MGME1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)4.99994783
2DNA replication initiation (GO:0006270)4.90110201
3DNA strand elongation (GO:0022616)4.77752072
4telomere maintenance via semi-conservative replication (GO:0032201)4.74617036
5mitotic metaphase plate congression (GO:0007080)4.72682930
6sister chromatid segregation (GO:0000819)4.71897715
7nucleobase biosynthetic process (GO:0046112)4.63784614
8establishment of integrated proviral latency (GO:0075713)4.58527204
9DNA deamination (GO:0045006)4.57816568
10purine nucleobase biosynthetic process (GO:0009113)4.54839622
11nuclear pore complex assembly (GO:0051292)4.53012846
12DNA replication checkpoint (GO:0000076)4.40836851
13DNA unwinding involved in DNA replication (GO:0006268)4.36296885
14metaphase plate congression (GO:0051310)4.35434504
15ribosomal small subunit assembly (GO:0000028)4.34444829
16maturation of SSU-rRNA (GO:0030490)4.27578126
17telomere maintenance via recombination (GO:0000722)4.24386765
18telomere maintenance via telomere lengthening (GO:0010833)4.15232549
19CENP-A containing nucleosome assembly (GO:0034080)4.12420711
20DNA ligation (GO:0006266)4.10540121
21chromatin remodeling at centromere (GO:0031055)4.08891678
22formation of translation preinitiation complex (GO:0001731)4.07481972
23mitotic recombination (GO:0006312)3.98595288
24regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.98491398
25ribosomal large subunit biogenesis (GO:0042273)3.95923887
26IMP biosynthetic process (GO:0006188)3.94469577
27DNA topological change (GO:0006265)3.92565022
28heterochromatin organization (GO:0070828)3.88074961
29spindle checkpoint (GO:0031577)3.87578605
30protein localization to kinetochore (GO:0034501)3.81159683
31ribosome biogenesis (GO:0042254)3.81054048
32pseudouridine synthesis (GO:0001522)3.80098898
33ribonucleoprotein complex biogenesis (GO:0022613)3.78469574
34negative regulation of mitotic sister chromatid separation (GO:2000816)3.78435582
35negative regulation of sister chromatid segregation (GO:0033046)3.78435582
36negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.78435582
37negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.78435582
38mitotic sister chromatid cohesion (GO:0007064)3.76944434
39regulation of chromosome segregation (GO:0051983)3.74442580
40mitotic spindle checkpoint (GO:0071174)3.73947620
41kinetochore organization (GO:0051383)3.73379437
42regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.70036607
43ribosomal small subunit biogenesis (GO:0042274)3.69124985
44DNA replication-independent nucleosome assembly (GO:0006336)3.64620132
45DNA replication-independent nucleosome organization (GO:0034724)3.64620132
46meiotic chromosome segregation (GO:0045132)3.64066270
47proteasome assembly (GO:0043248)3.63872610
48establishment of chromosome localization (GO:0051303)3.61326228
49nucleotide-excision repair, DNA gap filling (GO:0006297)3.60430288
50IMP metabolic process (GO:0046040)3.60184904
51kinetochore assembly (GO:0051382)3.59839775
52ribosome assembly (GO:0042255)3.59462665
53mitotic spindle assembly checkpoint (GO:0007094)3.56911589
54spindle assembly checkpoint (GO:0071173)3.55445999
55regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.55088523
56regulation of mitotic metaphase/anaphase transition (GO:0030071)3.55088523
57mitotic nuclear envelope disassembly (GO:0007077)3.51179410
58rRNA processing (GO:0006364)3.49479901
59DNA replication-dependent nucleosome organization (GO:0034723)3.48572816
60DNA replication-dependent nucleosome assembly (GO:0006335)3.48572816
61viral transcription (GO:0019083)3.47658122
62translational termination (GO:0006415)3.46282364
63regulation of mitotic sister chromatid separation (GO:0010965)3.45498967
64regulation of mitotic sister chromatid segregation (GO:0033047)3.45498967
65regulation of sister chromatid segregation (GO:0033045)3.45498967
66attachment of spindle microtubules to kinetochore (GO:0008608)3.44484983
67regulation of mitotic spindle organization (GO:0060236)3.43223751
68non-recombinational repair (GO:0000726)3.42426521
69double-strand break repair via nonhomologous end joining (GO:0006303)3.42426521
70establishment of viral latency (GO:0019043)3.41943816
71spliceosomal snRNP assembly (GO:0000387)3.41196424
72folic acid-containing compound biosynthetic process (GO:0009396)3.40578399
73chromosome segregation (GO:0007059)3.39899674
74chromosome condensation (GO:0030261)3.37333517
75rRNA metabolic process (GO:0016072)3.36105093
76histone exchange (GO:0043486)3.34941564
77chromatin assembly or disassembly (GO:0006333)3.34249566
78protein localization to chromosome, centromeric region (GO:0071459)3.33219812
79translational elongation (GO:0006414)3.30340221
80regulation of centriole replication (GO:0046599)3.30088694
81rRNA modification (GO:0000154)3.30043617
82somatic hypermutation of immunoglobulin genes (GO:0016446)3.30016009
83somatic diversification of immune receptors via somatic mutation (GO:0002566)3.30016009
84regulation of spindle organization (GO:0090224)3.27958587
85protein localization to chromosome (GO:0034502)3.27574564
86positive regulation of chromosome segregation (GO:0051984)3.26217133
87pore complex assembly (GO:0046931)3.25791016
88mitotic G2/M transition checkpoint (GO:0044818)3.23668760
89regulation of sister chromatid cohesion (GO:0007063)3.23497937
90ATP-dependent chromatin remodeling (GO:0043044)3.22816025
91membrane disassembly (GO:0030397)3.21311064
92nuclear envelope disassembly (GO:0051081)3.21311064
93translational initiation (GO:0006413)3.21304515
94transcription-coupled nucleotide-excision repair (GO:0006283)3.21182969
95regulation of DNA endoreduplication (GO:0032875)3.19330035
96regulation of double-strand break repair via homologous recombination (GO:0010569)3.17679296
97viral mRNA export from host cell nucleus (GO:0046784)3.16475988
98deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.15300491
99synapsis (GO:0007129)3.15089225
100anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.11840831
101regulation of nuclear cell cycle DNA replication (GO:0033262)3.10585420
102telomere organization (GO:0032200)3.09890818
103negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.09078546
104telomere maintenance (GO:0000723)3.08906963
105cellular component biogenesis (GO:0044085)3.08716823
106mismatch repair (GO:0006298)3.08008232
107telomere maintenance via telomerase (GO:0007004)3.07465304
108regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.06074834
109nuclear pore organization (GO:0006999)3.06034122
110folic acid metabolic process (GO:0046655)3.05988797
111mitotic sister chromatid segregation (GO:0000070)3.05820650
112negative regulation of ligase activity (GO:0051352)3.05403435
113negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.05403435
114DNA packaging (GO:0006323)3.04691017
115mitotic chromosome condensation (GO:0007076)3.03934930
116exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.03751206
117DNA synthesis involved in DNA repair (GO:0000731)3.03415539
118negative regulation of mitosis (GO:0045839)3.03063009
119cell cycle G1/S phase transition (GO:0044843)3.01483876
120G1/S transition of mitotic cell cycle (GO:0000082)3.01483876
121positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.00031148
122base-excision repair (GO:0006284)2.98353067
123regulation of centrosome cycle (GO:0046605)2.97353609
124spliceosomal complex assembly (GO:0000245)2.96154556
125SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.95192216
126nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.92378213
127termination of RNA polymerase III transcription (GO:0006386)2.90741301
128transcription elongation from RNA polymerase III promoter (GO:0006385)2.90741301
129DNA duplex unwinding (GO:0032508)2.89563902
130DNA geometric change (GO:0032392)2.88095007
131nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.87915859
132transcription from mitochondrial promoter (GO:0006390)2.87845290
133RNA-dependent DNA replication (GO:0006278)2.87590721
134cotranslational protein targeting to membrane (GO:0006613)2.87402420
135mitochondrial RNA metabolic process (GO:0000959)2.87290687
136maturation of 5.8S rRNA (GO:0000460)2.86698957
137regulation of helicase activity (GO:0051095)2.86211958
138protein targeting to ER (GO:0045047)2.85430626
139translation (GO:0006412)2.85123364
140negative regulation of telomerase activity (GO:0051974)2.84359126
141* DNA-dependent DNA replication (GO:0006261)2.83304269
142termination of RNA polymerase I transcription (GO:0006363)2.81102497
143negative regulation of chromosome segregation (GO:0051985)2.79885615
144* DNA replication (GO:0006260)2.78604771
145negative regulation of mitotic sister chromatid segregation (GO:0033048)2.78535824

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.31093643
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.36284121
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.54016020
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.48805805
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.47911485
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.45999674
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.04711208
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.99177591
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.97941485
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.97899898
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.91243707
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.88540291
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.87284378
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.79772711
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.61334881
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.45046363
17E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.39442455
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.38104273
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.33119826
20VDR_23849224_ChIP-Seq_CD4+_Human2.23943946
21XRN2_22483619_ChIP-Seq_HELA_Human2.22994214
22NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.14654434
23E2F1_18555785_ChIP-Seq_MESCs_Mouse2.14253352
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.11754780
25DCP1A_22483619_ChIP-Seq_HELA_Human2.07139462
26SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.05313364
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.03971301
28FOXP3_21729870_ChIP-Seq_TREG_Human2.01604893
29AR_21909140_ChIP-Seq_LNCAP_Human1.97524477
30MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.95007780
31E2F1_21310950_ChIP-Seq_MCF-7_Human1.89462682
32HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.88184522
33GABP_19822575_ChIP-Seq_HepG2_Human1.86111733
34POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.85748974
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85243482
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.80760010
37NANOG_18555785_ChIP-Seq_MESCs_Mouse1.79113363
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.77115564
39THAP11_20581084_ChIP-Seq_MESCs_Mouse1.76042860
40TTF2_22483619_ChIP-Seq_HELA_Human1.75089557
41YY1_21170310_ChIP-Seq_MESCs_Mouse1.70923970
42SRF_21415370_ChIP-Seq_HL-1_Mouse1.65612575
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.65442128
44FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.64582401
45CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.57597859
46YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.55902678
47ELK1_19687146_ChIP-ChIP_HELA_Human1.55166477
48MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.54225260
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.53491325
50KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.51568296
51ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.50855802
52ZFX_18555785_ChIP-Seq_MESCs_Mouse1.48388024
53STAT3_1855785_ChIP-Seq_MESCs_Mouse1.39272439
54ERG_20887958_ChIP-Seq_HPC-7_Mouse1.37709447
55PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.36901190
56CIITA_25753668_ChIP-Seq_RAJI_Human1.36387077
57POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.34783421
58SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.34608376
59KDM5A_27292631_Chip-Seq_BREAST_Human1.33466916
60FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.31957106
61SALL1_21062744_ChIP-ChIP_HESCs_Human1.30155402
62EGR1_19374776_ChIP-ChIP_THP-1_Human1.29503992
63SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.27883489
64POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.27745453
65PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.20517334
66SOX2_18555785_ChIP-Seq_MESCs_Mouse1.18136173
67CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.17158011
68NOTCH1_21737748_ChIP-Seq_TLL_Human1.15485269
69MYC_22102868_ChIP-Seq_BL_Human1.14863303
70E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.12461435
71TFEB_21752829_ChIP-Seq_HELA_Human1.11737935
72RBPJ_22232070_ChIP-Seq_NCS_Mouse1.10924912
73HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.10537272
74KLF4_18555785_ChIP-Seq_MESCs_Mouse1.10141552
75ESR1_15608294_ChIP-ChIP_MCF-7_Human1.09908096
76NANOG_16153702_ChIP-ChIP_HESCs_Human1.09390969
77SOX17_20123909_ChIP-Seq_XEN_Mouse1.08301671
78PADI4_21655091_ChIP-ChIP_MCF-7_Human1.07822710
79ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.05739259
80BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.05408921
81ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.02297590
82HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.00963698
83SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.98584322
84KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.98244546
85MYC_18940864_ChIP-ChIP_HL60_Human0.97916016
86KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.97638627
87KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.97638627
88KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.97638627
89GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94925159
90CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92049151
91DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.91725449
92SPI1_23547873_ChIP-Seq_NB4_Human0.91248387
93SOX2_16153702_ChIP-ChIP_HESCs_Human0.89466033
94CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.86387223
95SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.83748352
96CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.83198343
97KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.82576751
98NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.82322624
99TCF3_18692474_ChIP-Seq_MEFs_Mouse0.82078796
100SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.81734382
101TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.81525941
102NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.80935611
103CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.80753961
104CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.80731608
105NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.79526409
106CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.78343607
107HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.77935925
108ELK1_22589737_ChIP-Seq_MCF10A_Human0.77833199
109SOX2_18692474_ChIP-Seq_MEFs_Mouse0.77072365
110OCT4_18692474_ChIP-Seq_MEFs_Mouse0.74732692
111NANOG_21062744_ChIP-ChIP_HESCs_Human0.73867945
112SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.73581500
113CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.73395779
114CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.72320573

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.54717011
2MP0010094_abnormal_chromosome_stability4.83335409
3MP0003111_abnormal_nucleus_morphology4.52525455
4MP0004957_abnormal_blastocyst_morpholog4.45576162
5MP0003077_abnormal_cell_cycle3.95580120
6MP0008057_abnormal_DNA_replication3.93103078
7MP0008058_abnormal_DNA_repair3.73584826
8MP0003806_abnormal_nucleotide_metabolis2.84554814
9MP0008007_abnormal_cellular_replicative2.83721336
10MP0008932_abnormal_embryonic_tissue2.52254034
11MP0002396_abnormal_hematopoietic_system2.51158023
12MP0003123_paternal_imprinting2.50712912
13MP0008877_abnormal_DNA_methylation2.35456313
14MP0001730_embryonic_growth_arrest2.20152236
15MP0000350_abnormal_cell_proliferation1.99338468
16MP0003718_maternal_effect1.97910104
17MP0003786_premature_aging1.92564471
18MP0010030_abnormal_orbit_morphology1.85535253
19MP0000490_abnormal_crypts_of1.82963720
20MP0003186_abnormal_redox_activity1.73124477
21MP0001672_abnormal_embryogenesis/_devel1.70878707
22MP0005380_embryogenesis_phenotype1.70878707
23MP0010352_gastrointestinal_tract_polyps1.66740990
24MP0001697_abnormal_embryo_size1.62103120
25MP0010307_abnormal_tumor_latency1.54021957
26MP0000313_abnormal_cell_death1.52371444
27MP0003984_embryonic_growth_retardation1.51480413
28MP0002080_prenatal_lethality1.51402888
29MP0003567_abnormal_fetal_cardiomyocyte1.49720499
30MP0002088_abnormal_embryonic_growth/wei1.48262565
31MP0004808_abnormal_hematopoietic_stem1.45988278
32MP0002938_white_spotting1.45517667
33MP0006036_abnormal_mitochondrial_physio1.45243166
34MP0002019_abnormal_tumor_incidence1.38909208
35MP0005408_hypopigmentation1.34048634
36MP0006292_abnormal_olfactory_placode1.31490779
37MP0009333_abnormal_splenocyte_physiolog1.29290786
38MP0002085_abnormal_embryonic_tissue1.29138802
39MP0002210_abnormal_sex_determination1.28539210
40MP0002086_abnormal_extraembryonic_tissu1.27872298
41MP0001545_abnormal_hematopoietic_system1.27526777
42MP0005397_hematopoietic_system_phenotyp1.27526777
43MP0003221_abnormal_cardiomyocyte_apopto1.23407650
44MP0005075_abnormal_melanosome_morpholog1.20285601
45MP0004147_increased_porphyrin_level1.20276530
46MP0003136_yellow_coat_color1.19863599
47MP0003937_abnormal_limbs/digits/tail_de1.16212787
48MP0002697_abnormal_eye_size1.15808498
49MP0002084_abnormal_developmental_patter1.13634647
50MP0006035_abnormal_mitochondrial_morpho1.13159866
51MP0001145_abnormal_male_reproductive1.11263651
52MP0004133_heterotaxia1.08896669
53MP0000372_irregular_coat_pigmentation1.08415381
54MP0001293_anophthalmia1.08210958
55MP0001286_abnormal_eye_development1.06136206
56MP0004197_abnormal_fetal_growth/weight/1.04943423
57MP0000689_abnormal_spleen_morphology1.04835896
58MP0003890_abnormal_embryonic-extraembry1.03085231
59MP0002722_abnormal_immune_system1.01855200
60MP0009379_abnormal_foot_pigmentation1.00308179
61MP0002398_abnormal_bone_marrow0.99072796
62MP0002132_abnormal_respiratory_system0.98792530
63MP0003763_abnormal_thymus_physiology0.98184140
64MP0005501_abnormal_skin_physiology0.97374043
65MP0001929_abnormal_gametogenesis0.97114067
66MP0000703_abnormal_thymus_morphology0.95956168
67MP0001853_heart_inflammation0.95696167
68MP0000653_abnormal_sex_gland0.94768751
69MP0000358_abnormal_cell_content/0.93800625
70MP0003315_abnormal_perineum_morphology0.93273109
71MP0008260_abnormal_autophagy0.92160047
72MP0001119_abnormal_female_reproductive0.90283826
73MP0002796_impaired_skin_barrier0.90185187
74MP0002092_abnormal_eye_morphology0.89624021
75MP0009697_abnormal_copulation0.88135884
76MP0009672_abnormal_birth_weight0.88068320
77MP0004264_abnormal_extraembryonic_tissu0.86433356
78MP0002877_abnormal_melanocyte_morpholog0.85515495
79MP0002429_abnormal_blood_cell0.85341307
80MP0003950_abnormal_plasma_membrane0.85283976
81MP0002233_abnormal_nose_morphology0.84957808
82MP0009703_decreased_birth_body0.84273456
83MP0001764_abnormal_homeostasis0.82286883
84MP0000579_abnormal_nail_morphology0.81911076
85MP0005076_abnormal_cell_differentiation0.81527083
86MP0009053_abnormal_anal_canal0.81403521
87MP0003121_genomic_imprinting0.80821159
88MP0001346_abnormal_lacrimal_gland0.80605875
89MP0005266_abnormal_metabolism0.80159529
90MP0008789_abnormal_olfactory_epithelium0.80018410
91MP0000537_abnormal_urethra_morphology0.77406492
92MP0001661_extended_life_span0.75180857
93MP0003705_abnormal_hypodermis_morpholog0.74911107
94MP0002160_abnormal_reproductive_system0.73518863
95MP0005257_abnormal_intraocular_pressure0.73371966
96MP0001986_abnormal_taste_sensitivity0.72434457
97MP0001915_intracranial_hemorrhage0.70550261
98MP0000477_abnormal_intestine_morphology0.70107585
99MP0003943_abnormal_hepatobiliary_system0.69997174
100MP0000762_abnormal_tongue_morphology0.69789894
101MP0000428_abnormal_craniofacial_morphol0.69569133
102MP0000647_abnormal_sebaceous_gland0.69556404
103MP0002095_abnormal_skin_pigmentation0.68956343
104MP0005384_cellular_phenotype0.68951721
105MP0004084_abnormal_cardiac_muscle0.68442457
106MP0000627_abnormal_mammary_gland0.67189492
107MP0000716_abnormal_immune_system0.66986046
108MP0001881_abnormal_mammary_gland0.66112976
109MP0009840_abnormal_foam_cell0.64012473
110MP0000566_synostosis0.63898483
111MP0000858_altered_metastatic_potential0.63414223
112MP0003119_abnormal_digestive_system0.63217674
113MP0001186_pigmentation_phenotype0.61755552
114MP0000598_abnormal_liver_morphology0.60354638
115MP0003566_abnormal_cell_adhesion0.60332922
116MP0005621_abnormal_cell_physiology0.58430984
117MP0005389_reproductive_system_phenotype0.58355850
118MP0000678_abnormal_parathyroid_gland0.58234712
119MP0002111_abnormal_tail_morphology0.58125985
120MP0003755_abnormal_palate_morphology0.57237408
121MP0001216_abnormal_epidermal_layer0.57032049
122MP0003698_abnormal_male_reproductive0.56494889
123MP0000750_abnormal_muscle_regeneration0.55058174
124MP0006054_spinal_hemorrhage0.54926027
125MP0005330_cardiomyopathy0.52731138
126MP0005319_abnormal_enzyme/_coenzyme0.52263383
127MP0005670_abnormal_white_adipose0.51624746
128MP0001835_abnormal_antigen_presentation0.49795021
129MP0001800_abnormal_humoral_immune0.49745431
130MP0001873_stomach_inflammation0.49481883
131MP0009278_abnormal_bone_marrow0.49244554
132MP0005174_abnormal_tail_pigmentation0.48713006
133MP0003699_abnormal_female_reproductive0.48631793
134MP0002420_abnormal_adaptive_immunity0.48053639
135MP0002075_abnormal_coat/hair_pigmentati0.48027671
136MP0003941_abnormal_skin_development0.47878039
137MP0001819_abnormal_immune_cell0.46751897
138MP0003656_abnormal_erythrocyte_physiolo0.46282082

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.80983640
2Abnormality of cells of the erythroid lineage (HP:0012130)4.75220857
3Abnormal number of erythroid precursors (HP:0012131)4.73165215
4Reticulocytopenia (HP:0001896)4.17449856
5Oral leukoplakia (HP:0002745)4.15032811
6Breast hypoplasia (HP:0003187)3.76969432
7Nephroblastoma (Wilms tumor) (HP:0002667)3.74138755
8Degeneration of anterior horn cells (HP:0002398)3.66672958
9Abnormality of the anterior horn cell (HP:0006802)3.66672958
10Chromsome breakage (HP:0040012)3.62343578
11Colon cancer (HP:0003003)3.62111658
12Embryonal renal neoplasm (HP:0011794)3.49855988
13Chromosomal breakage induced by crosslinking agents (HP:0003221)3.49349691
14Rough bone trabeculation (HP:0100670)3.43823021
15Agnosia (HP:0010524)3.06100279
16Selective tooth agenesis (HP:0001592)3.00008688
17Increased nuchal translucency (HP:0010880)2.94251321
18Microretrognathia (HP:0000308)2.92349143
19Overlapping toe (HP:0001845)2.91915041
20Ependymoma (HP:0002888)2.90192268
21Abnormality of the preputium (HP:0100587)2.88910426
22Medulloblastoma (HP:0002885)2.87147326
23Carpal bone hypoplasia (HP:0001498)2.86071140
24Macrocytic anemia (HP:0001972)2.85529398
25Abnormality of chromosome stability (HP:0003220)2.77744145
26Microvesicular hepatic steatosis (HP:0001414)2.73614643
27Aplastic anemia (HP:0001915)2.71104832
28Increased serum lactate (HP:0002151)2.70177721
29Pallor (HP:0000980)2.69447672
30Meckel diverticulum (HP:0002245)2.66942765
31Abnormal trabecular bone morphology (HP:0100671)2.65757676
32Impulsivity (HP:0100710)2.65388643
33Rib fusion (HP:0000902)2.64868323
34Decreased activity of mitochondrial respiratory chain (HP:0008972)2.64764962
35Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.64764962
36Absent thumb (HP:0009777)2.64357787
37Cerebral hypomyelination (HP:0006808)2.63669179
38Supernumerary spleens (HP:0009799)2.63385556
39Patellar aplasia (HP:0006443)2.63011629
40Cellular immunodeficiency (HP:0005374)2.58807769
41Rhabdomyosarcoma (HP:0002859)2.56607412
42Abnormality of the labia minora (HP:0012880)2.55843876
43Abnormality of the ileum (HP:0001549)2.55180993
44Asplenia (HP:0001746)2.52838519
45Progressive muscle weakness (HP:0003323)2.49815504
46Myelodysplasia (HP:0002863)2.47706263
47Type I transferrin isoform profile (HP:0003642)2.47007443
48Bone marrow hypocellularity (HP:0005528)2.46679893
49Sparse eyelashes (HP:0000653)2.45745863
50Abnormality of pyrimidine metabolism (HP:0004353)2.45239944
51Premature graying of hair (HP:0002216)2.44791584
52Neoplasm of the pancreas (HP:0002894)2.43345407
53Aplasia/Hypoplasia of the patella (HP:0006498)2.43029804
54Abnormality of the carotid arteries (HP:0005344)2.42452902
55Aplasia/Hypoplasia of the spleen (HP:0010451)2.40454304
56Hepatic necrosis (HP:0002605)2.34610146
57Volvulus (HP:0002580)2.34221804
58Spinal muscular atrophy (HP:0007269)2.32177254
59Hepatocellular necrosis (HP:0001404)2.29368375
60Duplication of thumb phalanx (HP:0009942)2.28406514
61Duplicated collecting system (HP:0000081)2.27644908
62Aplasia/Hypoplasia of the uvula (HP:0010293)2.27437448
63Absent radius (HP:0003974)2.25386202
64Multiple enchondromatosis (HP:0005701)2.24160393
65Pancytopenia (HP:0001876)2.22218130
66Thrombocytosis (HP:0001894)2.20761274
67Cafe-au-lait spot (HP:0000957)2.18045967
68IgM deficiency (HP:0002850)2.18027608
69Hypoplasia of the capital femoral epiphysis (HP:0003090)2.17050678
70Clubbing of toes (HP:0100760)2.14762983
71Abnormality of the renal collecting system (HP:0004742)2.14499611
72Duodenal stenosis (HP:0100867)2.13430357
73Small intestinal stenosis (HP:0012848)2.13430357
74Abnormality of methionine metabolism (HP:0010901)2.12828724
75Irregular epiphyses (HP:0010582)2.12736899
76Horseshoe kidney (HP:0000085)2.12582658
77Megaloblastic anemia (HP:0001889)2.11411140
78Abnormal lung lobation (HP:0002101)2.11402052
79Hypoplastic pelvis (HP:0008839)2.10865474
80Sloping forehead (HP:0000340)2.10717905
81Proximal placement of thumb (HP:0009623)2.10668429
82Embryonal neoplasm (HP:0002898)2.08376899
83Shawl scrotum (HP:0000049)2.06352880
8411 pairs of ribs (HP:0000878)2.06169666
85Choanal atresia (HP:0000453)2.06069801
86Aplasia involving forearm bones (HP:0009822)2.04907259
87Absent forearm bone (HP:0003953)2.04907259
88* Progressive external ophthalmoplegia (HP:0000590)2.04291801
89Abnormal spermatogenesis (HP:0008669)2.03505202
90Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.02140436
91Microglossia (HP:0000171)2.01177717
92Abnormality of cochlea (HP:0000375)2.00549878
93Deviation of the thumb (HP:0009603)1.98227757
94Atrophy/Degeneration involving motor neurons (HP:0007373)1.98015376
95Increased CSF lactate (HP:0002490)1.96934844
96Lymphoma (HP:0002665)1.96741354
97Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.96693355
98Increased hepatocellular lipid droplets (HP:0006565)1.96624717
99Abnormality of serum amino acid levels (HP:0003112)1.95660656
100Tracheoesophageal fistula (HP:0002575)1.95203876
101Trismus (HP:0000211)1.95182824
102Ureteral duplication (HP:0000073)1.95136011
103Small epiphyses (HP:0010585)1.94519738
104Neoplasm of the colon (HP:0100273)1.94211482
105Amaurosis fugax (HP:0100576)1.93300187
106Reduced antithrombin III activity (HP:0001976)1.92825832
107Short thumb (HP:0009778)1.91488934
108Premature ovarian failure (HP:0008209)1.91343423
109Triphalangeal thumb (HP:0001199)1.88028393
110Abnormality of aspartate family amino acid metabolism (HP:0010899)1.87554939
111Facial cleft (HP:0002006)1.87472326
112Abnormality of the duodenum (HP:0002246)1.87450143
1133-Methylglutaconic aciduria (HP:0003535)1.86513772
114Pancreatic islet-cell hyperplasia (HP:0004510)1.85417814
115Self-mutilation (HP:0000742)1.85203142
116Squamous cell carcinoma (HP:0002860)1.85144378
117Basal cell carcinoma (HP:0002671)1.84227667
118Cortical dysplasia (HP:0002539)1.84213428
119Spastic diplegia (HP:0001264)1.83837267
120Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.83778786
121Ectopic kidney (HP:0000086)1.83455582
122Aplasia/Hypoplasia of the sacrum (HP:0008517)1.81996264
123Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.81176157
124Absent epiphyses (HP:0010577)1.81176157
125Short middle phalanx of the 5th finger (HP:0004220)1.80317520
126Abnormality of lateral ventricle (HP:0030047)1.78075049
127Abnormal number of incisors (HP:0011064)1.77764317
128Muscle fiber atrophy (HP:0100295)1.77589557
129Abnormality of the fetal cardiovascular system (HP:0010948)1.76149524
130Abnormal umbilical cord blood vessels (HP:0011403)1.76149524
131Single umbilical artery (HP:0001195)1.76149524
132Type 2 muscle fiber atrophy (HP:0003554)1.74831389
133Acute encephalopathy (HP:0006846)1.74463429
134Hyperglycinemia (HP:0002154)1.74036717
135Abnormality of glycolysis (HP:0004366)1.73994702
136Increased serum pyruvate (HP:0003542)1.73994702
137Slender long bone (HP:0003100)1.73697981
138Abnormal glycosylation (HP:0012345)1.73318956
139Capillary hemangiomas (HP:0005306)1.72580447
140Abnormality of glycine metabolism (HP:0010895)1.72499747
141Abnormality of serine family amino acid metabolism (HP:0010894)1.72499747
142Cleft eyelid (HP:0000625)1.71551833
143Malignant gastrointestinal tract tumors (HP:0006749)1.70860587
144Gastrointestinal carcinoma (HP:0002672)1.70860587
145Glioma (HP:0009733)1.70753930
146Abnormality of the umbilical cord (HP:0010881)1.70723851

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE14.42357249
2BUB14.41550176
3CDC73.68567003
4EIF2AK13.67965906
5VRK23.08087550
6VRK12.82115329
7TSSK62.72360666
8NEK22.72358428
9NME22.42956122
10TTK2.38513589
11NEK12.35159363
12STK162.32146095
13MST42.19836220
14ACVR1B2.15165339
15EIF2AK32.11017144
16PLK42.03184631
17BRSK22.03168953
18TAF12.01094961
19PLK11.99149877
20SRPK11.95374465
21RPS6KA41.73826911
22MKNK11.72616152
23CDK71.70312454
24BCKDK1.66153895
25AURKB1.58304628
26ATR1.56561573
27PLK31.56188265
28RPS6KB21.52885825
29TIE11.49193303
30STK41.44514163
31EPHA21.40132449
32MAP2K31.38990917
33TLK11.38123538
34SMG11.32850286
35DYRK31.29982153
36MKNK21.27554734
37PASK1.26954413
38MAP3K81.24163511
39MAP4K11.22102777
40CHEK21.19817072
41CDK41.19248509
42ZAK1.15649155
43EEF2K1.14993209
44MAP3K101.14537467
45STK101.14058564
46BRSK11.10366468
47AURKA1.08025258
48CCNB11.06342067
49TRIM281.06008903
50CDK121.04841296
51TGFBR11.03062925
52NUAK11.01809317
53CDK81.01249455
54PAK41.00958538
55PBK0.99299499
56TESK20.98914114
57STK30.98712003
58CHEK10.98490222
59TEC0.93708539
60MAP2K60.89313934
61KDR0.89312753
62IRAK30.88420712
63EIF2AK20.87613400
64MAP3K30.85922185
65NME10.85186109
66FLT30.82946529
67BRD40.81540744
68PIM10.81264325
69ERBB40.73080256
70ATM0.72373335
71CSNK2A10.71872972
72BRAF0.69298086
73CSNK2A20.67682852
74CDK20.67058156
75IRAK40.66324654
76FGFR10.65593964
77PDK20.65173650
78MAP3K110.64946805
79SCYL20.60456712
80MST1R0.59250540
81PDK30.57646247
82PDK40.57646247
83BTK0.54069460
84MET0.53218435
85MAPKAPK30.52112361
86TNIK0.50544949
87LATS10.50021577
88CDK60.48762250
89CDK10.47433174
90PAK10.46986820
91RPS6KA50.46943507
92CLK10.46305854
93CDK90.43766973
94BMX0.42139420
95PRKCI0.42100819
96MELK0.39134785
97TAOK20.38940969
98MAPK110.38229833
99AKT20.37820845
100LATS20.37255206
101ALK0.36952092
102PINK10.36592048
103PIM20.36499168
104YES10.36011700
105STK38L0.35719357
106BMPR1B0.34624301
107PRKDC0.33654042
108CDK190.33422087
109LRRK20.32174592
110DAPK10.29717332
111TXK0.27933301
112STK240.27365380
113NEK90.26874352
114CSF1R0.26107397
115IKBKB0.25242222
116ABL20.24944305
117BCR0.24691738
118KIT0.24687227
119NLK0.24416619
120LYN0.22792359
121ZAP700.21992704
122FGR0.21329597
123PNCK0.19918721
124CSNK1E0.19583890
125CDK180.16993817
126MAPK140.16446169
127CDK11A0.16125298
128PLK20.16109227
129CDK150.15089455

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.06574925
2Mismatch repair_Homo sapiens_hsa034304.38218252
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.57003630
4Ribosome_Homo sapiens_hsa030103.50937655
5RNA polymerase_Homo sapiens_hsa030203.33369799
6Proteasome_Homo sapiens_hsa030503.24693391
7Base excision repair_Homo sapiens_hsa034103.03049367
8Spliceosome_Homo sapiens_hsa030402.98251253
9Homologous recombination_Homo sapiens_hsa034402.97726168
10RNA transport_Homo sapiens_hsa030132.75789137
11Nucleotide excision repair_Homo sapiens_hsa034202.74117546
12One carbon pool by folate_Homo sapiens_hsa006702.64935442
13Pyrimidine metabolism_Homo sapiens_hsa002402.64023964
14Cell cycle_Homo sapiens_hsa041102.40296393
15Fanconi anemia pathway_Homo sapiens_hsa034602.21743285
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.21725090
17RNA degradation_Homo sapiens_hsa030181.95291062
18Basal transcription factors_Homo sapiens_hsa030221.81252050
19Non-homologous end-joining_Homo sapiens_hsa034501.75996914
20Vitamin B6 metabolism_Homo sapiens_hsa007501.58406081
21Folate biosynthesis_Homo sapiens_hsa007901.47825082
22Purine metabolism_Homo sapiens_hsa002301.45431113
23Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.38874348
24p53 signaling pathway_Homo sapiens_hsa041151.26947066
25mRNA surveillance pathway_Homo sapiens_hsa030151.20268480
26Cysteine and methionine metabolism_Homo sapiens_hsa002701.17211646
27Pentose phosphate pathway_Homo sapiens_hsa000301.15614863
28Biosynthesis of amino acids_Homo sapiens_hsa012301.14563310
29Steroid biosynthesis_Homo sapiens_hsa001001.12502292
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.11885712
31Sulfur relay system_Homo sapiens_hsa041221.09870169
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.08484662
33Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.06440732
34Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.06073384
35Fatty acid elongation_Homo sapiens_hsa000621.05438782
36Drug metabolism - other enzymes_Homo sapiens_hsa009831.03254361
37Epstein-Barr virus infection_Homo sapiens_hsa051691.00707252
38Selenocompound metabolism_Homo sapiens_hsa004500.99313498
39Carbon metabolism_Homo sapiens_hsa012000.97565209
40Huntingtons disease_Homo sapiens_hsa050160.90177907
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.86730264
42Parkinsons disease_Homo sapiens_hsa050120.85329367
43Systemic lupus erythematosus_Homo sapiens_hsa053220.84885515
44Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.84332166
45Cyanoamino acid metabolism_Homo sapiens_hsa004600.83078503
46Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.78961125
47Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.75141530
48Protein export_Homo sapiens_hsa030600.73165164
49Glutathione metabolism_Homo sapiens_hsa004800.71590254
50Antigen processing and presentation_Homo sapiens_hsa046120.71060771
51Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.69990093
52Herpes simplex infection_Homo sapiens_hsa051680.69844873
53Oocyte meiosis_Homo sapiens_hsa041140.62190135
54Oxidative phosphorylation_Homo sapiens_hsa001900.62110931
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.60153827
56Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.59267096
57Fructose and mannose metabolism_Homo sapiens_hsa000510.58485689
58Legionellosis_Homo sapiens_hsa051340.55311037
59Lysine degradation_Homo sapiens_hsa003100.54388210
60Viral carcinogenesis_Homo sapiens_hsa052030.51835176
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.49830263
62Metabolic pathways_Homo sapiens_hsa011000.49172499
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.46953999
64Fatty acid metabolism_Homo sapiens_hsa012120.44322857
65HTLV-I infection_Homo sapiens_hsa051660.42660435
66Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.42057122
67Basal cell carcinoma_Homo sapiens_hsa052170.40425668
68Propanoate metabolism_Homo sapiens_hsa006400.40341876
69Arginine and proline metabolism_Homo sapiens_hsa003300.36958887
70Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.36449967
71Hippo signaling pathway_Homo sapiens_hsa043900.36086576
72Thyroid cancer_Homo sapiens_hsa052160.34794033
73Galactose metabolism_Homo sapiens_hsa000520.34296615
74Adherens junction_Homo sapiens_hsa045200.33425418
75TGF-beta signaling pathway_Homo sapiens_hsa043500.33397678
76Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.32555033
77Bladder cancer_Homo sapiens_hsa052190.32231835
78Central carbon metabolism in cancer_Homo sapiens_hsa052300.29606000
79Pyruvate metabolism_Homo sapiens_hsa006200.29321376
80Prostate cancer_Homo sapiens_hsa052150.29285607
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.29050444
82Wnt signaling pathway_Homo sapiens_hsa043100.28894305
83Vitamin digestion and absorption_Homo sapiens_hsa049770.28255823
84Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.26192997
85Primary immunodeficiency_Homo sapiens_hsa053400.26183066
86Arachidonic acid metabolism_Homo sapiens_hsa005900.25702142
87Colorectal cancer_Homo sapiens_hsa052100.25049523
88N-Glycan biosynthesis_Homo sapiens_hsa005100.24612302
89Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.24556599
90Peroxisome_Homo sapiens_hsa041460.22934024
91Transcriptional misregulation in cancer_Homo sapiens_hsa052020.22005381
92NOD-like receptor signaling pathway_Homo sapiens_hsa046210.20500514
93beta-Alanine metabolism_Homo sapiens_hsa004100.19743659
94Alzheimers disease_Homo sapiens_hsa050100.19336538
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.19021864
96Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.18964577
97Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.18939107
98Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.18747080
99NF-kappa B signaling pathway_Homo sapiens_hsa040640.18282483
100Apoptosis_Homo sapiens_hsa042100.18119213
101Hedgehog signaling pathway_Homo sapiens_hsa043400.18070329
102HIF-1 signaling pathway_Homo sapiens_hsa040660.16671669
103Pentose and glucuronate interconversions_Homo sapiens_hsa000400.16285885
104Linoleic acid metabolism_Homo sapiens_hsa005910.16226947
105Other glycan degradation_Homo sapiens_hsa005110.15991808
106Hematopoietic cell lineage_Homo sapiens_hsa046400.14948703
107Small cell lung cancer_Homo sapiens_hsa052220.14605151
108Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.14203950
109Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.14202912
110Measles_Homo sapiens_hsa051620.14064999
111Fatty acid degradation_Homo sapiens_hsa000710.13351852
112Alcoholism_Homo sapiens_hsa050340.12962736
113Fat digestion and absorption_Homo sapiens_hsa049750.12409986
114Non-small cell lung cancer_Homo sapiens_hsa052230.11453647
115Sulfur metabolism_Homo sapiens_hsa009200.10877048
116Chronic myeloid leukemia_Homo sapiens_hsa052200.10664863
117MicroRNAs in cancer_Homo sapiens_hsa052060.10106320
118Influenza A_Homo sapiens_hsa051640.06789330
119Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.04173035
120alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.03592783
121RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.03422125
122Shigellosis_Homo sapiens_hsa051310.03419259
123Regulation of autophagy_Homo sapiens_hsa041400.03295219

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