Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.59079437 |
2 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.36592452 |
3 | regulation of gamma-delta T cell activation (GO:0046643) | 5.16666775 |
4 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.68397327 |
5 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.68397327 |
6 | mannose metabolic process (GO:0006013) | 4.52968696 |
7 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.45648330 |
8 | positive thymic T cell selection (GO:0045059) | 4.08927071 |
9 | B cell receptor signaling pathway (GO:0050853) | 3.96820507 |
10 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.80870069 |
11 | positive regulation of B cell differentiation (GO:0045579) | 3.78178331 |
12 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.77692775 |
13 | positive regulation of histone deacetylation (GO:0031065) | 3.72880581 |
14 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.62145629 |
15 | regulation of B cell differentiation (GO:0045577) | 3.51029515 |
16 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.19917273 |
17 | negative regulation of cell killing (GO:0031342) | 3.18749355 |
18 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.18749355 |
19 | negative regulation of granulocyte differentiation (GO:0030853) | 3.18029933 |
20 | regulation of regulatory T cell differentiation (GO:0045589) | 3.12403993 |
21 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.11099245 |
22 | T cell homeostasis (GO:0043029) | 3.09900198 |
23 | negative regulation of myotube differentiation (GO:0010832) | 3.09296899 |
24 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.09046905 |
25 | creatine metabolic process (GO:0006600) | 3.07984545 |
26 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.07615623 |
27 | regulation of skeletal muscle contraction (GO:0014819) | 3.06763061 |
28 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.03682167 |
29 | positive T cell selection (GO:0043368) | 3.01468842 |
30 | Peyers patch development (GO:0048541) | 2.99433387 |
31 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.99433387 |
32 | histone H3-K4 trimethylation (GO:0080182) | 2.98183317 |
33 | negative regulation of cell size (GO:0045792) | 2.97119853 |
34 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.96527571 |
35 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.96420748 |
36 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.96420748 |
37 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.96420748 |
38 | modulation by symbiont of host immune response (GO:0052553) | 2.96420748 |
39 | positive regulation by symbiont of host defense response (GO:0052509) | 2.96420748 |
40 | modulation by symbiont of host defense response (GO:0052031) | 2.96420748 |
41 | thymic T cell selection (GO:0045061) | 2.94939432 |
42 | positive regulation of fatty acid oxidation (GO:0046321) | 2.92536770 |
43 | leukocyte aggregation (GO:0070486) | 2.91130555 |
44 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.90058810 |
45 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.89635783 |
46 | skeletal muscle contraction (GO:0003009) | 2.88994808 |
47 | cellular response to exogenous dsRNA (GO:0071360) | 2.87179317 |
48 | positive regulation of CREB transcription factor activity (GO:0032793) | 2.83210314 |
49 | T cell selection (GO:0045058) | 2.81736780 |
50 | lymphocyte homeostasis (GO:0002260) | 2.81692189 |
51 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.78535328 |
52 | positive regulation of protein deacetylation (GO:0090312) | 2.77671927 |
53 | negative regulation of phagocytosis (GO:0050765) | 2.72385129 |
54 | NIK/NF-kappaB signaling (GO:0038061) | 2.71736391 |
55 | myeloid dendritic cell activation (GO:0001773) | 2.68552597 |
56 | regulation of granulocyte differentiation (GO:0030852) | 2.68546854 |
57 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.64577658 |
58 | negative thymic T cell selection (GO:0045060) | 2.64452184 |
59 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.62836579 |
60 | response to interleukin-15 (GO:0070672) | 2.61853984 |
61 | response to type I interferon (GO:0034340) | 2.61829022 |
62 | B cell homeostasis (GO:0001782) | 2.61585444 |
63 | cellular response to zinc ion (GO:0071294) | 2.60726397 |
64 | regulation of T cell tolerance induction (GO:0002664) | 2.60064981 |
65 | tolerance induction (GO:0002507) | 2.58419648 |
66 | histone H3-K4 methylation (GO:0051568) | 2.57458708 |
67 | myeloid dendritic cell differentiation (GO:0043011) | 2.57196405 |
68 | regulation of necroptotic process (GO:0060544) | 2.56899430 |
69 | negative T cell selection (GO:0043383) | 2.56388708 |
70 | natural killer cell differentiation (GO:0001779) | 2.56079355 |
71 | oxygen transport (GO:0015671) | 2.54767029 |
72 | positive regulation of granulocyte differentiation (GO:0030854) | 2.54476069 |
73 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.53729105 |
74 | muscle atrophy (GO:0014889) | 2.53673070 |
75 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 2.52451923 |
76 | macrophage activation involved in immune response (GO:0002281) | 2.51605416 |
77 | type I interferon signaling pathway (GO:0060337) | 2.51603009 |
78 | cellular response to type I interferon (GO:0071357) | 2.51603009 |
79 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.51102331 |
80 | defense response to protozoan (GO:0042832) | 2.49336872 |
81 | negative regulation of bone resorption (GO:0045779) | 2.49089976 |
82 | positive regulation of myotube differentiation (GO:0010831) | 2.48997883 |
83 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.48924522 |
84 | regulation of chromatin binding (GO:0035561) | 2.48711298 |
85 | response to protozoan (GO:0001562) | 2.47119524 |
86 | T cell migration (GO:0072678) | 2.46502660 |
87 | positive regulation of Rap GTPase activity (GO:0032854) | 2.46114969 |
88 | histone H3-K36 demethylation (GO:0070544) | 2.45743347 |
89 | B cell proliferation (GO:0042100) | 2.45739968 |
90 | peptidyl-lysine trimethylation (GO:0018023) | 2.45517814 |
91 | immunoglobulin mediated immune response (GO:0016064) | 2.45424580 |
92 | negative regulation of interleukin-8 production (GO:0032717) | 2.43587274 |
93 | germ cell migration (GO:0008354) | 2.42516303 |
94 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.41946830 |
95 | skeletal muscle adaptation (GO:0043501) | 2.40802450 |
96 | leukocyte cell-cell adhesion (GO:0007159) | 2.40677566 |
97 | muscle filament sliding (GO:0030049) | 2.40043206 |
98 | actin-myosin filament sliding (GO:0033275) | 2.40043206 |
99 | hepatocyte apoptotic process (GO:0097284) | 2.39340250 |
100 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.39150460 |
101 | negative regulation of histone methylation (GO:0031061) | 2.38339678 |
102 | negative regulation of fatty acid transport (GO:2000192) | 2.38193473 |
103 | regulation of ARF GTPase activity (GO:0032312) | 2.37909960 |
104 | leukocyte homeostasis (GO:0001776) | 2.37164422 |
105 | regulation of integrin activation (GO:0033623) | 2.36321731 |
106 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.35885564 |
107 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.35885564 |
108 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.35885564 |
109 | gas transport (GO:0015669) | 2.34930996 |
110 | neutrophil activation (GO:0042119) | 2.34454710 |
111 | negative regulation of stress fiber assembly (GO:0051497) | 2.34236421 |
112 | regulation of fatty acid oxidation (GO:0046320) | 2.34119050 |
113 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.34022140 |
114 | germinal center formation (GO:0002467) | 2.33067647 |
115 | regulation of erythrocyte differentiation (GO:0045646) | 2.32873836 |
116 | definitive hemopoiesis (GO:0060216) | 2.32573686 |
117 | regulation of RNA export from nucleus (GO:0046831) | 2.31212502 |
118 | angiogenesis involved in wound healing (GO:0060055) | 2.31200275 |
119 | regulation of histone deacetylation (GO:0031063) | 2.31156947 |
120 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.31105741 |
121 | regulation of histone H3-K27 methylation (GO:0061085) | 2.29523683 |
122 | positive regulation of isotype switching (GO:0045830) | 2.29426781 |
123 | cellular extravasation (GO:0045123) | 2.28041231 |
124 | response to muramyl dipeptide (GO:0032495) | 2.27543439 |
125 | regulation of leukocyte degranulation (GO:0043300) | 2.27436081 |
126 | megakaryocyte development (GO:0035855) | 2.27365889 |
127 | positive regulation of lamellipodium assembly (GO:0010592) | 2.27304664 |
128 | striated muscle atrophy (GO:0014891) | 2.26760546 |
129 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.25841452 |
130 | embryonic hemopoiesis (GO:0035162) | 2.25603937 |
131 | lymph node development (GO:0048535) | 2.25554322 |
132 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.25501609 |
133 | carnitine transmembrane transport (GO:1902603) | 2.24562514 |
134 | interkinetic nuclear migration (GO:0022027) | 2.24262970 |
135 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.23327069 |
136 | detection of bacterium (GO:0016045) | 2.22550099 |
137 | regulation of hydrogen peroxide metabolic process (GO:0010310) | 2.22278208 |
138 | regulation of necrotic cell death (GO:0010939) | 2.21849286 |
139 | cellular response to virus (GO:0098586) | 2.20136621 |
140 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.19605064 |
141 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.19395973 |
142 | growth hormone receptor signaling pathway (GO:0060396) | 2.16867500 |
143 | positive regulation of protein kinase C signaling (GO:0090037) | 2.15310410 |
144 | phospholipid scrambling (GO:0017121) | 2.14338498 |
145 | response to peptidoglycan (GO:0032494) | 2.13411137 |
146 | myofibril assembly (GO:0030239) | 2.13216991 |
147 | endothelial cell chemotaxis (GO:0035767) | 2.12275752 |
148 | carnitine shuttle (GO:0006853) | 2.12240047 |
149 | histone H4 deacetylation (GO:0070933) | 2.09027980 |
150 | regulation of mast cell degranulation (GO:0043304) | 2.07469495 |
151 | modulation by virus of host process (GO:0019054) | 2.07069801 |
152 | glomerular filtration (GO:0003094) | 2.07035104 |
153 | osteoblast development (GO:0002076) | 2.06528391 |
154 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.06365937 |
155 | detection of other organism (GO:0098543) | 2.05572085 |
156 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.04842206 |
157 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.04437372 |
158 | atrioventricular valve morphogenesis (GO:0003181) | 2.01933951 |
159 | histone lysine demethylation (GO:0070076) | 2.01809357 |
160 | renal filtration (GO:0097205) | 2.01469485 |
161 | negative regulation of viral release from host cell (GO:1902187) | 2.01118849 |
162 | activation of JUN kinase activity (GO:0007257) | 2.01113535 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 4.23171645 |
2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.20336339 |
3 | MYC_22102868_ChIP-Seq_BL_Human | 4.17495373 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.17491794 |
5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.63536317 |
6 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.26057755 |
7 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.25659065 |
8 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.01460968 |
9 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.81530396 |
10 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.81050633 |
11 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.66681889 |
12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.64353271 |
13 | MAF_26560356_Chip-Seq_TH1_Human | 2.55194886 |
14 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.53686014 |
15 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.49849095 |
16 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.49561693 |
17 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.40984842 |
18 | MYB_26560356_Chip-Seq_TH2_Human | 2.38922936 |
19 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.38814118 |
20 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.38760928 |
21 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.36318346 |
22 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.30852983 |
23 | * UTX_26944678_Chip-Seq_JUKART_Human | 2.30097482 |
24 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.28827938 |
25 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.28173887 |
26 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.27499054 |
27 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.24645240 |
28 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.22967171 |
29 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.19319885 |
30 | MYB_26560356_Chip-Seq_TH1_Human | 2.18505916 |
31 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.15492466 |
32 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.12491284 |
33 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 2.08021614 |
34 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.03615880 |
35 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.00361440 |
36 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.98494946 |
37 | SPI1_23127762_ChIP-Seq_K562_Human | 1.98398069 |
38 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.94734578 |
39 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.92560614 |
40 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.92086043 |
41 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.90691417 |
42 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.87574600 |
43 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.87086583 |
44 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.85262565 |
45 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.83545888 |
46 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.80589639 |
47 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.78628719 |
48 | * P68_20966046_ChIP-Seq_HELA_Human | 1.77538499 |
49 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.76393003 |
50 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.74996482 |
51 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.68685317 |
52 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.65448392 |
53 | MAF_26560356_Chip-Seq_TH2_Human | 1.64319458 |
54 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.60834473 |
55 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.58021158 |
56 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.57216797 |
57 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.52225370 |
58 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.51701940 |
59 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50492414 |
60 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.48037719 |
61 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.46611528 |
62 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.46276857 |
63 | GATA1_22025678_ChIP-Seq_K562_Human | 1.46034848 |
64 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.45972094 |
65 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.44927918 |
66 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.44717750 |
67 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.43326748 |
68 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.41353237 |
69 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.40521906 |
70 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.40366706 |
71 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.40345325 |
72 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.40315754 |
73 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.38290171 |
74 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.37855279 |
75 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37606447 |
76 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.37397919 |
77 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.34656544 |
78 | * ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.34589409 |
79 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.33197872 |
80 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.32933759 |
81 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.32567593 |
82 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.30927414 |
83 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.30645626 |
84 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.28583427 |
85 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.27725751 |
86 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.26263536 |
87 | * TP63_22573176_ChIP-Seq_HFKS_Human | 1.26236261 |
88 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24896864 |
89 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.24675473 |
90 | * TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.21621550 |
91 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.20498067 |
92 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.19509325 |
93 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.19035607 |
94 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.17644837 |
95 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.16203763 |
96 | * E2F1_20622854_ChIP-Seq_HELA_Human | 1.16004644 |
97 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.15683116 |
98 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.15384892 |
99 | * PHF8_20622854_ChIP-Seq_HELA_Human | 1.14130949 |
100 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.14065828 |
101 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.10578317 |
102 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.09264516 |
103 | SA1_27219007_Chip-Seq_Bcells_Human | 1.08329359 |
104 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.08106496 |
105 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.08082860 |
106 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.08069058 |
107 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.08055714 |
108 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.07632838 |
109 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.07095190 |
110 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.07039413 |
111 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.05729371 |
112 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.05710267 |
113 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.04589920 |
114 | * DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.04082176 |
115 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.02359932 |
116 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.02224741 |
117 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.01607503 |
118 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.01586798 |
119 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.00609583 |
120 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.98330105 |
121 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.97965067 |
122 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.96722997 |
123 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.94823510 |
124 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.93325494 |
125 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.91927636 |
126 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.91880162 |
127 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.90208833 |
128 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.89587622 |
129 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.89194529 |
130 | GATA1_19941826_ChIP-Seq_K562_Human | 0.88482750 |
131 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.88181136 |
132 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.87732430 |
133 | * ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.87077808 |
134 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.86560233 |
135 | * CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.84390945 |
136 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.83986465 |
137 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83624856 |
138 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.83232589 |
139 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.82554968 |
140 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.81994309 |
141 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.81908699 |
142 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.81908699 |
143 | GATA2_19941826_ChIP-Seq_K562_Human | 0.81287816 |
144 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.81232457 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005451_abnormal_body_composition | 3.14300274 |
2 | MP0001835_abnormal_antigen_presentation | 3.05397166 |
3 | MP0009278_abnormal_bone_marrow | 2.82184213 |
4 | MP0000685_abnormal_immune_system | 2.70645824 |
5 | MP0001800_abnormal_humoral_immune | 2.69886771 |
6 | MP0001790_abnormal_immune_system | 2.65918870 |
7 | MP0005387_immune_system_phenotype | 2.65918870 |
8 | MP0004145_abnormal_muscle_electrophysio | 2.59862143 |
9 | MP0003300_gastrointestinal_ulcer | 2.59011665 |
10 | MP0002396_abnormal_hematopoietic_system | 2.57643157 |
11 | MP0004808_abnormal_hematopoietic_stem | 2.52629770 |
12 | MP0005409_darkened_coat_color | 2.43188867 |
13 | MP0003763_abnormal_thymus_physiology | 2.43018302 |
14 | MP0005671_abnormal_response_to | 2.40362225 |
15 | MP0002452_abnormal_antigen_presenting | 2.32331583 |
16 | MP0003303_peritoneal_inflammation | 2.31399525 |
17 | MP0002398_abnormal_bone_marrow | 2.16319446 |
18 | MP0003436_decreased_susceptibility_to | 2.13581266 |
19 | MP0000678_abnormal_parathyroid_gland | 2.12155007 |
20 | MP0002420_abnormal_adaptive_immunity | 2.12105117 |
21 | MP0005000_abnormal_immune_tolerance | 2.11023215 |
22 | MP0001819_abnormal_immune_cell | 2.10195503 |
23 | MP0001873_stomach_inflammation | 2.09804742 |
24 | MP0002723_abnormal_immune_serum | 2.08078758 |
25 | MP0002166_altered_tumor_susceptibility | 1.99743561 |
26 | MP0008961_abnormal_basal_metabolism | 1.89679358 |
27 | MP0000716_abnormal_immune_system | 1.83927786 |
28 | MP0010352_gastrointestinal_tract_polyps | 1.83563211 |
29 | MP0004036_abnormal_muscle_relaxation | 1.83021505 |
30 | MP0004510_myositis | 1.81658371 |
31 | MP0005076_abnormal_cell_differentiation | 1.81249200 |
32 | MP0001545_abnormal_hematopoietic_system | 1.78818523 |
33 | MP0005397_hematopoietic_system_phenotyp | 1.78818523 |
34 | MP0010155_abnormal_intestine_physiology | 1.76546119 |
35 | MP0000703_abnormal_thymus_morphology | 1.73826732 |
36 | MP0004947_skin_inflammation | 1.72061726 |
37 | MP0005025_abnormal_response_to | 1.71121483 |
38 | MP0005083_abnormal_biliary_tract | 1.70230595 |
39 | MP0000689_abnormal_spleen_morphology | 1.69832272 |
40 | MP0003866_abnormal_defecation | 1.68833311 |
41 | MP0003705_abnormal_hypodermis_morpholog | 1.68737256 |
42 | MP0009785_altered_susceptibility_to | 1.67043086 |
43 | MP0002722_abnormal_immune_system | 1.66963504 |
44 | MP0002405_respiratory_system_inflammati | 1.66184387 |
45 | MP0002419_abnormal_innate_immunity | 1.64488277 |
46 | MP0005058_abnormal_lysosome_morphology | 1.60569857 |
47 | MP0003183_abnormal_peptide_metabolism | 1.56574358 |
48 | MP0002429_abnormal_blood_cell | 1.54606617 |
49 | MP0000465_gastrointestinal_hemorrhage | 1.48877418 |
50 | MP0004858_abnormal_nervous_system | 1.47424019 |
51 | MP0002006_tumorigenesis | 1.47375245 |
52 | MP0002877_abnormal_melanocyte_morpholog | 1.46779632 |
53 | MP0003828_pulmonary_edema | 1.45835604 |
54 | MP0003566_abnormal_cell_adhesion | 1.41294008 |
55 | MP0001853_heart_inflammation | 1.39844642 |
56 | MP0009333_abnormal_splenocyte_physiolog | 1.39436086 |
57 | MP0002148_abnormal_hypersensitivity_rea | 1.38462854 |
58 | MP0000490_abnormal_crypts_of | 1.37252582 |
59 | MP0003656_abnormal_erythrocyte_physiolo | 1.36019999 |
60 | MP0002249_abnormal_larynx_morphology | 1.36018801 |
61 | MP0000759_abnormal_skeletal_muscle | 1.33329489 |
62 | MP0005310_abnormal_salivary_gland | 1.32362791 |
63 | MP0001765_abnormal_ion_homeostasis | 1.30203700 |
64 | MP0005464_abnormal_platelet_physiology | 1.29982890 |
65 | MP0000569_abnormal_digit_pigmentation | 1.28323276 |
66 | MP0000013_abnormal_adipose_tissue | 1.28237722 |
67 | MP0004043_abnormal_pH_regulation | 1.28085603 |
68 | MP0001845_abnormal_inflammatory_respons | 1.25457339 |
69 | MP0006138_congestive_heart_failure | 1.24061630 |
70 | MP0000733_abnormal_muscle_development | 1.21316844 |
71 | MP0000747_muscle_weakness | 1.20932433 |
72 | MP0001849_ear_inflammation | 1.20278014 |
73 | MP0005174_abnormal_tail_pigmentation | 1.19626392 |
74 | MP0002009_preneoplasia | 1.19458548 |
75 | MP0002933_joint_inflammation | 1.18921622 |
76 | MP0004084_abnormal_cardiac_muscle | 1.18849245 |
77 | MP0002138_abnormal_hepatobiliary_system | 1.18394631 |
78 | MP0003879_abnormal_hair_cell | 1.15738948 |
79 | MP0005369_muscle_phenotype | 1.12886490 |
80 | MP0000681_abnormal_thyroid_gland | 1.10787281 |
81 | MP0001664_abnormal_digestion | 1.09737990 |
82 | MP0004381_abnormal_hair_follicle | 1.09699117 |
83 | MP0010368_abnormal_lymphatic_system | 1.09554938 |
84 | MP0004130_abnormal_muscle_cell | 1.09210587 |
85 | MP0006054_spinal_hemorrhage | 1.04004818 |
86 | MP0003646_muscle_fatigue | 1.03835257 |
87 | MP0009840_abnormal_foam_cell | 1.03319612 |
88 | MP0000749_muscle_degeneration | 1.03303013 |
89 | MP0002132_abnormal_respiratory_system | 1.02887018 |
90 | MP0001533_abnormal_skeleton_physiology | 1.02577224 |
91 | MP0010630_abnormal_cardiac_muscle | 1.02009970 |
92 | MP0003045_fibrosis | 1.01860024 |
93 | MP0008004_abnormal_stomach_pH | 1.00072844 |
94 | MP0005381_digestive/alimentary_phenotyp | 0.99434854 |
95 | MP0004233_abnormal_muscle_weight | 0.98105857 |
96 | MP0000470_abnormal_stomach_morphology | 0.97968442 |
97 | MP0003279_aneurysm | 0.96128702 |
98 | MP0000767_abnormal_smooth_muscle | 0.94310012 |
99 | MP0008260_abnormal_autophagy | 0.92245441 |
100 | MP0010307_abnormal_tumor_latency | 0.91994852 |
101 | MP0005670_abnormal_white_adipose | 0.91151328 |
102 | MP0001879_abnormal_lymphatic_vessel | 0.91086356 |
103 | MP0000249_abnormal_blood_vessel | 0.90721892 |
104 | MP0003693_abnormal_embryo_hatching | 0.90700728 |
105 | MP0002332_abnormal_exercise_endurance | 0.89428794 |
106 | MP0005330_cardiomyopathy | 0.89404751 |
107 | MP0006082_CNS_inflammation | 0.89039013 |
108 | MP0004147_increased_porphyrin_level | 0.87716914 |
109 | MP0001851_eye_inflammation | 0.87262218 |
110 | MP0002019_abnormal_tumor_incidence | 0.86389882 |
111 | MP0002108_abnormal_muscle_morphology | 0.85963765 |
112 | MP0002928_abnormal_bile_duct | 0.85744251 |
113 | MP0004264_abnormal_extraembryonic_tissu | 0.85447217 |
114 | MP0003448_altered_tumor_morphology | 0.84166036 |
115 | MP0002106_abnormal_muscle_physiology | 0.83825691 |
116 | MP0003943_abnormal_hepatobiliary_system | 0.82154807 |
117 | MP0002971_abnormal_brown_adipose | 0.81718391 |
118 | MP0004087_abnormal_muscle_fiber | 0.81549846 |
119 | MP0002998_abnormal_bone_remodeling | 0.81529077 |
120 | MP0002925_abnormal_cardiovascular_devel | 0.80640686 |
121 | MP0003091_abnormal_cell_migration | 0.80421922 |
122 | MP0002693_abnormal_pancreas_physiology | 0.76718251 |
123 | MP0008007_abnormal_cellular_replicative | 0.76576203 |
124 | MP0000003_abnormal_adipose_tissue | 0.75923946 |
125 | MP0003077_abnormal_cell_cycle | 0.75818457 |
126 | MP0004185_abnormal_adipocyte_glucose | 0.74938979 |
127 | MP0003172_abnormal_lysosome_physiology | 0.73975198 |
128 | MP0005375_adipose_tissue_phenotype | 0.73063609 |
129 | MP0008995_early_reproductive_senescence | 0.71052412 |
130 | MP0000266_abnormal_heart_morphology | 0.70621580 |
131 | MP0000858_altered_metastatic_potential | 0.67925218 |
132 | MP0003984_embryonic_growth_retardation | 0.67729654 |
133 | MP0000750_abnormal_muscle_regeneration | 0.67257399 |
134 | MP0003795_abnormal_bone_structure | 0.66576864 |
135 | MP0005023_abnormal_wound_healing | 0.66295614 |
136 | MP0002088_abnormal_embryonic_growth/wei | 0.65650311 |
137 | MP0003724_increased_susceptibility_to | 0.64841906 |
138 | MP0005666_abnormal_adipose_tissue | 0.62219492 |
139 | MP0000751_myopathy | 0.61726272 |
140 | MP0001663_abnormal_digestive_system | 0.61666098 |
141 | MP0000313_abnormal_cell_death | 0.60794445 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Exercise-induced myalgia (HP:0003738) | 4.75173244 |
2 | Abnormality of the fingertips (HP:0001211) | 4.50163458 |
3 | Muscle fiber inclusion bodies (HP:0100299) | 4.14948943 |
4 | Agammaglobulinemia (HP:0004432) | 4.11401322 |
5 | Nemaline bodies (HP:0003798) | 3.97753944 |
6 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 3.95519789 |
7 | Type 1 muscle fiber predominance (HP:0003803) | 3.89552909 |
8 | Cellulitis (HP:0100658) | 3.87788737 |
9 | Obstructive sleep apnea (HP:0002870) | 3.82720035 |
10 | Myopathic facies (HP:0002058) | 3.78156236 |
11 | Recurrent viral infections (HP:0004429) | 3.51088702 |
12 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 3.45688262 |
13 | Recurrent fungal infections (HP:0002841) | 3.33176055 |
14 | Recurrent bronchitis (HP:0002837) | 3.30758068 |
15 | Chronic otitis media (HP:0000389) | 3.26020793 |
16 | Panhypogammaglobulinemia (HP:0003139) | 3.24516269 |
17 | Inflammation of the large intestine (HP:0002037) | 3.16239147 |
18 | Gastrointestinal inflammation (HP:0004386) | 3.12627828 |
19 | Colitis (HP:0002583) | 3.09662232 |
20 | Hematochezia (HP:0002573) | 3.06218699 |
21 | Increased connective tissue (HP:0009025) | 3.04588535 |
22 | Spontaneous hematomas (HP:0007420) | 3.02025207 |
23 | Eczematoid dermatitis (HP:0000976) | 2.96732151 |
24 | Distal lower limb amyotrophy (HP:0008944) | 2.93612780 |
25 | Verrucae (HP:0200043) | 2.93302560 |
26 | Papilloma (HP:0012740) | 2.93302560 |
27 | Muscle fiber splitting (HP:0003555) | 2.89811609 |
28 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.87470126 |
29 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.87468015 |
30 | IgM deficiency (HP:0002850) | 2.86293749 |
31 | Broad face (HP:0000283) | 2.85051756 |
32 | Thyroiditis (HP:0100646) | 2.81487462 |
33 | Abnormality of B cell number (HP:0010975) | 2.80486569 |
34 | B lymphocytopenia (HP:0010976) | 2.80486569 |
35 | Recurrent abscess formation (HP:0002722) | 2.79280635 |
36 | Round ear (HP:0100830) | 2.76402264 |
37 | Meningitis (HP:0001287) | 2.75042750 |
38 | Asymmetric septal hypertrophy (HP:0001670) | 2.73727498 |
39 | Abnormality of the nasal mucosa (HP:0000433) | 2.66426321 |
40 | Increased variability in muscle fiber diameter (HP:0003557) | 2.64195767 |
41 | Easy fatigability (HP:0003388) | 2.61724081 |
42 | Hyperkalemia (HP:0002153) | 2.59340243 |
43 | Gastrointestinal stroma tumor (HP:0100723) | 2.58623773 |
44 | Hyperacusis (HP:0010780) | 2.58219837 |
45 | Myositis (HP:0100614) | 2.57248472 |
46 | Recurrent bacterial skin infections (HP:0005406) | 2.55127296 |
47 | Long eyelashes (HP:0000527) | 2.54947989 |
48 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.54088484 |
49 | Flat acetabular roof (HP:0003180) | 2.54079155 |
50 | T lymphocytopenia (HP:0005403) | 2.50707878 |
51 | Distal lower limb muscle weakness (HP:0009053) | 2.50543154 |
52 | Cerebral aneurysm (HP:0004944) | 2.50488286 |
53 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.50308787 |
54 | Hemorrhage of the eye (HP:0011885) | 2.48395233 |
55 | Osteomyelitis (HP:0002754) | 2.47929547 |
56 | Nasal polyposis (HP:0100582) | 2.41804022 |
57 | Autoimmune thrombocytopenia (HP:0001973) | 2.40708208 |
58 | Polycythemia (HP:0001901) | 2.39844564 |
59 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.39701855 |
60 | Recurrent cutaneous fungal infections (HP:0011370) | 2.39701855 |
61 | Lymphopenia (HP:0001888) | 2.38699984 |
62 | Abnormality of the intervertebral disk (HP:0005108) | 2.38114557 |
63 | Increased density of long bones (HP:0006392) | 2.37288967 |
64 | Chest pain (HP:0100749) | 2.37275124 |
65 | Thin bony cortex (HP:0002753) | 2.36252954 |
66 | Abnormality of T cell number (HP:0011839) | 2.34788913 |
67 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.34043172 |
68 | Pustule (HP:0200039) | 2.33220154 |
69 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.29515307 |
70 | Muscle hypertrophy of the lower extremities (HP:0008968) | 2.27088826 |
71 | Bulbar palsy (HP:0001283) | 2.26877208 |
72 | Abnormality of T cells (HP:0002843) | 2.26361908 |
73 | Mediastinal lymphadenopathy (HP:0100721) | 2.25198192 |
74 | Ileus (HP:0002595) | 2.24199595 |
75 | Hyporeflexia of lower limbs (HP:0002600) | 2.22037495 |
76 | Rectal prolapse (HP:0002035) | 2.21883049 |
77 | Aortic aneurysm (HP:0004942) | 2.20813779 |
78 | Chronic sinusitis (HP:0011109) | 2.18018081 |
79 | Emphysema (HP:0002097) | 2.17320493 |
80 | Vasculitis (HP:0002633) | 2.15723872 |
81 | Epistaxis (HP:0000421) | 2.15074102 |
82 | Decreased circulating renin level (HP:0003351) | 2.14989129 |
83 | Facial diplegia (HP:0001349) | 2.13862720 |
84 | Severe combined immunodeficiency (HP:0004430) | 2.10935534 |
85 | Sepsis (HP:0100806) | 2.09757758 |
86 | Dysmetric saccades (HP:0000641) | 2.09630480 |
87 | Vertebral arch anomaly (HP:0008438) | 2.09495598 |
88 | Macroorchidism (HP:0000053) | 2.08433291 |
89 | Stridor (HP:0010307) | 2.08376358 |
90 | Malnutrition (HP:0004395) | 2.08012117 |
91 | Hyperthyroidism (HP:0000836) | 2.07508380 |
92 | Periodontitis (HP:0000704) | 2.06053966 |
93 | Spinal cord lesions (HP:0100561) | 2.05590499 |
94 | Syringomyelia (HP:0003396) | 2.05590499 |
95 | Genetic anticipation (HP:0003743) | 2.04622498 |
96 | Clumsiness (HP:0002312) | 2.03715649 |
97 | Limited elbow extension (HP:0001377) | 2.02760596 |
98 | Lip pit (HP:0100267) | 2.02194501 |
99 | Difficulty running (HP:0009046) | 2.01635303 |
100 | Thrombocytosis (HP:0001894) | 1.99961569 |
101 | Atelectasis (HP:0100750) | 1.98213702 |
102 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.97023787 |
103 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.95578821 |
104 | Eosinophilia (HP:0001880) | 1.95491201 |
105 | Restrictive lung disease (HP:0002091) | 1.95023618 |
106 | Gingivitis (HP:0000230) | 1.94028939 |
107 | Ulnar deviation of the wrist (HP:0003049) | 1.93569807 |
108 | Petechiae (HP:0000967) | 1.93045251 |
109 | Abnormality of T cell physiology (HP:0011840) | 1.93020234 |
110 | Volvulus (HP:0002580) | 1.92148489 |
111 | Recurrent skin infections (HP:0001581) | 1.91342234 |
112 | Calf muscle hypertrophy (HP:0008981) | 1.91300107 |
113 | Chronic diarrhea (HP:0002028) | 1.90524112 |
114 | Prolonged bleeding time (HP:0003010) | 1.90261709 |
115 | Recurrent sinusitis (HP:0011108) | 1.89898525 |
116 | EMG: myopathic abnormalities (HP:0003458) | 1.88848057 |
117 | Arterial thrombosis (HP:0004420) | 1.87263185 |
118 | Acute myeloid leukemia (HP:0004808) | 1.86541384 |
119 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.85888013 |
120 | Subaortic stenosis (HP:0001682) | 1.85888013 |
121 | Muscle stiffness (HP:0003552) | 1.85476037 |
122 | Ventricular fibrillation (HP:0001663) | 1.85239551 |
123 | Orchitis (HP:0100796) | 1.85123348 |
124 | Urethral obstruction (HP:0000796) | 1.85036020 |
125 | Frequent falls (HP:0002359) | 1.84578016 |
126 | IgA deficiency (HP:0002720) | 1.84392388 |
127 | Spondylolisthesis (HP:0003302) | 1.83248514 |
128 | Reticulocytosis (HP:0001923) | 1.82757791 |
129 | Combined immunodeficiency (HP:0005387) | 1.82290714 |
130 | Neck muscle weakness (HP:0000467) | 1.82205249 |
131 | Interstitial pulmonary disease (HP:0006530) | 1.79920230 |
132 | Prominent nose (HP:0000448) | 1.79831004 |
133 | EMG: neuropathic changes (HP:0003445) | 1.79613978 |
134 | Abnormality of eosinophils (HP:0001879) | 1.79295231 |
135 | Leukocytosis (HP:0001974) | 1.78922002 |
136 | Bronchitis (HP:0012387) | 1.78807465 |
137 | Seborrheic dermatitis (HP:0001051) | 1.78240981 |
138 | Increased cerebral lipofuscin (HP:0011813) | 1.77753147 |
139 | Hemoptysis (HP:0002105) | 1.77439531 |
140 | Rhabdomyolysis (HP:0003201) | 1.77160498 |
141 | Increased serum ferritin (HP:0003281) | 1.76764169 |
142 | Persistence of primary teeth (HP:0006335) | 1.76229835 |
143 | Pulmonary infiltrates (HP:0002113) | 1.75574164 |
144 | Cheilitis (HP:0100825) | 1.72421623 |
145 | Abnormality of the columella (HP:0009929) | 1.72346108 |
146 | Optic neuritis (HP:0100653) | 1.70896656 |
147 | Retrobulbar optic neuritis (HP:0100654) | 1.70896656 |
148 | Increased IgE level (HP:0003212) | 1.70513976 |
149 | Hypoplasia of the thymus (HP:0000778) | 1.70263454 |
150 | Recurrent pneumonia (HP:0006532) | 1.69393746 |
151 | Skin ulcer (HP:0200042) | 1.69056257 |
152 | Onion bulb formation (HP:0003383) | 1.68642765 |
153 | Disproportionate tall stature (HP:0001519) | 1.68078907 |
154 | Distal arthrogryposis (HP:0005684) | 1.67925240 |
155 | Thoracic kyphosis (HP:0002942) | 1.67013209 |
156 | Aneurysm (HP:0002617) | 1.66975991 |
157 | Narrow palate (HP:0000189) | 1.66641052 |
158 | Fatigue (HP:0012378) | 1.66301789 |
159 | Difficulty climbing stairs (HP:0003551) | 1.66173408 |
160 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.65430891 |
161 | Hyperactive renin-angiotensin system (HP:0000841) | 1.65252009 |
162 | Lymphoma (HP:0002665) | 1.65142219 |
163 | Hypertensive crisis (HP:0100735) | 1.65084038 |
164 | Dislocated radial head (HP:0003083) | 1.64542052 |
165 | Generalized muscle weakness (HP:0003324) | 1.64538049 |
166 | IgG deficiency (HP:0004315) | 1.64253563 |
167 | Abnormality of iron homeostasis (HP:0011031) | 1.63424383 |
168 | Dysostosis multiplex (HP:0000943) | 1.63235140 |
169 | Germ cell neoplasia (HP:0100728) | 1.62969050 |
170 | Abnormality of the thoracic spine (HP:0100711) | 1.61828521 |
171 | Gastrointestinal dysmotility (HP:0002579) | 1.60960315 |
172 | Bowel incontinence (HP:0002607) | 1.59859824 |
173 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.57514143 |
174 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.57514143 |
175 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.57514143 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP4K1 | 4.03654113 |
2 | MAP3K10 | 3.85300616 |
3 | CDK12 | 3.27394420 |
4 | ERN1 | 2.94406150 |
5 | EEF2K | 2.86834195 |
6 | TRIB3 | 2.38189607 |
7 | FGFR4 | 2.24818706 |
8 | TGFBR2 | 2.22838312 |
9 | JAK3 | 2.15847815 |
10 | PRPF4B | 2.07008608 |
11 | TNK2 | 2.02427653 |
12 | TTN | 1.94858168 |
13 | FGFR3 | 1.90002576 |
14 | TYK2 | 1.87223677 |
15 | BTK | 1.78584770 |
16 | ZAP70 | 1.76150502 |
17 | SIK2 | 1.72449998 |
18 | TXK | 1.67690441 |
19 | STK10 | 1.66249418 |
20 | PKN2 | 1.65737214 |
21 | ITK | 1.61898567 |
22 | SIK3 | 1.60686804 |
23 | BRD4 | 1.60540157 |
24 | CAMK1D | 1.59056060 |
25 | KIT | 1.57877313 |
26 | JAK1 | 1.48766704 |
27 | CDC42BPA | 1.47355678 |
28 | CAMK1G | 1.45044279 |
29 | SYK | 1.42689706 |
30 | SIK1 | 1.41643184 |
31 | MAPK15 | 1.38190025 |
32 | IRAK4 | 1.35317336 |
33 | BLK | 1.35255967 |
34 | MST1R | 1.35111763 |
35 | SMG1 | 1.33858098 |
36 | TBK1 | 1.33468749 |
37 | CSF1R | 1.27597284 |
38 | HCK | 1.23107953 |
39 | IRAK3 | 1.20418439 |
40 | PTK6 | 1.19954376 |
41 | MAP3K14 | 1.18874211 |
42 | IKBKE | 1.15808500 |
43 | MAP3K1 | 1.15045534 |
44 | TEC | 1.14055048 |
45 | PHKG2 | 1.13392464 |
46 | PHKG1 | 1.13392464 |
47 | MAP2K3 | 1.12901316 |
48 | GRK6 | 1.12581806 |
49 | FLT3 | 1.11753563 |
50 | CHUK | 1.09305471 |
51 | FGFR2 | 1.08346287 |
52 | RIPK1 | 1.07732384 |
53 | MAP3K3 | 1.07293218 |
54 | MAP2K6 | 1.07039449 |
55 | TGFBR1 | 1.03697449 |
56 | DMPK | 1.03658996 |
57 | FES | 1.03536313 |
58 | LRRK2 | 1.00377325 |
59 | TIE1 | 1.00036901 |
60 | EPHB1 | 0.99258984 |
61 | PDPK1 | 0.99250317 |
62 | TAOK3 | 0.97365201 |
63 | EPHA2 | 0.96646245 |
64 | MAP3K7 | 0.95582065 |
65 | HIPK2 | 0.94566838 |
66 | IKBKB | 0.94348212 |
67 | PDGFRA | 0.91717910 |
68 | NLK | 0.88626546 |
69 | MAP2K2 | 0.88554971 |
70 | PRKAA2 | 0.88547184 |
71 | MAP3K11 | 0.87825870 |
72 | RPS6KL1 | 0.86946241 |
73 | RPS6KC1 | 0.86946241 |
74 | CDK9 | 0.86779277 |
75 | RPS6KA4 | 0.85944624 |
76 | MAP3K6 | 0.85867961 |
77 | ICK | 0.85808789 |
78 | BMX | 0.85782739 |
79 | LCK | 0.84396169 |
80 | MTOR | 0.81162884 |
81 | PDK1 | 0.78806732 |
82 | STK4 | 0.77885682 |
83 | NEK2 | 0.77564323 |
84 | PIM1 | 0.76110956 |
85 | MARK3 | 0.76023255 |
86 | PRKD3 | 0.75967307 |
87 | PDGFRB | 0.74863595 |
88 | LMTK2 | 0.74620590 |
89 | LYN | 0.73366484 |
90 | CDK4 | 0.72080726 |
91 | CSK | 0.71464382 |
92 | JAK2 | 0.69161101 |
93 | RIPK4 | 0.63185401 |
94 | CLK1 | 0.63019170 |
95 | CDK6 | 0.62309957 |
96 | PTK2B | 0.61096441 |
97 | STK3 | 0.58894259 |
98 | MAPKAPK3 | 0.57507848 |
99 | NME1 | 0.56145498 |
100 | WNK1 | 0.55379293 |
101 | MARK2 | 0.53065946 |
102 | MAP2K1 | 0.51970217 |
103 | KSR2 | 0.51648593 |
104 | EPHA3 | 0.51019889 |
105 | PRKG2 | 0.50643517 |
106 | PRKAA1 | 0.50364462 |
107 | STK38 | 0.49735607 |
108 | PIK3CA | 0.49673045 |
109 | MAP3K2 | 0.49630014 |
110 | PRKD2 | 0.48925193 |
111 | DYRK1B | 0.48567447 |
112 | IRAK1 | 0.47860151 |
113 | PASK | 0.47732656 |
114 | RPS6KB2 | 0.47711891 |
115 | MAPK11 | 0.46396339 |
116 | ATR | 0.45369128 |
117 | MUSK | 0.44793640 |
118 | RET | 0.44708305 |
119 | STK24 | 0.44380504 |
120 | MAPK12 | 0.43306090 |
121 | PRKD1 | 0.42689523 |
122 | SGK3 | 0.42553140 |
123 | PIK3CG | 0.42370808 |
124 | PRKCH | 0.42222031 |
125 | SCYL2 | 0.42111294 |
126 | MAPKAPK2 | 0.40907037 |
127 | ALK | 0.40504801 |
128 | MAP3K13 | 0.40069151 |
129 | TRPM7 | 0.37264127 |
130 | TAOK1 | 0.34596880 |
131 | MAPK7 | 0.33720824 |
132 | RPS6KA2 | 0.33483404 |
133 | ABL1 | 0.32105363 |
134 | RPS6KA6 | 0.30974347 |
135 | OBSCN | 0.30838392 |
136 | INSRR | 0.29864077 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.85205541 |
2 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.59588848 |
3 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.35379705 |
4 | Leishmaniasis_Homo sapiens_hsa05140 | 2.09196317 |
5 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.01021312 |
6 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.76384765 |
7 | Measles_Homo sapiens_hsa05162 | 1.72900105 |
8 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.61422811 |
9 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.60660345 |
10 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.59374686 |
11 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.58699150 |
12 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.58011635 |
13 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.57801635 |
14 | Viral myocarditis_Homo sapiens_hsa05416 | 1.56798399 |
15 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.56243481 |
16 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.52913085 |
17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.51619742 |
18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.48543917 |
19 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.45504454 |
20 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.41059980 |
21 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.40226899 |
22 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.35480009 |
23 | Influenza A_Homo sapiens_hsa05164 | 1.35300127 |
24 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.31010737 |
25 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.30639742 |
26 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.29156080 |
27 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.28781075 |
28 | Hepatitis B_Homo sapiens_hsa05161 | 1.28684082 |
29 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.26807774 |
30 | Apoptosis_Homo sapiens_hsa04210 | 1.26543564 |
31 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.26178413 |
32 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.25018800 |
33 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.24755744 |
34 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.22214461 |
35 | Shigellosis_Homo sapiens_hsa05131 | 1.18130543 |
36 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.16510590 |
37 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.14840915 |
38 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.14645716 |
39 | Lysine degradation_Homo sapiens_hsa00310 | 1.14582165 |
40 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.14519759 |
41 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.14105394 |
42 | * Insulin resistance_Homo sapiens_hsa04931 | 1.12782137 |
43 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.12562048 |
44 | Tuberculosis_Homo sapiens_hsa05152 | 1.11721987 |
45 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.11553256 |
46 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.11058312 |
47 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.10711883 |
48 | Platelet activation_Homo sapiens_hsa04611 | 1.09014630 |
49 | HTLV-I infection_Homo sapiens_hsa05166 | 1.08262336 |
50 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.07140128 |
51 | Legionellosis_Homo sapiens_hsa05134 | 1.05383493 |
52 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.01739549 |
53 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.01398411 |
54 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.99987098 |
55 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.99183370 |
56 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.98930265 |
57 | Colorectal cancer_Homo sapiens_hsa05210 | 0.96346708 |
58 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.96005806 |
59 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.94579591 |
60 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.93980790 |
61 | Pertussis_Homo sapiens_hsa05133 | 0.93922551 |
62 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.92152940 |
63 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.91836503 |
64 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.90812826 |
65 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.89547014 |
66 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.89437769 |
67 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.88051882 |
68 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.87316985 |
69 | Adherens junction_Homo sapiens_hsa04520 | 0.84839594 |
70 | Salmonella infection_Homo sapiens_hsa05132 | 0.81113700 |
71 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.80985278 |
72 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.80590980 |
73 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.79038798 |
74 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.77353485 |
75 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.77284582 |
76 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.77202781 |
77 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.76909518 |
78 | Hepatitis C_Homo sapiens_hsa05160 | 0.76834693 |
79 | Malaria_Homo sapiens_hsa05144 | 0.76408943 |
80 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.76408298 |
81 | Allograft rejection_Homo sapiens_hsa05330 | 0.76386186 |
82 | ABC transporters_Homo sapiens_hsa02010 | 0.75976039 |
83 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.74120165 |
84 | Bladder cancer_Homo sapiens_hsa05219 | 0.73817956 |
85 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.72914624 |
86 | Endometrial cancer_Homo sapiens_hsa05213 | 0.71647323 |
87 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.70990496 |
88 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.70644247 |
89 | Focal adhesion_Homo sapiens_hsa04510 | 0.70215863 |
90 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.70215779 |
91 | Other glycan degradation_Homo sapiens_hsa00511 | 0.69862116 |
92 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.69331768 |
93 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.69043538 |
94 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.68868809 |
95 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.67689483 |
96 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.66836383 |
97 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.66587844 |
98 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.66441420 |
99 | Thyroid cancer_Homo sapiens_hsa05216 | 0.65764904 |
100 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.65711633 |
101 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.64402941 |
102 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.64104832 |
103 | Base excision repair_Homo sapiens_hsa03410 | 0.63708144 |
104 | Prostate cancer_Homo sapiens_hsa05215 | 0.63421375 |
105 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.63240495 |
106 | Pathways in cancer_Homo sapiens_hsa05200 | 0.61161371 |
107 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.61047371 |
108 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.60667614 |
109 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.60234837 |
110 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.59783199 |
111 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.59375897 |
112 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.58907497 |
113 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.58567830 |
114 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.56124979 |
115 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.55595162 |
116 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.54757420 |
117 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.54726936 |
118 | Glioma_Homo sapiens_hsa05214 | 0.54722475 |
119 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.54378171 |
120 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.54291292 |
121 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.53872780 |
122 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.53848949 |
123 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.53833673 |
124 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.53702155 |
125 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.53496430 |
126 | Asthma_Homo sapiens_hsa05310 | 0.53300879 |
127 | Circadian rhythm_Homo sapiens_hsa04710 | 0.52820169 |
128 | Amoebiasis_Homo sapiens_hsa05146 | 0.51363657 |
129 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.49286414 |
130 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.49208816 |
131 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.48842177 |
132 | Cell cycle_Homo sapiens_hsa04110 | 0.48488112 |
133 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.46098311 |
134 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.45740282 |