MLANA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ketone body metabolic process (GO:1902224)8.71862871
2pigment biosynthetic process (GO:0046148)7.85745308
3melanocyte differentiation (GO:0030318)7.70849315
4vitamin A metabolic process (GO:0006776)7.57813129
5pigment cell differentiation (GO:0050931)7.06199313
6endosome to melanosome transport (GO:0035646)6.20546704
7endosome to pigment granule transport (GO:0043485)6.20546704
8melanosome organization (GO:0032438)6.19660442
9pigment metabolic process (GO:0042440)6.01065278
10pigment granule organization (GO:0048753)5.88192820
11regulation of endothelial cell chemotaxis (GO:2001026)5.33021681
12myotube differentiation (GO:0014902)4.94851415
13neuroepithelial cell differentiation (GO:0060563)4.94103193
14positive regulation of neuroblast proliferation (GO:0002052)4.70070809
15mesenchymal-epithelial cell signaling (GO:0060638)4.65810934
16negative regulation of hydrogen peroxide-induced cell death (GO:1903206)4.56436118
17pigmentation (GO:0043473)4.45946939
18enteric nervous system development (GO:0048484)4.43912088
19aromatic amino acid family metabolic process (GO:0009072)4.17266381
20short-chain fatty acid metabolic process (GO:0046459)4.16196847
21melanosome localization (GO:0032400)4.12917515
22negative regulation of response to reactive oxygen species (GO:1901032)4.12907921
23regulation of hydrogen peroxide-induced cell death (GO:1903205)4.12141179
24platelet dense granule organization (GO:0060155)4.10941684
25phenol-containing compound metabolic process (GO:0018958)4.08574311
26melanosome transport (GO:0032402)4.06645907
27regulation of branching involved in salivary gland morphogenesis (GO:0060693)4.00455669
28melanin biosynthetic process (GO:0042438)33.1129397
29melanin metabolic process (GO:0006582)30.0652546
30negative regulation of macroautophagy (GO:0016242)3.99775707
31pigment granule localization (GO:0051875)3.94600094
32establishment of melanosome localization (GO:0032401)3.86758941
33pigment granule transport (GO:0051904)3.86115728
34endothelial cell morphogenesis (GO:0001886)3.84189843
35establishment of pigment granule localization (GO:0051905)3.67986029
36proline transport (GO:0015824)3.52231722
37somatic stem cell division (GO:0048103)3.47188675
38regulation of neuroblast proliferation (GO:1902692)3.27650134
39regulation of integrin-mediated signaling pathway (GO:2001044)3.25314777
40antigen processing and presentation via MHC class Ib (GO:0002475)3.23746879
41nerve growth factor signaling pathway (GO:0038180)3.18795792
42mitotic G1 DNA damage checkpoint (GO:0031571)3.10377762
43semaphorin-plexin signaling pathway (GO:0071526)3.08631923
44regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.05246586
45cornea development in camera-type eye (GO:0061303)3.00200603
46secondary metabolite biosynthetic process (GO:0044550)27.5389117
47columnar/cuboidal epithelial cell differentiation (GO:0002065)2.99613087
48basement membrane organization (GO:0071711)2.91836586
49retinal metabolic process (GO:0042574)2.89520584
50regulation of protein sumoylation (GO:0033233)2.82903660
51peripheral nervous system development (GO:0007422)2.81187828
52keratinocyte development (GO:0003334)2.80614638
53muscle cell migration (GO:0014812)2.75071269
54sialylation (GO:0097503)2.74190980
55retinal rod cell development (GO:0046548)2.73954073
56intracellular pH reduction (GO:0051452)2.72498374
57barbed-end actin filament capping (GO:0051016)2.71036616
58mitotic G1/S transition checkpoint (GO:0044819)2.67772409
59calcium-mediated signaling using intracellular calcium source (GO:0035584)2.64983243
60fibroblast migration (GO:0010761)2.64100694
61G1 DNA damage checkpoint (GO:0044783)2.62498427
62inositol phosphate catabolic process (GO:0071545)2.60642928
63alanine transport (GO:0032328)2.55068840
64regulation of somitogenesis (GO:0014807)2.54632706
65cGMP-mediated signaling (GO:0019934)2.46736577
66bone remodeling (GO:0046849)2.46129878
67negative regulation of response to nutrient levels (GO:0032108)2.45171372
68negative regulation of response to extracellular stimulus (GO:0032105)2.45171372
69negative regulation of organelle assembly (GO:1902116)2.43989338
70fusion of sperm to egg plasma membrane (GO:0007342)2.43332204
71secretory granule organization (GO:0033363)2.42883502
72negative regulation of oxidative stress-induced cell death (GO:1903202)2.38068842
73dosage compensation (GO:0007549)2.37755560
74negative regulation of transcription by competitive promoter binding (GO:0010944)2.35604725
75positive regulation of neural precursor cell proliferation (GO:2000179)2.34602019
76pH reduction (GO:0045851)2.34189553
77regulation of response to reactive oxygen species (GO:1901031)2.31071958
78negative regulation of response to oxidative stress (GO:1902883)2.28051807
79negative regulation of cellular response to oxidative stress (GO:1900408)2.28051807
80stem cell division (GO:0017145)2.26120105
81negative regulation of interleukin-1 beta production (GO:0032691)2.25064062
82cellular response to reactive nitrogen species (GO:1902170)2.21688572
83cellular response to nitric oxide (GO:0071732)2.20356707
84regulation of centriole replication (GO:0046599)2.20253202
85long-chain fatty acid biosynthetic process (GO:0042759)2.18298800
86polyol catabolic process (GO:0046174)2.16870343
87vesicle localization (GO:0051648)2.16193250
88chondroitin sulfate catabolic process (GO:0030207)2.15558254
89neural crest cell migration (GO:0001755)2.12714779
90behavioral response to ethanol (GO:0048149)2.12390417
91negative regulation of fatty acid biosynthetic process (GO:0045717)2.11899874
92embryonic body morphogenesis (GO:0010172)2.11844339
93organic hydroxy compound biosynthetic process (GO:1901617)2.10008316
94detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.09941099
95cellular response to electrical stimulus (GO:0071257)2.08980292
96protein-chromophore linkage (GO:0018298)2.08733073
97acrosome reaction (GO:0007340)2.08398667
98Rap protein signal transduction (GO:0032486)2.08102386
99signal peptide processing (GO:0006465)2.03694408
100retinol metabolic process (GO:0042572)2.02703446
101response to methylmercury (GO:0051597)2.01566999
102antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.01259889
103tyrosine metabolic process (GO:0006570)13.8685651
104developmental pigmentation (GO:0048066)11.5924880
105phenol-containing compound biosynthetic process (GO:0046189)10.9407403
106secondary metabolic process (GO:0019748)10.7604073
107regulation of penile erection (GO:0060405)1.97866097
108regulation of superoxide anion generation (GO:0032928)1.93216156
109oligodendrocyte differentiation (GO:0048709)1.93177442
110plasma membrane fusion (GO:0045026)1.93037174
111negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)1.92861963
112establishment of nucleus localization (GO:0040023)1.92783222
113regulation of intracellular pH (GO:0051453)1.92388672
1144-hydroxyproline metabolic process (GO:0019471)1.92347201
115Rac protein signal transduction (GO:0016601)1.91601411
116response to nitric oxide (GO:0071731)1.91096838
117negative regulation of TOR signaling (GO:0032007)1.90616652
118negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)1.90557144
119folic acid-containing compound biosynthetic process (GO:0009396)1.90517465
120osteoclast differentiation (GO:0030316)1.87650769
121cranial nerve development (GO:0021545)1.87526450
122regulation of cellular pH (GO:0030641)1.87260047
123negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)1.86029166
124proteasome assembly (GO:0043248)1.85578610
125response to nerve growth factor (GO:1990089)1.83316790
126cellular response to nerve growth factor stimulus (GO:1990090)1.83316790
127mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)1.77629991
128autophagic vacuole fusion (GO:0000046)1.76511743
129positive regulation of receptor recycling (GO:0001921)1.75820987
130protein K6-linked ubiquitination (GO:0085020)1.75759889
131transcription elongation from RNA polymerase III promoter (GO:0006385)1.75548759
132termination of RNA polymerase III transcription (GO:0006386)1.75548759
133positive regulation of glucose transport (GO:0010828)1.75138644
134negative regulation of histone methylation (GO:0031061)1.74293211
135peptidyl-lysine dimethylation (GO:0018027)1.70433574
136myelin assembly (GO:0032288)1.69878591
137regulation of translational fidelity (GO:0006450)1.69098909
138negative regulation of fatty acid metabolic process (GO:0045922)1.67883087
139regulation of oxidative stress-induced cell death (GO:1903201)1.67181307
140regulation of apoptotic cell clearance (GO:2000425)1.66067573
141positive chemotaxis (GO:0050918)1.64165348
142regulation of early endosome to late endosome transport (GO:2000641)1.62719037
143glycolytic process (GO:0006096)1.62669056
144fat-soluble vitamin metabolic process (GO:0006775)1.61718819
145establishment of mitotic spindle orientation (GO:0000132)1.58630746
146regulation of histone H3-K9 methylation (GO:0051570)1.57706973
147glycoprotein catabolic process (GO:0006516)1.53009738
148centrosome duplication (GO:0051298)1.50900651
149placenta development (GO:0001890)1.50660967
150negative regulation of membrane potential (GO:0045837)1.50180360
151positive regulation of DNA-dependent DNA replication (GO:2000105)1.49973573
152positive regulation of osteoblast proliferation (GO:0033690)1.48601020
153regulation of cellular response to oxidative stress (GO:1900407)1.48367089
154inositol phosphate dephosphorylation (GO:0046855)1.48142333
155phosphorylated carbohydrate dephosphorylation (GO:0046838)1.48142333
156negative regulation of hormone biosynthetic process (GO:0032353)1.47968355
157negative regulation of hormone metabolic process (GO:0032351)1.47968355
158pyruvate metabolic process (GO:0006090)1.46569168
159cellular glucuronidation (GO:0052695)1.46289828
160dorsal/ventral axis specification (GO:0009950)1.44322683

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat8.04501052
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse6.76379112
3E2F7_22180533_ChIP-Seq_HELA_Human5.44713233
4GATA1_22025678_ChIP-Seq_K562_Human4.23699761
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.73252418
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.54359417
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.12029630
8RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.01811335
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.86922662
10HIF1A_21447827_ChIP-Seq_MCF-7_Human2.75334495
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.69186861
12ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.63085042
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.44873412
14JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.31435145
15CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.24851981
16SRF_21415370_ChIP-Seq_HL-1_Mouse2.22633091
17ESR1_15608294_ChIP-ChIP_MCF-7_Human2.22024703
18CDX2_19796622_ChIP-Seq_MESCs_Mouse2.12982513
19ZFP57_27257070_Chip-Seq_ESCs_Mouse2.11189785
20EST1_17652178_ChIP-ChIP_JURKAT_Human2.04959106
21POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.04242109
22RBPJ_22232070_ChIP-Seq_NCS_Mouse11.1250986
23EGR1_19032775_ChIP-ChIP_M12_Human1.96304746
24PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.89206667
25TFEB_21752829_ChIP-Seq_HELA_Human1.89196293
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.78714537
27PIAS1_25552417_ChIP-Seq_VCAP_Human1.78516070
28TP63_17297297_ChIP-ChIP_HaCaT_Human1.77905728
29P300_19829295_ChIP-Seq_ESCs_Human1.70633474
30ZNF263_19887448_ChIP-Seq_K562_Human1.65550930
31OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.64335931
32POU3F2_20337985_ChIP-ChIP_501MEL_Human1.63849856
33AR_21909140_ChIP-Seq_LNCAP_Human1.63840463
34NFE2_27457419_Chip-Seq_LIVER_Mouse1.63553585
35ESR1_20079471_ChIP-ChIP_T-47D_Human1.60527000
36SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.58282259
37* MITF_21258399_ChIP-Seq_MELANOMA_Human1.56338747
38ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.56144677
39MYC_18555785_ChIP-Seq_MESCs_Mouse1.53051218
40CLOCK_20551151_ChIP-Seq_293T_Human1.52840853
41AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.48075972
42MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.46273370
43EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.44851246
44CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.44797891
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44049201
46EZH2_27294783_Chip-Seq_NPCs_Mouse1.43365766
47TRIM28_21343339_ChIP-Seq_HEK293_Human1.42784730
48ETS1_20019798_ChIP-Seq_JURKAT_Human1.41495732
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.37201705
50CTCF_18555785_Chip-Seq_ESCs_Mouse1.36226330
51SMAD1_18555785_Chip-Seq_ESCs_Mouse1.35954899
52CTBP2_25329375_ChIP-Seq_LNCAP_Human1.29931794
53SUZ12_27294783_Chip-Seq_NPCs_Mouse1.29690484
54FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.29494782
55RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.28851383
56SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.28561997
57SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.28561997
58FOXM1_23109430_ChIP-Seq_U2OS_Human1.28319907
59TCF4_23295773_ChIP-Seq_U87_Human1.27721812
60FUS_26573619_Chip-Seq_HEK293_Human1.26726579
61MYC_18940864_ChIP-ChIP_HL60_Human1.25667926
62GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.24600079
63MYC_19079543_ChIP-ChIP_MESCs_Mouse1.24484783
64SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.24459201
65RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.23728686
66CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.23674146
67JUN_21703547_ChIP-Seq_K562_Human1.23145350
68AUTS2_25519132_ChIP-Seq_293T-REX_Human1.22033025
69AR_21572438_ChIP-Seq_LNCaP_Human1.21835510
70THAP11_20581084_ChIP-Seq_MESCs_Mouse1.20820502
71PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.20599742
72SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.19857929
73E2F1_21310950_ChIP-Seq_MCF-7_Human1.18579841
74MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.18299081
75BRD4_25478319_ChIP-Seq_HGPS_Human1.17433648
76ELK1_19687146_ChIP-ChIP_HELA_Human1.16975671
77TBX20_22328084_ChIP-Seq_HEART_Mouse1.16803854
78TBX20_22080862_ChIP-Seq_HEART_Mouse1.16803854
79SMAD3_21741376_ChIP-Seq_ESCs_Human1.16514204
80NMYC_18555785_Chip-Seq_ESCs_Mouse1.16469475
81HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.15478329
82ZNF274_21170338_ChIP-Seq_K562_Hela1.14683041
83OCT4_18555785_Chip-Seq_ESCs_Mouse1.14490078
84TAL1_26923725_Chip-Seq_HPCs_Mouse1.14345392
85STAT3_18555785_Chip-Seq_ESCs_Mouse1.14012397
86GATA3_20176728_ChIP-ChIP_TSCs_Mouse1.13814542
87ESRRB_18555785_Chip-Seq_ESCs_Mouse1.13512561
88KLF4_18555785_Chip-Seq_ESCs_Mouse1.12655725
89CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.11889225
90FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.11825593
91SALL1_21062744_ChIP-ChIP_HESCs_Human1.11292220
92TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.11060637
93TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10853306
94ZFX_18555785_Chip-Seq_ESCs_Mouse1.08771888
95PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.08147304
96PPAR_26484153_Chip-Seq_NCI-H1993_Human1.07926517
97IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.07560171
98P53_22387025_ChIP-Seq_ESCs_Mouse1.07455216
99SOX2_18555785_Chip-Seq_ESCs_Mouse1.06680957
100ETV2_25802403_ChIP-Seq_MESCs_Mouse1.06202527
101KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.06170870
102FOXP3_21729870_ChIP-Seq_TREG_Human1.05781455
103MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.05538032
104CRX_20693478_ChIP-Seq_RETINA_Mouse1.05244205
105ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.04788751
106CMYC_18555785_Chip-Seq_ESCs_Mouse1.04351636
107SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.04326046
108VDR_23849224_ChIP-Seq_CD4+_Human1.02943532
109NR3C1_21868756_ChIP-Seq_MCF10A_Human1.02031638
110SUZ12_18555785_Chip-Seq_ESCs_Mouse1.02003577
111FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.01840643
112SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.00770945
113P300_18555785_Chip-Seq_ESCs_Mouse1.00331147
114AR_25329375_ChIP-Seq_VCAP_Human1.00092541
115TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99090932
116PU1_27457419_Chip-Seq_LIVER_Mouse0.98998266
117SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.98935436
118* KAP1_22055183_ChIP-Seq_ESCs_Mouse0.98056083
119NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.98018866
120ATF3_27146783_Chip-Seq_COLON_Human0.97814564
121UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.96865354
122HOXB7_26014856_ChIP-Seq_BT474_Human0.96595428
123UBF1/2_26484160_Chip-Seq_HMECs_Human0.96443527
124PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.95572373
125PCGF2_27294783_Chip-Seq_ESCs_Mouse0.94715269
126GABP_19822575_ChIP-Seq_HepG2_Human0.94402025
127E2F1_18555785_Chip-Seq_ESCs_Mouse0.93758505
128ERG_20887958_ChIP-Seq_HPC-7_Mouse0.93391968
129ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.93204802
130CTNNB1_20460455_ChIP-Seq_HCT116_Human0.92909544
131NELFA_20434984_ChIP-Seq_ESCs_Mouse0.92667377
132P300_27058665_Chip-Seq_ZR-75-30cells_Human0.92636250
133E2F1_17053090_ChIP-ChIP_MCF-7_Human0.92343525
134EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.92098394
135* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.92045985
136FOXA1_21572438_ChIP-Seq_LNCaP_Human0.91912896
137GF1B_26923725_Chip-Seq_HPCs_Mouse0.91285012
138TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89934947
139IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.89934290
140CBP_20019798_ChIP-Seq_JUKART_Human0.89934290
141KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.89809351
142PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.89606858
143SOX2_21211035_ChIP-Seq_LN229_Gbm0.89178355
144STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.88982932
145SOX9_24532713_ChIP-Seq_HFSC_Mouse0.88289701
146YY1_21170310_ChIP-Seq_MESCs_Mouse0.88250578
147CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88105510
148TCF4_22108803_ChIP-Seq_LS180_Human0.87625785
149CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.87331196
150FOXO3_23340844_ChIP-Seq_DLD1_Human0.87233926
151STAT3_23295773_ChIP-Seq_U87_Human0.87202401
152FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.86760111
153ESR2_21235772_ChIP-Seq_MCF-7_Human0.86554808
154TP53_18474530_ChIP-ChIP_U2OS_Human0.85714950
155RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.85396996
156E2F4_17652178_ChIP-ChIP_JURKAT_Human0.79861307
157CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.79824233
158BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.79617422
159NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.77540219
160CTBP1_25329375_ChIP-Seq_LNCAP_Human0.77275490
161RARG_19884340_ChIP-ChIP_MEFs_Mouse0.76347136
162ISL1_27105846_Chip-Seq_CPCs_Mouse0.76309765
163KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.76143428
164PADI4_21655091_ChIP-ChIP_MCF-7_Human0.74070196
165TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.73368671
166CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.73272619
167GATA4_21415370_ChIP-Seq_HL-1_Mouse0.73250961
168PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.72957308
169STAT3_1855785_ChIP-Seq_MESCs_Mouse0.72802697
170WT1_19549856_ChIP-ChIP_CCG9911_Human0.72284964
171SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.71954929
172BRD4_27068464_Chip-Seq_AML-cells_Mouse0.70556219
173EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.70455677
174* CJUN_26792858_Chip-Seq_BT549_Human0.70450559
175SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.68635316
176POU5F1_16518401_ChIP-PET_MESCs_Mouse0.68038664
177PCGF2_27294783_Chip-Seq_NPCs_Mouse0.67778383
178NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.67055883
179FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.66950099
180SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.65941415
181BP1_19119308_ChIP-ChIP_Hs578T_Human0.65631611
182ETS1_22383799_ChIP-Seq_G1ME_Mouse0.65302586
183DNAJC2_21179169_ChIP-ChIP_NT2_Human0.65048721
184ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.64834196
185RUNX1_27514584_Chip-Seq_MCF-7_Human0.64563857

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005171_absent_coat_pigmentation8.99276252
2MP0003136_yellow_coat_color5.60582397
3MP0005408_hypopigmentation5.59755459
4MP0000371_diluted_coat_color4.42095781
5MP0005257_abnormal_intraocular_pressure4.21697275
6MP0004381_abnormal_hair_follicle3.99728732
7MP0002095_abnormal_skin_pigmentation3.27524801
8MP0002877_abnormal_melanocyte_morpholog3.27366950
9MP0000015_abnormal_ear_pigmentation3.15309900
10MP0005377_hearing/vestibular/ear_phenot2.99610396
11MP0003878_abnormal_ear_physiology2.99610396
12MP0001324_abnormal_eye_pigmentation2.81872961
13MP0002075_abnormal_coat/hair_pigmentati2.54613247
14MP0003011_delayed_dark_adaptation2.50697367
15MP0005075_abnormal_melanosome_morpholog2.45618283
16MP0002102_abnormal_ear_morphology2.34843788
17MP0001186_pigmentation_phenotype2.03561188
18MP0000372_irregular_coat_pigmentation10.7999709
19MP0005174_abnormal_tail_pigmentation1.91193575
20MP0000569_abnormal_digit_pigmentation1.73401818
21MP0005248_abnormal_Harderian_gland1.67843424
22MP0002938_white_spotting1.67224213
23MP0004885_abnormal_endolymph1.57034349
24MP0005197_abnormal_uvea_morphology1.31887056
25MP0002090_abnormal_vision1.26818019
26MP0002638_abnormal_pupillary_reflex1.24491113
27MP0005409_darkened_coat_color1.19719116
28MP0003705_abnormal_hypodermis_morpholog1.19329766
29MP0005253_abnormal_eye_physiology0.98758362
30MP0003806_abnormal_nucleotide_metabolis0.85839443
31MP0010234_abnormal_vibrissa_follicle0.84865986
32MP0010094_abnormal_chromosome_stability0.82527363
33MP0001293_anophthalmia0.73648258
34MP0000733_abnormal_muscle_development0.66133629
35MP0000367_abnormal_coat/_hair0.65901162
36MP0003453_abnormal_keratinocyte_physiol0.65402654
37MP0003646_muscle_fatigue0.64735396
38MP0002089_abnormal_postnatal_growth/wei0.62744402
39MP0002092_abnormal_eye_morphology0.60074814
40MP0005551_abnormal_eye_electrophysiolog0.59466030
41MP0005391_vision/eye_phenotype0.58983538
42MP0008260_abnormal_autophagy0.58560681
43MP0006054_spinal_hemorrhage0.56461829
44MP0000377_abnormal_hair_follicle0.53132808
45MP0002837_dystrophic_cardiac_calcinosis0.51087529
46MP0008438_abnormal_cutaneous_collagen0.49981258
47MP0000762_abnormal_tongue_morphology0.49448615
48MP0005058_abnormal_lysosome_morphology0.47453852
49MP0004084_abnormal_cardiac_muscle0.47212979
50MP0006138_congestive_heart_failure0.44077285
51MP0005193_abnormal_anterior_eye0.43971964
52MP0010307_abnormal_tumor_latency0.43878964
53MP0003566_abnormal_cell_adhesion0.42957308
54MP0005023_abnormal_wound_healing0.42458597
55MP0001485_abnormal_pinna_reflex0.39540786
56MP0001984_abnormal_olfaction0.37737890
57MP0002177_abnormal_outer_ear0.37706040
58MP0009697_abnormal_copulation0.35786017
59MP0001188_hyperpigmentation0.34875382
60MP0005623_abnormal_meninges_morphology0.33489140
61MP0000749_muscle_degeneration0.31471264
62MP0000920_abnormal_myelination0.30065129
63MP0003950_abnormal_plasma_membrane0.29462967
64MP0003567_abnormal_fetal_cardiomyocyte0.28238719
65MP0001849_ear_inflammation0.28020123
66MP0001851_eye_inflammation0.27698114
67MP0005275_abnormal_skin_tensile0.27151372
68MP0009840_abnormal_foam_cell0.25055206
69MP0003943_abnormal_hepatobiliary_system0.24667416
70MP0003111_abnormal_nucleus_morphology0.24587481
71MP0002751_abnormal_autonomic_nervous0.24376080
72MP0008770_decreased_survivor_rate0.23882257
73MP0010352_gastrointestinal_tract_polyps0.23468933
74MP0008569_lethality_at_weaning0.22065638
75MP0003186_abnormal_redox_activity0.21873696
76MP0000358_abnormal_cell_content/0.21697536
77MP0003091_abnormal_cell_migration0.21451843
78MP0001958_emphysema0.19771046
79MP0004233_abnormal_muscle_weight0.19742574
80MP0002822_catalepsy0.19705456
81MP0004197_abnormal_fetal_growth/weight/0.19429457
82MP0008932_abnormal_embryonic_tissue0.18882346
83MP0005503_abnormal_tendon_morphology0.17979855
84MP0004019_abnormal_vitamin_homeostasis0.17322663
85MP0003191_abnormal_cellular_cholesterol0.17135337
86MP0002697_abnormal_eye_size0.16397916
87MP0004272_abnormal_basement_membrane0.16015499
88MP0003634_abnormal_glial_cell0.15017589
89MP0005187_abnormal_penis_morphology0.14872582
90MP0010678_abnormal_skin_adnexa0.14721180
91MP0004147_increased_porphyrin_level0.13958485
92MP0004036_abnormal_muscle_relaxation0.13746428
93MP0005670_abnormal_white_adipose0.11170591
94MP0002060_abnormal_skin_morphology0.10995868
95MP0003385_abnormal_body_wall0.10544701
96MP0001963_abnormal_hearing_physiology0.10503150
97MP0005195_abnormal_posterior_eye0.10286575
98MP0002909_abnormal_adrenal_gland0.10074923
99MP0000427_abnormal_hair_cycle0.10054734
100MP0003632_abnormal_nervous_system0.09546682
101MP0000747_muscle_weakness0.09536570
102MP0004924_abnormal_behavior0.09301676
103MP0005386_behavior/neurological_phenoty0.09301676
104MP0008007_abnormal_cellular_replicative0.08787899
105MP0001270_distended_abdomen0.08726369
106MP0002269_muscular_atrophy0.08341354
107MP0004215_abnormal_myocardial_fiber0.07969369
108MP0000537_abnormal_urethra_morphology0.07835588
109MP0003937_abnormal_limbs/digits/tail_de0.07726111
110MP0003172_abnormal_lysosome_physiology0.07541056
111MP0003938_abnormal_ear_development0.06797698
112MP0000647_abnormal_sebaceous_gland0.06194346
113MP0004808_abnormal_hematopoietic_stem0.05645287
114MP0004087_abnormal_muscle_fiber0.05402635
115MP0010329_abnormal_lipoprotein_level0.05232386
116MP0000639_abnormal_adrenal_gland0.04881833
117MP0003077_abnormal_cell_cycle0.04423314
118MP0002752_abnormal_somatic_nervous0.04033112
119MP0001299_abnormal_eye_distance/0.03784856
120MP0009384_cardiac_valve_regurgitation0.03728551
121MP0005379_endocrine/exocrine_gland_phen0.03119211
122MP0001502_abnormal_circadian_rhythm0.02759064
123MP0003698_abnormal_male_reproductive0.02593822
124MP0009046_muscle_twitch0.02495108
125MP0002998_abnormal_bone_remodeling0.02467908
126MP0003119_abnormal_digestive_system0.02170487
127MP0009703_decreased_birth_body0.02165226
128MP0001730_embryonic_growth_arrest0.02126038
129MP0005384_cellular_phenotype0.02034054
130MP0002229_neurodegeneration0.01798753
131MP0001697_abnormal_embryo_size0.01696200
132MP0002557_abnormal_social/conspecific_i0.01606288
133MP0000026_abnormal_inner_ear0.00988596
134MP0001756_abnormal_urination0.00920228
135MP0005167_abnormal_blood-brain_barrier0.00919212
136MP0002064_seizures0.00164288
137MP0006036_abnormal_mitochondrial_physio0.00016725
138MP0005220_abnormal_exocrine_pancreas-0.0024819

Predicted human phenotypes

RankGene SetZ-score
1Ocular albinism (HP:0001107)9.19535911
2Hypopigmentation of the fundus (HP:0007894)8.94784303
3Iris hypopigmentation (HP:0007730)8.05369349
4Generalized hypopigmentation (HP:0007513)6.56448547
5White forelock (HP:0002211)6.13260806
6Subacute progressive viral hepatitis (HP:0006572)6.09118058
7Congenital sensorineural hearing impairment (HP:0008527)5.79135941
8Patchy hypopigmentation of hair (HP:0011365)5.46876224
9Hypoplasia of the iris (HP:0007676)4.89613913
10Freckling (HP:0001480)4.69504860
11Cutaneous melanoma (HP:0012056)4.61072938
12Heterochromia iridis (HP:0001100)4.31904326
13Generalized hypopigmentation of hair (HP:0011358)4.05033823
14Bilateral sensorineural hearing impairment (HP:0008619)3.91980467
15Aplasia/Hypoplasia affecting the fundus (HP:0008057)3.82484195
16Decreased electroretinogram (ERG) amplitude (HP:0000654)3.81534412
17Premature graying of hair (HP:0002216)3.68170910
18Viral hepatitis (HP:0006562)3.39613336
19Micronodular cirrhosis (HP:0001413)3.33903140
20Peripheral hypomyelination (HP:0007182)3.15185090
21Albinism (HP:0001022)3.09841455
22Hepatocellular carcinoma (HP:0001402)2.77374531
23Melanoma (HP:0002861)2.53409072
24Congenital stationary night blindness (HP:0007642)2.53047214
25Abnormality of glycolipid metabolism (HP:0010969)2.40500451
26Abnormality of liposaccharide metabolism (HP:0010968)2.40500451
27Abnormality of glycosphingolipid metabolism (HP:0004343)2.40500451
28Attenuation of retinal blood vessels (HP:0007843)2.24973837
29Cerebral hypomyelination (HP:0006808)2.23630524
30Decreased central vision (HP:0007663)2.07913119
31Abnormality of vision evoked potentials (HP:0000649)2.03677023
32Alacrima (HP:0000522)2.00597186
33Aplasia/Hypoplasia of the macula (HP:0008059)12.4345624
34Aplasia/Hypoplasia of the fovea (HP:0008060)11.7586221
35Hypoplasia of the fovea (HP:0007750)11.7586221
36Aplasia/Hypoplasia affecting the retina (HP:0008061)11.6390470
37Blue irides (HP:0000635)11.0484804
38Abnormality of the fovea (HP:0000493)10.6139867
39Asymmetric septal hypertrophy (HP:0001670)1.98237832
40Spastic diplegia (HP:0001264)1.87009070
41Abnormal auditory evoked potentials (HP:0006958)1.86886634
42Morphological abnormality of the inner ear (HP:0011390)1.84706953
43Large for gestational age (HP:0001520)1.84319960
44Scapular winging (HP:0003691)1.83601742
45Rhabdomyosarcoma (HP:0002859)1.79729085
46Amblyopia (HP:0000646)1.79715811
47Exercise-induced muscle cramps (HP:0003710)1.74503374
48Renal cell carcinoma (HP:0005584)1.73426414
49Abnormal autonomic nervous system physiology (HP:0012332)1.71626452
50Cholecystitis (HP:0001082)1.69264082
51Abnormal gallbladder physiology (HP:0012438)1.69264082
52J-shaped sella turcica (HP:0002680)1.63978384
53Decreased lacrimation (HP:0000633)1.62443033
54Underdeveloped nasal alae (HP:0000430)1.62351546
55Hypermelanotic macule (HP:0001034)1.61314820
56Increased neuronal autofluorescent lipopigment (HP:0002074)1.58274947
57Melanocytic nevus (HP:0000995)1.57548652
58Synophrys (HP:0000664)1.54375615
59Horizontal nystagmus (HP:0000666)1.53431896
60Ulnar claw (HP:0001178)1.53368420
61Photophobia (HP:0000613)1.53159536
62Urinary glycosaminoglycan excretion (HP:0003541)1.51466166
63Mucopolysacchariduria (HP:0008155)1.51466166
64Poor head control (HP:0002421)1.50518429
65Lip pit (HP:0100267)1.49648249
66Abnormality of the anterior horn cell (HP:0006802)1.49259737
67Degeneration of anterior horn cells (HP:0002398)1.49259737
68Keratoconus (HP:0000563)1.48791614
69Increased corneal curvature (HP:0100692)1.48791614
70Increased cerebral lipofuscin (HP:0011813)1.46600233
71Astigmatism (HP:0000483)1.43702353
72Morphological abnormality of the middle ear (HP:0008609)1.42189123
73Hepatitis (HP:0012115)1.40298515
74Tongue fasciculations (HP:0001308)1.37933175
75Aplasia cutis congenita (HP:0001057)1.35975527
76Vertebral compression fractures (HP:0002953)1.35834689
77Neoplasm of the oral cavity (HP:0100649)1.34458520
78Conjunctival hamartoma (HP:0100780)1.33326333
79Abnormality of mucopolysaccharide metabolism (HP:0011020)1.31229746
80Abnormality of polysaccharide metabolism (HP:0011012)1.31229746
81Abnormality of glycosaminoglycan metabolism (HP:0004371)1.31229746
82Adrenal hypoplasia (HP:0000835)1.30741290
83Abnormality of the anterior chamber (HP:0000593)1.25084425
84Hypokinesia (HP:0002375)1.23825949
85Hamartoma of the eye (HP:0010568)1.22552069
86Upper limb muscle weakness (HP:0003484)1.22192392
87Supernumerary ribs (HP:0005815)1.21749666
88Neoplasm of striated muscle (HP:0009728)1.21258573
89Neoplasm of the liver (HP:0002896)1.19821204
90Hypermetropia (HP:0000540)1.17702991
91Clumsiness (HP:0002312)1.17667266
92Loss of speech (HP:0002371)1.16983335
93Abnormality of the nasal septum (HP:0000419)1.16976977
94Aortic aneurysm (HP:0004942)1.16775095
95Hand muscle atrophy (HP:0009130)1.16204900
96Tented upper lip vermilion (HP:0010804)1.16113596
97Dysostosis multiplex (HP:0000943)1.15350487
98Impaired proprioception (HP:0010831)1.13889319
99Frequent falls (HP:0002359)1.13758988
100Facial cleft (HP:0002006)1.12882761
101Premature rupture of membranes (HP:0001788)1.12709966
102Akinesia (HP:0002304)1.12506689
103Ulnar deviation of finger (HP:0009465)1.11300169
104Muscle fibrillation (HP:0010546)1.10769788
105CNS hypomyelination (HP:0003429)1.10599032
106Cerebral aneurysm (HP:0004944)1.10245961
107Visual hallucinations (HP:0002367)1.07827628
108Narrow nasal bridge (HP:0000446)1.07820544
109Supernumerary nipples (HP:0002558)1.07255288
110Leukodystrophy (HP:0002415)1.07242665
111Global brain atrophy (HP:0002283)1.05671215
112Spastic paraplegia (HP:0001258)1.05514825
113Abnormality of the shoulder girdle musculature (HP:0001435)1.03945245
114Supernumerary bones of the axial skeleton (HP:0009144)1.03308845
115Aganglionic megacolon (HP:0002251)1.02996285
116Spinal muscular atrophy (HP:0007269)1.02150511
117Constricted visual fields (HP:0001133)1.01681836
118Action tremor (HP:0002345)1.01380845
119Long toe (HP:0010511)1.01284529
120Cerebral inclusion bodies (HP:0100314)1.00959376
121Postural tremor (HP:0002174)1.00865221
122Synostosis of carpal bones (HP:0005048)1.00726294
123Vascular tortuosity (HP:0004948)1.00619704
124Megalencephaly (HP:0001355)1.00120662
125Absent epiphyses (HP:0010577)0.99550371
126Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)0.99550371
127Diminished movement (HP:0002374)0.99350047
128Myelomeningocele (HP:0002475)0.98452547
129Decreased motor nerve conduction velocity (HP:0003431)0.97117580
130Insidious onset (HP:0003587)0.95527433
131Termporal pattern (HP:0011008)0.95527433
132Distal upper limb amyotrophy (HP:0007149)0.95497967
133Upper limb amyotrophy (HP:0009129)0.95497967
134Carpal synostosis (HP:0009702)0.94933145
135Proximal amyotrophy (HP:0007126)0.93822672
136Nasal speech (HP:0001611)0.92639029
137Tracheomalacia (HP:0002779)0.92203444
138Intestinal polyposis (HP:0200008)0.92011303
139Hypoplasia of the capital femoral epiphysis (HP:0003090)0.91680299
140Mesangial abnormality (HP:0001966)0.91549851
141Paraplegia (HP:0010550)0.91483288
142Overlapping toe (HP:0001845)0.91013318
143Abnormality of the salivary glands (HP:0010286)0.90828335
144Bladder diverticulum (HP:0000015)0.90293387
145Asymmetry of the thorax (HP:0001555)0.90275621
146Coarse hair (HP:0002208)0.88670918
147Paraparesis (HP:0002385)0.87455405
148Hypopigmented skin patches (HP:0001053)0.87054496
149Ulnar deviation of the hand or of fingers of the hand (HP:0001193)0.85174615
150Spastic paraparesis (HP:0002313)0.84369923
151Atelectasis (HP:0100750)0.81945967
152Bladder carcinoma (HP:0002862)0.81179355
153Bladder neoplasm (HP:0009725)0.81179355
154Myoglobinuria (HP:0002913)0.80705077
155Distal sensory impairment (HP:0002936)0.78807371
156Aneurysm (HP:0002617)0.78800229
157Uterine leiomyosarcoma (HP:0002891)0.78627292
158Leiomyosarcoma (HP:0100243)0.78627292
159Exostoses (HP:0100777)0.78539498
160Angiofibromas (HP:0010615)0.78381998

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MET5.71402680
2PDK24.25591933
3MARK33.98003805
4BMX3.89546225
5PKN23.81898737
6WEE13.13640070
7TRIB32.56855713
8MAP3K32.45626198
9CDK32.03826962
10MST1R13.0794816
11PRKD31.99639057
12EPHA31.95380385
13TRIM281.71844589
14PRKCH1.58695470
15BMPR1B1.54919038
16SCYL21.53040440
17EIF2AK11.36658919
18MAP3K21.32561939
19DDR21.22384808
20ACVR1B1.20256366
21ERBB31.19568393
22PTK2B1.18428289
23LATS11.16967486
24TTN1.14004411
25KIT1.11874196
26FLT31.07395768
27SIK31.06173191
28NEK11.04922302
29ICK0.99757094
30MATK0.99314174
31PTK60.87941676
32LRRK20.82896025
33GSK3A0.82890175
34BMPR20.82845126
35CCNB10.81813140
36NEK60.77679387
37ABL20.77562460
38MAP4K10.67694697
39PAK40.66437446
40PLK10.64791678
41RPS6KB20.64186730
42CSNK1G10.61544211
43GRK60.60513209
44ADRBK10.57678591
45FER0.56082577
46CAMKK10.54425249
47GRK50.53407405
48PRKD20.52833695
49KSR20.51159227
50CSNK1G30.50690962
51RET0.49415279
52KSR10.49259577
53PDGFRA0.48510915
54CSNK1A1L0.48247206
55ILK0.46788067
56CHUK0.46563934
57INSRR0.46053142
58RIPK10.45947858
59MAPK70.44483579
60OBSCN0.44004266
61ADRBK20.43102507
62CSNK1A10.40499293
63BRSK10.40173066
64MAPK130.39523342
65PRKAA20.38288462
66AKT20.37533053
67MAP2K10.37280949
68CSNK1G20.36682425
69PRKG20.36063725
70ZAP700.35675834
71MAPK110.34922317
72CDK60.34388759
73WNK40.33767381
74CDK180.33733432
75GRK10.33482578
76TGFBR10.33229770
77CDK70.33212364
78CLK10.33109409
79ATR0.31838427
80PHKG20.31323786
81PHKG10.31323786
82MAP3K90.30395576
83ZAK0.30251695
84LMTK20.29728851
85CDC70.29360752
86TYK20.29339197
87STK40.29056995
88WNK30.28919481
89DMPK0.28815912
90MAP3K80.28809745
91FGFR40.27751268
92INSR0.27172246
93MAP3K130.26813799
94MAPKAPK50.26483822
95CDK11A0.26265021
96CDK150.25698989
97EEF2K0.24856149
98CAMKK20.24766529
99PRKCE0.23876168
100FRK0.23477802
101DYRK1A0.23341582
102PAK60.23155671
103MAP3K110.22848966
104TAOK30.22780376
105ATM0.22614627
106TBK10.22115988
107PRKCZ0.21955870
108MAPK120.20959402
109EGFR0.20817313
110BCKDK0.20391162
111MAPKAPK30.20389123
112ALK0.19437809
113CHEK20.19409583
114LATS20.18974737
115RAF10.18748338
116FGFR10.17343772
117CDK40.17188751
118FGFR30.16763112
119STK30.16566258
120BRSK20.16320909
121NEK20.16058223
122TLK10.15535978
123PAK30.15263762
124PAK20.15024943
125NTRK10.14600942
126RPS6KA10.14305092
127FGFR20.14023462
128CSNK1D0.12670339
129PDGFRB0.10895540
130IGF1R0.10801528
131TGFBR20.10089239
132FGR0.09734026
133PLK30.09722991
134ABL10.09375239
135TYRO30.08933707
136ARAF0.08796166
137SRC0.08589807
138SGK30.08212677
139PRKACB0.07975824
140CAMK1D0.07775574
141MAPK30.07215727
142PLK20.06740033
143DYRK1B0.06027091
144EIF2AK30.05091479
145NEK90.05066659
146PTK20.04784011
147MOS0.04464591
148SGK20.03977254
149MTOR0.03534661
150PRKD10.03422999
151ERBB20.03412934
152AURKA0.03210960
153TRPM70.03020624
154AKT10.02935660
155MAP2K60.01996161
156PDK10.01756692

Predicted pathways (KEGG)

RankGene SetZ-score
1Melanogenesis_Homo sapiens_hsa049163.97700654
2Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.79216374
3Glycosaminoglycan degradation_Homo sapiens_hsa005313.37329298
4Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.80468112
5Central carbon metabolism in cancer_Homo sapiens_hsa052302.74923444
6Other glycan degradation_Homo sapiens_hsa005112.72610693
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.39172598
8Galactose metabolism_Homo sapiens_hsa000522.30491873
9Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.25345275
10Proteasome_Homo sapiens_hsa030502.19313099
11Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.14950388
12Oxidative phosphorylation_Homo sapiens_hsa001902.11027257
13Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.06401790
14Sphingolipid metabolism_Homo sapiens_hsa006002.03839683
15Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.01514825
16Tyrosine metabolism_Homo sapiens_hsa0035010.4097370
17Melanoma_Homo sapiens_hsa052181.94838431
18Non-homologous end-joining_Homo sapiens_hsa034501.92204330
19Renal cell carcinoma_Homo sapiens_hsa052111.90162860
20Protein export_Homo sapiens_hsa030601.86791763
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.74057186
22Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.73912942
23Nitrogen metabolism_Homo sapiens_hsa009101.70517661
24Retinol metabolism_Homo sapiens_hsa008301.62605416
25Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.62513177
26Phototransduction_Homo sapiens_hsa047441.60131741
27Biosynthesis of amino acids_Homo sapiens_hsa012301.56369437
28Adherens junction_Homo sapiens_hsa045201.55040984
29Fructose and mannose metabolism_Homo sapiens_hsa000511.46472617
30Primary bile acid biosynthesis_Homo sapiens_hsa001201.45853657
31Fatty acid elongation_Homo sapiens_hsa000621.44767099
32One carbon pool by folate_Homo sapiens_hsa006701.40513989
33Starch and sucrose metabolism_Homo sapiens_hsa005001.32898544
34ABC transporters_Homo sapiens_hsa020101.32864354
35Parkinsons disease_Homo sapiens_hsa050121.30734653
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.29896070
37Homologous recombination_Homo sapiens_hsa034401.29893896
38Systemic lupus erythematosus_Homo sapiens_hsa053221.26693702
39Alzheimers disease_Homo sapiens_hsa050101.25797769
40Carbon metabolism_Homo sapiens_hsa012001.22963946
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.19523254
42Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.17915842
43Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.12337135
44HIF-1 signaling pathway_Homo sapiens_hsa040661.11283362
45Pentose phosphate pathway_Homo sapiens_hsa000301.09048988
46Malaria_Homo sapiens_hsa051441.02636764
47Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.01853818
48Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.01250753
49Fanconi anemia pathway_Homo sapiens_hsa034601.00172079
50SNARE interactions in vesicular transport_Homo sapiens_hsa041300.99405408
51alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.98935047
52Phenylalanine metabolism_Homo sapiens_hsa003600.93138629
53MicroRNAs in cancer_Homo sapiens_hsa052060.92327885
54Proteoglycans in cancer_Homo sapiens_hsa052050.89965548
55Focal adhesion_Homo sapiens_hsa045100.89253012
56Linoleic acid metabolism_Homo sapiens_hsa005910.85734273
57Glioma_Homo sapiens_hsa052140.82452482
58Small cell lung cancer_Homo sapiens_hsa052220.79808111
59Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.77024609
60Lysosome_Homo sapiens_hsa041420.76567177
61N-Glycan biosynthesis_Homo sapiens_hsa005100.76495753
62Tight junction_Homo sapiens_hsa045300.76412024
63mTOR signaling pathway_Homo sapiens_hsa041500.74780473
64Vibrio cholerae infection_Homo sapiens_hsa051100.74319938
65Synaptic vesicle cycle_Homo sapiens_hsa047210.73782251
66RNA degradation_Homo sapiens_hsa030180.73112634
67RNA polymerase_Homo sapiens_hsa030200.69968149
68Basal transcription factors_Homo sapiens_hsa030220.69580413
69Alcoholism_Homo sapiens_hsa050340.67402271
70Huntingtons disease_Homo sapiens_hsa050160.67152561
71Fat digestion and absorption_Homo sapiens_hsa049750.67087703
72Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66295099
73Glutathione metabolism_Homo sapiens_hsa004800.65471481
74Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63715491
75Chronic myeloid leukemia_Homo sapiens_hsa052200.62591399
76Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.61847267
77Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.61748732
78Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.60974911
79Viral carcinogenesis_Homo sapiens_hsa052030.59820686
80Pentose and glucuronate interconversions_Homo sapiens_hsa000400.59367435
81Bile secretion_Homo sapiens_hsa049760.59050722
82Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.57439152
83Collecting duct acid secretion_Homo sapiens_hsa049660.56954745
84Axon guidance_Homo sapiens_hsa043600.56625774
85Vitamin digestion and absorption_Homo sapiens_hsa049770.50061835
86Neurotrophin signaling pathway_Homo sapiens_hsa047220.49321125
87Estrogen signaling pathway_Homo sapiens_hsa049150.49081618
88Regulation of autophagy_Homo sapiens_hsa041400.49053537
89Peroxisome_Homo sapiens_hsa041460.48740814
90Insulin signaling pathway_Homo sapiens_hsa049100.46720855
91Glucagon signaling pathway_Homo sapiens_hsa049220.46629002
92Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.45245331
93Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.44967935
94Lysine degradation_Homo sapiens_hsa003100.44207275
95Rheumatoid arthritis_Homo sapiens_hsa053230.43053280
96VEGF signaling pathway_Homo sapiens_hsa043700.41940550
97Endometrial cancer_Homo sapiens_hsa052130.40278812
98Sulfur relay system_Homo sapiens_hsa041220.40037209
99Circadian rhythm_Homo sapiens_hsa047100.39090895
100Prostate cancer_Homo sapiens_hsa052150.38690218
101Rap1 signaling pathway_Homo sapiens_hsa040150.38460865
102Butanoate metabolism_Homo sapiens_hsa006500.37694727
103Inositol phosphate metabolism_Homo sapiens_hsa005620.36776760
104Phagosome_Homo sapiens_hsa041450.36200378
105Folate biosynthesis_Homo sapiens_hsa007900.35892982
106Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.35737285
107Ras signaling pathway_Homo sapiens_hsa040140.33323323
108p53 signaling pathway_Homo sapiens_hsa041150.32403070
109Dorso-ventral axis formation_Homo sapiens_hsa043200.31781466
110Oocyte meiosis_Homo sapiens_hsa041140.31198553
111Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.29841854
112Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.28307719
113Vascular smooth muscle contraction_Homo sapiens_hsa042700.28110503
114Calcium signaling pathway_Homo sapiens_hsa040200.27501867
115Cysteine and methionine metabolism_Homo sapiens_hsa002700.27457847
116Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.27037840
117Chemical carcinogenesis_Homo sapiens_hsa052040.26619320
118Pathways in cancer_Homo sapiens_hsa052000.25574039
119Thyroid cancer_Homo sapiens_hsa052160.23792180
120Sulfur metabolism_Homo sapiens_hsa009200.23162724
121Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.23123499
122Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.22930407
123Dilated cardiomyopathy_Homo sapiens_hsa054140.22754332
124Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.22665743
125Prolactin signaling pathway_Homo sapiens_hsa049170.22521971
126ErbB signaling pathway_Homo sapiens_hsa040120.22326917
127Colorectal cancer_Homo sapiens_hsa052100.21788831
128Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.21705376
129Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.21403550
130Histidine metabolism_Homo sapiens_hsa003400.21101946
131beta-Alanine metabolism_Homo sapiens_hsa004100.20057443
132Metabolic pathways_Homo sapiens_hsa011000.20016725
133Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.19685022
134ECM-receptor interaction_Homo sapiens_hsa045120.19549807
135Thyroid hormone signaling pathway_Homo sapiens_hsa049190.19534445
136PI3K-Akt signaling pathway_Homo sapiens_hsa041510.18493575
137Mismatch repair_Homo sapiens_hsa034300.17212889
138Olfactory transduction_Homo sapiens_hsa047400.16718358
139Insulin resistance_Homo sapiens_hsa049310.16690771
140Osteoclast differentiation_Homo sapiens_hsa043800.16398288
141Propanoate metabolism_Homo sapiens_hsa006400.15798894
142Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.15751613
143AMPK signaling pathway_Homo sapiens_hsa041520.15722281
144Endocytosis_Homo sapiens_hsa041440.15627534
145Pyrimidine metabolism_Homo sapiens_hsa002400.15284681
146Non-small cell lung cancer_Homo sapiens_hsa052230.14834691
147Drug metabolism - other enzymes_Homo sapiens_hsa009830.14321080
148Fatty acid metabolism_Homo sapiens_hsa012120.14157486
149Arginine biosynthesis_Homo sapiens_hsa002200.13256674
150Transcriptional misregulation in cancer_Homo sapiens_hsa052020.13192159
151Phosphatidylinositol signaling system_Homo sapiens_hsa040700.13159294
152cGMP-PKG signaling pathway_Homo sapiens_hsa040220.12819132
153Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.12682106
154Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.12680457
155Cyanoamino acid metabolism_Homo sapiens_hsa004600.11943080
156Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.11722219
157Ether lipid metabolism_Homo sapiens_hsa005650.11376088
158Cell cycle_Homo sapiens_hsa041100.11335780
159Glycerophospholipid metabolism_Homo sapiens_hsa005640.10820284

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