MIDN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell-cell junction maintenance (GO:0045217)4.34379224
2planar cell polarity pathway involved in neural tube closure (GO:0090179)4.07229045
3regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.96530261
4negative regulation of erythrocyte differentiation (GO:0045647)3.88992339
5hippo signaling (GO:0035329)3.80239988
6paraxial mesoderm development (GO:0048339)3.71142062
7polarized epithelial cell differentiation (GO:0030859)3.57856534
8regulation of hippo signaling (GO:0035330)3.55268480
9modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.53314169
10positive regulation by organism of defense response of other organism involved in symbiotic interact3.53314169
11modulation by symbiont of host immune response (GO:0052553)3.53314169
12positive regulation by symbiont of host defense response (GO:0052509)3.53314169
13modulation by symbiont of host defense response (GO:0052031)3.53314169
14modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.53314169
15pre-miRNA processing (GO:0031054)3.39819173
16cell junction maintenance (GO:0034331)3.30697358
17intracellular estrogen receptor signaling pathway (GO:0030520)3.30663576
18response to laminar fluid shear stress (GO:0034616)3.21403763
19apoptotic process involved in morphogenesis (GO:0060561)3.16129493
20response to peptidoglycan (GO:0032494)3.15843340
21cell migration in hindbrain (GO:0021535)3.14949302
223-UTR-mediated mRNA stabilization (GO:0070935)3.14737702
23response to muramyl dipeptide (GO:0032495)3.09047696
24positive regulation of histone deacetylation (GO:0031065)3.08128213
25mRNA stabilization (GO:0048255)3.06863341
26RNA stabilization (GO:0043489)3.06863341
27negative regulation of catenin import into nucleus (GO:0035414)3.05421614
28embryonic foregut morphogenesis (GO:0048617)3.04523086
29heterochromatin organization (GO:0070828)3.03850026
30adherens junction assembly (GO:0034333)3.03014099
31gastrulation with mouth forming second (GO:0001702)3.01940364
32glucocorticoid receptor signaling pathway (GO:0042921)3.00054765
33insulin-like growth factor receptor signaling pathway (GO:0048009)2.99676398
34macrophage activation involved in immune response (GO:0002281)2.99167852
35camera-type eye morphogenesis (GO:0048593)2.97947084
36plasma membrane repair (GO:0001778)2.97581876
37establishment of apical/basal cell polarity (GO:0035089)2.95297593
38negative regulation of fatty acid transport (GO:2000192)2.94813626
39regulation of chromatin binding (GO:0035561)2.94068345
40endothelial cell chemotaxis (GO:0035767)2.94062004
41cytoplasmic mRNA processing body assembly (GO:0033962)2.92203044
42negative regulation of cell size (GO:0045792)2.91777153
43regulation of somitogenesis (GO:0014807)2.86776765
44cell migration involved in sprouting angiogenesis (GO:0002042)2.86469585
45epithelial cell-cell adhesion (GO:0090136)2.86036477
46cell-substrate junction assembly (GO:0007044)2.85927549
47embryonic camera-type eye development (GO:0031076)2.83425123
48negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.78728613
49negative regulation of cell killing (GO:0031342)2.78728613
50coronary vasculature morphogenesis (GO:0060977)2.78136303
51regulation of p38MAPK cascade (GO:1900744)2.77178883
52positive regulation of epithelial to mesenchymal transition (GO:0010718)2.75569780
53neuron projection extension involved in neuron projection guidance (GO:1902284)2.74950439
54axon extension involved in axon guidance (GO:0048846)2.74950439
55cardiac myofibril assembly (GO:0055003)2.73739897
56regulation of SMAD protein import into nucleus (GO:0060390)2.71393669
57positive regulation of SMAD protein import into nucleus (GO:0060391)2.70626129
58heart valve formation (GO:0003188)2.70177970
59chondrocyte proliferation (GO:0035988)2.68484468
60negative regulation of toll-like receptor signaling pathway (GO:0034122)2.67637164
61modulation by virus of host process (GO:0019054)2.65354681
62histone H3-K36 demethylation (GO:0070544)2.65090253
63epithelial cell fate commitment (GO:0072148)2.64638826
64dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.64460510
65hemidesmosome assembly (GO:0031581)2.63829000
66negative regulation of glial cell proliferation (GO:0060253)2.63584629
67cell-substrate adherens junction assembly (GO:0007045)2.63559954
68focal adhesion assembly (GO:0048041)2.63559954
69cytoskeletal anchoring at plasma membrane (GO:0007016)2.63262269
70Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.62949018
71regulation of establishment of planar polarity (GO:0090175)2.62709759
72protein-DNA complex disassembly (GO:0032986)2.62341743
73nucleosome disassembly (GO:0006337)2.62341743
74trophectodermal cell differentiation (GO:0001829)2.62035705
75dosage compensation (GO:0007549)2.61628337
76establishment or maintenance of monopolar cell polarity (GO:0061339)2.61306639
77establishment of monopolar cell polarity (GO:0061162)2.61306639
78activation of MAPKKK activity (GO:0000185)2.60340140
79semaphorin-plexin signaling pathway (GO:0071526)2.59791247
80NLS-bearing protein import into nucleus (GO:0006607)2.58227423
81convergent extension (GO:0060026)2.58135512
82positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.57332101
83leukocyte migration involved in inflammatory response (GO:0002523)2.57265814
84blood vessel endothelial cell migration (GO:0043534)2.56665195
85regulation of NFAT protein import into nucleus (GO:0051532)2.56131333
86atrial septum morphogenesis (GO:0060413)2.55673460
87heart morphogenesis (GO:0003007)2.55293476
88regulation of tight junction assembly (GO:2000810)2.54725376
89detection of other organism (GO:0098543)2.54489110
90negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.53912405
91negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.53624984
92modulation by symbiont of host cellular process (GO:0044068)2.51980589
93anatomical structure regression (GO:0060033)2.51239665
94cochlea morphogenesis (GO:0090103)2.50392385
95dorsal/ventral axis specification (GO:0009950)2.49078748
96non-canonical Wnt signaling pathway (GO:0035567)2.48118656
97notochord development (GO:0030903)2.47968332
98negative regulation of chondrocyte differentiation (GO:0032331)2.46317676
99renal system development (GO:0072001)2.45988777
100cardiovascular system development (GO:0072358)2.45965811
101detection of molecule of bacterial origin (GO:0032490)2.45953798
102endocardial cushion development (GO:0003197)2.45809361
103apoptotic process involved in development (GO:1902742)2.45348745
104leukocyte aggregation (GO:0070486)2.45049562
105germ cell migration (GO:0008354)2.44238589
106detection of bacterium (GO:0016045)2.43834025
107positive regulation of Cdc42 GTPase activity (GO:0043089)2.43762972
108establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.43693444
109embryonic retina morphogenesis in camera-type eye (GO:0060059)2.43617082
110maternal placenta development (GO:0001893)2.42712098
111collecting duct development (GO:0072044)2.42085753
112protein heterotrimerization (GO:0070208)2.41761580
113corticosteroid receptor signaling pathway (GO:0031958)2.40236838
114tolerance induction (GO:0002507)2.38324870
115regulation of heart morphogenesis (GO:2000826)2.38104101
116basement membrane organization (GO:0071711)2.38081251
117tooth mineralization (GO:0034505)2.37281967
118endodermal cell differentiation (GO:0035987)2.37208073
119viral transcription (GO:0019083)2.37134106
120positive regulation of glycogen biosynthetic process (GO:0045725)2.37005757
121respiratory system process (GO:0003016)2.36991398
122eye morphogenesis (GO:0048592)2.36189956
123atrioventricular valve morphogenesis (GO:0003181)2.36154146
124vascular endothelial growth factor signaling pathway (GO:0038084)2.35980869
125cell migration involved in heart development (GO:0060973)2.35844396
126neural tube closure (GO:0001843)2.35555043
127sarcomere organization (GO:0045214)2.35409383
128regulation of mRNA stability (GO:0043488)2.35092503
129positive regulation of gene expression, epigenetic (GO:0045815)2.34085908
130positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.31887022
131cardiac muscle cell proliferation (GO:0060038)2.30670065
132regulation of gene silencing by RNA (GO:0060966)2.30646670
133regulation of posttranscriptional gene silencing (GO:0060147)2.30646670
134regulation of gene silencing by miRNA (GO:0060964)2.30646670
135positive regulation of RNA splicing (GO:0033120)2.30607253
136tube closure (GO:0060606)2.30095711
137aorta morphogenesis (GO:0035909)2.29412374
138negative regulation of cardiac muscle tissue growth (GO:0055022)2.28797254
139negative regulation of heart growth (GO:0061117)2.28797254
140negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.28602585
141lateral sprouting from an epithelium (GO:0060601)2.28279690
142detection of external biotic stimulus (GO:0098581)2.28117330
143detection of biotic stimulus (GO:0009595)2.28059186
144skin morphogenesis (GO:0043589)2.27991086
145epithelial cell differentiation involved in prostate gland development (GO:0060742)2.27799740
146regulation of T-helper 2 cell differentiation (GO:0045628)2.27473653
147antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.27283536
148regulation of phosphatidylinositol 3-kinase activity (GO:0043551)2.26999316
149mannose metabolic process (GO:0006013)2.26194540
150negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.23656771
151negative regulation of translation, ncRNA-mediated (GO:0040033)2.23656771
152regulation of translation, ncRNA-mediated (GO:0045974)2.23656771
153cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.22979609
154mRNA transcription from RNA polymerase II promoter (GO:0042789)2.22962104
155negative regulation of interleukin-12 production (GO:0032695)2.18698796
156negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.18609023
157positive regulation of fatty acid beta-oxidation (GO:0032000)2.18546438
158trabecula morphogenesis (GO:0061383)2.18057486
159regulation of apoptotic process involved in morphogenesis (GO:1902337)2.17720193
160peptidyl-tyrosine autophosphorylation (GO:0038083)2.16037743
161cellular extravasation (GO:0045123)2.14503734
162mammary gland epithelial cell differentiation (GO:0060644)2.13721406
163negative regulation of nucleotide catabolic process (GO:0030812)2.13102555
164negative regulation of granulocyte differentiation (GO:0030853)2.13079284
165regulation of ARF GTPase activity (GO:0032312)2.13011784
166macrophage activation (GO:0042116)2.12312118
167positive regulation by host of viral transcription (GO:0043923)2.11259919
168cellular response to virus (GO:0098586)2.09456393
169endothelial cell differentiation (GO:0045446)2.09442721
170regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.08635888
171regulation of early endosome to late endosome transport (GO:2000641)2.08135138
172mRNA transcription (GO:0009299)2.07320157
173antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.07217346
174positive regulation of protein deacetylation (GO:0090312)2.06473288
175negative regulation of phagocytosis (GO:0050765)2.03686057
176stress fiber assembly (GO:0043149)2.03586753
177positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.02961506
178negative regulation of myotube differentiation (GO:0010832)2.02936610

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.65705504
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.78128516
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.40354346
4STAT6_21828071_ChIP-Seq_BEAS2B_Human3.15679710
5MYC_22102868_ChIP-Seq_BL_Human3.07367676
6FOXM1_23109430_ChIP-Seq_U2OS_Human2.93316731
7ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.56340529
8* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.53591337
9* KDM2B_26808549_Chip-Seq_DND41_Human2.46972335
10* ZFP281_18757296_ChIP-ChIP_E14_Mouse2.43117630
11* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.42521840
12* TCF7_22412390_ChIP-Seq_EML_Mouse2.33648623
13* ELK3_25401928_ChIP-Seq_HUVEC_Human2.33060136
14STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.27089001
15* ZFP281_27345836_Chip-Seq_ESCs_Mouse2.25626356
16ERG_21242973_ChIP-ChIP_JURKAT_Human2.23365142
17* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.16455419
18* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.16129542
19SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.16010299
20TRIM28_21343339_ChIP-Seq_HEK293_Human2.10149954
21* RARG_19884340_ChIP-ChIP_MEFs_Mouse2.04779859
22* CLOCK_20551151_ChIP-Seq_293T_Human2.03913071
23* KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.03573383
24* VDR_24763502_ChIP-Seq_THP-1_Human1.92991743
25ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.92722155
26HIF1A_21447827_ChIP-Seq_MCF-7_Human1.92068676
27* KDM2B_26808549_Chip-Seq_K562_Human1.92024259
28* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.92015619
29* VDR_21846776_ChIP-Seq_THP-1_Human1.90028152
30* KDM2B_26808549_Chip-Seq_JURKAT_Human1.89537350
31* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.89344258
32TP63_19390658_ChIP-ChIP_HaCaT_Human1.85438426
33RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.84234695
34P300_27058665_Chip-Seq_ZR-75-30cells_Human1.83309024
35* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.83178267
36LXR_22292898_ChIP-Seq_THP-1_Human1.76485017
37RACK7_27058665_Chip-Seq_MCF-7_Human1.74773062
38VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.73020782
39SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.66559418
40NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.64229256
41TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.62111633
42ZNF263_19887448_ChIP-Seq_K562_Human1.61804991
43KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.60197444
44* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59431374
45* SA1_27219007_Chip-Seq_ERYTHROID_Human1.56334903
46ATF3_27146783_Chip-Seq_COLON_Human1.55561154
47UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.51751382
48* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.48564460
49* CTCF_27219007_Chip-Seq_Bcells_Human1.46349426
50P68_20966046_ChIP-Seq_HELA_Human1.46337879
51CREB1_26743006_Chip-Seq_LNCaP_Human1.45003416
52SUZ12_27294783_Chip-Seq_ESCs_Mouse1.44916464
53TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.43702406
54ISL1_27105846_Chip-Seq_CPCs_Mouse1.43221370
55NFIB_24661679_ChIP-Seq_LUNG_Mouse1.42780200
56EZH2_22144423_ChIP-Seq_EOC_Human1.42725150
57SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.40821948
58CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.39974203
59TP53_22127205_ChIP-Seq_IMR90_Human1.34927648
60RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.34171043
61DROSHA_22980978_ChIP-Seq_HELA_Human1.33439927
62E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.33393922
63TCF3_18692474_ChIP-Seq_MEFs_Mouse1.32704073
64RNF2_27304074_Chip-Seq_ESCs_Mouse1.32323381
65DNAJC2_21179169_ChIP-ChIP_NT2_Human1.31198591
66E2F7_22180533_ChIP-Seq_HELA_Human1.30181997
67TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.30153626
68* UTX_26944678_Chip-Seq_JUKART_Human1.29884007
69SMC4_20622854_ChIP-Seq_HELA_Human1.27781839
70* ESR2_21235772_ChIP-Seq_MCF-7_Human1.27746169
71EZH2_18974828_ChIP-Seq_MESCs_Mouse1.27721059
72RNF2_18974828_ChIP-Seq_MESCs_Mouse1.27721059
73EZH2_27294783_Chip-Seq_ESCs_Mouse1.27255329
74* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.27206193
75OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.27184209
76* RUNX1_27514584_Chip-Seq_MCF-7_Human1.26508131
77KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.26328268
78KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.26328268
79KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.26328268
80SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.23738406
81JARID2_20075857_ChIP-Seq_MESCs_Mouse1.23673667
82TP53_20018659_ChIP-ChIP_R1E_Mouse1.23359972
83* MAF_26560356_Chip-Seq_TH1_Human1.22726037
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.21045179
85* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.20194325
86* NCOR1_26117541_ChIP-Seq_K562_Human1.19905194
87* UBF1/2_26484160_Chip-Seq_HMECs_Human1.19279822
88KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.19149406
89ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.18767065
90* TET1_21451524_ChIP-Seq_MESCs_Mouse1.18650500
91MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.18407917
92FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.18342936
93GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.17321754
94SOX9_24532713_ChIP-Seq_HFSC_Mouse1.17143925
95MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.16534170
96* MAF_26560356_Chip-Seq_TH2_Human1.16288165
97STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.16117593
98* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.15754747
99* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.14423182
100* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.14141788
101* TBX20_22328084_ChIP-Seq_HEART_Mouse1.13693744
102* TBX20_22080862_ChIP-Seq_HEART_Mouse1.13693744
103BP1_19119308_ChIP-ChIP_Hs578T_Human1.13517885
104RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.13305809
105FOXO3_23340844_ChIP-Seq_DLD1_Human1.12902121
106EZH2_27304074_Chip-Seq_ESCs_Mouse1.12386550
107TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.10513895
108RING1B_27294783_Chip-Seq_ESCs_Mouse1.09824941
109JARID2_20064375_ChIP-Seq_MESCs_Mouse1.09385396
110CDX2_20551321_ChIP-Seq_CACO-2_Human1.09296431
111CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.08890842
112IKZF1_21737484_ChIP-ChIP_HCT116_Human1.08424591
113NANOG_21062744_ChIP-ChIP_HESCs_Human1.07105398
114SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.06119519
115RUNX1_22412390_ChIP-Seq_EML_Mouse1.04197250
116GATA6_25053715_ChIP-Seq_YYC3_Human1.04117126
117* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.04018940
118TCF3_18692474_ChIP-Seq_MESCs_Mouse1.03666388
119SA1_27219007_Chip-Seq_Bcells_Human1.03430832
120TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.03349628
121PKCTHETA_26484144_Chip-Seq_BREAST_Human1.02191699
122SALL1_21062744_ChIP-ChIP_HESCs_Human1.01264000
123ESR1_20079471_ChIP-ChIP_T-47D_Human1.01074533
124RING1B_27294783_Chip-Seq_NPCs_Mouse1.00397176
125PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.00340418
126* CHD1_26751641_Chip-Seq_LNCaP_Human0.99685098
127HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.98732812
128STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.98712702
129BRD4_25478319_ChIP-Seq_HGPS_Human0.98650857
130BCOR_27268052_Chip-Seq_Bcells_Human0.97738000
131POU5F1_16518401_ChIP-PET_MESCs_Mouse0.97069423
132* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.95935095
133SRY_22984422_ChIP-ChIP_TESTIS_Rat0.95850107
134SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95771125
135THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.95761642
136SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.95672240
137SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.95672240
138* TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.94915481
139PPAR_26484153_Chip-Seq_NCI-H1993_Human0.93736752
140CTCF_27219007_Chip-Seq_ERYTHROID_Human0.93249995
141DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.92719744
142OCT4_19829295_ChIP-Seq_ESCs_Human0.92653760
143EED_16625203_ChIP-ChIP_MESCs_Mouse0.92555485
144* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.92370155

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.15082367
2MP0009379_abnormal_foot_pigmentation3.48833945
3MP0010030_abnormal_orbit_morphology3.13597856
4MP0005076_abnormal_cell_differentiation2.98809860
5MP0003436_decreased_susceptibility_to2.98420577
6MP0009053_abnormal_anal_canal2.80550091
7MP0010352_gastrointestinal_tract_polyps2.58640256
8MP0004510_myositis2.51486383
9MP0000566_synostosis2.46695517
10MP0000537_abnormal_urethra_morphology2.44173705
11MP0005623_abnormal_meninges_morphology2.23764818
12MP0000733_abnormal_muscle_development2.22428112
13MP0005409_darkened_coat_color2.12083323
14MP0003566_abnormal_cell_adhesion2.10327809
15MP0003724_increased_susceptibility_to1.94676670
16MP0005377_hearing/vestibular/ear_phenot1.92801985
17MP0003878_abnormal_ear_physiology1.92801985
18MP0003385_abnormal_body_wall1.91061364
19MP0002254_reproductive_system_inflammat1.90703994
20MP0009278_abnormal_bone_marrow1.82357214
21MP0001849_ear_inflammation1.78662388
22MP0008438_abnormal_cutaneous_collagen1.78209280
23MP0003115_abnormal_respiratory_system1.76050692
24MP0004272_abnormal_basement_membrane1.73977115
25MP0002653_abnormal_ependyma_morphology1.73913095
26MP0010368_abnormal_lymphatic_system1.73820675
27MP0000428_abnormal_craniofacial_morphol1.61614669
28MP0008961_abnormal_basal_metabolism1.59630922
29MP0004197_abnormal_fetal_growth/weight/1.57464208
30MP0003300_gastrointestinal_ulcer1.57263942
31MP0000678_abnormal_parathyroid_gland1.55258237
32MP0005248_abnormal_Harderian_gland1.54252070
33MP0002249_abnormal_larynx_morphology1.52660131
34MP0003119_abnormal_digestive_system1.52245808
35MP0003279_aneurysm1.51567944
36MP0003935_abnormal_craniofacial_develop1.51164263
37MP0005275_abnormal_skin_tensile1.49777846
38MP0002277_abnormal_respiratory_mucosa1.48624399
39MP0002998_abnormal_bone_remodeling1.47978330
40MP0003941_abnormal_skin_development1.47780676
41MP0003567_abnormal_fetal_cardiomyocyte1.47660308
42MP0004133_heterotaxia1.46833755
43MP0003942_abnormal_urinary_system1.45502805
44MP0000534_abnormal_ureter_morphology1.45382127
45MP0003091_abnormal_cell_migration1.44442163
46MP0010630_abnormal_cardiac_muscle1.44183564
47MP0002419_abnormal_innate_immunity1.43947721
48MP0005257_abnormal_intraocular_pressure1.43857021
49MP0002925_abnormal_cardiovascular_devel1.41092900
50MP0002084_abnormal_developmental_patter1.39403301
51MP0003755_abnormal_palate_morphology1.37807630
52MP0009840_abnormal_foam_cell1.34988438
53MP0004084_abnormal_cardiac_muscle1.34576437
54MP0002932_abnormal_joint_morphology1.34397259
55MP0001533_abnormal_skeleton_physiology1.34192985
56MP0002085_abnormal_embryonic_tissue1.33499028
57MP0005023_abnormal_wound_healing1.33264570
58MP0002088_abnormal_embryonic_growth/wei1.33185811
59MP0000750_abnormal_muscle_regeneration1.33152649
60MP0003984_embryonic_growth_retardation1.32280757
61MP0000049_abnormal_middle_ear1.32076164
62MP0000767_abnormal_smooth_muscle1.29279759
63MP0005380_embryogenesis_phenotype1.27839503
64MP0001672_abnormal_embryogenesis/_devel1.27839503
65MP0003122_maternal_imprinting1.27774847
66MP0010234_abnormal_vibrissa_follicle1.26789450
67MP0002086_abnormal_extraembryonic_tissu1.26482170
68MP0003172_abnormal_lysosome_physiology1.26464099
69MP0002132_abnormal_respiratory_system1.25976932
70MP0002282_abnormal_trachea_morphology1.25702250
71MP0004947_skin_inflammation1.25656775
72MP0002697_abnormal_eye_size1.25169692
73MP0004087_abnormal_muscle_fiber1.21915430
74MP0006054_spinal_hemorrhage1.20519619
75MP0005025_abnormal_response_to1.19184660
76MP0002234_abnormal_pharynx_morphology1.18881196
77MP0002138_abnormal_hepatobiliary_system1.18456530
78MP0003283_abnormal_digestive_organ1.18443511
79MP0004233_abnormal_muscle_weight1.17383923
80MP0005390_skeleton_phenotype1.14074785
81MP0009250_abnormal_appendicular_skeleto1.13293781
82MP0001915_intracranial_hemorrhage1.12800441
83MP0000751_myopathy1.12706314
84MP0005508_abnormal_skeleton_morphology1.12690548
85MP0002116_abnormal_craniofacial_bone1.12374257
86MP0000778_abnormal_nervous_system1.11921291
87MP0000432_abnormal_head_morphology1.11631702
88MP0001790_abnormal_immune_system1.11599487
89MP0005387_immune_system_phenotype1.11599487
90MP0001348_abnormal_lacrimal_gland1.11371217
91MP0001730_embryonic_growth_arrest1.11102997
92MP0003303_peritoneal_inflammation1.09910950
93MP0005187_abnormal_penis_morphology1.09643253
94MP0005367_renal/urinary_system_phenotyp1.08366876
95MP0000516_abnormal_urinary_system1.08366876
96MP0001697_abnormal_embryo_size1.08285600
97MP0002092_abnormal_eye_morphology1.08246900
98MP0000266_abnormal_heart_morphology1.07062848
99MP0003937_abnormal_limbs/digits/tail_de1.06417900
100MP0002089_abnormal_postnatal_growth/wei1.06113511
101MP0003828_pulmonary_edema1.03296905
102MP0005451_abnormal_body_composition1.03231802
103MP0002877_abnormal_melanocyte_morpholog1.02899160
104MP0003938_abnormal_ear_development1.02512567
105MP0006292_abnormal_olfactory_placode1.02423695
106MP0000350_abnormal_cell_proliferation1.02228724
107MP0003123_paternal_imprinting1.01717975
108MP0001663_abnormal_digestive_system1.01291963
109MP0001958_emphysema1.00272079
110MP0000858_altered_metastatic_potential0.99053193
111MP0005503_abnormal_tendon_morphology0.97416120
112MP0003121_genomic_imprinting0.97150727
113MP0004808_abnormal_hematopoietic_stem0.97127016
114MP0004264_abnormal_extraembryonic_tissu0.95801223
115MP0002128_abnormal_blood_circulation0.95793322
116MP0005381_digestive/alimentary_phenotyp0.95616003
117MP0002111_abnormal_tail_morphology0.95003635
118MP0001614_abnormal_blood_vessel0.94501976
119MP0006138_congestive_heart_failure0.94298521
120MP0002233_abnormal_nose_morphology0.93712158
121MP0002796_impaired_skin_barrier0.92874438
122MP0000467_abnormal_esophagus_morphology0.90910222
123MP0004858_abnormal_nervous_system0.90442159
124MP0003453_abnormal_keratinocyte_physiol0.89780665
125MP0005666_abnormal_adipose_tissue0.88758812
126MP0001286_abnormal_eye_development0.88536681
127MP0003890_abnormal_embryonic-extraembry0.88348653
128MP0002405_respiratory_system_inflammati0.88125682
129MP0000762_abnormal_tongue_morphology0.87531417
130MP0001784_abnormal_fluid_regulation0.86873112
131MP0009384_cardiac_valve_regurgitation0.86364443
132MP0004185_abnormal_adipocyte_glucose0.86337032
133MP0009672_abnormal_birth_weight0.86076230
134MP0009703_decreased_birth_body0.85691120
135MP0003861_abnormal_nervous_system0.85097394
136MP0002896_abnormal_bone_mineralization0.84902166
137MP0000685_abnormal_immune_system0.84901201
138MP0001800_abnormal_humoral_immune0.84882899
139MP0004130_abnormal_muscle_cell0.83075160
140MP0005000_abnormal_immune_tolerance0.82152883
141MP0000490_abnormal_crypts_of0.81163076
142MP0000470_abnormal_stomach_morphology0.80438776
143MP0001502_abnormal_circadian_rhythm0.80427985
144MP0002452_abnormal_antigen_presenting0.78583506
145MP0006082_CNS_inflammation0.77052559
146MP0008260_abnormal_autophagy0.75741348
147MP0001819_abnormal_immune_cell0.74754799
148MP0002420_abnormal_adaptive_immunity0.74059454
149MP0003315_abnormal_perineum_morphology0.73483886
150MP0002723_abnormal_immune_serum0.73000374
151MP0001545_abnormal_hematopoietic_system0.72965620
152MP0005397_hematopoietic_system_phenotyp0.72965620
153MP0005375_adipose_tissue_phenotype0.72793259
154MP0005058_abnormal_lysosome_morphology0.72244508
155MP0004883_abnormal_blood_vessel0.71670331
156MP0003948_abnormal_gas_homeostasis0.69582628
157MP0003329_amyloid_beta_deposits0.69243741
158MP0004381_abnormal_hair_follicle0.68588975
159MP0003690_abnormal_glial_cell0.68561820
160MP0010155_abnormal_intestine_physiology0.65847871

Predicted human phenotypes

RankGene SetZ-score
1Obstructive sleep apnea (HP:0002870)4.34690454
2Shallow orbits (HP:0000586)4.00585108
3Short 4th metacarpal (HP:0010044)3.86112726
4Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.86112726
5Protrusio acetabuli (HP:0003179)3.64935924
6Abnormality of the 4th metacarpal (HP:0010012)3.32016016
7Eczematoid dermatitis (HP:0000976)3.27041648
8Partial duplication of thumb phalanx (HP:0009944)3.22799798
9Hyperacusis (HP:0010780)3.15078803
10Renal duplication (HP:0000075)3.07560376
11Cerebral aneurysm (HP:0004944)3.03874714
12Partial duplication of the phalanx of hand (HP:0009999)2.93013905
13Broad face (HP:0000283)2.73046358
14Segmental peripheral demyelination/remyelination (HP:0003481)2.71687587
15Increased connective tissue (HP:0009025)2.71520976
16Abnormality of the aortic arch (HP:0012303)2.65015169
17Long palpebral fissure (HP:0000637)2.55745190
18Premature rupture of membranes (HP:0001788)2.55501029
19Myositis (HP:0100614)2.52519803
20Abnormality of macrophages (HP:0004311)2.51250451
21Increased IgE level (HP:0003212)2.51168668
22Orchitis (HP:0100796)2.49147050
23Right ventricular cardiomyopathy (HP:0011663)2.48690130
24Bladder diverticulum (HP:0000015)2.44849507
25Lymphangioma (HP:0100764)2.43238726
26Ankle contracture (HP:0006466)2.40635316
27Recurrent gram-negative bacterial infections (HP:0005420)2.39742886
28Mitral valve prolapse (HP:0001634)2.39585467
29Broad metatarsal (HP:0001783)2.36458996
30Increased density of long bones (HP:0006392)2.35676928
31Recurrent bacterial skin infections (HP:0005406)2.34539719
32Supernumerary bones of the axial skeleton (HP:0009144)2.32085004
33Rectal prolapse (HP:0002035)2.31424890
34Elfin facies (HP:0004428)2.30701703
35Deviation of the hallux (HP:0010051)2.26224799
36Renovascular hypertension (HP:0100817)2.23064685
37Genu recurvatum (HP:0002816)2.21478089
38Wrist flexion contracture (HP:0001239)2.21333818
39Anomalous pulmonary venous return (HP:0010772)2.21197226
40Hallux valgus (HP:0001822)2.20173880
41Metaphyseal cupping (HP:0003021)2.20083093
42Nasal polyposis (HP:0100582)2.19085211
43Recurrent abscess formation (HP:0002722)2.17959550
44Abnormality of the nasal mucosa (HP:0000433)2.17885439
45Aneurysm (HP:0002617)2.10677754
46Increased nuchal translucency (HP:0010880)2.09572316
47Pseudobulbar signs (HP:0002200)2.08358924
48Bowel diverticulosis (HP:0005222)2.08183559
49Mildly elevated creatine phosphokinase (HP:0008180)2.07273067
50Aortic aneurysm (HP:0004942)2.06795724
51Abnormal number of incisors (HP:0011064)2.06490498
52Thin ribs (HP:0000883)2.06313103
53Abnormality of the pulmonary veins (HP:0011718)2.06133635
54Asymmetry of the thorax (HP:0001555)2.05598578
55Atrophic scars (HP:0001075)2.05244191
56Retrobulbar optic neuritis (HP:0100654)2.04535284
57Optic neuritis (HP:0100653)2.04535284
58Ulnar bowing (HP:0003031)2.02174819
59Difficulty climbing stairs (HP:0003551)2.01682915
60Abnormality of the parietal bone (HP:0002696)2.01520573
61Trigonocephaly (HP:0000243)2.01099368
62Ventricular tachycardia (HP:0004756)2.00077093
63Broad thumb (HP:0011304)1.98362861
64Dilatation of the ascending aorta (HP:0005111)1.96854438
65Camptodactyly of toe (HP:0001836)1.96783908
66Long eyelashes (HP:0000527)1.96155647
67Septo-optic dysplasia (HP:0100842)1.94644560
68Subacute progressive viral hepatitis (HP:0006572)1.94299453
69Abnormal vertebral ossification (HP:0100569)1.94047225
70Flat cornea (HP:0007720)1.93480947
71Sleep apnea (HP:0010535)1.93041952
72Deep palmar crease (HP:0006191)1.90404455
73Coronal craniosynostosis (HP:0004440)1.89805366
74Spinal cord lesions (HP:0100561)1.89518396
75Syringomyelia (HP:0003396)1.89518396
76Overriding aorta (HP:0002623)1.88235266
77Disproportionate tall stature (HP:0001519)1.87437036
78Gingivitis (HP:0000230)1.87423443
79Enlarged penis (HP:0000040)1.85850597
80Polygenic inheritance (HP:0010982)1.85820342
81Hypercortisolism (HP:0001578)1.83921829
82Type 1 muscle fiber predominance (HP:0003803)1.83823543
83Abnormality of the distal phalanx of the thumb (HP:0009617)1.83461213
84Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.83342014
85Peritonitis (HP:0002586)1.83036405
86Thin bony cortex (HP:0002753)1.82499215
87Macroorchidism (HP:0000053)1.82251401
88Mitral regurgitation (HP:0001653)1.81939657
89Difficulty running (HP:0009046)1.81766332
90Aortic dissection (HP:0002647)1.81680899
91Deviation of the thumb (HP:0009603)1.81047363
92Hyporeflexia of lower limbs (HP:0002600)1.81000780
93Chronic obstructive pulmonary disease (HP:0006510)1.80488102
94Obstructive lung disease (HP:0006536)1.80488102
95Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.78901639
96Broad toe (HP:0001837)1.78297457
97Hepatoblastoma (HP:0002884)1.77770857
98Skull defect (HP:0001362)1.76516465
99Abnormality of the phalanges of the hallux (HP:0010057)1.75664369
100Broad phalanges of the hand (HP:0009768)1.75512140
101Wide anterior fontanel (HP:0000260)1.74660036
102Fragile skin (HP:0001030)1.74593095
103Arnold-Chiari malformation (HP:0002308)1.74415906
104Pointed chin (HP:0000307)1.73658601
105Easy fatigability (HP:0003388)1.73347895
106Distal upper limb amyotrophy (HP:0007149)1.72618655
107Upper limb amyotrophy (HP:0009129)1.72618655
108Mediastinal lymphadenopathy (HP:0100721)1.72191563
109Shawl scrotum (HP:0000049)1.71797176
110Neurofibrillary tangles (HP:0002185)1.71781392
111Nasolacrimal duct obstruction (HP:0000579)1.70983999
112Precocious puberty (HP:0000826)1.70713544
113Supernumerary ribs (HP:0005815)1.70597745
114Malignant gastrointestinal tract tumors (HP:0006749)1.70408250
115Gastrointestinal carcinoma (HP:0002672)1.70408250
116Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.70239356
117Sudden death (HP:0001699)1.70028639
118Scapular winging (HP:0003691)1.69962552
119Neonatal hypoglycemia (HP:0001998)1.69738470
120Abnormality of the nasal septum (HP:0000419)1.69322500
121Broad hallux (HP:0010055)1.69246833
122Milia (HP:0001056)1.69109224
123Spontaneous hematomas (HP:0007420)1.69095993
124Broad finger (HP:0001500)1.68917225
125Distal lower limb muscle weakness (HP:0009053)1.68661692
126Short phalanx of the thumb (HP:0009660)1.66920742
127Distal lower limb amyotrophy (HP:0008944)1.66408476
128Cellulitis (HP:0100658)1.65764866
129Spinal rigidity (HP:0003306)1.65619757
130Heterotopia (HP:0002282)1.65526505
131Abnormality of the incisor (HP:0000676)1.65119556
132Aplasia involving bones of the extremities (HP:0009825)1.65095437
133Aplasia involving bones of the upper limbs (HP:0009823)1.65095437
134Aplasia of the phalanges of the hand (HP:0009802)1.65095437
135Proximal placement of thumb (HP:0009623)1.64538542
136Short 1st metacarpal (HP:0010034)1.63962266
137Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.63962266
138Abnormality of the diencephalon (HP:0010662)1.63937396
139Urethral obstruction (HP:0000796)1.63764053
140Hypochromic anemia (HP:0001931)1.63709306
141Bicuspid aortic valve (HP:0001647)1.63524646
142Abnormality of the intervertebral disk (HP:0005108)1.63333800
143Stereotypic behavior (HP:0000733)1.62882310
144Insomnia (HP:0100785)1.62284571
145Elevated erythrocyte sedimentation rate (HP:0003565)1.61880085
146Spina bifida occulta (HP:0003298)1.61308765
147Rib fusion (HP:0000902)1.61303385
148Uterine leiomyosarcoma (HP:0002891)1.61251843
149Leiomyosarcoma (HP:0100243)1.61251843
150Abnormality of the fingertips (HP:0001211)1.60713605
151Hemorrhage of the eye (HP:0011885)1.60317725
152Abnormality of the columella (HP:0009929)1.59561638
153Muscle fiber splitting (HP:0003555)1.59321693
154Blue sclerae (HP:0000592)1.59252769
155Gastrointestinal infarctions (HP:0005244)1.59226822
156Bronchomalacia (HP:0002780)1.59218926
157Short 5th finger (HP:0009237)1.58969699
158Increased cerebral lipofuscin (HP:0011813)1.58795832
159Persistence of primary teeth (HP:0006335)1.58533803
160Deep venous thrombosis (HP:0002625)1.58412066
161Axonal loss (HP:0003447)1.58156486
162Selective tooth agenesis (HP:0001592)1.57724459
163Buphthalmos (HP:0000557)1.56400017
164Fibroma (HP:0010614)1.55983944
165Germ cell neoplasia (HP:0100728)1.55850322
166Turricephaly (HP:0000262)1.55827626

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.16428615
2MAP3K103.87211160
3CDK123.69411244
4PKN23.41832860
5EEF2K3.16675669
6LATS12.72567552
7TTN2.65327473
8EPHB22.56625109
9RIPK12.44532006
10PRPF4B2.41641074
11SMG12.34732080
12PDGFRA2.30735358
13ICK2.20185344
14ERN12.16139902
15PTK62.04544379
16LATS22.00766381
17MAPK151.92417152
18SIK11.82198094
19DMPK1.80633192
20MAP2K31.65552444
21IRAK41.64584134
22DDR21.61631717
23MAP3K111.58926072
24MTOR1.55008278
25BMX1.50024325
26PAK41.42306579
27BLK1.35406267
28EPHA21.31021943
29PTK21.28188188
30CDK61.26640866
31STK101.24441559
32TYRO31.23603347
33LRRK21.17428522
34MAP3K31.16836084
35CAMK1G1.15334494
36PAK21.14095089
37RPS6KB21.11926605
38ALK1.10211537
39RIPK41.09417087
40EPHA31.08192683
41EPHB11.07958186
42SIK21.07179572
43FGFR11.05988163
44CAMK1D1.05844073
45BRD41.05756036
46TAOK11.05443653
47FGFR31.05278715
48DYRK31.04037270
49TNK21.03310454
50FGFR41.02022399
51MAP3K11.01114754
52DYRK1B1.00645929
53PDGFRB0.99886613
54ZAP700.98626063
55IRAK20.93515726
56IRAK30.91128620
57NEK20.90773283
58TAOK20.90667367
59TGFBR20.89237982
60ERBB20.88160395
61MAP3K130.86273153
62STK30.86102310
63TGFBR10.86093727
64CDK40.83471223
65ILK0.82215344
66MAP3K70.77951834
67DYRK20.75631848
68FER0.73695514
69SGK4940.72524344
70SGK2230.72524344
71KSR20.72410349
72MAPK70.71073135
73FES0.70076622
74PRKD30.69396628
75MATK0.69287848
76GRK60.67570254
77MAP3K90.67066156
78IRAK10.66875745
79FGFR20.66347493
80FGR0.64819710
81PRKD20.62516617
82TNIK0.62458985
83LMTK20.62358353
84CDK70.61267407
85UHMK10.60909317
86SIK30.60093611
87STK110.59993113
88RET0.59693957
89MARK20.58697552
90PDPK10.57698377
91ROCK10.57098392
92MAPK120.57046074
93HCK0.56679572
94MAP3K60.56329799
95CHUK0.56192888
96RPS6KA10.55433758
97SGK20.55005692
98RPS6KA20.54931650
99TYK20.54474191
100TBK10.54184718
101PRKCZ0.53812637
102MAP3K80.53597148
103AKT20.53513210
104NEK10.53102468
105BTK0.53052279
106NTRK20.52194429
107KSR10.50553974
108CDC42BPA0.50514501
109PRKD10.50416116
110RPS6KA40.49747943
111PAK30.48949459
112RPS6KC10.46889419
113RPS6KL10.46889419
114GSK3A0.46317201
115TESK10.46125912
116SCYL20.45454956
117HIPK20.44935332
118MAPKAPK30.43326403
119CDK90.43241426
120MAP2K20.42396402
121PRKG20.41923036
122MAPK40.40545221
123PNCK0.40504127
124CDC70.39941171
125PIM10.39899285
126MARK10.39709534
127CAMK40.39692247
128WNK10.39556872
129RPS6KA60.37145126
130IKBKB0.36813139
131CDK20.36605839
132AKT10.36254904
133MAPK10.35967875
134MAPKAPK20.34786416
135CHEK10.34326205
136MAPK90.33189610
137PRKAA10.32448323
138STK40.31819287
139CSK0.31125470
140ERBB30.30179161
141PRKCH0.29937003
142SGK30.29776577
143MAPK80.29393058
144MAP4K10.28817019
145ROCK20.28578404
146STK38L0.28225158
147TESK20.27700104

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052172.51429116
2Adherens junction_Homo sapiens_hsa045202.37492323
3Notch signaling pathway_Homo sapiens_hsa043302.26062107
4Hippo signaling pathway_Homo sapiens_hsa043902.05080890
5Chronic myeloid leukemia_Homo sapiens_hsa052202.04702962
6MicroRNAs in cancer_Homo sapiens_hsa052062.02356005
7Proteoglycans in cancer_Homo sapiens_hsa052051.93052991
8Viral myocarditis_Homo sapiens_hsa054161.86944150
9Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.85112707
10Focal adhesion_Homo sapiens_hsa045101.85106878
11Lysine degradation_Homo sapiens_hsa003101.83380001
12Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.81696005
13Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.79163971
14Bladder cancer_Homo sapiens_hsa052191.75385139
15Small cell lung cancer_Homo sapiens_hsa052221.75110683
16Hedgehog signaling pathway_Homo sapiens_hsa043401.74824442
17Endometrial cancer_Homo sapiens_hsa052131.71444766
18Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.64942179
19ECM-receptor interaction_Homo sapiens_hsa045121.64491070
20Colorectal cancer_Homo sapiens_hsa052101.57508384
21Dilated cardiomyopathy_Homo sapiens_hsa054141.55160862
22Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.51080578
23mTOR signaling pathway_Homo sapiens_hsa041501.45296016
24AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.41533327
25Toll-like receptor signaling pathway_Homo sapiens_hsa046201.39802495
26Leishmaniasis_Homo sapiens_hsa051401.39313058
27Thyroid hormone signaling pathway_Homo sapiens_hsa049191.37431680
28Prion diseases_Homo sapiens_hsa050201.30837647
29Renal cell carcinoma_Homo sapiens_hsa052111.30200476
30Pancreatic cancer_Homo sapiens_hsa052121.28507517
31Leukocyte transendothelial migration_Homo sapiens_hsa046701.27299532
32TGF-beta signaling pathway_Homo sapiens_hsa043501.26967765
33Tight junction_Homo sapiens_hsa045301.26933559
34Non-small cell lung cancer_Homo sapiens_hsa052231.26477245
35Wnt signaling pathway_Homo sapiens_hsa043101.26399144
36Central carbon metabolism in cancer_Homo sapiens_hsa052301.25552877
37HTLV-I infection_Homo sapiens_hsa051661.24353229
38Axon guidance_Homo sapiens_hsa043601.23647986
39Dorso-ventral axis formation_Homo sapiens_hsa043201.23047579
40Malaria_Homo sapiens_hsa051441.20720820
41Acute myeloid leukemia_Homo sapiens_hsa052211.19210983
42Chemokine signaling pathway_Homo sapiens_hsa040621.18803664
43Pathways in cancer_Homo sapiens_hsa052001.18579435
44Glioma_Homo sapiens_hsa052141.17998794
45Staphylococcus aureus infection_Homo sapiens_hsa051501.17685934
46Regulation of actin cytoskeleton_Homo sapiens_hsa048101.17162189
47Amoebiasis_Homo sapiens_hsa051461.16794626
48Insulin resistance_Homo sapiens_hsa049311.15055385
49GnRH signaling pathway_Homo sapiens_hsa049121.14025133
50Neurotrophin signaling pathway_Homo sapiens_hsa047221.13881771
51VEGF signaling pathway_Homo sapiens_hsa043701.13458507
52Prostate cancer_Homo sapiens_hsa052151.10628065
53Hepatitis C_Homo sapiens_hsa051601.05363906
54Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.05106194
55Thyroid cancer_Homo sapiens_hsa052161.03395306
56mRNA surveillance pathway_Homo sapiens_hsa030151.03296181
57Transcriptional misregulation in cancer_Homo sapiens_hsa052021.01284668
58Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.98207558
59Longevity regulating pathway - mammal_Homo sapiens_hsa042110.96987021
60Other glycan degradation_Homo sapiens_hsa005110.96287163
61Tuberculosis_Homo sapiens_hsa051520.95402915
62Toxoplasmosis_Homo sapiens_hsa051450.95279833
63Rap1 signaling pathway_Homo sapiens_hsa040150.94461621
64Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.93369585
65Insulin signaling pathway_Homo sapiens_hsa049100.91641967
66Melanogenesis_Homo sapiens_hsa049160.90819532
67NOD-like receptor signaling pathway_Homo sapiens_hsa046210.90018424
68Estrogen signaling pathway_Homo sapiens_hsa049150.89734757
69Viral carcinogenesis_Homo sapiens_hsa052030.89425746
70FoxO signaling pathway_Homo sapiens_hsa040680.89050551
71p53 signaling pathway_Homo sapiens_hsa041150.88072680
72Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.87972320
73Influenza A_Homo sapiens_hsa051640.87853144
74AMPK signaling pathway_Homo sapiens_hsa041520.87713937
75NF-kappa B signaling pathway_Homo sapiens_hsa040640.86205115
76Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.85491861
77Protein digestion and absorption_Homo sapiens_hsa049740.85421881
78HIF-1 signaling pathway_Homo sapiens_hsa040660.85420890
79Carbohydrate digestion and absorption_Homo sapiens_hsa049730.84645278
80Melanoma_Homo sapiens_hsa052180.82189819
81Prolactin signaling pathway_Homo sapiens_hsa049170.81716266
82PI3K-Akt signaling pathway_Homo sapiens_hsa041510.81206665
83Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.80714264
84Hepatitis B_Homo sapiens_hsa051610.78719675
85ErbB signaling pathway_Homo sapiens_hsa040120.77553514
86Platelet activation_Homo sapiens_hsa046110.76188108
87Cell cycle_Homo sapiens_hsa041100.75315096
88Apoptosis_Homo sapiens_hsa042100.72385317
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.71834615
90MAPK signaling pathway_Homo sapiens_hsa040100.67356645
91Shigellosis_Homo sapiens_hsa051310.66442830
92Cocaine addiction_Homo sapiens_hsa050300.65853855
93B cell receptor signaling pathway_Homo sapiens_hsa046620.64957175
94Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64470120
95Ras signaling pathway_Homo sapiens_hsa040140.64031734
96Gap junction_Homo sapiens_hsa045400.63157708
97African trypanosomiasis_Homo sapiens_hsa051430.62785103
98Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.62196434
99Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.62169688
100Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.62093207
101Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.61550424
102Glucagon signaling pathway_Homo sapiens_hsa049220.59523700
103Osteoclast differentiation_Homo sapiens_hsa043800.59194193
104Jak-STAT signaling pathway_Homo sapiens_hsa046300.58518420
105Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57886419
106Type II diabetes mellitus_Homo sapiens_hsa049300.57776310
107Pertussis_Homo sapiens_hsa051330.57430043
108Cholinergic synapse_Homo sapiens_hsa047250.57245165
109Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.57183452
110TNF signaling pathway_Homo sapiens_hsa046680.57182085
111Ribosome_Homo sapiens_hsa030100.56870412
1122-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.56538799
113Adipocytokine signaling pathway_Homo sapiens_hsa049200.56345011
114Fat digestion and absorption_Homo sapiens_hsa049750.56322841
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.56019991
116Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.55661570
117Endocytosis_Homo sapiens_hsa041440.53861591
118Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.53736283
119Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.52696158
120cAMP signaling pathway_Homo sapiens_hsa040240.52307980
121Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.52201693
122Salmonella infection_Homo sapiens_hsa051320.51533861
123Phospholipase D signaling pathway_Homo sapiens_hsa040720.49223292
124Spliceosome_Homo sapiens_hsa030400.47806843
125Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.47250774
126Choline metabolism in cancer_Homo sapiens_hsa052310.46539880
127cGMP-PKG signaling pathway_Homo sapiens_hsa040220.45368580
128Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.44908820
129T cell receptor signaling pathway_Homo sapiens_hsa046600.44439381
130Renin-angiotensin system_Homo sapiens_hsa046140.43304821

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