MKI67

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic sister chromatid cohesion (GO:0007064)6.13419461
2sister chromatid segregation (GO:0000819)5.97060236
3mitotic chromosome condensation (GO:0007076)5.92526736
4regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450915.88393146
5protein localization to kinetochore (GO:0034501)5.83006258
6mitotic sister chromatid segregation (GO:0000070)5.57302933
7kinetochore organization (GO:0051383)5.56235942
8DNA unwinding involved in DNA replication (GO:0006268)5.41430232
9regulation of DNA endoreduplication (GO:0032875)5.36804991
10nuclear pore complex assembly (GO:0051292)5.25326397
11protein localization to chromosome, centromeric region (GO:0071459)5.24769710
12nuclear pore organization (GO:0006999)4.93246195
13regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.40802746
14positive regulation of mitotic sister chromatid separation (GO:1901970)4.40239434
15positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.40239434
16positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.40239434
17regulation of histone H3-K9 methylation (GO:0051570)4.38887089
18meiotic chromosome segregation (GO:0045132)4.38422571
19attachment of spindle microtubules to kinetochore (GO:0008608)4.35244576
20DNA topological change (GO:0006265)4.23793734
21kinetochore assembly (GO:0051382)4.23118562
22positive regulation of chromosome segregation (GO:0051984)4.07346481
23regulation of spindle organization (GO:0090224)4.05269929
24chromosome condensation (GO:0030261)4.01363365
25regulation of sister chromatid cohesion (GO:0007063)4.00506432
26pore complex assembly (GO:0046931)3.95385979
27mitotic nuclear envelope disassembly (GO:0007077)3.94532213
28mitotic metaphase plate congression (GO:0007080)3.90753965
29protoporphyrinogen IX metabolic process (GO:0046501)3.88036384
30negative regulation of histone methylation (GO:0031061)3.87535350
31metaphase plate congression (GO:0051310)3.87180065
32chromatin assembly (GO:0031497)3.86322557
33DNA geometric change (GO:0032392)3.85910086
34chromatin assembly or disassembly (GO:0006333)3.85091611
35DNA duplex unwinding (GO:0032508)3.84702946
36DNA ligation (GO:0006266)3.83979207
37protein localization to chromosome (GO:0034502)3.83251941
38regulation of mitotic spindle organization (GO:0060236)3.80313377
39chromosome segregation (GO:0007059)3.76216169
40DNA replication-dependent nucleosome assembly (GO:0006335)3.73323374
41DNA replication-dependent nucleosome organization (GO:0034723)3.73323374
42mitotic recombination (GO:0006312)3.72924773
43regulation of centriole replication (GO:0046599)3.71588373
44V(D)J recombination (GO:0033151)3.71143491
45regulation of RNA export from nucleus (GO:0046831)3.70859243
46membrane disassembly (GO:0030397)3.70770001
47nuclear envelope disassembly (GO:0051081)3.70770001
48establishment of chromosome localization (GO:0051303)3.70490714
49CENP-A containing nucleosome assembly (GO:0034080)3.66450345
50dosage compensation (GO:0007549)3.64502197
51DNA replication-independent nucleosome organization (GO:0034724)3.64077368
52DNA replication-independent nucleosome assembly (GO:0006336)3.64077368
53translesion synthesis (GO:0019985)3.64050256
54chromatin remodeling at centromere (GO:0031055)3.60402560
55negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.58744286
56heterochromatin organization (GO:0070828)3.58253512
57DNA replication initiation (GO:0006270)3.57152018
58DNA strand elongation involved in DNA replication (GO:0006271)3.56399029
59DNA packaging (GO:0006323)3.56088512
60regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.53740300
61microtubule depolymerization (GO:0007019)3.52163846
62DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.51290464
63DNA conformation change (GO:0071103)3.49120318
64regulation of chromosome segregation (GO:0051983)3.49030627
65protoporphyrinogen IX biosynthetic process (GO:0006782)3.46203919
66nucleosome assembly (GO:0006334)3.40522485
67non-recombinational repair (GO:0000726)3.39834107
68double-strand break repair via nonhomologous end joining (GO:0006303)3.39834107
69DNA strand elongation (GO:0022616)3.38989855
70regulation of mitotic metaphase/anaphase transition (GO:0030071)3.38427903
71regulation of centrosome cycle (GO:0046605)3.37969339
72positive regulation of DNA-dependent DNA replication (GO:2000105)3.37511687
73spliceosomal tri-snRNP complex assembly (GO:0000244)3.37425652
74DNA replication checkpoint (GO:0000076)3.36925495
75telomere maintenance via semi-conservative replication (GO:0032201)3.36789694
76mitotic cytokinesis (GO:0000281)3.34946476
77spindle checkpoint (GO:0031577)3.34379684
78spindle organization (GO:0007051)3.32738353
79glucocorticoid receptor signaling pathway (GO:0042921)3.32640542
80nucleosome organization (GO:0034728)3.31425605
81regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.29415825
82telomere maintenance via recombination (GO:0000722)3.29085243
83nucleotide-excision repair, DNA gap filling (GO:0006297)3.28769443
84spindle assembly checkpoint (GO:0071173)3.26144705
85negative regulation of DNA-dependent DNA replication (GO:2000104)3.22666863
86pre-miRNA processing (GO:0031054)3.22056867
87ATP-dependent chromatin remodeling (GO:0043044)3.20547631
88negative regulation of mRNA processing (GO:0050686)3.17587544
89regulation of sister chromatid segregation (GO:0033045)3.17314561
90regulation of mitotic sister chromatid separation (GO:0010965)3.17314561
91regulation of mitotic sister chromatid segregation (GO:0033047)3.17314561
92histone exchange (GO:0043486)3.16816444
93mitotic spindle checkpoint (GO:0071174)3.16522003
94regulation of centrosome duplication (GO:0010824)3.16433011
95negative regulation of DNA repair (GO:0045738)3.15974613
96regulation of translational fidelity (GO:0006450)3.15059431
97establishment of integrated proviral latency (GO:0075713)3.13965501
98negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.12296499
99DNA damage response, signal transduction resulting in transcription (GO:0042772)3.12258335
100postreplication repair (GO:0006301)3.10477793
101sister chromatid cohesion (GO:0007062)3.08566105
102mitotic cell cycle (GO:0000278)3.07044117
103positive regulation of histone H3-K4 methylation (GO:0051571)3.06877222
104mRNA stabilization (GO:0048255)3.06565969
105RNA stabilization (GO:0043489)3.06565969
106positive regulation of cell cycle checkpoint (GO:1901978)3.05260962
107negative regulation of chromosome segregation (GO:0051985)3.05200724
108spindle assembly (GO:0051225)3.04601415
109spindle assembly involved in mitosis (GO:0090307)3.02133605
110establishment of mitotic spindle localization (GO:0040001)3.01040334
111mitotic DNA integrity checkpoint (GO:0044774)3.00584159
112regulation of DNA-dependent DNA replication (GO:0090329)2.99259696
113negative regulation of mitotic sister chromatid separation (GO:2000816)2.99051595
114negative regulation of mitotic sister chromatid segregation (GO:0033048)2.99051595
115negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.99051595
116negative regulation of sister chromatid segregation (GO:0033046)2.99051595
117histone phosphorylation (GO:0016572)2.98613843
118mitotic spindle assembly checkpoint (GO:0007094)2.98423095
119erythrocyte maturation (GO:0043249)2.97872180
120DNA synthesis involved in DNA repair (GO:0000731)2.97121167
121nuclear envelope organization (GO:0006998)2.94443288
122protein-DNA complex subunit organization (GO:0071824)2.93312146
123regulation of nucleobase-containing compound transport (GO:0032239)2.93188552
124protein-DNA complex assembly (GO:0065004)2.92469165

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* FOXM1_23109430_ChIP-Seq_U2OS_Human7.93044532
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human5.10745392
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.24331547
4* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.09346177
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.63413751
6E2F1_21310950_ChIP-Seq_MCF-7_Human2.73471767
7AR_21909140_ChIP-Seq_LNCAP_Human2.60645035
8HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.56219189
9* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.55461865
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.53813243
11MYC_22102868_ChIP-Seq_BL_Human2.53229671
12* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.32044401
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.05582617
14E2F7_22180533_ChIP-Seq_HELA_Human12.1036629
15MYC_18555785_ChIP-Seq_MESCs_Mouse1.96096616
16MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.82168747
17VDR_21846776_ChIP-Seq_THP-1_Human1.76517671
18TP63_19390658_ChIP-ChIP_HaCaT_Human1.71473228
19CIITA_25753668_ChIP-Seq_RAJI_Human1.67699566
20NELFA_20434984_ChIP-Seq_ESCs_Mouse1.60937212
21ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.59794758
22THAP11_20581084_ChIP-Seq_MESCs_Mouse1.59076008
23KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.57143817
24MYC_19030024_ChIP-ChIP_MESCs_Mouse1.55541049
25SCL_19346495_ChIP-Seq_HPC-7_Human1.51240480
26DCP1A_22483619_ChIP-Seq_HELA_Human1.49346297
27SALL1_21062744_ChIP-ChIP_HESCs_Human1.48341263
28TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.46962763
29MYC_19079543_ChIP-ChIP_MESCs_Mouse1.45697664
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.41933006
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.39350721
32FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.36460968
33HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.34293974
34CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.33854985
35SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.33769693
36STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.33084812
37MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.31327599
38TCF7_22412390_ChIP-Seq_EML_Mouse1.27577766
39* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.27260067
40KDM5A_27292631_Chip-Seq_BREAST_Human1.26794106
41ELK1_19687146_ChIP-ChIP_HELA_Human1.25706057
42MYCN_18555785_ChIP-Seq_MESCs_Mouse1.24569464
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.24503920
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.23811509
45XRN2_22483619_ChIP-Seq_HELA_Human1.20991281
46VDR_23849224_ChIP-Seq_CD4+_Human1.18936236
47MYB_26560356_Chip-Seq_TH2_Human1.18537842
48YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.18186069
49PADI4_21655091_ChIP-ChIP_MCF-7_Human1.17771060
50BRD4_27068464_Chip-Seq_AML-cells_Mouse1.17614363
51UTX_26944678_Chip-Seq_JUKART_Human1.17613229
52ESR1_15608294_ChIP-ChIP_MCF-7_Human1.16538845
53MAF_26560356_Chip-Seq_TH1_Human1.15311538
54RBPJ_22232070_ChIP-Seq_NCS_Mouse1.15143122
55SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.15120862
56MYB_26560356_Chip-Seq_TH1_Human1.14589022
57ETS1_20019798_ChIP-Seq_JURKAT_Human1.13402208
58FOXP3_21729870_ChIP-Seq_TREG_Human1.13242912
59E2F1_18555785_ChIP-Seq_MESCs_Mouse1.13084687
60GABP_19822575_ChIP-Seq_HepG2_Human1.12521193
61* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11649333
62PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10902340
63KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.10228162
64* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.09318218
65ZNF263_19887448_ChIP-Seq_K562_Human1.08019748
66TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06209649
67FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.05719002
68TP63_17297297_ChIP-ChIP_HaCaT_Human1.05455721
69IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.04526990
70VDR_24763502_ChIP-Seq_THP-1_Human1.03690885
71ERG_20887958_ChIP-Seq_HPC-7_Mouse1.02495615
72JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.01785189
73MYC_18358816_ChIP-ChIP_MESCs_Mouse0.99894649
74PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.99114730
75TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.98994716
76CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.98089618
77ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.97791424
78PKCTHETA_26484144_Chip-Seq_BREAST_Human0.97555583
79EST1_17652178_ChIP-ChIP_JURKAT_Human0.96050794
80CREB1_15753290_ChIP-ChIP_HEK293T_Human0.94274626
81KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.94064754
82SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.93515214
83CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.93270472
84GATA1_22025678_ChIP-Seq_K562_Human0.92044831
85CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.90977173
86GATA1_22383799_ChIP-Seq_G1ME_Mouse0.90902203
87ZFX_18555785_ChIP-Seq_MESCs_Mouse0.90444036
88POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.90427853
89SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.90197812
90FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.90151049
91GATA1_19941826_ChIP-Seq_K562_Human0.89366242
92RUNX1_22412390_ChIP-Seq_EML_Mouse0.89321300
93TFEB_21752829_ChIP-Seq_HELA_Human0.88592148
94ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.88192574
95ELF1_17652178_ChIP-ChIP_JURKAT_Human0.87849960
96NANOG_18555785_ChIP-Seq_MESCs_Mouse0.87596232
97DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.87442691
98TTF2_22483619_ChIP-Seq_HELA_Human0.87239643
99CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.87003609
100SOX2_16153702_ChIP-ChIP_HESCs_Human0.86723699
101* SPI1_23547873_ChIP-Seq_NB4_Human0.86698252
102STAT4_19710469_ChIP-ChIP_TH1__Mouse0.85334389
103NANOG_21062744_ChIP-ChIP_HESCs_Human0.84925141
104STAT3_1855785_ChIP-Seq_MESCs_Mouse0.84205745
105CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.84036095
106NCOR1_26117541_ChIP-Seq_K562_Human0.83488296
107STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.83208631
108HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.83166656
109GATA2_22383799_ChIP-Seq_G1ME_Mouse0.82747569
110KDM2B_26808549_Chip-Seq_DND41_Human0.82585145
111GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.81715516
112KLF4_18555785_ChIP-Seq_MESCs_Mouse0.81377687
113* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.81003250
114CHD1_26751641_Chip-Seq_LNCaP_Human0.80753023
115RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.80352568
116* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.80294707
117SOX17_20123909_ChIP-Seq_XEN_Mouse0.79525138
118SOX2_18555785_ChIP-Seq_MESCs_Mouse0.79284962
119TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.78854428
120* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.78711810
121TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.77402334
122* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.77035027
123KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.76835702
124* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.73762600
125POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.72121840
126POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.72034379
127* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.69613988
128SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.69551599
129ATF3_27146783_Chip-Seq_COLON_Human0.68624393
130DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.68273182
131UBF1/2_26484160_Chip-Seq_HMECs_Human0.68086429
132KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.68028959

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.39704323
2MP0003111_abnormal_nucleus_morphology4.01145468
3MP0003693_abnormal_embryo_hatching3.61515220
4MP0008057_abnormal_DNA_replication3.58488301
5MP0003077_abnormal_cell_cycle3.45114639
6MP0010307_abnormal_tumor_latency2.89690659
7MP0002396_abnormal_hematopoietic_system2.87175197
8MP0004957_abnormal_blastocyst_morpholog2.81587029
9MP0005076_abnormal_cell_differentiation2.65849093
10MP0010352_gastrointestinal_tract_polyps2.53113820
11MP0003656_abnormal_erythrocyte_physiolo2.52208030
12MP0000569_abnormal_digit_pigmentation2.45068654
13MP0004808_abnormal_hematopoietic_stem2.24709505
14MP0000350_abnormal_cell_proliferation2.07798073
15MP0009697_abnormal_copulation2.03590007
16MP0009278_abnormal_bone_marrow1.98273291
17MP0008058_abnormal_DNA_repair1.97741380
18MP0001730_embryonic_growth_arrest1.96719889
19MP0004147_increased_porphyrin_level1.96255869
20MP0003705_abnormal_hypodermis_morpholog1.95453095
21MP0008007_abnormal_cellular_replicative1.93236495
22MP0003121_genomic_imprinting1.91080438
23MP0008877_abnormal_DNA_methylation1.81303500
24MP0005397_hematopoietic_system_phenotyp1.80649961
25MP0001545_abnormal_hematopoietic_system1.80649961
26MP0004185_abnormal_adipocyte_glucose1.80582441
27MP0008932_abnormal_embryonic_tissue1.71409494
28MP0003300_gastrointestinal_ulcer1.65861041
29MP0001672_abnormal_embryogenesis/_devel1.65786210
30MP0005380_embryogenesis_phenotype1.65786210
31MP0004197_abnormal_fetal_growth/weight/1.62191500
32MP0003984_embryonic_growth_retardation1.57671377
33MP0000490_abnormal_crypts_of1.57352751
34MP0001697_abnormal_embryo_size1.57271031
35MP0000703_abnormal_thymus_morphology1.54847554
36MP0002088_abnormal_embryonic_growth/wei1.54756916
37MP0003123_paternal_imprinting1.53719624
38MP0002398_abnormal_bone_marrow1.52609011
39MP0006054_spinal_hemorrhage1.52505173
40MP0002086_abnormal_extraembryonic_tissu1.52105342
41MP0002166_altered_tumor_susceptibility1.50860824
42MP0003787_abnormal_imprinting1.47917252
43MP0002084_abnormal_developmental_patter1.45495226
44MP0002019_abnormal_tumor_incidence1.37935233
45MP0004233_abnormal_muscle_weight1.37743845
46MP0002085_abnormal_embryonic_tissue1.37302139
47MP0002080_prenatal_lethality1.36430638
48MP0001346_abnormal_lacrimal_gland1.31527481
49MP0002722_abnormal_immune_system1.30401922
50MP0003567_abnormal_fetal_cardiomyocyte1.29655588
51MP0000313_abnormal_cell_death1.27366114
52MP0000383_abnormal_hair_follicle1.25358947
53MP0005623_abnormal_meninges_morphology1.23959271
54MP0002006_tumorigenesis1.22426376
55MP0000689_abnormal_spleen_morphology1.20487566
56MP0009703_decreased_birth_body1.16666314
57MP0003566_abnormal_cell_adhesion1.13854257
58MP0003890_abnormal_embryonic-extraembry1.12136992
59MP0000733_abnormal_muscle_development1.11615655
60MP0001286_abnormal_eye_development1.09021415
61MP0003763_abnormal_thymus_physiology1.08446978
62MP0002095_abnormal_skin_pigmentation1.07617201
63MP0010678_abnormal_skin_adnexa1.06621866
64MP0002009_preneoplasia1.05625256
65MP0001800_abnormal_humoral_immune1.04639200
66MP0003303_peritoneal_inflammation1.03636806
67MP0002429_abnormal_blood_cell1.02085324
68MP0009672_abnormal_birth_weight1.01430836
69MP0003943_abnormal_hepatobiliary_system1.00656705
70MP0000685_abnormal_immune_system0.99727941
71MP0002877_abnormal_melanocyte_morpholog0.99688480
72MP0000716_abnormal_immune_system0.93949523
73MP0005409_darkened_coat_color0.93311603
74MP0009053_abnormal_anal_canal0.92359255
75MP0001915_intracranial_hemorrhage0.88206276
76MP0003385_abnormal_body_wall0.88100936
77MP0005621_abnormal_cell_physiology0.87650339
78MP0003950_abnormal_plasma_membrane0.86559010
79MP0002925_abnormal_cardiovascular_devel0.86260579
80MP0003861_abnormal_nervous_system0.86186855
81MP0001661_extended_life_span0.85784185
82MP0001293_anophthalmia0.85610560
83MP0010234_abnormal_vibrissa_follicle0.85322646
84MP0003937_abnormal_limbs/digits/tail_de0.83486498
85MP0003786_premature_aging0.83265540
86MP0002452_abnormal_antigen_presenting0.82887815
87MP0005501_abnormal_skin_physiology0.80854127
88MP0002420_abnormal_adaptive_immunity0.80520505
89MP0002092_abnormal_eye_morphology0.79812132
90MP0006292_abnormal_olfactory_placode0.79553497
91MP0003935_abnormal_craniofacial_develop0.79057811
92MP0001348_abnormal_lacrimal_gland0.79015663
93MP0002111_abnormal_tail_morphology0.78833231
94MP0001819_abnormal_immune_cell0.78603212
95MP0008770_decreased_survivor_rate0.78404222
96MP0004264_abnormal_extraembryonic_tissu0.77898703
97MP0005023_abnormal_wound_healing0.77491112
98MP0005451_abnormal_body_composition0.77089564
99MP0005384_cellular_phenotype0.76956177
100MP0004947_skin_inflammation0.76920575
101MP0009333_abnormal_splenocyte_physiolog0.76204514
102MP0001849_ear_inflammation0.75848982
103MP0000428_abnormal_craniofacial_morphol0.75226515
104MP0010030_abnormal_orbit_morphology0.74606452
105MP0002970_abnormal_white_adipose0.74227577
106MP0005174_abnormal_tail_pigmentation0.74081266
107MP0005187_abnormal_penis_morphology0.74026088
108MP0003115_abnormal_respiratory_system0.73054811
109MP0000432_abnormal_head_morphology0.72779844
110MP0002249_abnormal_larynx_morphology0.72730453
111MP0002405_respiratory_system_inflammati0.72462553
112MP0005257_abnormal_intraocular_pressure0.72231899
113MP0000537_abnormal_urethra_morphology0.71350308
114MP0003091_abnormal_cell_migration0.70371319
115MP0003755_abnormal_palate_morphology0.70133174
116MP0002210_abnormal_sex_determination0.69945591
117MP0003448_altered_tumor_morphology0.69892952
118MP0002114_abnormal_axial_skeleton0.69768139
119MP0000627_abnormal_mammary_gland0.69411141
120MP0003942_abnormal_urinary_system0.68731569
121MP0003718_maternal_effect0.68395987
122MP0000266_abnormal_heart_morphology0.68167379
123MP0005671_abnormal_response_to0.67645099
124MP0000377_abnormal_hair_follicle0.66957161
125MP0002697_abnormal_eye_size0.66591853
126MP0000003_abnormal_adipose_tissue0.66562282
127MP0009931_abnormal_skin_appearance0.65462205
128MP0003315_abnormal_perineum_morphology0.65400813
129MP0008961_abnormal_basal_metabolism0.65069111
130MP0000358_abnormal_cell_content/0.65023578
131MP0000534_abnormal_ureter_morphology0.64590192
132MP0002081_perinatal_lethality0.63624150
133MP0002060_abnormal_skin_morphology0.63161134
134MP0002098_abnormal_vibrissa_morphology0.63145714
135MP0001929_abnormal_gametogenesis0.61658402
136MP0003941_abnormal_skin_development0.61295990
137MP0000566_synostosis0.59379574
138MP0000762_abnormal_tongue_morphology0.58729666
139MP0003453_abnormal_keratinocyte_physiol0.58615615

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)4.96975647
2Chromsome breakage (HP:0040012)3.85083887
3Poikilocytosis (HP:0004447)3.82073707
4Abnormality of the fingertips (HP:0001211)3.72369744
5Short 4th metacarpal (HP:0010044)3.62524135
6Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.62524135
7Hypochromic microcytic anemia (HP:0004840)3.60522701
8Increased nuchal translucency (HP:0010880)3.49293912
9Chromosomal breakage induced by crosslinking agents (HP:0003221)3.38676751
10Abnormality of chromosome stability (HP:0003220)3.19088882
11Long eyelashes (HP:0000527)2.93987884
12Ectopic kidney (HP:0000086)2.90884859
13Abnormality of the heme biosynthetic pathway (HP:0010472)2.87487762
14Embryonal renal neoplasm (HP:0011794)2.77683783
15Proximal placement of thumb (HP:0009623)2.76960702
16Deviation of the thumb (HP:0009603)2.71086111
17Prominent nose (HP:0000448)2.65666076
18High anterior hairline (HP:0009890)2.62981095
19Impulsivity (HP:0100710)2.61863953
20Overlapping toe (HP:0001845)2.56784029
21High pitched voice (HP:0001620)2.55064006
22Abnormality of the 4th metacarpal (HP:0010012)2.52131249
23Deep philtrum (HP:0002002)2.45135350
2411 pairs of ribs (HP:0000878)2.44964776
25Missing ribs (HP:0000921)2.42730153
26Acanthocytosis (HP:0001927)2.41528576
27Truncal obesity (HP:0001956)2.38865372
28Myelodysplasia (HP:0002863)2.36217828
29Heterotopia (HP:0002282)2.32129072
30Macroorchidism (HP:0000053)2.31276754
31Cutis marmorata (HP:0000965)2.29785384
32Cafe-au-lait spot (HP:0000957)2.29384889
33Aplasia/Hypoplasia of the uvula (HP:0010293)2.28590919
34Small intestinal stenosis (HP:0012848)2.25263408
35Duodenal stenosis (HP:0100867)2.25263408
36Abnormality of the preputium (HP:0100587)2.25110977
37Meckel diverticulum (HP:0002245)2.21988545
38Medulloblastoma (HP:0002885)2.17002535
39Cellulitis (HP:0100658)2.15682896
40Obsessive-compulsive behavior (HP:0000722)2.14952838
41Selective tooth agenesis (HP:0001592)2.13931021
42Absent radius (HP:0003974)2.13792424
43Basal cell carcinoma (HP:0002671)2.12045332
44Abnormality of the distal phalanx of the thumb (HP:0009617)2.10020184
45Broad face (HP:0000283)2.09986364
46Acute myeloid leukemia (HP:0004808)2.09592390
47Abnormality of the phalanges of the hallux (HP:0010057)2.09443491
48Insomnia (HP:0100785)2.09323237
49Abnormality of the carotid arteries (HP:0005344)2.09223607
50Abnormality of the ileum (HP:0001549)2.09216923
51Abnormality of chromosome segregation (HP:0002916)2.08778566
52Abnormality of the calcaneus (HP:0008364)2.08758406
53Hyperacusis (HP:0010780)2.06122802
54Short thumb (HP:0009778)2.03901371
55Abnormal number of incisors (HP:0011064)2.03175188
56Ependymoma (HP:0002888)2.02539069
57Absent frontal sinuses (HP:0002688)2.01171792
58Embryonal neoplasm (HP:0002898)2.01111565
59Ulnar bowing (HP:0003031)1.99520013
60Recurrent viral infections (HP:0004429)1.98768533
61Birth length less than 3rd percentile (HP:0003561)1.98702875
62Blepharitis (HP:0000498)1.98609867
63Duplication of thumb phalanx (HP:0009942)1.98488541
64Facial hemangioma (HP:0000329)1.97721970
65Trigonocephaly (HP:0000243)1.97697125
66Hypochromic anemia (HP:0001931)1.97676452
67Reticulocytosis (HP:0001923)1.97510902
68Choanal atresia (HP:0000453)1.97370469
69B lymphocytopenia (HP:0010976)1.97179881
70Abnormality of B cell number (HP:0010975)1.97179881
71Rhabdomyosarcoma (HP:0002859)1.96637551
72Abnormality of reticulocytes (HP:0004312)1.95978749
73Aplasia involving forearm bones (HP:0009822)1.95924091
74Absent forearm bone (HP:0003953)1.95924091
75Atresia of the external auditory canal (HP:0000413)1.95659913
76Patellar aplasia (HP:0006443)1.94857239
77Low anterior hairline (HP:0000294)1.94712927
78Poikiloderma (HP:0001029)1.94111024
79Reticulocytopenia (HP:0001896)1.93254922
80Abnormal lung lobation (HP:0002101)1.92834377
81Sandal gap (HP:0001852)1.92343528
82Vertebral arch anomaly (HP:0008438)1.91730928
83Thyroiditis (HP:0100646)1.91696591
84Septate vagina (HP:0001153)1.90814768
85Hypopigmentation of the fundus (HP:0007894)1.89591675
86Sloping forehead (HP:0000340)1.86540575
87T lymphocytopenia (HP:0005403)1.86419269
88Overriding aorta (HP:0002623)1.85026777
89Elfin facies (HP:0004428)1.84836101
90Arteriovenous malformation (HP:0100026)1.84732751
91Abnormality of cochlea (HP:0000375)1.84690798
92Broad palm (HP:0001169)1.84345326
93Limited elbow extension (HP:0001377)1.84210035
94Acute lymphatic leukemia (HP:0006721)1.82346500
95Deep palmar crease (HP:0006191)1.82000912
96Progressive muscle weakness (HP:0003323)1.81688642
97Gastrointestinal carcinoma (HP:0002672)1.80878266
98Malignant gastrointestinal tract tumors (HP:0006749)1.80878266
99Increased density of long bones (HP:0006392)1.80547917
100Multiple enchondromatosis (HP:0005701)1.80342075
101Abnormal foot bone ossification (HP:0010675)1.79598145
102Colon cancer (HP:0003003)1.79309564
103Aplasia/Hypoplasia of the sacrum (HP:0008517)1.78954160
104Abnormality of the duodenum (HP:0002246)1.77748893
105Progressive external ophthalmoplegia (HP:0000590)1.77723069
106Aplasia/Hypoplasia of the patella (HP:0006498)1.77520048
107Verrucae (HP:0200043)1.76919968
108Papilloma (HP:0012740)1.76919968
109Asymmetry of the thorax (HP:0001555)1.76280354
110Astrocytoma (HP:0009592)1.75906427
111Abnormality of the astrocytes (HP:0100707)1.75906427
112Lip pit (HP:0100267)1.75655405
113Renovascular hypertension (HP:0100817)1.75321737
114Microtia (HP:0008551)1.75147869
115Cutaneous melanoma (HP:0012056)1.74772695
116Narrow palate (HP:0000189)1.74305755
117Skull defect (HP:0001362)1.74283570
118Dislocated radial head (HP:0003083)1.73745816
119Breast hypoplasia (HP:0003187)1.71106503
120Broad thumb (HP:0011304)1.70832866
121Aplasia/Hypoplasia of the sternum (HP:0006714)1.70261757
122Ankyloglossia (HP:0010296)1.69966683
123Flared metaphyses (HP:0003015)1.69882453
124Clubbing of toes (HP:0100760)1.69874997
125Radioulnar synostosis (HP:0002974)1.69106754
126Transitional cell carcinoma of the bladder (HP:0006740)1.68488557
127Termporal pattern (HP:0011008)1.68248631
128Insidious onset (HP:0003587)1.68248631
129Squamous cell carcinoma (HP:0002860)1.68236108
130IgM deficiency (HP:0002850)1.68196093
131Urethral obstruction (HP:0000796)1.67923968
132Renal duplication (HP:0000075)1.67842420
133Skin tags (HP:0010609)1.67314766
134Abnormality of T cell number (HP:0011839)1.67201900
135Broad distal phalanx of finger (HP:0009836)1.66977600
136Neoplasm of striated muscle (HP:0009728)1.66638895
137Short middle phalanx of the 5th finger (HP:0004220)1.65440314
138Cortical dysplasia (HP:0002539)1.65393387
139Duplicated collecting system (HP:0000081)1.65353271
140Long clavicles (HP:0000890)1.62716241
141Neoplasm of the oral cavity (HP:0100649)1.62595981
142Nephroblastoma (Wilms tumor) (HP:0002667)1.62577117
143Abnormality of DNA repair (HP:0003254)1.60868282

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.18395849
2CDK124.67906439
3NEK23.55946341
4SMG12.82598151
5MAP3K102.64388472
6STK42.54751473
7EEF2K2.54216818
8TLK12.37675796
9BRD42.26292206
10WEE12.10670002
11TTK2.01162863
12STK102.00237720
13CDK61.88934930
14CDK41.84320168
15EIF2AK11.81230775
16ATR1.80191216
17BUB11.75315374
18* AURKB1.74092691
19PBK1.71975001
20TAF11.69057494
21PKN21.67948500
22CHEK21.60264424
23ZAK1.59663883
24BRSK21.58828944
25MST1R1.54255014
26CAMK1D1.53726346
27PLK11.53146548
28MAP3K81.52936669
29NEK11.42755867
30STK31.42072364
31SRPK11.38945082
32MAP4K11.38913742
33SCYL21.36794225
34PNCK1.33825044
35CDK81.32806577
36RPS6KB21.29280952
37* CHEK11.28534136
38MELK1.28297972
39MKNK11.25655708
40ATM1.24458046
41BRSK11.24205297
42CDK91.20473419
43PLK31.19842381
44PIM11.18770572
45PLK41.18727109
46TRIB31.15326739
47CAMK1G1.14139117
48CDK71.11818360
49TTN1.09732516
50VRK21.09005881
51RPS6KA41.07818704
52PRPF4B1.05650250
53VRK11.01708090
54LATS10.96068405
55TRPM70.95639241
56* CDK20.93772578
57DYRK30.92788896
58MTOR0.92416407
59RPS6KA50.89832062
60PASK0.88720286
61MKNK20.88027103
62GRK60.83074420
63* CDK10.82587988
64CLK10.79735366
65ACVR1B0.78863236
66EIF2AK20.77350841
67IRAK30.75487481
68SIK10.73557524
69LRRK20.72168340
70SIK20.69192671
71BRAF0.68487271
72LATS20.68235816
73NME20.67282759
74EPHA20.65928359
75FGFR30.64674337
76AURKA0.63341892
77PTK60.62538430
78MET0.61940499
79ALK0.61008815
80CCNB10.57902070
81CSF1R0.57626515
82CSNK1D0.56611699
83PRKDC0.53932342
84BTK0.52528710
85DYRK1B0.51777468
86EIF2AK30.51212991
87MARK30.51112803
88* MAPK140.50456355
89JAK30.49865213
90CDK150.48733251
91CHUK0.48496383
92CDK11A0.47852401
93MAPK110.47521201
94CDK30.46658949
95CDK180.46631492
96PAK40.45606112
97FGFR40.45082353
98TGFBR10.44785436
99SYK0.44313157
100ERBB20.43889093
101NUAK10.43802481
102ERBB40.43354443
103TESK20.41739628
104WNK10.41391868
105MAP3K90.40667737
106AKT10.40448564
107FLT30.40057057
108TSSK60.37307639
109PDGFRB0.36988176
110PTK20.36871251
111NEK90.36626812
112FGFR10.35745243
113MAPK10.35161592
114AKT20.34649614
115CSNK1E0.34230400
116CDK140.33219789
117MAPK100.31280347
118DMPK0.30871946
119FGFR20.30823480
120RIPK10.30135608
121* GSK3B0.29538622
122PDGFRA0.28934370
123LCK0.28589141
124HIPK20.27926392
125MAP2K30.27852112
126ITK0.27766207
127PAK20.27088502
128ICK0.26823267
129CSNK2A20.26198794
130PRKCI0.22330212
131KSR10.20750221
132RAF10.20404671

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.95284354
2Systemic lupus erythematosus_Homo sapiens_hsa053223.82905401
3Cell cycle_Homo sapiens_hsa041103.39501422
4Mismatch repair_Homo sapiens_hsa034303.11248369
5Base excision repair_Homo sapiens_hsa034102.44908266
6Non-homologous end-joining_Homo sapiens_hsa034502.43479262
7Fanconi anemia pathway_Homo sapiens_hsa034602.36968998
8Homologous recombination_Homo sapiens_hsa034402.36741932
9RNA transport_Homo sapiens_hsa030132.18655942
10Spliceosome_Homo sapiens_hsa030402.16848458
11Viral carcinogenesis_Homo sapiens_hsa052032.04182150
12Alcoholism_Homo sapiens_hsa050341.98891634
13One carbon pool by folate_Homo sapiens_hsa006701.86780538
14mRNA surveillance pathway_Homo sapiens_hsa030151.83408403
15Nucleotide excision repair_Homo sapiens_hsa034201.83154996
16p53 signaling pathway_Homo sapiens_hsa041151.69976620
17MicroRNAs in cancer_Homo sapiens_hsa052061.64837917
18Chronic myeloid leukemia_Homo sapiens_hsa052201.60669634
19Transcriptional misregulation in cancer_Homo sapiens_hsa052021.49194902
20Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.49113965
21Small cell lung cancer_Homo sapiens_hsa052221.48383752
22Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.47144802
23Primary immunodeficiency_Homo sapiens_hsa053401.45511543
24Herpes simplex infection_Homo sapiens_hsa051681.37265870
25Lysine degradation_Homo sapiens_hsa003101.34954835
26HTLV-I infection_Homo sapiens_hsa051661.30305424
27RNA degradation_Homo sapiens_hsa030181.29875041
28B cell receptor signaling pathway_Homo sapiens_hsa046621.25275164
29Non-small cell lung cancer_Homo sapiens_hsa052231.25161580
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.19938189
31Antigen processing and presentation_Homo sapiens_hsa046121.19267182
32Oocyte meiosis_Homo sapiens_hsa041141.18849832
33Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.17824429
34Pancreatic cancer_Homo sapiens_hsa052121.16562864
35Hepatitis B_Homo sapiens_hsa051611.14934943
36Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.14709427
37NF-kappa B signaling pathway_Homo sapiens_hsa040641.08567707
38Biosynthesis of amino acids_Homo sapiens_hsa012301.06939812
39Epstein-Barr virus infection_Homo sapiens_hsa051691.06767877
40Prostate cancer_Homo sapiens_hsa052151.03910793
41Hematopoietic cell lineage_Homo sapiens_hsa046401.02435340
42Colorectal cancer_Homo sapiens_hsa052100.99831681
43Measles_Homo sapiens_hsa051620.98221798
44Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.98038605
45RNA polymerase_Homo sapiens_hsa030200.95101236
46Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.92190237
47Viral myocarditis_Homo sapiens_hsa054160.91610596
48Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.91522058
49Apoptosis_Homo sapiens_hsa042100.90498463
50mTOR signaling pathway_Homo sapiens_hsa041500.85278578
51Adherens junction_Homo sapiens_hsa045200.84334471
52Leishmaniasis_Homo sapiens_hsa051400.82038846
53NOD-like receptor signaling pathway_Homo sapiens_hsa046210.81299470
54Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.81163459
55Thyroid cancer_Homo sapiens_hsa052160.81118435
56FoxO signaling pathway_Homo sapiens_hsa040680.80164196
57Glioma_Homo sapiens_hsa052140.79855626
58Pyrimidine metabolism_Homo sapiens_hsa002400.77592221
59T cell receptor signaling pathway_Homo sapiens_hsa046600.75863282
60Pentose phosphate pathway_Homo sapiens_hsa000300.75731613
61Intestinal immune network for IgA production_Homo sapiens_hsa046720.75151734
62Proteoglycans in cancer_Homo sapiens_hsa052050.74347165
63Endometrial cancer_Homo sapiens_hsa052130.74324023
64Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.74215551
65Notch signaling pathway_Homo sapiens_hsa043300.73992089
66Influenza A_Homo sapiens_hsa051640.73566890
67Acute myeloid leukemia_Homo sapiens_hsa052210.73358273
68Bladder cancer_Homo sapiens_hsa052190.72069396
69Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.72045164
70Leukocyte transendothelial migration_Homo sapiens_hsa046700.71181816
71Basal transcription factors_Homo sapiens_hsa030220.68848825
72Thyroid hormone signaling pathway_Homo sapiens_hsa049190.68648084
73ErbB signaling pathway_Homo sapiens_hsa040120.68476206
74Osteoclast differentiation_Homo sapiens_hsa043800.67811765
75TGF-beta signaling pathway_Homo sapiens_hsa043500.66395161
76Platelet activation_Homo sapiens_hsa046110.64622322
77Toxoplasmosis_Homo sapiens_hsa051450.64599793
78Wnt signaling pathway_Homo sapiens_hsa043100.63386975
79Cysteine and methionine metabolism_Homo sapiens_hsa002700.62717992
80Pathways in cancer_Homo sapiens_hsa052000.61118874
81Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.60180688
82Dorso-ventral axis formation_Homo sapiens_hsa043200.58485888
83Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.56445876
84Purine metabolism_Homo sapiens_hsa002300.56405468
85Shigellosis_Homo sapiens_hsa051310.56253826
86Neurotrophin signaling pathway_Homo sapiens_hsa047220.56253291
87Basal cell carcinoma_Homo sapiens_hsa052170.55661206
88Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52778121
89AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.52768012
90Jak-STAT signaling pathway_Homo sapiens_hsa046300.50737208
91Sulfur relay system_Homo sapiens_hsa041220.50574812
92Central carbon metabolism in cancer_Homo sapiens_hsa052300.50187705
93Melanoma_Homo sapiens_hsa052180.49895330
94Malaria_Homo sapiens_hsa051440.49689216
95Carbon metabolism_Homo sapiens_hsa012000.49027271
96Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.48452151
97Focal adhesion_Homo sapiens_hsa045100.48257108
98HIF-1 signaling pathway_Homo sapiens_hsa040660.46803884
99Toll-like receptor signaling pathway_Homo sapiens_hsa046200.46672658
1002-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.46089196
101Legionellosis_Homo sapiens_hsa051340.45822013
102Ribosome_Homo sapiens_hsa030100.45673715
103TNF signaling pathway_Homo sapiens_hsa046680.45309963
104Regulation of actin cytoskeleton_Homo sapiens_hsa048100.44805614
105Hippo signaling pathway_Homo sapiens_hsa043900.44652288
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.43582868
107Renal cell carcinoma_Homo sapiens_hsa052110.43516513
108Prolactin signaling pathway_Homo sapiens_hsa049170.43374812
109RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.42910378
110N-Glycan biosynthesis_Homo sapiens_hsa005100.42659572
111Vitamin B6 metabolism_Homo sapiens_hsa007500.42018339
112Chemokine signaling pathway_Homo sapiens_hsa040620.41552304
113Hedgehog signaling pathway_Homo sapiens_hsa043400.41503675
114Insulin signaling pathway_Homo sapiens_hsa049100.41359731
115VEGF signaling pathway_Homo sapiens_hsa043700.40476609
116Proteasome_Homo sapiens_hsa030500.38998633
117AMPK signaling pathway_Homo sapiens_hsa041520.38724882
118Inositol phosphate metabolism_Homo sapiens_hsa005620.37911041
119Selenocompound metabolism_Homo sapiens_hsa004500.35805841
120Hepatitis C_Homo sapiens_hsa051600.35372723
121Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.34015655
122Fatty acid biosynthesis_Homo sapiens_hsa000610.32466267
123Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.30906598
124Fructose and mannose metabolism_Homo sapiens_hsa000510.30484356
125Phosphatidylinositol signaling system_Homo sapiens_hsa040700.28658402
126Pyruvate metabolism_Homo sapiens_hsa006200.27747574
127Melanogenesis_Homo sapiens_hsa049160.27721806
128Estrogen signaling pathway_Homo sapiens_hsa049150.27579069
129Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.27560205
130Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.27387240

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