MGEA5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)4.61071599
2layer formation in cerebral cortex (GO:0021819)4.54944282
3locomotory exploration behavior (GO:0035641)4.41178583
4regulation of short-term neuronal synaptic plasticity (GO:0048172)4.37988747
5synaptic vesicle maturation (GO:0016188)4.31653718
6phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.93755760
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.93650778
8histone H3-K4 trimethylation (GO:0080182)3.89981783
9dendritic spine morphogenesis (GO:0060997)3.77973021
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.77258135
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.61476910
12negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.59164312
13negative regulation of translation, ncRNA-mediated (GO:0040033)3.59164312
14regulation of translation, ncRNA-mediated (GO:0045974)3.59164312
15presynaptic membrane organization (GO:0097090)3.54069168
16negative regulation of cell killing (GO:0031342)3.51891575
17negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.51891575
18exploration behavior (GO:0035640)3.51791043
19establishment of nucleus localization (GO:0040023)3.49213227
20nucleobase catabolic process (GO:0046113)3.48253953
21regulation of synaptic vesicle exocytosis (GO:2000300)3.41072096
22regulation of glutamate receptor signaling pathway (GO:1900449)3.40956023
23histone H3-K36 demethylation (GO:0070544)3.39168998
24synaptic vesicle docking involved in exocytosis (GO:0016081)3.38636034
25histone H3-K9 demethylation (GO:0033169)3.38453002
26nerve growth factor signaling pathway (GO:0038180)3.36783217
27glutamate secretion (GO:0014047)3.35181581
28dendrite morphogenesis (GO:0048813)3.33488628
29cerebral cortex radially oriented cell migration (GO:0021799)3.33100024
30vocalization behavior (GO:0071625)3.28645526
31protein localization to synapse (GO:0035418)3.28510634
32neural tube formation (GO:0001841)3.26748644
33synaptic vesicle exocytosis (GO:0016079)3.24366114
34histone lysine demethylation (GO:0070076)3.22144364
35monoubiquitinated protein deubiquitination (GO:0035520)3.21526731
36vesicle transport along microtubule (GO:0047496)3.20004024
37peptidyl-lysine trimethylation (GO:0018023)3.17793659
38olfactory bulb development (GO:0021772)3.17359803
39regulation of dendritic spine morphogenesis (GO:0061001)3.14785254
40cerebellar Purkinje cell differentiation (GO:0021702)3.14497509
41cytoplasmic mRNA processing body assembly (GO:0033962)3.13160051
42neuron cell-cell adhesion (GO:0007158)3.11286931
43activated T cell proliferation (GO:0050798)3.09837439
44central nervous system projection neuron axonogenesis (GO:0021952)3.09383557
45axonal fasciculation (GO:0007413)3.09375396
46clathrin coat assembly (GO:0048268)3.08469113
47histone demethylation (GO:0016577)3.07932027
48cell migration in hindbrain (GO:0021535)3.07204481
49negative regulation of neurotransmitter secretion (GO:0046929)3.05918499
50ionotropic glutamate receptor signaling pathway (GO:0035235)3.04134950
51histone H3-K9 modification (GO:0061647)2.99093745
52neuron recognition (GO:0008038)2.97564076
53regulation of long-term neuronal synaptic plasticity (GO:0048169)2.96732832
54regulation of synapse structural plasticity (GO:0051823)2.94805843
55histone H3-K9 methylation (GO:0051567)2.94231277
56regulation of neuronal synaptic plasticity (GO:0048168)2.91193063
57organelle transport along microtubule (GO:0072384)2.86695363
58glial cell proliferation (GO:0014009)2.83088025
59cytoskeletal anchoring at plasma membrane (GO:0007016)2.79632493
60activation of protein kinase A activity (GO:0034199)2.78929947
61G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.78703767
62cerebellar granule cell differentiation (GO:0021707)2.77512688
63regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.77399559
64prepulse inhibition (GO:0060134)2.77368715
65proline transport (GO:0015824)2.76624482
66protein dealkylation (GO:0008214)2.76196693
67protein demethylation (GO:0006482)2.76196693
68forebrain neuron differentiation (GO:0021879)2.75465501
69regulation of synaptic vesicle transport (GO:1902803)2.75029759
70mRNA splice site selection (GO:0006376)2.73912064
71neurotransmitter secretion (GO:0007269)2.73259575
72regulation of NFAT protein import into nucleus (GO:0051532)2.73191657
73pre-miRNA processing (GO:0031054)2.71933741
74histone H3-K4 methylation (GO:0051568)2.71748541
75neuromuscular process controlling balance (GO:0050885)2.68610196
76glutamate receptor signaling pathway (GO:0007215)2.67989836
77regulation of clathrin-mediated endocytosis (GO:2000369)2.67327822
78signal complex assembly (GO:0007172)2.66171563
79axon extension (GO:0048675)2.64043007
80regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.64033468
81positive regulation of synapse maturation (GO:0090129)2.63504198
82synaptic transmission, glutamatergic (GO:0035249)2.61899846
83regulation of ARF protein signal transduction (GO:0032012)2.61466955
84stress granule assembly (GO:0034063)2.59283573
85negative regulation of neurotransmitter transport (GO:0051589)2.59050148
86dendritic spine organization (GO:0097061)2.58788006
87regulation of pigment cell differentiation (GO:0050932)2.57136639
88regulation of excitatory postsynaptic membrane potential (GO:0060079)2.56505941
89histone H4-K16 acetylation (GO:0043984)2.56296131
90protein targeting to Golgi (GO:0000042)2.55851440
91positive regulation of dendritic spine morphogenesis (GO:0061003)2.55504493
92establishment of mitochondrion localization (GO:0051654)2.55374543
93establishment of protein localization to Golgi (GO:0072600)2.55078671
94centrosome localization (GO:0051642)2.54750784
95regulation of dendritic spine development (GO:0060998)2.54533650
96peptidyl-threonine phosphorylation (GO:0018107)2.54225071
97central nervous system neuron axonogenesis (GO:0021955)2.53430522
98long-term memory (GO:0007616)2.53228721
99peptidyl-lysine methylation (GO:0018022)2.53066800
100neuron-neuron synaptic transmission (GO:0007270)2.52876479
101positive regulation of developmental pigmentation (GO:0048087)2.52517680
102histone lysine methylation (GO:0034968)2.51421168
103regulation of RNA export from nucleus (GO:0046831)2.49173603
104response to histamine (GO:0034776)2.48651117
105neurotransmitter-gated ion channel clustering (GO:0072578)2.48123649
106positive T cell selection (GO:0043368)2.47878538
107long-term synaptic potentiation (GO:0060291)2.46780975
108regulation of postsynaptic membrane potential (GO:0060078)2.46192927
109synaptic vesicle endocytosis (GO:0048488)2.45177281
110regulation of B cell receptor signaling pathway (GO:0050855)2.44970102
111negative regulation of immunoglobulin mediated immune response (GO:0002890)2.43142427
112negative regulation of B cell mediated immunity (GO:0002713)2.43142427
113postsynaptic membrane organization (GO:0001941)2.42569888
114negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.42541858
115mitotic sister chromatid cohesion (GO:0007064)2.42207498
116regulation of Rac protein signal transduction (GO:0035020)2.41504433
117limb bud formation (GO:0060174)2.41436656
118microtubule nucleation (GO:0007020)2.41144480
119innervation (GO:0060384)2.41106784
120interkinetic nuclear migration (GO:0022027)2.40356462
121peptidyl-threonine modification (GO:0018210)2.40214132
122neuronal stem cell maintenance (GO:0097150)2.40207959
123neuron projection extension (GO:1990138)2.38202809
124auditory behavior (GO:0031223)2.37859085
125regulation of synaptic plasticity (GO:0048167)2.37483730
126neuronal ion channel clustering (GO:0045161)2.37282857
127retrograde transport, vesicle recycling within Golgi (GO:0000301)2.36723798
128sodium ion export (GO:0071436)2.36594136
129cellular potassium ion homeostasis (GO:0030007)2.35543836
130negative regulation of histone methylation (GO:0031061)2.33089864
131establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.31120175
132mitochondrion transport along microtubule (GO:0047497)2.31120175
133response to nerve growth factor (GO:1990089)2.28525023
134cellular response to nerve growth factor stimulus (GO:1990090)2.28525023
135nucleus localization (GO:0051647)2.28388180
136suckling behavior (GO:0001967)2.28155794
137cell differentiation in hindbrain (GO:0021533)2.28101498
138mating behavior (GO:0007617)2.26691736
139positive regulation of membrane potential (GO:0045838)2.26687315
140synapse assembly (GO:0007416)2.26265286
141negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.25591324
142microtubule anchoring (GO:0034453)2.25305965
143presynaptic membrane assembly (GO:0097105)2.24931901
144behavioral defense response (GO:0002209)2.24899265
145behavioral fear response (GO:0001662)2.24899265
146positive regulation of axon extension (GO:0045773)2.24722098
147regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.24173907
148dopamine receptor signaling pathway (GO:0007212)2.23426141
149cerebellum development (GO:0021549)2.23215921
150positive regulation of gamma-delta T cell activation (GO:0046645)2.23138967
151regulation of neurotransmitter secretion (GO:0046928)2.22149468
152neuron projection morphogenesis (GO:0048812)2.22033592
153Golgi to endosome transport (GO:0006895)2.20827138
154cerebral cortex cell migration (GO:0021795)2.20131844
155dendrite development (GO:0016358)2.17897901
156negative thymic T cell selection (GO:0045060)2.17043165
157tachykinin receptor signaling pathway (GO:0007217)2.17019092

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.85365413
2ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.64064360
3GBX2_23144817_ChIP-Seq_PC3_Human2.34637768
4TAF15_26573619_Chip-Seq_HEK293_Human2.33440957
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.31853573
6RARB_27405468_Chip-Seq_BRAIN_Mouse2.25201480
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.15943288
8SALL1_21062744_ChIP-ChIP_HESCs_Human2.12627318
9DROSHA_22980978_ChIP-Seq_HELA_Human2.11936081
10TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.02641841
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.02461696
12JARID2_20064375_ChIP-Seq_MESCs_Mouse1.97047319
13IGF1R_20145208_ChIP-Seq_DFB_Human1.96792590
14SMAD_19615063_ChIP-ChIP_OVARY_Human1.95396068
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.89995353
16SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.89872131
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.89080956
18AR_21572438_ChIP-Seq_LNCaP_Human1.87486499
19CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.86878991
20SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.83589760
21ZNF217_24962896_ChIP-Seq_MCF-7_Human1.83487355
22EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.81160842
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.80664942
24* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.78558955
25RBPJ_22232070_ChIP-Seq_NCS_Mouse1.77432923
26RNF2_18974828_ChIP-Seq_MESCs_Mouse1.71970920
27EZH2_18974828_ChIP-Seq_MESCs_Mouse1.71970920
28VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.68105554
29AHR_22903824_ChIP-Seq_MCF-7_Human1.67503032
30REST_21632747_ChIP-Seq_MESCs_Mouse1.64497086
31MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.63383027
32ARNT_22903824_ChIP-Seq_MCF-7_Human1.63062805
33WT1_19549856_ChIP-ChIP_CCG9911_Human1.62318430
34TP53_16413492_ChIP-PET_HCT116_Human1.60919655
35MTF2_20144788_ChIP-Seq_MESCs_Mouse1.60667259
36SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.60369021
37RNF2_27304074_Chip-Seq_ESCs_Mouse1.60325618
38EZH2_27304074_Chip-Seq_ESCs_Mouse1.52666447
39SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.52143883
40STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.51945253
41CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.50701836
42SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.50110041
43GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.47776801
44SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.47218580
45ZFP281_27345836_Chip-Seq_ESCs_Mouse1.46642585
46DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.46018038
47SMAD4_21799915_ChIP-Seq_A2780_Human1.45235975
48EGR1_19374776_ChIP-ChIP_THP-1_Human1.43871731
49JARID2_20075857_ChIP-Seq_MESCs_Mouse1.43485431
50SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.42386693
51KDM2B_26808549_Chip-Seq_K562_Human1.40758712
52TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36760256
53SOX2_21211035_ChIP-Seq_LN229_Gbm1.34753739
54STAT3_23295773_ChIP-Seq_U87_Human1.33175026
55YAP1_20516196_ChIP-Seq_MESCs_Mouse1.32802723
56* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.31909405
57AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.31496922
58EZH2_27294783_Chip-Seq_ESCs_Mouse1.30626576
59* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.27855123
60RNF2_27304074_Chip-Seq_NSC_Mouse1.27727224
61SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.27715868
62PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.27412110
63* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.26819367
64TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.26775823
65SUZ12_27294783_Chip-Seq_ESCs_Mouse1.26518726
66AR_19668381_ChIP-Seq_PC3_Human1.26242125
67CTBP2_25329375_ChIP-Seq_LNCAP_Human1.24405890
68TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.23509134
69CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.23103975
70SMAD3_21741376_ChIP-Seq_EPCs_Human1.22294434
71* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.22293903
72SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.22087486
73EWS_26573619_Chip-Seq_HEK293_Human1.22020969
74RING1B_27294783_Chip-Seq_NPCs_Mouse1.21103596
75NANOG_18555785_Chip-Seq_ESCs_Mouse1.20913261
76TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.20809684
77NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.19979309
78FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.19970231
79ESR1_20079471_ChIP-ChIP_T-47D_Human1.19611802
80* KDM2B_26808549_Chip-Seq_JURKAT_Human1.18695526
81TCF4_23295773_ChIP-Seq_U87_Human1.18461911
82NR3C1_23031785_ChIP-Seq_PC12_Mouse1.18123999
83KDM2B_26808549_Chip-Seq_SUP-B15_Human1.17831374
84RUNX2_22187159_ChIP-Seq_PCA_Human1.17549985
85* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.17222984
86REST_18959480_ChIP-ChIP_MESCs_Mouse1.17150744
87CTBP1_25329375_ChIP-Seq_LNCAP_Human1.16967046
88UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16817160
89P300_19829295_ChIP-Seq_ESCs_Human1.16793190
90TP63_19390658_ChIP-ChIP_HaCaT_Human1.16071699
91TCF4_18268006_ChIP-ChIP_LS174T_Human1.12966659
92KDM2B_26808549_Chip-Seq_REH_Human1.12826450
93PIAS1_25552417_ChIP-Seq_VCAP_Human1.12718286
94LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12454629
95* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.12374197
96* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.12307785
97CBX2_27304074_Chip-Seq_ESCs_Mouse1.12291293
98POU3F2_20337985_ChIP-ChIP_501MEL_Human1.11740434
99TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11263558
100ZNF274_21170338_ChIP-Seq_K562_Hela1.10842050
101* KDM2B_26808549_Chip-Seq_DND41_Human1.10662669
102EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.10481662
103FUS_26573619_Chip-Seq_HEK293_Human1.10320290
104AR_25329375_ChIP-Seq_VCAP_Human1.10026283
105PRDM14_20953172_ChIP-Seq_ESCs_Human1.09457332
106FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.09241235
107* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.08923246
108FLI1_21867929_ChIP-Seq_TH2_Mouse1.08786168
109EED_16625203_ChIP-ChIP_MESCs_Mouse1.08724540
110RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.08611499
111PKCTHETA_26484144_Chip-Seq_BREAST_Human1.07883827
112HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.07864363
113FLI1_27457419_Chip-Seq_LIVER_Mouse1.07279374
114* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.06875491
115PCGF2_27294783_Chip-Seq_NPCs_Mouse1.06859139
116* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06678406
117IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05962804
118CBP_20019798_ChIP-Seq_JUKART_Human1.05962804
119KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.05805571
120RXR_22108803_ChIP-Seq_LS180_Human1.04897792
121ER_23166858_ChIP-Seq_MCF-7_Human1.04743018
122STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.04573217
123POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.03663902
124TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03663902
125CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03516559
126CDX2_19796622_ChIP-Seq_MESCs_Mouse1.03039606
127RUNX_20019798_ChIP-Seq_JUKART_Human1.02639296
128BCAT_22108803_ChIP-Seq_LS180_Human1.02548865
129RING1B_27294783_Chip-Seq_ESCs_Mouse1.02121510
130TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.02107964
131P53_22127205_ChIP-Seq_FIBROBLAST_Human1.01514067
132RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.01338772
133SMAD3_21741376_ChIP-Seq_ESCs_Human1.00067712
134TOP2B_26459242_ChIP-Seq_MCF-7_Human0.99891291
135NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99650370
136* ISL1_27105846_Chip-Seq_CPCs_Mouse0.99115092

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.60216045
2MP0010234_abnormal_vibrissa_follicle3.65165971
3MP0000569_abnormal_digit_pigmentation3.64990580
4MP0004270_analgesia3.42411624
5MP0003635_abnormal_synaptic_transmissio3.30658522
6MP0008057_abnormal_DNA_replication2.92442252
7MP0003880_abnormal_central_pattern2.90074724
8MP0003787_abnormal_imprinting2.82528957
9MP0002063_abnormal_learning/memory/cond2.74874185
10MP0009780_abnormal_chondrocyte_physiolo2.53033951
11MP0000778_abnormal_nervous_system2.36153881
12MP0009745_abnormal_behavioral_response2.35969198
13MP0002064_seizures2.07255769
14MP0002572_abnormal_emotion/affect_behav2.00796861
15MP0001486_abnormal_startle_reflex1.95819342
16MP0008961_abnormal_basal_metabolism1.92049478
17MP0001188_hyperpigmentation1.80522931
18MP0004885_abnormal_endolymph1.78149125
19MP0004811_abnormal_neuron_physiology1.77984834
20MP0005423_abnormal_somatic_nervous1.73515092
21MP0002734_abnormal_mechanical_nocicepti1.71889865
22MP0005076_abnormal_cell_differentiation1.70223545
23MP0000537_abnormal_urethra_morphology1.69895163
24MP0009046_muscle_twitch1.68692727
25MP0001968_abnormal_touch/_nociception1.63235666
26MP0002184_abnormal_innervation1.62781330
27MP0006292_abnormal_olfactory_placode1.62297414
28MP0002822_catalepsy1.59839900
29MP0004858_abnormal_nervous_system1.57686383
30MP0010352_gastrointestinal_tract_polyps1.54917848
31MP0008569_lethality_at_weaning1.51151707
32MP0005623_abnormal_meninges_morphology1.50403988
33MP0003890_abnormal_embryonic-extraembry1.47430320
34MP0002909_abnormal_adrenal_gland1.46035450
35MP0000955_abnormal_spinal_cord1.45639186
36MP0001529_abnormal_vocalization1.44466976
37MP0002557_abnormal_social/conspecific_i1.42092972
38MP0005386_behavior/neurological_phenoty1.42087440
39MP0004924_abnormal_behavior1.42087440
40MP0010678_abnormal_skin_adnexa1.38445386
41MP0005187_abnormal_penis_morphology1.36832044
42MP0003221_abnormal_cardiomyocyte_apopto1.34555376
43MP0001440_abnormal_grooming_behavior1.34356159
44MP0002009_preneoplasia1.34298112
45MP0003121_genomic_imprinting1.33998314
46MP0002272_abnormal_nervous_system1.32401313
47MP0002067_abnormal_sensory_capabilities1.30858563
48MP0003690_abnormal_glial_cell1.30568888
49MP0002152_abnormal_brain_morphology1.29728412
50MP0002882_abnormal_neuron_morphology1.27663133
51MP0005367_renal/urinary_system_phenotyp1.21455338
52MP0000516_abnormal_urinary_system1.21455338
53MP0001501_abnormal_sleep_pattern1.20450236
54MP0001984_abnormal_olfaction1.18968592
55MP0003861_abnormal_nervous_system1.17528969
56MP0003763_abnormal_thymus_physiology1.16271242
57MP0001177_atelectasis1.13723840
58MP0001299_abnormal_eye_distance/1.13533101
59MP0004130_abnormal_muscle_cell1.11318608
60MP0005248_abnormal_Harderian_gland1.09882496
61MP0003567_abnormal_fetal_cardiomyocyte1.04361976
62MP0005409_darkened_coat_color1.04072779
63MP0002928_abnormal_bile_duct1.00391098
64MP0002733_abnormal_thermal_nociception0.99968695
65MP0002066_abnormal_motor_capabilities/c0.99713110
66MP0006276_abnormal_autonomic_nervous0.97873016
67MP0003633_abnormal_nervous_system0.97437224
68MP0001970_abnormal_pain_threshold0.96793567
69MP0003122_maternal_imprinting0.96789231
70MP0002233_abnormal_nose_morphology0.96659544
71MP0004742_abnormal_vestibular_system0.96179505
72MP0002751_abnormal_autonomic_nervous0.95647831
73MP0004883_abnormal_blood_vessel0.94420659
74MP0002736_abnormal_nociception_after0.91669475
75MP0002752_abnormal_somatic_nervous0.91624580
76MP0003938_abnormal_ear_development0.91392087
77MP0004142_abnormal_muscle_tone0.91273620
78MP0008260_abnormal_autophagy0.90993029
79MP0002735_abnormal_chemical_nociception0.90631821
80MP0001286_abnormal_eye_development0.89978852
81MP0003300_gastrointestinal_ulcer0.89443258
82MP0003631_nervous_system_phenotype0.88753343
83MP0004381_abnormal_hair_follicle0.88743139
84MP0003115_abnormal_respiratory_system0.88513230
85MP0000703_abnormal_thymus_morphology0.87355084
86MP0000631_abnormal_neuroendocrine_gland0.87188398
87MP0008995_early_reproductive_senescence0.86626324
88MP0008789_abnormal_olfactory_epithelium0.85911772
89MP0001502_abnormal_circadian_rhythm0.85564955
90MP0001348_abnormal_lacrimal_gland0.85299044
91MP0002133_abnormal_respiratory_system0.84707984
92MP0005388_respiratory_system_phenotype0.84707984
93MP0003329_amyloid_beta_deposits0.84443010
94MP0004197_abnormal_fetal_growth/weight/0.84208650
95MP0003632_abnormal_nervous_system0.83549487
96MP0003283_abnormal_digestive_organ0.82484994
97MP0008877_abnormal_DNA_methylation0.81453852
98MP0003634_abnormal_glial_cell0.80814639
99MP0003091_abnormal_cell_migration0.80753587
100MP0002084_abnormal_developmental_patter0.79664937
101MP0001849_ear_inflammation0.79044922
102MP0002081_perinatal_lethality0.78950430
103MP0000427_abnormal_hair_cycle0.77924888
104MP0001293_anophthalmia0.77073097
105MP0003045_fibrosis0.76410209
106MP0005174_abnormal_tail_pigmentation0.76241090
107MP0003303_peritoneal_inflammation0.76145206
108MP0004233_abnormal_muscle_weight0.75437273
109MP0002166_altered_tumor_susceptibility0.74320522
110MP0003123_paternal_imprinting0.74170397
111MP0003879_abnormal_hair_cell0.73521445
112MP0004510_myositis0.72900749
113MP0009703_decreased_birth_body0.72407446
114MP0002638_abnormal_pupillary_reflex0.71879809
115MP0000534_abnormal_ureter_morphology0.71714194
116MP0003935_abnormal_craniofacial_develop0.71366402
117MP0000733_abnormal_muscle_development0.70681716
118MP0008770_decreased_survivor_rate0.69960691
119MP0004085_abnormal_heartbeat0.69404607
120MP0001943_abnormal_respiration0.68962429
121MP0003119_abnormal_digestive_system0.67803853
122MP0003705_abnormal_hypodermis_morpholog0.67352853
123MP0005394_taste/olfaction_phenotype0.66699272
124MP0005499_abnormal_olfactory_system0.66699272
125MP0010769_abnormal_survival0.65976843
126MP0005646_abnormal_pituitary_gland0.65855035
127MP0003385_abnormal_body_wall0.62706865
128MP0010770_preweaning_lethality0.62474651
129MP0002082_postnatal_lethality0.62474651
130MP0010768_mortality/aging0.61972771
131MP0000428_abnormal_craniofacial_morphol0.61945057
132MP0002925_abnormal_cardiovascular_devel0.61788020
133MP0004484_altered_response_of0.61483835

Predicted human phenotypes

RankGene SetZ-score
1Focal seizures (HP:0007359)3.13514678
2Insidious onset (HP:0003587)3.07272652
3Termporal pattern (HP:0011008)3.07272652
4Macroorchidism (HP:0000053)3.03219380
5Genetic anticipation (HP:0003743)2.89847279
6Volvulus (HP:0002580)2.86933298
7Myokymia (HP:0002411)2.85033288
8Focal motor seizures (HP:0011153)2.81977482
9Abnormality of the lower motor neuron (HP:0002366)2.73564103
10Epileptic encephalopathy (HP:0200134)2.72304866
11Excessive salivation (HP:0003781)2.72132396
12Drooling (HP:0002307)2.72132396
13Inappropriate behavior (HP:0000719)2.70903561
14Urinary bladder sphincter dysfunction (HP:0002839)2.69559205
15Amyotrophic lateral sclerosis (HP:0007354)2.68660742
16Aqueductal stenosis (HP:0002410)2.62965593
17Urinary urgency (HP:0000012)2.60354239
18Abnormality of the corticospinal tract (HP:0002492)2.56784216
19Visual hallucinations (HP:0002367)2.55903496
20Progressive cerebellar ataxia (HP:0002073)2.52879706
21Action tremor (HP:0002345)2.50063513
22Astrocytoma (HP:0009592)2.48528138
23Abnormality of the astrocytes (HP:0100707)2.48528138
24Impaired vibration sensation in the lower limbs (HP:0002166)2.42299479
25Subacute progressive viral hepatitis (HP:0006572)2.40446889
26Febrile seizures (HP:0002373)2.40122722
27Papillary thyroid carcinoma (HP:0002895)2.39382102
28Broad-based gait (HP:0002136)2.38604310
29Hyperacusis (HP:0010780)2.37861479
30Curly hair (HP:0002212)2.32427998
31Ankle clonus (HP:0011448)2.26969577
32Supranuclear gaze palsy (HP:0000605)2.24464458
33Ankyloglossia (HP:0010296)2.24357680
34Atonic seizures (HP:0010819)2.23294864
35Abnormal hair whorl (HP:0010721)2.22083247
36Dysmetric saccades (HP:0000641)2.21424594
37Papilledema (HP:0001085)2.19405051
38Truncal obesity (HP:0001956)2.17179009
39Pointed chin (HP:0000307)2.13640671
40Tented upper lip vermilion (HP:0010804)2.13274917
41Obsessive-compulsive behavior (HP:0000722)2.10161289
42Impaired smooth pursuit (HP:0007772)2.09671321
43Abnormality of oral frenula (HP:0000190)2.09279413
44Heterotopia (HP:0002282)2.04979204
45Stomach cancer (HP:0012126)2.03631796
46Absence seizures (HP:0002121)1.99961450
47Neoplasm of the adrenal cortex (HP:0100641)1.99395775
48Insomnia (HP:0100785)1.98936920
49Short 4th metacarpal (HP:0010044)1.98441596
50Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.98441596
51Absent frontal sinuses (HP:0002688)1.98256165
52Chronic hepatic failure (HP:0100626)1.98114014
53Poor eye contact (HP:0000817)1.96985073
54Lower limb amyotrophy (HP:0007210)1.96286533
55Hypochromic microcytic anemia (HP:0004840)1.96002234
56Truncal ataxia (HP:0002078)1.95331325
57Cupped ear (HP:0000378)1.94909186
58Spastic gait (HP:0002064)1.94444278
59Abnormality of ocular smooth pursuit (HP:0000617)1.94175542
60Impaired social interactions (HP:0000735)1.94058056
61Abnormal social behavior (HP:0012433)1.94058056
62Dysdiadochokinesis (HP:0002075)1.94027766
63Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.92983956
64Narrow palate (HP:0000189)1.92909107
65Stereotypic behavior (HP:0000733)1.90779451
66Exotropia (HP:0000577)1.90495194
67Cystic hygroma (HP:0000476)1.90305495
68Hip dysplasia (HP:0001385)1.90212819
69Oligodactyly (hands) (HP:0001180)1.89609586
70Mutism (HP:0002300)1.88668179
71Postural instability (HP:0002172)1.88570606
72High anterior hairline (HP:0009890)1.87072093
73Vertebral arch anomaly (HP:0008438)1.86939718
74Depression (HP:0000716)1.86864712
75T lymphocytopenia (HP:0005403)1.86772926
76Large earlobe (HP:0009748)1.86566464
77Gaze-evoked nystagmus (HP:0000640)1.86515107
78Cerebral inclusion bodies (HP:0100314)1.86093495
79Transitional cell carcinoma of the bladder (HP:0006740)1.86086869
80Asymmetry of the thorax (HP:0001555)1.85834724
81Elfin facies (HP:0004428)1.85519139
82Protruding tongue (HP:0010808)1.85403180
83Lower limb muscle weakness (HP:0007340)1.84450118
84Tubulointerstitial nephritis (HP:0001970)1.83828194
85Amblyopia (HP:0000646)1.83675489
86Sacral dimple (HP:0000960)1.83569629
87Shoulder girdle muscle weakness (HP:0003547)1.83067513
88Abnormality of binocular vision (HP:0011514)1.83053510
89Diplopia (HP:0000651)1.83053510
90Hyperventilation (HP:0002883)1.79741412
91Thickened helices (HP:0000391)1.78027549
92Vitreoretinal degeneration (HP:0000655)1.76903162
93Overriding aorta (HP:0002623)1.76393740
94Tapered finger (HP:0001182)1.76178987
95Deep palmar crease (HP:0006191)1.76176604
96Basal cell carcinoma (HP:0002671)1.75926949
97Gait imbalance (HP:0002141)1.75553914
98Open mouth (HP:0000194)1.75116992
99Widely spaced teeth (HP:0000687)1.75108884
100Poor coordination (HP:0002370)1.74240710
101Absent speech (HP:0001344)1.74238644
102Dialeptic seizures (HP:0011146)1.74145502
103Intellectual disability, moderate (HP:0002342)1.73472275
104Hematochezia (HP:0002573)1.73413324
105Apathy (HP:0000741)1.72518420
106Bladder carcinoma (HP:0002862)1.71863285
107Bladder neoplasm (HP:0009725)1.71863285
108Abnormality of the fingertips (HP:0001211)1.71327417
109Lower limb asymmetry (HP:0100559)1.70422137
110Abnormality of salivation (HP:0100755)1.69354804
111Generalized tonic-clonic seizures (HP:0002069)1.69293123
112Deeply set eye (HP:0000490)1.69257030
113Ependymoma (HP:0002888)1.69192661
114Abnormality of incisor morphology (HP:0011063)1.68802446
115Long clavicles (HP:0000890)1.67914498
116Megalencephaly (HP:0001355)1.67636678
117Intestinal atresia (HP:0011100)1.67345782
118Intention tremor (HP:0002080)1.67160834
119Neoplasm of the heart (HP:0100544)1.67152717
120Aplasia/Hypoplasia of the sternum (HP:0006714)1.65958302
121Glioma (HP:0009733)1.65512072
122Sporadic (HP:0003745)1.65157985
123Disinhibition (HP:0000734)1.64862833
124Abnormality of T cell number (HP:0011839)1.64342753
125Hyperthyroidism (HP:0000836)1.64179032
126Thick eyebrow (HP:0000574)1.64058811
127Thyroid carcinoma (HP:0002890)1.63655387
128Neonatal hypoglycemia (HP:0001998)1.63169698
129Hepatoblastoma (HP:0002884)1.63105380
130Resting tremor (HP:0002322)1.62747463
131Abnormality of the nasal septum (HP:0000419)1.62344162
132Increased nuchal translucency (HP:0010880)1.62325277
133Broad palm (HP:0001169)1.61910189
134Dysmetria (HP:0001310)1.61845455
135Shallow orbits (HP:0000586)1.61564429
136Genital tract atresia (HP:0001827)1.60686648
137Sandal gap (HP:0001852)1.59966141
138Gastroesophageal reflux (HP:0002020)1.58793519
139Abnormality of the antihelix (HP:0009738)1.58414818
140Cutaneous finger syndactyly (HP:0010554)1.56752238
141Thyroiditis (HP:0100646)1.55876494
142Cubitus valgus (HP:0002967)1.55769087
143Overgrowth (HP:0001548)1.55421758
144Obstructive sleep apnea (HP:0002870)1.54264241
145Hemiplegia (HP:0002301)1.54144214
146Neoplasm of the tracheobronchial system (HP:0100552)1.54016816
147Midline defect of the nose (HP:0004122)1.52991110
148Pulmonic stenosis (HP:0001642)1.52845845
149Impaired vibratory sensation (HP:0002495)1.52716464
150Cortical dysplasia (HP:0002539)1.52581235
151Abnormality of chromosome segregation (HP:0002916)1.50083178

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.07260069
2CASK3.40391175
3MAP3K93.30511526
4NTRK32.96821093
5MAP3K42.82557708
6EPHA42.73279486
7TNIK2.41961840
8FGFR22.17788713
9CAMKK12.00648834
10NTRK21.86325106
11SIK21.82691694
12KSR11.80040599
13YES11.71055865
14DAPK21.70142469
15MINK11.68491585
16CDK121.65449956
17PAK61.64590198
18PRKD31.61686725
19AKT31.56639583
20TYRO31.56385437
21FRK1.55265477
22KSR21.53605307
23LATS11.47810694
24MAPK131.43555345
25PNCK1.43375016
26CAMK1G1.42263992
27ALK1.40246873
28ERBB31.37634333
29MAP2K71.37584504
30MKNK21.34011416
31RET1.32105884
32CDK191.29173999
33MAP3K21.26482924
34MAP2K41.25168413
35PKN21.23938341
36PRKCH1.23194402
37CDK51.20040865
38CSNK1A1L1.19416628
39STK111.18067191
40SGK31.17236238
41NLK1.15968240
42CSNK1G21.14617197
43FGFR31.14258627
44SIK31.13596395
45UHMK11.13265842
46WNK31.09650253
47EEF2K1.08909231
48EPHA31.02812799
49PDGFRB1.02426767
50DMPK1.00865219
51SGK20.99495925
52RIPK40.98576864
53PDGFRA0.97556938
54PLK20.95381416
55STK380.90287735
56MAP3K100.90054651
57LATS20.89783795
58SGK10.87609329
59MARK20.86850084
60SCYL20.85459803
61DYRK20.81416181
62DYRK1B0.80444709
63CAMK1D0.79912514
64RIPK10.79897460
65WNK10.79484132
66CAMKK20.79471299
67SGK2230.78598462
68SGK4940.78598462
69MKNK10.78534350
70NTRK10.77401065
71DYRK30.76625543
72PRPF4B0.74756877
73MAP3K70.74233876
74FGFR10.73965529
75CAMK40.73452793
76ICK0.72695810
77BRD40.72104254
78PAK30.71600797
79PHKG10.70925285
80PHKG20.70925285
81FGR0.70858807
82TAOK10.70512716
83IRAK10.70003421
84DYRK1A0.68611066
85PTK60.67053439
86DAPK10.66811551
87CDK60.65813917
88JAK10.65204847
89TNK20.61752634
90MAPK100.61404814
91CSNK1G30.59007927
92* CSNK1D0.58883961
93FYN0.58558615
94NUAK10.58313865
95BCR0.57809566
96RPS6KA30.57428451
97ERBB20.56685995
98JAK20.56101981
99MAP3K130.55742951
100TRIB30.55455571
101CSNK1G10.54591690
102RPS6KB10.54332498
103MAPK80.53676192
104BMX0.53259719
105CSK0.52584094
106BTK0.52427758
107ACVR1B0.52006985
108PDK10.50746942
109HCK0.50577205
110FES0.49819039
111RPS6KA40.49164995
112TRIM280.48745690
113CDK150.48485993
114MTOR0.48218645
115CDK180.48119657
116MAPK70.46965476
117MAP3K60.46404175
118CDK30.45973005
119CDK140.45491496
120IRAK20.45313592
121GSK3B0.45261683
122PRKCZ0.44765072
123DDR20.44703810
124CAMK10.44039171
125PTK2B0.43781100
126CAMK2A0.42913054
127ROCK20.41496293
128ITK0.40648705
129MAP3K140.40375471
130FER0.39715709
131RPS6KA20.39399131
132MAPK120.39277581
133BLK0.38547481
134RAF10.38203790
135CDK11A0.38201560
136SYK0.37844626
137PRKAA10.36693953
138MARK30.35975574
139NEK60.34438675

Predicted pathways (KEGG)

RankGene SetZ-score
1Long-term potentiation_Homo sapiens_hsa047202.16731847
2Olfactory transduction_Homo sapiens_hsa047401.98655425
3Nicotine addiction_Homo sapiens_hsa050331.95022676
4Dorso-ventral axis formation_Homo sapiens_hsa043201.83538636
5Circadian entrainment_Homo sapiens_hsa047131.83535377
6Glutamatergic synapse_Homo sapiens_hsa047241.72057666
7Dopaminergic synapse_Homo sapiens_hsa047281.71689335
8Morphine addiction_Homo sapiens_hsa050321.69547000
9Amphetamine addiction_Homo sapiens_hsa050311.67177848
10Synaptic vesicle cycle_Homo sapiens_hsa047211.62264174
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.61753177
12GABAergic synapse_Homo sapiens_hsa047271.59083395
13Axon guidance_Homo sapiens_hsa043601.51249789
14Glioma_Homo sapiens_hsa052141.50750031
15Cholinergic synapse_Homo sapiens_hsa047251.48754454
16Renin secretion_Homo sapiens_hsa049241.47919825
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.45361241
18Phosphatidylinositol signaling system_Homo sapiens_hsa040701.42738682
19Oxytocin signaling pathway_Homo sapiens_hsa049211.42631447
20ErbB signaling pathway_Homo sapiens_hsa040121.41414864
21Salivary secretion_Homo sapiens_hsa049701.41214090
22Gastric acid secretion_Homo sapiens_hsa049711.39134410
23Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.37375001
24Endometrial cancer_Homo sapiens_hsa052131.37131169
25GnRH signaling pathway_Homo sapiens_hsa049121.33179938
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.33121619
27Estrogen signaling pathway_Homo sapiens_hsa049151.32880152
28Type II diabetes mellitus_Homo sapiens_hsa049301.30748814
29Long-term depression_Homo sapiens_hsa047301.29273114
30Colorectal cancer_Homo sapiens_hsa052101.25898252
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.25236099
32mTOR signaling pathway_Homo sapiens_hsa041501.20493955
33Cocaine addiction_Homo sapiens_hsa050301.19642072
34Gap junction_Homo sapiens_hsa045401.19263158
35Neurotrophin signaling pathway_Homo sapiens_hsa047221.15209860
36Insulin secretion_Homo sapiens_hsa049111.14831216
37Melanogenesis_Homo sapiens_hsa049161.11626996
38T cell receptor signaling pathway_Homo sapiens_hsa046601.10476804
39Acute myeloid leukemia_Homo sapiens_hsa052211.10249386
40Renal cell carcinoma_Homo sapiens_hsa052111.09337478
41Notch signaling pathway_Homo sapiens_hsa043301.08424150
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.07603094
43Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.06895200
44Non-small cell lung cancer_Homo sapiens_hsa052231.04542982
45cAMP signaling pathway_Homo sapiens_hsa040241.04416835
46Serotonergic synapse_Homo sapiens_hsa047261.03049846
47Thyroid hormone signaling pathway_Homo sapiens_hsa049191.02950818
48cGMP-PKG signaling pathway_Homo sapiens_hsa040221.02866014
49Circadian rhythm_Homo sapiens_hsa047101.00698055
50Chronic myeloid leukemia_Homo sapiens_hsa052201.00286998
51MAPK signaling pathway_Homo sapiens_hsa040100.99968053
52VEGF signaling pathway_Homo sapiens_hsa043700.96004206
53Calcium signaling pathway_Homo sapiens_hsa040200.95148955
54Taste transduction_Homo sapiens_hsa047420.94487059
55Wnt signaling pathway_Homo sapiens_hsa043100.94096485
56Oocyte meiosis_Homo sapiens_hsa041140.92934811
57Choline metabolism in cancer_Homo sapiens_hsa052310.92743553
58Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.92580293
59Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.92392543
60Phospholipase D signaling pathway_Homo sapiens_hsa040720.90073038
61Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.89733954
62Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.89545057
63Adherens junction_Homo sapiens_hsa045200.89407199
64Inositol phosphate metabolism_Homo sapiens_hsa005620.88806581
65Lysine degradation_Homo sapiens_hsa003100.88499317
66Hedgehog signaling pathway_Homo sapiens_hsa043400.87986764
67Rap1 signaling pathway_Homo sapiens_hsa040150.87669839
68Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.86205040
69Hippo signaling pathway_Homo sapiens_hsa043900.83578525
70Pancreatic cancer_Homo sapiens_hsa052120.83197179
71Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.79511213
72B cell receptor signaling pathway_Homo sapiens_hsa046620.78927671
73Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.78499283
74Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.78390931
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.78280956
76FoxO signaling pathway_Homo sapiens_hsa040680.77881672
77Chemokine signaling pathway_Homo sapiens_hsa040620.77646979
78Ras signaling pathway_Homo sapiens_hsa040140.76687508
79Sphingolipid signaling pathway_Homo sapiens_hsa040710.76351787
80Proteoglycans in cancer_Homo sapiens_hsa052050.76223639
81Longevity regulating pathway - mammal_Homo sapiens_hsa042110.75998165
82MicroRNAs in cancer_Homo sapiens_hsa052060.75247457
83Vascular smooth muscle contraction_Homo sapiens_hsa042700.74877267
84Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.73915339
85Dilated cardiomyopathy_Homo sapiens_hsa054140.73461603
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.72959554
87Jak-STAT signaling pathway_Homo sapiens_hsa046300.72701166
88Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.71835909
89Hepatitis B_Homo sapiens_hsa051610.71328402
90Prolactin signaling pathway_Homo sapiens_hsa049170.70084930
91Focal adhesion_Homo sapiens_hsa045100.69947000
92Phototransduction_Homo sapiens_hsa047440.69677228
93Measles_Homo sapiens_hsa051620.69586490
94Tight junction_Homo sapiens_hsa045300.67987253
95Insulin signaling pathway_Homo sapiens_hsa049100.66975644
96Endocytosis_Homo sapiens_hsa041440.66877374
97Basal cell carcinoma_Homo sapiens_hsa052170.66315259
98Prostate cancer_Homo sapiens_hsa052150.66164043
99AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.66142408
100Platelet activation_Homo sapiens_hsa046110.65788646
101AMPK signaling pathway_Homo sapiens_hsa041520.65317041
102Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.64954979
103Regulation of actin cytoskeleton_Homo sapiens_hsa048100.64540841
104Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64109119
105Viral myocarditis_Homo sapiens_hsa054160.63937835
106Leukocyte transendothelial migration_Homo sapiens_hsa046700.63865673
107Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.62721621
108Central carbon metabolism in cancer_Homo sapiens_hsa052300.62146991
109Alcoholism_Homo sapiens_hsa050340.61117506
110Osteoclast differentiation_Homo sapiens_hsa043800.59030986
111Glucagon signaling pathway_Homo sapiens_hsa049220.58553117
112Thyroid cancer_Homo sapiens_hsa052160.58414382
113Pathways in cancer_Homo sapiens_hsa052000.57673508
114Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57339380
115mRNA surveillance pathway_Homo sapiens_hsa030150.56768252
116NOD-like receptor signaling pathway_Homo sapiens_hsa046210.54257360
117Hepatitis C_Homo sapiens_hsa051600.51340453

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