MIA3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)5.81563631
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.81563631
3iron ion import (GO:0097286)5.75563971
4L-phenylalanine metabolic process (GO:0006558)5.32212050
5erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.32212050
6cytoplasmic mRNA processing body assembly (GO:0033962)5.16913230
7Golgi transport vesicle coating (GO:0048200)4.87097284
8COPI coating of Golgi vesicle (GO:0048205)4.87097284
9aromatic amino acid family catabolic process (GO:0009074)4.73190175
10nuclear pore complex assembly (GO:0051292)4.54467562
11insulin-like growth factor receptor signaling pathway (GO:0048009)4.35247166
12protein carboxylation (GO:0018214)4.20751766
13peptidyl-glutamic acid carboxylation (GO:0017187)4.20751766
14biotin metabolic process (GO:0006768)4.18728531
15intestinal cholesterol absorption (GO:0030299)4.15499190
16triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.11216313
17nuclear pore organization (GO:0006999)4.00844694
18alpha-linolenic acid metabolic process (GO:0036109)4.00350616
19COPII vesicle coating (GO:0048208)3.93677671
20bile acid biosynthetic process (GO:0006699)3.92969460
21import into cell (GO:0098657)3.90208585
22complement activation, alternative pathway (GO:0006957)3.87909187
23high-density lipoprotein particle remodeling (GO:0034375)3.84474284
24sulfur amino acid catabolic process (GO:0000098)3.83180270
25tyrosine metabolic process (GO:0006570)3.83168701
26urea cycle (GO:0000050)3.82469257
27urea metabolic process (GO:0019627)3.82469257
28negative regulation of fibrinolysis (GO:0051918)3.80535778
29positive regulation of transcription from RNA polymerase III promoter (GO:0045945)3.78408992
30regulation of protein activation cascade (GO:2000257)3.78348074
31regulation of RNA export from nucleus (GO:0046831)3.77984778
32regulation of fibrinolysis (GO:0051917)3.77280457
33tryptophan catabolic process (GO:0006569)3.76569797
34indole-containing compound catabolic process (GO:0042436)3.76569797
35indolalkylamine catabolic process (GO:0046218)3.76569797
36tryptophan metabolic process (GO:0006568)3.74994458
37kynurenine metabolic process (GO:0070189)3.71030043
38cysteine metabolic process (GO:0006534)3.69860437
39homocysteine metabolic process (GO:0050667)3.69238460
40bile acid metabolic process (GO:0008206)3.61868793
41maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.58031173
42regulation of complement activation (GO:0030449)3.57996821
43triglyceride homeostasis (GO:0070328)3.52259675
44acylglycerol homeostasis (GO:0055090)3.52259675
45histone H3-K36 demethylation (GO:0070544)3.51324244
46reverse cholesterol transport (GO:0043691)3.48339994
47nitrogen cycle metabolic process (GO:0071941)3.47858105
48glyoxylate metabolic process (GO:0046487)3.47291710
49carnitine shuttle (GO:0006853)3.47253798
50monoubiquitinated protein deubiquitination (GO:0035520)3.43715781
51aromatic amino acid family metabolic process (GO:0009072)3.42914142
52endocrine pancreas development (GO:0031018)3.42798308
53negative regulation of complement activation (GO:0045916)3.42553732
54negative regulation of glycogen biosynthetic process (GO:0045719)3.41351911
55fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.40796703
56cellular response to ethanol (GO:0071361)3.39660576
57bile acid and bile salt transport (GO:0015721)3.38861621
58coenzyme catabolic process (GO:0009109)3.38819561
59regulation of cholesterol homeostasis (GO:2000188)3.28248965
60regulation of nucleobase-containing compound transport (GO:0032239)3.27944972
61histone H3-K9 demethylation (GO:0033169)3.26028365
62intestinal absorption (GO:0050892)3.25777288
63lysine catabolic process (GO:0006554)3.25147062
64lysine metabolic process (GO:0006553)3.25147062
65branching involved in prostate gland morphogenesis (GO:0060442)3.23378834
66retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.21992977
67Golgi to endosome transport (GO:0006895)3.21719264
68activation of signaling protein activity involved in unfolded protein response (GO:0006987)3.20978536
69plasma lipoprotein particle remodeling (GO:0034369)3.20789718
70protein-lipid complex remodeling (GO:0034368)3.20789718
71macromolecular complex remodeling (GO:0034367)3.20789718
72phospholipid efflux (GO:0033700)3.19909187
73cellular ketone body metabolic process (GO:0046950)3.18450197
74phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.16714862
75regulation of triglyceride catabolic process (GO:0010896)3.15883401
76cholesterol efflux (GO:0033344)3.13946024
77histone lysine demethylation (GO:0070076)3.12872477
78Golgi organization (GO:0007030)3.12421688
79cellular modified amino acid catabolic process (GO:0042219)3.11799610
804-hydroxyproline metabolic process (GO:0019471)3.11785585
81pore complex assembly (GO:0046931)3.11590166
82UDP-N-acetylglucosamine metabolic process (GO:0006047)3.11376619
83ER overload response (GO:0006983)3.10477408
84positive regulation of fatty acid beta-oxidation (GO:0032000)3.08826050
85plasma lipoprotein particle clearance (GO:0034381)3.08573251
86histone H3-K4 trimethylation (GO:0080182)3.08295542
87alpha-amino acid catabolic process (GO:1901606)3.07662241
88embryonic retina morphogenesis in camera-type eye (GO:0060059)3.06089184
89indolalkylamine metabolic process (GO:0006586)3.05152584
90drug transmembrane transport (GO:0006855)3.04839653
91protein retention in ER lumen (GO:0006621)3.03849055
92regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.03567808
93short-chain fatty acid metabolic process (GO:0046459)3.03358375
94phospholipid homeostasis (GO:0055091)3.02675225
95serine family amino acid catabolic process (GO:0009071)3.02553025
96fatty acid transmembrane transport (GO:1902001)3.02332720
97glutamate metabolic process (GO:0006536)3.01346707
98negative regulation of protein activation cascade (GO:2000258)3.00851583
99histone demethylation (GO:0016577)3.00293700
100regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.99281366
101positive regulation of nuclease activity (GO:0032075)2.98037469
102cellular amino acid catabolic process (GO:0009063)2.95397005
103endocrine hormone secretion (GO:0060986)2.95200164
104establishment of protein localization to Golgi (GO:0072600)2.95165480
105regulation of cholesterol esterification (GO:0010872)2.93489792
106amino-acid betaine metabolic process (GO:0006577)2.92294095
107interkinetic nuclear migration (GO:0022027)2.91855804
108drug catabolic process (GO:0042737)2.89670305
109positive regulation of glycolytic process (GO:0045821)2.89049678
110macroautophagy (GO:0016236)2.87815515
111negative regulation of lipase activity (GO:0060192)2.87709905
112negative regulation of sterol transport (GO:0032372)2.84395429
113negative regulation of cholesterol transport (GO:0032375)2.84395429
114early endosome to late endosome transport (GO:0045022)2.83238407
115protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.81957133
116transcytosis (GO:0045056)2.81933681
117cellular glucuronidation (GO:0052695)2.81840892
118valine metabolic process (GO:0006573)2.81217738
119positive regulation of lipid catabolic process (GO:0050996)2.80321109
120lipoprotein metabolic process (GO:0042157)2.79362032
121endoplasmic reticulum unfolded protein response (GO:0030968)2.79321367
122regulation of bile acid biosynthetic process (GO:0070857)2.78198504
123exocrine pancreas development (GO:0031017)2.77397504
124ketone body metabolic process (GO:1902224)2.77273033
125protein targeting to vacuole (GO:0006623)2.76794583
126protein targeting to lysosome (GO:0006622)2.76794583
127establishment of protein localization to vacuole (GO:0072666)2.76794583
128protein targeting to Golgi (GO:0000042)2.76736711
129carnitine transmembrane transport (GO:1902603)2.75288012
130fatty acid oxidation (GO:0019395)2.74833345
131ER-nucleus signaling pathway (GO:0006984)2.74722339
132cellular response to unfolded protein (GO:0034620)2.73520034
133vesicle coating (GO:0006901)2.73407376
134histone H3-K4 methylation (GO:0051568)2.73225904
135Golgi to plasma membrane transport (GO:0006893)2.72922555
136fibrinolysis (GO:0042730)2.72716047
137peptide hormone processing (GO:0016486)2.71564199
138plasma lipoprotein particle assembly (GO:0034377)2.71029103
139negative regulation of glycogen metabolic process (GO:0070874)2.70590943
140retrograde transport, vesicle recycling within Golgi (GO:0000301)2.69983164
141complement activation, classical pathway (GO:0006958)2.69427481
142regulation of NFAT protein import into nucleus (GO:0051532)2.69127195
143regulation of cholesterol biosynthetic process (GO:0045540)2.68332330
144lipid oxidation (GO:0034440)2.68174943
145prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.65075384
146carnitine transport (GO:0015879)2.64859066
147amino-acid betaine transport (GO:0015838)2.64859066
148epoxygenase P450 pathway (GO:0019373)2.63795202
149regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.62067742
150protein demethylation (GO:0006482)2.60786423
151protein dealkylation (GO:0008214)2.60786423
152intracellular lipid transport (GO:0032365)2.60554682
153mitotic sister chromatid cohesion (GO:0007064)2.59067115
154coronary vasculature morphogenesis (GO:0060977)2.58271830
155endoplasmic reticulum organization (GO:0007029)2.57728533
156stress granule assembly (GO:0034063)2.57383459
157mRNA modification (GO:0016556)2.56275261
158omega-hydroxylase P450 pathway (GO:0097267)2.54842761
159phospholipid translocation (GO:0045332)2.53462737
160lipid translocation (GO:0034204)2.53462737
161NLS-bearing protein import into nucleus (GO:0006607)2.52057544
162regulation of protein polyubiquitination (GO:1902914)2.48543493
163peptidyl-lysine dimethylation (GO:0018027)2.47719565
164anterior/posterior axis specification, embryo (GO:0008595)2.45732032
165regulation of ARF protein signal transduction (GO:0032012)2.45603815
166intestinal epithelial cell development (GO:0060576)2.45359218
167intra-Golgi vesicle-mediated transport (GO:0006891)2.45132267
168linoleic acid metabolic process (GO:0043651)2.44459453
169peptidyl-lysine trimethylation (GO:0018023)2.44225826
170regulation of endothelial cell chemotaxis (GO:2001026)2.42211835
171positive regulation of macroautophagy (GO:0016239)2.42046519
172negative regulation of glucose import (GO:0046325)2.41455183
173negative regulation of fatty acid biosynthetic process (GO:0045717)2.40572214
174very-low-density lipoprotein particle assembly (GO:0034379)2.37664336
175positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.37519112
176negative regulation of humoral immune response (GO:0002921)2.36834453
177regulation of clathrin-mediated endocytosis (GO:2000369)2.32262018
178quaternary ammonium group transport (GO:0015697)2.31435674
179ovulation from ovarian follicle (GO:0001542)2.31386966
180pre-miRNA processing (GO:0031054)2.30368221
181peptidyl-threonine modification (GO:0018210)2.27944202

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse6.51833396
2RXR_22158963_ChIP-Seq_LIVER_Mouse5.09801044
3LXR_22158963_ChIP-Seq_LIVER_Mouse4.39789784
4PPARA_22158963_ChIP-Seq_LIVER_Mouse4.22533453
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.84957240
6EGR1_23403033_ChIP-Seq_LIVER_Mouse3.34063084
7FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.31382879
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.00613769
9SALL1_21062744_ChIP-ChIP_HESCs_Human2.70095747
10GATA1_22025678_ChIP-Seq_K562_Human2.66354823
11SMAD_19615063_ChIP-ChIP_OVARY_Human2.56701157
12CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.49246522
13PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.22100014
14AR_21909140_ChIP-Seq_LNCAP_Human2.19411029
15WT1_19549856_ChIP-ChIP_CCG9911_Human1.99100906
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.97931617
17NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.96906248
18FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.89177449
19* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.80761310
20AR_21572438_ChIP-Seq_LNCaP_Human1.80137736
21RBPJ_22232070_ChIP-Seq_NCS_Mouse1.79733021
22FOXA2_19822575_ChIP-Seq_HepG2_Human1.74853716
23EGR1_19374776_ChIP-ChIP_THP-1_Human1.74293797
24CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.70251429
25CLOCK_20551151_ChIP-Seq_293T_Human1.67885674
26* CHD1_26751641_Chip-Seq_LNCaP_Human1.67310324
27TCF4_18268006_ChIP-ChIP_LS174T_Human1.66858711
28CTNNB1_20460455_ChIP-Seq_HCT116_Human1.66709541
29TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.52684444
30ZNF217_24962896_ChIP-Seq_MCF-7_Human1.44440109
31PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.42916950
32* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.40910240
33TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40891533
34TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.38565514
35STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.38229334
36NRF2_20460467_ChIP-Seq_MEFs_Mouse1.37616376
37NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.37616376
38PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.37615476
39FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.36650393
40IGF1R_20145208_ChIP-Seq_DFB_Human1.36502074
41* PIAS1_25552417_ChIP-Seq_VCAP_Human1.36350793
42BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.35513070
43TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.34760433
44ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.33953664
45CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.33826218
46* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.30864325
47SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29196312
48ZFP57_27257070_Chip-Seq_ESCs_Mouse1.27034543
49TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.26905013
50TP53_16413492_ChIP-PET_HCT116_Human1.26835180
51AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.25246368
52CDX2_19796622_ChIP-Seq_MESCs_Mouse1.24575949
53* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.23245000
54PKCTHETA_26484144_Chip-Seq_BREAST_Human1.23080205
55ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.22948994
56SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22518248
57NR3C1_23031785_ChIP-Seq_PC12_Mouse1.22232256
58EZH2_27294783_Chip-Seq_NPCs_Mouse1.21490914
59SALL4_18804426_ChIP-ChIP_XEN_Mouse1.20309602
60YAP1_20516196_ChIP-Seq_MESCs_Mouse1.18866158
61NANOG_18555785_Chip-Seq_ESCs_Mouse1.17382549
62GATA6_25053715_ChIP-Seq_YYC3_Human1.16505656
63GBX2_23144817_ChIP-Seq_PC3_Human1.15940201
64ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.15884235
65E2F1_18555785_Chip-Seq_ESCs_Mouse1.15357417
66HTT_18923047_ChIP-ChIP_STHdh_Human1.15230236
67PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.13055115
68SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.11505320
69ESR1_21235772_ChIP-Seq_MCF-7_Human1.08274232
70NFE2_27457419_Chip-Seq_LIVER_Mouse1.08175435
71* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.07578287
72ER_23166858_ChIP-Seq_MCF-7_Human1.06184930
73BRD4_25478319_ChIP-Seq_HGPS_Human1.04916267
74* HNF4A_19822575_ChIP-Seq_HepG2_Human1.04802541
75TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.04130090
76BCAT_22108803_ChIP-Seq_LS180_Human1.03292892
77SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.02889329
78SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.02889329
79CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.02888514
80CRX_20693478_ChIP-Seq_RETINA_Mouse1.02282978
81FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.01050949
82ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.00288725
83EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99578528
84OCT4_21477851_ChIP-Seq_ESCs_Mouse0.99258723
85DROSHA_22980978_ChIP-Seq_HELA_Human0.97507796
86STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.97393084
87BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.96626589
88POU3F2_20337985_ChIP-ChIP_501MEL_Human0.96448266
89CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.96331978
90FOXA1_25552417_ChIP-Seq_VCAP_Human0.95763705
91ESR2_21235772_ChIP-Seq_MCF-7_Human0.95446239
92SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.94985211
93TRIM28_21343339_ChIP-Seq_HEK293_Human0.93598662
94HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.92511724
95SMAD4_21799915_ChIP-Seq_A2780_Human0.92068184
96GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.90415643
97STAT3_23295773_ChIP-Seq_U87_Human0.90082963
98TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89729243
99AHR_22903824_ChIP-Seq_MCF-7_Human0.89422204
100PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.89042855
101FOXO3_23340844_ChIP-Seq_DLD1_Human0.89002899
102SOX2_21211035_ChIP-Seq_LN229_Gbm0.88021760
103ARNT_22903824_ChIP-Seq_MCF-7_Human0.86340409
104GATA4_25053715_ChIP-Seq_YYC3_Human0.85888057
105NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85195710
106MTF2_20144788_ChIP-Seq_MESCs_Mouse0.84062494
107MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.83807534
108EP300_21415370_ChIP-Seq_HL-1_Mouse0.82625819
109SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.82512220
110SOX2_20726797_ChIP-Seq_SW620_Human0.81811528
111NFIB_24661679_ChIP-Seq_LUNG_Mouse0.81248603
112RXR_22108803_ChIP-Seq_LS180_Human0.81110919
113TP63_23658742_ChIP-Seq_EP156T_Human0.80955754
114EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.79121507
115* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.77237650
116FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.76981695
117CDX2_22108803_ChIP-Seq_LS180_Human0.76435251
118OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.76182627
119ESR1_20079471_ChIP-ChIP_T-47D_Human0.74218497
120FOXM1_26456572_ChIP-Seq_MCF-7_Human0.74155734
121SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.72941319
122GATA1_19941826_ChIP-Seq_K562_Human0.72512542
123TCF4_23295773_ChIP-Seq_U87_Human0.71808383
124AR_25329375_ChIP-Seq_VCAP_Human0.71629343
125ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.71349425
126TOP2B_26459242_ChIP-Seq_MCF-7_Human0.70664250
127CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.70357898
128SMAD4_21741376_ChIP-Seq_HESCs_Human0.70079544
129REST_21632747_ChIP-Seq_MESCs_Mouse0.69784428
130AR_19668381_ChIP-Seq_PC3_Human0.69678761
131PPAR_26484153_Chip-Seq_NCI-H1993_Human0.69210776
132SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.68206292
133TBX20_22328084_ChIP-Seq_HEART_Mouse0.67990468
134TBX20_22080862_ChIP-Seq_HEART_Mouse0.67990468
135WT1_25993318_ChIP-Seq_PODOCYTE_Human0.67914604
136P300_19829295_ChIP-Seq_ESCs_Human0.67856840
137GATA3_24758297_ChIP-Seq_MCF-7_Human0.67583675
138SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.67333693
139SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.67312688
140CTBP2_25329375_ChIP-Seq_LNCAP_Human0.67033629
141CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.66988684
142SOX9_24532713_ChIP-Seq_HFSC_Mouse0.66428626
143GATA2_21666600_ChIP-Seq_HMVEC_Human0.66062040
144CJUN_26792858_Chip-Seq_BT549_Human0.65946697
145SMAD4_21741376_ChIP-Seq_EPCs_Human0.65434656

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002009_preneoplasia6.20862272
2MP0002139_abnormal_hepatobiliary_system6.20470667
3MP0005360_urolithiasis5.33264798
4MP0005365_abnormal_bile_salt5.17035456
5MP0005085_abnormal_gallbladder_physiolo4.92119828
6MP0003252_abnormal_bile_duct3.93441557
7MP0003195_calcinosis3.79360278
8MP0008057_abnormal_DNA_replication3.70991088
9MP0008875_abnormal_xenobiotic_pharmacok3.60510839
10MP0002166_altered_tumor_susceptibility3.39329881
11MP0004858_abnormal_nervous_system2.96926208
12MP0001666_abnormal_nutrient_absorption2.87968488
13MP0010352_gastrointestinal_tract_polyps2.80289628
14MP0003868_abnormal_feces_composition2.72547213
15MP0004233_abnormal_muscle_weight2.65226794
16MP0010329_abnormal_lipoprotein_level2.64179085
17MP0009780_abnormal_chondrocyte_physiolo2.64156266
18MP0005083_abnormal_biliary_tract2.63990602
19MP0002006_tumorigenesis2.38004028
20MP0003806_abnormal_nucleotide_metabolis2.32860923
21MP0004043_abnormal_pH_regulation2.25625703
22MP0000013_abnormal_adipose_tissue2.13976068
23MP0002877_abnormal_melanocyte_morpholog2.13846287
24MP0000569_abnormal_digit_pigmentation2.10828939
25MP0002693_abnormal_pancreas_physiology2.03794797
26MP0005332_abnormal_amino_acid2.02518989
27MP0002837_dystrophic_cardiac_calcinosis2.00277723
28MP0002909_abnormal_adrenal_gland1.99990731
29MP0005220_abnormal_exocrine_pancreas1.98373939
30MP0005076_abnormal_cell_differentiation1.98290144
31MP0001944_abnormal_pancreas_morphology1.97176829
32MP0002118_abnormal_lipid_homeostasis1.91890546
33MP0009840_abnormal_foam_cell1.90706617
34MP0002138_abnormal_hepatobiliary_system1.80799541
35MP0002078_abnormal_glucose_homeostasis1.79126528
36MP0000609_abnormal_liver_physiology1.68656917
37MP0003283_abnormal_digestive_organ1.67837244
38MP0003890_abnormal_embryonic-extraembry1.63503813
39MP0010386_abnormal_urinary_bladder1.55810843
40MP0003191_abnormal_cellular_cholesterol1.48990887
41MP0003705_abnormal_hypodermis_morpholog1.45336512
42MP0003787_abnormal_imprinting1.41824776
43MP0009643_abnormal_urine_homeostasis1.41147531
44MP0010234_abnormal_vibrissa_follicle1.39040657
45MP0004019_abnormal_vitamin_homeostasis1.38562325
46MP0003300_gastrointestinal_ulcer1.35194525
47MP0000003_abnormal_adipose_tissue1.33533250
48MP0005503_abnormal_tendon_morphology1.28002231
49MP0005319_abnormal_enzyme/_coenzyme1.26842456
50MP0003123_paternal_imprinting1.26451331
51MP0004264_abnormal_extraembryonic_tissu1.25750294
52MP0004036_abnormal_muscle_relaxation1.23558847
53MP0009697_abnormal_copulation1.21724055
54MP0002896_abnormal_bone_mineralization1.21234964
55MP0002928_abnormal_bile_duct1.20202998
56MP0005379_endocrine/exocrine_gland_phen1.18622208
57MP0003315_abnormal_perineum_morphology1.18567194
58MP0003091_abnormal_cell_migration1.17839453
59MP0003941_abnormal_skin_development1.17218916
60MP0008438_abnormal_cutaneous_collagen1.15823073
61MP0005310_abnormal_salivary_gland1.15750666
62MP0003221_abnormal_cardiomyocyte_apopto1.15351815
63MP0005535_abnormal_body_temperature1.13524404
64MP0000537_abnormal_urethra_morphology1.12051733
65MP0005058_abnormal_lysosome_morphology1.10513416
66MP0001765_abnormal_ion_homeostasis1.10440858
67MP0002876_abnormal_thyroid_physiology1.09834544
68MP0005670_abnormal_white_adipose1.09447035
69MP0001764_abnormal_homeostasis1.06672038
70MP0003183_abnormal_peptide_metabolism1.03326558
71MP0000627_abnormal_mammary_gland1.02727255
72MP0003121_genomic_imprinting1.02633744
73MP0003950_abnormal_plasma_membrane1.02359223
74MP0005395_other_phenotype1.01661288
75MP0005636_abnormal_mineral_homeostasis1.01228926
76MP0003632_abnormal_nervous_system1.01083909
77MP0004130_abnormal_muscle_cell1.01044270
78MP0005409_darkened_coat_color1.00981413
79MP0005451_abnormal_body_composition1.00383184
80MP0003045_fibrosis0.99662711
81MP0003953_abnormal_hormone_level0.98913022
82MP0005334_abnormal_fat_pad0.98425054
83MP0008961_abnormal_basal_metabolism0.94011030
84MP0005584_abnormal_enzyme/coenzyme_acti0.93556054
85MP0004084_abnormal_cardiac_muscle0.93334448
86MP0005448_abnormal_energy_balance0.93327244
87MP0001915_intracranial_hemorrhage0.92573661
88MP0004272_abnormal_basement_membrane0.91610879
89MP0009115_abnormal_fat_cell0.91539848
90MP0002168_other_aberrant_phenotype0.89871379
91MP0005375_adipose_tissue_phenotype0.88777548
92MP0001756_abnormal_urination0.88582408
93MP0002971_abnormal_brown_adipose0.88342733
94MP0002088_abnormal_embryonic_growth/wei0.88122920
95MP0002108_abnormal_muscle_morphology0.87014674
96MP0010307_abnormal_tumor_latency0.86742105
97MP0003984_embryonic_growth_retardation0.85693355
98MP0005408_hypopigmentation0.85192620
99MP0005621_abnormal_cell_physiology0.84817898
100MP0003959_abnormal_lean_body0.83839905
101MP0009642_abnormal_blood_homeostasis0.83543168
102MP0000371_diluted_coat_color0.82424794
103MP0003566_abnormal_cell_adhesion0.81048808
104MP0000604_amyloidosis0.79670254
105MP0000598_abnormal_liver_morphology0.78387018
106MP0000678_abnormal_parathyroid_gland0.78368736
107MP0009703_decreased_birth_body0.78166682
108MP0000733_abnormal_muscle_development0.77786853
109MP0004197_abnormal_fetal_growth/weight/0.76289294
110MP0003329_amyloid_beta_deposits0.76158315
111MP0002086_abnormal_extraembryonic_tissu0.75674398
112MP0004782_abnormal_surfactant_physiolog0.75554754
113MP0000230_abnormal_systemic_arterial0.73528501
114MP0005084_abnormal_gallbladder_morpholo0.73363347
115MP0000639_abnormal_adrenal_gland0.72680619
116MP0001984_abnormal_olfaction0.72670729
117MP0000538_abnormal_urinary_bladder0.71501631
118MP0006138_congestive_heart_failure0.70919314
119MP0005164_abnormal_response_to0.67398186
120MP0005666_abnormal_adipose_tissue0.66156060
121MP0000432_abnormal_head_morphology0.65732757
122MP0003172_abnormal_lysosome_physiology0.65506322
123MP0001661_extended_life_span0.64768263
124MP0001672_abnormal_embryogenesis/_devel0.63054411
125MP0005380_embryogenesis_phenotype0.63054411
126MP0003879_abnormal_hair_cell0.62017403
127MP0008775_abnormal_heart_ventricle0.61303797
128MP0005645_abnormal_hypothalamus_physiol0.58467935
129MP0005646_abnormal_pituitary_gland0.58206634
130MP0006054_spinal_hemorrhage0.57970529
131MP0009384_cardiac_valve_regurgitation0.55043698
132MP0003656_abnormal_erythrocyte_physiolo0.54291472
133MP0005187_abnormal_penis_morphology0.54146143
134MP0000613_abnormal_salivary_gland0.52478307
135MP0000462_abnormal_digestive_system0.51945125
136MP0009763_increased_sensitivity_to0.51760677
137MP0003690_abnormal_glial_cell0.51707663
138MP0002060_abnormal_skin_morphology0.51705852
139MP0002295_abnormal_pulmonary_circulatio0.51520918
140MP0005275_abnormal_skin_tensile0.50681354
141MP0004185_abnormal_adipocyte_glucose0.47384341
142MP0005647_abnormal_sex_gland0.47311011
143MP0001502_abnormal_circadian_rhythm0.46670513
144MP0002638_abnormal_pupillary_reflex0.46071725
145MP0001881_abnormal_mammary_gland0.45816051
146MP0003633_abnormal_nervous_system0.44805773
147MP0002069_abnormal_eating/drinking_beha0.44558500
148MP0005248_abnormal_Harderian_gland0.43709229
149MP0001299_abnormal_eye_distance/0.43186375
150MP0002090_abnormal_vision0.42576123
151MP0010368_abnormal_lymphatic_system0.42386269

Predicted human phenotypes

RankGene SetZ-score
1Intrahepatic cholestasis (HP:0001406)5.61773202
2Abnormality of aromatic amino acid family metabolism (HP:0004338)5.58490923
3Hypoglycemic coma (HP:0001325)5.26617831
4Deep venous thrombosis (HP:0002625)5.17914945
5Hyperinsulinemic hypoglycemia (HP:0000825)5.06490623
6Hypoglycemic seizures (HP:0002173)4.80632840
7Abnormality of monocarboxylic acid metabolism (HP:0010996)4.72687724
8Prolonged partial thromboplastin time (HP:0003645)4.68276422
9Xanthomatosis (HP:0000991)4.66137935
10Sparse lateral eyebrow (HP:0005338)4.47642802
11Abnormality of the intrinsic pathway (HP:0010989)4.32819406
12Abnormality of the common coagulation pathway (HP:0010990)4.32207367
13Ketoacidosis (HP:0001993)4.30174174
14Conjugated hyperbilirubinemia (HP:0002908)4.29763664
15Ketosis (HP:0001946)4.20986953
16Hyperglycemia (HP:0003074)4.06973055
17Hypobetalipoproteinemia (HP:0003563)3.99141849
18Papillary thyroid carcinoma (HP:0002895)3.98947387
19Symptomatic seizures (HP:0011145)3.93613451
20Complement deficiency (HP:0004431)3.81588199
21Hyperlipoproteinemia (HP:0010980)3.74401630
22Neonatal hypoglycemia (HP:0001998)3.65670603
23Lip pit (HP:0100267)3.51795327
24Epidermoid cyst (HP:0200040)3.42605348
25Fat malabsorption (HP:0002630)3.38580416
26Skin nodule (HP:0200036)3.36799386
27Dysmetric saccades (HP:0000641)3.28134547
28Abnormality of the fingertips (HP:0001211)3.24824045
29Insulin-resistant diabetes mellitus (HP:0000831)3.22432808
30Hypolipoproteinemia (HP:0010981)3.21976381
31Abnormality of the pancreatic islet cells (HP:0006476)3.20078214
32Abnormality of endocrine pancreas physiology (HP:0012093)3.20078214
33Joint hemorrhage (HP:0005261)3.14952208
34Hyperglycinemia (HP:0002154)3.14137145
35Hypoalphalipoproteinemia (HP:0003233)3.02824022
36Overgrowth (HP:0001548)3.00834201
37Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.00030547
38Pancreatic islet-cell hyperplasia (HP:0004510)2.99111352
39Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.97447831
40Abnormality of sulfur amino acid metabolism (HP:0004339)2.86819936
41Late onset (HP:0003584)2.79900184
42Abnormality of glutamine family amino acid metabolism (HP:0010902)2.79884819
43Macroorchidism (HP:0000053)2.78092507
44Hyperammonemia (HP:0001987)2.73521937
45Abnormality of complement system (HP:0005339)2.63860508
46Abnormality of methionine metabolism (HP:0010901)2.55942786
47Abnormality of aspartate family amino acid metabolism (HP:0010899)2.55332339
48Abnormality of serine family amino acid metabolism (HP:0010894)2.52655137
49Abnormality of glycine metabolism (HP:0010895)2.52655137
50Gonadotropin excess (HP:0000837)2.51812788
51Abnormality of purine metabolism (HP:0004352)2.51738413
52Hyperglycinuria (HP:0003108)2.49995353
53Myocardial infarction (HP:0001658)2.48743245
54Hypercholesterolemia (HP:0003124)2.46845668
55Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.45696450
56Gout (HP:0001997)2.45530009
57Anal stenosis (HP:0002025)2.41345887
58Generalized aminoaciduria (HP:0002909)2.40281621
59Narrow palate (HP:0000189)2.38788270
60Flat acetabular roof (HP:0003180)2.38614470
61Hyperbilirubinemia (HP:0002904)2.37492437
62Volvulus (HP:0002580)2.32860132
63Thyroid carcinoma (HP:0002890)2.30739991
64Protuberant abdomen (HP:0001538)2.30739387
65Mucopolysacchariduria (HP:0008155)2.30010883
66Urinary glycosaminoglycan excretion (HP:0003541)2.30010883
67Retinal atrophy (HP:0001105)2.29078470
68Mitral stenosis (HP:0001718)2.27969666
69Abnormality of the axillary hair (HP:0100134)2.26018124
70Abnormality of secondary sexual hair (HP:0009888)2.26018124
71Deep philtrum (HP:0002002)2.19478246
72Insulin resistance (HP:0000855)2.19345896
73Truncal obesity (HP:0001956)2.18866265
74Abnormality of fatty-acid metabolism (HP:0004359)2.18351304
75Coarse hair (HP:0002208)2.17205684
76Cubitus valgus (HP:0002967)2.16135519
77Large for gestational age (HP:0001520)2.15170110
78Abnormality of polysaccharide metabolism (HP:0011012)2.14879239
79Abnormality of glycosaminoglycan metabolism (HP:0004371)2.14879239
80Abnormality of mucopolysaccharide metabolism (HP:0011020)2.14879239
81Persistence of primary teeth (HP:0006335)2.14498195
82Hypochromic microcytic anemia (HP:0004840)2.14463692
83Steatorrhea (HP:0002570)2.13799608
84Curly hair (HP:0002212)2.13399574
85Hepatocellular carcinoma (HP:0001402)2.13345867
86Hyperventilation (HP:0002883)2.12654799
87Azoospermia (HP:0000027)2.12108624
88Heterotopia (HP:0002282)2.09863428
89Pheochromocytoma (HP:0002666)2.08818614
90Dysostosis multiplex (HP:0000943)2.07196973
91Pancreatitis (HP:0001733)2.05935151
92Acute myeloid leukemia (HP:0004808)2.05429432
93Abnormality of nucleobase metabolism (HP:0010932)2.03390209
94Irritability (HP:0000737)2.02661990
95Enlarged kidneys (HP:0000105)2.01612119
96Germ cell neoplasia (HP:0100728)1.99513929
97Hypoplastic nipples (HP:0002557)1.97871659
98Bifid scrotum (HP:0000048)1.97775267
99Acute hepatic failure (HP:0006554)1.97739372
100Genetic anticipation (HP:0003743)1.97731740
101Blue irides (HP:0000635)1.97537573
102Abdominal distention (HP:0003270)1.96830655
103Broad nasal tip (HP:0000455)1.96160084
104Abnormality of calcium-phosphate metabolism (HP:0100530)1.96130818
105Decreased circulating renin level (HP:0003351)1.95956582
106Sensorimotor neuropathy (HP:0007141)1.95376452
107Generalized hypopigmentation of hair (HP:0011358)1.94774317
108Metabolic acidosis (HP:0001942)1.94566737
109Relative macrocephaly (HP:0004482)1.94371772
110Elevated alkaline phosphatase (HP:0003155)1.93573347
111Abnormal foot bone ossification (HP:0010675)1.93322372
112Global brain atrophy (HP:0002283)1.92975330
113Arterial tortuosity (HP:0005116)1.92605467
114Advanced eruption of teeth (HP:0006288)1.92192051
115Back pain (HP:0003418)1.91760056
116Prostate neoplasm (HP:0100787)1.91476196
117Right ventricular cardiomyopathy (HP:0011663)1.90752911
118Abnormal enzyme/coenzyme activity (HP:0012379)1.90447389
119Termporal pattern (HP:0011008)1.90056885
120Insidious onset (HP:0003587)1.90056885
121Turricephaly (HP:0000262)1.89115169
122Long eyelashes (HP:0000527)1.88938895
123Abnormality of the phalanges of the hallux (HP:0010057)1.88147623
124Abnormality of the distal phalanx of the thumb (HP:0009617)1.87856964
125Fair hair (HP:0002286)1.87179107
126EEG with generalized epileptiform discharges (HP:0011198)1.86011056
127Lower limb hyperreflexia (HP:0002395)1.85569745
128Sandal gap (HP:0001852)1.85423086
129Abnormal tarsal ossification (HP:0008369)1.84071786
130Hypsarrhythmia (HP:0002521)1.83895867
131Abnormal gallbladder morphology (HP:0012437)1.83411744
132Scanning speech (HP:0002168)1.82277468
133Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.82118962
134Abnormal pancreas size (HP:0012094)1.81807071
135Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.81674959
136Glomerulonephritis (HP:0000099)1.80975545
137Subacute progressive viral hepatitis (HP:0006572)1.80600017
138Obstructive sleep apnea (HP:0002870)1.79866585
139Epileptiform EEG discharges (HP:0011182)1.79812168
140Capillary hemangiomas (HP:0005306)1.79288789
141Acanthocytosis (HP:0001927)1.78535143
142Abnormality of serum amino acid levels (HP:0003112)1.78365234
143Agitation (HP:0000713)1.78302717
144Cervical subluxation (HP:0003308)1.78283125
145Vertebral arch anomaly (HP:0008438)1.78215986
146Abnormality of alkaline phosphatase activity (HP:0004379)1.78213762
147Abnormality of the nasal septum (HP:0000419)1.77642844
148Tubulointerstitial nephritis (HP:0001970)1.76713691
149Vascular tortuosity (HP:0004948)1.76248067
150Abnormality of the parathyroid morphology (HP:0011766)1.76225016
151Menorrhagia (HP:0000132)1.76113055
152Gaze-evoked nystagmus (HP:0000640)1.76103540
153Papilledema (HP:0001085)1.75432798
154Laryngomalacia (HP:0001601)1.74507300
155Asymmetry of the thorax (HP:0001555)1.73943101
156Hypophosphatemia (HP:0002148)1.73483166
157Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.73167119
158Testicular neoplasm (HP:0010788)1.72867506
159Cystic hygroma (HP:0000476)1.72370286
160Open mouth (HP:0000194)1.71093018
161Aneurysm (HP:0002617)1.70738320
162Calf muscle hypertrophy (HP:0008981)1.70660611
163Low anterior hairline (HP:0000294)1.70585205
164Tapered finger (HP:0001182)1.68986674
165Impaired vibratory sensation (HP:0002495)1.68471839
166Hypoplastic labia majora (HP:0000059)1.67324192
167Hyperkalemia (HP:0002153)1.65164140
168Hypopigmentation of the fundus (HP:0007894)1.65121626
169Delayed CNS myelination (HP:0002188)1.65031529
170Ankyloglossia (HP:0010296)1.64450919
171Abnormality of the ischium (HP:0003174)1.64092480
172Abnormality of the epiphyses of the hand (HP:0005924)1.63953742
173Broad face (HP:0000283)1.62364689
174Alkalosis (HP:0001948)1.62362107
175Depressed nasal tip (HP:0000437)1.62241749
176Hypophosphatemic rickets (HP:0004912)1.60497672
177Hypoplasia of the odontoid process (HP:0003311)1.60322164
178Rickets (HP:0002748)1.58972542
179Abnormality of dicarboxylic acid metabolism (HP:0010995)1.58643947
180Dicarboxylic aciduria (HP:0003215)1.58643947
181Mitral valve prolapse (HP:0001634)1.58593387
182Death in childhood (HP:0003819)1.57846397
183Systemic lupus erythematosus (HP:0002725)1.57737240
184Abnormality of chromosome segregation (HP:0002916)1.56102442
185Abnormality of the labia majora (HP:0012881)1.53946145
186Osteomalacia (HP:0002749)1.52164665

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR5.11519273
2TAOK34.91529179
3BCKDK3.63476801
4CDK123.60913269
5FRK3.52954542
6ERN12.97935837
7SIK12.69706764
8MAP3K22.57436073
9MAPK152.42562876
10FGFR42.31601677
11TNK22.21479903
12EEF2K2.21179267
13BRD42.14428939
14LATS11.88805547
15EIF2AK31.58791326
16PASK1.58208437
17HIPK21.55972395
18IRAK31.54105193
19PTK61.51637073
20PDGFRA1.48598395
21FGFR21.45999536
22TRIB31.43867829
23PRKD31.43437936
24PIK3CG1.39809248
25ICK1.39706372
26EPHA31.37839593
27STK391.37541644
28MAP3K11.29989575
29WNK41.25298985
30NTRK11.23472120
31RIPK11.23321079
32CLK11.22852248
33NLK1.20511360
34YES11.18630122
35PRKCH1.17497456
36FLT31.17407760
37MAP3K31.16701726
38AKT31.15844952
39MAP2K41.14262109
40JAK11.10908511
41NTRK31.10218493
42IRAK11.09397616
43PAK31.09393427
44CDK61.08982945
45BRSK21.07869654
46RET1.05949141
47ERBB41.05082225
48FGFR31.02748423
49MST1R1.00596719
50CAMKK21.00324421
51PTK21.00153920
52CAMK1G0.97947766
53FER0.97717289
54NUAK10.95488505
55JAK20.93078408
56MET0.92308261
57EIF2AK10.92017804
58PKN20.91130438
59ERBB30.90651649
60DAPK20.90381289
61IRAK20.89262151
62NEK60.89174488
63CDC42BPA0.88882754
64BCR0.87249940
65EPHB10.83909846
66SGK30.79284558
67MAP3K40.78559236
68PDGFRB0.78453042
69PNCK0.76571786
70PIK3CA0.76425746
71CASK0.76322490
72PRKAA10.74036492
73CAMK1D0.73608073
74PRKAA20.72535597
75SGK20.70931413
76DYRK1B0.68532553
77WNK10.68302884
78STK30.67456474
79MAP3K70.65868615
80ACVR1B0.64096997
81KSR10.61889060
82CDK90.61675941
83MAPK100.60573318
84SGK4940.60067590
85SGK2230.60067590
86CAMK2D0.58926946
87DDR20.58179813
88ITK0.57351464
89PDPK10.57085393
90TRPM70.56737467
91CAMKK10.56142697
92SGK10.55710486
93CAMK2B0.51583293
94PRKD10.51178866
95PRKACG0.50863061
96PRKCE0.48863571
97SCYL20.48514662
98MAP2K10.48306415
99GSK3A0.48262847
100MTOR0.47619682
101MAPK130.47287015
102CAMK2G0.47088326
103IGF1R0.46645101
104LATS20.46275744
105TAOK10.45918862
106MAPK110.45018929
107UHMK10.43737197
108MAP2K20.43487719
109ATM0.43315102
110CSNK1E0.42563937
111CAMK40.42178388
112PDK10.40936950
113ERBB20.40838147
114CDK30.40316283
115MAP3K130.40228037
116GSK3B0.40101875
117RPS6KA20.39769380
118RAF10.38882866
119MAPK140.38816073
120PRKD20.38809185
121MELK0.38287100
122KSR20.37028998
123MAP3K100.36216536
124NEK90.35873980
125STK380.35642421
126CSK0.35466303
127MAPK10.34014291
128PRKCG0.33735613
129MKNK20.33226894
130DYRK1A0.32978339
131TNIK0.32843428
132CHEK10.32760526
133EIF2AK20.32554716
134TAF10.32484688
135PRKCQ0.31876765
136CAMK2A0.31280135
137RPS6KB10.30370269
138STK38L0.30248637
139CDK70.30055358
140MAPK80.29267681
141MARK20.28973633
142AKT10.28705296
143IRAK40.28554259
144PRKCZ0.28342204
145INSR0.27789369
146TTN0.27699160
147RPS6KA30.27639755

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049504.32939895
2Primary bile acid biosynthesis_Homo sapiens_hsa001203.39025208
3Nitrogen metabolism_Homo sapiens_hsa009102.98208585
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.53162385
5Sulfur metabolism_Homo sapiens_hsa009202.52564334
6Tryptophan metabolism_Homo sapiens_hsa003802.47348886
7Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.41145526
8Arginine biosynthesis_Homo sapiens_hsa002202.35974126
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.19706464
10Complement and coagulation cascades_Homo sapiens_hsa046102.14712245
11Fatty acid degradation_Homo sapiens_hsa000712.06091936
12Butanoate metabolism_Homo sapiens_hsa006501.98012631
13Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.95004933
14Protein export_Homo sapiens_hsa030601.74923732
15Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.73514206
16Histidine metabolism_Homo sapiens_hsa003401.63276667
17Prostate cancer_Homo sapiens_hsa052151.61762175
18Selenocompound metabolism_Homo sapiens_hsa004501.58179040
19Propanoate metabolism_Homo sapiens_hsa006401.57270996
20Pentose and glucuronate interconversions_Homo sapiens_hsa000401.56063925
21Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.53519023
22Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.53479466
23Peroxisome_Homo sapiens_hsa041461.52372385
24PPAR signaling pathway_Homo sapiens_hsa033201.50605960
25Bile secretion_Homo sapiens_hsa049761.49068923
26ABC transporters_Homo sapiens_hsa020101.47435096
27Fatty acid metabolism_Homo sapiens_hsa012121.46890748
28Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.46374954
29Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.44654441
30Fat digestion and absorption_Homo sapiens_hsa049751.40502566
31Starch and sucrose metabolism_Homo sapiens_hsa005001.39379557
32Thyroid cancer_Homo sapiens_hsa052161.31150153
33Endometrial cancer_Homo sapiens_hsa052131.29667079
34Phenylalanine metabolism_Homo sapiens_hsa003601.28041022
35Insulin secretion_Homo sapiens_hsa049111.26768241
36Steroid hormone biosynthesis_Homo sapiens_hsa001401.26011262
37mTOR signaling pathway_Homo sapiens_hsa041501.23333900
38Caffeine metabolism_Homo sapiens_hsa002321.22954349
39beta-Alanine metabolism_Homo sapiens_hsa004101.21598934
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.19944845
41Tyrosine metabolism_Homo sapiens_hsa003501.16158244
42Adherens junction_Homo sapiens_hsa045201.14817238
43FoxO signaling pathway_Homo sapiens_hsa040681.14788117
44Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.12563071
45Staphylococcus aureus infection_Homo sapiens_hsa051501.11541059
46Renin-angiotensin system_Homo sapiens_hsa046141.11361883
47Type II diabetes mellitus_Homo sapiens_hsa049301.10781712
48Chemical carcinogenesis_Homo sapiens_hsa052041.10525514
49Phosphatidylinositol signaling system_Homo sapiens_hsa040701.10504619
50Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.10007968
51Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.08235985
52Drug metabolism - other enzymes_Homo sapiens_hsa009831.02265035
53Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.00782710
54Chronic myeloid leukemia_Homo sapiens_hsa052201.00574959
55Non-small cell lung cancer_Homo sapiens_hsa052230.99779910
56Thyroid hormone signaling pathway_Homo sapiens_hsa049190.96876261
57Pyruvate metabolism_Homo sapiens_hsa006200.95469325
58Fatty acid elongation_Homo sapiens_hsa000620.94810058
59Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.94056264
60Inositol phosphate metabolism_Homo sapiens_hsa005620.93017332
61Lysine degradation_Homo sapiens_hsa003100.91734583
62Retinol metabolism_Homo sapiens_hsa008300.90305593
63Insulin resistance_Homo sapiens_hsa049310.86864383
64Steroid biosynthesis_Homo sapiens_hsa001000.84902521
65Dorso-ventral axis formation_Homo sapiens_hsa043200.84184546
66Mineral absorption_Homo sapiens_hsa049780.81338954
67Renal cell carcinoma_Homo sapiens_hsa052110.79604255
68Carbohydrate digestion and absorption_Homo sapiens_hsa049730.78309575
69Glioma_Homo sapiens_hsa052140.77749651
70Choline metabolism in cancer_Homo sapiens_hsa052310.77586054
71Glycerolipid metabolism_Homo sapiens_hsa005610.76599177
72ErbB signaling pathway_Homo sapiens_hsa040120.76499163
73Prolactin signaling pathway_Homo sapiens_hsa049170.76061310
74Folate biosynthesis_Homo sapiens_hsa007900.74665865
75Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.72348237
76Glucagon signaling pathway_Homo sapiens_hsa049220.72066692
77MicroRNAs in cancer_Homo sapiens_hsa052060.71794983
78Hepatitis C_Homo sapiens_hsa051600.71759139
79Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.68958957
80Arginine and proline metabolism_Homo sapiens_hsa003300.68517030
81Pancreatic secretion_Homo sapiens_hsa049720.68149306
82Prion diseases_Homo sapiens_hsa050200.67719035
83Thyroid hormone synthesis_Homo sapiens_hsa049180.66168347
842-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.65479647
85Pancreatic cancer_Homo sapiens_hsa052120.64984881
86Sphingolipid metabolism_Homo sapiens_hsa006000.64597981
87Acute myeloid leukemia_Homo sapiens_hsa052210.59982909
88AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59402507
89Proteoglycans in cancer_Homo sapiens_hsa052050.57890670
90TGF-beta signaling pathway_Homo sapiens_hsa043500.55015652
91Vitamin digestion and absorption_Homo sapiens_hsa049770.54955713
92Small cell lung cancer_Homo sapiens_hsa052220.52654781
93Amoebiasis_Homo sapiens_hsa051460.52136963
94Jak-STAT signaling pathway_Homo sapiens_hsa046300.50490809
95Renin secretion_Homo sapiens_hsa049240.50094150
96Carbon metabolism_Homo sapiens_hsa012000.47702652
97Other glycan degradation_Homo sapiens_hsa005110.47445614
98Cocaine addiction_Homo sapiens_hsa050300.47156619
99Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.46760784
100Long-term potentiation_Homo sapiens_hsa047200.45661790
101Protein digestion and absorption_Homo sapiens_hsa049740.45265301
102Circadian rhythm_Homo sapiens_hsa047100.43639463
103Adipocytokine signaling pathway_Homo sapiens_hsa049200.43614263
104Lysosome_Homo sapiens_hsa041420.42950337
105Aldosterone synthesis and secretion_Homo sapiens_hsa049250.42919484
106Vibrio cholerae infection_Homo sapiens_hsa051100.41477183
107Transcriptional misregulation in cancer_Homo sapiens_hsa052020.39441139
108Cysteine and methionine metabolism_Homo sapiens_hsa002700.39154168
109N-Glycan biosynthesis_Homo sapiens_hsa005100.38418895
110Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.38191648
111Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.38024601
112HIF-1 signaling pathway_Homo sapiens_hsa040660.37766166
113Focal adhesion_Homo sapiens_hsa045100.37683141
114Biosynthesis of amino acids_Homo sapiens_hsa012300.37671168
115Glycosaminoglycan degradation_Homo sapiens_hsa005310.36980983
116AMPK signaling pathway_Homo sapiens_hsa041520.36876684
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.36404569
118Fatty acid biosynthesis_Homo sapiens_hsa000610.35959131
119Colorectal cancer_Homo sapiens_hsa052100.35551376
120Type I diabetes mellitus_Homo sapiens_hsa049400.35322060
121Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.32866019
122Galactose metabolism_Homo sapiens_hsa000520.32462833
123Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.32324160
124alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.31634366
125Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.31599438
126Insulin signaling pathway_Homo sapiens_hsa049100.31385033
127Taste transduction_Homo sapiens_hsa047420.29839921
128Amphetamine addiction_Homo sapiens_hsa050310.29497092
129Ovarian steroidogenesis_Homo sapiens_hsa049130.26185460
130GABAergic synapse_Homo sapiens_hsa047270.26140671
131Linoleic acid metabolism_Homo sapiens_hsa005910.25762092
132Longevity regulating pathway - mammal_Homo sapiens_hsa042110.24632599
133Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.24233756
134Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.24001177
135Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.23725314
136Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.22712258
137Metabolic pathways_Homo sapiens_hsa011000.22045579
138Glycerophospholipid metabolism_Homo sapiens_hsa005640.20546205
139Estrogen signaling pathway_Homo sapiens_hsa049150.19796238
140Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.18582573

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