| 1 | Birth length less than 3rd percentile (HP:0003561) | 6.22109370 |
| 2 | Breast hypoplasia (HP:0003187) | 3.55024749 |
| 3 | Chromsome breakage (HP:0040012) | 3.09511918 |
| 4 | Facial hemangioma (HP:0000329) | 3.08377147 |
| 5 | Patellar aplasia (HP:0006443) | 2.94423846 |
| 6 | Acute myeloid leukemia (HP:0004808) | 2.91151058 |
| 7 | Abnormality of chromosome stability (HP:0003220) | 2.89522026 |
| 8 | Combined immunodeficiency (HP:0005387) | 2.85361491 |
| 9 | Agnosia (HP:0010524) | 2.85078132 |
| 10 | Cortical dysplasia (HP:0002539) | 2.79344523 |
| 11 | Thrombocytosis (HP:0001894) | 2.78070429 |
| 12 | Severe combined immunodeficiency (HP:0004430) | 2.77129226 |
| 13 | Increased hepatocellular lipid droplets (HP:0006565) | 2.76493115 |
| 14 | Oral leukoplakia (HP:0002745) | 2.75130632 |
| 15 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.74315210 |
| 16 | Cutaneous melanoma (HP:0012056) | 2.73112391 |
| 17 | Pancreatic cysts (HP:0001737) | 2.71334831 |
| 18 | Abnormality of the labia minora (HP:0012880) | 2.70815784 |
| 19 | Entropion (HP:0000621) | 2.68232592 |
| 20 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.67379664 |
| 21 | Slender long bone (HP:0003100) | 2.63550621 |
| 22 | Lipid accumulation in hepatocytes (HP:0006561) | 2.62230142 |
| 23 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.61636654 |
| 24 | Thyroiditis (HP:0100646) | 2.56054777 |
| 25 | Deviation of the thumb (HP:0009603) | 2.54571504 |
| 26 | Embryonal renal neoplasm (HP:0011794) | 2.54567916 |
| 27 | Neoplasm of the adrenal cortex (HP:0100641) | 2.50681276 |
| 28 | High pitched voice (HP:0001620) | 2.47175949 |
| 29 | Short 4th metacarpal (HP:0010044) | 2.47023903 |
| 30 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.47023903 |
| 31 | Abnormality of the anterior horn cell (HP:0006802) | 2.46965630 |
| 32 | Degeneration of anterior horn cells (HP:0002398) | 2.46965630 |
| 33 | Selective tooth agenesis (HP:0001592) | 2.46285366 |
| 34 | True hermaphroditism (HP:0010459) | 2.46190060 |
| 35 | Proximal placement of thumb (HP:0009623) | 2.45676260 |
| 36 | IgG deficiency (HP:0004315) | 2.40101929 |
| 37 | Microvesicular hepatic steatosis (HP:0001414) | 2.37833137 |
| 38 | Impulsivity (HP:0100710) | 2.37404299 |
| 39 | Aplastic anemia (HP:0001915) | 2.37164077 |
| 40 | Abnormality of methionine metabolism (HP:0010901) | 2.36985512 |
| 41 | Pancreatic fibrosis (HP:0100732) | 2.34168740 |
| 42 | B lymphocytopenia (HP:0010976) | 2.33386609 |
| 43 | Volvulus (HP:0002580) | 2.32739002 |
| 44 | Conjunctival telangiectasia (HP:0000524) | 2.32460946 |
| 45 | Squamous cell carcinoma (HP:0002860) | 2.31876181 |
| 46 | Abnormal lung lobation (HP:0002101) | 2.31801417 |
| 47 | Poikiloderma (HP:0001029) | 2.29508168 |
| 48 | Medulloblastoma (HP:0002885) | 2.28559609 |
| 49 | Ependymoma (HP:0002888) | 2.28550036 |
| 50 | Premature graying of hair (HP:0002216) | 2.27880318 |
| 51 | Myelodysplasia (HP:0002863) | 2.26010340 |
| 52 | Neoplasm of the adrenal gland (HP:0100631) | 2.21335920 |
| 53 | Hypoplasia of the pons (HP:0012110) | 2.18648296 |
| 54 | Abnormality of the pons (HP:0007361) | 2.18446139 |
| 55 | Cellular immunodeficiency (HP:0005374) | 2.17309560 |
| 56 | Increased CSF lactate (HP:0002490) | 2.15354213 |
| 57 | Poor head control (HP:0002421) | 2.14171011 |
| 58 | Recurrent viral infections (HP:0004429) | 2.14132640 |
| 59 | Pancytopenia (HP:0001876) | 2.13949557 |
| 60 | Ankle contracture (HP:0006466) | 2.13390677 |
| 61 | Disinhibition (HP:0000734) | 2.12291366 |
| 62 | Ectopic kidney (HP:0000086) | 2.11980459 |
| 63 | Rough bone trabeculation (HP:0100670) | 2.09622165 |
| 64 | Carpal bone hypoplasia (HP:0001498) | 2.07406585 |
| 65 | Meckel diverticulum (HP:0002245) | 2.06938359 |
| 66 | Abnormality of the duodenum (HP:0002246) | 2.06901987 |
| 67 | Deep philtrum (HP:0002002) | 2.06026313 |
| 68 | Atresia of the external auditory canal (HP:0000413) | 2.05597811 |
| 69 | Increased nuchal translucency (HP:0010880) | 2.05561773 |
| 70 | Abnormality of the metopic suture (HP:0005556) | 2.03558987 |
| 71 | Neoplasm of the pancreas (HP:0002894) | 2.01460086 |
| 72 | Abnormality of B cell number (HP:0010975) | 2.00445921 |
| 73 | Wrist flexion contracture (HP:0001239) | 1.99890935 |
| 74 | Microtia (HP:0008551) | 1.99843312 |
| 75 | Increased serum lactate (HP:0002151) | 1.99170088 |
| 76 | Colon cancer (HP:0003003) | 1.98416616 |
| 77 | Prominent metopic ridge (HP:0005487) | 1.98102131 |
| 78 | Large for gestational age (HP:0001520) | 1.97566842 |
| 79 | Acute encephalopathy (HP:0006846) | 1.96775706 |
| 80 | Supernumerary spleens (HP:0009799) | 1.96768216 |
| 81 | Acute necrotizing encephalopathy (HP:0006965) | 1.96567663 |
| 82 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.96555644 |
| 83 | Cafe-au-lait spot (HP:0000957) | 1.95034283 |
| 84 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.94809056 |
| 85 | Abnormality of the ileum (HP:0001549) | 1.93762022 |
| 86 | Methylmalonic acidemia (HP:0002912) | 1.93555136 |
| 87 | Abnormality of the 4th metacarpal (HP:0010012) | 1.93192697 |
| 88 | Sloping forehead (HP:0000340) | 1.92494838 |
| 89 | Intestinal atresia (HP:0011100) | 1.92457127 |
| 90 | Cerebral edema (HP:0002181) | 1.92165061 |
| 91 | Cellulitis (HP:0100658) | 1.91497056 |
| 92 | Bone marrow hypocellularity (HP:0005528) | 1.91219741 |
| 93 | Protrusio acetabuli (HP:0003179) | 1.90458780 |
| 94 | Lymphoma (HP:0002665) | 1.90004353 |
| 95 | Ovarian neoplasm (HP:0100615) | 1.89938885 |
| 96 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.89896176 |
| 97 | Abnormality of the preputium (HP:0100587) | 1.89176862 |
| 98 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.89152785 |
| 99 | Freckling (HP:0001480) | 1.88937367 |
| 100 | Thoracolumbar scoliosis (HP:0002944) | 1.88911183 |
| 101 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.88804761 |
| 102 | Progressive macrocephaly (HP:0004481) | 1.88799724 |
| 103 | Increased density of long bones (HP:0006392) | 1.86662925 |
| 104 | Aseptic necrosis (HP:0010885) | 1.86389683 |
| 105 | Absent radius (HP:0003974) | 1.86382499 |
| 106 | Hypoproteinemia (HP:0003075) | 1.86080943 |
| 107 | Horseshoe kidney (HP:0000085) | 1.83778627 |
| 108 | Mitochondrial inheritance (HP:0001427) | 1.83634697 |
| 109 | Biconcave vertebral bodies (HP:0004586) | 1.83368167 |
| 110 | Molar tooth sign on MRI (HP:0002419) | 1.82882234 |
| 111 | Abnormality of midbrain morphology (HP:0002418) | 1.82882234 |
| 112 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.80746509 |
| 113 | Long clavicles (HP:0000890) | 1.80700849 |
| 114 | Reticulocytopenia (HP:0001896) | 1.79630374 |
| 115 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.79096188 |
| 116 | Optic nerve coloboma (HP:0000588) | 1.78498152 |
| 117 | Megaloblastic anemia (HP:0001889) | 1.77588909 |
| 118 | Rhabdomyosarcoma (HP:0002859) | 1.76964028 |
| 119 | Clubbing of toes (HP:0100760) | 1.75830125 |
| 120 | Overlapping toe (HP:0001845) | 1.75287540 |
| 121 | Anencephaly (HP:0002323) | 1.74206897 |
| 122 | Eosinophilia (HP:0001880) | 1.73826790 |
| 123 | Basal cell carcinoma (HP:0002671) | 1.73826227 |
| 124 | Abnormality of DNA repair (HP:0003254) | 1.73625456 |
| 125 | IgM deficiency (HP:0002850) | 1.73232923 |
| 126 | Hypoplasia of the thymus (HP:0000778) | 1.72872311 |
| 127 | Oligodactyly (hands) (HP:0001180) | 1.72856372 |
| 128 | Hypothermia (HP:0002045) | 1.72467515 |
| 129 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.71361036 |
| 130 | Capillary hemangiomas (HP:0005306) | 1.71109584 |
| 131 | Small intestinal stenosis (HP:0012848) | 1.70972488 |
| 132 | Duodenal stenosis (HP:0100867) | 1.70972488 |
| 133 | Biliary tract neoplasm (HP:0100574) | 1.70953192 |
| 134 | Teleangiectasia of the skin (HP:0100585) | 1.70472083 |
| 135 | Type I transferrin isoform profile (HP:0003642) | 1.69376092 |
| 136 | Pendular nystagmus (HP:0012043) | 1.69158771 |
| 137 | Dandy-Walker malformation (HP:0001305) | 1.68860092 |
| 138 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.68296136 |
| 139 | Osteolytic defects of the hand bones (HP:0009699) | 1.68296136 |
| 140 | Thyroid carcinoma (HP:0002890) | 1.67408126 |
| 141 | Pelvic girdle muscle weakness (HP:0003749) | 1.66939319 |
| 142 | Aplasia involving forearm bones (HP:0009822) | 1.66562550 |
| 143 | Absent forearm bone (HP:0003953) | 1.66562550 |
| 144 | Abnormal spermatogenesis (HP:0008669) | 1.66495586 |
| 145 | Lactic acidosis (HP:0003128) | 1.66388079 |
| 146 | Breast carcinoma (HP:0003002) | 1.66304518 |
| 147 | Tracheoesophageal fistula (HP:0002575) | 1.66242898 |
| 148 | Glioma (HP:0009733) | 1.66229776 |
| 149 | Increased serum pyruvate (HP:0003542) | 1.66151794 |
| 150 | Long eyelashes (HP:0000527) | 1.65387095 |
| 151 | Methylmalonic aciduria (HP:0012120) | 1.65205351 |
| 152 | Cutis marmorata (HP:0000965) | 1.65054621 |
| 153 | Hypoglycemic seizures (HP:0002173) | 1.64938216 |
| 154 | Preaxial hand polydactyly (HP:0001177) | 1.64822864 |
| 155 | Prominent nose (HP:0000448) | 1.64614077 |
| 156 | Hematochezia (HP:0002573) | 1.63759953 |
| 157 | Progressive inability to walk (HP:0002505) | 1.63308007 |
| 158 | Neoplasm of the small intestine (HP:0100833) | 1.62811575 |
| 159 | Renal Fanconi syndrome (HP:0001994) | 1.62700770 |
| 160 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.62693917 |
| 161 | Recurrent abscess formation (HP:0002722) | 1.62626444 |
| 162 | Chronic otitis media (HP:0000389) | 1.62614053 |
| 163 | Glossoptosis (HP:0000162) | 1.62486364 |
| 164 | Neoplasm of the colon (HP:0100273) | 1.62145622 |
| 165 | Spastic diplegia (HP:0001264) | 1.61585088 |
| 166 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.61226058 |
| 167 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.60445932 |
MIS12 
