MIOX

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1drug transport (GO:0015893)8.95902039
2lysine catabolic process (GO:0006554)8.62293723
3lysine metabolic process (GO:0006553)8.62293723
4organic cation transport (GO:0015695)8.55570655
5phosphate ion transport (GO:0006817)8.47410479
6drug catabolic process (GO:0042737)7.20568886
7quaternary ammonium group transport (GO:0015697)7.05650801
8glyoxylate metabolic process (GO:0046487)6.93717329
9phosphate ion transmembrane transport (GO:0035435)6.85278710
10exogenous drug catabolic process (GO:0042738)6.83700272
11response to mercury ion (GO:0046689)6.81352843
12cysteine metabolic process (GO:0006534)6.52960902
13tricarboxylic acid metabolic process (GO:0072350)6.19712649
14excretion (GO:0007588)6.11564078
15aspartate family amino acid catabolic process (GO:0009068)5.76439365
16nonribosomal peptide biosynthetic process (GO:0019184)5.75287980
17short-chain fatty acid metabolic process (GO:0046459)5.67803718
18renal absorption (GO:0070293)5.50593998
19phosphate ion homeostasis (GO:0055062)5.50437741
20trivalent inorganic anion homeostasis (GO:0072506)5.50437741
21metanephric tubule development (GO:0072170)5.34012571
22metanephric nephron tubule development (GO:0072234)5.34012571
23branched-chain amino acid metabolic process (GO:0009081)5.32872591
24toxin transport (GO:1901998)5.32408120
25vitamin D metabolic process (GO:0042359)5.27054976
26homocysteine metabolic process (GO:0050667)5.24205128
27L-phenylalanine metabolic process (GO:0006558)5.18642124
28erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.18642124
29L-phenylalanine catabolic process (GO:0006559)5.14092476
30erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.14092476
31glutathione biosynthetic process (GO:0006750)5.10884198
32fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.05448247
33amino-acid betaine transport (GO:0015838)5.03357701
34carnitine transport (GO:0015879)5.03357701
35aromatic amino acid family catabolic process (GO:0009074)5.02326690
36valine metabolic process (GO:0006573)4.94238620
37metanephric nephron epithelium development (GO:0072243)4.91713279
38modified amino acid transport (GO:0072337)4.90481854
39glycoside metabolic process (GO:0016137)4.83695841
40proline metabolic process (GO:0006560)4.83520460
41serine family amino acid catabolic process (GO:0009071)4.83106366
42tryptophan catabolic process (GO:0006569)4.80543281
43indole-containing compound catabolic process (GO:0042436)4.80543281
44indolalkylamine catabolic process (GO:0046218)4.80543281
45cellular modified amino acid catabolic process (GO:0042219)4.69861802
46serine family amino acid metabolic process (GO:0009069)4.68516264
47behavioral response to nicotine (GO:0035095)4.60348433
48tryptophan metabolic process (GO:0006568)4.57782448
49amino-acid betaine metabolic process (GO:0006577)4.50788782
502-oxoglutarate metabolic process (GO:0006103)4.50574033
51metanephric epithelium development (GO:0072207)4.49302224
52fructose metabolic process (GO:0006000)4.43478231
53branched-chain amino acid catabolic process (GO:0009083)4.43172669
54fatty acid beta-oxidation (GO:0006635)4.42198508
55cellular ketone body metabolic process (GO:0046950)4.28557938
56response to pheromone (GO:0019236)4.28423102
57acetyl-CoA metabolic process (GO:0006084)4.25028832
58nephron tubule development (GO:0072080)4.21040246
59cardiovascular system development (GO:0072358)4.14578447
60peptide biosynthetic process (GO:0043043)4.10521451
61response to parathyroid hormone (GO:0071107)4.09065963
62carnitine metabolic process (GO:0009437)4.08714541
63fatty acid oxidation (GO:0019395)4.07471990
64lipid oxidation (GO:0034440)3.99550884
65water-soluble vitamin biosynthetic process (GO:0042364)3.90606041
66L-fucose catabolic process (GO:0042355)3.87886275
67fucose catabolic process (GO:0019317)3.87886275
68L-fucose metabolic process (GO:0042354)3.87886275
69response to growth hormone (GO:0060416)3.86495330
70cellular amino acid catabolic process (GO:0009063)3.83722436
71glutamate metabolic process (GO:0006536)3.82441200
72serine family amino acid biosynthetic process (GO:0009070)3.80322920
73NADH metabolic process (GO:0006734)3.78391666
74indole-containing compound metabolic process (GO:0042430)3.74310316
75response to phenylpropanoid (GO:0080184)3.74210957
76alpha-amino acid catabolic process (GO:1901606)3.73634416
77peptide catabolic process (GO:0043171)3.73009529
78renal tubule development (GO:0061326)3.72180742
79aromatic amino acid family metabolic process (GO:0009072)3.71635553
80ketone body metabolic process (GO:1902224)3.68134982
81glutathione metabolic process (GO:0006749)3.67765657
82fatty acid catabolic process (GO:0009062)3.64670752
83vitamin transport (GO:0051180)3.60106635
84epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.58705386
85glutathione derivative metabolic process (GO:1901685)3.58627896
86glutathione derivative biosynthetic process (GO:1901687)3.58627896
87kynurenine metabolic process (GO:0070189)3.57666816
88sodium-independent organic anion transport (GO:0043252)3.56668052
89oligosaccharide catabolic process (GO:0009313)3.55780800
90S-adenosylmethionine metabolic process (GO:0046500)3.53583988
91neural tube formation (GO:0001841)3.53214044
92detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.52530268
93drug metabolic process (GO:0017144)3.50595888
94polyol transport (GO:0015791)3.49705645
95organic acid catabolic process (GO:0016054)3.48233954
96carboxylic acid catabolic process (GO:0046395)3.48233954
97sulfur amino acid catabolic process (GO:0000098)3.47612722
98negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.46281324
99monocarboxylic acid catabolic process (GO:0072329)3.44564828
100sulfur compound transport (GO:0072348)3.44452276
101response to magnesium ion (GO:0032026)3.43085451
102platelet dense granule organization (GO:0060155)3.40682711
103biotin metabolic process (GO:0006768)3.40231970
104protein complex biogenesis (GO:0070271)3.39598640
105nephron epithelium development (GO:0072009)3.38946725
106energy coupled proton transport, down electrochemical gradient (GO:0015985)3.38642560
107ATP synthesis coupled proton transport (GO:0015986)3.38642560
108indolalkylamine metabolic process (GO:0006586)3.38241161
109beta-amyloid metabolic process (GO:0050435)3.36798663
110respiratory chain complex IV assembly (GO:0008535)3.35767683
111dicarboxylic acid metabolic process (GO:0043648)3.35539415
112tricarboxylic acid cycle (GO:0006099)3.34395064
113pyrimidine nucleobase catabolic process (GO:0006208)3.34096118
114response to lead ion (GO:0010288)3.33913059
115L-methionine salvage (GO:0071267)3.32675699
116L-methionine biosynthetic process (GO:0071265)3.32675699
117amino acid salvage (GO:0043102)3.32675699
118protein-cofactor linkage (GO:0018065)3.32161926
119mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.25883645
120mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.25461855
121positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc3.25292303
122nephron tubule morphogenesis (GO:0072078)3.24909997
123DNA deamination (GO:0045006)3.20489047
124regulation of cilium movement (GO:0003352)3.18684970
125mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.15993460
126mitochondrial respiratory chain complex I assembly (GO:0032981)3.15993460
127NADH dehydrogenase complex assembly (GO:0010257)3.15993460
128regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033393.15690083
129mitochondrial respiratory chain complex assembly (GO:0033108)3.09565070
130nephron epithelium morphogenesis (GO:0072088)3.08441204
131cytochrome complex assembly (GO:0017004)3.04454094
132preassembly of GPI anchor in ER membrane (GO:0016254)3.04113048
133piRNA metabolic process (GO:0034587)3.03503833
134collecting duct development (GO:0072044)2.97631643
135ubiquinone biosynthetic process (GO:0006744)2.93954122
136embryonic epithelial tube formation (GO:0001838)2.92181244
137regulation of mesenchymal cell apoptotic process (GO:2001053)2.91363017
138nucleobase catabolic process (GO:0046113)2.90014454
139nephron tubule formation (GO:0072079)2.89652168
140cornea development in camera-type eye (GO:0061303)2.88771714
141epithelial cilium movement (GO:0003351)2.84765191
142somite development (GO:0061053)2.84340110
143nonmotile primary cilium assembly (GO:0035058)2.82855092
144somite rostral/caudal axis specification (GO:0032525)2.81586747
145aldehyde catabolic process (GO:0046185)2.80979189
146electron transport chain (GO:0022900)2.77646485
147negative regulation of telomere maintenance (GO:0032205)2.77502165
148kidney morphogenesis (GO:0060993)2.77236800
149regulation of glucokinase activity (GO:0033131)2.76093357
150regulation of hexokinase activity (GO:1903299)2.76093357
151gamma-aminobutyric acid transport (GO:0015812)2.75874319
152retinal cone cell development (GO:0046549)2.74561921
153establishment of protein localization to mitochondrial membrane (GO:0090151)2.73981463
154activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.73942945
155epithelial tube formation (GO:0072175)2.71261090
156respiratory electron transport chain (GO:0022904)2.70539075
157ubiquinone metabolic process (GO:0006743)2.69952778
158mannosylation (GO:0097502)2.69354691
159axoneme assembly (GO:0035082)2.65757673
160protein polyglutamylation (GO:0018095)2.63669017
161detection of light stimulus involved in sensory perception (GO:0050962)2.60849435
162detection of light stimulus involved in visual perception (GO:0050908)2.60849435
163hydrogen ion transmembrane transport (GO:1902600)2.54973953
164adenosine metabolic process (GO:0046085)2.54383539
165cilium organization (GO:0044782)2.52025519
166proton transport (GO:0015992)2.51781511
167cilium morphogenesis (GO:0060271)2.51278155
168GPI anchor metabolic process (GO:0006505)2.50452541
169transepithelial transport (GO:0070633)2.49189705
170hydrogen transport (GO:0006818)2.48338995
171tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.46351975
172RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.46351975
173tachykinin receptor signaling pathway (GO:0007217)2.46074921
174urogenital system development (GO:0001655)2.45467877
175regulation of microtubule-based movement (GO:0060632)2.44199756
176aminoglycoside antibiotic metabolic process (GO:0030647)11.3309207
177urate metabolic process (GO:0046415)11.0274355
178drug transmembrane transport (GO:0006855)10.5980952

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse6.64417463
2RXR_22158963_ChIP-Seq_LIVER_Mouse5.54561536
3PPARA_22158963_ChIP-Seq_LIVER_Mouse4.58807491
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.20962315
5ZNF274_21170338_ChIP-Seq_K562_Hela4.07046027
6LXR_22158963_ChIP-Seq_LIVER_Mouse3.99849577
7ESR1_21235772_ChIP-Seq_MCF-7_Human3.75295346
8AR_21909140_ChIP-Seq_LNCAP_Human3.02091120
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.92126265
10HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.90414884
11TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.89292170
12ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.83901486
13TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.73471091
14EZH2_22144423_ChIP-Seq_EOC_Human2.61511119
15GBX2_23144817_ChIP-Seq_PC3_Human2.53179456
16CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.47035627
17ZFP57_27257070_Chip-Seq_ESCs_Mouse2.36345726
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.35607312
19IGF1R_20145208_ChIP-Seq_DFB_Human2.33196992
20ESR2_21235772_ChIP-Seq_MCF-7_Human2.21842848
21RARG_19884340_ChIP-ChIP_MEFs_Mouse2.21484131
22POU3F2_20337985_ChIP-ChIP_501MEL_Human2.21159292
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.20620893
24FLI1_27457419_Chip-Seq_LIVER_Mouse2.18920063
25NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.05298113
26EWS_26573619_Chip-Seq_HEK293_Human2.03959868
27GABP_17652178_ChIP-ChIP_JURKAT_Human2.03274225
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.02288021
29EGR1_23403033_ChIP-Seq_LIVER_Mouse2.02077731
30P300_19829295_ChIP-Seq_ESCs_Human2.01602369
31E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.01092844
32CLOCK_20551151_ChIP-Seq_293T_Human2.00445925
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.98655622
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.92796074
35FUS_26573619_Chip-Seq_HEK293_Human1.92525756
36TAF15_26573619_Chip-Seq_HEK293_Human1.87276800
37CDX2_20551321_ChIP-Seq_CACO-2_Human1.83982128
38TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.83757699
39VDR_22108803_ChIP-Seq_LS180_Human1.83693713
40EST1_17652178_ChIP-ChIP_JURKAT_Human1.82480277
41PCGF2_27294783_Chip-Seq_ESCs_Mouse1.81770811
42KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.81556745
43NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.78460838
44SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.73829811
45ER_23166858_ChIP-Seq_MCF-7_Human1.73796987
46TP53_22573176_ChIP-Seq_HFKS_Human1.72651269
47PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.72587487
48FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.70168765
49TRIM28_21343339_ChIP-Seq_HEK293_Human1.70167345
50ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.69681210
51HNF4A_19822575_ChIP-Seq_HepG2_Human1.68464991
52CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.64556375
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.63463386
54SALL1_21062744_ChIP-ChIP_HESCs_Human1.63059221
55EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.62985684
56MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.62083117
57BMI1_23680149_ChIP-Seq_NPCS_Mouse1.61984042
58RBPJ_22232070_ChIP-Seq_NCS_Mouse1.61107905
59ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.56341981
60CBX2_27304074_Chip-Seq_ESCs_Mouse1.53232779
61TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.53017198
62CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.50868682
63PCGF2_27294783_Chip-Seq_NPCs_Mouse1.49599570
64GATA4_25053715_ChIP-Seq_YYC3_Human1.47030211
65SOX2_27498859_Chip-Seq_STOMACH_Mouse1.46855877
66STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.46294189
67BCAT_22108803_ChIP-Seq_LS180_Human1.44156661
68FOXA2_19822575_ChIP-Seq_HepG2_Human1.43970560
69SOX2_19829295_ChIP-Seq_ESCs_Human1.43511919
70NANOG_19829295_ChIP-Seq_ESCs_Human1.43511919
71MYC_18940864_ChIP-ChIP_HL60_Human1.41314768
72FOXA1_27270436_Chip-Seq_PROSTATE_Human1.40801646
73FOXA1_25329375_ChIP-Seq_VCAP_Human1.40801646
74AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.39259049
75UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.38796133
76FOXO3_23340844_ChIP-Seq_DLD1_Human1.37887536
77GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.36839211
78CBP_20019798_ChIP-Seq_JUKART_Human1.36427717
79IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36427717
80ETV2_25802403_ChIP-Seq_MESCs_Mouse1.35262120
81IRF1_19129219_ChIP-ChIP_H3396_Human1.33933256
82FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.32728241
83NOTCH1_21737748_ChIP-Seq_TLL_Human1.32723918
84MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.32548488
85TCF4_22108803_ChIP-Seq_LS180_Human1.32525510
86AR_25329375_ChIP-Seq_VCAP_Human1.32115051
87RNF2_27304074_Chip-Seq_NSC_Mouse1.31728832
88LXR_22292898_ChIP-Seq_THP-1_Human1.30346561
89TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29749312
90POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.29749312
91REST_21632747_ChIP-Seq_MESCs_Mouse1.29287919
92STAT3_1855785_ChIP-Seq_MESCs_Mouse1.27074903
93SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.26945275
94SMAD4_21799915_ChIP-Seq_A2780_Human1.26146890
95STAT3_23295773_ChIP-Seq_U87_Human1.25758827
96GATA6_25053715_ChIP-Seq_YYC3_Human1.24259541
97TCF4_23295773_ChIP-Seq_U87_Human1.22910172
98SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.22734522
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.21174840
100RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20324440
101* RACK7_27058665_Chip-Seq_MCF-7_Human1.19695906
102SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19538867
103GATA3_21878914_ChIP-Seq_MCF-7_Human1.19211907
104TBX20_22328084_ChIP-Seq_HEART_Mouse1.18812182
105TBX20_22080862_ChIP-Seq_HEART_Mouse1.18812182
106AR_20517297_ChIP-Seq_VCAP_Human1.18304844
107NCOR_22424771_ChIP-Seq_293T_Human1.18039564
108NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.17944993
109NFE2_27457419_Chip-Seq_LIVER_Mouse1.17937785
110NR3C1_21868756_ChIP-Seq_MCF10A_Human1.17377462
111PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.16766029
112SMAD3_21741376_ChIP-Seq_EPCs_Human1.14434188
113VDR_23849224_ChIP-Seq_CD4+_Human1.13669767
114SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12980500
115FOXA1_21572438_ChIP-Seq_LNCaP_Human1.12833230
116CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.11892821
117RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.11803573
118SMAD3_21741376_ChIP-Seq_HESCs_Human1.11407555
119KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11404602
120EZH2_27294783_Chip-Seq_NPCs_Mouse1.11276859
121RUNX2_22187159_ChIP-Seq_PCA_Human1.11001907
122EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.10852837
123IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.10301303
124NANOG_18555785_Chip-Seq_ESCs_Mouse1.08888178
125CDX2_22108803_ChIP-Seq_LS180_Human1.08620704
126ELK1_19687146_ChIP-ChIP_HELA_Human1.06455629
127HOXB7_26014856_ChIP-Seq_BT474_Human1.06321047
128NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.05900076
129JARID2_20064375_ChIP-Seq_MESCs_Mouse1.05833990
130TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05022561
131EZH2_27304074_Chip-Seq_ESCs_Mouse1.04712193
132PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.03951782
133P53_22387025_ChIP-Seq_ESCs_Mouse1.03605010
134STAT3_18555785_Chip-Seq_ESCs_Mouse1.03166417
135OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03088342
136POU5F1_16153702_ChIP-ChIP_HESCs_Human1.03012180
137AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.02704687
138EGR1_19032775_ChIP-ChIP_M12_Human1.02698809
139ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.02673126
140HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.02111002
141EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.01888337
142PIAS1_25552417_ChIP-Seq_VCAP_Human1.01514042
143MYC_19829295_ChIP-Seq_ESCs_Human1.01389068
144GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.01324699
145SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.01180879
146PPAR_26484153_Chip-Seq_NCI-H1993_Human0.99518706
147HTT_18923047_ChIP-ChIP_STHdh_Human0.98946765
148PRDM14_20953172_ChIP-Seq_ESCs_Human0.98687438
149SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.98542403
150CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.98222251
151SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.98028577
152FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.97402010
153RXR_22108803_ChIP-Seq_LS180_Human0.95998274
154CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94110268
155KAP1_22055183_ChIP-Seq_ESCs_Mouse0.92404345
156EP300_21415370_ChIP-Seq_HL-1_Mouse0.90649347
157TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.90429065
158RAC3_21632823_ChIP-Seq_H3396_Human0.89031518
159NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.87447008
160RAD21_21589869_ChIP-Seq_MESCs_Mouse0.85636057
161P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.85158288
162SMC4_20622854_ChIP-Seq_HELA_Human0.85156554
163HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.84356491
164NANOG_18692474_ChIP-Seq_MEFs_Mouse0.83453152
165SOX2_20726797_ChIP-Seq_SW620_Human0.83369829
166SMAD4_21741376_ChIP-Seq_HESCs_Human0.80971200
167BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.80060873
168SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.79743488
169CSB_26484114_Chip-Seq_FIBROBLAST_Human0.79560975
170TP63_23658742_ChIP-Seq_EP156T_Human0.78812394
171BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.77741531
172ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.76184412
173GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.76091586
174SALL4_18804426_ChIP-ChIP_XEN_Mouse0.76082691
175SMAD4_21741376_ChIP-Seq_EPCs_Human0.75141530
176SOX11_22085726_ChIP-Seq_ESNs_Mouse0.75021916
177NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.74929495
178FOXH1_21741376_ChIP-Seq_EPCs_Human0.74904738
179ESET_19884257_ChIP-Seq_ESCs_Mouse0.74890009
180EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.74246199
181FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.73447676
182EOMES_21245162_ChIP-Seq_HESCs_Human0.73228274
183STAT1_17558387_ChIP-Seq_HELA_Human0.71816410
184CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.71193124
185CEBPB_22108803_ChIP-Seq_LS180_Human0.71036707
186TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.70990698
187P68_20966046_ChIP-Seq_HELA_Human0.70656741
188TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.70473468
189CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.70059112
190SOX2_18692474_ChIP-Seq_MEFs_Mouse0.69862561
191GATA1_19941827_ChIP-Seq_MEL86_Mouse0.69733614
192KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.68902173
193TAF2_19829295_ChIP-Seq_ESCs_Human0.68783664
194* MYC_19915707_ChIP-ChIP_AK7_Human0.68600461
195ERG_21242973_ChIP-ChIP_JURKAT_Human0.67456569
196SOX2_22085726_ChIP-Seq_NPCs_Mouse0.67416782

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis7.91548449
2MP0004043_abnormal_pH_regulation6.74485396
3MP0005332_abnormal_amino_acid5.02211655
4MP0004019_abnormal_vitamin_homeostasis4.98179136
5MP0002139_abnormal_hepatobiliary_system4.96490651
6MP0003195_calcinosis4.09208620
7MP0001765_abnormal_ion_homeostasis3.98941323
8MP0009643_abnormal_urine_homeostasis3.98661676
9MP0002138_abnormal_hepatobiliary_system3.69507760
10MP0005636_abnormal_mineral_homeostasis3.24157345
11MP0001756_abnormal_urination3.20581882
12MP0002136_abnormal_kidney_physiology2.98747139
13MP0008875_abnormal_xenobiotic_pharmacok2.93810041
14MP0005377_hearing/vestibular/ear_phenot2.75206008
15MP0003878_abnormal_ear_physiology2.75206008
16MP0001958_emphysema2.52123942
17MP0003252_abnormal_bile_duct2.34091300
18MP0008877_abnormal_DNA_methylation2.28230836
19MP0006072_abnormal_retinal_apoptosis2.19184878
20MP0005365_abnormal_bile_salt2.16804330
21MP0005085_abnormal_gallbladder_physiolo2.10755742
22MP0005551_abnormal_eye_electrophysiolog2.03211694
23MP0005058_abnormal_lysosome_morphology2.00271682
24MP0003186_abnormal_redox_activity1.88351782
25MP0005451_abnormal_body_composition1.86507402
26MP0008872_abnormal_physiological_respon1.85641963
27MP0002102_abnormal_ear_morphology1.83637838
28MP0004885_abnormal_endolymph1.77778524
29MP0008961_abnormal_basal_metabolism1.77660415
30MP0000538_abnormal_urinary_bladder1.71164556
31MP0005253_abnormal_eye_physiology1.68731822
32MP0003011_delayed_dark_adaptation1.66898691
33MP0006292_abnormal_olfactory_placode1.64477670
34MP0003646_muscle_fatigue1.61287088
35MP0004133_heterotaxia1.60984359
36MP0005584_abnormal_enzyme/coenzyme_acti1.58660339
37MP0004142_abnormal_muscle_tone1.55068841
38MP0001984_abnormal_olfaction1.54868289
39MP0000569_abnormal_digit_pigmentation1.52987372
40MP0002837_dystrophic_cardiac_calcinosis1.51545503
41MP0000372_irregular_coat_pigmentation1.49437749
42MP0001968_abnormal_touch/_nociception1.47160692
43MP0002938_white_spotting1.42707510
44MP0005084_abnormal_gallbladder_morpholo1.39644564
45MP0006036_abnormal_mitochondrial_physio1.39337669
46MP0000631_abnormal_neuroendocrine_gland1.37741163
47MP0005319_abnormal_enzyme/_coenzyme1.34435574
48MP0002653_abnormal_ependyma_morphology1.33631345
49MP0003880_abnormal_central_pattern1.33623333
50MP0003806_abnormal_nucleotide_metabolis1.31365723
51MP0002168_other_aberrant_phenotype1.25770756
52MP0002272_abnormal_nervous_system1.22809493
53MP0000230_abnormal_systemic_arterial1.22656969
54MP0009046_muscle_twitch1.21965150
55MP0002736_abnormal_nociception_after1.21873621
56MP0001986_abnormal_taste_sensitivity1.21584627
57MP0005645_abnormal_hypothalamus_physiol1.21312279
58MP0002928_abnormal_bile_duct1.20715037
59MP0001501_abnormal_sleep_pattern1.17925334
60MP0005075_abnormal_melanosome_morpholog1.17860668
61MP0002876_abnormal_thyroid_physiology1.17686058
62MP0009745_abnormal_behavioral_response1.17377920
63MP0006276_abnormal_autonomic_nervous1.15576624
64MP0001486_abnormal_startle_reflex1.14534370
65MP0005646_abnormal_pituitary_gland1.13671098
66MP0002135_abnormal_kidney_morphology1.12459719
67MP0001529_abnormal_vocalization1.12354482
68MP0003787_abnormal_imprinting1.11420520
69MP0003300_gastrointestinal_ulcer1.10243226
70MP0003136_yellow_coat_color1.08279040
71MP0000026_abnormal_inner_ear1.06960827
72MP0005670_abnormal_white_adipose1.06618135
73MP0000427_abnormal_hair_cycle1.04782534
74MP0005535_abnormal_body_temperature1.03650475
75MP0002638_abnormal_pupillary_reflex1.02661889
76MP0001764_abnormal_homeostasis1.02349667
77MP0005379_endocrine/exocrine_gland_phen1.02181418
78MP0001270_distended_abdomen0.99348036
79MP0005666_abnormal_adipose_tissue0.98246458
80MP0005195_abnormal_posterior_eye0.94653343
81MP0005174_abnormal_tail_pigmentation0.94619939
82MP0005395_other_phenotype0.93495425
83MP0004147_increased_porphyrin_level0.93099925
84MP0002896_abnormal_bone_mineralization0.92163095
85MP0002751_abnormal_autonomic_nervous0.92119669
86MP0000566_synostosis0.89802147
87MP0003890_abnormal_embryonic-extraembry0.89751237
88MP0001905_abnormal_dopamine_level0.88089658
89MP0002572_abnormal_emotion/affect_behav0.87394078
90MP0002118_abnormal_lipid_homeostasis0.87320974
91MP0002160_abnormal_reproductive_system0.86555063
92MP0002557_abnormal_social/conspecific_i0.86431559
93MP0000778_abnormal_nervous_system0.84685782
94MP0003938_abnormal_ear_development0.83748374
95MP0002234_abnormal_pharynx_morphology0.83252618
96MP0001944_abnormal_pancreas_morphology0.83195910
97MP0001324_abnormal_eye_pigmentation0.83053870
98MP0001666_abnormal_nutrient_absorption0.82866078
99MP0004924_abnormal_behavior0.82520076
100MP0005386_behavior/neurological_phenoty0.82520076
101MP0002089_abnormal_postnatal_growth/wei0.81839424
102MP0004264_abnormal_extraembryonic_tissu0.81444086
103MP0003122_maternal_imprinting0.81433858
104MP0008789_abnormal_olfactory_epithelium0.81278354
105MP0002163_abnormal_gland_morphology0.78235435
106MP0002067_abnormal_sensory_capabilities0.77782774
107MP0003191_abnormal_cellular_cholesterol0.77717722
108MP0002752_abnormal_somatic_nervous0.77602498
109MP0005389_reproductive_system_phenotype0.77384300
110MP0004215_abnormal_myocardial_fiber0.77250604
111MP0009642_abnormal_blood_homeostasis0.76334857
112MP0002277_abnormal_respiratory_mucosa0.75068697
113MP0002064_seizures0.74850263
114MP0003121_genomic_imprinting0.74095936
115MP0000383_abnormal_hair_follicle0.73923238
116MP0002095_abnormal_skin_pigmentation0.73847383
117MP0005408_hypopigmentation0.73403849
118MP0003283_abnormal_digestive_organ0.71185063
119MP0000747_muscle_weakness0.69620917
120MP0003638_abnormal_response/metabolism_0.69521922
121MP0003172_abnormal_lysosome_physiology0.69067492
122MP0005220_abnormal_exocrine_pancreas0.69063739
123MP0010234_abnormal_vibrissa_follicle0.68820061
124MP0009764_decreased_sensitivity_to0.66347213
125MP0001485_abnormal_pinna_reflex0.64808494
126MP0000609_abnormal_liver_physiology0.63868562
127MP0010329_abnormal_lipoprotein_level0.63376806
128MP0001661_extended_life_span0.60268943
129MP0010386_abnormal_urinary_bladder0.59236768
130MP0000371_diluted_coat_color0.57490466
131MP0003329_amyloid_beta_deposits0.55158314
132MP0000598_abnormal_liver_morphology0.52365571
133MP0002115_abnormal_skeleton_extremities0.52352357
134MP0002796_impaired_skin_barrier0.51775463
135MP0003315_abnormal_perineum_morphology0.50855005
136MP0003959_abnormal_lean_body0.49946564
137MP0008469_abnormal_protein_level0.49391105
138MP0003879_abnormal_hair_cell0.49359924
139MP0005165_increased_susceptibility_to0.47518452
140MP0002078_abnormal_glucose_homeostasis0.47180616
141MP0000678_abnormal_parathyroid_gland0.47042407
142MP0004484_altered_response_of0.46659116
143MP0004742_abnormal_vestibular_system0.46367041
144MP0003221_abnormal_cardiomyocyte_apopto0.46191997
145MP0003953_abnormal_hormone_level0.45550855
146MP0003718_maternal_effect0.45187719
147MP0003795_abnormal_bone_structure0.43070409
148MP0002069_abnormal_eating/drinking_beha0.43039532
149MP0006035_abnormal_mitochondrial_morpho0.42683934
150MP0001663_abnormal_digestive_system0.42659981
151MP0005501_abnormal_skin_physiology0.40089688
152MP0000163_abnormal_cartilage_morphology0.39532757
153MP0009672_abnormal_birth_weight0.37774564
154MP0002998_abnormal_bone_remodeling0.36545373
155MP0005375_adipose_tissue_phenotype0.35154828
156MP0001963_abnormal_hearing_physiology0.30432654
157MP0002098_abnormal_vibrissa_morphology0.29975421
158MP0000534_abnormal_ureter_morphology0.29850292
159MP0001731_abnormal_postnatal_growth0.29417279
160MP0005381_digestive/alimentary_phenotyp0.28762489
161MP0004858_abnormal_nervous_system0.25270484
162MP0002113_abnormal_skeleton_development0.25010306
163MP0002971_abnormal_brown_adipose0.25005348
164MP0005310_abnormal_salivary_gland0.24964765
165MP0005167_abnormal_blood-brain_barrier0.24474611
166MP0002295_abnormal_pulmonary_circulatio0.24177994

Predicted human phenotypes

RankGene SetZ-score
1Increased circulating renin level (HP:0000848)7.88751274
2Hypokalemic alkalosis (HP:0001949)7.45073357
3Metabolic alkalosis (HP:0200114)7.43839079
4Gout (HP:0001997)7.08647443
5Hypomagnesemia (HP:0002917)6.98831161
6Hyperactive renin-angiotensin system (HP:0000841)6.86021945
7Polyuria (HP:0000103)6.71451214
8Abnormality of chloride homeostasis (HP:0011422)6.30250953
9Abnormal urine output (HP:0012590)6.29328859
10Abnormality of renal excretion (HP:0011036)5.96950718
11Abnormality of magnesium homeostasis (HP:0004921)5.91716975
12Abnormal drinking behavior (HP:0030082)5.48717040
13Polydipsia (HP:0001959)5.48717040
14Proximal tubulopathy (HP:0000114)5.47856066
15Increased purine levels (HP:0004368)5.09816200
16Hyperuricemia (HP:0002149)5.09816200
17Tetany (HP:0001281)4.94730810
18Alkalosis (HP:0001948)4.89511216
19Abnormality of renin-angiotensin system (HP:0000847)4.86917336
20Hyperglycinuria (HP:0003108)4.84252680
21Renal salt wasting (HP:0000127)4.82315961
22Hyperaldosteronism (HP:0000859)4.73614974
23Abnormality of glutamine family amino acid metabolism (HP:0010902)4.70379591
24Abnormality of purine metabolism (HP:0004352)4.47817108
25Generalized aminoaciduria (HP:0002909)4.20719258
26Hypercalciuria (HP:0002150)4.06787755
27Abnormality of glycine metabolism (HP:0010895)3.97042415
28Abnormality of serine family amino acid metabolism (HP:0010894)3.97042415
29Abnormality of urine glucose concentration (HP:0011016)3.74458978
30Glycosuria (HP:0003076)3.74458978
31Hypokalemia (HP:0002900)3.73568885
32Ketoacidosis (HP:0001993)3.71831110
33Renal tubular acidosis (HP:0001947)3.58236597
34Pancreatic cysts (HP:0001737)3.40995909
35Abnormality of nucleobase metabolism (HP:0010932)3.33292819
36Hyperphosphaturia (HP:0003109)3.29710996
37Ketosis (HP:0001946)3.28936482
38Delayed epiphyseal ossification (HP:0002663)3.13574746
39Abnormality of potassium homeostasis (HP:0011042)3.12458456
40Abnormal urine phosphate concentration (HP:0012599)3.12040225
41Hydroxyprolinuria (HP:0003080)3.10511006
42Abnormality of proline metabolism (HP:0010907)3.10511006
43Abnormality of the renal medulla (HP:0100957)3.06645699
44Abnormality of the renal cortex (HP:0011035)2.99112387
45Nephrocalcinosis (HP:0000121)2.92190806
46Pancreatic fibrosis (HP:0100732)2.89304984
47Nephrolithiasis (HP:0000787)2.82911721
48Abnormality of fatty-acid metabolism (HP:0004359)2.81637356
49Abnormality of aspartate family amino acid metabolism (HP:0010899)2.78502949
50Hyperglycinemia (HP:0002154)2.77622016
51Molar tooth sign on MRI (HP:0002419)2.75858056
52Abnormality of midbrain morphology (HP:0002418)2.75858056
53Hypothermia (HP:0002045)2.73702211
54True hermaphroditism (HP:0010459)2.68905797
55Type II lissencephaly (HP:0007260)2.67427667
56Hypophosphatemia (HP:0002148)2.63884131
57Rickets (HP:0002748)2.58728497
58Congenital stationary night blindness (HP:0007642)2.58646533
59Delayed CNS myelination (HP:0002188)2.55851061
60Metaphyseal cupping (HP:0003021)2.53256180
61Nephrogenic diabetes insipidus (HP:0009806)2.50915798
62Vascular calcification (HP:0004934)2.49028377
63Dehydration (HP:0001944)2.47104985
64Hyperammonemia (HP:0001987)2.43440790
65Abnormality of sodium homeostasis (HP:0010931)2.42908360
66Widely patent fontanelles and sutures (HP:0004492)2.41708477
67Nephronophthisis (HP:0000090)2.41220126
68Hyponatremia (HP:0002902)2.38294918
69Dicarboxylic aciduria (HP:0003215)2.31625521
70Abnormality of dicarboxylic acid metabolism (HP:0010995)2.31625521
71Abnormality of renal resorption (HP:0011038)2.28264787
72Abnormality of aromatic amino acid family metabolism (HP:0004338)2.27721862
73Metabolic acidosis (HP:0001942)2.26603469
74Vacuolated lymphocytes (HP:0001922)2.26328605
75Renal cortical cysts (HP:0000803)2.26282205
76Vomiting (HP:0002013)2.25717797
77Malnutrition (HP:0004395)2.24778696
78Renal tubular dysfunction (HP:0000124)2.24732047
79Medial flaring of the eyebrow (HP:0010747)2.21798140
80Cardiovascular calcification (HP:0011915)2.21426047
81Enlarged kidneys (HP:0000105)2.18198806
82Acute necrotizing encephalopathy (HP:0006965)2.17792174
83Abnormal enzyme/coenzyme activity (HP:0012379)2.16391046
84Adrenal overactivity (HP:0002717)2.13636003
85Lipid accumulation in hepatocytes (HP:0006561)2.10562754
86Abnormality of alkaline phosphatase activity (HP:0004379)2.10513094
87Confusion (HP:0001289)2.10260859
88Mitochondrial inheritance (HP:0001427)2.09152531
89Acute encephalopathy (HP:0006846)2.08776281
90Thin bony cortex (HP:0002753)2.08072968
91Abnormality of sulfur amino acid metabolism (HP:0004339)2.06935861
92Methylmalonic acidemia (HP:0002912)2.06258611
93Cystic liver disease (HP:0006706)2.05993217
94Lethargy (HP:0001254)2.03788516
95Increased CSF lactate (HP:0002490)2.02483009
96Bilateral sensorineural hearing impairment (HP:0008619)2.01689989
97Large eyes (HP:0001090)2.01007232
98Thyroid-stimulating hormone excess (HP:0002925)2.00464760
99Methylmalonic aciduria (HP:0012120)2.00387930
100Chondrocalcinosis (HP:0000934)1.99169874
101Tubular atrophy (HP:0000092)1.98236371
102Progressive macrocephaly (HP:0004481)1.96326250
103Increased hepatocellular lipid droplets (HP:0006565)1.94915588
104Abnormal tarsal ossification (HP:0008369)1.91913151
105Tubulointerstitial fibrosis (HP:0005576)1.91177197
106Abnormality of the costochondral junction (HP:0000919)1.87146727
107Abnormality of Sharpey fibers (HP:0100685)1.85898249
108Decreased circulating renin level (HP:0003351)1.84476646
109Cerebellar dysplasia (HP:0007033)1.82349697
110Congenital, generalized hypertrichosis (HP:0004540)1.81548240
111Nausea (HP:0002018)1.81351421
112Abolished electroretinogram (ERG) (HP:0000550)1.80679074
113Lymphangioma (HP:0100764)1.79344110
114Gait imbalance (HP:0002141)1.78712775
115Abnormality of the labia minora (HP:0012880)1.78545154
116Abnormality of serum amino acid levels (HP:0003112)1.78422279
117Irritability (HP:0000737)1.77022727
118Abnormal mitochondria in muscle tissue (HP:0008316)1.76787121
119Facial shape deformation (HP:0011334)1.76769771
120Potter facies (HP:0002009)1.76769771
121Bicornuate uterus (HP:0000813)1.76417918
122Glomerulosclerosis (HP:0000096)1.72935359
123Metaphyseal irregularity (HP:0003025)1.72748561
124Genital tract atresia (HP:0001827)1.72679266
125Hepatocellular necrosis (HP:0001404)1.71874111
126Congenital primary aphakia (HP:0007707)1.71248420
127Chorioretinal atrophy (HP:0000533)1.71246180
128Elevated alkaline phosphatase (HP:0003155)1.69674375
1293-Methylglutaconic aciduria (HP:0003535)1.69668375
130Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.68752073
131Congenital hepatic fibrosis (HP:0002612)1.68393809
132Retinal dysplasia (HP:0007973)1.68169225
133Optic disc pallor (HP:0000543)1.67904002
134Pendular nystagmus (HP:0012043)1.67769042
135Hyperventilation (HP:0002883)1.66934963
136Tubulointerstitial abnormality (HP:0001969)1.66106803
137Attenuation of retinal blood vessels (HP:0007843)1.65964182
138Hepatic necrosis (HP:0002605)1.65819759
139Hypotension (HP:0002615)1.65462915
140Sclerocornea (HP:0000647)1.65398299
141Neonatal onset (HP:0003623)1.65386018
142Metaphyseal dysplasia (HP:0100255)1.65272049
143Sensorimotor neuropathy (HP:0007141)1.61977794
144Vaginal atresia (HP:0000148)1.61175103
145Abnormality of vitamin B metabolism (HP:0004340)1.61062987
146Disproportionate short-trunk short stature (HP:0003521)1.61008864
147Generalized muscle weakness (HP:0003324)1.59439209
148Abnormal number of erythroid precursors (HP:0012131)1.59344639
149Tachypnea (HP:0002789)1.59045281
150Lissencephaly (HP:0001339)1.55835878
151Chronic hepatic failure (HP:0100626)1.54918285
152Absent/shortened dynein arms (HP:0200106)1.54176004
153Dynein arm defect of respiratory motile cilia (HP:0012255)1.54176004
154Bile duct proliferation (HP:0001408)1.53689380
155Abnormal biliary tract physiology (HP:0012439)1.53689380
156Abnormality of the vitamin B12 metabolism (HP:0004341)1.48608434
157Aplasia/hypoplasia of the uterus (HP:0008684)1.47434156

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK49.20696411
2WNK38.09496402
3OXSR17.60114232
4STK394.56008277
5BCKDK2.95033469
6MAP4K22.71826263
7STK38L2.71400967
8ADRBK22.35158724
9NEK11.95902306
10SGK4941.92354713
11SGK2231.92354713
12PDK41.89772689
13PDK31.89772689
14WNK11.89057023
15BMPR1B1.84896006
16GRK11.76981430
17NUAK11.76903235
18ZAK1.49726741
19PDK21.38341077
20STK381.35254774
21MAPK131.30190729
22STK161.28937274
23TLK11.27479362
24TXK1.25261717
25PNCK1.25035796
26CASK1.16858421
27DYRK21.11354688
28FGFR21.09117062
29VRK21.08421201
30SGK21.04351205
31DAPK21.01587838
32MAP3K40.99110099
33MST1R0.97995360
34SGK30.94080284
35IRAK10.92953925
36PINK10.91697403
37MARK10.91304070
38ACVR1B0.86116458
39BRSK20.86005255
40LRRK20.84013872
41CAMKK20.82598184
42VRK10.80197938
43MST40.79341231
44FGFR40.78012536
45ADRBK10.75794793
46MKNK20.75388601
47ERBB40.69620353
48TNIK0.68273967
49MAP3K60.67356083
50NTRK30.67277887
51KIT0.66807852
52PRKCE0.66733016
53PRKCG0.66687883
54BCR0.66524653
55TRIM280.66435100
56GSK3A0.65423125
57GRK60.64604699
58TGFBR10.63888981
59TAOK30.63230915
60LATS10.62790725
61ABL20.62373310
62PASK0.62258718
63PHKG10.60456879
64PHKG20.60456879
65EPHB10.59728754
66MAP2K70.59096858
67SGK10.56573962
68PRKAA10.53881281
69NTRK20.53506940
70TSSK60.52598163
71TIE10.52135630
72MAPK110.51202625
73MAP3K120.51172280
74EIF2AK30.50789681
75MAP3K70.50356963
76IKBKB0.50115213
77PTK20.49274603
78CSNK1G20.48772161
79MKNK10.48518259
80PLK30.47956530
81NLK0.44306916
82KSR20.44167791
83STK100.43398897
84PDPK10.43322854
85RPS6KA50.42583506
86PRKD20.42322589
87TRIB30.39689696
88DYRK1B0.39480345
89PRKAA20.39438178
90ERBB30.38402129
91PAK40.37826980
92TGFBR20.37798098
93TEC0.37482899
94CSNK1G30.36664907
95MUSK0.36518756
96WEE10.36401853
97MAPKAPK50.36303786
98PLK40.35814437
99PLK20.35392448
100PRKD30.34569897
101MAP3K30.33830749
102ITK0.32895133
103CDK30.32366369
104PRKCQ0.30214437
105LATS20.29668362
106PAK30.29291573
107MAPKAPK30.29066450
108PRKCI0.28938393
109ERN10.28848029
110PDK10.28818449
111DYRK30.28645644
112PKN10.28627849
113PRKG10.27416944
114NME10.26490958
115TTK0.25949401
116PTK60.24735528
117STK110.24528870
118MAP3K20.24395040
119PIK3CA0.24295245
120CSNK1A1L0.23909110
121TAOK10.23529529
122PRKCZ0.22874552
123MET0.22833660
124NME20.22545421
125GRK70.22091203
126NTRK10.21450156
127CAMK2A0.21357301
128PTK2B0.19980558
129MAP2K40.18647762
130MOS0.18100688
131FER0.18003800
132RIPK10.15436466
133EPHA40.14698574
134INSRR0.14455376
135PRKCD0.13924284
136PIM10.13440169
137PRKACG0.13329340
138PRKCH0.13256977
139JAK20.12915557
140MAP3K130.12226705
141AKT20.09712734
142BMPR20.09414861
143PRKACA0.09020606
144PRKCA0.08750669
145CSNK1G10.07812879
146MYLK0.07664003
147MAPK120.07228384
148STK30.06531907
149KSR10.06529528
150SCYL20.06505804
151IRAK20.05979167
152FRK0.04711232
153BMX0.04210799
154MINK10.04094999
155MAP3K90.03600907
156MAP3K80.03483965
157ROCK10.03323509
158PAK60.02175005
159MAPK150.01884368
160MELK0.01723247
161MAP2K30.01291202
162BRAF0.01186373
163MAP3K110.00289936
164RPS6KA3-0.0147333
165EEF2K-0.0140083
166MAP3K14-0.0094247
167ABL1-0.0056026
168CSNK1A1-0.0046118

Predicted pathways (KEGG)

RankGene SetZ-score
1Butanoate metabolism_Homo sapiens_hsa006503.85991472
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.71296325
3Cyanoamino acid metabolism_Homo sapiens_hsa004603.69491840
4Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049643.44721705
5Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.31866290
6Propanoate metabolism_Homo sapiens_hsa006403.30384013
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006303.29739693
8Pentose and glucuronate interconversions_Homo sapiens_hsa000402.94973470
92-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.71754675
10Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.56087633
11Peroxisome_Homo sapiens_hsa041462.54079734
12Protein export_Homo sapiens_hsa030602.50379949
13Pyruvate metabolism_Homo sapiens_hsa006202.48928137
14Phototransduction_Homo sapiens_hsa047442.40192341
15Fatty acid degradation_Homo sapiens_hsa000712.39200358
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.39018786
17Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.35138787
18Collecting duct acid secretion_Homo sapiens_hsa049662.31408066
19Tryptophan metabolism_Homo sapiens_hsa003802.29397868
20Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.17233880
21Linoleic acid metabolism_Homo sapiens_hsa005912.13316022
22* Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.08354371
23Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.08279535
24beta-Alanine metabolism_Homo sapiens_hsa004102.02723535
25Vitamin digestion and absorption_Homo sapiens_hsa049771.93797887
26Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.89548462
27Fatty acid metabolism_Homo sapiens_hsa012121.79161148
28Carbon metabolism_Homo sapiens_hsa012001.69408328
29Ether lipid metabolism_Homo sapiens_hsa005651.68321118
30Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.65015933
31Glutathione metabolism_Homo sapiens_hsa004801.64079529
32Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.63006498
33Sulfur metabolism_Homo sapiens_hsa009201.62549930
34Bile secretion_Homo sapiens_hsa049761.62312593
35RNA polymerase_Homo sapiens_hsa030201.59702400
36Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.56564769
37Arginine and proline metabolism_Homo sapiens_hsa003301.53762093
38Homologous recombination_Homo sapiens_hsa034401.53309775
39Basal transcription factors_Homo sapiens_hsa030221.48999072
40Nicotine addiction_Homo sapiens_hsa050331.47826533
41Other glycan degradation_Homo sapiens_hsa005111.39934936
42Fanconi anemia pathway_Homo sapiens_hsa034601.35362350
43Ribosome_Homo sapiens_hsa030101.34192397
44Lysine degradation_Homo sapiens_hsa003101.33822093
45Intestinal immune network for IgA production_Homo sapiens_hsa046721.23052556
46Mineral absorption_Homo sapiens_hsa049781.22890729
47Protein digestion and absorption_Homo sapiens_hsa049741.21500841
48Arginine biosynthesis_Homo sapiens_hsa002201.21244505
49Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.20843520
50PPAR signaling pathway_Homo sapiens_hsa033201.20601399
51Primary bile acid biosynthesis_Homo sapiens_hsa001201.19244260
52Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.18658733
53Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.11383598
54Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.10224217
55Proteasome_Homo sapiens_hsa030501.08962605
56Starch and sucrose metabolism_Homo sapiens_hsa005001.08636543
57Histidine metabolism_Homo sapiens_hsa003401.08271611
58RNA degradation_Homo sapiens_hsa030181.06288495
59Folate biosynthesis_Homo sapiens_hsa007901.05266437
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.04824655
61Biosynthesis of amino acids_Homo sapiens_hsa012301.04489240
62Nitrogen metabolism_Homo sapiens_hsa009101.03206773
63Selenocompound metabolism_Homo sapiens_hsa004501.02496864
64Caffeine metabolism_Homo sapiens_hsa002321.01810806
65Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.99773581
66Phenylalanine metabolism_Homo sapiens_hsa003600.98079486
67Regulation of autophagy_Homo sapiens_hsa041400.94944623
68Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.93872099
69Glycerolipid metabolism_Homo sapiens_hsa005610.92916197
70Taste transduction_Homo sapiens_hsa047420.86656566
71Morphine addiction_Homo sapiens_hsa050320.83559471
72Olfactory transduction_Homo sapiens_hsa047400.82599537
73Fructose and mannose metabolism_Homo sapiens_hsa000510.82051379
74Primary immunodeficiency_Homo sapiens_hsa053400.81572573
75Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80037832
76Cysteine and methionine metabolism_Homo sapiens_hsa002700.79436316
77Asthma_Homo sapiens_hsa053100.79316684
78Oxidative phosphorylation_Homo sapiens_hsa001900.72779258
79Insulin secretion_Homo sapiens_hsa049110.71852312
80Renin-angiotensin system_Homo sapiens_hsa046140.70174625
81Serotonergic synapse_Homo sapiens_hsa047260.69148135
82GABAergic synapse_Homo sapiens_hsa047270.67648950
83Steroid hormone biosynthesis_Homo sapiens_hsa001400.67000767
84Fatty acid elongation_Homo sapiens_hsa000620.65423818
85Type I diabetes mellitus_Homo sapiens_hsa049400.64248564
86Carbohydrate digestion and absorption_Homo sapiens_hsa049730.64244486
87Chemical carcinogenesis_Homo sapiens_hsa052040.60493449
88Pentose phosphate pathway_Homo sapiens_hsa000300.57713115
89Lysosome_Homo sapiens_hsa041420.57443554
90Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.57204639
91Metabolic pathways_Homo sapiens_hsa011000.55766274
92Maturity onset diabetes of the young_Homo sapiens_hsa049500.55744573
93Purine metabolism_Homo sapiens_hsa002300.55311520
94Drug metabolism - other enzymes_Homo sapiens_hsa009830.55073510
95Thyroid hormone synthesis_Homo sapiens_hsa049180.52416373
96Fat digestion and absorption_Homo sapiens_hsa049750.52050044
97Glycosaminoglycan degradation_Homo sapiens_hsa005310.50036506
98Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.49976405
99Circadian rhythm_Homo sapiens_hsa047100.46390328
100Retinol metabolism_Homo sapiens_hsa008300.41557785
101Pyrimidine metabolism_Homo sapiens_hsa002400.41238766
102Gastric acid secretion_Homo sapiens_hsa049710.40622988
103Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.40374581
104Circadian entrainment_Homo sapiens_hsa047130.39886112
105Non-homologous end-joining_Homo sapiens_hsa034500.39507975
106Glutamatergic synapse_Homo sapiens_hsa047240.38072338
107Parkinsons disease_Homo sapiens_hsa050120.36718258
108Autoimmune thyroid disease_Homo sapiens_hsa053200.35953989
109Arachidonic acid metabolism_Homo sapiens_hsa005900.35395554
110Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.34559212
111Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.33310129
112Vibrio cholerae infection_Homo sapiens_hsa051100.31056658
113Synaptic vesicle cycle_Homo sapiens_hsa047210.26781005
114Tyrosine metabolism_Homo sapiens_hsa003500.26283058
115Choline metabolism in cancer_Homo sapiens_hsa052310.25757910
116Steroid biosynthesis_Homo sapiens_hsa001000.25481521
117Sulfur relay system_Homo sapiens_hsa041220.25460653
118Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.17908741
119ABC transporters_Homo sapiens_hsa020100.16211741
120Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.14771117
121Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.13667781
122Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.13321397
123alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.12182448
124Sphingolipid metabolism_Homo sapiens_hsa006000.11712599
125Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.09941447
126Cardiac muscle contraction_Homo sapiens_hsa042600.08813967
127Galactose metabolism_Homo sapiens_hsa000520.08024235
128Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.06331431
129Alzheimers disease_Homo sapiens_hsa050100.06159565
130Insulin resistance_Homo sapiens_hsa049310.05825895
131Adipocytokine signaling pathway_Homo sapiens_hsa049200.04680229
132Rheumatoid arthritis_Homo sapiens_hsa053230.04124848
133Bladder cancer_Homo sapiens_hsa052190.03475226
134AMPK signaling pathway_Homo sapiens_hsa041520.01210039
135Huntingtons disease_Homo sapiens_hsa050160.01100226
136FoxO signaling pathway_Homo sapiens_hsa04068-0.0861598
137Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601-0.0613059
138One carbon pool by folate_Homo sapiens_hsa00670-0.0323502
139Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0316031
140Glucagon signaling pathway_Homo sapiens_hsa04922-0.0294667

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »