MMS19

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of glycogen biosynthetic process (GO:0045719)4.97341107
2nuclear pore complex assembly (GO:0051292)4.79070211
3Golgi transport vesicle coating (GO:0048200)4.56559343
4COPI coating of Golgi vesicle (GO:0048205)4.56559343
5nuclear pore organization (GO:0006999)4.40186115
6peptidyl-arginine omega-N-methylation (GO:0035247)4.36309156
7mitotic chromosome condensation (GO:0007076)4.30045159
8proline biosynthetic process (GO:0006561)4.29140173
9pore complex assembly (GO:0046931)4.21846104
10negative regulation of glycogen metabolic process (GO:0070874)4.11469662
11heterochromatin organization (GO:0070828)4.06785683
12G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071994.03393389
13negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.02307426
14regulation of NFAT protein import into nucleus (GO:0051532)3.92328927
15protein complex localization (GO:0031503)3.92118266
16L-serine metabolic process (GO:0006563)3.88923545
17gonadal mesoderm development (GO:0007506)3.81707429
18histone arginine methylation (GO:0034969)3.78772005
19protein localization to kinetochore (GO:0034501)3.77548132
20formation of translation preinitiation complex (GO:0001731)3.75171773
21DNA topological change (GO:0006265)3.72766108
22nucleosome disassembly (GO:0006337)3.65342905
23protein-DNA complex disassembly (GO:0032986)3.65342905
24dosage compensation (GO:0007549)3.57262342
25peptidyl-arginine N-methylation (GO:0035246)3.55815675
26peptidyl-arginine methylation (GO:0018216)3.55815675
27DNA unwinding involved in DNA replication (GO:0006268)3.53428232
28establishment of integrated proviral latency (GO:0075713)3.53354796
29negative regulation of mRNA processing (GO:0050686)3.49661716
30negative regulation of RNA splicing (GO:0033119)3.46660225
31positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003603.45700145
32positive regulation of cell cycle checkpoint (GO:1901978)3.44418550
33cellular protein complex localization (GO:0034629)3.42606045
34DNA replication initiation (GO:0006270)3.41795438
35negative regulation of histone methylation (GO:0031061)3.38509651
36retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.30520881
37pentose-phosphate shunt (GO:0006098)3.28687514
38regulation of energy homeostasis (GO:2000505)3.28424441
39mitotic sister chromatid cohesion (GO:0007064)3.26657458
40folic acid-containing compound biosynthetic process (GO:0009396)3.24663272
41spliceosomal tri-snRNP complex assembly (GO:0000244)3.24610808
42planar cell polarity pathway involved in neural tube closure (GO:0090179)3.24118501
43mitotic nuclear envelope disassembly (GO:0007077)3.21657893
44protein retention in ER lumen (GO:0006621)3.21015953
45DNA strand elongation involved in DNA replication (GO:0006271)3.20995435
46NADPH regeneration (GO:0006740)3.18690189
47histone H3-K36 demethylation (GO:0070544)3.17960893
48maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.16912371
49regulation of mammary gland epithelial cell proliferation (GO:0033599)3.16193332
50telomere maintenance via semi-conservative replication (GO:0032201)3.12655222
51mitotic sister chromatid segregation (GO:0000070)3.12120688
52positive regulation of T cell cytokine production (GO:0002726)3.10928122
53regulation of RNA export from nucleus (GO:0046831)3.10479385
54Notch signaling involved in heart development (GO:0061314)3.09295949
55histone H3-K4 methylation (GO:0051568)3.08755876
56DNA geometric change (GO:0032392)3.08648592
57DNA duplex unwinding (GO:0032508)3.08061247
58negative regulation of cell cycle arrest (GO:0071157)3.07428659
59DNA strand elongation (GO:0022616)3.06693692
60regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.05696830
61adherens junction assembly (GO:0034333)3.04698824
62snRNA metabolic process (GO:0016073)3.02944250
63DNA conformation change (GO:0071103)3.02047676
64IMP biosynthetic process (GO:0006188)2.99525237
65regulation of posttranscriptional gene silencing (GO:0060147)2.97577004
66regulation of gene silencing by miRNA (GO:0060964)2.97577004
67regulation of gene silencing by RNA (GO:0060966)2.97577004
68sister chromatid segregation (GO:0000819)2.97098087
69regulation of chromatin binding (GO:0035561)2.97039241
70regulation of nuclear cell cycle DNA replication (GO:0033262)2.95121227
71negative regulation of mRNA metabolic process (GO:1903312)2.94183588
72telomere maintenance via recombination (GO:0000722)2.93390591
73paraxial mesoderm development (GO:0048339)2.92505933
74IMP metabolic process (GO:0046040)2.91919468
75cell-substrate adherens junction assembly (GO:0007045)2.91836804
76focal adhesion assembly (GO:0048041)2.91836804
77protein localization to chromosome, centromeric region (GO:0071459)2.91525506
78venous blood vessel morphogenesis (GO:0048845)2.91469806
79DNA replication checkpoint (GO:0000076)2.90064822
80cellular response to interleukin-4 (GO:0071353)2.89384289
81intra-S DNA damage checkpoint (GO:0031573)2.88395385
82mitotic recombination (GO:0006312)2.86596160
83membrane disassembly (GO:0030397)2.85355892
84nuclear envelope disassembly (GO:0051081)2.85355892
85snRNA processing (GO:0016180)2.84977836
86mitochondrial DNA metabolic process (GO:0032042)2.84450051
87histone H2A monoubiquitination (GO:0035518)2.84156135
88nuclear envelope organization (GO:0006998)2.83830002
89proline metabolic process (GO:0006560)2.83433059
90determination of adult lifespan (GO:0008340)2.82872239
91establishment of viral latency (GO:0019043)2.82570623
92mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.81443797
93peptidyl-lysine dimethylation (GO:0018027)2.80525056
94regulation of telomere maintenance via telomerase (GO:0032210)2.80349079
95tRNA aminoacylation for protein translation (GO:0006418)2.79024670
96regulation of histone H3-K9 methylation (GO:0051570)2.76988123
97telomere maintenance via telomere lengthening (GO:0010833)2.75141164
98histone H3-K9 demethylation (GO:0033169)2.73928249
99response to muramyl dipeptide (GO:0032495)2.73435619
100regulation of nucleobase-containing compound transport (GO:0032239)2.72658276
101convergent extension (GO:0060026)2.72469621
102regulation of DNA damage checkpoint (GO:2000001)2.70087413
103histone H4-K5 acetylation (GO:0043981)2.69456553
104histone H4-K8 acetylation (GO:0043982)2.69456553
105telomere organization (GO:0032200)2.69112346
106glycolytic process (GO:0006096)2.67605809
107cellular hyperosmotic response (GO:0071474)2.67557004
108nucleotide-excision repair, DNA gap filling (GO:0006297)2.66807255
109chromosome condensation (GO:0030261)2.66797459
110regulation of translational fidelity (GO:0006450)2.65767477
111tRNA aminoacylation (GO:0043039)2.64220313
112amino acid activation (GO:0043038)2.64220313
113mRNA stabilization (GO:0048255)2.63289540
114RNA stabilization (GO:0043489)2.63289540
115ribosomal large subunit biogenesis (GO:0042273)2.62896407
116semaphorin-plexin signaling pathway (GO:0071526)2.62646164
117glucose catabolic process (GO:0006007)2.61214725
118mRNA splice site selection (GO:0006376)2.60091591
119cellular response to fluid shear stress (GO:0071498)2.59226952
120positive regulation of SMAD protein import into nucleus (GO:0060391)2.58726688
121histone H3-K4 trimethylation (GO:0080182)2.58221183
122activation of Rac GTPase activity (GO:0032863)2.56884197
123mitotic metaphase plate congression (GO:0007080)2.56774715
124regulation of hippo signaling (GO:0035330)2.56200265
125regulation of histone H3-K27 methylation (GO:0061085)2.55700774
126response to laminar fluid shear stress (GO:0034616)2.55199834
127apoptotic process involved in morphogenesis (GO:0060561)2.54675598
128alternative mRNA splicing, via spliceosome (GO:0000380)2.54639534
129positive regulation of gamma-delta T cell activation (GO:0046645)2.54496619
130chromatin assembly (GO:0031497)2.54324297
131telomere maintenance (GO:0000723)2.54212464
132activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.53736633
133regulation of translation, ncRNA-mediated (GO:0045974)2.53355452
134negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.53355452
135negative regulation of translation, ncRNA-mediated (GO:0040033)2.53355452
136regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.52725972
137positive regulation of nuclease activity (GO:0032075)2.52603434
138mitochondrial fusion (GO:0008053)2.52545837
139kinetochore organization (GO:0051383)2.52277110
140pre-miRNA processing (GO:0031054)2.51800511
141regulation of extracellular matrix disassembly (GO:0010715)2.51201114
142glucocorticoid receptor signaling pathway (GO:0042921)2.51121799
143regulation of cell cycle checkpoint (GO:1901976)2.51007105
144DNA replication-dependent nucleosome organization (GO:0034723)2.50767983
145DNA replication-dependent nucleosome assembly (GO:0006335)2.50767983
146protein localization to endosome (GO:0036010)2.50325540
147regulation of DNA endoreduplication (GO:0032875)2.49595207
148translesion synthesis (GO:0019985)2.49267364
149DNA synthesis involved in DNA repair (GO:0000731)2.48856094
150negative regulation of DNA-dependent DNA replication (GO:2000104)2.48401303
151neural tube development (GO:0021915)2.47710968
152cell proliferation involved in metanephros development (GO:0072203)2.47341819
153regulation of gene silencing (GO:0060968)2.46042845
154base-excision repair (GO:0006284)2.45661378
155regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.44294872
156regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.44009363
157tetrahydrofolate metabolic process (GO:0046653)2.43342372
158histone H2A acetylation (GO:0043968)2.43082497
159deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.42942758
160mismatch repair (GO:0006298)2.42492000
161regulation of helicase activity (GO:0051095)2.42157706
162response to UV-C (GO:0010225)2.42070295
163histone lysine methylation (GO:0034968)2.41814592
164epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.41182021
165poly(A)+ mRNA export from nucleus (GO:0016973)2.40627228
166neuronal stem cell maintenance (GO:0097150)2.38566210
167DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.37633118
168RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.37150767
169mRNA splicing, via spliceosome (GO:0000398)2.37150767
170maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.36769475
171protein export from nucleus (GO:0006611)2.36736792
172NLS-bearing protein import into nucleus (GO:0006607)2.36685789

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.78664516
2E2F4_17652178_ChIP-ChIP_JURKAT_Human3.50492535
3MYC_22102868_ChIP-Seq_BL_Human3.40925014
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.14999630
5HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.14869438
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.13169644
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.83916012
8MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.54360501
9MYC_18555785_ChIP-Seq_MESCs_Mouse2.42611507
10TP63_17297297_ChIP-ChIP_HaCaT_Human2.31456577
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.26076605
12TP63_19390658_ChIP-ChIP_HaCaT_Human2.14708234
13* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.10342655
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.07278270
15ZFX_18555785_ChIP-Seq_MESCs_Mouse2.03361513
16E2F1_21310950_ChIP-Seq_MCF-7_Human2.02933056
17E2F7_22180533_ChIP-Seq_HELA_Human12.1023676
18VDR_21846776_ChIP-Seq_THP-1_Human1.96005275
19POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.94144851
20MYC_19030024_ChIP-ChIP_MESCs_Mouse1.83883220
21CIITA_25753668_ChIP-Seq_RAJI_Human1.79728654
22RBPJ_22232070_ChIP-Seq_NCS_Mouse1.79095676
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.76469246
24NELFA_20434984_ChIP-Seq_ESCs_Mouse1.71943517
25MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.71073741
26FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.70573167
27MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.67699436
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.65730826
29KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.64654639
30KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.64654639
31KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.64654639
32NANOG_18555785_ChIP-Seq_MESCs_Mouse1.62574291
33XRN2_22483619_ChIP-Seq_HELA_Human1.60852834
34ESR1_15608294_ChIP-ChIP_MCF-7_Human1.59019964
35ZFP281_18757296_ChIP-ChIP_E14_Mouse1.57618684
36CLOCK_20551151_ChIP-Seq_293T_Human1.57052950
37MYC_18358816_ChIP-ChIP_MESCs_Mouse1.56204953
38LXR_22292898_ChIP-Seq_THP-1_Human1.53990867
39* RACK7_27058665_Chip-Seq_MCF-7_Human1.48200173
40JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.47411718
41SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.46145365
42EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.45735266
43SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.45622854
44ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.44723372
45TCF7_22412390_ChIP-Seq_EML_Mouse1.43968589
46DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.42385170
47THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.41521228
48SOX2_18555785_ChIP-Seq_MESCs_Mouse1.39981059
49EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.37979671
50ZNF263_19887448_ChIP-Seq_K562_Human1.36598490
51TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.35577516
52AR_21909140_ChIP-Seq_LNCAP_Human1.35521531
53TCF3_18692474_ChIP-Seq_MEFs_Mouse1.35357737
54* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.34614986
55GABP_19822575_ChIP-Seq_HepG2_Human1.32866852
56* MAF_26560356_Chip-Seq_TH1_Human1.32612554
57P300_27058665_Chip-Seq_ZR-75-30cells_Human1.31075001
58CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.30543255
59* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.27856517
60TTF2_22483619_ChIP-Seq_HELA_Human1.26915604
61YY1_21170310_ChIP-Seq_MESCs_Mouse1.26073424
62WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.25370853
63NANOG_21062744_ChIP-ChIP_HESCs_Human1.25272525
64* UTX_26944678_Chip-Seq_JUKART_Human1.24749501
65HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.24708368
66ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.23623167
67CREB1_15753290_ChIP-ChIP_HEK293T_Human1.20790540
68CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.20742134
69SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.20260481
70ETS1_20019798_ChIP-Seq_JURKAT_Human1.19210527
71* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.18670138
72TET1_21451524_ChIP-Seq_MESCs_Mouse1.17623268
73KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.16824129
74ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.16676106
75TCF3_18692474_ChIP-Seq_MESCs_Mouse1.16384177
76NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.15960850
77NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.15706337
78SALL1_21062744_ChIP-ChIP_HESCs_Human1.15331857
79SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.14837842
80P68_20966046_ChIP-Seq_HELA_Human1.14763361
81HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.14607135
82ZFP281_27345836_Chip-Seq_ESCs_Mouse1.14188115
83TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.14169798
84SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13203922
85STAT3_1855785_ChIP-Seq_MESCs_Mouse1.12844763
86PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.12683611
87SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.12170518
88POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.12148052
89RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.11913004
90RARG_19884340_ChIP-ChIP_MEFs_Mouse1.11728429
91KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.10668958
92NOTCH1_21737748_ChIP-Seq_TLL_Human1.10387651
93VDR_24763502_ChIP-Seq_THP-1_Human1.10101431
94KDM2B_26808549_Chip-Seq_K562_Human1.09388965
95STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09191863
96POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.08592125
97MYCN_18555785_ChIP-Seq_MESCs_Mouse1.08409667
98UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.07821845
99* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.07541033
100FOXP3_21729870_ChIP-Seq_TREG_Human1.07405162
101STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.07245558
102ATF3_27146783_Chip-Seq_COLON_Human1.06725039
103KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.06048780
104MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.05690142
105NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.04220856
106ERG_20887958_ChIP-Seq_HPC-7_Mouse1.04025015
107TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse1.03617760
108CTCF_27219007_Chip-Seq_ERYTHROID_Human1.02777276
109KLF4_18555785_ChIP-Seq_MESCs_Mouse1.02351278
110* CHD1_26751641_Chip-Seq_LNCaP_Human1.02204073
111SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.01799154
112* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.00678900
113CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00657939
114CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.00392613
115E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.99057995
116TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98218301
117KDM2B_26808549_Chip-Seq_DND41_Human0.98154360
118KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.96997279
119KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96532601
120MYB_26560356_Chip-Seq_TH1_Human0.95871118
121* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.95177394
122DCP1A_22483619_ChIP-Seq_HELA_Human0.94472410
123SPI1_23547873_ChIP-Seq_NB4_Human0.91559452
124MAF_26560356_Chip-Seq_TH2_Human0.91451735
125MYB_26560356_Chip-Seq_TH2_Human0.91113307
126DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.91061088
127POU5F1_16518401_ChIP-PET_MESCs_Mouse0.90242506
128IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.89907559
129* KDM5A_27292631_Chip-Seq_BREAST_Human0.89019238
130BRD4_27068464_Chip-Seq_AML-cells_Mouse0.87016169
131KDM2B_26808549_Chip-Seq_SUP-B15_Human0.86875689
132NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.85724911
133* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.84083408
134* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.83154624
135ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.82835870
136ELK3_25401928_ChIP-Seq_HUVEC_Human0.82691281
137SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.82664311
138STAT6_21828071_ChIP-Seq_BEAS2B_Human0.81841642
139THAP11_20581084_ChIP-Seq_MESCs_Mouse0.81833228
140* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.81762660
141VDR_23849224_ChIP-Seq_CD4+_Human0.81707098
142* STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.81661880
143SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.81039760
144KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.79704769
145E2F1_18555785_ChIP-Seq_MESCs_Mouse0.78965338
146KDM2B_26808549_Chip-Seq_JURKAT_Human0.78213648

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002653_abnormal_ependyma_morphology3.52542610
2MP0010030_abnormal_orbit_morphology3.18471063
3MP0003111_abnormal_nucleus_morphology3.01975437
4MP0010094_abnormal_chromosome_stability2.85034331
5MP0003077_abnormal_cell_cycle2.56134987
6MP0004233_abnormal_muscle_weight2.50647066
7MP0002396_abnormal_hematopoietic_system2.49829344
8MP0008057_abnormal_DNA_replication2.43958364
9MP0005257_abnormal_intraocular_pressure2.37004539
10MP0005451_abnormal_body_composition2.32241703
11MP0001915_intracranial_hemorrhage2.25819876
12MP0004185_abnormal_adipocyte_glucose2.22764898
13MP0000569_abnormal_digit_pigmentation2.18014093
14MP0008260_abnormal_autophagy2.11560152
15MP0002089_abnormal_postnatal_growth/wei2.07160924
16MP0004272_abnormal_basement_membrane2.07115196
17MP0004957_abnormal_blastocyst_morpholog1.95835093
18MP0008058_abnormal_DNA_repair1.94148557
19MP0005076_abnormal_cell_differentiation1.86539028
20MP0003693_abnormal_embryo_hatching1.83767903
21MP0008438_abnormal_cutaneous_collagen1.78622571
22MP0001661_extended_life_span1.75279378
23MP0004808_abnormal_hematopoietic_stem1.74688039
24MP0000350_abnormal_cell_proliferation1.72411553
25MP0000003_abnormal_adipose_tissue1.71614353
26MP0010234_abnormal_vibrissa_follicle1.70856687
27MP0002877_abnormal_melanocyte_morpholog1.69612862
28MP0000751_myopathy1.69175627
29MP0010352_gastrointestinal_tract_polyps1.67976294
30MP0003763_abnormal_thymus_physiology1.66343173
31MP0008007_abnormal_cellular_replicative1.65487772
32MP0003566_abnormal_cell_adhesion1.64746168
33MP0004197_abnormal_fetal_growth/weight/1.59110520
34MP0003941_abnormal_skin_development1.57531894
35MP0010307_abnormal_tumor_latency1.53553941
36MP0004858_abnormal_nervous_system1.51199587
37MP0002085_abnormal_embryonic_tissue1.49457926
38MP0001730_embryonic_growth_arrest1.48728109
39MP0000371_diluted_coat_color1.47397800
40MP0000703_abnormal_thymus_morphology1.42901409
41MP0004381_abnormal_hair_follicle1.41990859
42MP0005409_darkened_coat_color1.39483274
43MP0005501_abnormal_skin_physiology1.36498909
44MP0005380_embryogenesis_phenotype1.34383130
45MP0001672_abnormal_embryogenesis/_devel1.34383130
46MP0005220_abnormal_exocrine_pancreas1.32448130
47MP0000490_abnormal_crypts_of1.31126619
48MP0001286_abnormal_eye_development1.30167918
49MP0002697_abnormal_eye_size1.29160808
50MP0003115_abnormal_respiratory_system1.25663890
51MP0008789_abnormal_olfactory_epithelium1.25357610
52MP0002088_abnormal_embryonic_growth/wei1.25311911
53MP0008961_abnormal_basal_metabolism1.25285009
54MP0002086_abnormal_extraembryonic_tissu1.25042897
55MP0002092_abnormal_eye_morphology1.23531312
56MP0003984_embryonic_growth_retardation1.23261556
57MP0001299_abnormal_eye_distance/1.22458443
58MP0003121_genomic_imprinting1.22264292
59MP0000015_abnormal_ear_pigmentation1.20890641
60MP0002098_abnormal_vibrissa_morphology1.19533515
61MP0003221_abnormal_cardiomyocyte_apopto1.19421388
62MP0009278_abnormal_bone_marrow1.18181496
63MP0002796_impaired_skin_barrier1.17852430
64MP0002722_abnormal_immune_system1.16483201
65MP0005174_abnormal_tail_pigmentation1.15409619
66MP0005621_abnormal_cell_physiology1.15258076
67MP0002111_abnormal_tail_morphology1.14988461
68MP0002080_prenatal_lethality1.13860390
69MP0001697_abnormal_embryo_size1.11879730
70MP0005499_abnormal_olfactory_system1.10822001
71MP0005394_taste/olfaction_phenotype1.10822001
72MP0005623_abnormal_meninges_morphology1.10556832
73MP0002398_abnormal_bone_marrow1.09600064
74MP0000313_abnormal_cell_death1.09134512
75MP0002084_abnormal_developmental_patter1.08716077
76MP0001800_abnormal_humoral_immune1.06365198
77MP0000013_abnormal_adipose_tissue1.06099643
78MP0000685_abnormal_immune_system1.05365562
79MP0003136_yellow_coat_color1.05218189
80MP0003123_paternal_imprinting1.04664058
81MP0002928_abnormal_bile_duct1.04481787
82MP0000428_abnormal_craniofacial_morphol1.03546964
83MP0005384_cellular_phenotype1.03369223
84MP0000358_abnormal_cell_content/1.02874064
85MP0002254_reproductive_system_inflammat1.02753700
86MP0000858_altered_metastatic_potential1.02607998
87MP0002019_abnormal_tumor_incidence1.02464440
88MP0003119_abnormal_digestive_system1.02050836
89MP0000689_abnormal_spleen_morphology1.01902212
90MP0001293_anophthalmia1.01596254
91MP0000537_abnormal_urethra_morphology1.00911879
92MP0002006_tumorigenesis1.00558132
93MP0008932_abnormal_embryonic_tissue0.99905978
94MP0000566_synostosis0.99892284
95MP0002075_abnormal_coat/hair_pigmentati0.99713349
96MP0003567_abnormal_fetal_cardiomyocyte0.99642670
97MP0003385_abnormal_body_wall0.99305597
98MP0000747_muscle_weakness0.99119822
99MP0010630_abnormal_cardiac_muscle0.98458280
100MP0005375_adipose_tissue_phenotype0.97862667
101MP0002269_muscular_atrophy0.97129184
102MP0000733_abnormal_muscle_development0.96342265
103MP0003786_premature_aging0.94569590
104MP0005023_abnormal_wound_healing0.94401938
105MP0002938_white_spotting0.94398157
106MP0001346_abnormal_lacrimal_gland0.94162577
107MP0003861_abnormal_nervous_system0.94141961
108MP0000678_abnormal_parathyroid_gland0.92114041
109MP0009703_decreased_birth_body0.91288479
110MP0003329_amyloid_beta_deposits0.91114149
111MP0002452_abnormal_antigen_presenting0.90690748
112MP0000432_abnormal_head_morphology0.90558934
113MP0003300_gastrointestinal_ulcer0.89838748
114MP0003091_abnormal_cell_migration0.89315868
115MP0004087_abnormal_muscle_fiber0.88774228
116MP0001186_pigmentation_phenotype0.87902448
117MP0002060_abnormal_skin_morphology0.87506375
118MP0005248_abnormal_Harderian_gland0.86020165
119MP0002114_abnormal_axial_skeleton0.85770043
120MP0000759_abnormal_skeletal_muscle0.85164964
121MP0001873_stomach_inflammation0.84792747
122MP0003935_abnormal_craniofacial_develop0.84741827
123MP0006035_abnormal_mitochondrial_morpho0.84708604
124MP0005058_abnormal_lysosome_morphology0.84509904
125MP0002405_respiratory_system_inflammati0.83740821
126MP0003942_abnormal_urinary_system0.83533660
127MP0005666_abnormal_adipose_tissue0.83237269
128MP0002420_abnormal_adaptive_immunity0.81999352
129MP0000716_abnormal_immune_system0.81937450
130MP0005391_vision/eye_phenotype0.81864576
131MP0003937_abnormal_limbs/digits/tail_de0.81345261
132MP0000762_abnormal_tongue_morphology0.81031477
133MP0001819_abnormal_immune_cell0.80300495
134MP0002429_abnormal_blood_cell0.79683299
135MP0009333_abnormal_splenocyte_physiolog0.78318362
136MP0002925_abnormal_cardiovascular_devel0.78215734
137MP0000749_muscle_degeneration0.77968242
138MP0010155_abnormal_intestine_physiology0.77620016
139MP0002166_altered_tumor_susceptibility0.77355550
140MP0002095_abnormal_skin_pigmentation0.76292263
141MP0004264_abnormal_extraembryonic_tissu0.75737587
142MP0000579_abnormal_nail_morphology0.75464596
143MP0001340_abnormal_eyelid_morphology0.75302888
144MP0003705_abnormal_hypodermis_morpholog0.74919805
145MP0002233_abnormal_nose_morphology0.74849255
146MP0009672_abnormal_birth_weight0.74424238
147MP0000383_abnormal_hair_follicle0.74288974
148MP0001849_ear_inflammation0.73627425
149MP0003453_abnormal_keratinocyte_physiol0.73284242
150MP0003436_decreased_susceptibility_to0.72632448
151MP0006292_abnormal_olfactory_placode0.72366449
152MP0000049_abnormal_middle_ear0.72000386
153MP0003172_abnormal_lysosome_physiology0.69856103
154MP0002009_preneoplasia0.69267062

Predicted human phenotypes

RankGene SetZ-score
1Large earlobe (HP:0009748)4.05884200
2Chromosomal breakage induced by crosslinking agents (HP:0003221)3.54169106
3Chromsome breakage (HP:0040012)3.36248237
4Ependymoma (HP:0002888)3.29051779
5Abnormal number of incisors (HP:0011064)3.19842782
6Short 4th metacarpal (HP:0010044)3.13507243
7Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.13507243
8Skull defect (HP:0001362)3.01323570
9Pseudobulbar signs (HP:0002200)2.98628584
10Esophageal atresia (HP:0002032)2.91294868
11Trigonocephaly (HP:0000243)2.90318933
12Severe visual impairment (HP:0001141)2.87412099
13Selective tooth agenesis (HP:0001592)2.86325153
14Proximal placement of thumb (HP:0009623)2.83222512
15Ulnar bowing (HP:0003031)2.82911418
16Long palpebral fissure (HP:0000637)2.79878054
17Insomnia (HP:0100785)2.67554289
18Premature rupture of membranes (HP:0001788)2.66904129
19Microvesicular hepatic steatosis (HP:0001414)2.66453673
20Deviation of the thumb (HP:0009603)2.63331146
21Cortical dysplasia (HP:0002539)2.57277424
22Heterotopia (HP:0002282)2.52715845
23Increased nuchal translucency (HP:0010880)2.51435151
24Volvulus (HP:0002580)2.51056688
25Protrusio acetabuli (HP:0003179)2.49699150
26Abnormality of the ileum (HP:0001549)2.47520321
27Abnormality of the carotid arteries (HP:0005344)2.45637018
28Abnormality of the fingertips (HP:0001211)2.42487411
29Mesomelia (HP:0003027)2.42381278
30Ectopic kidney (HP:0000086)2.38183856
31Spastic diplegia (HP:0001264)2.37308365
32Progressive external ophthalmoplegia (HP:0000590)2.36900559
33Aplasia/Hypoplasia of the uvula (HP:0010293)2.33301705
34Abnormality of the calcaneus (HP:0008364)2.32690953
35Reticulocytopenia (HP:0001896)2.31446827
36Hyperacusis (HP:0010780)2.30340745
37Pointed chin (HP:0000307)2.29780616
38Medulloblastoma (HP:0002885)2.29734247
39Broad distal phalanx of finger (HP:0009836)2.29723495
40Clubbing of toes (HP:0100760)2.28682806
41Gastrointestinal atresia (HP:0002589)2.28363405
42Abnormal gallbladder physiology (HP:0012438)2.27928551
43Cholecystitis (HP:0001082)2.27928551
44Glioma (HP:0009733)2.26918236
45Cerebral aneurysm (HP:0004944)2.24235251
46Anal stenosis (HP:0002025)2.23705538
47Abdominal situs inversus (HP:0003363)2.19267464
48Abnormality of abdominal situs (HP:0011620)2.19267464
49Abnormality of chromosome stability (HP:0003220)2.18981404
50Meckel diverticulum (HP:0002245)2.18449266
51Abnormality of the preputium (HP:0100587)2.18028012
52Elfin facies (HP:0004428)2.17713792
53Pendular nystagmus (HP:0012043)2.16180515
54Abnormality of the astrocytes (HP:0100707)2.15271909
55Astrocytoma (HP:0009592)2.15271909
56Basal cell carcinoma (HP:0002671)2.12512660
57Shallow orbits (HP:0000586)2.10366890
58Short thumb (HP:0009778)2.10167140
59Deep philtrum (HP:0002002)2.08480384
60High anterior hairline (HP:0009890)2.06700853
61Tracheoesophageal fistula (HP:0002575)2.05433840
62Supernumerary ribs (HP:0005815)2.04546197
63Agnosia (HP:0010524)2.04292622
64Distal lower limb amyotrophy (HP:0008944)2.03283908
65Intestinal atresia (HP:0011100)2.02869399
66Upper limb amyotrophy (HP:0009129)2.02533906
67Distal upper limb amyotrophy (HP:0007149)2.02533906
68Ankyloglossia (HP:0010296)2.01786784
69Disproportionate tall stature (HP:0001519)2.00760289
70Myelodysplasia (HP:0002863)1.99297252
71Premature skin wrinkling (HP:0100678)1.96676584
72Increased connective tissue (HP:0009025)1.95767651
73Abnormality of the 4th metacarpal (HP:0010012)1.95681342
74Neoplasm of the respiratory system (HP:0100606)1.95555492
75Vertebral arch anomaly (HP:0008438)1.95126195
76Squamous cell carcinoma (HP:0002860)1.95070825
77Abnormality of the diencephalon (HP:0010662)1.94499908
78Optic nerve coloboma (HP:0000588)1.94376186
79Poikiloderma (HP:0001029)1.93967022
80Flat acetabular roof (HP:0003180)1.93820612
81Duplicated collecting system (HP:0000081)1.93140769
82Short nail (HP:0001799)1.92550981
83Renovascular hypertension (HP:0100817)1.92127171
84Metaphyseal cupping (HP:0003021)1.92075148
85Biconcave vertebral bodies (HP:0004586)1.91538073
86Turricephaly (HP:0000262)1.89533177
87Supernumerary bones of the axial skeleton (HP:0009144)1.88940902
88Abnormality of the antihelix (HP:0009738)1.87108246
89Renal duplication (HP:0000075)1.86890454
90Generalized hypotonia (HP:0001290)1.85955338
91Abnormality of the lower motor neuron (HP:0002366)1.85785800
92Thin ribs (HP:0000883)1.85606196
93Neoplasm of the pancreas (HP:0002894)1.85171234
94Neoplasm of the adrenal cortex (HP:0100641)1.84083564
95Neoplasm of the oral cavity (HP:0100649)1.83580415
96Skin tags (HP:0010609)1.83492010
97Anteriorly placed anus (HP:0001545)1.82783355
98Broad palm (HP:0001169)1.82475876
99Depressed nasal tip (HP:0000437)1.82361712
100Entropion (HP:0000621)1.82266290
101Centrally nucleated skeletal muscle fibers (HP:0003687)1.81009408
102Bone marrow hypocellularity (HP:0005528)1.80467736
103Termporal pattern (HP:0011008)1.79997082
104Insidious onset (HP:0003587)1.79997082
105Arnold-Chiari malformation (HP:0002308)1.79130232
106Amaurosis fugax (HP:0100576)1.78120733
107Overriding aorta (HP:0002623)1.77963479
108Abnormality of glycolysis (HP:0004366)1.77812409
109Spinal rigidity (HP:0003306)1.76809674
110Embryonal renal neoplasm (HP:0011794)1.76623299
111Vertebral compression fractures (HP:0002953)1.75864096
112Urethral obstruction (HP:0000796)1.75456912
113Abnormality of the incisor (HP:0000676)1.75322967
114Abnormality of the distal phalanx of the thumb (HP:0009617)1.74245507
115Hammertoe (HP:0001765)1.73401782
116Birth length less than 3rd percentile (HP:0003561)1.72781694
117Recurrent cutaneous fungal infections (HP:0011370)1.72743317
118Chronic mucocutaneous candidiasis (HP:0002728)1.72743317
119Lower limb amyotrophy (HP:0007210)1.71521065
120Long eyelashes (HP:0000527)1.71193806
121Abnormality of the renal collecting system (HP:0004742)1.70566693
122Abnormality of oral frenula (HP:0000190)1.70448552
123Persistence of primary teeth (HP:0006335)1.70386805
124Abnormality of DNA repair (HP:0003254)1.70192866
125Upper motor neuron abnormality (HP:0002127)1.69851990
126Hand muscle atrophy (HP:0009130)1.69468244
127Recurrent fungal infections (HP:0002841)1.69107388
128Ragged-red muscle fibers (HP:0003200)1.68741942
129Breast hypoplasia (HP:0003187)1.68009874
130Oligodactyly (hands) (HP:0001180)1.67946577
131Cutaneous melanoma (HP:0012056)1.67825654
132Dislocated radial head (HP:0003083)1.66747440
133Ureteral obstruction (HP:0006000)1.66473527
134Neoplasm of the lung (HP:0100526)1.66378450
135Trismus (HP:0000211)1.66339028
136Nephroblastoma (Wilms tumor) (HP:0002667)1.66309237
137Neoplasm of striated muscle (HP:0009728)1.65856673
138Supranuclear gaze palsy (HP:0000605)1.65527995
139Broad face (HP:0000283)1.65014745
140Small intestinal stenosis (HP:0012848)1.64874977
141Duodenal stenosis (HP:0100867)1.64874977
142Ureteral stenosis (HP:0000071)1.64437748
143Radial bowing (HP:0002986)1.64312946
144Natal tooth (HP:0000695)1.64107308
145Rhizomelia (HP:0008905)1.64016578
146Aplasia involving forearm bones (HP:0009822)1.63625296
147Absent forearm bone (HP:0003953)1.63625296
148Limited elbow extension (HP:0001377)1.63357520
149Cheilitis (HP:0100825)1.62852628
150Abnormality of the thoracic spine (HP:0100711)1.62631260
151Duplication of thumb phalanx (HP:0009942)1.62277888
152Orthostatic hypotension (HP:0001278)1.61658349
153Patellar dislocation (HP:0002999)1.61540888
154Cutis marmorata (HP:0000965)1.60972938
155Chorioretinal atrophy (HP:0000533)1.60638705
156Patellar aplasia (HP:0006443)1.60602502
157Cellular immunodeficiency (HP:0005374)1.60203317
158Adactyly (HP:0009776)1.60192638
159Alacrima (HP:0000522)1.59803822
160Aplasia cutis congenita (HP:0001057)1.59753012
161Absent frontal sinuses (HP:0002688)1.59662866
162Preauricular skin tag (HP:0000384)1.59607807
163Bowel diverticulosis (HP:0005222)1.59080698
164Hypoplasia of the capital femoral epiphysis (HP:0003090)1.57984554
165Advanced eruption of teeth (HP:0006288)1.57826187
166Absent epiphyses (HP:0010577)1.56746657
167Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.56746657
168Abnormality of the salivary glands (HP:0010286)1.56657659
169Missing ribs (HP:0000921)1.56584203
170Choanal stenosis (HP:0000452)1.56443215
171Deformed sella turcica (HP:0002681)1.56026671
172Increased variability in muscle fiber diameter (HP:0003557)1.55561228
173Abnormality of the humeroradial joint (HP:0100744)1.55140908
174Genu recurvatum (HP:0002816)1.55059504
175Breech presentation (HP:0001623)1.54490900
176Congenital hip dislocation (HP:0001374)1.54413483
177Capillary hemangiomas (HP:0005306)1.54085196
178Shoulder girdle muscle weakness (HP:0003547)1.53324168
179Impaired pain sensation (HP:0007328)1.53070786
180Abnormality of pain sensation (HP:0010832)1.53070786
181Pterygium (HP:0001059)1.52004967
182Multiple enchondromatosis (HP:0005701)1.51883113

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PASK9.82850864
2SMG13.90782735
3MAP3K103.58985620
4CAMKK12.91866052
5CDK122.61977467
6PKN22.43350074
7PRPF4B2.27626831
8SIK32.07603497
9PAK41.95771810
10BRD41.88158608
11TSSK61.80098203
12TLK11.79005694
13CDC71.76350481
14NME21.69016082
15EEF2K1.56578510
16BMX1.56456353
17MET1.55197551
18SIK21.54186045
19FLT31.53113998
20NEK11.33160306
21SIK11.32449277
22CDK41.30482543
23MAP4K11.27232572
24NEK21.24598284
25EPHB11.24582442
26ATR1.21690308
27ICK1.20214097
28SCYL21.20040622
29CDK191.18028893
30CLK11.17749381
31MST1R1.17593068
32EPHA21.16804954
33RPS6KA41.15742104
34RIPK11.15275790
35CAMK1G1.13435237
36IRAK41.13043365
37RPS6KB21.12807535
38SRPK11.12449275
39PLK41.12194308
40CDK71.12110430
41PTK21.08770671
42WEE11.08387672
43PBK1.05627420
44STK101.02919524
45TGFBR11.02247224
46PRKD30.99985243
47MAPK70.99512313
48TGFBR20.99469041
49NTRK10.98568247
50ERBB20.98119952
51CHEK10.97104808
52ERN10.94567490
53CDK80.93663554
54TTN0.93654185
55TYRO30.91105095
56MKNK20.90950739
57STK40.86863061
58TXK0.86299598
59PLK10.82791417
60KSR20.81594434
61NEK90.80575377
62PIM10.78025812
63TRIB30.77575917
64TTK0.77088386
65MARK20.75574166
66FGFR40.75384800
67YES10.73927385
68JAK30.73013822
69BUB10.71959106
70MTOR0.71485752
71TESK20.71094238
72ARAF0.70999056
73FGR0.69318529
74CDK90.69049921
75BRAF0.68833892
76LATS20.68599340
77NEK60.68206458
78FGFR30.67867244
79TYK20.66877164
80LMTK20.66549414
81MKNK10.64883173
82AURKA0.64783367
83CDK11A0.63242127
84BTK0.63006418
85MAP2K20.62683447
86ZAK0.62647242
87AURKB0.62272390
88PTK60.62153658
89CDK60.62125430
90RPS6KC10.61598039
91RPS6KL10.61598039
92FGFR10.60059468
93CDK20.58180537
94ALK0.58177684
95HCK0.57770013
96MAP3K60.54645877
97CDK150.54575145
98RET0.54524360
99TAF10.54242570
100RPS6KA60.53862672
101ATM0.53676537
102EIF2AK20.53126160
103EPHB20.53081398
104CSF1R0.52762456
105CHEK20.52155135
106VRK20.51616944
107MELK0.51496437
108BRSK10.51184782
109TESK10.50759719
110CDK180.50571299
111IRAK30.50303772
112AKT20.49670907
113MAPK110.48428917
114DAPK10.47986374
115CAMK1D0.47332683
116PAK20.46496652
117PDGFRB0.46366158
118ILK0.46284349
119MARK30.45375607
120MAP3K130.45259472
121PRKD20.44612368
122MAP2K30.44517722
123CDK140.44484627
124ITK0.44413946
125LATS10.43748784
126RAF10.43673068
127MAP3K80.42140700
128ERBB30.41678431
129DYRK1B0.41339546
130WNK10.40980113
131INSRR0.40311520
132MAP3K90.40039747
133FGFR20.39753398
134LRRK20.38696650
135MAPK140.38045024
136MAP3K70.37772420
137MAPK100.37355545
138CDK10.37009566
139CHUK0.35765863
140RPS6KA20.34661782
141LCK0.34546197
142MAP3K140.33475788
143CSNK1D0.33368351
144EPHA30.33238026
145BCKDK0.32816415
146PDGFRA0.32772559
147CSK0.32695578
148AKT10.32517257
149BRSK20.29799350
150PRKCI0.29547545

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.61278712
2Mismatch repair_Homo sapiens_hsa034303.10895209
3One carbon pool by folate_Homo sapiens_hsa006703.03941766
4Base excision repair_Homo sapiens_hsa034102.84166906
5Biosynthesis of amino acids_Homo sapiens_hsa012302.66612697
6Spliceosome_Homo sapiens_hsa030402.65230815
72-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.62184760
8Homologous recombination_Homo sapiens_hsa034402.41792372
9Fanconi anemia pathway_Homo sapiens_hsa034602.19214520
10Lysine degradation_Homo sapiens_hsa003102.14018179
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.08497033
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.06323518
13Pentose phosphate pathway_Homo sapiens_hsa000301.97534962
14mRNA surveillance pathway_Homo sapiens_hsa030151.94327832
15Notch signaling pathway_Homo sapiens_hsa043301.92402285
16Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.90194041
17MicroRNAs in cancer_Homo sapiens_hsa052061.89489407
18Non-homologous end-joining_Homo sapiens_hsa034501.88049453
19Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.87154446
20RNA transport_Homo sapiens_hsa030131.85763196
21Cell cycle_Homo sapiens_hsa041101.85496236
22Basal cell carcinoma_Homo sapiens_hsa052171.75124216
23p53 signaling pathway_Homo sapiens_hsa041151.71936637
24Carbon metabolism_Homo sapiens_hsa012001.70143002
25Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.69031965
26Nucleotide excision repair_Homo sapiens_hsa034201.60746096
27Primary immunodeficiency_Homo sapiens_hsa053401.55724883
28Fructose and mannose metabolism_Homo sapiens_hsa000511.46310143
29Small cell lung cancer_Homo sapiens_hsa052221.44850295
30Herpes simplex infection_Homo sapiens_hsa051681.38850352
31Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.35255852
32HTLV-I infection_Homo sapiens_hsa051661.27469218
33Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.26025422
34Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.25556049
35NF-kappa B signaling pathway_Homo sapiens_hsa040641.24915798
36RNA degradation_Homo sapiens_hsa030181.23862107
37Chronic myeloid leukemia_Homo sapiens_hsa052201.23109589
38Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.21105284
39Galactose metabolism_Homo sapiens_hsa000521.20272592
40Vitamin B6 metabolism_Homo sapiens_hsa007501.17233676
41Cyanoamino acid metabolism_Homo sapiens_hsa004601.15955592
42Ribosome_Homo sapiens_hsa030101.12785062
43Steroid biosynthesis_Homo sapiens_hsa001001.12236172
44Other glycan degradation_Homo sapiens_hsa005111.12140905
45Transcriptional misregulation in cancer_Homo sapiens_hsa052021.11470588
46Pancreatic cancer_Homo sapiens_hsa052121.08325186
47ErbB signaling pathway_Homo sapiens_hsa040121.07812820
48Colorectal cancer_Homo sapiens_hsa052101.06815299
49Non-small cell lung cancer_Homo sapiens_hsa052231.06032797
50Measles_Homo sapiens_hsa051621.03637834
51Dorso-ventral axis formation_Homo sapiens_hsa043201.03399002
52Thyroid hormone signaling pathway_Homo sapiens_hsa049191.02481003
53Viral carcinogenesis_Homo sapiens_hsa052031.02281766
54Systemic lupus erythematosus_Homo sapiens_hsa053221.01936297
55Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.01741904
56Pyrimidine metabolism_Homo sapiens_hsa002401.00800170
57Prostate cancer_Homo sapiens_hsa052151.00325360
58Bladder cancer_Homo sapiens_hsa052190.96367985
59Hippo signaling pathway_Homo sapiens_hsa043900.96288029
60Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.95844976
61Leishmaniasis_Homo sapiens_hsa051400.95661127
62T cell receptor signaling pathway_Homo sapiens_hsa046600.92989668
63Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.92862364
64Insulin signaling pathway_Homo sapiens_hsa049100.92796396
65Hedgehog signaling pathway_Homo sapiens_hsa043400.90366363
66Apoptosis_Homo sapiens_hsa042100.88457466
67VEGF signaling pathway_Homo sapiens_hsa043700.88348526
68Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.88269187
69Acute myeloid leukemia_Homo sapiens_hsa052210.87573040
70Hepatitis B_Homo sapiens_hsa051610.86171212
71AMPK signaling pathway_Homo sapiens_hsa041520.85440095
72Epstein-Barr virus infection_Homo sapiens_hsa051690.84442430
73Central carbon metabolism in cancer_Homo sapiens_hsa052300.81041685
74NOD-like receptor signaling pathway_Homo sapiens_hsa046210.80712772
75Endometrial cancer_Homo sapiens_hsa052130.80455646
76Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.79027731
77Viral myocarditis_Homo sapiens_hsa054160.78794262
78Basal transcription factors_Homo sapiens_hsa030220.77866306
79Pathways in cancer_Homo sapiens_hsa052000.77436259
80Cysteine and methionine metabolism_Homo sapiens_hsa002700.77244610
81Longevity regulating pathway - mammal_Homo sapiens_hsa042110.76599740
82Influenza A_Homo sapiens_hsa051640.75805461
83Antigen processing and presentation_Homo sapiens_hsa046120.75657283
84Proteoglycans in cancer_Homo sapiens_hsa052050.75360078
85Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.74152251
86B cell receptor signaling pathway_Homo sapiens_hsa046620.74093459
87Melanoma_Homo sapiens_hsa052180.73958358
88Toxoplasmosis_Homo sapiens_hsa051450.73467923
89Adherens junction_Homo sapiens_hsa045200.73198123
90Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.72685922
91Hematopoietic cell lineage_Homo sapiens_hsa046400.72031071
92Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.70055830
93Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.68797806
94Sulfur relay system_Homo sapiens_hsa041220.68729953
95Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.68494183
96Legionellosis_Homo sapiens_hsa051340.68189540
97Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.68079238
98Intestinal immune network for IgA production_Homo sapiens_hsa046720.68027869
99Selenocompound metabolism_Homo sapiens_hsa004500.67055193
100Glycosaminoglycan degradation_Homo sapiens_hsa005310.66522854
101Shigellosis_Homo sapiens_hsa051310.65425869
102Choline metabolism in cancer_Homo sapiens_hsa052310.65334191
103AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65317143
104Renal cell carcinoma_Homo sapiens_hsa052110.65242240
105Leukocyte transendothelial migration_Homo sapiens_hsa046700.65156788
106Pyruvate metabolism_Homo sapiens_hsa006200.62805230
107Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.62576370
108Oocyte meiosis_Homo sapiens_hsa041140.61458733
109Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.61179480
110Jak-STAT signaling pathway_Homo sapiens_hsa046300.60808347
111mTOR signaling pathway_Homo sapiens_hsa041500.58755206
112Axon guidance_Homo sapiens_hsa043600.58310170
113Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.57420140
114Arginine biosynthesis_Homo sapiens_hsa002200.57174765
115Tight junction_Homo sapiens_hsa045300.55372077
116ECM-receptor interaction_Homo sapiens_hsa045120.53960040
117RNA polymerase_Homo sapiens_hsa030200.53807389
118Osteoclast differentiation_Homo sapiens_hsa043800.52466027
119Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.52196109
120Thyroid cancer_Homo sapiens_hsa052160.51687124
121Fatty acid metabolism_Homo sapiens_hsa012120.50434969
122Glucagon signaling pathway_Homo sapiens_hsa049220.49986980
123Neurotrophin signaling pathway_Homo sapiens_hsa047220.49188793
124Wnt signaling pathway_Homo sapiens_hsa043100.48717229
125Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.48168948
126Regulation of actin cytoskeleton_Homo sapiens_hsa048100.47384079
127PI3K-Akt signaling pathway_Homo sapiens_hsa041510.47203738
128HIF-1 signaling pathway_Homo sapiens_hsa040660.46295694
129RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46084398
130FoxO signaling pathway_Homo sapiens_hsa040680.45569377
131Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.45531646
132N-Glycan biosynthesis_Homo sapiens_hsa005100.44083265
133Toll-like receptor signaling pathway_Homo sapiens_hsa046200.43481879
134Phosphatidylinositol signaling system_Homo sapiens_hsa040700.43363292
135Inositol phosphate metabolism_Homo sapiens_hsa005620.43310331
136TGF-beta signaling pathway_Homo sapiens_hsa043500.43213448
137Tuberculosis_Homo sapiens_hsa051520.39810188
138Focal adhesion_Homo sapiens_hsa045100.38649055
139Renin-angiotensin system_Homo sapiens_hsa046140.38087111
140Hepatitis C_Homo sapiens_hsa051600.37508608
141Glioma_Homo sapiens_hsa052140.36903030
142TNF signaling pathway_Homo sapiens_hsa046680.36626472
143Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.36462689
144Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.35104146

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »