MOB3C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.44426445
2positive regulation of gamma-delta T cell activation (GO:0046645)5.23232909
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.18687709
4negative regulation of cell killing (GO:0031342)4.18687709
5modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.98306296
6modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.98306296
7positive regulation by organism of defense response of other organism involved in symbiotic interact3.98306296
8modulation by symbiont of host immune response (GO:0052553)3.98306296
9positive regulation by symbiont of host defense response (GO:0052509)3.98306296
10modulation by symbiont of host defense response (GO:0052031)3.98306296
11daunorubicin metabolic process (GO:0044597)3.98048572
12polyketide metabolic process (GO:0030638)3.98048572
13doxorubicin metabolic process (GO:0044598)3.98048572
14regulation of gamma-delta T cell activation (GO:0046643)3.77621427
15lipopolysaccharide-mediated signaling pathway (GO:0031663)3.55651928
16detection of molecule of bacterial origin (GO:0032490)3.54915378
17regulation of interferon-beta biosynthetic process (GO:0045357)3.45210746
18positive regulation of cellular amide metabolic process (GO:0034250)3.44860640
19regulation of B cell receptor signaling pathway (GO:0050855)3.40997226
20response to peptidoglycan (GO:0032494)3.40419931
21positive regulation of interferon-alpha production (GO:0032727)3.36728408
22regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.36725903
23positive regulation of B cell differentiation (GO:0045579)3.36032936
24regulation of gamma-delta T cell differentiation (GO:0045586)3.31933270
25response to type I interferon (GO:0034340)3.30293441
26detection of other organism (GO:0098543)3.29561072
27cellular response to type I interferon (GO:0071357)3.27210484
28type I interferon signaling pathway (GO:0060337)3.27210484
29antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.23861016
30antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.23861016
31positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.23518202
32interferon-gamma production (GO:0032609)3.23107441
33regulation of interleukin-12 biosynthetic process (GO:0045075)3.22521607
34regulation of T-helper 1 cell differentiation (GO:0045625)3.22085145
35NIK/NF-kappaB signaling (GO:0038061)3.16643535
36regulation of interferon-alpha production (GO:0032647)3.16087231
37response to muramyl dipeptide (GO:0032495)3.15184255
38regulation of T-helper 2 cell differentiation (GO:0045628)3.10685351
39cellular extravasation (GO:0045123)3.09659265
40negative regulation of cytokine production involved in immune response (GO:0002719)3.09511875
41regulation of B cell differentiation (GO:0045577)3.05575189
42positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.04606988
43macrophage activation involved in immune response (GO:0002281)3.01849980
44response to interferon-alpha (GO:0035455)3.01759889
45regulation of vitamin D biosynthetic process (GO:0060556)3.00508761
46microglial cell activation (GO:0001774)2.96653529
47detection of external biotic stimulus (GO:0098581)2.96225686
48negative regulation of myeloid cell apoptotic process (GO:0033033)2.94667973
49positive regulation of type 2 immune response (GO:0002830)2.92667288
50negative regulation of viral genome replication (GO:0045071)2.92458575
51antigen processing and presentation of endogenous antigen (GO:0019883)2.91272340
52response to host immune response (GO:0052572)2.89741271
53response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.89741271
54detection of bacterium (GO:0016045)2.89280028
55positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.88385446
56neutrophil activation involved in immune response (GO:0002283)2.86481718
57regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.86036738
58positive regulation of interferon-beta production (GO:0032728)2.85485993
59leukocyte aggregation (GO:0070486)2.85325703
60myeloid dendritic cell activation (GO:0001773)2.84838339
61positive regulation of antigen processing and presentation (GO:0002579)2.84547698
62T-helper 1 type immune response (GO:0042088)2.83901773
63regulation of T cell tolerance induction (GO:0002664)2.82668609
64regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.80297640
65definitive hemopoiesis (GO:0060216)2.77980288
66macrophage activation (GO:0042116)2.77898014
67detection of biotic stimulus (GO:0009595)2.77133197
68cellular response to thyroid hormone stimulus (GO:0097067)2.76894406
69defense response to protozoan (GO:0042832)2.71882896
70mature B cell differentiation (GO:0002335)2.71544771
71positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.71067945
72positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.70005529
73negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.69724215
74mature B cell differentiation involved in immune response (GO:0002313)2.69489091
75response to interferon-beta (GO:0035456)2.69023084
76energy homeostasis (GO:0097009)2.68736199
77regulation of podosome assembly (GO:0071801)2.68625109
78negative regulation of mast cell activation (GO:0033004)2.66596369
79regulation of tolerance induction (GO:0002643)2.66371091
80regulation of mast cell activation (GO:0033003)2.65794526
81regulation of type 2 immune response (GO:0002828)2.64987387
82negative regulation of interleukin-12 production (GO:0032695)2.64123643
83neutrophil activation (GO:0042119)2.61943403
84B cell mediated immunity (GO:0019724)2.61939777
85regulation of leukocyte degranulation (GO:0043300)2.61795693
86regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.61716809
87positive regulation of T cell mediated cytotoxicity (GO:0001916)2.60637476
88regulation of mononuclear cell migration (GO:0071675)2.60230231
89response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.60027606
90response to host (GO:0075136)2.60027606
91response to host defenses (GO:0052200)2.60027606
92superoxide anion generation (GO:0042554)2.58467929
93regulation of myeloid leukocyte mediated immunity (GO:0002886)2.58037878
94T cell migration (GO:0072678)2.57238252
95pinocytosis (GO:0006907)2.57231577
96positive regulation of chemokine biosynthetic process (GO:0045080)2.57114912
97positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.56403984
98interferon-gamma-mediated signaling pathway (GO:0060333)2.56386676
99positive regulation of mast cell activation (GO:0033005)2.55995507
100negative regulation of T cell mediated immunity (GO:0002710)2.55656958
101positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.55415892
102immunoglobulin mediated immune response (GO:0016064)2.54265609
103germinal center formation (GO:0002467)2.54179854
104production of molecular mediator involved in inflammatory response (GO:0002532)2.53760385
105negative regulation of innate immune response (GO:0045824)2.53408605
106phagocytosis, engulfment (GO:0006911)2.53037118
107response to protozoan (GO:0001562)2.52491092
108regulation of type I interferon-mediated signaling pathway (GO:0060338)2.51806726
109cellular response to interferon-gamma (GO:0071346)2.51201192
110negative regulation of lymphocyte mediated immunity (GO:0002707)2.50417137
111regulation of interleukin-12 production (GO:0032655)2.48613339
112regulation of mast cell activation involved in immune response (GO:0033006)2.48560179
113JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.48018356
114regulation of antigen processing and presentation (GO:0002577)2.47828661
115regulation of membrane protein ectodomain proteolysis (GO:0051043)2.47827005
116regulation of vitamin metabolic process (GO:0030656)2.47690422
117myeloid dendritic cell differentiation (GO:0043011)2.47306210
118negative regulation of leukocyte mediated immunity (GO:0002704)2.46542207
119positive regulation of humoral immune response (GO:0002922)2.46347688
120lymphocyte chemotaxis (GO:0048247)2.45900133
121negative regulation of erythrocyte differentiation (GO:0045647)2.45812275
122cellular response to exogenous dsRNA (GO:0071360)2.44879393
123negative regulation of granulocyte differentiation (GO:0030853)2.44732194
124negative regulation of production of molecular mediator of immune response (GO:0002701)2.44330947
125neutrophil mediated immunity (GO:0002446)2.43078536
126regulation of mast cell degranulation (GO:0043304)2.42603382
127positive regulation of interleukin-1 beta secretion (GO:0050718)2.41334904
128valine metabolic process (GO:0006573)2.40369384
129cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)2.38464296
130antigen processing and presentation via MHC class Ib (GO:0002475)2.38208360
131regulation of dendritic cell antigen processing and presentation (GO:0002604)2.37908555
132myeloid cell activation involved in immune response (GO:0002275)2.37666679
133granulocyte activation (GO:0036230)2.35422960
134I-kappaB kinase/NF-kappaB signaling (GO:0007249)2.35307875
135positive regulation of NF-kappaB import into nucleus (GO:0042346)2.35302023
136myeloid leukocyte activation (GO:0002274)2.34766859
137I-kappaB phosphorylation (GO:0007252)2.32294801
138dendritic cell migration (GO:0036336)2.31352550
139regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.30282059
140megakaryocyte development (GO:0035855)2.28476340

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.94265179
2BP1_19119308_ChIP-ChIP_Hs578T_Human5.36302732
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.27724355
4IRF8_21731497_ChIP-ChIP_J774_Mouse4.13417890
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.90213379
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.84522513
7SCL_19346495_ChIP-Seq_HPC-7_Human3.75587933
8IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.64759559
9IRF8_27001747_Chip-Seq_BMDM_Mouse3.34217770
10SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.29447615
11* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.25932497
12GATA1_22025678_ChIP-Seq_K562_Human2.89724093
13NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.71624246
14STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.65104351
15EGR1_23403033_ChIP-Seq_LIVER_Mouse2.59904917
16RUNX_20019798_ChIP-Seq_JUKART_Human2.51735222
17RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.48771906
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.48008547
19Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.39987440
20NOTCH1_21737748_ChIP-Seq_TLL_Human2.29917620
21NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.27493458
22LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.26419150
23STAT4_19710469_ChIP-ChIP_TH1__Mouse2.23753045
24VDR_21846776_ChIP-Seq_THP-1_Human2.21063455
25MYB_21317192_ChIP-Seq_ERMYB_Mouse2.15782519
26SPI1_23547873_ChIP-Seq_NB4_Human2.09002899
27STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.06061540
28SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.05917902
29FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.00353756
30FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.96133414
31LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.95408261
32MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.94220009
33GATA2_21666600_ChIP-Seq_HMVEC_Human1.94023685
34RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.88277651
35KDM2B_26808549_Chip-Seq_SUP-B15_Human1.87226789
36ELF1_17652178_ChIP-ChIP_JURKAT_Human1.84507374
37ELK3_25401928_ChIP-Seq_HUVEC_Human1.81145916
38EGR1_19374776_ChIP-ChIP_THP-1_Human1.79197490
39THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.73614822
40MYB_26560356_Chip-Seq_TH2_Human1.73091010
41GATA1_19941826_ChIP-Seq_K562_Human1.72802058
42MYB_26560356_Chip-Seq_TH1_Human1.72549662
43TCF7_22412390_ChIP-Seq_EML_Mouse1.69710880
44TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.67865907
45PU_27001747_Chip-Seq_BMDM_Mouse1.63799419
46RARG_19884340_ChIP-ChIP_MEFs_Mouse1.63355441
47LXR_22292898_ChIP-Seq_THP-1_Human1.59617170
48RUNX1_22412390_ChIP-Seq_EML_Mouse1.57529691
49RXR_22158963_ChIP-Seq_LIVER_Mouse1.56727136
50CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.56633851
51BRD4_27068464_Chip-Seq_AML-cells_Mouse1.55805818
52KDM2B_26808549_Chip-Seq_DND41_Human1.52320594
53PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.51787024
54MYC_22102868_ChIP-Seq_BL_Human1.50428705
55GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.49889852
56KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.49244226
57ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.47585315
58SPI1_23127762_ChIP-Seq_K562_Human1.46518146
59ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.45942378
60SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.44824762
61STAT6_21828071_ChIP-Seq_BEAS2B_Human1.39691903
62VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.37675780
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37545116
64MAF_26560356_Chip-Seq_TH1_Human1.36942312
65LXR_22158963_ChIP-Seq_LIVER_Mouse1.34978877
66VDR_24763502_ChIP-Seq_THP-1_Human1.34675480
67GATA2_22383799_ChIP-Seq_G1ME_Mouse1.34218040
68SMAD_19615063_ChIP-ChIP_OVARY_Human1.31397226
69PPARA_22158963_ChIP-Seq_LIVER_Mouse1.31112327
70STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.30907372
71FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.29800955
72MAF_26560356_Chip-Seq_TH2_Human1.29668280
73CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.28568981
74NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.25710318
75PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.23926263
76ESR2_21235772_ChIP-Seq_MCF-7_Human1.23241346
77FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.23214852
78CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.21328657
79NFE2_27457419_Chip-Seq_LIVER_Mouse1.19541783
80PCGF2_27294783_Chip-Seq_ESCs_Mouse1.18176051
81E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.16866142
82GATA1_19941827_ChIP-Seq_MEL_Mouse1.16715333
83KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.16190877
84TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.15470159
85SUZ12_27294783_Chip-Seq_NPCs_Mouse1.15266802
86ERG_20887958_ChIP-Seq_HPC-7_Mouse1.14329850
87VDR_24787735_ChIP-Seq_THP-1_Human1.12107150
88PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.10669842
89FLI1_27457419_Chip-Seq_LIVER_Mouse1.10458929
90GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.10185806
91EZH2_27294783_Chip-Seq_NPCs_Mouse1.09998874
92GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09185732
93RACK7_27058665_Chip-Seq_MCF-7_Human1.08418671
94NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.05652133
95CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.03188853
96GATA1_22383799_ChIP-Seq_G1ME_Mouse1.02804365
97NCOR1_26117541_ChIP-Seq_K562_Human1.02364124
98CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.00516084
99SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00357761
100CTCF_27219007_Chip-Seq_ERYTHROID_Human1.00259046
101UTX_26944678_Chip-Seq_JUKART_Human1.00022504
102TP63_17297297_ChIP-ChIP_HaCaT_Human0.99524382
103HOXB4_20404135_ChIP-ChIP_EML_Mouse0.99051705
104CDX2_20551321_ChIP-Seq_CACO-2_Human0.98912940
105GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98902084
106PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97774002
107GATA3_27048872_Chip-Seq_THYMUS_Human0.97743641
108GATA3_26560356_Chip-Seq_TH2_Human0.97095988
109TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.97059278
110TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.95645176
111RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.94845450
112KDM2B_26808549_Chip-Seq_JURKAT_Human0.94520939
113RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.94349748
114STAT3_18555785_Chip-Seq_ESCs_Mouse0.92275015
115CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.92206011
116KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.91642261
117BCL6_27268052_Chip-Seq_Bcells_Human0.91315149
118BCOR_27268052_Chip-Seq_Bcells_Human0.90672676
119TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.88696062
120PCGF2_27294783_Chip-Seq_NPCs_Mouse0.87790631
121SRF_21415370_ChIP-Seq_HL-1_Mouse0.87691896
122CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.87392451
123GATA2_19941826_ChIP-Seq_K562_Human0.85450785
124PU1_27457419_Chip-Seq_LIVER_Mouse0.84460897
125CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.83031777
126NMYC_18555785_Chip-Seq_ESCs_Mouse0.82403850
127TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.81154252
128ZFX_18555785_Chip-Seq_ESCs_Mouse0.80729918
129PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.80375824
130CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.79069884
131SUZ12_18555785_Chip-Seq_ESCs_Mouse0.78899487
132ESRRB_18555785_Chip-Seq_ESCs_Mouse0.77630099
133CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.77446868
134RUNX1_27457419_Chip-Seq_LIVER_Mouse0.76100835

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation4.49281600
2MP0001835_abnormal_antigen_presentation3.47080957
3MP0003436_decreased_susceptibility_to2.73082188
4MP0004510_myositis2.65282473
5MP0009785_altered_susceptibility_to2.64664883
6MP0005671_abnormal_response_to2.64032440
7MP0002419_abnormal_innate_immunity2.44215639
8MP0001790_abnormal_immune_system2.41596569
9MP0005387_immune_system_phenotype2.41596569
10MP0003724_increased_susceptibility_to2.40888696
11MP0000685_abnormal_immune_system2.39669384
12MP0002148_abnormal_hypersensitivity_rea2.34226698
13MP0003191_abnormal_cellular_cholesterol2.29106512
14MP0005464_abnormal_platelet_physiology2.23974527
15MP0001800_abnormal_humoral_immune2.22801910
16MP0002452_abnormal_antigen_presenting2.19707240
17MP0005000_abnormal_immune_tolerance2.17418751
18MP0005025_abnormal_response_to2.15789270
19MP0002723_abnormal_immune_serum2.12416044
20MP0002396_abnormal_hematopoietic_system2.05319652
21MP0005451_abnormal_body_composition1.98970880
22MP0005174_abnormal_tail_pigmentation1.97206767
23MP0002420_abnormal_adaptive_immunity1.95108344
24MP0001819_abnormal_immune_cell1.94732500
25MP0003763_abnormal_thymus_physiology1.88114960
26MP0006082_CNS_inflammation1.85533030
27MP0003075_altered_response_to1.84677313
28MP0005365_abnormal_bile_salt1.80581280
29MP0001853_heart_inflammation1.74845037
30MP0008004_abnormal_stomach_pH1.71600641
31MP0000015_abnormal_ear_pigmentation1.70513408
32MP0010155_abnormal_intestine_physiology1.62712055
33MP0002405_respiratory_system_inflammati1.62540563
34MP0005075_abnormal_melanosome_morpholog1.62046254
35MP0009764_decreased_sensitivity_to1.58409030
36MP0002398_abnormal_bone_marrow1.57714920
37MP0001845_abnormal_inflammatory_respons1.57593013
38MP0009697_abnormal_copulation1.55770723
39MP0009840_abnormal_foam_cell1.54441453
40MP0000716_abnormal_immune_system1.54199556
41MP0002138_abnormal_hepatobiliary_system1.53256122
42MP0000465_gastrointestinal_hemorrhage1.52361277
43MP0008469_abnormal_protein_level1.51518673
44MP0008260_abnormal_autophagy1.47469283
45MP0001533_abnormal_skeleton_physiology1.46060946
46MP0000689_abnormal_spleen_morphology1.44401073
47MP0001545_abnormal_hematopoietic_system1.42278802
48MP0005397_hematopoietic_system_phenotyp1.42278802
49MP0003453_abnormal_keratinocyte_physiol1.40787386
50MP0000604_amyloidosis1.40431404
51MP0002132_abnormal_respiratory_system1.38958369
52MP0004808_abnormal_hematopoietic_stem1.35187668
53MP0002332_abnormal_exercise_endurance1.34488114
54MP0001873_stomach_inflammation1.33830010
55MP0009278_abnormal_bone_marrow1.30633042
56MP0005670_abnormal_white_adipose1.29576984
57MP0006054_spinal_hemorrhage1.28817650
58MP0005085_abnormal_gallbladder_physiolo1.28506930
59MP0002095_abnormal_skin_pigmentation1.28031352
60MP0002429_abnormal_blood_cell1.27682812
61MP0005166_decreased_susceptibility_to1.27421150
62MP0002166_altered_tumor_susceptibility1.27221135
63MP0002722_abnormal_immune_system1.26724081
64MP0003252_abnormal_bile_duct1.24826188
65MP0004947_skin_inflammation1.24808109
66MP0003806_abnormal_nucleotide_metabolis1.24443033
67MP0003448_altered_tumor_morphology1.24351810
68MP0000490_abnormal_crypts_of1.24233630
69MP0005058_abnormal_lysosome_morphology1.23905449
70MP0009333_abnormal_splenocyte_physiolog1.22127074
71MP0003172_abnormal_lysosome_physiology1.20763714
72MP0002933_joint_inflammation1.20687362
73MP0005360_urolithiasis1.20466289
74MP0000371_diluted_coat_color1.19887444
75MP0004782_abnormal_surfactant_physiolog1.18927155
76MP0002998_abnormal_bone_remodeling1.18776901
77MP0002277_abnormal_respiratory_mucosa1.17299213
78MP0003183_abnormal_peptide_metabolism1.17069114
79MP0005167_abnormal_blood-brain_barrier1.16985772
80MP0005164_abnormal_response_to1.16196693
81MP0003690_abnormal_glial_cell1.15686683
82MP0008875_abnormal_xenobiotic_pharmacok1.14560062
83MP0001851_eye_inflammation1.13605472
84MP0005310_abnormal_salivary_gland1.13146588
85MP0003300_gastrointestinal_ulcer1.12363955
86MP0003091_abnormal_cell_migration1.08928023
87MP0003656_abnormal_erythrocyte_physiolo1.07895190
88MP0004381_abnormal_hair_follicle1.05023043
89MP0002006_tumorigenesis1.04185843
90MP0004264_abnormal_extraembryonic_tissu1.04128241
91MP0006292_abnormal_olfactory_placode1.03728584
92MP0001764_abnormal_homeostasis1.02932081
93MP0000858_altered_metastatic_potential1.02638089
94MP0009763_increased_sensitivity_to1.02568135
95MP0004883_abnormal_blood_vessel1.01954225
96MP0002139_abnormal_hepatobiliary_system1.01474924
97MP0001666_abnormal_nutrient_absorption0.98640196
98MP0004147_increased_porphyrin_level0.98370301
99MP0003828_pulmonary_edema0.94951167
100MP0005165_increased_susceptibility_to0.94825917
101MP0003186_abnormal_redox_activity0.94369396
102MP0002928_abnormal_bile_duct0.93587786
103MP0000703_abnormal_thymus_morphology0.92283595
104MP0003943_abnormal_hepatobiliary_system0.91470035
105MP0002693_abnormal_pancreas_physiology0.91108448
106MP0000249_abnormal_blood_vessel0.90945881
107MP0000609_abnormal_liver_physiology0.90704939
108MP0002254_reproductive_system_inflammat0.90675616
109MP0003566_abnormal_cell_adhesion0.89041440
110MP0000343_altered_response_to0.88579958
111MP0003866_abnormal_defecation0.87805515
112MP0001663_abnormal_digestive_system0.86484563
113MP0001986_abnormal_taste_sensitivity0.85857557
114MP0003329_amyloid_beta_deposits0.84700560
115MP0005023_abnormal_wound_healing0.84413031
116MP0009765_abnormal_xenobiotic_induced0.83103300
117MP0003705_abnormal_hypodermis_morpholog0.82534381
118MP0002877_abnormal_melanocyte_morpholog0.80812597
119MP0005390_skeleton_phenotype0.78787018
120MP0000569_abnormal_digit_pigmentation0.78773484
121MP0003795_abnormal_bone_structure0.77116069
122MP0005666_abnormal_adipose_tissue0.77087785
123MP0008874_decreased_physiological_sensi0.76262420
124MP0001849_ear_inflammation0.74938299
125MP0004130_abnormal_muscle_cell0.73119644
126MP0010329_abnormal_lipoprotein_level0.72845960
127MP0001542_abnormal_bone_strength0.72824651
128MP0003279_aneurysm0.72519260
129MP0003045_fibrosis0.72455482
130MP0003868_abnormal_feces_composition0.71380946
131MP0010368_abnormal_lymphatic_system0.70975873
132MP0001958_emphysema0.63763287
133MP0000920_abnormal_myelination0.60173614
134MP0005535_abnormal_body_temperature0.57682806

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glycolipid metabolism (HP:0010969)4.62853122
2Abnormality of liposaccharide metabolism (HP:0010968)4.62853122
3Abnormality of glycosphingolipid metabolism (HP:0004343)4.62853122
4Recurrent abscess formation (HP:0002722)4.05933243
5Eczematoid dermatitis (HP:0000976)3.87475903
6Recurrent bacterial skin infections (HP:0005406)3.70866682
7Myositis (HP:0100614)3.68606763
8Dysostosis multiplex (HP:0000943)3.52066884
9Optic neuritis (HP:0100653)3.47360926
10Retrobulbar optic neuritis (HP:0100654)3.47360926
11Orchitis (HP:0100796)3.43159597
12Purpura (HP:0000979)3.24369028
13Reduced antithrombin III activity (HP:0001976)3.20399839
14Increased cerebral lipofuscin (HP:0011813)3.15223315
15Recurrent fungal infections (HP:0002841)3.14422052
16Periodontitis (HP:0000704)3.09527125
17Abnormal delayed hypersensitivity skin test (HP:0002963)3.06750241
18Elevated erythrocyte sedimentation rate (HP:0003565)3.05821189
19Loss of speech (HP:0002371)3.04989449
20Joint hemorrhage (HP:0005261)3.04654026
21Prolonged bleeding time (HP:0003010)3.00473134
22Chronic otitis media (HP:0000389)2.88505608
23Petechiae (HP:0000967)2.87722787
24Stomatitis (HP:0010280)2.86156636
25Recurrent viral infections (HP:0004429)2.81900695
26Gingival bleeding (HP:0000225)2.78960459
27Abnormality of macrophages (HP:0004311)2.78427762
28Recurrent gram-negative bacterial infections (HP:0005420)2.77022190
29Recurrent skin infections (HP:0001581)2.76843813
30Systemic lupus erythematosus (HP:0002725)2.74407504
31Renal cortical cysts (HP:0000803)2.73704687
32Epistaxis (HP:0000421)2.69460535
33Disinhibition (HP:0000734)2.68148674
34Chronic mucocutaneous candidiasis (HP:0002728)2.64753559
35Recurrent cutaneous fungal infections (HP:0011370)2.64753559
36Abnormality of polysaccharide metabolism (HP:0011012)2.63719154
37Abnormality of glycosaminoglycan metabolism (HP:0004371)2.63719154
38Abnormality of mucopolysaccharide metabolism (HP:0011020)2.63719154
39Panhypogammaglobulinemia (HP:0003139)2.63475448
40IgM deficiency (HP:0002850)2.61887431
41Spontaneous hematomas (HP:0007420)2.60196597
42Gastrointestinal infarctions (HP:0005244)2.58322350
43Mediastinal lymphadenopathy (HP:0100721)2.57055900
44Increased serum ferritin (HP:0003281)2.54815389
45Urinary glycosaminoglycan excretion (HP:0003541)2.51552504
46Mucopolysacchariduria (HP:0008155)2.51552504
47Increased IgM level (HP:0003496)2.51053441
48Vacuolated lymphocytes (HP:0001922)2.50677142
49Type I transferrin isoform profile (HP:0003642)2.49992840
50Amyloidosis (HP:0011034)2.47865564
51Interstitial pulmonary disease (HP:0006530)2.46931329
52Vasculitis (HP:0002633)2.44624441
53Pustule (HP:0200039)2.44354971
54Axonal loss (HP:0003447)2.41754978
55Meningitis (HP:0001287)2.41236539
56Cheilitis (HP:0100825)2.40099014
57Cellulitis (HP:0100658)2.39849271
58Keratoconjunctivitis sicca (HP:0001097)2.39527547
59Albinism (HP:0001022)2.39500235
60Hepatosplenomegaly (HP:0001433)2.38002088
61Chronic diarrhea (HP:0002028)2.37452700
62Encephalitis (HP:0002383)2.36793539
63Abnormality of T cell physiology (HP:0011840)2.35523498
64Gingivitis (HP:0000230)2.33823997
65Glomerulonephritis (HP:0000099)2.32976718
66Asymmetric septal hypertrophy (HP:0001670)2.32702888
67Neurofibrillary tangles (HP:0002185)2.28207519
68Autoimmune thrombocytopenia (HP:0001973)2.26602734
69Inflammation of the large intestine (HP:0002037)2.26598404
70Urticaria (HP:0001025)2.26231653
71Arterial thrombosis (HP:0004420)2.26092369
72Chest pain (HP:0100749)2.25249306
73T lymphocytopenia (HP:0005403)2.25162486
74Abnormality of iron homeostasis (HP:0011031)2.24115338
75Patchy hypopigmentation of hair (HP:0011365)2.23781813
76Agammaglobulinemia (HP:0004432)2.20410059
77Granulocytopenia (HP:0001913)2.17841204
78Leukocytosis (HP:0001974)2.15109962
79Keratoconjunctivitis (HP:0001096)2.14654659
80Menorrhagia (HP:0000132)2.14561041
81Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.14249969
82Prolonged partial thromboplastin time (HP:0003645)2.13860375
83Abnormal platelet function (HP:0011869)2.13822468
84Impaired platelet aggregation (HP:0003540)2.13822468
85Prostate neoplasm (HP:0100787)2.12964059
86Pulmonary infiltrates (HP:0002113)2.12743661
87Hematochezia (HP:0002573)2.12318970
88Gastrointestinal inflammation (HP:0004386)2.11430660
89Hypergammaglobulinemia (HP:0010702)2.11205339
90Thrombocytosis (HP:0001894)2.10199049
91Abnormality of T cell number (HP:0011839)2.09608885
92Premature loss of primary teeth (HP:0006323)2.08902899
93Nuclear cataract (HP:0100018)2.08229152
94Chromosomal breakage induced by crosslinking agents (HP:0003221)2.08136253
95Abnormality of the vasculature of the conjunctiva (HP:0008054)2.06905003
96Abnormality of the prostate (HP:0008775)2.06526323
97Polycythemia (HP:0001901)2.06393007
98White forelock (HP:0002211)2.04950258
99Abnormal platelet volume (HP:0011876)2.04295497
100Abnormality of the nasal mucosa (HP:0000433)2.04279465
101Eosinophilia (HP:0001880)2.04254980
102Gangrene (HP:0100758)2.04178087
103Pulmonary embolism (HP:0002204)2.03946367
104Colitis (HP:0002583)2.03756741
105Increased neuronal autofluorescent lipopigment (HP:0002074)2.03399831
106Polyneuropathy (HP:0001271)2.03346813
107Abnormal protein glycosylation (HP:0012346)2.00755548
108Abnormal glycosylation (HP:0012345)2.00755548
109Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.00755548
110Abnormal protein N-linked glycosylation (HP:0012347)2.00755548
111Cerebral inclusion bodies (HP:0100314)1.99491875
112Mutism (HP:0002300)1.98327270
113Autoimmune hemolytic anemia (HP:0001890)1.95354330
114Hemoptysis (HP:0002105)1.94701131
115Conjugated hyperbilirubinemia (HP:0002908)1.93308157
116Basal ganglia calcification (HP:0002135)1.92872021
117Osteomyelitis (HP:0002754)1.92719587
118Abnormality of T cells (HP:0002843)1.92126074
119Malnutrition (HP:0004395)1.91608444
120Vertigo (HP:0002321)1.90837846
121Episodic fever (HP:0001954)1.90689573
122Glomerulopathy (HP:0100820)1.88504773
123Clubbing of toes (HP:0100760)1.88313446
124Arthralgia (HP:0002829)1.87181124
125Abnormality of complement system (HP:0005339)1.86999232
126Chromsome breakage (HP:0040012)1.86113352
127Keratitis (HP:0000491)1.86090425
128Abnormality of the pleura (HP:0002103)1.85095485
129Neuronal loss in central nervous system (HP:0002529)1.85091658
130Myocardial infarction (HP:0001658)1.83864236
131Abnormality of eosinophils (HP:0001879)1.83524042
132Recurrent pneumonia (HP:0006532)1.82294732
133Obstructive lung disease (HP:0006536)1.81747323
134Chronic obstructive pulmonary disease (HP:0006510)1.81747323
135Hypoplasia of the thymus (HP:0000778)1.80322406
136Complement deficiency (HP:0004431)1.78250993
137Alveolar cell carcinoma (HP:0006519)1.78238157
138Increased IgE level (HP:0003212)1.76519607
139Joint swelling (HP:0001386)1.76468211
140Osteomalacia (HP:0002749)1.74380171
141Anorexia (HP:0002039)1.72996829
142Bruising susceptibility (HP:0000978)1.71533618
143Generalized aminoaciduria (HP:0002909)1.70649375
144Lymphopenia (HP:0001888)1.70289326
145Hypoplasia of the fovea (HP:0007750)1.69109828
146Aplasia/Hypoplasia of the fovea (HP:0008060)1.69109828
147Recurrent lower respiratory tract infections (HP:0002783)1.68798761
148Hypothermia (HP:0002045)1.68026987
149Syringomyelia (HP:0003396)1.68009891
150Spinal cord lesions (HP:0100561)1.68009891

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK33.12451578
2MAP3K143.06270495
3TXK2.94665828
4IRAK42.72252657
5JAK32.68397477
6PRPF4B2.62766990
7MAP4K12.41639306
8TGFBR22.24453871
9ZAK2.19268779
10KIT2.17190287
11IKBKE2.15778253
12TEC2.12244224
13TYK22.08621852
14MAP2K32.00052769
15TAOK11.99770591
16ZAP701.97635650
17TBK11.92615573
18RIPK11.86511364
19BTK1.80306477
20INSRR1.79890622
21SIK31.77831853
22TAOK31.77569192
23IKBKB1.71928889
24TNIK1.70861273
25NLK1.70176566
26MAP3K111.66738968
27FGR1.64067180
28MAP3K131.63955251
29BLK1.61681638
30NUAK11.61220854
31DDR21.54929864
32ERN11.48440064
33CHUK1.40822194
34CDC42BPA1.36093572
35MAPK151.35616625
36FES1.33984816
37EIF2AK21.33961483
38FLT31.33697297
39MAP3K11.30533598
40JAK11.29696675
41ADRBK21.23491439
42YES11.15655557
43IRAK11.13649404
44TRIB31.11174312
45TAOK21.09372321
46ITK1.08297115
47TIE11.07608543
48LCK1.06131420
49MOS1.04815211
50LYN1.03211862
51STK101.02760131
52TTN1.01781683
53CSF1R1.01550823
54CLK11.01429950
55MARK30.99576980
56CSK0.99003935
57SYK0.98256642
58FGFR40.97670386
59EPHA30.95830026
60BMX0.95734588
61TNK20.95102605
62HCK0.95041917
63PIM10.93934984
64GRK60.89024997
65CDK30.88722698
66PIM20.86082576
67TRPM70.85701918
68SIK10.84986964
69MAP2K60.81472028
70MAPK70.78815738
71KSR20.78583327
72NME20.77823223
73TESK20.77604399
74NEK90.77242543
75BMPR1B0.76737222
76KDR0.76449433
77STK160.75059840
78PIK3CG0.74998867
79PASK0.74312937
80MARK20.71667998
81MATK0.68566467
82PDPK10.68464271
83TESK10.68350330
84MAP3K50.66964509
85TGFBR10.65891394
86GRK70.64985443
87IRAK20.64894661
88PDK10.64234912
89PRKAA20.63832753
90RIPK40.62415821
91CAMK1D0.61744712
92RPS6KA40.61020548
93FGFR30.59319310
94BMPR20.57402929
95PRKG20.56746053
96CDK120.56445800
97PDGFRA0.56303608
98PTK2B0.54171754
99GRK10.53883568
100VRK10.53774643
101JAK20.52903019
102ARAF0.52490597
103EPHA20.52244309
104ABL20.51463581
105CAMKK20.51020808
106STK240.50737407
107MAP3K30.49404033
108EPHB10.49220269
109MAPK120.48531594
110ERBB30.48114004
111MAPK40.47420203
112IGF1R0.47263687
113HIPK20.47027437
114MKNK20.46760548
115MAPK110.46335323
116BCKDK0.45951886
117SIK20.45950739
118ABL10.45737651
119NEK60.45307105
120EIF2AK30.45092296
121SGK20.44497057
122SMG10.43766417
123PRKD20.43503115
124MAPK30.41979595
125MAP3K60.41407530
126PRKCD0.41225314
127PDGFRB0.40528173
128STK30.40481900
129ICK0.40358817
130RPS6KC10.39814785
131RPS6KL10.39814785
132FYN0.39810921
133MAPKAPK20.38236128
134MKNK10.37464190
135PTK60.37388162
136SGK30.34567417
137PRKD10.33153565
138ACVR1B0.31973625
139RPS6KA20.30910828

Predicted pathways (KEGG)

RankGene SetZ-score
1NF-kappa B signaling pathway_Homo sapiens_hsa040642.77011027
2Staphylococcus aureus infection_Homo sapiens_hsa051502.54925989
3Primary immunodeficiency_Homo sapiens_hsa053402.33201053
4Leishmaniasis_Homo sapiens_hsa051402.31482949
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.20600543
6RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.19042303
7Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.14514193
8Measles_Homo sapiens_hsa051622.12547827
9Toll-like receptor signaling pathway_Homo sapiens_hsa046202.07258930
10Intestinal immune network for IgA production_Homo sapiens_hsa046721.84538367
11Hematopoietic cell lineage_Homo sapiens_hsa046401.81802967
12Graft-versus-host disease_Homo sapiens_hsa053321.81124911
13Other glycan degradation_Homo sapiens_hsa005111.79331753
14Osteoclast differentiation_Homo sapiens_hsa043801.78515968
15Maturity onset diabetes of the young_Homo sapiens_hsa049501.75304588
16NOD-like receptor signaling pathway_Homo sapiens_hsa046211.71680059
17Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.60622961
18Herpes simplex infection_Homo sapiens_hsa051681.58180763
19Vitamin digestion and absorption_Homo sapiens_hsa049771.56527401
20ABC transporters_Homo sapiens_hsa020101.56403830
21Complement and coagulation cascades_Homo sapiens_hsa046101.52614390
22Allograft rejection_Homo sapiens_hsa053301.52020249
23Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.51905198
24Type I diabetes mellitus_Homo sapiens_hsa049401.51767803
25Caffeine metabolism_Homo sapiens_hsa002321.50161760
26Glycosaminoglycan degradation_Homo sapiens_hsa005311.49187539
27Legionellosis_Homo sapiens_hsa051341.48089024
28Influenza A_Homo sapiens_hsa051641.45171235
29Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.45130774
30Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.43121973
31Pentose and glucuronate interconversions_Homo sapiens_hsa000401.42931629
32Malaria_Homo sapiens_hsa051441.41518523
33Jak-STAT signaling pathway_Homo sapiens_hsa046301.39516852
34Pertussis_Homo sapiens_hsa051331.38957615
35B cell receptor signaling pathway_Homo sapiens_hsa046621.34417960
36TNF signaling pathway_Homo sapiens_hsa046681.28258527
37Antigen processing and presentation_Homo sapiens_hsa046121.26991636
38Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.20200017
39Toxoplasmosis_Homo sapiens_hsa051451.14322277
40Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.13611627
41Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.13602943
42Protein export_Homo sapiens_hsa030601.11932376
43Transcriptional misregulation in cancer_Homo sapiens_hsa052021.09631701
44Primary bile acid biosynthesis_Homo sapiens_hsa001201.08816283
45Tuberculosis_Homo sapiens_hsa051521.04953108
46Adipocytokine signaling pathway_Homo sapiens_hsa049201.04662651
47Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.04310382
48Steroid hormone biosynthesis_Homo sapiens_hsa001401.03498525
49Autoimmune thyroid disease_Homo sapiens_hsa053201.00080817
50Asthma_Homo sapiens_hsa053100.98469736
51Hepatitis C_Homo sapiens_hsa051600.98446920
52Amoebiasis_Homo sapiens_hsa051460.97546059
53Peroxisome_Homo sapiens_hsa041460.97541108
54Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.97217017
55Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.95626396
56Lysosome_Homo sapiens_hsa041420.94730472
57Arachidonic acid metabolism_Homo sapiens_hsa005900.93375654
58VEGF signaling pathway_Homo sapiens_hsa043700.92868356
59Selenocompound metabolism_Homo sapiens_hsa004500.92679345
60SNARE interactions in vesicular transport_Homo sapiens_hsa041300.91868886
61Folate biosynthesis_Homo sapiens_hsa007900.91696451
62Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.91322745
63Prion diseases_Homo sapiens_hsa050200.90369948
64N-Glycan biosynthesis_Homo sapiens_hsa005100.90021718
65Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.89229771
66Apoptosis_Homo sapiens_hsa042100.89096002
67T cell receptor signaling pathway_Homo sapiens_hsa046600.87440927
68Acute myeloid leukemia_Homo sapiens_hsa052210.85803085
69Rheumatoid arthritis_Homo sapiens_hsa053230.84931108
70Tryptophan metabolism_Homo sapiens_hsa003800.82879544
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.81578683
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.80739433
73Hepatitis B_Homo sapiens_hsa051610.80522132
74Pancreatic cancer_Homo sapiens_hsa052120.80496125
75Non-homologous end-joining_Homo sapiens_hsa034500.80031240
76Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.78788377
77Chemical carcinogenesis_Homo sapiens_hsa052040.77612302
78Bladder cancer_Homo sapiens_hsa052190.77391757
79Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.77058913
80African trypanosomiasis_Homo sapiens_hsa051430.75697030
81Chronic myeloid leukemia_Homo sapiens_hsa052200.75445678
82Shigellosis_Homo sapiens_hsa051310.75307922
83Histidine metabolism_Homo sapiens_hsa003400.74122842
84Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.73481508
85Fanconi anemia pathway_Homo sapiens_hsa034600.73277810
86Retinol metabolism_Homo sapiens_hsa008300.71224169
87Drug metabolism - other enzymes_Homo sapiens_hsa009830.70446744
88Starch and sucrose metabolism_Homo sapiens_hsa005000.70287245
89beta-Alanine metabolism_Homo sapiens_hsa004100.69648842
90Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.68246888
91One carbon pool by folate_Homo sapiens_hsa006700.68087427
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.66776360
93Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.65992632
94Endocytosis_Homo sapiens_hsa041440.65132010
95Notch signaling pathway_Homo sapiens_hsa043300.64978239
96Non-small cell lung cancer_Homo sapiens_hsa052230.63878654
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63801995
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.60790501
99Prolactin signaling pathway_Homo sapiens_hsa049170.60764089
100Sphingolipid metabolism_Homo sapiens_hsa006000.60139299
101Renal cell carcinoma_Homo sapiens_hsa052110.58024216
102Base excision repair_Homo sapiens_hsa034100.57712971
103Galactose metabolism_Homo sapiens_hsa000520.57491191
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57333898
105Insulin resistance_Homo sapiens_hsa049310.56619145
106Leukocyte transendothelial migration_Homo sapiens_hsa046700.56167033
107Chemokine signaling pathway_Homo sapiens_hsa040620.55091327
108Platelet activation_Homo sapiens_hsa046110.53427964
109Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.52989182
110Renin-angiotensin system_Homo sapiens_hsa046140.52389040
111Phospholipase D signaling pathway_Homo sapiens_hsa040720.51678522
112Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51032574
113HIF-1 signaling pathway_Homo sapiens_hsa040660.50746603
114Lysine degradation_Homo sapiens_hsa003100.50563446
115HTLV-I infection_Homo sapiens_hsa051660.48466785
116Homologous recombination_Homo sapiens_hsa034400.46445401
117Type II diabetes mellitus_Homo sapiens_hsa049300.45660488
118Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.45546329
119Epstein-Barr virus infection_Homo sapiens_hsa051690.45224433
120AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.43716982
121Viral carcinogenesis_Homo sapiens_hsa052030.43342263
122GnRH signaling pathway_Homo sapiens_hsa049120.43269503
123FoxO signaling pathway_Homo sapiens_hsa040680.43173114
124PPAR signaling pathway_Homo sapiens_hsa033200.40866920
125Collecting duct acid secretion_Homo sapiens_hsa049660.40125944
126Salmonella infection_Homo sapiens_hsa051320.37470418
127Small cell lung cancer_Homo sapiens_hsa052220.35956941
128Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.35944072
129Phagosome_Homo sapiens_hsa041450.35797297
130mTOR signaling pathway_Homo sapiens_hsa041500.35541254
131Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.35285524
132Viral myocarditis_Homo sapiens_hsa054160.35226746
133Fat digestion and absorption_Homo sapiens_hsa049750.34453613
134MAPK signaling pathway_Homo sapiens_hsa040100.34389876
135Insulin signaling pathway_Homo sapiens_hsa049100.33695412
136Proteoglycans in cancer_Homo sapiens_hsa052050.28893231

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