MIER3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)6.64955481
2mitotic sister chromatid cohesion (GO:0007064)5.50841202
3purine nucleobase biosynthetic process (GO:0009113)5.47591432
4metaphase plate congression (GO:0051310)5.45393037
5microtubule depolymerization (GO:0007019)5.08489061
6pre-miRNA processing (GO:0031054)4.98558491
7regulation of spindle organization (GO:0090224)4.83294994
8monoubiquitinated protein deubiquitination (GO:0035520)4.67120530
9nucleobase biosynthetic process (GO:0046112)4.61796623
10establishment of chromosome localization (GO:0051303)4.48189226
11maturation of 5.8S rRNA (GO:0000460)4.44770752
12attachment of spindle microtubules to kinetochore (GO:0008608)4.41347981
13regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.39692805
14protein localization to kinetochore (GO:0034501)4.35327091
15DNA replication checkpoint (GO:0000076)4.24516347
16transcription from RNA polymerase I promoter (GO:0006360)4.21622759
17transcription initiation from RNA polymerase I promoter (GO:0006361)4.19388272
18termination of RNA polymerase I transcription (GO:0006363)4.18462858
19ribosome biogenesis (GO:0042254)4.16663223
207-methylguanosine mRNA capping (GO:0006370)4.15598044
21positive regulation of chromosome segregation (GO:0051984)4.14643572
22RNA capping (GO:0036260)4.13927087
237-methylguanosine RNA capping (GO:0009452)4.13927087
24transcription elongation from RNA polymerase I promoter (GO:0006362)4.11989418
25vitamin transmembrane transport (GO:0035461)4.08318479
26termination of RNA polymerase III transcription (GO:0006386)4.01595916
27transcription elongation from RNA polymerase III promoter (GO:0006385)4.01595916
28mitotic chromosome condensation (GO:0007076)3.96480051
29spindle checkpoint (GO:0031577)3.91193226
30CENP-A containing nucleosome assembly (GO:0034080)3.90793920
31rRNA modification (GO:0000154)3.88356277
32regulation of sister chromatid cohesion (GO:0007063)3.85502719
33heterochromatin organization (GO:0070828)3.83659003
34sister chromatid segregation (GO:0000819)3.82483192
35regulation of mitotic spindle organization (GO:0060236)3.81651430
36protein localization to chromosome, centromeric region (GO:0071459)3.78663792
37meiosis I (GO:0007127)3.76534045
38maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.74098247
39DNA unwinding involved in DNA replication (GO:0006268)3.70542454
40regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.68639050
41chromatin remodeling at centromere (GO:0031055)3.65290661
42nuclear pore organization (GO:0006999)3.63227084
43male meiosis I (GO:0007141)3.62834377
44non-recombinational repair (GO:0000726)3.62820480
45double-strand break repair via nonhomologous end joining (GO:0006303)3.62820480
46regulation of centriole replication (GO:0046599)3.61176109
47regulation of RNA export from nucleus (GO:0046831)3.60130944
48regulation of transcription from RNA polymerase I promoter (GO:0006356)3.59983112
49nuclear pore complex assembly (GO:0051292)3.59449611
50histone exchange (GO:0043486)3.59431436
51paraxial mesoderm development (GO:0048339)3.58784080
52regulation of G0 to G1 transition (GO:0070316)3.57826028
53oocyte maturation (GO:0001556)3.54717943
54protein K6-linked ubiquitination (GO:0085020)3.54594396
55positive regulation of mitotic sister chromatid separation (GO:1901970)3.52123967
56positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.52123967
57positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.52123967
58rRNA methylation (GO:0031167)3.52099274
59negative regulation of fibroblast apoptotic process (GO:2000270)3.52080276
60inner cell mass cell proliferation (GO:0001833)3.51759291
61meiotic chromosome segregation (GO:0045132)3.50531915
62transcription elongation from RNA polymerase II promoter (GO:0006368)3.50438407
63kinetochore assembly (GO:0051382)3.47454018
64regulation of DNA methylation (GO:0044030)3.45954374
65regulation of chromosome segregation (GO:0051983)3.45019455
66negative regulation of DNA-dependent DNA replication (GO:2000104)3.44251415
67DNA-templated transcription, elongation (GO:0006354)3.43159943
68ribosome assembly (GO:0042255)3.42815576
69regulation of mitotic metaphase/anaphase transition (GO:0030071)3.42384045
70DNA replication-independent nucleosome organization (GO:0034724)3.42227497
71DNA replication-independent nucleosome assembly (GO:0006336)3.42227497
72regulation of DNA endoreduplication (GO:0032875)3.41158259
73nuclear envelope disassembly (GO:0051081)3.38031164
74membrane disassembly (GO:0030397)3.38031164
75bundle of His cell to Purkinje myocyte communication (GO:0086069)3.36976841
76replication fork processing (GO:0031297)3.36650292
77mitotic spindle checkpoint (GO:0071174)3.35151509
78regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.34796784
79kinetochore organization (GO:0051383)3.29172743
80DNA double-strand break processing (GO:0000729)3.28984211
81mitotic sister chromatid segregation (GO:0000070)3.28980382
82resolution of meiotic recombination intermediates (GO:0000712)3.28365725
83DNA synthesis involved in DNA repair (GO:0000731)3.28273627
84synaptonemal complex assembly (GO:0007130)3.26573653
85poly(A)+ mRNA export from nucleus (GO:0016973)3.22644660
86regulation of double-strand break repair via homologous recombination (GO:0010569)3.21795735
87regulation of nuclear cell cycle DNA replication (GO:0033262)3.20020305
88regulation of sister chromatid segregation (GO:0033045)3.18611855
89regulation of mitotic sister chromatid separation (GO:0010965)3.18611855
90regulation of mitotic sister chromatid segregation (GO:0033047)3.18611855
91negative regulation of mitotic sister chromatid separation (GO:2000816)3.18009360
92negative regulation of mitotic sister chromatid segregation (GO:0033048)3.18009360
93negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.18009360
94negative regulation of sister chromatid segregation (GO:0033046)3.18009360
95spindle assembly checkpoint (GO:0071173)3.16433924
96gastrulation with mouth forming second (GO:0001702)3.16377388
97negative regulation of chromosome segregation (GO:0051985)3.15930690
98DNA topological change (GO:0006265)3.15123866
99negative regulation of DNA repair (GO:0045738)3.14897812
100chromosome segregation (GO:0007059)3.14271365
101synaptonemal complex organization (GO:0070193)3.13690133
102reciprocal DNA recombination (GO:0035825)3.13320547
103reciprocal meiotic recombination (GO:0007131)3.13320547
104piRNA metabolic process (GO:0034587)3.12027148
105pore complex assembly (GO:0046931)3.11501301
106mitotic spindle assembly checkpoint (GO:0007094)3.11294888
107negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.08907453
108protein localization to chromosome (GO:0034502)3.08620633
109regulation of exit from mitosis (GO:0007096)3.07904370
110lung-associated mesenchyme development (GO:0060484)3.07311619
111DNA-dependent DNA replication (GO:0006261)3.06937201
112cytoplasmic mRNA processing body assembly (GO:0033962)3.05495477
113protein complex localization (GO:0031503)3.04852794
114cellular protein complex localization (GO:0034629)3.04601566
115mitotic nuclear envelope disassembly (GO:0007077)3.03173083
116regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.03153675
117regulation of mitotic spindle checkpoint (GO:1903504)3.03153675
118regulation of centrosome duplication (GO:0010824)3.00992136
119microtubule polymerization or depolymerization (GO:0031109)3.00735601
120regulation of establishment of cell polarity (GO:2000114)3.00559207
121sister chromatid cohesion (GO:0007062)2.99935194
122GMP metabolic process (GO:0046037)2.98358106
123DNA duplex unwinding (GO:0032508)2.98146145
124DNA geometric change (GO:0032392)2.97235095
125regulation of meiosis I (GO:0060631)2.96487889
126regulation of nucleobase-containing compound transport (GO:0032239)2.96402745
127N-terminal protein amino acid acetylation (GO:0006474)2.95834707
128regulation of centrosome cycle (GO:0046605)2.89032122
129trophectodermal cell differentiation (GO:0001829)2.87707059
130establishment of integrated proviral latency (GO:0075713)2.86904007
131DNA ligation (GO:0006266)2.85378416
132regulation of helicase activity (GO:0051095)2.82959558
133intestinal epithelial cell development (GO:0060576)2.82447345
134regulation of histone H3-K9 methylation (GO:0051570)2.74760950
135dorsal/ventral axis specification (GO:0009950)2.73413322
136embryonic camera-type eye morphogenesis (GO:0048596)2.73387748
137mRNA stabilization (GO:0048255)2.72920328
138RNA stabilization (GO:0043489)2.72920328
139NLS-bearing protein import into nucleus (GO:0006607)2.71867250
140negative regulation of histone methylation (GO:0031061)2.66526724
141nuclear envelope organization (GO:0006998)2.66152391
142embryonic process involved in female pregnancy (GO:0060136)2.62294026
143regulation of transforming growth factor beta2 production (GO:0032909)2.61257867
144DNA conformation change (GO:0071103)2.58185946
145genitalia morphogenesis (GO:0035112)2.57952848
146positive regulation of cell cycle checkpoint (GO:1901978)2.56776059
147morphogenesis of an epithelial sheet (GO:0002011)2.56081390
148negative regulation of keratinocyte proliferation (GO:0010839)2.54927733
149chromosome condensation (GO:0030261)2.54728085
150mitotic cytokinesis (GO:0000281)2.54368017
151midgut development (GO:0007494)2.52729187
152ATP-dependent chromatin remodeling (GO:0043044)2.50255821
153histone-serine phosphorylation (GO:0035404)2.50167427
154positive regulation of catenin import into nucleus (GO:0035413)2.47439943
155notochord development (GO:0030903)2.47270581
156gap junction assembly (GO:0016264)2.46490451
157positive regulation of glycoprotein biosynthetic process (GO:0010560)2.46132186

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.71802883
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.93927755
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.01057405
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.83192463
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.52727784
6MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.33593555
7CREB1_15753290_ChIP-ChIP_HEK293T_Human3.24054427
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.23790668
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.87013998
10GABP_17652178_ChIP-ChIP_JURKAT_Human2.84474630
11JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.78994679
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.76125231
13KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.72941200
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.64144962
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.44964185
16AR_21909140_ChIP-Seq_LNCAP_Human2.41118874
17VDR_23849224_ChIP-Seq_CD4+_Human2.38765633
18BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.38037555
19TP63_19390658_ChIP-ChIP_HaCaT_Human2.34228265
20PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.28864322
21FLI1_27457419_Chip-Seq_LIVER_Mouse2.28685380
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.19911529
23MYC_18555785_ChIP-Seq_MESCs_Mouse2.13371317
24ELK1_19687146_ChIP-ChIP_HELA_Human2.10266876
25MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.05441632
26CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.04694224
27FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.03554892
28HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.02038884
29WT1_19549856_ChIP-ChIP_CCG9911_Human2.01602224
30* KAP1_22055183_ChIP-Seq_ESCs_Mouse2.00655647
31MYC_19030024_ChIP-ChIP_MESCs_Mouse1.98146757
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.96145895
33FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.95728595
34NELFA_20434984_ChIP-Seq_ESCs_Mouse1.92610625
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.91955977
36YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.90048539
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.84604673
38E2F1_21310950_ChIP-Seq_MCF-7_Human1.82104348
39SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.81894755
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.81676803
41TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.81057011
42ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.79412196
43EGR1_19374776_ChIP-ChIP_THP-1_Human1.77004080
44PADI4_21655091_ChIP-ChIP_MCF-7_Human1.68375911
45MYCN_18555785_ChIP-Seq_MESCs_Mouse1.67507322
46NANOG_18555785_ChIP-Seq_MESCs_Mouse1.66472710
47MYC_18358816_ChIP-ChIP_MESCs_Mouse1.65701974
48SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.63727386
49FOXP3_21729870_ChIP-Seq_TREG_Human1.62144697
50MYC_19079543_ChIP-ChIP_MESCs_Mouse1.59453145
51POU5F1_16153702_ChIP-ChIP_HESCs_Human1.58786731
52POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.58474476
53SALL4_18804426_ChIP-ChIP_XEN_Mouse1.56302908
54SRF_21415370_ChIP-Seq_HL-1_Mouse1.56051795
55GATA1_22025678_ChIP-Seq_K562_Human1.55587235
56HOXB4_20404135_ChIP-ChIP_EML_Mouse1.55345281
57FOXM1_26456572_ChIP-Seq_MCF-7_Human1.53016737
58KDM5A_27292631_Chip-Seq_BREAST_Human1.49837516
59GABP_19822575_ChIP-Seq_HepG2_Human1.49383106
60AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.43106379
61TAF15_26573619_Chip-Seq_HEK293_Human1.42835144
62NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.42161547
63IGF1R_20145208_ChIP-Seq_DFB_Human1.36401584
64ZNF217_24962896_ChIP-Seq_MCF-7_Human1.36186339
65CDX2_19796622_ChIP-Seq_MESCs_Mouse1.35979020
66TCF4_18268006_ChIP-ChIP_LS174T_Human1.33820616
67FOXO3_23340844_ChIP-Seq_DLD1_Human1.33772105
68HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.32095207
69MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.31236403
70TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.30299153
71* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.30092312
72KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.29837228
73KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.29837228
74KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.29837228
75POU3F2_20337985_ChIP-ChIP_501MEL_Human1.29104144
76FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.28658605
77* XRN2_22483619_ChIP-Seq_HELA_Human1.27326336
78DCP1A_22483619_ChIP-Seq_HELA_Human1.26916237
79THAP11_20581084_ChIP-Seq_MESCs_Mouse1.25539775
80FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.24958962
81YY1_21170310_ChIP-Seq_MESCs_Mouse1.24601202
82NOTCH1_21737748_ChIP-Seq_TLL_Human1.24502156
83* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.24386566
84RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.21382231
85OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20531717
86PIAS1_25552417_ChIP-Seq_VCAP_Human1.19397457
87FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.18862808
88ELF1_17652178_ChIP-ChIP_JURKAT_Human1.17913773
89CHD1_26751641_Chip-Seq_LNCaP_Human1.16908164
90PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.16697963
91* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.15153997
92NFE2_27457419_Chip-Seq_LIVER_Mouse1.15135723
93P300_19829295_ChIP-Seq_ESCs_Human1.15021132
94SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13885588
95STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.13808728
96NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.13006211
97SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12046668
98SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11857168
99TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.09961083
100TCF3_18692474_ChIP-Seq_MESCs_Mouse1.07970425
101SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.07708692
102PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.07328715
103FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.06659957
104EWS_26573619_Chip-Seq_HEK293_Human1.04870349
105SOX2_16153702_ChIP-ChIP_HESCs_Human1.04211081
106TTF2_22483619_ChIP-Seq_HELA_Human1.03999387
107ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.03751373
108CDX2_20551321_ChIP-Seq_CACO-2_Human1.03541932
109CLOCK_20551151_ChIP-Seq_293T_Human1.02407538
110TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.01400412
111FUS_26573619_Chip-Seq_HEK293_Human1.01255130
112TCF3_18692474_ChIP-Seq_MEFs_Mouse1.00166935
113SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.98512119
114EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.98457763
115FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.97853534
116SOX2_27498859_Chip-Seq_STOMACH_Mouse0.97339021
117FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.97023903
118POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.96654109
119ELK1_22589737_ChIP-Seq_MCF10A_Human0.96215510
120NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.95725033
121SMAD_19615063_ChIP-ChIP_OVARY_Human0.95064289
122ZFP57_27257070_Chip-Seq_ESCs_Mouse0.94826512
123YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93569625
124CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.93468164
125SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.92601165
126TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.91816089
127TBX3_20139965_ChIP-Seq_ESCs_Mouse0.91137487
128TBX3_20139965_ChIP-Seq_MESCs_Mouse0.90881480
129SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.90602608
130ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.89905757
131POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.88995627
132SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.88435367
133ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.88331019
134POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88271538
135SMAD3_21741376_ChIP-Seq_EPCs_Human0.87999326
136NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.87023241
137GATA6_25053715_ChIP-Seq_YYC3_Human0.86570992
138SOX9_26525672_Chip-Seq_HEART_Mouse0.86149158
139SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.85944510
140SMAD4_21799915_ChIP-Seq_A2780_Human0.85456616
141TOP2B_26459242_ChIP-Seq_MCF-7_Human0.85302637
142HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.84875561
143IRF1_19129219_ChIP-ChIP_H3396_Human0.83146444
144CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.82488975
145E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.80013796
146CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.78276492
147NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.77834955
148NANOG_21062744_ChIP-ChIP_HESCs_Human0.77674368
149CIITA_25753668_ChIP-Seq_RAJI_Human0.77446471
150EZH2_27294783_Chip-Seq_NPCs_Mouse0.76782008
151NANOG_16153702_ChIP-ChIP_HESCs_Human0.76650908
152KLF4_18555785_ChIP-Seq_MESCs_Mouse0.76380276
153EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.75218956
154PCGF2_27294783_Chip-Seq_NPCs_Mouse0.74327071
155STAT3_18555785_Chip-Seq_ESCs_Mouse0.74168989
156NANOG_18555785_Chip-Seq_ESCs_Mouse0.73440015
157SOX17_20123909_ChIP-Seq_XEN_Mouse0.72286457
158NMYC_18555785_Chip-Seq_ESCs_Mouse0.71235057
159IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.70592655
160FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.69952648
161* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.68743230
162EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.68314841

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.74389139
2MP0008057_abnormal_DNA_replication3.80982054
3MP0010352_gastrointestinal_tract_polyps3.74229984
4MP0010234_abnormal_vibrissa_follicle3.68921432
5MP0003111_abnormal_nucleus_morphology3.67387331
6MP0010094_abnormal_chromosome_stability3.64042217
7MP0003718_maternal_effect3.53462381
8MP0006292_abnormal_olfactory_placode3.49189911
9MP0008877_abnormal_DNA_methylation3.25252653
10MP0008007_abnormal_cellular_replicative3.16165606
11MP0003077_abnormal_cell_cycle3.11846329
12MP0003123_paternal_imprinting3.09629958
13MP0008058_abnormal_DNA_repair3.03702693
14MP0004957_abnormal_blastocyst_morpholog2.90366780
15MP0003786_premature_aging2.78165926
16MP0009697_abnormal_copulation2.57712569
17MP0008260_abnormal_autophagy2.55328742
18MP0002009_preneoplasia2.39665356
19MP0000537_abnormal_urethra_morphology2.06536248
20MP0008932_abnormal_embryonic_tissue1.96528052
21MP0003941_abnormal_skin_development1.91979341
22MP0002210_abnormal_sex_determination1.88769645
23MP0003878_abnormal_ear_physiology1.86555123
24MP0005377_hearing/vestibular/ear_phenot1.86555123
25MP0002396_abnormal_hematopoietic_system1.82005665
26MP0008995_early_reproductive_senescence1.81853245
27MP0010307_abnormal_tumor_latency1.81086829
28MP0009672_abnormal_birth_weight1.73661208
29MP0002697_abnormal_eye_size1.71684650
30MP0003315_abnormal_perineum_morphology1.69149866
31MP0001929_abnormal_gametogenesis1.66743678
32MP0002160_abnormal_reproductive_system1.66347737
33MP0003121_genomic_imprinting1.63962584
34MP0010678_abnormal_skin_adnexa1.63208964
35MP0002163_abnormal_gland_morphology1.59155053
36MP0004197_abnormal_fetal_growth/weight/1.57052346
37MP0005248_abnormal_Harderian_gland1.50721714
38MP0001730_embryonic_growth_arrest1.50502783
39MP0001119_abnormal_female_reproductive1.49421756
40MP0005380_embryogenesis_phenotype1.48609058
41MP0001672_abnormal_embryogenesis/_devel1.48609058
42MP0005408_hypopigmentation1.46065693
43MP0000350_abnormal_cell_proliferation1.45539266
44MP0005389_reproductive_system_phenotype1.44970353
45MP0002139_abnormal_hepatobiliary_system1.44728277
46MP0001145_abnormal_male_reproductive1.44552198
47MP0000653_abnormal_sex_gland1.43065226
48MP0003787_abnormal_imprinting1.41397896
49MP0003868_abnormal_feces_composition1.40563260
50MP0000428_abnormal_craniofacial_morphol1.36866126
51MP0004808_abnormal_hematopoietic_stem1.35455185
52MP0002233_abnormal_nose_morphology1.34271329
53MP0001346_abnormal_lacrimal_gland1.34117052
54MP0002277_abnormal_respiratory_mucosa1.30269569
55MP0001188_hyperpigmentation1.27594644
56MP0003385_abnormal_body_wall1.26629873
57MP0003935_abnormal_craniofacial_develop1.26068681
58MP0002092_abnormal_eye_morphology1.24704514
59MP0005076_abnormal_cell_differentiation1.24635424
60MP0003984_embryonic_growth_retardation1.24179781
61MP0001919_abnormal_reproductive_system1.23490272
62MP0004782_abnormal_surfactant_physiolog1.22047807
63MP0005397_hematopoietic_system_phenotyp1.19628898
64MP0001545_abnormal_hematopoietic_system1.19628898
65MP0002876_abnormal_thyroid_physiology1.18568367
66MP0002796_impaired_skin_barrier1.18512369
67MP0002088_abnormal_embryonic_growth/wei1.18450470
68MP0003119_abnormal_digestive_system1.18249739
69MP0005395_other_phenotype1.17533662
70MP0001542_abnormal_bone_strength1.15003969
71MP0003890_abnormal_embryonic-extraembry1.14753329
72MP0005187_abnormal_penis_morphology1.13920917
73MP0000566_synostosis1.13354363
74MP0005171_absent_coat_pigmentation1.13274339
75MP0002132_abnormal_respiratory_system1.13239768
76MP0003698_abnormal_male_reproductive1.13114721
77MP0001666_abnormal_nutrient_absorption1.11579481
78MP0001293_anophthalmia1.10990080
79MP0003937_abnormal_limbs/digits/tail_de1.10818332
80MP0004185_abnormal_adipocyte_glucose1.08467452
81MP0000015_abnormal_ear_pigmentation1.07226372
82MP0008789_abnormal_olfactory_epithelium1.07000401
83MP0000432_abnormal_head_morphology1.06624627
84MP0003938_abnormal_ear_development1.05689716
85MP0001697_abnormal_embryo_size1.04845810
86MP0002111_abnormal_tail_morphology1.03774936
87MP0003221_abnormal_cardiomyocyte_apopto1.03055239
88MP0000383_abnormal_hair_follicle1.01596747
89MP0003699_abnormal_female_reproductive1.00080056
90MP0005085_abnormal_gallbladder_physiolo0.97336343
91MP0002938_white_spotting0.95559096
92MP0003943_abnormal_hepatobiliary_system0.91598442
93MP0010030_abnormal_orbit_morphology0.91384693
94MP0000377_abnormal_hair_follicle0.90960289
95MP0001299_abnormal_eye_distance/0.90237224
96MP0003861_abnormal_nervous_system0.89914633
97MP0005451_abnormal_body_composition0.89056919
98MP0002098_abnormal_vibrissa_morphology0.88996651
99MP0002085_abnormal_embryonic_tissue0.88775253
100MP0002161_abnormal_fertility/fecundity0.87631630
101MP0005409_darkened_coat_color0.87182243
102MP0005501_abnormal_skin_physiology0.86957947
103MP0002080_prenatal_lethality0.86000853
104MP0000477_abnormal_intestine_morphology0.85699736
105MP0000516_abnormal_urinary_system0.84753308
106MP0005367_renal/urinary_system_phenotyp0.84753308
107MP0003936_abnormal_reproductive_system0.84547122
108MP0003755_abnormal_palate_morphology0.84388138
109MP0001529_abnormal_vocalization0.84382909
110MP0000490_abnormal_crypts_of0.83553586
111MP0000462_abnormal_digestive_system0.83537945
112MP0001286_abnormal_eye_development0.82885181
113MP0003115_abnormal_respiratory_system0.82172265
114MP0000627_abnormal_mammary_gland0.81830073
115MP0003705_abnormal_hypodermis_morpholog0.80919990
116MP0002086_abnormal_extraembryonic_tissu0.80871465
117MP0004264_abnormal_extraembryonic_tissu0.80416333
118MP0003567_abnormal_fetal_cardiomyocyte0.79929207
119MP0000313_abnormal_cell_death0.78392561
120MP0002006_tumorigenesis0.78363000
121MP0002102_abnormal_ear_morphology0.76061339
122MP0000647_abnormal_sebaceous_gland0.75370607
123MP0002095_abnormal_skin_pigmentation0.74506158
124MP0002081_perinatal_lethality0.72221643
125MP0005310_abnormal_salivary_gland0.71960814
126MP0002925_abnormal_cardiovascular_devel0.71733429
127MP0002877_abnormal_melanocyte_morpholog0.71063153
128MP0004272_abnormal_basement_membrane0.71019592
129MP0004147_increased_porphyrin_level0.70832956
130MP0009333_abnormal_splenocyte_physiolog0.70225722
131MP0002751_abnormal_autonomic_nervous0.69855903
132MP0003879_abnormal_hair_cell0.69026393
133MP0000762_abnormal_tongue_morphology0.68229988
134MP0003942_abnormal_urinary_system0.67511840
135MP0003091_abnormal_cell_migration0.67054703
136MP0003136_yellow_coat_color0.66948703
137MP0001177_atelectasis0.65731841
138MP0000372_irregular_coat_pigmentation0.65662251
139MP0005647_abnormal_sex_gland0.65084801
140MP0005379_endocrine/exocrine_gland_phen0.64891327
141MP0010630_abnormal_cardiac_muscle0.64803127
142MP0009053_abnormal_anal_canal0.64526118
143MP0002019_abnormal_tumor_incidence0.64402067
144MP0000569_abnormal_digit_pigmentation0.63974808
145MP0002084_abnormal_developmental_patter0.63764355
146MP0006054_spinal_hemorrhage0.63406464
147MP0001915_intracranial_hemorrhage0.63394775
148MP0005621_abnormal_cell_physiology0.63299094
149MP0005394_taste/olfaction_phenotype0.62605974
150MP0005499_abnormal_olfactory_system0.62605974
151MP0005508_abnormal_skeleton_morphology0.62566913
152MP0009703_decreased_birth_body0.62381144

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.35786149
2Impulsivity (HP:0100710)4.83254758
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.77245763
4Chromsome breakage (HP:0040012)4.48898236
5Breast hypoplasia (HP:0003187)4.37368100
6Abnormality of the labia minora (HP:0012880)4.01509993
7Patellar aplasia (HP:0006443)3.78745240
8Meckel diverticulum (HP:0002245)3.67091091
9Aplasia/Hypoplasia of the patella (HP:0006498)3.58155587
10Abnormality of the preputium (HP:0100587)3.50989399
11Abnormality of the ileum (HP:0001549)3.40230505
12Prostate neoplasm (HP:0100787)3.38698240
13Pancreatic fibrosis (HP:0100732)3.31675666
14Curly hair (HP:0002212)3.30400578
15Aplasia/Hypoplasia of the uvula (HP:0010293)3.29116861
16Abnormality of chromosome stability (HP:0003220)3.23918600
17Abnormal spermatogenesis (HP:0008669)3.21756128
18Capillary hemangiomas (HP:0005306)3.14944970
19Volvulus (HP:0002580)3.09015151
20Biliary tract neoplasm (HP:0100574)3.02546541
21Azoospermia (HP:0000027)3.00562819
22Rhabdomyosarcoma (HP:0002859)2.96294611
23Oligodactyly (hands) (HP:0001180)2.88115948
24Right ventricular cardiomyopathy (HP:0011663)2.85872861
25Duodenal stenosis (HP:0100867)2.80205061
26Small intestinal stenosis (HP:0012848)2.80205061
27Hepatoblastoma (HP:0002884)2.77263978
28Medulloblastoma (HP:0002885)2.76720898
29Carpal bone hypoplasia (HP:0001498)2.66769528
30Abnormality of the distal phalanx of the thumb (HP:0009617)2.66222318
31Malignant gastrointestinal tract tumors (HP:0006749)2.62729846
32Gastrointestinal carcinoma (HP:0002672)2.62729846
33Neoplasm of the small intestine (HP:0100833)2.61951296
34Abnormal biliary tract morphology (HP:0012440)2.60027626
35Abnormal hair whorl (HP:0010721)2.56666712
36Large earlobe (HP:0009748)2.54634702
37Papillary thyroid carcinoma (HP:0002895)2.54414761
38Irregular epiphyses (HP:0010582)2.51677968
39Facial hemangioma (HP:0000329)2.50689906
40Ectopic kidney (HP:0000086)2.50604860
41Oligodactyly (HP:0012165)2.49835763
42Clubbing of toes (HP:0100760)2.47436895
43Entropion (HP:0000621)2.45964378
44Asymmetry of the thorax (HP:0001555)2.44530468
45Pancreatic cysts (HP:0001737)2.42068143
46Hyperactive renin-angiotensin system (HP:0000841)2.41818787
47Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.41321130
48Type 2 muscle fiber atrophy (HP:0003554)2.39495113
49Nephroblastoma (Wilms tumor) (HP:0002667)2.38960379
50Hyperglycinemia (HP:0002154)2.38442823
51Degeneration of anterior horn cells (HP:0002398)2.36722743
52Abnormality of the anterior horn cell (HP:0006802)2.36722743
53Deep philtrum (HP:0002002)2.35564600
54Adrenal hypoplasia (HP:0000835)2.31789821
55Rough bone trabeculation (HP:0100670)2.31768205
56Uterine neoplasm (HP:0010784)2.30944696
57Breast aplasia (HP:0100783)2.30709162
58Bone marrow hypocellularity (HP:0005528)2.29801918
59Flat capital femoral epiphysis (HP:0003370)2.29761523
60Myelodysplasia (HP:0002863)2.29583330
61Abnormal lung lobation (HP:0002101)2.29418783
62Cerebral hypomyelination (HP:0006808)2.29075333
63Embryonal renal neoplasm (HP:0011794)2.27300600
64Aplasia/Hypoplasia of the sternum (HP:0006714)2.26414343
65Ureteral duplication (HP:0000073)2.25597519
66Transitional cell carcinoma of the bladder (HP:0006740)2.24489402
67Shawl scrotum (HP:0000049)2.21491793
68True hermaphroditism (HP:0010459)2.20728711
69Hypoplasia of the capital femoral epiphysis (HP:0003090)2.19775110
70Short middle phalanx of the 5th finger (HP:0004220)2.19142541
71Sloping forehead (HP:0000340)2.18244101
72Increased nuchal translucency (HP:0010880)2.15955846
73Abnormality of male internal genitalia (HP:0000022)2.15270383
74Cortical dysplasia (HP:0002539)2.15045712
75Aplasia/Hypoplasia of the breasts (HP:0010311)2.13811049
76Abnormality of the duodenum (HP:0002246)2.12615393
77Absent radius (HP:0003974)2.09280315
78Uterine leiomyosarcoma (HP:0002891)2.08220329
79Leiomyosarcoma (HP:0100243)2.08220329
80Supernumerary spleens (HP:0009799)2.07828218
81Neoplasm of striated muscle (HP:0009728)2.05484526
82Anal stenosis (HP:0002025)2.05184294
83Germ cell neoplasia (HP:0100728)2.03626567
84Abnormality of the fingertips (HP:0001211)2.03572615
85Stillbirth (HP:0003826)2.03469456
86Embryonal neoplasm (HP:0002898)2.03107343
87Bladder neoplasm (HP:0009725)2.02625732
88Bladder carcinoma (HP:0002862)2.02625732
89Absent forearm bone (HP:0003953)2.01705055
90Aplasia involving forearm bones (HP:0009822)2.01705055
91Facial cleft (HP:0002006)2.01310881
92Cystic hygroma (HP:0000476)2.00916341
93Acute myeloid leukemia (HP:0004808)2.00542484
94Flat acetabular roof (HP:0003180)1.99853215
95Short middle phalanx of finger (HP:0005819)1.99055110
96Ovarian neoplasm (HP:0100615)1.98389022
97Short thumb (HP:0009778)1.97847206
98Neoplasm of the thyroid gland (HP:0100031)1.97154913
99Neoplasm of the colon (HP:0100273)1.96753453
100Sandal gap (HP:0001852)1.96590095
101Abnormal trabecular bone morphology (HP:0100671)1.95155710
102Abnormal foot bone ossification (HP:0010675)1.95078569
103Submucous cleft hard palate (HP:0000176)1.94691260
104Areflexia of lower limbs (HP:0002522)1.94661904
105Poor coordination (HP:0002370)1.94201325
106Colon cancer (HP:0003003)1.94173944
107Acanthocytosis (HP:0001927)1.94082359
108Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.93812735
109Deviation of the thumb (HP:0009603)1.91806735
110Heterotopia (HP:0002282)1.91335760
111Neoplasm of the rectum (HP:0100743)1.90644536
112Long clavicles (HP:0000890)1.89849847
113Abnormality of incisor morphology (HP:0011063)1.89832161
114Vertebral arch anomaly (HP:0008438)1.89607980
115High anterior hairline (HP:0009890)1.88875019
116Proximal tubulopathy (HP:0000114)1.88584814
117Overlapping toe (HP:0001845)1.87536756
118Muscle fiber atrophy (HP:0100295)1.86630848
119Abnormality of the phalanges of the hallux (HP:0010057)1.85410832
120Secondary amenorrhea (HP:0000869)1.85118323
121Absent epiphyses (HP:0010577)1.83406793
122Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.83406793
123Abnormal tarsal ossification (HP:0008369)1.83346992
124Aqueductal stenosis (HP:0002410)1.80065090
125Abnormality of the carotid arteries (HP:0005344)1.79875265
126Hypoplastic iliac wings (HP:0002866)1.78897573
127Thyroid carcinoma (HP:0002890)1.78666994
128Intrahepatic cholestasis (HP:0001406)1.78030393
129Midline defect of the nose (HP:0004122)1.77606584
130Cleft eyelid (HP:0000625)1.77178296
131Neonatal short-limb short stature (HP:0008921)1.76001816
132Abnormality of the femoral head (HP:0003368)1.74040126
133Abnormality of the musculature of the pelvis (HP:0001469)1.73079864
134Abnormality of the hip-girdle musculature (HP:0001445)1.73079864
135Proximal placement of thumb (HP:0009623)1.72485489
136Absent eyebrow (HP:0002223)1.71684990
137Abnormality of the epiphysis of the femoral head (HP:0010574)1.71591933
138Hyperglycinuria (HP:0003108)1.70012715
139Breast carcinoma (HP:0003002)1.69197738
140Shoulder girdle muscle weakness (HP:0003547)1.68972029
141Tetraparesis (HP:0002273)1.68878579
142Termporal pattern (HP:0011008)1.68647148
143Insidious onset (HP:0003587)1.68647148
144Vertebral clefting (HP:0008428)1.67951965
145Cafe-au-lait spot (HP:0000957)1.67220675
146Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.64570640
147Aplasia/Hypoplasia of the earlobes (HP:0009906)1.62936188
148Spinal cord lesions (HP:0100561)1.62114449
149Syringomyelia (HP:0003396)1.62114449
150Abnormality of the aortic arch (HP:0012303)1.61563319
151Abnormality of chromosome segregation (HP:0002916)1.61227567
152Neoplasm of the adrenal cortex (HP:0100641)1.60632039
153Short nail (HP:0001799)1.60267075
154Neonatal hypoglycemia (HP:0001998)1.60193981
155Septate vagina (HP:0001153)1.60174743
156Sparse lateral eyebrow (HP:0005338)1.59607066
157Abnormality of the clitoris (HP:0000056)1.59131217
158Obsessive-compulsive behavior (HP:0000722)1.58756914
159Stomach cancer (HP:0012126)1.58602048
160Aplasia/Hypoplasia involving the musculature (HP:0001460)1.58510764
161Missing ribs (HP:0000921)1.58479903
162Tongue fasciculations (HP:0001308)1.58431226
163Astrocytoma (HP:0009592)1.58260125
164Abnormality of the astrocytes (HP:0100707)1.58260125
165Natal tooth (HP:0000695)1.57972835
166Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.57205810
167Neoplasm of the oral cavity (HP:0100649)1.56511667
168Spastic diplegia (HP:0001264)1.56509355
169Relative macrocephaly (HP:0004482)1.55677639
170Cutaneous syndactyly (HP:0012725)1.55126147
171Abnormality of the septum pellucidum (HP:0007375)1.53780320
172Ependymoma (HP:0002888)1.53311366
173Visceral angiomatosis (HP:0100761)1.53174967
174Glioma (HP:0009733)1.52351302
175Ankyloglossia (HP:0010296)1.52251307
176Metabolic alkalosis (HP:0200114)1.51201873
177Cubitus valgus (HP:0002967)1.50088575
178Hemangiomatosis (HP:0007461)1.49752515

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BRSK24.74616443
2AKT33.90594383
3BUB13.74429996
4WEE13.46985638
5MAP3K103.24147705
6MKNK22.94169449
7SRPK12.73408214
8PLK42.65298468
9BRSK12.59702254
10PLK32.43094457
11TNIK2.40042722
12MKNK12.39120199
13EIF2AK12.28669577
14ZAK2.19058580
15STK38L2.15514899
16CASK2.03606461
17CCNB12.01849571
18NEK21.99411603
19TSSK61.89789761
20NUAK11.87412819
21PLK11.78507937
22NLK1.78088826
23ACVR1B1.75288297
24STK31.65485088
25PIK3CA1.61854032
26TAF11.56902187
27FRK1.56548856
28ERBB31.52495012
29PNCK1.51769319
30STK241.51201653
31FGFR21.50666760
32EIF2AK31.50517662
33STK161.49650839
34NEK11.47120449
35PBK1.43774447
36IRAK31.43668176
37CDK31.42172120
38LATS11.41899630
39CDC71.41000454
40MST1R1.40942805
41NEK61.40881608
42VRK11.36613564
43CDK61.35062814
44STK391.34457133
45CHEK21.31497626
46FGFR11.30663781
47SGK21.27684151
48SIK31.26411480
49EEF2K1.21589649
50TTK1.17181592
51EIF2AK21.15574310
52AURKB1.11890373
53MAP3K41.11758767
54SCYL21.10873449
55PDK31.08061534
56PDK41.08061534
57CDK71.06760498
58MAP3K21.04603350
59TRIM281.03080101
60BMPR21.02956341
61DYRK31.02574975
62MARK31.02055446
63FGFR31.00105031
64PLK20.98800507
65RPS6KA40.98742190
66RPS6KB20.98123196
67PDGFRA0.98026291
68MET0.97739342
69PDK20.94730664
70LATS20.93149378
71ATR0.90687188
72BCR0.88262321
73MUSK0.87936786
74BRAF0.87379184
75CDK80.87065297
76CAMK1G0.86682091
77KSR10.84758786
78CHEK10.83737509
79CHUK0.81342696
80PINK10.81325883
81PASK0.80303402
82STK40.73878404
83IRAK20.72420666
84IRAK40.69386423
85CAMKK20.68123950
86PIM10.67944655
87SGK30.64279654
88MST40.62814948
89PRPF4B0.60865686
90BMPR1B0.60550295
91RIPK10.60261170
92ATM0.59478123
93AURKA0.58808697
94YES10.56920117
95SGK4940.55456700
96SGK2230.55456700
97NEK90.54108865
98PRKAA10.53161752
99OXSR10.52576284
100ICK0.52374260
101EPHA40.51970035
102CDK20.51894097
103DYRK20.51589412
104IKBKB0.49263011
105CDK10.48636883
106PRKCI0.48316664
107CAMK1D0.46982498
108CSNK1E0.45660201
109CSNK2A10.45641676
110WNK30.45178281
111CDK40.43110090
112MAP3K140.42714010
113NME20.42013636
114PDGFRB0.41311842
115CSNK1G10.40328110
116OBSCN0.39937384
117RPS6KA50.38925124
118ALK0.38039601
119CDK120.37304265
120MTOR0.36866060
121DMPK0.36814061
122WNK10.36231635
123PIM20.35890856
124RET0.34388302
125EPHA20.34258152
126TYRO30.34120071
127RPS6KB10.32923798
128CSNK1A10.27902673
129CLK10.27537043
130ERBB40.25674292
131TXK0.24938941
132CSNK2A20.24585336
133MAPK130.22637213
134MAP3K80.22362519
135BRD40.21799999
136MAP3K30.20817611
137MELK0.20035227
138ADRBK20.17803504
139TEC0.16658437
140DYRK1A0.16427848

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.48192431
2RNA polymerase_Homo sapiens_hsa030204.84749187
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.52576912
4Basal transcription factors_Homo sapiens_hsa030223.45995392
5RNA transport_Homo sapiens_hsa030133.26365294
6Cell cycle_Homo sapiens_hsa041103.20818675
7Homologous recombination_Homo sapiens_hsa034402.98367302
8Fanconi anemia pathway_Homo sapiens_hsa034602.92534998
9Spliceosome_Homo sapiens_hsa030402.42591741
10Mismatch repair_Homo sapiens_hsa034302.40029599
11Proteasome_Homo sapiens_hsa030502.35929947
12Pyrimidine metabolism_Homo sapiens_hsa002402.35798857
13Adherens junction_Homo sapiens_hsa045202.29586637
14DNA replication_Homo sapiens_hsa030302.25791271
15Nucleotide excision repair_Homo sapiens_hsa034202.10857722
16Regulation of autophagy_Homo sapiens_hsa041402.03097882
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.98257170
18RNA degradation_Homo sapiens_hsa030181.95097954
19p53 signaling pathway_Homo sapiens_hsa041151.88358088
20mRNA surveillance pathway_Homo sapiens_hsa030151.87333926
21Base excision repair_Homo sapiens_hsa034101.86610716
22Purine metabolism_Homo sapiens_hsa002301.85196336
23Endometrial cancer_Homo sapiens_hsa052131.68972619
24Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.54967039
25Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.52440056
26Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.50437323
27Colorectal cancer_Homo sapiens_hsa052101.42385820
28Tight junction_Homo sapiens_hsa045301.36954570
29Epstein-Barr virus infection_Homo sapiens_hsa051691.36782422
30Oocyte meiosis_Homo sapiens_hsa041141.36619409
31Caffeine metabolism_Homo sapiens_hsa002321.33617855
32Non-homologous end-joining_Homo sapiens_hsa034501.33330664
33Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.32530651
34Arginine biosynthesis_Homo sapiens_hsa002201.29621822
35Propanoate metabolism_Homo sapiens_hsa006401.28199403
36Pentose and glucuronate interconversions_Homo sapiens_hsa000401.24855779
37Vitamin digestion and absorption_Homo sapiens_hsa049771.24608683
38Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.24394635
39Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.20270074
40Circadian rhythm_Homo sapiens_hsa047101.12343643
41Wnt signaling pathway_Homo sapiens_hsa043101.11714377
42Basal cell carcinoma_Homo sapiens_hsa052171.11612384
43Chronic myeloid leukemia_Homo sapiens_hsa052201.11456143
44Lysine degradation_Homo sapiens_hsa003101.09457633
45Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.08600670
46Herpes simplex infection_Homo sapiens_hsa051681.06030706
47Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.01769913
48Steroid biosynthesis_Homo sapiens_hsa001000.98485427
49Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.97579802
50Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.91471694
51Intestinal immune network for IgA production_Homo sapiens_hsa046720.89219701
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.88687378
53Nitrogen metabolism_Homo sapiens_hsa009100.88654713
54Renal cell carcinoma_Homo sapiens_hsa052110.87539507
55Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.87251568
56Retinol metabolism_Homo sapiens_hsa008300.82897714
57Folate biosynthesis_Homo sapiens_hsa007900.82758739
58Proteoglycans in cancer_Homo sapiens_hsa052050.81976588
59Fatty acid degradation_Homo sapiens_hsa000710.79302494
60Glycerophospholipid metabolism_Homo sapiens_hsa005640.78577819
61Influenza A_Homo sapiens_hsa051640.78437924
62Pyruvate metabolism_Homo sapiens_hsa006200.78431751
63Pancreatic cancer_Homo sapiens_hsa052120.78211312
64Starch and sucrose metabolism_Homo sapiens_hsa005000.77633574
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.77035176
66Pentose phosphate pathway_Homo sapiens_hsa000300.76948663
67Drug metabolism - other enzymes_Homo sapiens_hsa009830.76040996
68Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.73940509
69Fat digestion and absorption_Homo sapiens_hsa049750.73491448
70Arachidonic acid metabolism_Homo sapiens_hsa005900.71799204
71ErbB signaling pathway_Homo sapiens_hsa040120.71700517
72Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71283879
73Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.70523530
74Viral carcinogenesis_Homo sapiens_hsa052030.69886408
75Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.68995153
76TGF-beta signaling pathway_Homo sapiens_hsa043500.67489315
77Glioma_Homo sapiens_hsa052140.67371674
78Non-small cell lung cancer_Homo sapiens_hsa052230.66379292
79Dorso-ventral axis formation_Homo sapiens_hsa043200.65337878
80FoxO signaling pathway_Homo sapiens_hsa040680.65103962
81mTOR signaling pathway_Homo sapiens_hsa041500.64782453
82Allograft rejection_Homo sapiens_hsa053300.64573488
83Choline metabolism in cancer_Homo sapiens_hsa052310.64481261
84One carbon pool by folate_Homo sapiens_hsa006700.64451579
85Protein digestion and absorption_Homo sapiens_hsa049740.64146266
86NF-kappa B signaling pathway_Homo sapiens_hsa040640.63934769
87Alcoholism_Homo sapiens_hsa050340.62951337
88Sulfur metabolism_Homo sapiens_hsa009200.62815404
89Selenocompound metabolism_Homo sapiens_hsa004500.62317197
90Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.61933443
91NOD-like receptor signaling pathway_Homo sapiens_hsa046210.60992020
92Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.60046263
93Sphingolipid metabolism_Homo sapiens_hsa006000.59200741
94Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.58164691
95MicroRNAs in cancer_Homo sapiens_hsa052060.56752685
96Steroid hormone biosynthesis_Homo sapiens_hsa001400.56017001
97Cysteine and methionine metabolism_Homo sapiens_hsa002700.55783481
98Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.55404624
99Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.55084519
100Antigen processing and presentation_Homo sapiens_hsa046120.54248451
101SNARE interactions in vesicular transport_Homo sapiens_hsa041300.53796051
102Prolactin signaling pathway_Homo sapiens_hsa049170.53636812
103Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.52856581
104Rheumatoid arthritis_Homo sapiens_hsa053230.52427628
105AMPK signaling pathway_Homo sapiens_hsa041520.51008717
106HTLV-I infection_Homo sapiens_hsa051660.51006012
107Gap junction_Homo sapiens_hsa045400.50295227
1082-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.50248144
109Biosynthesis of amino acids_Homo sapiens_hsa012300.49926223
110Measles_Homo sapiens_hsa051620.49852067
111Fatty acid metabolism_Homo sapiens_hsa012120.48535326
112AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.48305768
113Autoimmune thyroid disease_Homo sapiens_hsa053200.44568887
114Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44198335
115Transcriptional misregulation in cancer_Homo sapiens_hsa052020.43431382
116Phototransduction_Homo sapiens_hsa047440.43079870
117RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.42574054
118Collecting duct acid secretion_Homo sapiens_hsa049660.41512234
119Protein export_Homo sapiens_hsa030600.41207809
120Jak-STAT signaling pathway_Homo sapiens_hsa046300.40005605
121Prostate cancer_Homo sapiens_hsa052150.39237283
122Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38934935
123Type I diabetes mellitus_Homo sapiens_hsa049400.38930117
124Small cell lung cancer_Homo sapiens_hsa052220.38585541
125Thyroid cancer_Homo sapiens_hsa052160.38409575
126Hippo signaling pathway_Homo sapiens_hsa043900.37628249
127Legionellosis_Homo sapiens_hsa051340.36904055
128Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.32470391
129Linoleic acid metabolism_Homo sapiens_hsa005910.27708328
130Mineral absorption_Homo sapiens_hsa049780.25835575
131Graft-versus-host disease_Homo sapiens_hsa053320.25658739
132Systemic lupus erythematosus_Homo sapiens_hsa053220.25638822
133Hepatitis B_Homo sapiens_hsa051610.25343462
134Inositol phosphate metabolism_Homo sapiens_hsa005620.24561791
135Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.23143965
136Metabolic pathways_Homo sapiens_hsa011000.23010887
137Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.21128736
138Longevity regulating pathway - mammal_Homo sapiens_hsa042110.21123527
139Ether lipid metabolism_Homo sapiens_hsa005650.20205783
140Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.19878050
141Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.19752519
142Apoptosis_Homo sapiens_hsa042100.19394187
143Thyroid hormone signaling pathway_Homo sapiens_hsa049190.17946794
144Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.16910641
145Renin-angiotensin system_Homo sapiens_hsa046140.16100304
146Pathways in cancer_Homo sapiens_hsa052000.15061086
147Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.14085098
148Fructose and mannose metabolism_Homo sapiens_hsa000510.14080308
149Shigellosis_Homo sapiens_hsa051310.12989771
150Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.12820057
151Melanoma_Homo sapiens_hsa052180.12651251
152alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.11318330
153Hepatitis C_Homo sapiens_hsa051600.10762727
154Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.10093165
155Glutathione metabolism_Homo sapiens_hsa004800.09471100
156Hedgehog signaling pathway_Homo sapiens_hsa043400.08912137

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