Rank | Gene Set | Z-score |
---|---|---|
1 | layer formation in cerebral cortex (GO:0021819) | 4.69111093 |
2 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.87031076 |
3 | peptidyl-lysine dimethylation (GO:0018027) | 3.87020900 |
4 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.77880613 |
5 | cell-cell junction maintenance (GO:0045217) | 3.73387037 |
6 | negative regulation of cell size (GO:0045792) | 3.71629122 |
7 | regulation of early endosome to late endosome transport (GO:2000641) | 3.71051408 |
8 | pre-miRNA processing (GO:0031054) | 3.50847414 |
9 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.50676737 |
10 | glial cell proliferation (GO:0014009) | 3.47288847 |
11 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.44484365 |
12 | protein retention in ER lumen (GO:0006621) | 3.43179901 |
13 | establishment of nucleus localization (GO:0040023) | 3.40911239 |
14 | locomotory exploration behavior (GO:0035641) | 3.40559100 |
15 | cerebellar granule cell differentiation (GO:0021707) | 3.38608671 |
16 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.36779174 |
17 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.31542856 |
18 | apoptotic process involved in morphogenesis (GO:0060561) | 3.27413704 |
19 | dendritic spine morphogenesis (GO:0060997) | 3.24155913 |
20 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.22758550 |
21 | adherens junction assembly (GO:0034333) | 3.16526033 |
22 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.12421245 |
23 | plasma membrane repair (GO:0001778) | 3.10065608 |
24 | positive regulation of histone deacetylation (GO:0031065) | 3.08222522 |
25 | protein-DNA complex disassembly (GO:0032986) | 3.04862520 |
26 | nucleosome disassembly (GO:0006337) | 3.04862520 |
27 | maternal placenta development (GO:0001893) | 3.04647014 |
28 | stress fiber assembly (GO:0043149) | 3.04333883 |
29 | negative regulation of catenin import into nucleus (GO:0035414) | 3.01060411 |
30 | glutamate secretion (GO:0014047) | 3.00962443 |
31 | camera-type eye morphogenesis (GO:0048593) | 2.99845945 |
32 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.99096274 |
33 | protein targeting to plasma membrane (GO:0072661) | 2.98695739 |
34 | positive regulation of synapse maturation (GO:0090129) | 2.95810104 |
35 | synaptic vesicle maturation (GO:0016188) | 2.95766364 |
36 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.95029283 |
37 | negative regulation of fatty acid transport (GO:2000192) | 2.94605689 |
38 | hippo signaling (GO:0035329) | 2.94029944 |
39 | regulation of ARF GTPase activity (GO:0032312) | 2.93254349 |
40 | mRNA stabilization (GO:0048255) | 2.92864794 |
41 | RNA stabilization (GO:0043489) | 2.92864794 |
42 | activation of Rac GTPase activity (GO:0032863) | 2.91096918 |
43 | heterochromatin organization (GO:0070828) | 2.90700179 |
44 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.89526849 |
45 | cell migration in hindbrain (GO:0021535) | 2.87152350 |
46 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.87111655 |
47 | peptidyl-arginine methylation (GO:0018216) | 2.86440662 |
48 | peptidyl-arginine N-methylation (GO:0035246) | 2.86440662 |
49 | cellular potassium ion homeostasis (GO:0030007) | 2.84382032 |
50 | corticosteroid receptor signaling pathway (GO:0031958) | 2.81400064 |
51 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.81224461 |
52 | negative regulation of RNA splicing (GO:0033119) | 2.81145447 |
53 | activation of MAPKKK activity (GO:0000185) | 2.80722992 |
54 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.79376482 |
55 | positive regulation of RNA splicing (GO:0033120) | 2.77310054 |
56 | synaptic vesicle exocytosis (GO:0016079) | 2.74212504 |
57 | polarized epithelial cell differentiation (GO:0030859) | 2.74002042 |
58 | regulation of synapse structural plasticity (GO:0051823) | 2.73856569 |
59 | embryonic foregut morphogenesis (GO:0048617) | 2.73682840 |
60 | DNA unwinding involved in DNA replication (GO:0006268) | 2.72336227 |
61 | regulation of hippo signaling (GO:0035330) | 2.72007973 |
62 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.71293713 |
63 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.70803173 |
64 | NLS-bearing protein import into nucleus (GO:0006607) | 2.70612975 |
65 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.70439335 |
66 | mannose metabolic process (GO:0006013) | 2.69986147 |
67 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.69719860 |
68 | COPI coating of Golgi vesicle (GO:0048205) | 2.68702424 |
69 | Golgi transport vesicle coating (GO:0048200) | 2.68702424 |
70 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.67656702 |
71 | atrioventricular valve morphogenesis (GO:0003181) | 2.67563066 |
72 | cell-substrate adherens junction assembly (GO:0007045) | 2.66996828 |
73 | focal adhesion assembly (GO:0048041) | 2.66996828 |
74 | semaphorin-plexin signaling pathway (GO:0071526) | 2.66909069 |
75 | response to parathyroid hormone (GO:0071107) | 2.66609517 |
76 | negative regulation of microtubule polymerization (GO:0031115) | 2.66293244 |
77 | regulation of translational fidelity (GO:0006450) | 2.66154877 |
78 | basement membrane organization (GO:0071711) | 2.65993737 |
79 | sodium ion export (GO:0071436) | 2.65393543 |
80 | regulation of translational termination (GO:0006449) | 2.63615655 |
81 | convergent extension (GO:0060026) | 2.63149482 |
82 | positive regulation of dendrite morphogenesis (GO:0050775) | 2.60985143 |
83 | dopamine receptor signaling pathway (GO:0007212) | 2.60038913 |
84 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.59190842 |
85 | modulation by virus of host morphology or physiology (GO:0019048) | 2.58603412 |
86 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.58190629 |
87 | cell junction maintenance (GO:0034331) | 2.57878814 |
88 | clathrin coat assembly (GO:0048268) | 2.55543410 |
89 | neuromuscular process controlling balance (GO:0050885) | 2.55537322 |
90 | gastrulation with mouth forming second (GO:0001702) | 2.55473976 |
91 | cerebellar Purkinje cell layer development (GO:0021680) | 2.54959979 |
92 | endothelial cell chemotaxis (GO:0035767) | 2.50954104 |
93 | positive regulation of protein dephosphorylation (GO:0035307) | 2.50176038 |
94 | neural tube development (GO:0021915) | 2.49312448 |
95 | apoptotic process involved in development (GO:1902742) | 2.48902262 |
96 | positive regulation of fibroblast migration (GO:0010763) | 2.48590358 |
97 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.48046759 |
98 | negative regulation of mRNA processing (GO:0050686) | 2.47748733 |
99 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.47530630 |
100 | collecting duct development (GO:0072044) | 2.45706842 |
101 | skeletal muscle organ development (GO:0060538) | 2.42946207 |
102 | cell communication by electrical coupling (GO:0010644) | 2.42679040 |
103 | modulation by symbiont of host cellular process (GO:0044068) | 2.42074449 |
104 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.41855281 |
105 | cortical actin cytoskeleton organization (GO:0030866) | 2.41485689 |
106 | cellular response to catecholamine stimulus (GO:0071870) | 2.41113574 |
107 | cellular response to monoamine stimulus (GO:0071868) | 2.41113574 |
108 | barbed-end actin filament capping (GO:0051016) | 2.41047645 |
109 | cochlea morphogenesis (GO:0090103) | 2.40719703 |
110 | negative regulation of mRNA metabolic process (GO:1903312) | 2.40609704 |
111 | activation of protein kinase A activity (GO:0034199) | 2.40056253 |
112 | cell-substrate junction assembly (GO:0007044) | 2.39807175 |
113 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.39627447 |
114 | dendrite morphogenesis (GO:0048813) | 2.39190172 |
115 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.38997036 |
116 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.38268146 |
117 | axon extension (GO:0048675) | 2.37989540 |
118 | eye morphogenesis (GO:0048592) | 2.37409958 |
119 | respiratory system process (GO:0003016) | 2.36817041 |
120 | vocalization behavior (GO:0071625) | 2.36309761 |
121 | modulation by virus of host process (GO:0019054) | 2.34571452 |
122 | regulation of ARF protein signal transduction (GO:0032012) | 2.34457688 |
123 | exploration behavior (GO:0035640) | 2.34099945 |
124 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.34069914 |
125 | skin morphogenesis (GO:0043589) | 2.33457597 |
126 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.33091619 |
127 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.32813456 |
128 | axon extension involved in axon guidance (GO:0048846) | 2.32609708 |
129 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.32609708 |
130 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.32248592 |
131 | cell migration involved in heart development (GO:0060973) | 2.32017084 |
132 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.31834066 |
133 | response to laminar fluid shear stress (GO:0034616) | 2.31796741 |
134 | signal complex assembly (GO:0007172) | 2.31666087 |
135 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.31506900 |
136 | negative regulation of nucleotide catabolic process (GO:0030812) | 2.30835496 |
137 | neuronal ion channel clustering (GO:0045161) | 2.30807809 |
138 | protein localization to endosome (GO:0036010) | 2.29848573 |
139 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.29217725 |
140 | regulation of chromatin binding (GO:0035561) | 2.28863465 |
141 | regulation of establishment of planar polarity (GO:0090175) | 2.28228811 |
142 | peptidyl-threonine modification (GO:0018210) | 2.27845417 |
143 | cardiac myofibril assembly (GO:0055003) | 2.27578838 |
144 | negative regulation of organelle assembly (GO:1902116) | 2.27476251 |
145 | protein heterotrimerization (GO:0070208) | 2.27162185 |
146 | neuron projection extension (GO:1990138) | 2.26929439 |
147 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.26597891 |
148 | peptidyl-threonine phosphorylation (GO:0018107) | 2.26201200 |
149 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.25474777 |
150 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.25373803 |
151 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.25131850 |
152 | positive regulation of axon extension (GO:0045773) | 2.24851270 |
153 | regulation of mRNA stability (GO:0043488) | 2.24718737 |
154 | negative regulation of histone methylation (GO:0031061) | 2.24453788 |
155 | receptor catabolic process (GO:0032801) | 2.24305420 |
156 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.23517653 |
157 | activation of JUN kinase activity (GO:0007257) | 2.21411675 |
158 | dosage compensation (GO:0007549) | 2.20145508 |
159 | body morphogenesis (GO:0010171) | 2.19929616 |
160 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 2.19283824 |
161 | negative regulation of heart growth (GO:0061117) | 2.19283824 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MYC_22102868_ChIP-Seq_BL_Human | 3.55556206 |
2 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.45783588 |
3 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 3.01579589 |
4 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.99515664 |
5 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.88686259 |
6 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.88486294 |
7 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.79472410 |
8 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.75056460 |
9 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.72577229 |
10 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.71389068 |
11 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.52080606 |
12 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.52006844 |
13 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.40590865 |
14 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.39789477 |
15 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 2.39295228 |
16 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 2.35941038 |
17 | * LXR_22292898_ChIP-Seq_THP-1_Human | 2.30326180 |
18 | KDM2B_26808549_Chip-Seq_K562_Human | 2.28137413 |
19 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.26510667 |
20 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 2.26275296 |
21 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.21429324 |
22 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.18211465 |
23 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 2.09395386 |
24 | * ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.08274463 |
25 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 2.00844616 |
26 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.92710504 |
27 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.90248064 |
28 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.89932667 |
29 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.89345136 |
30 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.83311746 |
31 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.72683974 |
32 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.69958542 |
33 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.68527538 |
34 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.63221126 |
35 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.62111705 |
36 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.61229509 |
37 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.59463239 |
38 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.58393321 |
39 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.56665662 |
40 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.56602302 |
41 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.54066356 |
42 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.51101663 |
43 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.49486277 |
44 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.48080014 |
45 | UTX_26944678_Chip-Seq_JUKART_Human | 1.45802347 |
46 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.43748876 |
47 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.40883909 |
48 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.39017583 |
49 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.36535282 |
50 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.35325150 |
51 | MAF_26560356_Chip-Seq_TH1_Human | 1.35127320 |
52 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.33901865 |
53 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.32567924 |
54 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.29969965 |
55 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.29228625 |
56 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.27610087 |
57 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.26966547 |
58 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.26813031 |
59 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.25678470 |
60 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.25007752 |
61 | * TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.24922205 |
62 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.24034703 |
63 | P68_20966046_ChIP-Seq_HELA_Human | 1.23406538 |
64 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.21286371 |
65 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.21043864 |
66 | ATF3_27146783_Chip-Seq_COLON_Human | 1.20763420 |
67 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.20397934 |
68 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.19255181 |
69 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.18830243 |
70 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.16828912 |
71 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.16053779 |
72 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.15695354 |
73 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.15527732 |
74 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.15467351 |
75 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.14913096 |
76 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.14799468 |
77 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.14038231 |
78 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.13365786 |
79 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.12619643 |
80 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.12615898 |
81 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.12615898 |
82 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.12599763 |
83 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.10420254 |
84 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.09718938 |
85 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.09597168 |
86 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.09452922 |
87 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.09357716 |
88 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.08990191 |
89 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.07962562 |
90 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.07632399 |
91 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.07421970 |
92 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.07088635 |
93 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.06815849 |
94 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.03722749 |
95 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 1.03238118 |
96 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.03004513 |
97 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.02866465 |
98 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.02019779 |
99 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.01737214 |
100 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.01303310 |
101 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.01002292 |
102 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.00332858 |
103 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.00279589 |
104 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.00224832 |
105 | * SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.00207606 |
106 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.00148829 |
107 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.00138752 |
108 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.98857371 |
109 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.97155320 |
110 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.95937724 |
111 | * SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 0.95539961 |
112 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.95334493 |
113 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.95220479 |
114 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.95066586 |
115 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.94710712 |
116 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.94710712 |
117 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.94254039 |
118 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.94227512 |
119 | MAF_26560356_Chip-Seq_TH2_Human | 0.94107781 |
120 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.92788122 |
121 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.90486918 |
122 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.89901684 |
123 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.89845778 |
124 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.89560749 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 4.38607173 |
2 | MP0004859_abnormal_synaptic_plasticity | 3.37473573 |
3 | MP0000537_abnormal_urethra_morphology | 3.22204801 |
4 | MP0005076_abnormal_cell_differentiation | 2.86204741 |
5 | MP0009053_abnormal_anal_canal | 2.53474474 |
6 | MP0005409_darkened_coat_color | 2.42875683 |
7 | MP0005623_abnormal_meninges_morphology | 2.36420343 |
8 | MP0008961_abnormal_basal_metabolism | 2.23604212 |
9 | MP0000733_abnormal_muscle_development | 2.18146818 |
10 | MP0010352_gastrointestinal_tract_polyps | 2.17359366 |
11 | MP0010234_abnormal_vibrissa_follicle | 2.16563835 |
12 | MP0010030_abnormal_orbit_morphology | 2.12987061 |
13 | MP0004858_abnormal_nervous_system | 2.07850722 |
14 | MP0001849_ear_inflammation | 2.00761129 |
15 | MP0005257_abnormal_intraocular_pressure | 1.96851099 |
16 | MP0003115_abnormal_respiratory_system | 1.92020678 |
17 | MP0003300_gastrointestinal_ulcer | 1.91104738 |
18 | MP0000566_synostosis | 1.91087208 |
19 | MP0000534_abnormal_ureter_morphology | 1.89291812 |
20 | MP0003303_peritoneal_inflammation | 1.87972377 |
21 | MP0000678_abnormal_parathyroid_gland | 1.86343437 |
22 | MP0002234_abnormal_pharynx_morphology | 1.84636360 |
23 | MP0004233_abnormal_muscle_weight | 1.83801452 |
24 | MP0009379_abnormal_foot_pigmentation | 1.81712206 |
25 | MP0003385_abnormal_body_wall | 1.79065557 |
26 | MP0001348_abnormal_lacrimal_gland | 1.78036206 |
27 | MP0005503_abnormal_tendon_morphology | 1.74906853 |
28 | MP0005058_abnormal_lysosome_morphology | 1.67512203 |
29 | MP0009278_abnormal_bone_marrow | 1.67460590 |
30 | MP0005451_abnormal_body_composition | 1.57867550 |
31 | MP0005187_abnormal_penis_morphology | 1.56124669 |
32 | MP0000751_myopathy | 1.49900533 |
33 | MP0002089_abnormal_postnatal_growth/wei | 1.49541879 |
34 | MP0004197_abnormal_fetal_growth/weight/ | 1.48782687 |
35 | MP0000428_abnormal_craniofacial_morphol | 1.48230413 |
36 | MP0003942_abnormal_urinary_system | 1.46092252 |
37 | MP0003123_paternal_imprinting | 1.46055216 |
38 | MP0003119_abnormal_digestive_system | 1.43137210 |
39 | MP0003879_abnormal_hair_cell | 1.39165758 |
40 | MP0003283_abnormal_digestive_organ | 1.38925765 |
41 | MP0005666_abnormal_adipose_tissue | 1.33252157 |
42 | MP0004185_abnormal_adipocyte_glucose | 1.31727301 |
43 | MP0003635_abnormal_synaptic_transmissio | 1.29436635 |
44 | MP0008260_abnormal_autophagy | 1.27522311 |
45 | MP0002084_abnormal_developmental_patter | 1.26537817 |
46 | MP0003861_abnormal_nervous_system | 1.25683935 |
47 | MP0008770_decreased_survivor_rate | 1.24125423 |
48 | MP0003634_abnormal_glial_cell | 1.24102893 |
49 | MP0008569_lethality_at_weaning | 1.23462688 |
50 | MP0003566_abnormal_cell_adhesion | 1.22927830 |
51 | MP0004808_abnormal_hematopoietic_stem | 1.22088103 |
52 | MP0005508_abnormal_skeleton_morphology | 1.20900124 |
53 | MP0000778_abnormal_nervous_system | 1.20154613 |
54 | MP0001730_embryonic_growth_arrest | 1.19400344 |
55 | MP0003091_abnormal_cell_migration | 1.18883014 |
56 | MP0004087_abnormal_muscle_fiber | 1.18521810 |
57 | MP0003279_aneurysm | 1.17228480 |
58 | MP0001346_abnormal_lacrimal_gland | 1.16857994 |
59 | MP0000569_abnormal_digit_pigmentation | 1.16040898 |
60 | MP0006054_spinal_hemorrhage | 1.15880066 |
61 | MP0003453_abnormal_keratinocyte_physiol | 1.15269974 |
62 | MP0010630_abnormal_cardiac_muscle | 1.13719837 |
63 | MP0002085_abnormal_embryonic_tissue | 1.13668117 |
64 | MP0002932_abnormal_joint_morphology | 1.13566393 |
65 | MP0000747_muscle_weakness | 1.12848646 |
66 | MP0002282_abnormal_trachea_morphology | 1.12820218 |
67 | MP0003122_maternal_imprinting | 1.12731120 |
68 | MP0004811_abnormal_neuron_physiology | 1.12419125 |
69 | MP0009672_abnormal_birth_weight | 1.11929835 |
70 | MP0003567_abnormal_fetal_cardiomyocyte | 1.10559734 |
71 | MP0002925_abnormal_cardiovascular_devel | 1.09294077 |
72 | MP0008438_abnormal_cutaneous_collagen | 1.08181587 |
73 | MP0003935_abnormal_craniofacial_develop | 1.07887342 |
74 | MP0003172_abnormal_lysosome_physiology | 1.07309634 |
75 | MP0004510_myositis | 1.06860965 |
76 | MP0000350_abnormal_cell_proliferation | 1.04953691 |
77 | MP0002063_abnormal_learning/memory/cond | 1.04772486 |
78 | MP0000767_abnormal_smooth_muscle | 1.02338633 |
79 | MP0002653_abnormal_ependyma_morphology | 1.01439661 |
80 | MP0009780_abnormal_chondrocyte_physiolo | 1.00754643 |
81 | MP0001958_emphysema | 0.99762600 |
82 | MP0002088_abnormal_embryonic_growth/wei | 0.99446981 |
83 | MP0003984_embryonic_growth_retardation | 0.98282998 |
84 | MP0005380_embryogenesis_phenotype | 0.98082614 |
85 | MP0001672_abnormal_embryogenesis/_devel | 0.98082614 |
86 | MP0002086_abnormal_extraembryonic_tissu | 0.97332196 |
87 | MP0003329_amyloid_beta_deposits | 0.96453488 |
88 | MP0009384_cardiac_valve_regurgitation | 0.94466273 |
89 | MP0000681_abnormal_thyroid_gland | 0.94259320 |
90 | MP0001697_abnormal_embryo_size | 0.93793563 |
91 | MP0005423_abnormal_somatic_nervous | 0.92133334 |
92 | MP0002081_perinatal_lethality | 0.91868290 |
93 | MP0005248_abnormal_Harderian_gland | 0.91365343 |
94 | MP0000579_abnormal_nail_morphology | 0.88923496 |
95 | * MP0002080_prenatal_lethality | 0.88859522 |
96 | MP0002152_abnormal_brain_morphology | 0.88657062 |
97 | MP0002116_abnormal_craniofacial_bone | 0.88607741 |
98 | MP0003111_abnormal_nucleus_morphology | 0.87310132 |
99 | MP0000759_abnormal_skeletal_muscle | 0.87140721 |
100 | MP0002396_abnormal_hematopoietic_system | 0.86993569 |
101 | MP0002092_abnormal_eye_morphology | 0.86101317 |
102 | MP0001299_abnormal_eye_distance/ | 0.85868577 |
103 | MP0002249_abnormal_larynx_morphology | 0.85815857 |
104 | MP0003755_abnormal_palate_morphology | 0.84671854 |
105 | MP0000266_abnormal_heart_morphology | 0.84156993 |
106 | MP0000750_abnormal_muscle_regeneration | 0.83983693 |
107 | MP0005275_abnormal_skin_tensile | 0.83252195 |
108 | MP0000003_abnormal_adipose_tissue | 0.83071989 |
109 | MP0004130_abnormal_muscle_cell | 0.82941351 |
110 | MP0002877_abnormal_melanocyte_morpholog | 0.82711202 |
111 | MP0004272_abnormal_basement_membrane | 0.82417056 |
112 | MP0000049_abnormal_middle_ear | 0.82167647 |
113 | MP0009840_abnormal_foam_cell | 0.81662473 |
114 | MP0002060_abnormal_skin_morphology | 0.81444748 |
115 | MP0005023_abnormal_wound_healing | 0.80401405 |
116 | MP0004270_analgesia | 0.79875484 |
117 | MP0001784_abnormal_fluid_regulation | 0.79840070 |
118 | MP0000604_amyloidosis | 0.79616083 |
119 | MP0009703_decreased_birth_body | 0.79283782 |
120 | MP0006138_congestive_heart_failure | 0.78848501 |
121 | MP0009250_abnormal_appendicular_skeleto | 0.78706839 |
122 | MP0002896_abnormal_bone_mineralization | 0.78689357 |
123 | MP0005670_abnormal_white_adipose | 0.78217477 |
124 | MP0002697_abnormal_eye_size | 0.77688304 |
125 | MP0003121_genomic_imprinting | 0.76943197 |
126 | MP0003690_abnormal_glial_cell | 0.76846372 |
127 | MP0002114_abnormal_axial_skeleton | 0.76551110 |
128 | MP0001915_intracranial_hemorrhage | 0.76480726 |
129 | MP0000955_abnormal_spinal_cord | 0.75963250 |
130 | MP0003938_abnormal_ear_development | 0.75671635 |
131 | MP0000762_abnormal_tongue_morphology | 0.75613039 |
132 | MP0001502_abnormal_circadian_rhythm | 0.74402967 |
133 | MP0002108_abnormal_muscle_morphology | 0.74294413 |
134 | MP0005375_adipose_tissue_phenotype | 0.72881446 |
135 | MP0000858_altered_metastatic_potential | 0.72873551 |
136 | MP0002064_seizures | 0.70931470 |
137 | MP0005390_skeleton_phenotype | 0.69017914 |
138 | MP0004084_abnormal_cardiac_muscle | 0.68919782 |
139 | MP0000920_abnormal_myelination | 0.68469419 |
140 | MP0002998_abnormal_bone_remodeling | 0.68116493 |
141 | MP0005621_abnormal_cell_physiology | 0.67347524 |
142 | MP0004947_skin_inflammation | 0.67214403 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperacusis (HP:0010780) | 4.17709209 |
2 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 3.78745880 |
3 | Short 4th metacarpal (HP:0010044) | 3.78745880 |
4 | Shallow orbits (HP:0000586) | 3.77552286 |
5 | Abnormality of the 4th metacarpal (HP:0010012) | 3.29393742 |
6 | Renal duplication (HP:0000075) | 3.28961757 |
7 | Protrusio acetabuli (HP:0003179) | 3.23446059 |
8 | Insomnia (HP:0100785) | 3.11458382 |
9 | Elfin facies (HP:0004428) | 3.00987764 |
10 | Overriding aorta (HP:0002623) | 2.96443814 |
11 | Renovascular hypertension (HP:0100817) | 2.89033181 |
12 | Pointed chin (HP:0000307) | 2.86467291 |
13 | Broad face (HP:0000283) | 2.71703745 |
14 | Cerebral aneurysm (HP:0004944) | 2.68003044 |
15 | Bladder diverticulum (HP:0000015) | 2.63153968 |
16 | Ankyloglossia (HP:0010296) | 2.60641206 |
17 | Abnormality of the lower motor neuron (HP:0002366) | 2.58260861 |
18 | Hallux valgus (HP:0001822) | 2.57752803 |
19 | Deviation of the hallux (HP:0010051) | 2.57450642 |
20 | Long palpebral fissure (HP:0000637) | 2.57168595 |
21 | Bowel diverticulosis (HP:0005222) | 2.55436807 |
22 | Increased density of long bones (HP:0006392) | 2.54802636 |
23 | Lymphangioma (HP:0100764) | 2.45125556 |
24 | Abnormality of oral frenula (HP:0000190) | 2.44033442 |
25 | Supranuclear gaze palsy (HP:0000605) | 2.43895606 |
26 | Fragile skin (HP:0001030) | 2.42276359 |
27 | Spinal rigidity (HP:0003306) | 2.39921232 |
28 | Flat cornea (HP:0007720) | 2.31815763 |
29 | Genu recurvatum (HP:0002816) | 2.30157146 |
30 | Mitral valve prolapse (HP:0001634) | 2.27577034 |
31 | Neurofibrillary tangles (HP:0002185) | 2.26095381 |
32 | Buphthalmos (HP:0000557) | 2.25246631 |
33 | Cerebral inclusion bodies (HP:0100314) | 2.23398569 |
34 | Vertebral compression fractures (HP:0002953) | 2.22869980 |
35 | Increased nuchal translucency (HP:0010880) | 2.22687034 |
36 | Annular pancreas (HP:0001734) | 2.18418662 |
37 | Blue sclerae (HP:0000592) | 2.16225413 |
38 | Atelectasis (HP:0100750) | 2.16143669 |
39 | Subacute progressive viral hepatitis (HP:0006572) | 2.15963670 |
40 | Sacral dimple (HP:0000960) | 2.15547732 |
41 | Ankle contracture (HP:0006466) | 2.15432935 |
42 | Cervical subluxation (HP:0003308) | 2.14910717 |
43 | Upper limb amyotrophy (HP:0009129) | 2.14729091 |
44 | Distal upper limb amyotrophy (HP:0007149) | 2.14729091 |
45 | Hypercortisolism (HP:0001578) | 2.14436122 |
46 | Macroorchidism (HP:0000053) | 2.13633865 |
47 | Achilles tendon contracture (HP:0001771) | 2.13511582 |
48 | Lower limb amyotrophy (HP:0007210) | 2.11942338 |
49 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.09882927 |
50 | Dilatation of the ascending aorta (HP:0005111) | 2.08499643 |
51 | Asymmetry of the thorax (HP:0001555) | 2.07822819 |
52 | Hyperparathyroidism (HP:0000843) | 2.07311464 |
53 | Neoplasm of the heart (HP:0100544) | 2.05708277 |
54 | Biconcave vertebral bodies (HP:0004586) | 2.04371025 |
55 | Broad metatarsal (HP:0001783) | 2.02009116 |
56 | Enlarged penis (HP:0000040) | 2.01619047 |
57 | Patellar dislocation (HP:0002999) | 2.01277058 |
58 | Fibroma (HP:0010614) | 2.00973797 |
59 | Bronchomalacia (HP:0002780) | 1.98706355 |
60 | Premature rupture of membranes (HP:0001788) | 1.98557366 |
61 | Fibrous tissue neoplasm (HP:0012316) | 1.97835069 |
62 | Hyperextensible skin (HP:0000974) | 1.97763046 |
63 | Thin ribs (HP:0000883) | 1.97533288 |
64 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.96851602 |
65 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.96783439 |
66 | Vascular tortuosity (HP:0004948) | 1.96380614 |
67 | Abnormality of the astrocytes (HP:0100707) | 1.95691362 |
68 | Astrocytoma (HP:0009592) | 1.95691362 |
69 | Megalocornea (HP:0000485) | 1.95547857 |
70 | Ulnar bowing (HP:0003031) | 1.93542035 |
71 | Wormian bones (HP:0002645) | 1.92945672 |
72 | Neonatal short-limb short stature (HP:0008921) | 1.91258304 |
73 | Hypoventilation (HP:0002791) | 1.91048049 |
74 | Arnold-Chiari malformation (HP:0002308) | 1.90939198 |
75 | Abnormality of the Achilles tendon (HP:0005109) | 1.90264115 |
76 | Hypercalcemia (HP:0003072) | 1.89216984 |
77 | Heterotopia (HP:0002282) | 1.88728870 |
78 | Broad distal phalanx of finger (HP:0009836) | 1.88621720 |
79 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.88282526 |
80 | Trigonocephaly (HP:0000243) | 1.87452795 |
81 | Apathy (HP:0000741) | 1.87396584 |
82 | Difficulty climbing stairs (HP:0003551) | 1.85065396 |
83 | Megalencephaly (HP:0001355) | 1.84671998 |
84 | Joint laxity (HP:0001388) | 1.84397086 |
85 | Arterial tortuosity (HP:0005116) | 1.83670340 |
86 | Amyotrophic lateral sclerosis (HP:0007354) | 1.83251708 |
87 | Precocious puberty (HP:0000826) | 1.82973424 |
88 | Premature skin wrinkling (HP:0100678) | 1.82058755 |
89 | Hyperthyroidism (HP:0000836) | 1.81648743 |
90 | Stridor (HP:0010307) | 1.81617436 |
91 | Partial duplication of the phalanx of hand (HP:0009999) | 1.81583795 |
92 | Urinary urgency (HP:0000012) | 1.80924056 |
93 | Thin bony cortex (HP:0002753) | 1.80173867 |
94 | Abnormality of dentin (HP:0010299) | 1.79901811 |
95 | Congenital glaucoma (HP:0001087) | 1.79011630 |
96 | Obsessive-compulsive behavior (HP:0000722) | 1.78380432 |
97 | Distal lower limb muscle weakness (HP:0009053) | 1.77501207 |
98 | Termporal pattern (HP:0011008) | 1.76635511 |
99 | Insidious onset (HP:0003587) | 1.76635511 |
100 | Abnormality of the diencephalon (HP:0010662) | 1.76518599 |
101 | Abnormality of the aortic arch (HP:0012303) | 1.76354255 |
102 | Obstructive sleep apnea (HP:0002870) | 1.76292577 |
103 | Truncus arteriosus (HP:0001660) | 1.75649227 |
104 | Wrist flexion contracture (HP:0001239) | 1.75519874 |
105 | Difficulty running (HP:0009046) | 1.75071012 |
106 | Metaphyseal cupping (HP:0003021) | 1.75065085 |
107 | Partial duplication of thumb phalanx (HP:0009944) | 1.74242523 |
108 | Deep palmar crease (HP:0006191) | 1.73571181 |
109 | Myokymia (HP:0002411) | 1.72990301 |
110 | Rectal prolapse (HP:0002035) | 1.72885184 |
111 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.72108746 |
112 | Dysmetric saccades (HP:0000641) | 1.71871916 |
113 | Broad thumb (HP:0011304) | 1.70832480 |
114 | Nuclear cataract (HP:0100018) | 1.70760773 |
115 | Increased connective tissue (HP:0009025) | 1.70273154 |
116 | Ependymoma (HP:0002888) | 1.70225316 |
117 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.70014338 |
118 | Ankle clonus (HP:0011448) | 1.69990504 |
119 | Diminished motivation (HP:0000745) | 1.68761873 |
120 | Coronal craniosynostosis (HP:0004440) | 1.68661146 |
121 | Hand muscle atrophy (HP:0009130) | 1.68102298 |
122 | Abnormality of the thoracic spine (HP:0100711) | 1.68007864 |
123 | Increased variability in muscle fiber diameter (HP:0003557) | 1.67365679 |
124 | Short phalanx of the thumb (HP:0009660) | 1.66360079 |
125 | Aortic aneurysm (HP:0004942) | 1.65537813 |
126 | Wide anterior fontanel (HP:0000260) | 1.65480653 |
127 | Long toe (HP:0010511) | 1.64702875 |
128 | Intellectual disability, profound (HP:0002187) | 1.64346529 |
129 | Hammertoe (HP:0001765) | 1.63892625 |
130 | Papilledema (HP:0001085) | 1.63715887 |
131 | Atrophic scars (HP:0001075) | 1.63650564 |
132 | Shoulder girdle muscle weakness (HP:0003547) | 1.63559889 |
133 | Germ cell neoplasia (HP:0100728) | 1.63515510 |
134 | Urethral obstruction (HP:0000796) | 1.63497928 |
135 | Sleep apnea (HP:0010535) | 1.62753801 |
136 | Aortic dissection (HP:0002647) | 1.62379449 |
137 | Abnormality of the fingertips (HP:0001211) | 1.62057087 |
138 | Bowel incontinence (HP:0002607) | 1.61683984 |
139 | Distal lower limb amyotrophy (HP:0008944) | 1.61338500 |
140 | Pelvic girdle muscle weakness (HP:0003749) | 1.58095664 |
141 | Peritonitis (HP:0002586) | 1.57984726 |
142 | Type 1 muscle fiber predominance (HP:0003803) | 1.57867574 |
143 | Disproportionate tall stature (HP:0001519) | 1.57720323 |
144 | Mitral regurgitation (HP:0001653) | 1.56692304 |
145 | Limb-girdle muscle atrophy (HP:0003797) | 1.56007052 |
146 | Skin tags (HP:0010609) | 1.55672022 |
147 | Aneurysm (HP:0002617) | 1.55017232 |
148 | Hamartoma of the eye (HP:0010568) | 1.54483589 |
149 | Overgrowth (HP:0001548) | 1.53816500 |
150 | Hypoplastic toenails (HP:0001800) | 1.53058130 |
151 | Bicuspid aortic valve (HP:0001647) | 1.52831001 |
152 | High pitched voice (HP:0001620) | 1.52506712 |
153 | Turricephaly (HP:0000262) | 1.52195303 |
154 | Back pain (HP:0003418) | 1.51912728 |
155 | Broad palm (HP:0001169) | 1.51717783 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 5.20004979 |
2 | EEF2K | 3.89836248 |
3 | PKN2 | 3.80056005 |
4 | MAP3K10 | 3.67254875 |
5 | SMG1 | 3.14199010 |
6 | PRPF4B | 2.94245477 |
7 | MARK1 | 2.36275485 |
8 | PRKD3 | 2.35601609 |
9 | ICK | 2.27228375 |
10 | TTN | 2.19642530 |
11 | RIPK1 | 2.16087354 |
12 | SIK2 | 1.94171391 |
13 | TAOK1 | 1.80802635 |
14 | PTK6 | 1.77620280 |
15 | PDGFRA | 1.72666228 |
16 | MAP3K9 | 1.71279571 |
17 | LATS2 | 1.63658216 |
18 | IRAK3 | 1.63002996 |
19 | NTRK1 | 1.62286432 |
20 | ALK | 1.60129958 |
21 | TYRO3 | 1.57417980 |
22 | CAMKK1 | 1.48184029 |
23 | PAK6 | 1.47896247 |
24 | PRKD2 | 1.37266270 |
25 | DMPK | 1.36075928 |
26 | LRRK2 | 1.33567010 |
27 | SCYL2 | 1.32881311 |
28 | MAP3K11 | 1.29211217 |
29 | CDK12 | 1.26929969 |
30 | FGFR4 | 1.26306476 |
31 | EPHB2 | 1.25804378 |
32 | ARAF | 1.21407149 |
33 | BMX | 1.20168675 |
34 | KSR1 | 1.20116065 |
35 | KSR2 | 1.18192650 |
36 | EPHB1 | 1.18154733 |
37 | CAMK1G | 1.17980384 |
38 | DDR2 | 1.17167634 |
39 | SIK1 | 1.16481519 |
40 | ILK | 1.14580791 |
41 | NTRK2 | 1.14119076 |
42 | PAK2 | 1.13208859 |
43 | MTOR | 1.12683751 |
44 | MAP3K7 | 1.08791402 |
45 | MAP2K3 | 1.08623571 |
46 | NEK2 | 1.06718172 |
47 | RET | 1.02990226 |
48 | PAK4 | 1.02101913 |
49 | TAOK2 | 1.02000559 |
50 | MINK1 | 1.00287756 |
51 | DAPK2 | 0.99591182 |
52 | TESK1 | 0.94676210 |
53 | EPHA2 | 0.94325526 |
54 | MAP3K13 | 0.93867196 |
55 | EPHA4 | 0.88652318 |
56 | NEK1 | 0.88108100 |
57 | ERN1 | 0.87890359 |
58 | MARK2 | 0.85105170 |
59 | NME2 | 0.85000804 |
60 | LATS1 | 0.84886141 |
61 | BRAF | 0.84266919 |
62 | MAP3K1 | 0.82249282 |
63 | PRKCH | 0.81472823 |
64 | PDPK1 | 0.81229809 |
65 | RPS6KC1 | 0.81035845 |
66 | RPS6KL1 | 0.81035845 |
67 | LMTK2 | 0.79286763 |
68 | HIPK2 | 0.78920479 |
69 | CDK6 | 0.77237937 |
70 | UHMK1 | 0.74471497 |
71 | PDGFRB | 0.72445379 |
72 | PHKG2 | 0.72009248 |
73 | PHKG1 | 0.72009248 |
74 | RPS6KA2 | 0.71253258 |
75 | FGFR1 | 0.70898737 |
76 | DYRK1B | 0.69979431 |
77 | CDK4 | 0.69146068 |
78 | FGFR2 | 0.68797014 |
79 | MAP3K6 | 0.68079485 |
80 | RIPK4 | 0.67901305 |
81 | GRK6 | 0.67574403 |
82 | MAPK12 | 0.65848351 |
83 | IRAK2 | 0.65781781 |
84 | MAP3K4 | 0.63425978 |
85 | PTK2 | 0.62715071 |
86 | MOS | 0.62659701 |
87 | CAMK1D | 0.61800731 |
88 | MAP4K1 | 0.60064014 |
89 | RPS6KA6 | 0.58843115 |
90 | RPS6KA1 | 0.58051748 |
91 | CDK15 | 0.57650752 |
92 | TNK2 | 0.56681617 |
93 | CDK5 | 0.55916057 |
94 | SGK3 | 0.55798027 |
95 | MAP3K3 | 0.55734834 |
96 | STK38 | 0.55090909 |
97 | STK11 | 0.55084139 |
98 | PDK3 | 0.54442049 |
99 | PDK4 | 0.54442049 |
100 | MAP3K8 | 0.54331500 |
101 | RPS6KB2 | 0.52516442 |
102 | PNCK | 0.52141681 |
103 | CDK18 | 0.51918287 |
104 | CDK11A | 0.51913781 |
105 | ERBB2 | 0.50450802 |
106 | CDC7 | 0.49158327 |
107 | TGFBR1 | 0.48831913 |
108 | NTRK3 | 0.48402052 |
109 | PAK3 | 0.48044073 |
110 | TESK2 | 0.47538523 |
111 | CDK14 | 0.46602497 |
112 | PTK2B | 0.45521875 |
113 | MAPK10 | 0.44643632 |
114 | RPS6KA4 | 0.44479262 |
115 | MAP2K2 | 0.44328104 |
116 | PIM2 | 0.43179405 |
117 | PRKD1 | 0.42213244 |
118 | PDK1 | 0.42167230 |
119 | CAMK1 | 0.41631706 |
120 | CSNK1D | 0.41427449 |
121 | SIK3 | 0.41181167 |
122 | MAPK4 | 0.41099000 |
123 | ROCK2 | 0.40656702 |
124 | AKT2 | 0.40532601 |
125 | MAPK8 | 0.40230518 |
126 | ERBB3 | 0.39923541 |
127 | MAPK9 | 0.39759798 |
128 | TSSK6 | 0.39604103 |
129 | BRSK1 | 0.39526250 |
130 | STK10 | 0.39109059 |
131 | MAPK7 | 0.38925773 |
132 | CAMK4 | 0.38891897 |
133 | CHEK1 | 0.37731097 |
134 | MAPK11 | 0.37261408 |
135 | WNK1 | 0.37214606 |
136 | CDK2 | 0.35750599 |
137 | CDC42BPA | 0.35491805 |
138 | MAP2K4 | 0.35283239 |
139 | DAPK1 | 0.34441714 |
140 | SGK223 | 0.33858280 |
141 | SGK494 | 0.33858280 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.95097515 |
2 | Glioma_Homo sapiens_hsa05214 | 1.77001810 |
3 | Prion diseases_Homo sapiens_hsa05020 | 1.73185182 |
4 | Endometrial cancer_Homo sapiens_hsa05213 | 1.61500122 |
5 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.60376447 |
6 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.57130949 |
7 | Colorectal cancer_Homo sapiens_hsa05210 | 1.53434409 |
8 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.52842749 |
9 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.50376083 |
10 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.46644688 |
11 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.46196532 |
12 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.43487315 |
13 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.42838401 |
14 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.42618829 |
15 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.41682096 |
16 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.40811042 |
17 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.37467020 |
18 | Axon guidance_Homo sapiens_hsa04360 | 1.34879338 |
19 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.34332416 |
20 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.31450621 |
21 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.31238711 |
22 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.28968537 |
23 | Focal adhesion_Homo sapiens_hsa04510 | 1.27956396 |
24 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.27913839 |
25 | Viral myocarditis_Homo sapiens_hsa05416 | 1.27848154 |
26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.25582348 |
27 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.24664554 |
28 | Long-term potentiation_Homo sapiens_hsa04720 | 1.24312171 |
29 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.23866482 |
30 | Gap junction_Homo sapiens_hsa04540 | 1.21188499 |
31 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.19870401 |
32 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.19798776 |
33 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.17846985 |
34 | Bladder cancer_Homo sapiens_hsa05219 | 1.16905260 |
35 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.15967969 |
36 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.14945860 |
37 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.14428945 |
38 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.12814954 |
39 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.11885930 |
40 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.10294152 |
41 | Melanogenesis_Homo sapiens_hsa04916 | 1.09680110 |
42 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.09623533 |
43 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.08794980 |
44 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.08709601 |
45 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.08346566 |
46 | Adherens junction_Homo sapiens_hsa04520 | 1.08234948 |
47 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.07902410 |
48 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.07078013 |
49 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.06773544 |
50 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.05901074 |
51 | Other glycan degradation_Homo sapiens_hsa00511 | 1.05535244 |
52 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.04370166 |
53 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.04189306 |
54 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.01463971 |
55 | HTLV-I infection_Homo sapiens_hsa05166 | 1.01427389 |
56 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.99567721 |
57 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.96933766 |
58 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.96802302 |
59 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.96139345 |
60 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.95980205 |
61 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.94999397 |
62 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.94868802 |
63 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.94831028 |
64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.94348999 |
65 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.93734540 |
66 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.91861365 |
67 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.91553494 |
68 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.91255560 |
69 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.91252958 |
70 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.90649193 |
71 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.90383022 |
72 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.89526574 |
73 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.89398665 |
74 | Circadian entrainment_Homo sapiens_hsa04713 | 0.87098458 |
75 | Lysine degradation_Homo sapiens_hsa00310 | 0.86662232 |
76 | Insulin resistance_Homo sapiens_hsa04931 | 0.86334733 |
77 | Renin secretion_Homo sapiens_hsa04924 | 0.86187954 |
78 | Cocaine addiction_Homo sapiens_hsa05030 | 0.84875510 |
79 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.84809799 |
80 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.84447491 |
81 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.84386149 |
82 | Amoebiasis_Homo sapiens_hsa05146 | 0.83999985 |
83 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.83968552 |
84 | Thyroid cancer_Homo sapiens_hsa05216 | 0.83397009 |
85 | Platelet activation_Homo sapiens_hsa04611 | 0.82664756 |
86 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.82602484 |
87 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.81884755 |
88 | Tight junction_Homo sapiens_hsa04530 | 0.81883886 |
89 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.80861092 |
90 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.80342406 |
91 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.79604300 |
92 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.77955233 |
93 | Endocytosis_Homo sapiens_hsa04144 | 0.77858860 |
94 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.77744735 |
95 | Pathways in cancer_Homo sapiens_hsa05200 | 0.77668380 |
96 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.76806926 |
97 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.76531139 |
98 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.75582263 |
99 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.73524693 |
100 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.73398018 |
101 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.72746113 |
102 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.71934645 |
103 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.71726074 |
104 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.71331818 |
105 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.70692188 |
106 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.70539126 |
107 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.69677324 |
108 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.69488303 |
109 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.68885408 |
110 | Prostate cancer_Homo sapiens_hsa05215 | 0.68845956 |
111 | Salivary secretion_Homo sapiens_hsa04970 | 0.67648607 |
112 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.66693519 |
113 | Hepatitis B_Homo sapiens_hsa05161 | 0.66641520 |
114 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.65012632 |
115 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.64980768 |
116 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.63675962 |
117 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.63600762 |
118 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.63068161 |
119 | Hepatitis C_Homo sapiens_hsa05160 | 0.62746883 |
120 | Melanoma_Homo sapiens_hsa05218 | 0.62724459 |
121 | Insulin secretion_Homo sapiens_hsa04911 | 0.61298884 |
122 | Salmonella infection_Homo sapiens_hsa05132 | 0.58448026 |