MLLT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1layer formation in cerebral cortex (GO:0021819)4.69111093
2cytoskeletal anchoring at plasma membrane (GO:0007016)3.87031076
3peptidyl-lysine dimethylation (GO:0018027)3.87020900
4negative regulation of erythrocyte differentiation (GO:0045647)3.77880613
5cell-cell junction maintenance (GO:0045217)3.73387037
6negative regulation of cell size (GO:0045792)3.71629122
7regulation of early endosome to late endosome transport (GO:2000641)3.71051408
8pre-miRNA processing (GO:0031054)3.50847414
9planar cell polarity pathway involved in neural tube closure (GO:0090179)3.50676737
10glial cell proliferation (GO:0014009)3.47288847
11regulation of NFAT protein import into nucleus (GO:0051532)3.44484365
12protein retention in ER lumen (GO:0006621)3.43179901
13establishment of nucleus localization (GO:0040023)3.40911239
14locomotory exploration behavior (GO:0035641)3.40559100
15cerebellar granule cell differentiation (GO:0021707)3.38608671
16regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.36779174
17glucocorticoid receptor signaling pathway (GO:0042921)3.31542856
18apoptotic process involved in morphogenesis (GO:0060561)3.27413704
19dendritic spine morphogenesis (GO:0060997)3.24155913
20maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.22758550
21adherens junction assembly (GO:0034333)3.16526033
22negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.12421245
23plasma membrane repair (GO:0001778)3.10065608
24positive regulation of histone deacetylation (GO:0031065)3.08222522
25protein-DNA complex disassembly (GO:0032986)3.04862520
26nucleosome disassembly (GO:0006337)3.04862520
27maternal placenta development (GO:0001893)3.04647014
28stress fiber assembly (GO:0043149)3.04333883
29negative regulation of catenin import into nucleus (GO:0035414)3.01060411
30glutamate secretion (GO:0014047)3.00962443
31camera-type eye morphogenesis (GO:0048593)2.99845945
32peptidyl-arginine omega-N-methylation (GO:0035247)2.99096274
33protein targeting to plasma membrane (GO:0072661)2.98695739
34positive regulation of synapse maturation (GO:0090129)2.95810104
35synaptic vesicle maturation (GO:0016188)2.95766364
36G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.95029283
37negative regulation of fatty acid transport (GO:2000192)2.94605689
38hippo signaling (GO:0035329)2.94029944
39regulation of ARF GTPase activity (GO:0032312)2.93254349
40mRNA stabilization (GO:0048255)2.92864794
41RNA stabilization (GO:0043489)2.92864794
42activation of Rac GTPase activity (GO:0032863)2.91096918
43heterochromatin organization (GO:0070828)2.90700179
44vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.89526849
45cell migration in hindbrain (GO:0021535)2.87152350
46epithelial cell differentiation involved in prostate gland development (GO:0060742)2.87111655
47peptidyl-arginine N-methylation (GO:0035246)2.86440662
48peptidyl-arginine methylation (GO:0018216)2.86440662
49cellular potassium ion homeostasis (GO:0030007)2.84382032
50corticosteroid receptor signaling pathway (GO:0031958)2.81400064
51regulation of mammary gland epithelial cell proliferation (GO:0033599)2.81224461
52negative regulation of RNA splicing (GO:0033119)2.81145447
53activation of MAPKKK activity (GO:0000185)2.80722992
54insulin-like growth factor receptor signaling pathway (GO:0048009)2.79376482
55positive regulation of RNA splicing (GO:0033120)2.77310054
56synaptic vesicle exocytosis (GO:0016079)2.74212504
57polarized epithelial cell differentiation (GO:0030859)2.74002042
58regulation of synapse structural plasticity (GO:0051823)2.73856569
59embryonic foregut morphogenesis (GO:0048617)2.73682840
60DNA unwinding involved in DNA replication (GO:0006268)2.72336227
61regulation of hippo signaling (GO:0035330)2.72007973
62regulation of glucose import in response to insulin stimulus (GO:2001273)2.71293713
63intracellular estrogen receptor signaling pathway (GO:0030520)2.70803173
64NLS-bearing protein import into nucleus (GO:0006607)2.70612975
65retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.70439335
66mannose metabolic process (GO:0006013)2.69986147
67positive regulation of blood vessel endothelial cell migration (GO:0043536)2.69719860
68COPI coating of Golgi vesicle (GO:0048205)2.68702424
69Golgi transport vesicle coating (GO:0048200)2.68702424
70positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.67656702
71atrioventricular valve morphogenesis (GO:0003181)2.67563066
72cell-substrate adherens junction assembly (GO:0007045)2.66996828
73focal adhesion assembly (GO:0048041)2.66996828
74semaphorin-plexin signaling pathway (GO:0071526)2.66909069
75response to parathyroid hormone (GO:0071107)2.66609517
76negative regulation of microtubule polymerization (GO:0031115)2.66293244
77regulation of translational fidelity (GO:0006450)2.66154877
78basement membrane organization (GO:0071711)2.65993737
79sodium ion export (GO:0071436)2.65393543
80regulation of translational termination (GO:0006449)2.63615655
81convergent extension (GO:0060026)2.63149482
82positive regulation of dendrite morphogenesis (GO:0050775)2.60985143
83dopamine receptor signaling pathway (GO:0007212)2.60038913
84positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.59190842
85modulation by virus of host morphology or physiology (GO:0019048)2.58603412
86positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.58190629
87cell junction maintenance (GO:0034331)2.57878814
88clathrin coat assembly (GO:0048268)2.55543410
89neuromuscular process controlling balance (GO:0050885)2.55537322
90gastrulation with mouth forming second (GO:0001702)2.55473976
91cerebellar Purkinje cell layer development (GO:0021680)2.54959979
92endothelial cell chemotaxis (GO:0035767)2.50954104
93positive regulation of protein dephosphorylation (GO:0035307)2.50176038
94neural tube development (GO:0021915)2.49312448
95apoptotic process involved in development (GO:1902742)2.48902262
96positive regulation of fibroblast migration (GO:0010763)2.48590358
97establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.48046759
98negative regulation of mRNA processing (GO:0050686)2.47748733
99positive regulation of glycogen biosynthetic process (GO:0045725)2.47530630
100collecting duct development (GO:0072044)2.45706842
101skeletal muscle organ development (GO:0060538)2.42946207
102cell communication by electrical coupling (GO:0010644)2.42679040
103modulation by symbiont of host cellular process (GO:0044068)2.42074449
104cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.41855281
105cortical actin cytoskeleton organization (GO:0030866)2.41485689
106cellular response to catecholamine stimulus (GO:0071870)2.41113574
107cellular response to monoamine stimulus (GO:0071868)2.41113574
108barbed-end actin filament capping (GO:0051016)2.41047645
109cochlea morphogenesis (GO:0090103)2.40719703
110negative regulation of mRNA metabolic process (GO:1903312)2.40609704
111activation of protein kinase A activity (GO:0034199)2.40056253
112cell-substrate junction assembly (GO:0007044)2.39807175
113positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.39627447
114dendrite morphogenesis (GO:0048813)2.39190172
115positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.38997036
116regulation of short-term neuronal synaptic plasticity (GO:0048172)2.38268146
117axon extension (GO:0048675)2.37989540
118eye morphogenesis (GO:0048592)2.37409958
119respiratory system process (GO:0003016)2.36817041
120vocalization behavior (GO:0071625)2.36309761
121modulation by virus of host process (GO:0019054)2.34571452
122regulation of ARF protein signal transduction (GO:0032012)2.34457688
123exploration behavior (GO:0035640)2.34099945
124peptidyl-tyrosine autophosphorylation (GO:0038083)2.34069914
125skin morphogenesis (GO:0043589)2.33457597
126cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.33091619
127regulation of synaptic vesicle exocytosis (GO:2000300)2.32813456
128axon extension involved in axon guidance (GO:0048846)2.32609708
129neuron projection extension involved in neuron projection guidance (GO:1902284)2.32609708
130regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.32248592
131cell migration involved in heart development (GO:0060973)2.32017084
132vascular endothelial growth factor signaling pathway (GO:0038084)2.31834066
133response to laminar fluid shear stress (GO:0034616)2.31796741
134signal complex assembly (GO:0007172)2.31666087
135Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.31506900
136negative regulation of nucleotide catabolic process (GO:0030812)2.30835496
137neuronal ion channel clustering (GO:0045161)2.30807809
138protein localization to endosome (GO:0036010)2.29848573
139cellular response to epidermal growth factor stimulus (GO:0071364)2.29217725
140regulation of chromatin binding (GO:0035561)2.28863465
141regulation of establishment of planar polarity (GO:0090175)2.28228811
142peptidyl-threonine modification (GO:0018210)2.27845417
143cardiac myofibril assembly (GO:0055003)2.27578838
144negative regulation of organelle assembly (GO:1902116)2.27476251
145protein heterotrimerization (GO:0070208)2.27162185
146neuron projection extension (GO:1990138)2.26929439
1473-UTR-mediated mRNA stabilization (GO:0070935)2.26597891
148peptidyl-threonine phosphorylation (GO:0018107)2.26201200
149positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.25474777
150regulation of fatty acid beta-oxidation (GO:0031998)2.25373803
151cytoplasmic mRNA processing body assembly (GO:0033962)2.25131850
152positive regulation of axon extension (GO:0045773)2.24851270
153regulation of mRNA stability (GO:0043488)2.24718737
154negative regulation of histone methylation (GO:0031061)2.24453788
155receptor catabolic process (GO:0032801)2.24305420
156synaptic vesicle docking involved in exocytosis (GO:0016081)2.23517653
157activation of JUN kinase activity (GO:0007257)2.21411675
158dosage compensation (GO:0007549)2.20145508
159body morphogenesis (GO:0010171)2.19929616
160negative regulation of heart growth (GO:0061117)2.19283824
161negative regulation of cardiac muscle tissue growth (GO:0055022)2.19283824

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_22102868_ChIP-Seq_BL_Human3.55556206
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.45783588
3STAT6_21828071_ChIP-Seq_BEAS2B_Human3.01579589
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.99515664
5KDM2B_26808549_Chip-Seq_DND41_Human2.88686259
6KDM2B_26808549_Chip-Seq_SUP-B15_Human2.88486294
7EGR1_19374776_ChIP-ChIP_THP-1_Human2.79472410
8ZFP281_18757296_ChIP-ChIP_E14_Mouse2.75056460
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.72577229
10TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.71389068
11KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.52080606
12TCF7_22412390_ChIP-Seq_EML_Mouse2.52006844
13ZNF263_19887448_ChIP-Seq_K562_Human2.40590865
14KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.39789477
15* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.39295228
16ZFP281_27345836_Chip-Seq_ESCs_Mouse2.35941038
17* LXR_22292898_ChIP-Seq_THP-1_Human2.30326180
18KDM2B_26808549_Chip-Seq_K562_Human2.28137413
19VDR_21846776_ChIP-Seq_THP-1_Human2.26510667
20KDM2B_26808549_Chip-Seq_JURKAT_Human2.26275296
21E2F7_22180533_ChIP-Seq_HELA_Human2.21429324
22* ELK3_25401928_ChIP-Seq_HUVEC_Human2.18211465
23EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.09395386
24* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.08274463
25DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.00844616
26TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.92710504
27TP63_17297297_ChIP-ChIP_HaCaT_Human1.90248064
28P300_27058665_Chip-Seq_ZR-75-30cells_Human1.89932667
29* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.89345136
30MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.83311746
31TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.72683974
32EZH2_22144423_ChIP-Seq_EOC_Human1.69958542
33RARB_27405468_Chip-Seq_BRAIN_Mouse1.68527538
34RACK7_27058665_Chip-Seq_MCF-7_Human1.63221126
35RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.62111705
36DNAJC2_21179169_ChIP-ChIP_NT2_Human1.61229509
37NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.59463239
38TET1_21451524_ChIP-Seq_MESCs_Mouse1.58393321
39CREB1_26743006_Chip-Seq_LNCaP_Human1.56665662
40KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.56602302
41TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.54066356
42UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.51101663
43SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.49486277
44SRY_22984422_ChIP-ChIP_TESTIS_Rat1.48080014
45UTX_26944678_Chip-Seq_JUKART_Human1.45802347
46DROSHA_22980978_ChIP-Seq_HELA_Human1.43748876
47TP53_22127205_ChIP-Seq_IMR90_Human1.40883909
48RARG_19884340_ChIP-ChIP_MEFs_Mouse1.39017583
49PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.36535282
50KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.35325150
51MAF_26560356_Chip-Seq_TH1_Human1.35127320
52CLOCK_20551151_ChIP-Seq_293T_Human1.33901865
53SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.32567924
54GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29969965
55THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.29228625
56EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.27610087
57CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.26966547
58CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.26813031
59* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.25678470
60STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.25007752
61* TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.24922205
62CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.24034703
63P68_20966046_ChIP-Seq_HELA_Human1.23406538
64CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.21286371
65RUNX1_27514584_Chip-Seq_MCF-7_Human1.21043864
66ATF3_27146783_Chip-Seq_COLON_Human1.20763420
67KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.20397934
68VDR_24763502_ChIP-Seq_THP-1_Human1.19255181
69ERG_21242973_ChIP-ChIP_JURKAT_Human1.18830243
70NCOR1_26117541_ChIP-Seq_K562_Human1.16828912
71MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.16053779
72TET1_21490601_ChIP-Seq_MESCs_Mouse1.15695354
73RING1B_27294783_Chip-Seq_ESCs_Mouse1.15527732
74SA1_27219007_Chip-Seq_ERYTHROID_Human1.15467351
75* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.14913096
76RING1B_27294783_Chip-Seq_NPCs_Mouse1.14799468
77PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.14038231
78SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.13365786
79NFIB_24661679_ChIP-Seq_LUNG_Mouse1.12619643
80EZH2_18974828_ChIP-Seq_MESCs_Mouse1.12615898
81RNF2_18974828_ChIP-Seq_MESCs_Mouse1.12615898
82SMC4_20622854_ChIP-Seq_HELA_Human1.12599763
83ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.10420254
84TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.09718938
85EZH2_27304074_Chip-Seq_ESCs_Mouse1.09597168
86* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09452922
87NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.09357716
88ISL1_27105846_Chip-Seq_CPCs_Mouse1.08990191
89NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.07962562
90STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.07632399
91CTCF_27219007_Chip-Seq_ERYTHROID_Human1.07421970
92RNF2_27304074_Chip-Seq_ESCs_Mouse1.07088635
93ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.06815849
94WT1_25993318_ChIP-Seq_PODOCYTE_Human1.03722749
95STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.03238118
96DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.03004513
97CTCF_27219007_Chip-Seq_Bcells_Human1.02866465
98IKZF1_21737484_ChIP-ChIP_HCT116_Human1.02019779
99SUZ12_27294783_Chip-Seq_ESCs_Mouse1.01737214
100PKCTHETA_26484144_Chip-Seq_BREAST_Human1.01303310
101FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.01002292
102ELF1_20517297_ChIP-Seq_JURKAT_Human1.00332858
103TP53_20018659_ChIP-ChIP_R1E_Mouse1.00279589
104MTF2_20144788_ChIP-Seq_MESCs_Mouse1.00224832
105* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.00207606
106SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.00148829
107VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.00138752
108E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.98857371
109EZH2_27294783_Chip-Seq_ESCs_Mouse0.97155320
110TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.95937724
111* SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.95539961
112ESR2_21235772_ChIP-Seq_MCF-7_Human0.95334493
113FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.95220479
114OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.95066586
115TBX20_22328084_ChIP-Seq_HEART_Mouse0.94710712
116TBX20_22080862_ChIP-Seq_HEART_Mouse0.94710712
117ESR1_15608294_ChIP-ChIP_MCF-7_Human0.94254039
118JARID2_20075857_ChIP-Seq_MESCs_Mouse0.94227512
119MAF_26560356_Chip-Seq_TH2_Human0.94107781
120TRIM28_21343339_ChIP-Seq_HEK293_Human0.92788122
121TP53_23651856_ChIP-Seq_MEFs_Mouse0.90486918
122JARID2_20064375_ChIP-Seq_MESCs_Mouse0.89901684
123CIITA_25753668_ChIP-Seq_RAJI_Human0.89845778
124TP63_22573176_ChIP-Seq_HFKS_Human0.89560749

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.38607173
2MP0004859_abnormal_synaptic_plasticity3.37473573
3MP0000537_abnormal_urethra_morphology3.22204801
4MP0005076_abnormal_cell_differentiation2.86204741
5MP0009053_abnormal_anal_canal2.53474474
6MP0005409_darkened_coat_color2.42875683
7MP0005623_abnormal_meninges_morphology2.36420343
8MP0008961_abnormal_basal_metabolism2.23604212
9MP0000733_abnormal_muscle_development2.18146818
10MP0010352_gastrointestinal_tract_polyps2.17359366
11MP0010234_abnormal_vibrissa_follicle2.16563835
12MP0010030_abnormal_orbit_morphology2.12987061
13MP0004858_abnormal_nervous_system2.07850722
14MP0001849_ear_inflammation2.00761129
15MP0005257_abnormal_intraocular_pressure1.96851099
16MP0003115_abnormal_respiratory_system1.92020678
17MP0003300_gastrointestinal_ulcer1.91104738
18MP0000566_synostosis1.91087208
19MP0000534_abnormal_ureter_morphology1.89291812
20MP0003303_peritoneal_inflammation1.87972377
21MP0000678_abnormal_parathyroid_gland1.86343437
22MP0002234_abnormal_pharynx_morphology1.84636360
23MP0004233_abnormal_muscle_weight1.83801452
24MP0009379_abnormal_foot_pigmentation1.81712206
25MP0003385_abnormal_body_wall1.79065557
26MP0001348_abnormal_lacrimal_gland1.78036206
27MP0005503_abnormal_tendon_morphology1.74906853
28MP0005058_abnormal_lysosome_morphology1.67512203
29MP0009278_abnormal_bone_marrow1.67460590
30MP0005451_abnormal_body_composition1.57867550
31MP0005187_abnormal_penis_morphology1.56124669
32MP0000751_myopathy1.49900533
33MP0002089_abnormal_postnatal_growth/wei1.49541879
34MP0004197_abnormal_fetal_growth/weight/1.48782687
35MP0000428_abnormal_craniofacial_morphol1.48230413
36MP0003942_abnormal_urinary_system1.46092252
37MP0003123_paternal_imprinting1.46055216
38MP0003119_abnormal_digestive_system1.43137210
39MP0003879_abnormal_hair_cell1.39165758
40MP0003283_abnormal_digestive_organ1.38925765
41MP0005666_abnormal_adipose_tissue1.33252157
42MP0004185_abnormal_adipocyte_glucose1.31727301
43MP0003635_abnormal_synaptic_transmissio1.29436635
44MP0008260_abnormal_autophagy1.27522311
45MP0002084_abnormal_developmental_patter1.26537817
46MP0003861_abnormal_nervous_system1.25683935
47MP0008770_decreased_survivor_rate1.24125423
48MP0003634_abnormal_glial_cell1.24102893
49MP0008569_lethality_at_weaning1.23462688
50MP0003566_abnormal_cell_adhesion1.22927830
51MP0004808_abnormal_hematopoietic_stem1.22088103
52MP0005508_abnormal_skeleton_morphology1.20900124
53MP0000778_abnormal_nervous_system1.20154613
54MP0001730_embryonic_growth_arrest1.19400344
55MP0003091_abnormal_cell_migration1.18883014
56MP0004087_abnormal_muscle_fiber1.18521810
57MP0003279_aneurysm1.17228480
58MP0001346_abnormal_lacrimal_gland1.16857994
59MP0000569_abnormal_digit_pigmentation1.16040898
60MP0006054_spinal_hemorrhage1.15880066
61MP0003453_abnormal_keratinocyte_physiol1.15269974
62MP0010630_abnormal_cardiac_muscle1.13719837
63MP0002085_abnormal_embryonic_tissue1.13668117
64MP0002932_abnormal_joint_morphology1.13566393
65MP0000747_muscle_weakness1.12848646
66MP0002282_abnormal_trachea_morphology1.12820218
67MP0003122_maternal_imprinting1.12731120
68MP0004811_abnormal_neuron_physiology1.12419125
69MP0009672_abnormal_birth_weight1.11929835
70MP0003567_abnormal_fetal_cardiomyocyte1.10559734
71MP0002925_abnormal_cardiovascular_devel1.09294077
72MP0008438_abnormal_cutaneous_collagen1.08181587
73MP0003935_abnormal_craniofacial_develop1.07887342
74MP0003172_abnormal_lysosome_physiology1.07309634
75MP0004510_myositis1.06860965
76MP0000350_abnormal_cell_proliferation1.04953691
77MP0002063_abnormal_learning/memory/cond1.04772486
78MP0000767_abnormal_smooth_muscle1.02338633
79MP0002653_abnormal_ependyma_morphology1.01439661
80MP0009780_abnormal_chondrocyte_physiolo1.00754643
81MP0001958_emphysema0.99762600
82MP0002088_abnormal_embryonic_growth/wei0.99446981
83MP0003984_embryonic_growth_retardation0.98282998
84MP0001672_abnormal_embryogenesis/_devel0.98082614
85MP0005380_embryogenesis_phenotype0.98082614
86MP0002086_abnormal_extraembryonic_tissu0.97332196
87MP0003329_amyloid_beta_deposits0.96453488
88MP0009384_cardiac_valve_regurgitation0.94466273
89MP0000681_abnormal_thyroid_gland0.94259320
90MP0001697_abnormal_embryo_size0.93793563
91MP0005423_abnormal_somatic_nervous0.92133334
92MP0002081_perinatal_lethality0.91868290
93MP0005248_abnormal_Harderian_gland0.91365343
94MP0000579_abnormal_nail_morphology0.88923496
95* MP0002080_prenatal_lethality0.88859522
96MP0002152_abnormal_brain_morphology0.88657062
97MP0002116_abnormal_craniofacial_bone0.88607741
98MP0003111_abnormal_nucleus_morphology0.87310132
99MP0000759_abnormal_skeletal_muscle0.87140721
100MP0002396_abnormal_hematopoietic_system0.86993569
101MP0002092_abnormal_eye_morphology0.86101317
102MP0001299_abnormal_eye_distance/0.85868577
103MP0002249_abnormal_larynx_morphology0.85815857
104MP0003755_abnormal_palate_morphology0.84671854
105MP0000266_abnormal_heart_morphology0.84156993
106MP0000750_abnormal_muscle_regeneration0.83983693
107MP0005275_abnormal_skin_tensile0.83252195
108MP0000003_abnormal_adipose_tissue0.83071989
109MP0004130_abnormal_muscle_cell0.82941351
110MP0002877_abnormal_melanocyte_morpholog0.82711202
111MP0004272_abnormal_basement_membrane0.82417056
112MP0000049_abnormal_middle_ear0.82167647
113MP0009840_abnormal_foam_cell0.81662473
114MP0002060_abnormal_skin_morphology0.81444748
115MP0005023_abnormal_wound_healing0.80401405
116MP0004270_analgesia0.79875484
117MP0001784_abnormal_fluid_regulation0.79840070
118MP0000604_amyloidosis0.79616083
119MP0009703_decreased_birth_body0.79283782
120MP0006138_congestive_heart_failure0.78848501
121MP0009250_abnormal_appendicular_skeleto0.78706839
122MP0002896_abnormal_bone_mineralization0.78689357
123MP0005670_abnormal_white_adipose0.78217477
124MP0002697_abnormal_eye_size0.77688304
125MP0003121_genomic_imprinting0.76943197
126MP0003690_abnormal_glial_cell0.76846372
127MP0002114_abnormal_axial_skeleton0.76551110
128MP0001915_intracranial_hemorrhage0.76480726
129MP0000955_abnormal_spinal_cord0.75963250
130MP0003938_abnormal_ear_development0.75671635
131MP0000762_abnormal_tongue_morphology0.75613039
132MP0001502_abnormal_circadian_rhythm0.74402967
133MP0002108_abnormal_muscle_morphology0.74294413
134MP0005375_adipose_tissue_phenotype0.72881446
135MP0000858_altered_metastatic_potential0.72873551
136MP0002064_seizures0.70931470
137MP0005390_skeleton_phenotype0.69017914
138MP0004084_abnormal_cardiac_muscle0.68919782
139MP0000920_abnormal_myelination0.68469419
140MP0002998_abnormal_bone_remodeling0.68116493
141MP0005621_abnormal_cell_physiology0.67347524
142MP0004947_skin_inflammation0.67214403

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)4.17709209
2Short 4th metacarpal (HP:0010044)3.78745880
3Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.78745880
4Shallow orbits (HP:0000586)3.77552286
5Abnormality of the 4th metacarpal (HP:0010012)3.29393742
6Renal duplication (HP:0000075)3.28961757
7Protrusio acetabuli (HP:0003179)3.23446059
8Insomnia (HP:0100785)3.11458382
9Elfin facies (HP:0004428)3.00987764
10Overriding aorta (HP:0002623)2.96443814
11Renovascular hypertension (HP:0100817)2.89033181
12Pointed chin (HP:0000307)2.86467291
13Broad face (HP:0000283)2.71703745
14Cerebral aneurysm (HP:0004944)2.68003044
15Bladder diverticulum (HP:0000015)2.63153968
16Ankyloglossia (HP:0010296)2.60641206
17Abnormality of the lower motor neuron (HP:0002366)2.58260861
18Hallux valgus (HP:0001822)2.57752803
19Deviation of the hallux (HP:0010051)2.57450642
20Long palpebral fissure (HP:0000637)2.57168595
21Bowel diverticulosis (HP:0005222)2.55436807
22Increased density of long bones (HP:0006392)2.54802636
23Lymphangioma (HP:0100764)2.45125556
24Abnormality of oral frenula (HP:0000190)2.44033442
25Supranuclear gaze palsy (HP:0000605)2.43895606
26Fragile skin (HP:0001030)2.42276359
27Spinal rigidity (HP:0003306)2.39921232
28Flat cornea (HP:0007720)2.31815763
29Genu recurvatum (HP:0002816)2.30157146
30Mitral valve prolapse (HP:0001634)2.27577034
31Neurofibrillary tangles (HP:0002185)2.26095381
32Buphthalmos (HP:0000557)2.25246631
33Cerebral inclusion bodies (HP:0100314)2.23398569
34Vertebral compression fractures (HP:0002953)2.22869980
35Increased nuchal translucency (HP:0010880)2.22687034
36Annular pancreas (HP:0001734)2.18418662
37Blue sclerae (HP:0000592)2.16225413
38Atelectasis (HP:0100750)2.16143669
39Subacute progressive viral hepatitis (HP:0006572)2.15963670
40Sacral dimple (HP:0000960)2.15547732
41Ankle contracture (HP:0006466)2.15432935
42Cervical subluxation (HP:0003308)2.14910717
43Upper limb amyotrophy (HP:0009129)2.14729091
44Distal upper limb amyotrophy (HP:0007149)2.14729091
45Hypercortisolism (HP:0001578)2.14436122
46Macroorchidism (HP:0000053)2.13633865
47Achilles tendon contracture (HP:0001771)2.13511582
48Lower limb amyotrophy (HP:0007210)2.11942338
49Abnormality of skeletal muscle fiber size (HP:0012084)2.09882927
50Dilatation of the ascending aorta (HP:0005111)2.08499643
51Asymmetry of the thorax (HP:0001555)2.07822819
52Hyperparathyroidism (HP:0000843)2.07311464
53Neoplasm of the heart (HP:0100544)2.05708277
54Biconcave vertebral bodies (HP:0004586)2.04371025
55Broad metatarsal (HP:0001783)2.02009116
56Enlarged penis (HP:0000040)2.01619047
57Patellar dislocation (HP:0002999)2.01277058
58Fibroma (HP:0010614)2.00973797
59Bronchomalacia (HP:0002780)1.98706355
60Premature rupture of membranes (HP:0001788)1.98557366
61Fibrous tissue neoplasm (HP:0012316)1.97835069
62Hyperextensible skin (HP:0000974)1.97763046
63Thin ribs (HP:0000883)1.97533288
64Centrally nucleated skeletal muscle fibers (HP:0003687)1.96851602
65Mildly elevated creatine phosphokinase (HP:0008180)1.96783439
66Vascular tortuosity (HP:0004948)1.96380614
67Abnormality of the astrocytes (HP:0100707)1.95691362
68Astrocytoma (HP:0009592)1.95691362
69Megalocornea (HP:0000485)1.95547857
70Ulnar bowing (HP:0003031)1.93542035
71Wormian bones (HP:0002645)1.92945672
72Neonatal short-limb short stature (HP:0008921)1.91258304
73Hypoventilation (HP:0002791)1.91048049
74Arnold-Chiari malformation (HP:0002308)1.90939198
75Abnormality of the Achilles tendon (HP:0005109)1.90264115
76Hypercalcemia (HP:0003072)1.89216984
77Heterotopia (HP:0002282)1.88728870
78Broad distal phalanx of finger (HP:0009836)1.88621720
79Abnormality of the distal phalanx of the thumb (HP:0009617)1.88282526
80Trigonocephaly (HP:0000243)1.87452795
81Apathy (HP:0000741)1.87396584
82Difficulty climbing stairs (HP:0003551)1.85065396
83Megalencephaly (HP:0001355)1.84671998
84Joint laxity (HP:0001388)1.84397086
85Arterial tortuosity (HP:0005116)1.83670340
86Amyotrophic lateral sclerosis (HP:0007354)1.83251708
87Precocious puberty (HP:0000826)1.82973424
88Premature skin wrinkling (HP:0100678)1.82058755
89Hyperthyroidism (HP:0000836)1.81648743
90Stridor (HP:0010307)1.81617436
91Partial duplication of the phalanx of hand (HP:0009999)1.81583795
92Urinary urgency (HP:0000012)1.80924056
93Thin bony cortex (HP:0002753)1.80173867
94Abnormality of dentin (HP:0010299)1.79901811
95Congenital glaucoma (HP:0001087)1.79011630
96Obsessive-compulsive behavior (HP:0000722)1.78380432
97Distal lower limb muscle weakness (HP:0009053)1.77501207
98Termporal pattern (HP:0011008)1.76635511
99Insidious onset (HP:0003587)1.76635511
100Abnormality of the diencephalon (HP:0010662)1.76518599
101Abnormality of the aortic arch (HP:0012303)1.76354255
102Obstructive sleep apnea (HP:0002870)1.76292577
103Truncus arteriosus (HP:0001660)1.75649227
104Wrist flexion contracture (HP:0001239)1.75519874
105Difficulty running (HP:0009046)1.75071012
106Metaphyseal cupping (HP:0003021)1.75065085
107Partial duplication of thumb phalanx (HP:0009944)1.74242523
108Deep palmar crease (HP:0006191)1.73571181
109Myokymia (HP:0002411)1.72990301
110Rectal prolapse (HP:0002035)1.72885184
111Abnormality of the phalanges of the hallux (HP:0010057)1.72108746
112Dysmetric saccades (HP:0000641)1.71871916
113Broad thumb (HP:0011304)1.70832480
114Nuclear cataract (HP:0100018)1.70760773
115Increased connective tissue (HP:0009025)1.70273154
116Ependymoma (HP:0002888)1.70225316
117Segmental peripheral demyelination/remyelination (HP:0003481)1.70014338
118Ankle clonus (HP:0011448)1.69990504
119Diminished motivation (HP:0000745)1.68761873
120Coronal craniosynostosis (HP:0004440)1.68661146
121Hand muscle atrophy (HP:0009130)1.68102298
122Abnormality of the thoracic spine (HP:0100711)1.68007864
123Increased variability in muscle fiber diameter (HP:0003557)1.67365679
124Short phalanx of the thumb (HP:0009660)1.66360079
125Aortic aneurysm (HP:0004942)1.65537813
126Wide anterior fontanel (HP:0000260)1.65480653
127Long toe (HP:0010511)1.64702875
128Intellectual disability, profound (HP:0002187)1.64346529
129Hammertoe (HP:0001765)1.63892625
130Papilledema (HP:0001085)1.63715887
131Atrophic scars (HP:0001075)1.63650564
132Shoulder girdle muscle weakness (HP:0003547)1.63559889
133Germ cell neoplasia (HP:0100728)1.63515510
134Urethral obstruction (HP:0000796)1.63497928
135Sleep apnea (HP:0010535)1.62753801
136Aortic dissection (HP:0002647)1.62379449
137Abnormality of the fingertips (HP:0001211)1.62057087
138Bowel incontinence (HP:0002607)1.61683984
139Distal lower limb amyotrophy (HP:0008944)1.61338500
140Pelvic girdle muscle weakness (HP:0003749)1.58095664
141Peritonitis (HP:0002586)1.57984726
142Type 1 muscle fiber predominance (HP:0003803)1.57867574
143Disproportionate tall stature (HP:0001519)1.57720323
144Mitral regurgitation (HP:0001653)1.56692304
145Limb-girdle muscle atrophy (HP:0003797)1.56007052
146Skin tags (HP:0010609)1.55672022
147Aneurysm (HP:0002617)1.55017232
148Hamartoma of the eye (HP:0010568)1.54483589
149Overgrowth (HP:0001548)1.53816500
150Hypoplastic toenails (HP:0001800)1.53058130
151Bicuspid aortic valve (HP:0001647)1.52831001
152High pitched voice (HP:0001620)1.52506712
153Turricephaly (HP:0000262)1.52195303
154Back pain (HP:0003418)1.51912728
155Broad palm (HP:0001169)1.51717783

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB35.20004979
2EEF2K3.89836248
3PKN23.80056005
4MAP3K103.67254875
5SMG13.14199010
6PRPF4B2.94245477
7MARK12.36275485
8PRKD32.35601609
9ICK2.27228375
10TTN2.19642530
11RIPK12.16087354
12SIK21.94171391
13TAOK11.80802635
14PTK61.77620280
15PDGFRA1.72666228
16MAP3K91.71279571
17LATS21.63658216
18IRAK31.63002996
19NTRK11.62286432
20ALK1.60129958
21TYRO31.57417980
22CAMKK11.48184029
23PAK61.47896247
24PRKD21.37266270
25DMPK1.36075928
26LRRK21.33567010
27SCYL21.32881311
28MAP3K111.29211217
29CDK121.26929969
30FGFR41.26306476
31EPHB21.25804378
32ARAF1.21407149
33BMX1.20168675
34KSR11.20116065
35KSR21.18192650
36EPHB11.18154733
37CAMK1G1.17980384
38DDR21.17167634
39SIK11.16481519
40ILK1.14580791
41NTRK21.14119076
42PAK21.13208859
43MTOR1.12683751
44MAP3K71.08791402
45MAP2K31.08623571
46NEK21.06718172
47RET1.02990226
48PAK41.02101913
49TAOK21.02000559
50MINK11.00287756
51DAPK20.99591182
52TESK10.94676210
53EPHA20.94325526
54MAP3K130.93867196
55EPHA40.88652318
56NEK10.88108100
57ERN10.87890359
58MARK20.85105170
59NME20.85000804
60LATS10.84886141
61BRAF0.84266919
62MAP3K10.82249282
63PRKCH0.81472823
64PDPK10.81229809
65RPS6KL10.81035845
66RPS6KC10.81035845
67LMTK20.79286763
68HIPK20.78920479
69CDK60.77237937
70UHMK10.74471497
71PDGFRB0.72445379
72PHKG10.72009248
73PHKG20.72009248
74RPS6KA20.71253258
75FGFR10.70898737
76DYRK1B0.69979431
77CDK40.69146068
78FGFR20.68797014
79MAP3K60.68079485
80RIPK40.67901305
81GRK60.67574403
82MAPK120.65848351
83IRAK20.65781781
84MAP3K40.63425978
85PTK20.62715071
86MOS0.62659701
87CAMK1D0.61800731
88MAP4K10.60064014
89RPS6KA60.58843115
90RPS6KA10.58051748
91CDK150.57650752
92TNK20.56681617
93CDK50.55916057
94SGK30.55798027
95MAP3K30.55734834
96STK380.55090909
97STK110.55084139
98PDK40.54442049
99PDK30.54442049
100MAP3K80.54331500
101RPS6KB20.52516442
102PNCK0.52141681
103CDK180.51918287
104CDK11A0.51913781
105ERBB20.50450802
106CDC70.49158327
107TGFBR10.48831913
108NTRK30.48402052
109PAK30.48044073
110TESK20.47538523
111CDK140.46602497
112PTK2B0.45521875
113MAPK100.44643632
114RPS6KA40.44479262
115MAP2K20.44328104
116PIM20.43179405
117PRKD10.42213244
118PDK10.42167230
119CAMK10.41631706
120CSNK1D0.41427449
121SIK30.41181167
122MAPK40.41099000
123ROCK20.40656702
124AKT20.40532601
125MAPK80.40230518
126ERBB30.39923541
127MAPK90.39759798
128TSSK60.39604103
129BRSK10.39526250
130STK100.39109059
131MAPK70.38925773
132CAMK40.38891897
133CHEK10.37731097
134MAPK110.37261408
135WNK10.37214606
136CDK20.35750599
137CDC42BPA0.35491805
138MAP2K40.35283239
139DAPK10.34441714
140SGK2230.33858280
141SGK4940.33858280

Predicted pathways (KEGG)

RankGene SetZ-score
1Chronic myeloid leukemia_Homo sapiens_hsa052201.95097515
2Glioma_Homo sapiens_hsa052141.77001810
3Prion diseases_Homo sapiens_hsa050201.73185182
4Endometrial cancer_Homo sapiens_hsa052131.61500122
5Non-small cell lung cancer_Homo sapiens_hsa052231.60376447
6VEGF signaling pathway_Homo sapiens_hsa043701.57130949
7Colorectal cancer_Homo sapiens_hsa052101.53434409
8Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.52842749
9Basal cell carcinoma_Homo sapiens_hsa052171.50376083
10mTOR signaling pathway_Homo sapiens_hsa041501.46644688
11Neurotrophin signaling pathway_Homo sapiens_hsa047221.46196532
12Estrogen signaling pathway_Homo sapiens_hsa049151.43487315
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.42838401
14Synaptic vesicle cycle_Homo sapiens_hsa047211.42618829
15Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.41682096
16Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.40811042
17Proteoglycans in cancer_Homo sapiens_hsa052051.37467020
18Axon guidance_Homo sapiens_hsa043601.34879338
19Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.34332416
20Hippo signaling pathway_Homo sapiens_hsa043901.31450621
21Thyroid hormone signaling pathway_Homo sapiens_hsa049191.31238711
22Renal cell carcinoma_Homo sapiens_hsa052111.28968537
23Focal adhesion_Homo sapiens_hsa045101.27956396
24Central carbon metabolism in cancer_Homo sapiens_hsa052301.27913839
25Viral myocarditis_Homo sapiens_hsa054161.27848154
26Nitrogen metabolism_Homo sapiens_hsa009101.25582348
27Small cell lung cancer_Homo sapiens_hsa052221.24664554
28Long-term potentiation_Homo sapiens_hsa047201.24312171
29Notch signaling pathway_Homo sapiens_hsa043301.23866482
30Gap junction_Homo sapiens_hsa045401.21188499
31AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.19870401
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.19798776
33MicroRNAs in cancer_Homo sapiens_hsa052061.17846985
34Bladder cancer_Homo sapiens_hsa052191.16905260
35Pancreatic cancer_Homo sapiens_hsa052121.15967969
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.14945860
37Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.14428945
38ErbB signaling pathway_Homo sapiens_hsa040121.12814954
39Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.11885930
40Aldosterone synthesis and secretion_Homo sapiens_hsa049251.10294152
41Melanogenesis_Homo sapiens_hsa049161.09680110
42Hedgehog signaling pathway_Homo sapiens_hsa043401.09623533
43Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.08794980
44Dilated cardiomyopathy_Homo sapiens_hsa054141.08709601
45Acute myeloid leukemia_Homo sapiens_hsa052211.08346566
46Adherens junction_Homo sapiens_hsa045201.08234948
47Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.07902410
48Oxytocin signaling pathway_Homo sapiens_hsa049211.07078013
49GnRH signaling pathway_Homo sapiens_hsa049121.06773544
50Gastric acid secretion_Homo sapiens_hsa049711.05901074
51Other glycan degradation_Homo sapiens_hsa005111.05535244
52Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.04370166
53Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.04189306
54B cell receptor signaling pathway_Homo sapiens_hsa046621.01463971
55HTLV-I infection_Homo sapiens_hsa051661.01427389
56Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.99567721
57Wnt signaling pathway_Homo sapiens_hsa043100.96933766
58Dopaminergic synapse_Homo sapiens_hsa047280.96802302
59Dorso-ventral axis formation_Homo sapiens_hsa043200.96139345
60T cell receptor signaling pathway_Homo sapiens_hsa046600.95980205
61Cholinergic synapse_Homo sapiens_hsa047250.94999397
62Longevity regulating pathway - mammal_Homo sapiens_hsa042110.94868802
63Insulin signaling pathway_Homo sapiens_hsa049100.94831028
64Olfactory transduction_Homo sapiens_hsa047400.94348999
65Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93734540
66Rap1 signaling pathway_Homo sapiens_hsa040150.91861365
67Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.91553494
68Oocyte meiosis_Homo sapiens_hsa041140.91255560
69Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.91252958
70Type II diabetes mellitus_Homo sapiens_hsa049300.90649193
71Phospholipase D signaling pathway_Homo sapiens_hsa040720.90383022
72mRNA surveillance pathway_Homo sapiens_hsa030150.89526574
73Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.89398665
74Circadian entrainment_Homo sapiens_hsa047130.87098458
75Lysine degradation_Homo sapiens_hsa003100.86662232
76Insulin resistance_Homo sapiens_hsa049310.86334733
77Renin secretion_Homo sapiens_hsa049240.86187954
78Cocaine addiction_Homo sapiens_hsa050300.84875510
79Inositol phosphate metabolism_Homo sapiens_hsa005620.84809799
80MAPK signaling pathway_Homo sapiens_hsa040100.84447491
81Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.84386149
82Amoebiasis_Homo sapiens_hsa051460.83999985
83Amphetamine addiction_Homo sapiens_hsa050310.83968552
84Thyroid cancer_Homo sapiens_hsa052160.83397009
85Platelet activation_Homo sapiens_hsa046110.82664756
86cGMP-PKG signaling pathway_Homo sapiens_hsa040220.82602484
87Prolactin signaling pathway_Homo sapiens_hsa049170.81884755
88Tight junction_Homo sapiens_hsa045300.81883886
89AMPK signaling pathway_Homo sapiens_hsa041520.80861092
90Vibrio cholerae infection_Homo sapiens_hsa051100.80342406
91Regulation of actin cytoskeleton_Homo sapiens_hsa048100.79604300
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.77955233
93Endocytosis_Homo sapiens_hsa041440.77858860
94Glycosaminoglycan degradation_Homo sapiens_hsa005310.77744735
95Pathways in cancer_Homo sapiens_hsa052000.77668380
96Sphingolipid signaling pathway_Homo sapiens_hsa040710.76806926
97Glutamatergic synapse_Homo sapiens_hsa047240.76531139
98Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.75582263
99Toxoplasmosis_Homo sapiens_hsa051450.73524693
100Glucagon signaling pathway_Homo sapiens_hsa049220.73398018
101Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.72746113
102Leukocyte transendothelial migration_Homo sapiens_hsa046700.71934645
103Osteoclast differentiation_Homo sapiens_hsa043800.71726074
104Viral carcinogenesis_Homo sapiens_hsa052030.71331818
105Pentose phosphate pathway_Homo sapiens_hsa000300.70692188
106Choline metabolism in cancer_Homo sapiens_hsa052310.70539126
107Cyanoamino acid metabolism_Homo sapiens_hsa004600.69677324
108HIF-1 signaling pathway_Homo sapiens_hsa040660.69488303
109Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.68885408
110Prostate cancer_Homo sapiens_hsa052150.68845956
111Salivary secretion_Homo sapiens_hsa049700.67648607
112Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.66693519
113Hepatitis B_Homo sapiens_hsa051610.66641520
114Adipocytokine signaling pathway_Homo sapiens_hsa049200.65012632
115ECM-receptor interaction_Homo sapiens_hsa045120.64980768
116Thyroid hormone synthesis_Homo sapiens_hsa049180.63675962
117cAMP signaling pathway_Homo sapiens_hsa040240.63600762
118Toll-like receptor signaling pathway_Homo sapiens_hsa046200.63068161
119Hepatitis C_Homo sapiens_hsa051600.62746883
120Melanoma_Homo sapiens_hsa052180.62724459
121Insulin secretion_Homo sapiens_hsa049110.61298884
122Salmonella infection_Homo sapiens_hsa051320.58448026

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