488253
157HIF1A_21447827_ChIP-Seq_MCF-7_Human0.80829221
158FOXP3_21729870_ChIP-Seq_TREG_Human0.76994762
159STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.75633458
160* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.75624455
161FLI1_27457419_Chip-Seq_LIVER_Mouse0.75188458
162TCF4_18268006_ChIP-ChIP_LS174T_Human0.72097185
163TP53_16413492_ChIP-PET_HCT116_Human0.71686503
164STAT3_18555785_ChIP-Seq_MESCs_Mouse0.71665448
165* CHD1_26751641_Chip-Seq_LNCaP_Human0.70841417
166STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.67038649
167TFEB_21752829_ChIP-Seq_HELA_Human0.66894080

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.54187804
2MP0010094_abnormal_chromosome_stability3.12883925
3MP0003121_genomic_imprinting3.08943595
4MP0003890_abnormal_embryonic-extraembry3.00872510
5MP0003787_abnormal_imprinting2.73646429
6MP0003111_abnormal_nucleus_morphology2.71523888
7MP0010352_gastrointestinal_tract_polyps2.67422423
8MP0003077_abnormal_cell_cycle2.60549042
9MP0004264_abnormal_extraembryonic_tissu2.47699078
10MP0004957_abnormal_blastocyst_morpholog2.46610361
11MP0006292_abnormal_olfactory_placode2.43673262
12MP0000569_abnormal_digit_pigmentation2.39368780
13MP0008058_abnormal_DNA_repair2.35860357
14MP0003123_paternal_imprinting2.23674658
15MP0008877_abnormal_DNA_methylation2.18587840
16MP0010307_abnormal_tumor_latency2.06336104
17MP0003693_abnormal_embryo_hatching1.97177963
18MP0001293_anophthalmia1.96515545
19MP0003122_maternal_imprinting1.93802311
20MP0002396_abnormal_hematopoietic_system1.93586281
21MP0005380_embryogenesis_phenotype1.92812846
22MP0001672_abnormal_embryogenesis/_devel1.92812846
23MP0000350_abnormal_cell_proliferation1.92520840
24MP0008007_abnormal_cellular_replicative1.86923737
25MP0003646_muscle_fatigue1.86342727
26MP0005076_abnormal_cell_differentiation1.80555828
27MP0003984_embryonic_growth_retardation1.77215022
28MP0002088_abnormal_embryonic_growth/wei1.76968686
29MP0002084_abnormal_developmental_patter1.75227337
30MP0004197_abnormal_fetal_growth/weight/1.71604395
31MP0009697_abnormal_copulation1.69900132
32MP0002086_abnormal_extraembryonic_tissu1.68463902
33MP0001661_extended_life_span1.64867177
34MP0002085_abnormal_embryonic_tissue1.63848682
35MP0003718_maternal_effect1.61144529
36MP0001730_embryonic_growth_arrest1.53075312
37MP0002160_abnormal_reproductive_system1.46775428
38MP0009703_decreased_birth_body1.39575568
39MP0000631_abnormal_neuroendocrine_gland1.37740063
40MP0003937_abnormal_limbs/digits/tail_de1.37094713
41MP0003935_abnormal_craniofacial_develop1.36783454
42MP0000427_abnormal_hair_cycle1.36178992
43MP0001697_abnormal_embryo_size1.35752355
44MP0000432_abnormal_head_morphology1.33406556
45MP0003786_premature_aging1.32708848
46MP0005394_taste/olfaction_phenotype1.31830487
47MP0005499_abnormal_olfactory_system1.31830487
48MP0004808_abnormal_hematopoietic_stem1.29709390
49MP0002092_abnormal_eye_morphology1.25603447
50MP0000428_abnormal_craniofacial_morphol1.22979700
51MP0005187_abnormal_penis_morphology1.22850791
52MP0003119_abnormal_digestive_system1.19382611
53MP0002009_preneoplasia1.18816044
54MP0002254_reproductive_system_inflammat1.16796353
55MP0005248_abnormal_Harderian_gland1.16567772
56MP0005367_renal/urinary_system_phenotyp1.16047007
57MP0000516_abnormal_urinary_system1.16047007
58MP0002877_abnormal_melanocyte_morpholog1.13774619
59MP0008932_abnormal_embryonic_tissue1.13632470
60MP0002166_altered_tumor_susceptibility1.13316462
61MP0003943_abnormal_hepatobiliary_system1.11044927
62MP0002080_prenatal_lethality1.10728522
63MP0005174_abnormal_tail_pigmentation1.10134514
64MP0002925_abnormal_cardiovascular_devel1.09491203
65MP0003755_abnormal_palate_morphology1.09289808
66MP0001286_abnormal_eye_development1.09198274
67MP0000537_abnormal_urethra_morphology1.08029272
68MP0010030_abnormal_orbit_morphology1.06930358
69MP0008995_early_reproductive_senescence1.05836502
70MP0003567_abnormal_fetal_cardiomyocyte1.05284473
71MP0003941_abnormal_skin_development1.03700773
72MP0005253_abnormal_eye_physiology1.03442140
73MP0003705_abnormal_hypodermis_morpholog1.01610449
74MP0004145_abnormal_muscle_electrophysio1.01117249
75MP0005220_abnormal_exocrine_pancreas1.00557289
76MP0010234_abnormal_vibrissa_follicle1.00359202
77MP0002233_abnormal_nose_morphology1.00222500
78MP0000313_abnormal_cell_death0.98683754
79MP0005646_abnormal_pituitary_gland0.98652233
80MP0002697_abnormal_eye_size0.98649981
81MP0002751_abnormal_autonomic_nervous0.98367555
82MP0000383_abnormal_hair_follicle0.97909021
83MP0010678_abnormal_skin_adnexa0.95313879
84MP0005391_vision/eye_phenotype0.95214698
85MP0005257_abnormal_intraocular_pressure0.94236074
86MP0005075_abnormal_melanosome_morpholog0.94217255
87MP0003950_abnormal_plasma_membrane0.92872297
88MP0002938_white_spotting0.92842251
89MP0002102_abnormal_ear_morphology0.92823641
90MP0000653_abnormal_sex_gland0.91341430
91MP0005389_reproductive_system_phenotype0.90869269
92MP0002210_abnormal_sex_determination0.90496023
93MP0002114_abnormal_axial_skeleton0.89813670
94MP0001849_ear_inflammation0.88516249
95MP0002127_abnormal_cardiovascular_syste0.88262522
96MP0002653_abnormal_ependyma_morphology0.87995404
97MP0001119_abnormal_female_reproductive0.87329875
98MP0001485_abnormal_pinna_reflex0.86309923
99MP0000490_abnormal_crypts_of0.85250962
100MP0000647_abnormal_sebaceous_gland0.85211363
101MP0006072_abnormal_retinal_apoptosis0.84736703
102MP0001145_abnormal_male_reproductive0.84585175
103MP0003861_abnormal_nervous_system0.84529361
104MP0002116_abnormal_craniofacial_bone0.84431358
105MP0003698_abnormal_male_reproductive0.84048613
106MP0005395_other_phenotype0.81954640
107MP0002638_abnormal_pupillary_reflex0.81845162
108MP0005645_abnormal_hypothalamus_physiol0.81448300
109MP0002928_abnormal_bile_duct0.80657236
110MP0005551_abnormal_eye_electrophysiolog0.80632461
111MP0001177_atelectasis0.79846149
112MP0000778_abnormal_nervous_system0.79110200
113MP0002075_abnormal_coat/hair_pigmentati0.79035987
114MP0009672_abnormal_birth_weight0.78147541
115MP0003566_abnormal_cell_adhesion0.77053678
116MP0002111_abnormal_tail_morphology0.76653705
117MP0002932_abnormal_joint_morphology0.76113475
118MP0004134_abnormal_chest_morphology0.76020090
119MP0000703_abnormal_thymus_morphology0.75354268
120MP0004133_heterotaxia0.74419210
121MP0000049_abnormal_middle_ear0.73780512
122MP0002282_abnormal_trachea_morphology0.73521800
123MP0003936_abnormal_reproductive_system0.73377468
124MP0000733_abnormal_muscle_development0.73041369
125MP0003699_abnormal_female_reproductive0.72911810
126MP0005384_cellular_phenotype0.72817765
127MP0002095_abnormal_skin_pigmentation0.72649420
128MP0003195_calcinosis0.71863095
129MP0002109_abnormal_limb_morphology0.71279149
130MP0002019_abnormal_tumor_incidence0.71175961
131MP0005621_abnormal_cell_physiology0.70619780
132MP0004130_abnormal_muscle_cell0.70169036
133MP0008770_decreased_survivor_rate0.68006904
134MP0003183_abnormal_peptide_metabolism0.67941218
135MP0000266_abnormal_heart_morphology0.67731316
136MP0003385_abnormal_body_wall0.67633960
137MP0000371_diluted_coat_color0.67221205
138MP0003942_abnormal_urinary_system0.66831395
139MP0001915_intracranial_hemorrhage0.66733858
140MP0001986_abnormal_taste_sensitivity0.66488168
141MP0002006_tumorigenesis0.66251047
142MP0001929_abnormal_gametogenesis0.66157300

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.11633632
2Volvulus (HP:0002580)4.09000597
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.01877014
4Ependymoma (HP:0002888)3.96025783
5Astrocytoma (HP:0009592)3.39319772
6Abnormality of the astrocytes (HP:0100707)3.39319772
7Hypochromic microcytic anemia (HP:0004840)3.32644691
8Neoplasm of the oral cavity (HP:0100649)3.24419454
9Glioma (HP:0009733)3.09550111
10Medulloblastoma (HP:0002885)3.06847469
11Nephroblastoma (Wilms tumor) (HP:0002667)2.93033419
12Bilateral microphthalmos (HP:0007633)2.88258940
13Rhabdomyosarcoma (HP:0002859)2.88081374
14Hepatoblastoma (HP:0002884)2.82703533
15Abnormality of the fingertips (HP:0001211)2.80308087
16Abnormality of the labia minora (HP:0012880)2.76146759
17Neoplasm of striated muscle (HP:0009728)2.73736419
18Rib fusion (HP:0000902)2.73190510
19Chronic hepatic failure (HP:0100626)2.71779517
20Embryonal renal neoplasm (HP:0011794)2.71399648
21Gaze-evoked nystagmus (HP:0000640)2.70288011
22Hyperventilation (HP:0002883)2.69399288
23Abnormality of chromosome stability (HP:0003220)2.65263009
24Aplasia/Hypoplasia of the uvula (HP:0010293)2.58347836
25Neoplasm of the adrenal cortex (HP:0100641)2.49686808
26Meckel diverticulum (HP:0002245)2.49204891
27Ectopic kidney (HP:0000086)2.48674271
28Acute myeloid leukemia (HP:0004808)2.47057455
29Intestinal fistula (HP:0100819)2.46986755
30Papillary thyroid carcinoma (HP:0002895)2.45311371
31Protruding tongue (HP:0010808)2.43981872
32Fair hair (HP:0002286)2.42569263
33Long eyelashes (HP:0000527)2.41385043
34Supernumerary ribs (HP:0005815)2.41131125
35Absent frontal sinuses (HP:0002688)2.40613453
36Prominent nose (HP:0000448)2.36535833
37Abnormality of the ileum (HP:0001549)2.35660521
38Genetic anticipation (HP:0003743)2.34274146
39Shawl scrotum (HP:0000049)2.32904561
40Impulsivity (HP:0100710)2.29427983
41Hypoplastic labia majora (HP:0000059)2.25927489
42Pancreatic cysts (HP:0001737)2.23996411
43Supernumerary bones of the axial skeleton (HP:0009144)2.21284809
44Abnormality of the renal cortex (HP:0011035)2.20305073
45Colon cancer (HP:0003003)2.20277250
46Aplasia/Hypoplasia of the sternum (HP:0006714)2.19573488
47Urethral obstruction (HP:0000796)2.19052100
48Abnormality of the renal collecting system (HP:0004742)2.17571905
49Anal stenosis (HP:0002025)2.17062915
50Lip pit (HP:0100267)2.16628445
51Tubulointerstitial nephritis (HP:0001970)2.16516594
52Abnormality of DNA repair (HP:0003254)2.16183471
53Increased nuchal translucency (HP:0010880)2.14517743
54Duplicated collecting system (HP:0000081)2.13583673
55Myelodysplasia (HP:0002863)2.13326434
56Broad thumb (HP:0011304)2.06915956
57Abnormality of chromosome segregation (HP:0002916)2.05171204
58Thyroid carcinoma (HP:0002890)2.04866854
59Short 4th metacarpal (HP:0010044)2.03371621
60Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.03371621
61Short humerus (HP:0005792)2.01752661
62Gastrointestinal carcinoma (HP:0002672)2.01056424
63Malignant gastrointestinal tract tumors (HP:0006749)2.01056424
64Small intestinal stenosis (HP:0012848)2.00619444
65Duodenal stenosis (HP:0100867)2.00619444
66Supernumerary spleens (HP:0009799)2.00479090
67Rectovaginal fistula (HP:0000143)2.00245291
68Rectal fistula (HP:0100590)2.00245291
69Abnormality of the labia majora (HP:0012881)2.00209031
70Abnormality of the nasal septum (HP:0000419)1.99745214
71Submucous cleft hard palate (HP:0000176)1.99639354
72Abnormality of the renal medulla (HP:0100957)1.98913997
73Macroorchidism (HP:0000053)1.98545943
74Deep philtrum (HP:0002002)1.98435372
75Absent radius (HP:0003974)1.98310195
76Oligodactyly (hands) (HP:0001180)1.98054195
77Heterotopia (HP:0002282)1.97784143
78Abnormality of the lower motor neuron (HP:0002366)1.97671266
79Abnormality of the parathyroid morphology (HP:0011766)1.97526703
80Pancreatic fibrosis (HP:0100732)1.97056918
81Truncal obesity (HP:0001956)1.96378182
82Abnormality of the preputium (HP:0100587)1.95470244
83Renal cortical cysts (HP:0000803)1.94239396
84Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.92937680
85Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.91831013
86Short 1st metacarpal (HP:0010034)1.91831013
87Aplasia/Hypoplasia of the tibia (HP:0005772)1.91694142
88Nephronophthisis (HP:0000090)1.91416903
89Short chin (HP:0000331)1.91282310
90Large earlobe (HP:0009748)1.90108308
91Abnormal number of incisors (HP:0011064)1.90067728
92Deviation of the thumb (HP:0009603)1.89986875
93Aplasia/hypoplasia of the humerus (HP:0006507)1.89420863
94Drooling (HP:0002307)1.89357870
95Abnormality of the carotid arteries (HP:0005344)1.88249296
96Abnormality of the salivary glands (HP:0010286)1.86489198
97Thyroiditis (HP:0100646)1.86050870
98Acute lymphatic leukemia (HP:0006721)1.85851562
99Skin tags (HP:0010609)1.85190774
100Abnormality of the ischium (HP:0003174)1.84994817
101Aplasia involving forearm bones (HP:0009822)1.83860665
102Absent forearm bone (HP:0003953)1.83860665
103Tented upper lip vermilion (HP:0010804)1.83573913
104Renal duplication (HP:0000075)1.83302081
105Aqueductal stenosis (HP:0002410)1.82791731
106Abnormality of the incisor (HP:0000676)1.82434202
107Proximal placement of thumb (HP:0009623)1.81529436
108Abnormal lung lobation (HP:0002101)1.81028778
109Leiomyosarcoma (HP:0100243)1.81025742
110Uterine leiomyosarcoma (HP:0002891)1.81025742
111Abnormality of the distal phalanx of the thumb (HP:0009617)1.80907667
112Missing ribs (HP:0000921)1.80304151
113Transitional cell carcinoma of the bladder (HP:0006740)1.78753345
114Partial agenesis of the corpus callosum (HP:0001338)1.78355486
115Sloping forehead (HP:0000340)1.76810509
116Intestinal atresia (HP:0011100)1.76732011
117Sandal gap (HP:0001852)1.76421891
118Bifid tongue (HP:0010297)1.75831267
119Abnormality of the duodenum (HP:0002246)1.75645159
120Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.75628238
121Hypopigmentation of the fundus (HP:0007894)1.74533512
122Cutaneous finger syndactyly (HP:0010554)1.74280818
123Small hand (HP:0200055)1.74059514
124Low anterior hairline (HP:0000294)1.73698075
125Preauricular skin tag (HP:0000384)1.72873196
126Cafe-au-lait spot (HP:0000957)1.70695873
127Birth length less than 3rd percentile (HP:0003561)1.70107987
128Hypoplastic ischia (HP:0003175)1.69918393
129Smooth philtrum (HP:0000319)1.69637127
130Poor coordination (HP:0002370)1.69375187
131Biliary tract neoplasm (HP:0100574)1.69108258
132True hermaphroditism (HP:0010459)1.67458372
133Broad palm (HP:0001169)1.67193299
134Embryonal neoplasm (HP:0002898)1.66976904
135Broad phalanges of the hand (HP:0009768)1.66165077
136Narrow palate (HP:0000189)1.65719751
137Gonadotropin excess (HP:0000837)1.65160131
138Generalized hypopigmentation of hair (HP:0011358)1.65150929
139Cupped ear (HP:0000378)1.64962057
140Excessive salivation (HP:0003781)1.64865218
141Broad-based gait (HP:0002136)1.64756777
142Chorioretinal atrophy (HP:0000533)1.64442515
143Atresia of the external auditory canal (HP:0000413)1.63526456
144Selective tooth agenesis (HP:0001592)1.63361908
145Obsessive-compulsive behavior (HP:0000722)1.62952205
146Spinal muscular atrophy (HP:0007269)1.62832185
147Midline defect of the nose (HP:0004122)1.62033865
148Enlarged kidneys (HP:0000105)1.61859232
149Cystic hygroma (HP:0000476)1.61816463
150Hypoplastic iliac wings (HP:0002866)1.61795277
151Abnormality of the 1st metacarpal (HP:0010009)1.61604296
152Hypospadias (HP:0000047)1.60364225
153Neonatal hypoglycemia (HP:0001998)1.60060836
154Clubbing of toes (HP:0100760)1.59649118
155Tapered finger (HP:0001182)1.59628211
156Progressive inability to walk (HP:0002505)1.57932852

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK127.78892696
2CDC73.15269663
3LATS12.82075753
4BMPR1B2.75831907
5BRD42.66043378
6TTK2.60620313
7CAMK1D2.18758515
8SRPK12.10269526
9TAOK31.93344241
10AKT31.91858722
11ZAK1.88005962
12MAP3K41.69205283
13CHEK21.66240107
14NEK21.65871545
15CDK71.65682522
16CASK1.63634892
17EIF2AK31.63545152
18FGFR31.61913714
19ATR1.61235563
20NLK1.60569177
21CAMK1G1.58967155
22CHEK11.51634183
23EPHA21.51572774
24STK391.49219119
25ATM1.44998423
26CSF1R1.39928538
27PLK11.36445082
28MKNK21.36052274
29STK31.34198979
30WNK11.32213881
31WEE11.30216544
32WNK31.29142516
33FLT31.28580813
34RPS6KB21.25322542
35STK101.25203823
36TNIK1.17677600
37MKNK11.17440128
38PLK31.17131754
39GRK11.15128627
40MTOR1.14404471
41FRK1.12743858
42MAPK71.07414158
43ACVR1B1.07160433
44PASK1.06931311
45PLK21.03708729
46TEC1.02663938
47CDK41.02150820
48CDK21.01057450
49TSSK61.01008387
50AURKB1.00273503
51TAF10.99607034
52ALK0.99458802
53TRPM70.99071403
54CAMK40.98086490
55PNCK0.97795348
56MAPK130.97490774
57TGFBR20.94504067
58STK40.93274887
59CDK90.92690051
60ADRBK20.91524000
61GRK60.90613143
62PBK0.88303226
63CHUK0.87153812
64CDK10.86092125
65FGFR20.85190234
66TYRO30.85089044
67CDK60.83129376
68OXSR10.82487603
69MELK0.82318022
70GRK50.81935340
71SGK4940.81916365
72SGK2230.81916365
73SGK20.81757608
74NUAK10.80514229
75EIF2AK20.80475821
76STK38L0.80195442
77MAP3K100.79695848
78CSNK1G10.78035255
79HIPK20.77652665
80MAP4K20.74536827
81NEK90.74535576
82OBSCN0.72878405
83MAPK140.72141400
84CSNK1D0.72084199
85SGK30.71793383
86TGFBR10.71013504
87YES10.70577497
88SCYL20.69560291
89MARK20.68509349
90EEF2K0.68052497
91NEK60.67757780
92WNK40.66056370
93PIM10.66007573
94PIK3CG0.65635031
95SGK10.63215881
96PDGFRA0.62977527
97PDGFRB0.62708272
98PRKDC0.62563996
99BRSK20.61603589
100GSK3B0.60450608
101MAPK100.58990416
102MATK0.58781415
103TLK10.57106112
104FGFR10.56835016
105MAPK10.56699496
106PRKAA20.56507466
107PIK3CA0.54068787
108AKT10.53859915
109CSNK1E0.53739363
110AKT20.48985567
111STK240.48857937
112RPS6KA50.48530478
113MAP3K20.48473943
114DYRK30.47751776
115ICK0.47695558
116ERBB30.46029680
117MAP3K70.44205246
118FER0.43576425
119STK110.42683135
120RPS6KB10.42199785
121RIPK10.42176688
122MAPK80.40553014
123CDK80.40151103
124INSRR0.40092701
125CSNK1A1L0.39711358
126VRK10.38523324
127MAP3K80.37459564
128PLK40.36955194
129NEK10.36034671
130LATS20.34860400
131CDC42BPA0.32869211
132MARK30.31893541
133CDK30.31852753
134PRKAA10.31695940

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.17187760
2Fanconi anemia pathway_Homo sapiens_hsa034602.63153009
3Mismatch repair_Homo sapiens_hsa034302.56802170
4mRNA surveillance pathway_Homo sapiens_hsa030152.36935878
5Cell cycle_Homo sapiens_hsa041102.36273198
6RNA transport_Homo sapiens_hsa030132.35204473
7Non-homologous end-joining_Homo sapiens_hsa034502.34016845
8Homologous recombination_Homo sapiens_hsa034402.07520658
9DNA replication_Homo sapiens_hsa030302.04867786
10RNA degradation_Homo sapiens_hsa030181.87083935
11One carbon pool by folate_Homo sapiens_hsa006701.78744091
12Spliceosome_Homo sapiens_hsa030401.75428078
13MicroRNAs in cancer_Homo sapiens_hsa052061.72725682
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.71209668
15Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.70576390
16Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.65934379
17Transcriptional misregulation in cancer_Homo sapiens_hsa052021.60696943
18Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.57885469
19Systemic lupus erythematosus_Homo sapiens_hsa053221.49492912
20Lysine degradation_Homo sapiens_hsa003101.47692191
21p53 signaling pathway_Homo sapiens_hsa041151.44765317
22Basal transcription factors_Homo sapiens_hsa030221.43350118
23Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.40910022
24Basal cell carcinoma_Homo sapiens_hsa052171.40782202
25Nucleotide excision repair_Homo sapiens_hsa034201.40333172
26mTOR signaling pathway_Homo sapiens_hsa041501.36864147
27Adherens junction_Homo sapiens_hsa045201.33450772
28Base excision repair_Homo sapiens_hsa034101.28978292
29Fatty acid biosynthesis_Homo sapiens_hsa000611.28893797
30Viral carcinogenesis_Homo sapiens_hsa052031.26128189
31Nitrogen metabolism_Homo sapiens_hsa009101.21716865
32Herpes simplex infection_Homo sapiens_hsa051681.19548391
33Thyroid hormone signaling pathway_Homo sapiens_hsa049191.13078907
34Small cell lung cancer_Homo sapiens_hsa052221.11780613
35TGF-beta signaling pathway_Homo sapiens_hsa043501.10922241
36Circadian rhythm_Homo sapiens_hsa047101.09909879
37Thyroid cancer_Homo sapiens_hsa052161.09149114
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.08499489
39HTLV-I infection_Homo sapiens_hsa051661.08210022
40Hippo signaling pathway_Homo sapiens_hsa043901.06957058
41NF-kappa B signaling pathway_Homo sapiens_hsa040641.06550753
42Prostate cancer_Homo sapiens_hsa052151.03324325
43Taste transduction_Homo sapiens_hsa047421.02471438
44Colorectal cancer_Homo sapiens_hsa052101.00271305
45Ether lipid metabolism_Homo sapiens_hsa005650.99077440
46Notch signaling pathway_Homo sapiens_hsa043300.97762994
47Inositol phosphate metabolism_Homo sapiens_hsa005620.97706980
48Wnt signaling pathway_Homo sapiens_hsa043100.97354915
49Pathways in cancer_Homo sapiens_hsa052000.96005310
50Hedgehog signaling pathway_Homo sapiens_hsa043400.93300695
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.92699414
52Nicotine addiction_Homo sapiens_hsa050330.90924684
53Phosphatidylinositol signaling system_Homo sapiens_hsa040700.90878621
54Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.90151379
55Proteoglycans in cancer_Homo sapiens_hsa052050.87044660
56Alcoholism_Homo sapiens_hsa050340.84898360
57Chronic myeloid leukemia_Homo sapiens_hsa052200.84850483
58Propanoate metabolism_Homo sapiens_hsa006400.84197483
59Maturity onset diabetes of the young_Homo sapiens_hsa049500.83591947
60ABC transporters_Homo sapiens_hsa020100.81299105
61Dorso-ventral axis formation_Homo sapiens_hsa043200.80058010
62Endometrial cancer_Homo sapiens_hsa052130.79881211
63Oocyte meiosis_Homo sapiens_hsa041140.79624329
64RNA polymerase_Homo sapiens_hsa030200.77931930
65Non-small cell lung cancer_Homo sapiens_hsa052230.77354923
66Antigen processing and presentation_Homo sapiens_hsa046120.74681256
67Olfactory transduction_Homo sapiens_hsa047400.72194362
68Vitamin B6 metabolism_Homo sapiens_hsa007500.71866909
69FoxO signaling pathway_Homo sapiens_hsa040680.70091393
70Pancreatic cancer_Homo sapiens_hsa052120.69584543
71Acute myeloid leukemia_Homo sapiens_hsa052210.68984638
72Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.68205924
73Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.67460669
74ECM-receptor interaction_Homo sapiens_hsa045120.66517845
75Epstein-Barr virus infection_Homo sapiens_hsa051690.66169409
76Focal adhesion_Homo sapiens_hsa045100.65438969
77Purine metabolism_Homo sapiens_hsa002300.64582604
78B cell receptor signaling pathway_Homo sapiens_hsa046620.64582555
79Long-term depression_Homo sapiens_hsa047300.64462268
80Butanoate metabolism_Homo sapiens_hsa006500.64236808
81T cell receptor signaling pathway_Homo sapiens_hsa046600.63957512
82Primary immunodeficiency_Homo sapiens_hsa053400.63368540
83Regulation of actin cytoskeleton_Homo sapiens_hsa048100.62692276
84PI3K-Akt signaling pathway_Homo sapiens_hsa041510.62380611
85Longevity regulating pathway - mammal_Homo sapiens_hsa042110.61708351
86Central carbon metabolism in cancer_Homo sapiens_hsa052300.61418924
87Linoleic acid metabolism_Homo sapiens_hsa005910.61405767
88Hepatitis B_Homo sapiens_hsa051610.60910712
89Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59503068
90Influenza A_Homo sapiens_hsa051640.59059942
91Jak-STAT signaling pathway_Homo sapiens_hsa046300.58281716
92Type II diabetes mellitus_Homo sapiens_hsa049300.58198907
93Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.56885723
94Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.56010330
95Choline metabolism in cancer_Homo sapiens_hsa052310.55738520
96RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.55049689
97alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.54931178
98Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.54214271
99Glutamatergic synapse_Homo sapiens_hsa047240.54148332
100Steroid biosynthesis_Homo sapiens_hsa001000.53431750
101Thyroid hormone synthesis_Homo sapiens_hsa049180.52506955
102Tight junction_Homo sapiens_hsa045300.52441538
103Renin-angiotensin system_Homo sapiens_hsa046140.52420201
104Measles_Homo sapiens_hsa051620.52317498
105NOD-like receptor signaling pathway_Homo sapiens_hsa046210.51260138
106Melanoma_Homo sapiens_hsa052180.51250159
107Apoptosis_Homo sapiens_hsa042100.50376317
108Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50257494
109Hematopoietic cell lineage_Homo sapiens_hsa046400.50132308
110MAPK signaling pathway_Homo sapiens_hsa040100.50054276
111Rap1 signaling pathway_Homo sapiens_hsa040150.49922320
112Phototransduction_Homo sapiens_hsa047440.48985040
113ErbB signaling pathway_Homo sapiens_hsa040120.48956877
114cGMP-PKG signaling pathway_Homo sapiens_hsa040220.48796998
115Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.48182606
116Leukocyte transendothelial migration_Homo sapiens_hsa046700.46899298
117Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.45142665
118Viral myocarditis_Homo sapiens_hsa054160.45070157
119Calcium signaling pathway_Homo sapiens_hsa040200.44855511
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.44554703
121Prolactin signaling pathway_Homo sapiens_hsa049170.44270489
122Vascular smooth muscle contraction_Homo sapiens_hsa042700.44170581
123Glycerolipid metabolism_Homo sapiens_hsa005610.42603141
124Glioma_Homo sapiens_hsa052140.41882961
125Phospholipase D signaling pathway_Homo sapiens_hsa040720.41520855
126AMPK signaling pathway_Homo sapiens_hsa041520.40715446
127Morphine addiction_Homo sapiens_hsa050320.40382484
128Pyrimidine metabolism_Homo sapiens_hsa002400.40300847
129Insulin resistance_Homo sapiens_hsa049310.40166656
130Toxoplasmosis_Homo sapiens_hsa051450.39598757
131Neurotrophin signaling pathway_Homo sapiens_hsa047220.39318624
132HIF-1 signaling pathway_Homo sapiens_hsa040660.39126446
133Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.38896171
134TNF signaling pathway_Homo sapiens_hsa046680.38705252
135Selenocompound metabolism_Homo sapiens_hsa004500.38055465
136Cholinergic synapse_Homo sapiens_hsa047250.37436613
137Serotonergic synapse_Homo sapiens_hsa047260.37184361
138Ovarian steroidogenesis_Homo sapiens_hsa049130.36424723

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