

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | germinal center formation (GO:0002467) | 7.32811160 |
| 2 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.92703422 |
| 3 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 6.90367687 |
| 4 | regulation of memory T cell differentiation (GO:0043380) | 6.59500872 |
| 5 | antigen processing and presentation of endogenous antigen (GO:0019883) | 6.26780665 |
| 6 | negative regulation of T-helper cell differentiation (GO:0045623) | 6.22792071 |
| 7 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 6.22792071 |
| 8 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 5.65005387 |
| 9 | regulation of T-helper 2 cell differentiation (GO:0045628) | 5.63318359 |
| 10 | negative regulation of B cell apoptotic process (GO:0002903) | 5.43105213 |
| 11 | negative regulation of type 2 immune response (GO:0002829) | 5.34349210 |
| 12 | regulation of germinal center formation (GO:0002634) | 5.19728375 |
| 13 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.11739832 |
| 14 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 5.11476266 |
| 15 | negative regulation of B cell mediated immunity (GO:0002713) | 5.11476266 |
| 16 | growth hormone receptor signaling pathway (GO:0060396) | 4.83620543 |
| 17 | innate immune response in mucosa (GO:0002227) | 4.74757875 |
| 18 | phagocytosis, recognition (GO:0006910) | 4.70368868 |
| 19 | negative regulation of Rho protein signal transduction (GO:0035024) | 4.67135478 |
| 20 | negative regulation of viral entry into host cell (GO:0046597) | 4.65248967 |
| 21 | negative regulation of cell killing (GO:0031342) | 4.58191036 |
| 22 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.58191036 |
| 23 | fatty acid elongation (GO:0030497) | 4.56362573 |
| 24 | NIK/NF-kappaB signaling (GO:0038061) | 4.42639802 |
| 25 | regulation of hypersensitivity (GO:0002883) | 4.40510657 |
| 26 | mucosal immune response (GO:0002385) | 4.30088583 |
| 27 | regulation of viral entry into host cell (GO:0046596) | 4.27526498 |
| 28 | cellular response to growth hormone stimulus (GO:0071378) | 4.23934222 |
| 29 | antigen processing and presentation via MHC class Ib (GO:0002475) | 4.21827318 |
| 30 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.21509089 |
| 31 | organ or tissue specific immune response (GO:0002251) | 4.18670481 |
| 32 | positive regulation by symbiont of host defense response (GO:0052509) | 4.18261166 |
| 33 | modulation by symbiont of host defense response (GO:0052031) | 4.18261166 |
| 34 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.18261166 |
| 35 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.18261166 |
| 36 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.18261166 |
| 37 | modulation by symbiont of host immune response (GO:0052553) | 4.18261166 |
| 38 | regulation of B cell apoptotic process (GO:0002902) | 4.12165649 |
| 39 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 4.12011377 |
| 40 | immunoglobulin mediated immune response (GO:0016064) | 4.09756565 |
| 41 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 4.08229063 |
| 42 | neutrophil activation involved in immune response (GO:0002283) | 4.05809325 |
| 43 | positive regulation of antigen processing and presentation (GO:0002579) | 3.94395373 |
| 44 | detection of other organism (GO:0098543) | 3.88461084 |
| 45 | response to peptidoglycan (GO:0032494) | 3.84051566 |
| 46 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.76918776 |
| 47 | detection of bacterium (GO:0016045) | 3.76454549 |
| 48 | myeloid leukocyte mediated immunity (GO:0002444) | 3.76065198 |
| 49 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.72278071 |
| 50 | positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) | 3.65855483 |
| 51 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.56329200 |
| 52 | regulation of antigen processing and presentation (GO:0002577) | 3.55063425 |
| 53 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.54716630 |
| 54 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.53688818 |
| 55 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.53460977 |
| 56 | necrotic cell death (GO:0070265) | 3.53447327 |
| 57 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.50808835 |
| 58 | neutrophil activation (GO:0042119) | 3.50475275 |
| 59 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.47554682 |
| 60 | antibacterial humoral response (GO:0019731) | 3.46033256 |
| 61 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.45666373 |
| 62 | detection of external biotic stimulus (GO:0098581) | 3.41943300 |
| 63 | detection of molecule of bacterial origin (GO:0032490) | 3.40501244 |
| 64 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.40167933 |
| 65 | negative regulation of alpha-beta T cell activation (GO:0046636) | 3.38066428 |
| 66 | type I interferon signaling pathway (GO:0060337) | 3.37485820 |
| 67 | cellular response to type I interferon (GO:0071357) | 3.37485820 |
| 68 | response to type I interferon (GO:0034340) | 3.35901981 |
| 69 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.35750047 |
| 70 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.33617084 |
| 71 | B cell mediated immunity (GO:0019724) | 3.31661500 |
| 72 | antimicrobial humoral response (GO:0019730) | 3.30889819 |
| 73 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.29411865 |
| 74 | regulation of T-helper cell differentiation (GO:0045622) | 3.28089161 |
| 75 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 3.23296371 |
| 76 | positive regulation of T cell mediated immunity (GO:0002711) | 3.21372878 |
| 77 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.16953311 |
| 78 | regulation of mast cell degranulation (GO:0043304) | 3.13450253 |
| 79 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.10745552 |
| 80 | macrophage activation involved in immune response (GO:0002281) | 3.10413029 |
| 81 | negative regulation of interleukin-12 production (GO:0032695) | 3.10287531 |
| 82 | regulation of type 2 immune response (GO:0002828) | 3.07727569 |
| 83 | programmed necrotic cell death (GO:0097300) | 3.07224302 |
| 84 | defense response to Gram-positive bacterium (GO:0050830) | 3.06897008 |
| 85 | regulation of B cell mediated immunity (GO:0002712) | 3.06690678 |
| 86 | granulocyte activation (GO:0036230) | 3.05870840 |
| 87 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.05107575 |
| 88 | regulation of viral release from host cell (GO:1902186) | 2.98702750 |
| 89 | positive regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.98135005 |
| 90 | negative regulation of defense response to virus (GO:0050687) | 2.97040537 |
| 91 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.95771343 |
| 92 | regulation of isotype switching (GO:0045191) | 2.94977856 |
| 93 | regulation of T cell mediated immunity (GO:0002709) | 2.94904491 |
| 94 | phagocytosis, engulfment (GO:0006911) | 2.94319475 |
| 95 | poly(A)+ mRNA export from nucleus (GO:0016973) | 2.93378727 |
| 96 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.91729635 |
| 97 | positive regulation of adaptive immune response (GO:0002821) | 2.89029710 |
| 98 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.88833948 |
| 99 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli | 2.88309751 |
| 100 | regulation of adaptive immune response based on somatic recombination of immune receptors built from | 2.87798273 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.85620412 |
| 2 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.56235228 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.48019023 |
| 4 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.00284377 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.95698078 |
| 6 | SPI1_23127762_ChIP-Seq_K562_Human | 2.85565853 |
| 7 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 2.81552176 |
| 8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.70515878 |
| 9 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.53159432 |
| 10 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.51859960 |
| 11 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.50270424 |
| 12 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.50199955 |
| 13 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.49392363 |
| 14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.48802014 |
| 15 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.44714695 |
| 16 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.44150875 |
| 17 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.42953089 |
| 18 | MAF_26560356_Chip-Seq_TH1_Human | 2.41822942 |
| 19 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.40476828 |
| 20 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.38104992 |
| 21 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.33228694 |
| 22 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 2.29437552 |
| 23 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.25406261 |
| 24 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.20563684 |
| 25 | GATA1_19941826_ChIP-Seq_K562_Human | 2.13036950 |
| 26 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.01432001 |
| 27 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.00478811 |
| 28 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.91686899 |
| 29 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.79789904 |
| 30 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.79164284 |
| 31 | UTX_26944678_Chip-Seq_JUKART_Human | 1.78778461 |
| 32 | MYB_26560356_Chip-Seq_TH2_Human | 1.77392841 |
| 33 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.73127101 |
| 34 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.69474388 |
| 35 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.68956024 |
| 36 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.68831481 |
| 37 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.67072835 |
| 38 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.60578186 |
| 39 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.59393606 |
| 40 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.58738289 |
| 41 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.58222698 |
| 42 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.58089765 |
| 43 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57280527 |
| 44 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 1.56023408 |
| 45 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.55932366 |
| 46 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.55867204 |
| 47 | MYC_22102868_ChIP-Seq_BL_Human | 1.55859851 |
| 48 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.53342904 |
| 49 | MAF_26560356_Chip-Seq_TH2_Human | 1.53150534 |
| 50 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.51414104 |
| 51 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.48768621 |
| 52 | P68_20966046_ChIP-Seq_HELA_Human | 1.46115904 |
| 53 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.44917113 |
| 54 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.44024342 |
| 55 | MYB_26560356_Chip-Seq_TH1_Human | 1.43534920 |
| 56 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.41650645 |
| 57 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.40964152 |
| 58 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.40222700 |
| 59 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.38556189 |
| 60 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.37854251 |
| 61 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.36548460 |
| 62 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.34993356 |
| 63 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.34513371 |
| 64 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.30685197 |
| 65 | GATA3_26560356_Chip-Seq_TH2_Human | 1.28833632 |
| 66 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 1.28207395 |
| 67 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.26524788 |
| 68 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.23787732 |
| 69 | GATA2_19941826_ChIP-Seq_K562_Human | 1.23601667 |
| 70 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.22951186 |
| 71 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.22771843 |
| 72 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.22216146 |
| 73 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.19255607 |
| 74 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.18175267 |
| 75 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.16221985 |
| 76 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.15909110 |
| 77 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.13941803 |
| 78 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.12993531 |
| 79 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.10304143 |
| 80 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.09392672 |
| 81 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.09320178 |
| 82 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.08971953 |
| 83 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.07602853 |
| 84 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06738911 |
| 85 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.05225467 |
| 86 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.04363390 |
| 87 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.04171844 |
| 88 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.03486002 |
| 89 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02667804 |
| 90 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.01915331 |
| 91 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.00624210 |
| 92 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.99885650 |
| 93 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.99513848 |
| 94 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 0.97119484 |
| 95 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.96932215 |
| 96 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.96031784 |
| 97 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.95123949 |
| 98 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.94047822 |
| 99 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.93108235 |
| 100 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.90055697 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002138_abnormal_hepatobiliary_system | 6.04319890 |
| 2 | MP0004381_abnormal_hair_follicle | 4.49227396 |
| 3 | MP0001835_abnormal_antigen_presentation | 4.20752014 |
| 4 | MP0003724_increased_susceptibility_to | 3.88191328 |
| 5 | MP0000685_abnormal_immune_system | 3.04506587 |
| 6 | MP0005075_abnormal_melanosome_morpholog | 3.03519136 |
| 7 | MP0008057_abnormal_DNA_replication | 2.92199727 |
| 8 | MP0002166_altered_tumor_susceptibility | 2.68076063 |
| 9 | MP0004858_abnormal_nervous_system | 2.63247574 |
| 10 | MP0003436_decreased_susceptibility_to | 2.59226168 |
| 11 | MP0009785_altered_susceptibility_to | 2.51268785 |
| 12 | MP0005167_abnormal_blood-brain_barrier | 2.45978729 |
| 13 | MP0001790_abnormal_immune_system | 2.23055083 |
| 14 | MP0005387_immune_system_phenotype | 2.23055083 |
| 15 | MP0003300_gastrointestinal_ulcer | 2.20171384 |
| 16 | MP0001800_abnormal_humoral_immune | 2.11959430 |
| 17 | MP0005025_abnormal_response_to | 2.07237438 |
| 18 | MP0002419_abnormal_innate_immunity | 2.04478525 |
| 19 | MP0002006_tumorigenesis | 2.02924859 |
| 20 | MP0001853_heart_inflammation | 1.97640434 |
| 21 | MP0004947_skin_inflammation | 1.88365579 |
| 22 | MP0002723_abnormal_immune_serum | 1.88243255 |
| 23 | MP0002405_respiratory_system_inflammati | 1.87761641 |
| 24 | MP0005000_abnormal_immune_tolerance | 1.84377981 |
| 25 | MP0003303_peritoneal_inflammation | 1.80226587 |
| 26 | MP0002254_reproductive_system_inflammat | 1.80027482 |
| 27 | MP0002420_abnormal_adaptive_immunity | 1.77072392 |
| 28 | MP0002452_abnormal_antigen_presenting | 1.76919094 |
| 29 | MP0001819_abnormal_immune_cell | 1.74478702 |
| 30 | MP0002277_abnormal_respiratory_mucosa | 1.71163286 |
| 31 | MP0002132_abnormal_respiratory_system | 1.68417235 |
| 32 | MP0005464_abnormal_platelet_physiology | 1.63023099 |
| 33 | MP0002398_abnormal_bone_marrow | 1.59110188 |
| 34 | MP0003172_abnormal_lysosome_physiology | 1.59025390 |
| 35 | MP0005310_abnormal_salivary_gland | 1.58738595 |
| 36 | MP0004510_myositis | 1.57099514 |
| 37 | MP0006082_CNS_inflammation | 1.51447671 |
| 38 | MP0003879_abnormal_hair_cell | 1.48853402 |
| 39 | MP0000716_abnormal_immune_system | 1.47307022 |
| 40 | MP0000465_gastrointestinal_hemorrhage | 1.46973269 |
| 41 | MP0002396_abnormal_hematopoietic_system | 1.46183434 |
| 42 | MP0003866_abnormal_defecation | 1.46111720 |
| 43 | MP0004147_increased_porphyrin_level | 1.45080936 |
| 44 | MP0002148_abnormal_hypersensitivity_rea | 1.44932549 |
| 45 | MP0001542_abnormal_bone_strength | 1.41107097 |
| 46 | MP0008875_abnormal_xenobiotic_pharmacok | 1.38503302 |
| 47 | MP0010155_abnormal_intestine_physiology | 1.36603600 |
| 48 | MP0002722_abnormal_immune_system | 1.33232077 |
| 49 | MP0001845_abnormal_inflammatory_respons | 1.32111940 |
| 50 | MP0000703_abnormal_thymus_morphology | 1.31689386 |
| 51 | MP0003763_abnormal_thymus_physiology | 1.31530251 |
| 52 | MP0003195_calcinosis | 1.28584165 |
| 53 | MP0005360_urolithiasis | 1.27506841 |
| 54 | MP0005535_abnormal_body_temperature | 1.27203389 |
| 55 | MP0000689_abnormal_spleen_morphology | 1.25219829 |
| 56 | MP0005671_abnormal_response_to | 1.24998866 |
| 57 | MP0009333_abnormal_splenocyte_physiolog | 1.21923307 |
| 58 | MP0002429_abnormal_blood_cell | 1.21183393 |
| 59 | MP0001545_abnormal_hematopoietic_system | 1.19684957 |
| 60 | MP0005397_hematopoietic_system_phenotyp | 1.19684957 |
| 61 | MP0001533_abnormal_skeleton_physiology | 1.14771382 |
| 62 | MP0003191_abnormal_cellular_cholesterol | 1.14391153 |
| 63 | MP0004130_abnormal_muscle_cell | 1.11933484 |
| 64 | MP0003828_pulmonary_edema | 1.10896988 |
| 65 | MP0001873_stomach_inflammation | 1.10630164 |
| 66 | MP0003646_muscle_fatigue | 1.08141007 |
| 67 | MP0001851_eye_inflammation | 1.08009697 |
| 68 | MP0004043_abnormal_pH_regulation | 1.06655127 |
| 69 | MP0010234_abnormal_vibrissa_follicle | 0.99379280 |
| 70 | MP0009764_decreased_sensitivity_to | 0.97909292 |
| 71 | MP0002638_abnormal_pupillary_reflex | 0.97753938 |
| 72 | MP0008004_abnormal_stomach_pH | 0.97416623 |
| 73 | MP0006054_spinal_hemorrhage | 0.96611824 |
| 74 | MP0008469_abnormal_protein_level | 0.94109981 |
| 75 | MP0004808_abnormal_hematopoietic_stem | 0.85094950 |
| 76 | MP0001849_ear_inflammation | 0.83317397 |
| 77 | MP0008961_abnormal_basal_metabolism | 0.82807130 |
| 78 | MP0009278_abnormal_bone_marrow | 0.82061468 |
| 79 | MP0003091_abnormal_cell_migration | 0.80923239 |
| 80 | MP0002998_abnormal_bone_remodeling | 0.80003297 |
| 81 | MP0003221_abnormal_cardiomyocyte_apopto | 0.79076433 |
| 82 | MP0002653_abnormal_ependyma_morphology | 0.77380993 |
| 83 | MP0000609_abnormal_liver_physiology | 0.69572298 |
| 84 | MP0002971_abnormal_brown_adipose | 0.67940064 |
| 85 | MP0003795_abnormal_bone_structure | 0.63036389 |
| 86 | MP0000858_altered_metastatic_potential | 0.62567511 |
| 87 | MP0003690_abnormal_glial_cell | 0.61251392 |
| 88 | MP0002089_abnormal_postnatal_growth/wei | 0.59000166 |
| 89 | MP0005164_abnormal_response_to | 0.58192925 |
| 90 | MP0009763_increased_sensitivity_to | 0.57930651 |
| 91 | MP0001986_abnormal_taste_sensitivity | 0.57319968 |
| 92 | MP0000613_abnormal_salivary_gland | 0.57254118 |
| 93 | MP0000313_abnormal_cell_death | 0.55496368 |
| 94 | MP0002796_impaired_skin_barrier | 0.54173227 |
| 95 | MP0004883_abnormal_blood_vessel | 0.53927543 |
| 96 | MP0003075_altered_response_to | 0.53905358 |
| 97 | MP0003453_abnormal_keratinocyte_physiol | 0.53502178 |
| 98 | MP0005377_hearing/vestibular/ear_phenot | 0.53251968 |
| 99 | MP0003878_abnormal_ear_physiology | 0.53251968 |
| 100 | MP0003183_abnormal_peptide_metabolism | 0.53053576 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 9.85778512 |
| 2 | Abnormality of the fingertips (HP:0001211) | 6.10627087 |
| 3 | Large eyes (HP:0001090) | 5.85120274 |
| 4 | Chronic otitis media (HP:0000389) | 5.66862009 |
| 5 | Orchitis (HP:0100796) | 4.54585773 |
| 6 | Retrobulbar optic neuritis (HP:0100654) | 4.53880877 |
| 7 | Optic neuritis (HP:0100653) | 4.53880877 |
| 8 | Myositis (HP:0100614) | 4.48326936 |
| 9 | Mediastinal lymphadenopathy (HP:0100721) | 4.37401078 |
| 10 | Eczematoid dermatitis (HP:0000976) | 4.37078478 |
| 11 | Abnormality of the peritoneum (HP:0002585) | 4.27210760 |
| 12 | Nasal polyposis (HP:0100582) | 4.21084543 |
| 13 | Reduced subcutaneous adipose tissue (HP:0003758) | 3.95781928 |
| 14 | Gastrointestinal infarctions (HP:0005244) | 3.88752268 |
| 15 | Chronic sinusitis (HP:0011109) | 3.76737287 |
| 16 | Prolonged bleeding time (HP:0003010) | 3.65839597 |
| 17 | Microcytic anemia (HP:0001935) | 3.63383150 |
| 18 | Meningitis (HP:0001287) | 3.45016821 |
| 19 | Increased IgE level (HP:0003212) | 3.44333894 |
| 20 | Recurrent bacterial skin infections (HP:0005406) | 3.42756146 |
| 21 | Encephalitis (HP:0002383) | 3.39716027 |
| 22 | Recurrent abscess formation (HP:0002722) | 3.35773531 |
| 23 | Hypergammaglobulinemia (HP:0010702) | 3.35421244 |
| 24 | Abnormality of the nasal mucosa (HP:0000433) | 3.33443826 |
| 25 | Basal ganglia calcification (HP:0002135) | 3.27557968 |
| 26 | Abnormality of macrophages (HP:0004311) | 3.12912135 |
| 27 | Keratoconjunctivitis sicca (HP:0001097) | 3.09029329 |
| 28 | Recurrent fungal infections (HP:0002841) | 3.04352472 |
| 29 | Abnormality of the pleura (HP:0002103) | 2.92067118 |
| 30 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.91326181 |
| 31 | Keratoconjunctivitis (HP:0001096) | 2.88860886 |
| 32 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.86146053 |
| 33 | Chest pain (HP:0100749) | 2.79666537 |
| 34 | Hypochromic microcytic anemia (HP:0004840) | 2.79196765 |
| 35 | Recurrent bronchitis (HP:0002837) | 2.76841718 |
| 36 | Peritonitis (HP:0002586) | 2.76413736 |
| 37 | Hypertriglyceridemia (HP:0002155) | 2.72232615 |
| 38 | Epistaxis (HP:0000421) | 2.71551561 |
| 39 | Hypochromic anemia (HP:0001931) | 2.69850917 |
| 40 | 3-Methylglutaconic aciduria (HP:0003535) | 2.68129775 |
| 41 | Spontaneous hematomas (HP:0007420) | 2.64857838 |
| 42 | Vasculitis (HP:0002633) | 2.63379233 |
| 43 | Chronic obstructive pulmonary disease (HP:0006510) | 2.61368065 |
| 44 | Obstructive lung disease (HP:0006536) | 2.61368065 |
| 45 | Arterial thrombosis (HP:0004420) | 2.59833679 |
| 46 | Gingival bleeding (HP:0000225) | 2.58404719 |
| 47 | Abnormality of alanine metabolism (HP:0010916) | 2.57481858 |
| 48 | Hyperalaninemia (HP:0003348) | 2.57481858 |
| 49 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.57481858 |
| 50 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.57221943 |
| 51 | Petechiae (HP:0000967) | 2.50492047 |
| 52 | Arthropathy (HP:0003040) | 2.45767158 |
| 53 | Stomatitis (HP:0010280) | 2.45010508 |
| 54 | Anorexia (HP:0002039) | 2.44895955 |
| 55 | Skin rash (HP:0000988) | 2.40369694 |
| 56 | Flat occiput (HP:0005469) | 2.38235752 |
| 57 | Leukocytosis (HP:0001974) | 2.35250616 |
| 58 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.34908512 |
| 59 | Recurrent cutaneous fungal infections (HP:0011370) | 2.34908512 |
| 60 | Recurrent skin infections (HP:0001581) | 2.34647087 |
| 61 | Macroglossia (HP:0000158) | 2.33277122 |
| 62 | Granulocytopenia (HP:0001913) | 2.31927466 |
| 63 | Clubbing of toes (HP:0100760) | 2.29322258 |
| 64 | Autoimmune thrombocytopenia (HP:0001973) | 2.27031385 |
| 65 | Ileus (HP:0002595) | 2.25824637 |
| 66 | Hemoptysis (HP:0002105) | 2.22623620 |
| 67 | Eosinophilia (HP:0001880) | 2.22482785 |
| 68 | Abnormality of the endocardium (HP:0004306) | 2.21349072 |
| 69 | Urticaria (HP:0001025) | 2.21275710 |
| 70 | Menorrhagia (HP:0000132) | 2.19094842 |
| 71 | Erythema (HP:0010783) | 2.18050806 |
| 72 | Prominent nose (HP:0000448) | 2.17675400 |
| 73 | Inflammation of the large intestine (HP:0002037) | 2.12865456 |
| 74 | Emphysema (HP:0002097) | 2.10873257 |
| 75 | Pulmonary infiltrates (HP:0002113) | 2.10775081 |
| 76 | Cellulitis (HP:0100658) | 2.10101209 |
| 77 | Pulmonary embolism (HP:0002204) | 2.08288961 |
| 78 | Abnormal platelet volume (HP:0011876) | 2.05581531 |
| 79 | Abnormality of iron homeostasis (HP:0011031) | 2.01975081 |
| 80 | Polycythemia (HP:0001901) | 2.01946326 |
| 81 | Increased serum ferritin (HP:0003281) | 2.01460382 |
| 82 | Episodic fever (HP:0001954) | 1.99614071 |
| 83 | Sepsis (HP:0100806) | 1.98311513 |
| 84 | Cerebellar dysplasia (HP:0007033) | 1.97329188 |
| 85 | Gastrointestinal inflammation (HP:0004386) | 1.92892881 |
| 86 | Lymphedema (HP:0001004) | 1.92334842 |
| 87 | Cardiomegaly (HP:0001640) | 1.91698855 |
| 88 | Acute lymphatic leukemia (HP:0006721) | 1.89449746 |
| 89 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.88881268 |
| 90 | Delayed CNS myelination (HP:0002188) | 1.87518814 |
| 91 | Amyloidosis (HP:0011034) | 1.85561499 |
| 92 | Gingivitis (HP:0000230) | 1.84631177 |
| 93 | Increased IgM level (HP:0003496) | 1.84429959 |
| 94 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.81929299 |
| 95 | Bronchitis (HP:0012387) | 1.81013882 |
| 96 | Gangrene (HP:0100758) | 1.80945947 |
| 97 | Purpura (HP:0000979) | 1.80726703 |
| 98 | Testicular atrophy (HP:0000029) | 1.80537063 |
| 99 | Recurrent pneumonia (HP:0006532) | 1.75227131 |
| 100 | Abnormality of the basal ganglia (HP:0002134) | 1.74502191 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 3.74848342 |
| 2 | SIK2 | 3.46932325 |
| 3 | IRAK1 | 2.85360200 |
| 4 | BLK | 2.50553945 |
| 5 | MAP4K1 | 2.36908535 |
| 6 | MAP3K14 | 2.33876929 |
| 7 | SIK3 | 2.31530364 |
| 8 | MARK3 | 2.24016645 |
| 9 | MAP3K13 | 2.21851302 |
| 10 | MAP3K2 | 2.19376545 |
| 11 | KSR2 | 2.15031841 |
| 12 | IRAK2 | 2.08368442 |
| 13 | TAOK1 | 1.94610632 |
| 14 | IRAK4 | 1.93179576 |
| 15 | CHUK | 1.91671578 |
| 16 | EPHB1 | 1.88154740 |
| 17 | MAP3K5 | 1.87964986 |
| 18 | IKBKB | 1.85525768 |
| 19 | TYK2 | 1.81749554 |
| 20 | ERN1 | 1.78622295 |
| 21 | MAP2K3 | 1.78213960 |
| 22 | ACVR1B | 1.74907098 |
| 23 | IKBKE | 1.73357528 |
| 24 | EPHA3 | 1.73010161 |
| 25 | KSR1 | 1.71874171 |
| 26 | AKT3 | 1.70033022 |
| 27 | DYRK3 | 1.51762299 |
| 28 | SIK1 | 1.47943815 |
| 29 | DYRK1B | 1.47024861 |
| 30 | CDK12 | 1.45318821 |
| 31 | MAP3K11 | 1.38599014 |
| 32 | FRK | 1.38493838 |
| 33 | JAK3 | 1.37654790 |
| 34 | TBK1 | 1.34699167 |
| 35 | TLK1 | 1.34572414 |
| 36 | CSK | 1.33891677 |
| 37 | GRK6 | 1.25942748 |
| 38 | TXK | 1.23516711 |
| 39 | JAK2 | 1.21125596 |
| 40 | TNK2 | 1.18719742 |
| 41 | MAP3K1 | 1.14209675 |
| 42 | HCK | 1.13282204 |
| 43 | NLK | 1.13201398 |
| 44 | SYK | 1.05797570 |
| 45 | MAP3K3 | 1.02663115 |
| 46 | PTK6 | 1.00130206 |
| 47 | MARK2 | 0.95434528 |
| 48 | ZAP70 | 0.94418324 |
| 49 | FGR | 0.92735257 |
| 50 | STK11 | 0.92517475 |
| 51 | FER | 0.92236632 |
| 52 | WNK4 | 0.92233380 |
| 53 | RAF1 | 0.92179582 |
| 54 | JAK1 | 0.91828751 |
| 55 | ARAF | 0.91018527 |
| 56 | BTK | 0.89223742 |
| 57 | DAPK2 | 0.85322066 |
| 58 | PDK1 | 0.85188551 |
| 59 | YES1 | 0.83822899 |
| 60 | PDPK1 | 0.82889073 |
| 61 | BRAF | 0.80846367 |
| 62 | TAOK3 | 0.80744522 |
| 63 | PIM1 | 0.77046973 |
| 64 | KIT | 0.77014704 |
| 65 | TAOK2 | 0.76287846 |
| 66 | WNK1 | 0.75317463 |
| 67 | PIK3CG | 0.75087997 |
| 68 | BMPR2 | 0.73127554 |
| 69 | LYN | 0.72189838 |
| 70 | RPS6KA5 | 0.67467156 |
| 71 | FES | 0.67231633 |
| 72 | PRKAA1 | 0.61751595 |
| 73 | ABL2 | 0.61280468 |
| 74 | RPS6KA1 | 0.61032922 |
| 75 | PKN1 | 0.59158774 |
| 76 | FGFR3 | 0.57360851 |
| 77 | MATK | 0.55994944 |
| 78 | DYRK1A | 0.54624845 |
| 79 | FGFR4 | 0.54423982 |
| 80 | TEC | 0.53622390 |
| 81 | SGK3 | 0.51968042 |
| 82 | MAPK11 | 0.51241568 |
| 83 | ZAK | 0.51147551 |
| 84 | CAMK1D | 0.51058803 |
| 85 | MAP3K8 | 0.50372132 |
| 86 | MAP3K9 | 0.49740100 |
| 87 | BRD4 | 0.48776193 |
| 88 | CDK9 | 0.46268580 |
| 89 | BMX | 0.45653323 |
| 90 | MAP3K7 | 0.45349191 |
| 91 | PAK1 | 0.44814131 |
| 92 | MAP2K1 | 0.43814735 |
| 93 | PRKCZ | 0.43276195 |
| 94 | MAPK12 | 0.42255558 |
| 95 | SGK2 | 0.41195076 |
| 96 | LCK | 0.40419104 |
| 97 | CSF1R | 0.37379843 |
| 98 | ADRBK2 | 0.35713542 |
| 99 | STK4 | 0.35663402 |
| 100 | CAMK1 | 0.34015041 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 5.06369287 |
| 2 | Alcoholism_Homo sapiens_hsa05034 | 3.36252998 |
| 3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.99312437 |
| 4 | Viral carcinogenesis_Homo sapiens_hsa05203 | 2.90424147 |
| 5 | Leishmaniasis_Homo sapiens_hsa05140 | 2.53344540 |
| 6 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.48644640 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.33759219 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.33364490 |
| 9 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.24385511 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.05806107 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.97792208 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.86086620 |
| 13 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.80455251 |
| 14 | Tuberculosis_Homo sapiens_hsa05152 | 1.77739508 |
| 15 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.73033231 |
| 16 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.69907885 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.69516415 |
| 18 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.63394338 |
| 19 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.61993453 |
| 20 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.61218961 |
| 21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.56674010 |
| 22 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.55718609 |
| 23 | Malaria_Homo sapiens_hsa05144 | 1.53401403 |
| 24 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.50268127 |
| 25 | Legionellosis_Homo sapiens_hsa05134 | 1.45707618 |
| 26 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.44134332 |
| 27 | Measles_Homo sapiens_hsa05162 | 1.43910687 |
| 28 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.43216774 |
| 29 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.40286028 |
| 30 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.32861104 |
| 31 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.31545554 |
| 32 | Influenza A_Homo sapiens_hsa05164 | 1.27680442 |
| 33 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.21629273 |
| 34 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.16789583 |
| 35 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.15234292 |
| 36 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.14792668 |
| 37 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.14306722 |
| 38 | Phagosome_Homo sapiens_hsa04145 | 1.14151541 |
| 39 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.12250540 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 1.11987635 |
| 41 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.10317205 |
| 42 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.09138346 |
| 43 | Hepatitis C_Homo sapiens_hsa05160 | 1.09061932 |
| 44 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.03839692 |
| 45 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.01516147 |
| 46 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.99212917 |
| 47 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.96385215 |
| 48 | Platelet activation_Homo sapiens_hsa04611 | 0.94688833 |
| 49 | ABC transporters_Homo sapiens_hsa02010 | 0.91979437 |
| 50 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.91662166 |
| 51 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.81644874 |
| 52 | Shigellosis_Homo sapiens_hsa05131 | 0.78610764 |
| 53 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.78554895 |
| 54 | Hepatitis B_Homo sapiens_hsa05161 | 0.76615686 |
| 55 | Apoptosis_Homo sapiens_hsa04210 | 0.76252221 |
| 56 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.75534835 |
| 57 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.74401320 |
| 58 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.68966880 |
| 59 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.68727770 |
| 60 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.68195126 |
| 61 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.68153140 |
| 62 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.67753078 |
| 63 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.65955130 |
| 64 | Circadian rhythm_Homo sapiens_hsa04710 | 0.65906164 |
| 65 | Asthma_Homo sapiens_hsa05310 | 0.65207956 |
| 66 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.59030526 |
| 67 | Endometrial cancer_Homo sapiens_hsa05213 | 0.58337292 |
| 68 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.58049598 |
| 69 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.57084107 |
| 70 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.56609799 |
| 71 | Salmonella infection_Homo sapiens_hsa05132 | 0.54952127 |
| 72 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.53709280 |
| 73 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.50740338 |
| 74 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.48379282 |
| 75 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.47207050 |
| 76 | Endocytosis_Homo sapiens_hsa04144 | 0.45618685 |
| 77 | Bladder cancer_Homo sapiens_hsa05219 | 0.43488081 |
| 78 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.42374481 |
| 79 | Thyroid cancer_Homo sapiens_hsa05216 | 0.41374554 |
| 80 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.41350036 |
| 81 | Olfactory transduction_Homo sapiens_hsa04740 | 0.37845999 |
| 82 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.36086702 |
| 83 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.33169313 |
| 84 | Pertussis_Homo sapiens_hsa05133 | 0.32613796 |
| 85 | Insulin resistance_Homo sapiens_hsa04931 | 0.32349147 |
| 86 | HTLV-I infection_Homo sapiens_hsa05166 | 0.31788340 |
| 87 | Prostate cancer_Homo sapiens_hsa05215 | 0.31627524 |
| 88 | Taste transduction_Homo sapiens_hsa04742 | 0.30220841 |
| 89 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.29923026 |
| 90 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.28686939 |
| 91 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.28350230 |
| 92 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.27856094 |
| 93 | Colorectal cancer_Homo sapiens_hsa05210 | 0.27483881 |
| 94 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.26821331 |
| 95 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.26764968 |
| 96 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.26608273 |
| 97 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.26011860 |
| 98 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.25090690 |
| 99 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.23485463 |
| 100 | Long-term depression_Homo sapiens_hsa04730 | 0.20268406 |

