

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of cAMP-mediated signaling (GO:0043951) | 8.29631226 |
| 2 | inner mitochondrial membrane organization (GO:0007007) | 7.21433751 |
| 3 | piRNA metabolic process (GO:0034587) | 6.80276143 |
| 4 | opioid receptor signaling pathway (GO:0038003) | 5.81677197 |
| 5 | behavioral response to ethanol (GO:0048149) | 5.56851799 |
| 6 | cilium or flagellum-dependent cell motility (GO:0001539) | 5.54381002 |
| 7 | ether lipid metabolic process (GO:0046485) | 5.53510180 |
| 8 | sphingosine metabolic process (GO:0006670) | 5.47028411 |
| 9 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 5.16080049 |
| 10 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 5.09391597 |
| 11 | response to dietary excess (GO:0002021) | 5.00059338 |
| 12 | positive regulation of cAMP-mediated signaling (GO:0043950) | 4.98437143 |
| 13 | sphingoid metabolic process (GO:0046519) | 4.86160414 |
| 14 | diol metabolic process (GO:0034311) | 4.84607436 |
| 15 | adult feeding behavior (GO:0008343) | 4.83271337 |
| 16 | protein insertion into membrane (GO:0051205) | 4.81770020 |
| 17 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 4.57343023 |
| 18 | regulation of acrosome reaction (GO:0060046) | 4.54697834 |
| 19 | thyroid hormone generation (GO:0006590) | 4.47815183 |
| 20 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 4.42767749 |
| 21 | somite development (GO:0061053) | 4.26936874 |
| 22 | nucleotide transmembrane transport (GO:1901679) | 4.23959899 |
| 23 | regulation of protein glycosylation (GO:0060049) | 4.22446980 |
| 24 | dendritic spine morphogenesis (GO:0060997) | 4.09132376 |
| 25 | cellular ketone body metabolic process (GO:0046950) | 4.08659554 |
| 26 | membrane depolarization during action potential (GO:0086010) | 4.04872047 |
| 27 | protein localization to synapse (GO:0035418) | 4.01065196 |
| 28 | thyroid hormone metabolic process (GO:0042403) | 3.94003341 |
| 29 | regulation of DNA endoreduplication (GO:0032875) | 3.86946118 |
| 30 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.83883960 |
| 31 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.83883960 |
| 32 | cornea development in camera-type eye (GO:0061303) | 3.81642778 |
| 33 | ribonucleoprotein complex disassembly (GO:0032988) | 3.76327752 |
| 34 | regulation of translational termination (GO:0006449) | 3.74993112 |
| 35 | mRNA cleavage (GO:0006379) | 3.71893239 |
| 36 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.64847442 |
| 37 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.64444436 |
| 38 | regulation of cAMP-mediated signaling (GO:0043949) | 3.64033412 |
| 39 | prepulse inhibition (GO:0060134) | 3.63143448 |
| 40 | ketone body metabolic process (GO:1902224) | 3.61635866 |
| 41 | viral mRNA export from host cell nucleus (GO:0046784) | 3.50615763 |
| 42 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.44270104 |
| 43 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.41377547 |
| 44 | spinal cord development (GO:0021510) | 3.35430046 |
| 45 | glycerol ether metabolic process (GO:0006662) | 3.34510707 |
| 46 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.30929800 |
| 47 | phenol-containing compound catabolic process (GO:0019336) | 3.25012437 |
| 48 | synaptic transmission, glutamatergic (GO:0035249) | 3.17116284 |
| 49 | ether metabolic process (GO:0018904) | 3.14361054 |
| 50 | cell-cell junction maintenance (GO:0045217) | 3.11567814 |
| 51 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.10724440 |
| 52 | regulation of female receptivity (GO:0045924) | 3.06328505 |
| 53 | lateral sprouting from an epithelium (GO:0060601) | 3.04602624 |
| 54 | arginine catabolic process (GO:0006527) | 3.04590693 |
| 55 | sequestering of actin monomers (GO:0042989) | 3.02148359 |
| 56 | CDP-diacylglycerol metabolic process (GO:0046341) | 2.99738556 |
| 57 | neuronal action potential (GO:0019228) | 2.94124603 |
| 58 | glutathione biosynthetic process (GO:0006750) | 2.93228560 |
| 59 | intraciliary transport (GO:0042073) | 2.92976529 |
| 60 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 2.91974221 |
| 61 | negative regulation of heart growth (GO:0061117) | 2.91974221 |
| 62 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.91750535 |
| 63 | vitamin catabolic process (GO:0009111) | 2.88502673 |
| 64 | fat-soluble vitamin catabolic process (GO:0042363) | 2.88502673 |
| 65 | female mating behavior (GO:0060180) | 2.86743923 |
| 66 | calcium ion import (GO:0070509) | 2.86355310 |
| 67 | negative regulation of telomerase activity (GO:0051974) | 2.85800609 |
| 68 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.85748946 |
| 69 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.83398819 |
| 70 | resolution of meiotic recombination intermediates (GO:0000712) | 2.81710082 |
| 71 | positive regulation of protein complex disassembly (GO:0043243) | 2.81257714 |
| 72 | cranial nerve morphogenesis (GO:0021602) | 2.80483690 |
| 73 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.79538499 |
| 74 | axoneme assembly (GO:0035082) | 2.78690700 |
| 75 | cellular response to ammonium ion (GO:0071242) | 2.78516257 |
| 76 | retinal ganglion cell axon guidance (GO:0031290) | 2.74242440 |
| 77 | DNA methylation involved in gamete generation (GO:0043046) | 2.73089794 |
| 78 | behavioral response to nicotine (GO:0035095) | 2.71794079 |
| 79 | cellular response to electrical stimulus (GO:0071257) | 2.71549758 |
| 80 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.68992297 |
| 81 | urogenital system development (GO:0001655) | 2.68798758 |
| 82 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.68395519 |
| 83 | ATP synthesis coupled proton transport (GO:0015986) | 2.68395519 |
| 84 | nonribosomal peptide biosynthetic process (GO:0019184) | 2.67517512 |
| 85 | axonemal dynein complex assembly (GO:0070286) | 2.66084338 |
| 86 | negative regulation of heart rate (GO:0010459) | 2.61162079 |
| 87 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 2.60120835 |
| 88 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.60068072 |
| 89 | coenzyme catabolic process (GO:0009109) | 2.59770233 |
| 90 | smooth muscle tissue development (GO:0048745) | 2.57561112 |
| 91 | cardiovascular system development (GO:0072358) | 2.56088382 |
| 92 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.55177288 |
| 93 | lens fiber cell differentiation (GO:0070306) | 2.54688633 |
| 94 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 2.54010447 |
| 95 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 2.53622230 |
| 96 | notochord development (GO:0030903) | 2.52909891 |
| 97 | protein import into peroxisome matrix (GO:0016558) | 2.52113561 |
| 98 | transmission of nerve impulse (GO:0019226) | 2.51547366 |
| 99 | cell junction maintenance (GO:0034331) | 2.51267644 |
| 100 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 10.5873401 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 6.47210505 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.71711335 |
| 3 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.57546430 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.41979565 |
| 5 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.94727253 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.81021558 |
| 7 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.75903296 |
| 8 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.65313158 |
| 9 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.49525088 |
| 10 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.25152911 |
| 11 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.15404925 |
| 12 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.01654110 |
| 13 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.96646348 |
| 14 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.93700179 |
| 15 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.91986993 |
| 16 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.91986993 |
| 17 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.91150095 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.90397792 |
| 19 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.89599704 |
| 20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.88780143 |
| 21 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.85095394 |
| 22 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.75165610 |
| 23 | P300_19829295_ChIP-Seq_ESCs_Human | 1.71291946 |
| 24 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.68900962 |
| 25 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.66443699 |
| 26 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.64210669 |
| 27 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.60378848 |
| 28 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.59474748 |
| 29 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.59400904 |
| 30 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.58175882 |
| 31 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.57631766 |
| 32 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.56210739 |
| 33 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.55753438 |
| 34 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.52452391 |
| 35 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.51420395 |
| 36 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.51420395 |
| 37 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.51200017 |
| 38 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.51200017 |
| 39 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.49029214 |
| 40 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.44660914 |
| 41 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.44559353 |
| 42 | STAT3_23295773_ChIP-Seq_U87_Human | 1.44257077 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.41920679 |
| 44 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.40648839 |
| 45 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.39646066 |
| 46 | FUS_26573619_Chip-Seq_HEK293_Human | 1.39358948 |
| 47 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.35861099 |
| 48 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.31722343 |
| 49 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.31108511 |
| 50 | TCF4_23295773_ChIP-Seq_U87_Human | 1.30203204 |
| 51 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.28002767 |
| 52 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26435553 |
| 53 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.24788807 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.20230405 |
| 55 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.20230405 |
| 56 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.19555394 |
| 57 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.17218902 |
| 58 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.17142485 |
| 59 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.14896167 |
| 60 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.14559251 |
| 61 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.14198578 |
| 62 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.14178936 |
| 63 | EWS_26573619_Chip-Seq_HEK293_Human | 1.12702199 |
| 64 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.12492676 |
| 65 | AR_25329375_ChIP-Seq_VCAP_Human | 1.11727268 |
| 66 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.11497280 |
| 67 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.11073662 |
| 68 | RXR_22108803_ChIP-Seq_LS180_Human | 1.11011789 |
| 69 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.10888205 |
| 70 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.09639935 |
| 71 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.09138585 |
| 72 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.08761307 |
| 73 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.08521621 |
| 74 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.08286280 |
| 75 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.07388348 |
| 76 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.06621793 |
| 77 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.05178433 |
| 78 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.05162401 |
| 79 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.03576909 |
| 80 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.01684811 |
| 81 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.01668845 |
| 82 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.01658502 |
| 83 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.01306244 |
| 84 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.01186700 |
| 85 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.99840894 |
| 86 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.99176489 |
| 87 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.98065641 |
| 88 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.97160188 |
| 89 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.95619667 |
| 90 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.95589508 |
| 91 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.94455387 |
| 92 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.92858994 |
| 93 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.91881183 |
| 94 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.91644156 |
| 95 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.90876945 |
| 96 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.90001015 |
| 97 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.88118519 |
| 98 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.87984152 |
| 99 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.87930242 |
| 100 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.87641831 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 6.81888692 |
| 2 | MP0002837_dystrophic_cardiac_calcinosis | 5.01076025 |
| 3 | MP0002876_abnormal_thyroid_physiology | 3.86329872 |
| 4 | MP0005360_urolithiasis | 3.83057020 |
| 5 | MP0005167_abnormal_blood-brain_barrier | 2.99301877 |
| 6 | MP0002102_abnormal_ear_morphology | 2.91251989 |
| 7 | MP0008877_abnormal_DNA_methylation | 2.85313187 |
| 8 | MP0009780_abnormal_chondrocyte_physiolo | 2.82510367 |
| 9 | MP0006292_abnormal_olfactory_placode | 2.78835034 |
| 10 | MP0004147_increased_porphyrin_level | 2.50520810 |
| 11 | MP0003122_maternal_imprinting | 2.39177235 |
| 12 | MP0000537_abnormal_urethra_morphology | 2.37808194 |
| 13 | MP0005646_abnormal_pituitary_gland | 2.23508329 |
| 14 | MP0005551_abnormal_eye_electrophysiolog | 2.22342368 |
| 15 | MP0004742_abnormal_vestibular_system | 2.18209017 |
| 16 | MP0009278_abnormal_bone_marrow | 2.16556598 |
| 17 | MP0003121_genomic_imprinting | 2.13089278 |
| 18 | MP0001968_abnormal_touch/_nociception | 2.07414505 |
| 19 | MP0003787_abnormal_imprinting | 1.93872481 |
| 20 | MP0002733_abnormal_thermal_nociception | 1.90663833 |
| 21 | MP0005410_abnormal_fertilization | 1.86197638 |
| 22 | MP0002277_abnormal_respiratory_mucosa | 1.82835760 |
| 23 | MP0001545_abnormal_hematopoietic_system | 1.78679213 |
| 24 | MP0005397_hematopoietic_system_phenotyp | 1.78679213 |
| 25 | MP0009764_decreased_sensitivity_to | 1.66600267 |
| 26 | MP0000778_abnormal_nervous_system | 1.65898268 |
| 27 | MP0009046_muscle_twitch | 1.61936136 |
| 28 | MP0004145_abnormal_muscle_electrophysio | 1.61889888 |
| 29 | MP0008775_abnormal_heart_ventricle | 1.59606493 |
| 30 | MP0002272_abnormal_nervous_system | 1.53290833 |
| 31 | MP0004142_abnormal_muscle_tone | 1.50888677 |
| 32 | MP0005645_abnormal_hypothalamus_physiol | 1.48674686 |
| 33 | MP0003195_calcinosis | 1.48291120 |
| 34 | MP0003941_abnormal_skin_development | 1.47230847 |
| 35 | MP0001970_abnormal_pain_threshold | 1.44415783 |
| 36 | MP0004130_abnormal_muscle_cell | 1.43624547 |
| 37 | MP0004859_abnormal_synaptic_plasticity | 1.42271486 |
| 38 | MP0003880_abnormal_central_pattern | 1.36552155 |
| 39 | MP0006072_abnormal_retinal_apoptosis | 1.36191393 |
| 40 | MP0005499_abnormal_olfactory_system | 1.27397230 |
| 41 | MP0005394_taste/olfaction_phenotype | 1.27397230 |
| 42 | MP0006035_abnormal_mitochondrial_morpho | 1.27028437 |
| 43 | MP0009053_abnormal_anal_canal | 1.23611142 |
| 44 | MP0009745_abnormal_behavioral_response | 1.20432092 |
| 45 | MP0001485_abnormal_pinna_reflex | 1.20241213 |
| 46 | MP0005503_abnormal_tendon_morphology | 1.16257633 |
| 47 | MP0000681_abnormal_thyroid_gland | 1.15787382 |
| 48 | MP0003950_abnormal_plasma_membrane | 1.13323365 |
| 49 | MP0003633_abnormal_nervous_system | 1.10528684 |
| 50 | MP0004185_abnormal_adipocyte_glucose | 1.09239279 |
| 51 | MP0006054_spinal_hemorrhage | 1.08022760 |
| 52 | MP0008789_abnormal_olfactory_epithelium | 1.06964268 |
| 53 | MP0003938_abnormal_ear_development | 1.04352429 |
| 54 | MP0005253_abnormal_eye_physiology | 1.03550535 |
| 55 | MP0000049_abnormal_middle_ear | 1.02581986 |
| 56 | MP0005195_abnormal_posterior_eye | 1.02431783 |
| 57 | MP0001853_heart_inflammation | 1.00925979 |
| 58 | MP0000678_abnormal_parathyroid_gland | 1.00763535 |
| 59 | MP0008875_abnormal_xenobiotic_pharmacok | 1.00638452 |
| 60 | MP0002572_abnormal_emotion/affect_behav | 1.00133596 |
| 61 | MP0002229_neurodegeneration | 1.00095613 |
| 62 | MP0001188_hyperpigmentation | 0.98736739 |
| 63 | MP0009765_abnormal_xenobiotic_induced | 0.96977460 |
| 64 | MP0003635_abnormal_synaptic_transmissio | 0.92530921 |
| 65 | MP0001664_abnormal_digestion | 0.92178045 |
| 66 | MP0000955_abnormal_spinal_cord | 0.91017083 |
| 67 | MP0002557_abnormal_social/conspecific_i | 0.90592126 |
| 68 | MP0005310_abnormal_salivary_gland | 0.89469595 |
| 69 | MP0003567_abnormal_fetal_cardiomyocyte | 0.85186553 |
| 70 | MP0005389_reproductive_system_phenotype | 0.84437353 |
| 71 | MP0008872_abnormal_physiological_respon | 0.83694878 |
| 72 | MP0002693_abnormal_pancreas_physiology | 0.83624829 |
| 73 | MP0002067_abnormal_sensory_capabilities | 0.83123384 |
| 74 | MP0002095_abnormal_skin_pigmentation | 0.82988587 |
| 75 | MP0002752_abnormal_somatic_nervous | 0.82368501 |
| 76 | MP0002653_abnormal_ependyma_morphology | 0.80888709 |
| 77 | MP0001919_abnormal_reproductive_system | 0.77878964 |
| 78 | MP0002249_abnormal_larynx_morphology | 0.77014388 |
| 79 | MP0002063_abnormal_learning/memory/cond | 0.76217451 |
| 80 | MP0004043_abnormal_pH_regulation | 0.75555351 |
| 81 | MP0000569_abnormal_digit_pigmentation | 0.75372163 |
| 82 | MP0003638_abnormal_response/metabolism_ | 0.74905161 |
| 83 | MP0001486_abnormal_startle_reflex | 0.71508936 |
| 84 | MP0003698_abnormal_male_reproductive | 0.71395067 |
| 85 | MP0004858_abnormal_nervous_system | 0.71391765 |
| 86 | MP0000647_abnormal_sebaceous_gland | 0.70329927 |
| 87 | MP0002882_abnormal_neuron_morphology | 0.68241508 |
| 88 | MP0003959_abnormal_lean_body | 0.67374231 |
| 89 | MP0001929_abnormal_gametogenesis | 0.65953113 |
| 90 | MP0003315_abnormal_perineum_morphology | 0.65480234 |
| 91 | MP0000230_abnormal_systemic_arterial | 0.64552739 |
| 92 | MP0006276_abnormal_autonomic_nervous | 0.63184675 |
| 93 | MP0002734_abnormal_mechanical_nocicepti | 0.62700278 |
| 94 | MP0003937_abnormal_limbs/digits/tail_de | 0.61262510 |
| 95 | MP0003045_fibrosis | 0.58988580 |
| 96 | MP0001944_abnormal_pancreas_morphology | 0.58963657 |
| 97 | MP0003631_nervous_system_phenotype | 0.57548928 |
| 98 | MP0003693_abnormal_embryo_hatching | 0.56858423 |
| 99 | MP0003690_abnormal_glial_cell | 0.56257987 |
| 100 | MP0005266_abnormal_metabolism | 0.55951506 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Thyroid-stimulating hormone excess (HP:0002925) | 9.24568486 |
| 2 | Volvulus (HP:0002580) | 7.09812559 |
| 3 | Agitation (HP:0000713) | 4.98897470 |
| 4 | Myokymia (HP:0002411) | 4.37454322 |
| 5 | Amblyopia (HP:0000646) | 3.92526249 |
| 6 | Abnormality of the nasal septum (HP:0000419) | 3.84162431 |
| 7 | Intestinal atresia (HP:0011100) | 3.74530457 |
| 8 | Genetic anticipation (HP:0003743) | 3.67188414 |
| 9 | Pancreatic islet-cell hyperplasia (HP:0004510) | 3.49989264 |
| 10 | Lissencephaly (HP:0001339) | 3.31340096 |
| 11 | Decreased central vision (HP:0007663) | 3.07995590 |
| 12 | Gaze-evoked nystagmus (HP:0000640) | 3.06328353 |
| 13 | Abnormality of the aortic arch (HP:0012303) | 3.03050306 |
| 14 | Tented upper lip vermilion (HP:0010804) | 2.94807900 |
| 15 | Poor speech (HP:0002465) | 2.92048176 |
| 16 | Congenital stationary night blindness (HP:0007642) | 2.87769586 |
| 17 | Pendular nystagmus (HP:0012043) | 2.85908701 |
| 18 | Impulsivity (HP:0100710) | 2.82526143 |
| 19 | Restlessness (HP:0000711) | 2.81989071 |
| 20 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.75287237 |
| 21 | Hypoplasia of the brainstem (HP:0002365) | 2.75287237 |
| 22 | Ketoacidosis (HP:0001993) | 2.72076436 |
| 23 | Broad-based gait (HP:0002136) | 2.70647605 |
| 24 | Malignant hyperthermia (HP:0002047) | 2.67429812 |
| 25 | Oligodontia (HP:0000677) | 2.62445754 |
| 26 | Poor head control (HP:0002421) | 2.57573314 |
| 27 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.54492637 |
| 28 | Methylmalonic aciduria (HP:0012120) | 2.51818481 |
| 29 | Anhidrosis (HP:0000970) | 2.49618743 |
| 30 | Microretrognathia (HP:0000308) | 2.49434832 |
| 31 | Medial flaring of the eyebrow (HP:0010747) | 2.45960043 |
| 32 | Tubular atrophy (HP:0000092) | 2.45818016 |
| 33 | Keratoconus (HP:0000563) | 2.43609601 |
| 34 | Increased corneal curvature (HP:0100692) | 2.43609601 |
| 35 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.42910221 |
| 36 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.42807781 |
| 37 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.40429852 |
| 38 | Mesangial abnormality (HP:0001966) | 2.33401889 |
| 39 | Abnormality of the ileum (HP:0001549) | 2.26375921 |
| 40 | Tetany (HP:0001281) | 2.23231316 |
| 41 | Spastic tetraparesis (HP:0001285) | 2.21805219 |
| 42 | Hypomagnesemia (HP:0002917) | 2.20564612 |
| 43 | Median cleft lip (HP:0000161) | 2.19038515 |
| 44 | Acute necrotizing encephalopathy (HP:0006965) | 2.18433367 |
| 45 | Hypoproteinemia (HP:0003075) | 2.18293519 |
| 46 | Chromsome breakage (HP:0040012) | 2.15480086 |
| 47 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.14885642 |
| 48 | Absent/shortened dynein arms (HP:0200106) | 2.14885642 |
| 49 | True hermaphroditism (HP:0010459) | 2.14870101 |
| 50 | Abnormality of the corticospinal tract (HP:0002492) | 2.12446644 |
| 51 | Optic nerve hypoplasia (HP:0000609) | 2.12260871 |
| 52 | Submucous cleft hard palate (HP:0000176) | 2.11153079 |
| 53 | Type II lissencephaly (HP:0007260) | 2.11136209 |
| 54 | Abnormality of alanine metabolism (HP:0010916) | 2.10612751 |
| 55 | Hyperalaninemia (HP:0003348) | 2.10612751 |
| 56 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.10612751 |
| 57 | Small hand (HP:0200055) | 2.09643417 |
| 58 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.08002880 |
| 59 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.07282472 |
| 60 | Abnormality of midbrain morphology (HP:0002418) | 2.07165875 |
| 61 | Molar tooth sign on MRI (HP:0002419) | 2.07165875 |
| 62 | Large for gestational age (HP:0001520) | 2.06693184 |
| 63 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.06428257 |
| 64 | Long nose (HP:0003189) | 2.04587877 |
| 65 | Esotropia (HP:0000565) | 2.04582469 |
| 66 | Chronic sinusitis (HP:0011109) | 2.02733398 |
| 67 | Pigmentary retinal degeneration (HP:0001146) | 2.01272311 |
| 68 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.98020878 |
| 69 | Myotonia (HP:0002486) | 1.96280334 |
| 70 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.94447487 |
| 71 | Duplicated collecting system (HP:0000081) | 1.94031376 |
| 72 | Focal motor seizures (HP:0011153) | 1.93121915 |
| 73 | Focal seizures (HP:0007359) | 1.92778995 |
| 74 | Broad alveolar ridges (HP:0000187) | 1.90110842 |
| 75 | Methylmalonic acidemia (HP:0002912) | 1.89642678 |
| 76 | Rhinitis (HP:0012384) | 1.87982286 |
| 77 | Hyperpituitarism (HP:0010514) | 1.86879817 |
| 78 | Abnormality of the renal collecting system (HP:0004742) | 1.86597928 |
| 79 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.86516849 |
| 80 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.86516849 |
| 81 | Progressive cerebellar ataxia (HP:0002073) | 1.86292561 |
| 82 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.84242463 |
| 83 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.82195749 |
| 84 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.82195749 |
| 85 | Progressive macrocephaly (HP:0004481) | 1.82080730 |
| 86 | Hyperglycinuria (HP:0003108) | 1.78984212 |
| 87 | Cerebellar dysplasia (HP:0007033) | 1.78772482 |
| 88 | Optic disc pallor (HP:0000543) | 1.78586864 |
| 89 | Short 1st metacarpal (HP:0010034) | 1.78097709 |
| 90 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.78097709 |
| 91 | Attenuation of retinal blood vessels (HP:0007843) | 1.77422566 |
| 92 | Acute encephalopathy (HP:0006846) | 1.75210002 |
| 93 | Pancreatic cysts (HP:0001737) | 1.74432048 |
| 94 | Cone-rod dystrophy (HP:0000548) | 1.74056382 |
| 95 | Abnormality of the labia minora (HP:0012880) | 1.73572899 |
| 96 | Abnormality of the lower motor neuron (HP:0002366) | 1.72955804 |
| 97 | Abnormal number of incisors (HP:0011064) | 1.72887696 |
| 98 | Chronic bronchitis (HP:0004469) | 1.72217932 |
| 99 | Gastrointestinal atresia (HP:0002589) | 1.71984361 |
| 100 | Pancreatic fibrosis (HP:0100732) | 1.71847922 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 6.72546494 |
| 2 | ADRBK2 | 5.88297223 |
| 3 | FRK | 4.36232572 |
| 4 | EPHB2 | 3.43578641 |
| 5 | TAOK3 | 2.58744357 |
| 6 | KSR1 | 2.53491207 |
| 7 | PINK1 | 2.50092706 |
| 8 | MAPK13 | 2.10357160 |
| 9 | ZAK | 2.08996887 |
| 10 | MAP4K1 | 1.95199005 |
| 11 | RIPK4 | 1.93997483 |
| 12 | TNK2 | 1.79364695 |
| 13 | MAP4K2 | 1.74257091 |
| 14 | IRAK1 | 1.72197999 |
| 15 | MARK1 | 1.53455162 |
| 16 | NUAK1 | 1.47621613 |
| 17 | MAP2K7 | 1.46203832 |
| 18 | DYRK3 | 1.45571387 |
| 19 | GRK1 | 1.45058502 |
| 20 | PLK2 | 1.39047858 |
| 21 | MAP3K11 | 1.38352184 |
| 22 | BMPR1B | 1.34605991 |
| 23 | ADRBK1 | 1.32422089 |
| 24 | STK24 | 1.31892532 |
| 25 | PRKCG | 1.24322648 |
| 26 | RPS6KA4 | 1.24241926 |
| 27 | WNK3 | 1.17542273 |
| 28 | MAP3K9 | 1.13056850 |
| 29 | PRKCE | 1.01538078 |
| 30 | PNCK | 1.01324359 |
| 31 | IRAK3 | 1.00089719 |
| 32 | ERBB2 | 0.94132744 |
| 33 | TYRO3 | 0.86338883 |
| 34 | CSNK1G2 | 0.83715954 |
| 35 | CAMKK2 | 0.82375127 |
| 36 | CSNK1G3 | 0.80911171 |
| 37 | ERN1 | 0.80508969 |
| 38 | PAK3 | 0.80491041 |
| 39 | TRIM28 | 0.78849329 |
| 40 | NTRK2 | 0.77243083 |
| 41 | TGFBR1 | 0.75177975 |
| 42 | WNK4 | 0.72620196 |
| 43 | DYRK1A | 0.72542569 |
| 44 | INSRR | 0.71378696 |
| 45 | CSNK1G1 | 0.68119014 |
| 46 | CAMK2A | 0.67107481 |
| 47 | CAMKK1 | 0.65061561 |
| 48 | MKNK1 | 0.63936409 |
| 49 | CASK | 0.63441381 |
| 50 | TAF1 | 0.63171047 |
| 51 | TIE1 | 0.62873239 |
| 52 | CSNK1A1L | 0.62516924 |
| 53 | EPHA4 | 0.62321869 |
| 54 | FYN | 0.61716896 |
| 55 | PKN1 | 0.60237252 |
| 56 | PRKCI | 0.59613058 |
| 57 | BCR | 0.59480795 |
| 58 | VRK1 | 0.58014269 |
| 59 | KIT | 0.55818067 |
| 60 | FES | 0.55534335 |
| 61 | MAPKAPK5 | 0.54823344 |
| 62 | CAMK1 | 0.54622416 |
| 63 | SGK1 | 0.54504704 |
| 64 | CSNK1A1 | 0.54168019 |
| 65 | MAP3K4 | 0.51538545 |
| 66 | IRAK2 | 0.50857115 |
| 67 | PHKG1 | 0.49873141 |
| 68 | PHKG2 | 0.49873141 |
| 69 | TXK | 0.49602451 |
| 70 | PRKACA | 0.47131189 |
| 71 | ERBB3 | 0.46097202 |
| 72 | CSF1R | 0.43940947 |
| 73 | STK3 | 0.43457598 |
| 74 | ATM | 0.43082976 |
| 75 | MINK1 | 0.41513740 |
| 76 | TEC | 0.40314057 |
| 77 | MAP2K4 | 0.38748215 |
| 78 | PRKCA | 0.38234761 |
| 79 | DYRK2 | 0.37799996 |
| 80 | CSNK1E | 0.37571771 |
| 81 | ACVR1B | 0.37396410 |
| 82 | MAP2K6 | 0.35586968 |
| 83 | PIK3CA | 0.35461683 |
| 84 | GRK7 | 0.35061481 |
| 85 | CAMK1G | 0.34869027 |
| 86 | MAPK3 | 0.34607980 |
| 87 | MAPK10 | 0.32530730 |
| 88 | CSNK2A2 | 0.32431190 |
| 89 | IRAK4 | 0.32272963 |
| 90 | RPS6KA3 | 0.31442716 |
| 91 | ATR | 0.30847515 |
| 92 | PLK3 | 0.30004360 |
| 93 | STK11 | 0.29470662 |
| 94 | NTRK3 | 0.29323927 |
| 95 | RPS6KA5 | 0.29271257 |
| 96 | PRKG1 | 0.28319562 |
| 97 | PRKACG | 0.28059360 |
| 98 | OBSCN | 0.27924356 |
| 99 | DAPK2 | 0.27490503 |
| 100 | GRK5 | 0.27469433 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Sulfur relay system_Homo sapiens_hsa04122 | 3.90158985 |
| 2 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.48399123 |
| 3 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.99236462 |
| 4 | Nicotine addiction_Homo sapiens_hsa05033 | 2.81978509 |
| 5 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.79496015 |
| 6 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.74529718 |
| 7 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.30528995 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.29081127 |
| 9 | Phototransduction_Homo sapiens_hsa04744 | 2.24493127 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.18502298 |
| 11 | Morphine addiction_Homo sapiens_hsa05032 | 2.12840798 |
| 12 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.07723474 |
| 13 | Insulin secretion_Homo sapiens_hsa04911 | 1.96719742 |
| 14 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.88280250 |
| 15 | Olfactory transduction_Homo sapiens_hsa04740 | 1.80226678 |
| 16 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.72060208 |
| 17 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.71072564 |
| 18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.70307043 |
| 19 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.66643868 |
| 20 | Mineral absorption_Homo sapiens_hsa04978 | 1.60641961 |
| 21 | Taste transduction_Homo sapiens_hsa04742 | 1.57755126 |
| 22 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.55699178 |
| 23 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.51361758 |
| 24 | Huntingtons disease_Homo sapiens_hsa05016 | 1.50276349 |
| 25 | Asthma_Homo sapiens_hsa05310 | 1.49568515 |
| 26 | Alzheimers disease_Homo sapiens_hsa05010 | 1.45439656 |
| 27 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.44360707 |
| 28 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.40617230 |
| 29 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.37653123 |
| 30 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.37611803 |
| 31 | Basal transcription factors_Homo sapiens_hsa03022 | 1.34835659 |
| 32 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.28510409 |
| 33 | ABC transporters_Homo sapiens_hsa02010 | 1.23474709 |
| 34 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.23161716 |
| 35 | GABAergic synapse_Homo sapiens_hsa04727 | 1.13251316 |
| 36 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.08493419 |
| 37 | RNA degradation_Homo sapiens_hsa03018 | 1.08275772 |
| 38 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.02809702 |
| 39 | Peroxisome_Homo sapiens_hsa04146 | 0.98104942 |
| 40 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.96691599 |
| 41 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.96457953 |
| 42 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.95915446 |
| 43 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.94367016 |
| 44 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.93463278 |
| 45 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.93408221 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.93048630 |
| 47 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.91626633 |
| 48 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.90731744 |
| 49 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.89379688 |
| 50 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.87374969 |
| 51 | Proteasome_Homo sapiens_hsa03050 | 0.84902900 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.83852249 |
| 53 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.83593185 |
| 54 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.83476818 |
| 55 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.80281515 |
| 56 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.78447423 |
| 57 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.78225426 |
| 58 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.77250879 |
| 59 | Allograft rejection_Homo sapiens_hsa05330 | 0.77097404 |
| 60 | Homologous recombination_Homo sapiens_hsa03440 | 0.76374211 |
| 61 | Salivary secretion_Homo sapiens_hsa04970 | 0.76318467 |
| 62 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.76096930 |
| 63 | Circadian entrainment_Homo sapiens_hsa04713 | 0.75798528 |
| 64 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.75656826 |
| 65 | Spliceosome_Homo sapiens_hsa03040 | 0.73930580 |
| 66 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.73871803 |
| 67 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.70522345 |
| 68 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.67688365 |
| 69 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.66905240 |
| 70 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.65744520 |
| 71 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.57758389 |
| 72 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.56352147 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.53946656 |
| 74 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.53626304 |
| 75 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.53432334 |
| 76 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.53220592 |
| 77 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.52927310 |
| 78 | Alcoholism_Homo sapiens_hsa05034 | 0.51118607 |
| 79 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.50873684 |
| 80 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.50813916 |
| 81 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.49502519 |
| 82 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.49199807 |
| 83 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.49061517 |
| 84 | Cocaine addiction_Homo sapiens_hsa05030 | 0.48202187 |
| 85 | Purine metabolism_Homo sapiens_hsa00230 | 0.46630409 |
| 86 | Ribosome_Homo sapiens_hsa03010 | 0.44676933 |
| 87 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.44040960 |
| 88 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.43722245 |
| 89 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.43154527 |
| 90 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.41500667 |
| 91 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.40499491 |
| 92 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.40224583 |
| 93 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.37141800 |
| 94 | Bile secretion_Homo sapiens_hsa04976 | 0.34602585 |
| 95 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.31414725 |
| 96 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.30236310 |
| 97 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.29092046 |
| 98 | Protein export_Homo sapiens_hsa03060 | 0.26565683 |
| 99 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.25416136 |
| 100 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25218070 |

