MOBP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle docking involved in exocytosis (GO:0016081)6.76028922
2fatty acid elongation (GO:0030497)6.72987395
3myelination (GO:0042552)6.62567507
4ensheathment of neurons (GO:0007272)6.62436363
5axon ensheathment (GO:0008366)6.62436363
6glutamate secretion (GO:0014047)6.52238744
7membrane depolarization during cardiac muscle cell action potential (GO:0086012)5.77606518
8cellular potassium ion homeostasis (GO:0030007)5.57543054
9long-chain fatty acid biosynthetic process (GO:0042759)5.37808416
10negative regulation of neurotransmitter secretion (GO:0046929)5.01787259
11sodium ion export (GO:0071436)4.88998232
12neurotransmitter secretion (GO:0007269)4.78233508
13regulation of synaptic vesicle transport (GO:1902803)4.69066722
14negative regulation of neurotransmitter transport (GO:0051589)4.55588648
15myelin maintenance (GO:0043217)4.31726210
16potassium ion homeostasis (GO:0055075)4.26474758
17L-amino acid import (GO:0043092)4.23540101
18oligodendrocyte differentiation (GO:0048709)4.23349492
19glycerophospholipid catabolic process (GO:0046475)4.20731055
20postsynaptic membrane organization (GO:0001941)4.18630670
21vocalization behavior (GO:0071625)4.17462752
22potassium ion import (GO:0010107)4.17063843
23negative regulation of synaptic transmission, GABAergic (GO:0032229)4.15861161
24peptidyl-tyrosine autophosphorylation (GO:0038083)4.12226655
25cholesterol biosynthetic process (GO:0006695)4.09560318
26positive regulation of synapse maturation (GO:0090129)4.06565065
27synaptic transmission, glutamatergic (GO:0035249)4.05410696
28regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.03600545
29transmission of nerve impulse (GO:0019226)3.98444096
30establishment of mitochondrion localization (GO:0051654)3.96786729
31negative regulation of protein localization to cell surface (GO:2000009)3.96543364
32regulation of long-term neuronal synaptic plasticity (GO:0048169)3.95704329
33substantia nigra development (GO:0021762)3.94699596
34positive regulation of dendritic spine development (GO:0060999)3.94372568
35neurotransmitter transport (GO:0006836)3.94154716
36presynaptic membrane organization (GO:0097090)3.91996586
37astrocyte development (GO:0014002)3.86643819
38regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.86087321
39creatine metabolic process (GO:0006600)3.85533261
40apical protein localization (GO:0045176)3.84946799
41regulation of collateral sprouting (GO:0048670)3.79079646
42cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.79038756
43cerebellar Purkinje cell differentiation (GO:0021702)3.78456930
44exploration behavior (GO:0035640)3.78137262
45presynaptic membrane assembly (GO:0097105)3.77204002
46regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.75456305
47glutamate receptor signaling pathway (GO:0007215)3.73658957
48neuronal action potential propagation (GO:0019227)3.73391722
49regulation of glutamate receptor signaling pathway (GO:1900449)3.72933736
50asymmetric protein localization (GO:0008105)3.69993795
51regulation of neurotransmitter levels (GO:0001505)3.67828776
52adult walking behavior (GO:0007628)3.66203903
53protein localization to synapse (GO:0035418)3.61424827
54eye photoreceptor cell differentiation (GO:0001754)3.61317029
55photoreceptor cell differentiation (GO:0046530)3.61317029
56regulation of synaptic plasticity (GO:0048167)3.60961084
57positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.58219487
58negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.58210636
59neurotransmitter-gated ion channel clustering (GO:0072578)3.57503548
60regulation of excitatory postsynaptic membrane potential (GO:0060079)3.56955340
61sterol biosynthetic process (GO:0016126)3.56825456
62neuronal ion channel clustering (GO:0045161)3.53995905
63regulation of neurotransmitter secretion (GO:0046928)3.51720047
64acidic amino acid transport (GO:0015800)3.51079523
65adhesion of symbiont to host cell (GO:0044650)3.45051920
66virion attachment to host cell (GO:0019062)3.45051920
67neuromuscular process controlling balance (GO:0050885)3.44493302
68long-term synaptic potentiation (GO:0060291)3.43728861
69long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.42999477
70response to methylmercury (GO:0051597)3.42265825
71peripheral nervous system axon ensheathment (GO:0032292)3.40603552
72myelination in peripheral nervous system (GO:0022011)3.40603552
73regulation of synapse structural plasticity (GO:0051823)3.35521521
74regulation of neurotransmitter transport (GO:0051588)3.34151392
75synaptic vesicle maturation (GO:0016188)3.33709463
76regulation of dendritic spine development (GO:0060998)3.32705606
77membrane depolarization during action potential (GO:0086010)3.32007299
78regulation of synapse maturation (GO:0090128)3.31039731
79negative regulation of axonogenesis (GO:0050771)3.30566703
80regulation of postsynaptic membrane potential (GO:0060078)3.28690248
81cellular sodium ion homeostasis (GO:0006883)3.27963705
82phosphorelay signal transduction system (GO:0000160)3.26570362
83response to redox state (GO:0051775)3.23172065
84synaptic vesicle endocytosis (GO:0048488)3.22377243
85neuron cell-cell adhesion (GO:0007158)3.22151786
86negative regulation of inclusion body assembly (GO:0090084)3.19622032
87membrane tubulation (GO:0097320)3.19257351
88cell communication by electrical coupling (GO:0010644)3.19254440
89amyloid precursor protein metabolic process (GO:0042982)3.17048995
90long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.16368478
91isoprenoid biosynthetic process (GO:0008299)3.16296637
92L-glutamate transport (GO:0015813)3.15740530
93import into cell (GO:0098657)3.14234310
94regulation of ARF protein signal transduction (GO:0032012)3.14130048
95auditory behavior (GO:0031223)3.13725166
96positive regulation of action potential (GO:0045760)3.13695301
97amino acid import (GO:0043090)3.13030026
98positive regulation of oligodendrocyte differentiation (GO:0048714)3.11159099
99membrane depolarization (GO:0051899)3.09437936
100regulation of synaptic transmission (GO:0050804)3.04879172
101regulation of vesicle fusion (GO:0031338)3.03578259
102protein palmitoylation (GO:0018345)3.03465690
103regulation of synaptic transmission, glutamatergic (GO:0051966)3.01990796
104long-term memory (GO:0007616)3.01879702
105glycosylceramide metabolic process (GO:0006677)3.00167082
106positive regulation of dendrite development (GO:1900006)2.99540736
107synaptic transmission (GO:0007268)2.99215297
108negative regulation of dendrite morphogenesis (GO:0050774)2.98622986
109dendritic spine morphogenesis (GO:0060997)2.96942411
110glycine transport (GO:0015816)2.96399291
111cerebellar granule cell differentiation (GO:0021707)2.96214651
112nerve growth factor signaling pathway (GO:0038180)2.95869331
113positive regulation of Rap GTPase activity (GO:0032854)2.95616010
114response to lipoprotein particle (GO:0055094)2.95253739
115fatty-acyl-CoA biosynthetic process (GO:0046949)2.94799695
116positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.94577625
117neuromuscular synaptic transmission (GO:0007274)2.94446968
118cell differentiation in hindbrain (GO:0021533)2.92466386
119proline transport (GO:0015824)2.87998215
120neuromuscular process controlling posture (GO:0050884)2.87223539
121neuromuscular process (GO:0050905)2.87003323
122magnesium ion transport (GO:0015693)2.86593229
123cellular response to epinephrine stimulus (GO:0071872)2.86086034
124cerebral cortex radially oriented cell migration (GO:0021799)2.84729709
125neurotransmitter catabolic process (GO:0042135)2.84506342
126regulation of short-term neuronal synaptic plasticity (GO:0048172)2.81179553
127positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.75280536
128gamma-aminobutyric acid transport (GO:0015812)2.74162758
129regulation of synaptic vesicle exocytosis (GO:2000300)2.73575898
130fatty-acyl-CoA metabolic process (GO:0035337)2.72969897
131peptidyl-cysteine modification (GO:0018198)2.70560289
132negative regulation of axon extension (GO:0030517)2.70205417
133cyclic nucleotide catabolic process (GO:0009214)2.69826534
134axon development (GO:0061564)2.69294626
135negative regulation of JUN kinase activity (GO:0043508)2.68586597
136regulation of dopamine metabolic process (GO:0042053)2.67165735
137regulation of catecholamine metabolic process (GO:0042069)2.67165735
138synaptic vesicle exocytosis (GO:0016079)2.66807143
139locomotory exploration behavior (GO:0035641)2.64699281
140peripheral nervous system development (GO:0007422)2.64539621
141neural nucleus development (GO:0048857)2.64363685
142regulation of voltage-gated calcium channel activity (GO:1901385)2.62145950
143ionotropic glutamate receptor signaling pathway (GO:0035235)2.61363928
144cellular response to catecholamine stimulus (GO:0071870)2.57307663
145cellular response to monoamine stimulus (GO:0071868)2.57307663
146membrane assembly (GO:0071709)2.55864917
147mating behavior (GO:0007617)2.54914040
148regulation of dendritic spine morphogenesis (GO:0061001)2.53421480
149neurotransmitter uptake (GO:0001504)2.53261175
150negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.52954130
151regulation of neuronal synaptic plasticity (GO:0048168)2.52592051
152response to epinephrine (GO:0071871)2.52455614
153neuron remodeling (GO:0016322)2.51915105
154positive regulation of membrane potential (GO:0045838)2.51638866
155Golgi to endosome transport (GO:0006895)2.50898459
156neuron-neuron synaptic transmission (GO:0007270)2.50715417
157very long-chain fatty acid metabolic process (GO:0000038)2.49008646
158neuron recognition (GO:0008038)2.48787188
159adult locomotory behavior (GO:0008344)2.47988058
160gamma-aminobutyric acid signaling pathway (GO:0007214)2.47847776
161adhesion of symbiont to host (GO:0044406)2.45696046
162central nervous system myelination (GO:0022010)10.0485605
163axon ensheathment in central nervous system (GO:0032291)10.0485605

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.38325861
2EZH2_22144423_ChIP-Seq_EOC_Human3.08380913
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.69374883
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.69266985
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.63093824
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.37247943
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.37247943
8MTF2_20144788_ChIP-Seq_MESCs_Mouse2.35941522
9* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.32225670
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.28287538
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.26152189
12DROSHA_22980978_ChIP-Seq_HELA_Human2.24838432
13CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.24319533
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.23440132
15EZH2_27294783_Chip-Seq_ESCs_Mouse2.13567384
16RARB_27405468_Chip-Seq_BRAIN_Mouse2.12987065
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.12391596
18TAF15_26573619_Chip-Seq_HEK293_Human2.11189273
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.10079230
20JARID2_20075857_ChIP-Seq_MESCs_Mouse2.09252554
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.06580401
22EED_16625203_ChIP-ChIP_MESCs_Mouse1.99564248
23VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.87085145
24RNF2_27304074_Chip-Seq_ESCs_Mouse1.86672444
25* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.75851454
26* REST_21632747_ChIP-Seq_MESCs_Mouse1.73648403
27RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.72823118
28AR_21572438_ChIP-Seq_LNCaP_Human1.70049153
29SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.69450136
30RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.55351345
31ER_23166858_ChIP-Seq_MCF-7_Human1.52698498
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.51667879
33ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.48973489
34CDX2_19796622_ChIP-Seq_MESCs_Mouse1.47881972
35* REST_18959480_ChIP-ChIP_MESCs_Mouse1.46861401
36SMAD3_21741376_ChIP-Seq_EPCs_Human1.46210845
37TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44928800
38RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41749085
39PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.40121918
40CTBP1_25329375_ChIP-Seq_LNCAP_Human1.39990844
41GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.38097076
42THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.37588156
43CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.37041563
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.35959605
45SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.29778455
46P53_22127205_ChIP-Seq_FIBROBLAST_Human1.29075607
47SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28599242
48PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.27915763
49CTBP2_25329375_ChIP-Seq_LNCAP_Human1.26016479
50CTNNB1_20460455_ChIP-Seq_HCT116_Human1.25421010
51VDR_22108803_ChIP-Seq_LS180_Human1.25137862
52TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24777698
53E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.23322694
54AR_19668381_ChIP-Seq_PC3_Human1.22805182
55MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.21521894
56STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.20842978
57PIAS1_25552417_ChIP-Seq_VCAP_Human1.20222766
58POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19011553
59* STAT3_23295773_ChIP-Seq_U87_Human1.15350045
60WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15173697
61ERG_21242973_ChIP-ChIP_JURKAT_Human1.12671650
62P300_19829295_ChIP-Seq_ESCs_Human1.11898886
63BMI1_23680149_ChIP-Seq_NPCS_Mouse1.11608607
64SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.11227249
65KDM2B_26808549_Chip-Seq_K562_Human1.08784167
66YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07360071
67GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06318052
68SMAD4_21799915_ChIP-Seq_A2780_Human1.05200391
69SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04509492
70GATA1_26923725_Chip-Seq_HPCs_Mouse1.04232179
71ESR2_21235772_ChIP-Seq_MCF-7_Human1.04127205
72CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.04123338
73RING1B_27294783_Chip-Seq_ESCs_Mouse1.03615010
74SMAD3_21741376_ChIP-Seq_ESCs_Human1.03156396
75NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.02150248
76LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01808885
77TCF4_23295773_ChIP-Seq_U87_Human1.01537459
78FUS_26573619_Chip-Seq_HEK293_Human1.01491903
79WT1_19549856_ChIP-ChIP_CCG9911_Human1.00436638
80EP300_21415370_ChIP-Seq_HL-1_Mouse1.00334293
81EOMES_21245162_ChIP-Seq_HESCs_Human0.99315222
82RING1B_27294783_Chip-Seq_NPCs_Mouse0.98772829
83SMAD4_21741376_ChIP-Seq_HESCs_Human0.98671164
84TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.98063865
85NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.97641653
86NRF2_20460467_ChIP-Seq_MEFs_Mouse0.97641653
87SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.97403916
88TOP2B_26459242_ChIP-Seq_MCF-7_Human0.96520442
89SOX2_21211035_ChIP-Seq_LN229_Gbm0.96434583
90BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.96172336
91* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95445243
92ZFP281_27345836_Chip-Seq_ESCs_Mouse0.95213815
93MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95057204
94RNF2_27304074_Chip-Seq_NSC_Mouse0.94621626
95IKZF1_21737484_ChIP-ChIP_HCT116_Human0.94534130
96TET1_21490601_ChIP-Seq_MESCs_Mouse0.94327727
97CMYC_18555785_Chip-Seq_ESCs_Mouse0.94098256
98* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.93759164
99PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.93755662
100PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.93618174
101TP53_16413492_ChIP-PET_HCT116_Human0.92931785
102NR3C1_23031785_ChIP-Seq_PC12_Mouse0.92505684
103NANOG_18555785_Chip-Seq_ESCs_Mouse0.92233881
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.92228360
105SMAD3_21741376_ChIP-Seq_HESCs_Human0.91729218
106AHR_22903824_ChIP-Seq_MCF-7_Human0.91349436
107* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91223965
108EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.91053516
109LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90334663
110TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.90334633
111ZNF217_24962896_ChIP-Seq_MCF-7_Human0.90324972
112EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.89977969
113EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.89525046
114PRDM14_20953172_ChIP-Seq_ESCs_Human0.89331212
115HTT_18923047_ChIP-ChIP_STHdh_Human0.89312415
116NR3C1_21868756_ChIP-Seq_MCF10A_Human0.88849133
117CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88076321
118TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88014633
119POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.88014633
120TAL1_26923725_Chip-Seq_HPCs_Mouse0.87939526
121TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.87181466
122ZFP281_18757296_ChIP-ChIP_E14_Mouse0.86535050
123SMAD4_21741376_ChIP-Seq_EPCs_Human0.86212208
124TBL1_22424771_ChIP-Seq_293T_Human0.85319779
125RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.85076991
126UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.84908545
127P300_18555785_Chip-Seq_ESCs_Mouse0.84887921
128ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.84502166
129DNAJC2_21179169_ChIP-ChIP_NT2_Human0.84271357

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0000920_abnormal_myelination4.69514476
2MP0003880_abnormal_central_pattern4.62945476
3MP0004859_abnormal_synaptic_plasticity4.04046244
4MP0004270_analgesia3.86138078
5MP0003690_abnormal_glial_cell3.17151432
6MP0002272_abnormal_nervous_system2.90321869
7MP0001486_abnormal_startle_reflex2.85172542
8MP0002064_seizures2.84872330
9MP0004885_abnormal_endolymph2.80294110
10MP0003635_abnormal_synaptic_transmissio2.74039911
11MP0003329_amyloid_beta_deposits2.74021069
12MP0001529_abnormal_vocalization2.70698955
13MP0009046_muscle_twitch2.57860093
14MP0009745_abnormal_behavioral_response2.57260969
15MP0003950_abnormal_plasma_membrane2.50076768
16MP0001905_abnormal_dopamine_level2.43554812
17MP0002822_catalepsy2.35084570
18MP0004742_abnormal_vestibular_system2.33580242
19MP0005423_abnormal_somatic_nervous2.32368686
20MP0004142_abnormal_muscle_tone2.24809528
21MP0003634_abnormal_glial_cell2.21702531
22MP0002734_abnormal_mechanical_nocicepti2.13419044
23MP0001485_abnormal_pinna_reflex2.11587254
24MP0000778_abnormal_nervous_system2.06725799
25MP0002063_abnormal_learning/memory/cond2.05299371
26MP0003879_abnormal_hair_cell1.96658160
27MP0005409_darkened_coat_color1.94612922
28MP0002572_abnormal_emotion/affect_behav1.90077731
29MP0005171_absent_coat_pigmentation1.86730440
30MP0002229_neurodegeneration1.84813226
31MP0003632_abnormal_nervous_system1.77614290
32MP0003787_abnormal_imprinting1.70896987
33MP0001440_abnormal_grooming_behavior1.70508350
34MP0008569_lethality_at_weaning1.68302358
35MP0000955_abnormal_spinal_cord1.66232293
36MP0005410_abnormal_fertilization1.54190036
37MP0002882_abnormal_neuron_morphology1.52465088
38MP0003136_yellow_coat_color1.52114542
39MP0004924_abnormal_behavior1.51144547
40MP0005386_behavior/neurological_phenoty1.51144547
41MP0005451_abnormal_body_composition1.47674630
42MP0002067_abnormal_sensory_capabilities1.47162636
43MP0002066_abnormal_motor_capabilities/c1.47034693
44MP0001970_abnormal_pain_threshold1.46734020
45MP0003631_nervous_system_phenotype1.46136839
46MP0000604_amyloidosis1.40042996
47MP0001968_abnormal_touch/_nociception1.37622369
48MP0004043_abnormal_pH_regulation1.36029592
49MP0003633_abnormal_nervous_system1.35772935
50MP0002733_abnormal_thermal_nociception1.33175566
51MP0010678_abnormal_skin_adnexa1.31614455
52MP0005551_abnormal_eye_electrophysiolog1.30595802
53MP0005167_abnormal_blood-brain_barrier1.29521551
54MP0001501_abnormal_sleep_pattern1.28280900
55MP0000462_abnormal_digestive_system1.24811335
56MP0001963_abnormal_hearing_physiology1.16189716
57MP0000747_muscle_weakness1.09499630
58MP0004147_increased_porphyrin_level1.08525133
59MP0001299_abnormal_eye_distance/1.08223786
60MP0002752_abnormal_somatic_nervous1.07784087
61MP0005623_abnormal_meninges_morphology1.06672388
62MP0000383_abnormal_hair_follicle1.06142598
63MP0004811_abnormal_neuron_physiology1.05229096
64MP0001177_atelectasis1.02515672
65MP0002736_abnormal_nociception_after1.01045452
66MP0000569_abnormal_digit_pigmentation0.99896031
67MP0002557_abnormal_social/conspecific_i0.98823670
68MP0002152_abnormal_brain_morphology0.97489858
69MP0002735_abnormal_chemical_nociception0.96446840
70MP0003122_maternal_imprinting0.95498350
71MP0003123_paternal_imprinting0.95276729
72MP0000566_synostosis0.93646022
73MP0002184_abnormal_innervation0.93638439
74MP0004134_abnormal_chest_morphology0.90814933
75MP0005058_abnormal_lysosome_morphology0.89904648
76MP0001346_abnormal_lacrimal_gland0.88793026
77MP0008877_abnormal_DNA_methylation0.85496465
78MP0003195_calcinosis0.85120164
79MP0002638_abnormal_pupillary_reflex0.84597593
80MP0004381_abnormal_hair_follicle0.84516000
81MP0003806_abnormal_nucleotide_metabolis0.83597691
82MP0004145_abnormal_muscle_electrophysio0.82148114
83MP0005646_abnormal_pituitary_gland0.80998853
84MP0001986_abnormal_taste_sensitivity0.79984102
85MP0001502_abnormal_circadian_rhythm0.79432377
86MP0003075_altered_response_to0.77688180
87MP0008260_abnormal_autophagy0.77485817
88MP0002090_abnormal_vision0.75524349
89MP0008874_decreased_physiological_sensi0.73890060
90MP0003938_abnormal_ear_development0.73103180
91MP0005195_abnormal_posterior_eye0.72248374
92MP0001851_eye_inflammation0.71548479
93MP0008872_abnormal_physiological_respon0.71535162
94MP0003045_fibrosis0.71214712
95MP0006072_abnormal_retinal_apoptosis0.70713019
96MP0001661_extended_life_span0.70022719
97MP0009780_abnormal_chondrocyte_physiolo0.69308058
98MP0003137_abnormal_impulse_conducting0.68080836
99MP0002909_abnormal_adrenal_gland0.67572972
100MP0000026_abnormal_inner_ear0.65556312
101MP0005253_abnormal_eye_physiology0.64119136
102MP0000579_abnormal_nail_morphology0.64091164
103MP0010386_abnormal_urinary_bladder0.63163492
104MP0005645_abnormal_hypothalamus_physiol0.61981313
105MP0000647_abnormal_sebaceous_gland0.61589804
106MP0005535_abnormal_body_temperature0.60112325
107MP0001984_abnormal_olfaction0.59969435
108MP0004130_abnormal_muscle_cell0.59301436
109MP0001348_abnormal_lacrimal_gland0.58672899
110MP0002069_abnormal_eating/drinking_beha0.57453461
111MP0002295_abnormal_pulmonary_circulatio0.57363676
112MP0004085_abnormal_heartbeat0.56652035
113MP0010769_abnormal_survival0.54997507
114MP0001943_abnormal_respiration0.54813395
115MP0004036_abnormal_muscle_relaxation0.54378214
116MP0001727_abnormal_embryo_implantation0.52936694
117MP0006276_abnormal_autonomic_nervous0.52201541
118MP0002082_postnatal_lethality0.51762186
119MP0010770_preweaning_lethality0.51762186
120MP0010768_mortality/aging0.51301323
121MP0000467_abnormal_esophagus_morphology0.50945243
122MP0004215_abnormal_myocardial_fiber0.47058243
123MP0000639_abnormal_adrenal_gland0.44995888
124MP0002089_abnormal_postnatal_growth/wei0.44820901
125MP0003956_abnormal_body_size0.44738132
126MP0000631_abnormal_neuroendocrine_gland0.44020965
127MP0003861_abnormal_nervous_system0.43040794

Predicted human phenotypes

RankGene SetZ-score
1Degeneration of the lateral corticospinal tracts (HP:0002314)6.25190392
2Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)6.25190392
3Neurofibrillary tangles (HP:0002185)6.20664441
4Febrile seizures (HP:0002373)5.06270157
5Abnormality of the corticospinal tract (HP:0002492)4.89284110
6Sensory axonal neuropathy (HP:0003390)4.83305415
7Diplopia (HP:0000651)4.73014840
8Abnormality of binocular vision (HP:0011514)4.73014840
9Myokymia (HP:0002411)4.70872618
10Supranuclear gaze palsy (HP:0000605)4.53164574
11Cerebral inclusion bodies (HP:0100314)4.51858910
12Peripheral hypomyelination (HP:0007182)4.44220561
13Parakeratosis (HP:0001036)4.44196704
14Spastic gait (HP:0002064)4.10227082
15Intention tremor (HP:0002080)3.97785581
16Cerebral hypomyelination (HP:0006808)3.81414666
17Dysmetria (HP:0001310)3.80052706
18Onion bulb formation (HP:0003383)3.79991456
19Generalized tonic-clonic seizures (HP:0002069)3.64254170
20Abnormal eating behavior (HP:0100738)3.55826095
21Focal motor seizures (HP:0011153)3.47923127
22Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.47695187
23Ankle clonus (HP:0011448)3.40547950
24Scanning speech (HP:0002168)3.35408696
25Visual hallucinations (HP:0002367)3.25233241
26Termporal pattern (HP:0011008)3.24100512
27Insidious onset (HP:0003587)3.24100512
28Akinesia (HP:0002304)3.20460619
29Slow saccadic eye movements (HP:0000514)3.14207866
30Abnormal auditory evoked potentials (HP:0006958)3.05200489
31Hemiplegia (HP:0002301)2.97727361
32Hemiparesis (HP:0001269)2.97318098
33Limb dystonia (HP:0002451)2.96277428
34Papilledema (HP:0001085)2.94367183
35Truncal ataxia (HP:0002078)2.91030205
36Alacrima (HP:0000522)2.86880998
37Torticollis (HP:0000473)2.80067484
38Action tremor (HP:0002345)2.76937354
39Obstructive sleep apnea (HP:0002870)2.75861616
40Atonic seizures (HP:0010819)2.70692923
41Increased circulating renin level (HP:0000848)2.70183110
42Leukodystrophy (HP:0002415)2.70151876
43Epileptiform EEG discharges (HP:0011182)2.67654655
44Retinal dysplasia (HP:0007973)2.64841084
45Abnormality of glycolysis (HP:0004366)2.64350279
46Increased serum pyruvate (HP:0003542)2.64350279
47Spastic paraparesis (HP:0002313)2.63126526
48Status epilepticus (HP:0002133)2.60724042
49Bundle branch block (HP:0011710)2.60526372
50Mutism (HP:0002300)2.60076418
51Focal seizures (HP:0007359)2.52183028
52Tetraplegia (HP:0002445)2.51998552
53Poor eye contact (HP:0000817)2.51904689
54Thickened helices (HP:0000391)2.50464284
55Delusions (HP:0000746)2.50352887
56Pheochromocytoma (HP:0002666)2.50238192
57Sleep apnea (HP:0010535)2.46953854
58Lower limb muscle weakness (HP:0007340)2.43700987
59Cerebral hemorrhage (HP:0001342)2.42268921
60Epileptic encephalopathy (HP:0200134)2.42093007
61Megalencephaly (HP:0001355)2.42085055
62Bradykinesia (HP:0002067)2.41822671
63Congenital ichthyosiform erythroderma (HP:0007431)2.40904818
64CNS hypomyelination (HP:0003429)2.40582900
65Annular pancreas (HP:0001734)2.37100519
66Anteriorly placed anus (HP:0001545)2.36554171
67Spastic tetraparesis (HP:0001285)2.35680303
68Depression (HP:0000716)2.33063757
69Focal dystonia (HP:0004373)2.30623229
70Clonus (HP:0002169)2.30603441
71Urinary urgency (HP:0000012)2.30558512
72Hypoplastic pelvis (HP:0008839)2.30088268
73EEG with generalized epileptiform discharges (HP:0011198)2.27234800
74Rigidity (HP:0002063)2.24646363
75Morphological abnormality of the inner ear (HP:0011390)2.23543295
76Autoamputation (HP:0001218)2.23407127
77Dysdiadochokinesis (HP:0002075)2.23315419
78Hyperventilation (HP:0002883)2.23017206
79Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.20941306
80Decreased lacrimation (HP:0000633)2.19198784
81Apathy (HP:0000741)2.17011246
82Clumsiness (HP:0002312)2.16804237
83Impaired smooth pursuit (HP:0007772)2.16658933
84Neuroendocrine neoplasm (HP:0100634)2.16117913
85Absent septum pellucidum (HP:0001331)2.14967844
86Craniofacial dystonia (HP:0012179)2.13816898
87Abnormality of the periventricular white matter (HP:0002518)2.13596991
88Insomnia (HP:0100785)2.13474935
89Metabolic alkalosis (HP:0200114)2.13365464
90Gaze-evoked nystagmus (HP:0000640)2.12652407
91Stridor (HP:0010307)2.10840056
92Urinary bladder sphincter dysfunction (HP:0002839)2.10347913
93Premature skin wrinkling (HP:0100678)2.10067788
94Genetic anticipation (HP:0003743)2.09621815
95Aplasia involving bones of the upper limbs (HP:0009823)2.09430097
96Aplasia of the phalanges of the hand (HP:0009802)2.09430097
97Aplasia involving bones of the extremities (HP:0009825)2.09430097
98Hypsarrhythmia (HP:0002521)2.09160328
99Spastic paraplegia (HP:0001258)2.09072792
100Paraplegia (HP:0010550)2.09044902
101Abnormal social behavior (HP:0012433)2.08891861
102Impaired social interactions (HP:0000735)2.08891861
103Polyphagia (HP:0002591)2.08845505
104Absent speech (HP:0001344)2.06665026
105Hypomagnesemia (HP:0002917)2.06095028
106Bowel incontinence (HP:0002607)2.05396208
107Impaired vibratory sensation (HP:0002495)2.05322516
108Generalized myoclonic seizures (HP:0002123)2.04938975
109Amblyopia (HP:0000646)2.02539678
110Split foot (HP:0001839)2.02205758
111Urinary incontinence (HP:0000020)2.00709352
112Broad-based gait (HP:0002136)2.00555630
113Abnormality of saccadic eye movements (HP:0000570)1.98789308
114Rapidly progressive (HP:0003678)1.97648400
115Abnormality of ocular smooth pursuit (HP:0000617)1.97070540
116Anxiety (HP:0000739)1.93196389
117Progressive cerebellar ataxia (HP:0002073)1.93076608
118Partial agenesis of the corpus callosum (HP:0001338)1.92369521
119Dialeptic seizures (HP:0011146)1.92316274
120Diminished motivation (HP:0000745)1.92159922
121Foot dorsiflexor weakness (HP:0009027)1.92075316
122Hammertoe (HP:0001765)1.91806708
123Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.91619919
124Morphological abnormality of the pyramidal tract (HP:0002062)1.91483543
125Poor speech (HP:0002465)1.90531164
126Infantile muscular hypotonia (HP:0008947)1.90484108
127Hypokalemic alkalosis (HP:0001949)1.89926713
128Abnormal large intestine physiology (HP:0012700)1.89492421
129Abnormality of the lower motor neuron (HP:0002366)1.88700344
130Coronal craniosynostosis (HP:0004440)1.87643618
131Distal sensory impairment (HP:0002936)1.86709487
132Neuronal loss in central nervous system (HP:0002529)1.86687281
133Decreased motor nerve conduction velocity (HP:0003431)1.86495108
134Drooling (HP:0002307)1.83685910
135Paraparesis (HP:0002385)1.83661567
136Progressive inability to walk (HP:0002505)1.82949611
137Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.82619566
138Postural instability (HP:0002172)1.82382453
139Choreoathetosis (HP:0001266)1.82366624
140Methylmalonic acidemia (HP:0002912)1.81966381
141Abnormality of the septum pellucidum (HP:0007375)1.78707375
142Diminished movement (HP:0002374)1.75229116
143Relative macrocephaly (HP:0004482)1.75171435
144Hepatosplenomegaly (HP:0001433)1.74677880
145Cupped ear (HP:0000378)1.74439649
146Abnormality of the foot musculature (HP:0001436)1.73704753
147Absence seizures (HP:0002121)1.73601480
148Synostosis involving the elbow (HP:0003938)1.72993838
149Humeroradial synostosis (HP:0003041)1.72993838
150Impaired vibration sensation in the lower limbs (HP:0002166)1.72801187

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK395.68001438
2OXSR14.24845194
3EPHA42.83670748
4TNIK2.83322306
5CDK192.78035903
6EPHB12.71419838
7BCR2.60543198
8WNK42.37402199
9WNK12.33930707
10UHMK12.28052271
11PKN12.10293019
12NEK61.96433542
13PAK61.95617435
14MAPKAPK51.93564949
15PBK1.90481551
16MET1.89970790
17PRPF4B1.88882400
18NTRK11.84444497
19ICK1.83244205
20RIPK41.79209802
21LIMK11.71392923
22PLK21.71348199
23FGFR21.69104940
24CSNK1G31.68903808
25CSNK1A1L1.62951438
26PNCK1.62737379
27CAMK2B1.45614506
28CSNK1G21.43832694
29ROCK21.39774603
30MARK11.36494398
31MAP3K91.35334127
32KSR21.29334813
33FGR1.27620553
34TYRO31.24272350
35CSNK1G11.23809085
36ARAF1.20924823
37SGK21.19570944
38CLK11.19295377
39SGK2231.19156338
40SGK4941.19156338
41CAMK2D1.18033375
42CDK51.14555233
43NTRK31.14196613
44CAMKK21.07625407
45CDK141.05972218
46DAPK11.01749638
47TESK21.01158485
48SGK30.97371561
49CDK150.96273874
50CAMK2G0.95490004
51MAP3K130.94956233
52MARK20.92203013
53CDK180.90997936
54LATS20.90852457
55PAK30.90501031
56CDK11A0.87003676
57MINK10.86335057
58CAMK2A0.86127291
59PRKD30.85828131
60NTRK20.85572275
61RIPK10.84961393
62STK380.84527000
63PRKCQ0.82053306
64* MAPK100.81809122
65MAPK120.80653057
66MST40.79131662
67PDPK10.78171779
68CASK0.75421309
69RPS6KA30.74404095
70PINK10.72222419
71SIK20.71880445
72PRKD10.71743388
73PRKCH0.69100775
74PHKG20.68085378
75PHKG10.68085378
76STK110.66403860
77MAP3K20.66401782
78FES0.66304425
79FYN0.65530021
80TNK20.63362065
81MAP3K40.63350928
82CAMK40.61365623
83MUSK0.61198213
84MAP3K110.60723159
85PRKCZ0.60404395
86PRKCE0.57535751
87MAP2K40.55949848
88MAPK150.53711237
89KSR10.52416414
90DAPK20.51978040
91IRAK20.50616240
92PDK10.47109082
93MAPK130.46529436
94DYRK20.46191046
95CSNK1D0.45195406
96DAPK30.44998845
97BRSK10.44167957
98PRKCA0.42820976
99CSNK1A10.42188503
100PRKG10.41323867
101ERBB40.39738566
102PRKCG0.38354154
103BMX0.37999318
104GRK50.37084380
105PRKCB0.37020145
106ERBB20.36805503
107PRKACB0.36441735
108RET0.34271254
109CAMK1G0.33905320
110SGK10.31860983
111MAP2K70.31817816
112MAPK70.31660349
113PTK2B0.31508615
114DDR20.31079066
115ROCK10.28880299
116PAK10.28761260
117PRKACA0.28560164
118BMPR20.28298128
119MOS0.27930989
120DYRK1A0.27523415
121DMPK0.27399723
122CAMK10.27341713
123PDGFRB0.27317909
124CAMKK10.26797288
125ALK0.26524957

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009004.73699505
2Steroid biosynthesis_Homo sapiens_hsa001003.81615531
3Fatty acid elongation_Homo sapiens_hsa000623.53947383
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.07098694
5Ether lipid metabolism_Homo sapiens_hsa005652.64908444
6Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.21878991
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.21545420
8GABAergic synapse_Homo sapiens_hsa047272.11283860
9Glutamatergic synapse_Homo sapiens_hsa047241.97942177
10Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.97332299
11Axon guidance_Homo sapiens_hsa043601.88422310
12Morphine addiction_Homo sapiens_hsa050321.80664014
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.72998101
14Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.69920097
15Nicotine addiction_Homo sapiens_hsa050331.69004757
16Synaptic vesicle cycle_Homo sapiens_hsa047211.65450275
17Serotonergic synapse_Homo sapiens_hsa047261.57796053
18Nitrogen metabolism_Homo sapiens_hsa009101.57309435
19Oxidative phosphorylation_Homo sapiens_hsa001901.57006099
20Circadian entrainment_Homo sapiens_hsa047131.56104455
21Butanoate metabolism_Homo sapiens_hsa006501.51877186
22Long-term depression_Homo sapiens_hsa047301.41932022
23Vitamin B6 metabolism_Homo sapiens_hsa007501.40871932
24Sphingolipid metabolism_Homo sapiens_hsa006001.40364678
25Sulfur metabolism_Homo sapiens_hsa009201.39776123
26Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.35592091
27Cocaine addiction_Homo sapiens_hsa050301.30385149
28Olfactory transduction_Homo sapiens_hsa047401.28774676
29Dopaminergic synapse_Homo sapiens_hsa047281.26775033
30Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.24347337
31Bile secretion_Homo sapiens_hsa049761.23840625
32Salivary secretion_Homo sapiens_hsa049701.22642481
33Cholinergic synapse_Homo sapiens_hsa047251.17400000
34Parkinsons disease_Homo sapiens_hsa050121.17382884
35Collecting duct acid secretion_Homo sapiens_hsa049661.17138226
36Alzheimers disease_Homo sapiens_hsa050101.17074889
37beta-Alanine metabolism_Homo sapiens_hsa004101.15605265
38Estrogen signaling pathway_Homo sapiens_hsa049151.14739463
39Linoleic acid metabolism_Homo sapiens_hsa005911.13559697
40Renal cell carcinoma_Homo sapiens_hsa052111.11685622
41Amphetamine addiction_Homo sapiens_hsa050311.11570059
42Gastric acid secretion_Homo sapiens_hsa049711.07750236
43Long-term potentiation_Homo sapiens_hsa047201.07266835
44Protein export_Homo sapiens_hsa030601.04900876
45alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.03292914
46Vibrio cholerae infection_Homo sapiens_hsa051101.02352616
47SNARE interactions in vesicular transport_Homo sapiens_hsa041300.99751469
48Cardiac muscle contraction_Homo sapiens_hsa042600.99227162
49Phospholipase D signaling pathway_Homo sapiens_hsa040720.98457668
50Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.97846251
51cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95636788
52Endocytosis_Homo sapiens_hsa041440.93632618
53Thyroid hormone synthesis_Homo sapiens_hsa049180.92917267
54Sphingolipid signaling pathway_Homo sapiens_hsa040710.89699708
55Tight junction_Homo sapiens_hsa045300.89490316
56Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.87511147
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.86947939
58Glioma_Homo sapiens_hsa052140.85422475
59Rap1 signaling pathway_Homo sapiens_hsa040150.83830024
60Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.83284729
61Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.83121391
62Renin secretion_Homo sapiens_hsa049240.82709503
63ErbB signaling pathway_Homo sapiens_hsa040120.82405561
64Gap junction_Homo sapiens_hsa045400.80373974
65Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.80302301
66Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.80113618
67Histidine metabolism_Homo sapiens_hsa003400.79586875
68Ras signaling pathway_Homo sapiens_hsa040140.77106446
69Dorso-ventral axis formation_Homo sapiens_hsa043200.76801853
70Inositol phosphate metabolism_Homo sapiens_hsa005620.76691535
71Arginine and proline metabolism_Homo sapiens_hsa003300.75980148
72Taste transduction_Homo sapiens_hsa047420.74943805
73cAMP signaling pathway_Homo sapiens_hsa040240.73172768
74Ovarian steroidogenesis_Homo sapiens_hsa049130.72736513
75Glycerophospholipid metabolism_Homo sapiens_hsa005640.72317415
76Oxytocin signaling pathway_Homo sapiens_hsa049210.72134985
77Oocyte meiosis_Homo sapiens_hsa041140.71610253
78Phototransduction_Homo sapiens_hsa047440.71171710
79Pancreatic secretion_Homo sapiens_hsa049720.70645191
80Carbohydrate digestion and absorption_Homo sapiens_hsa049730.70171112
81Insulin secretion_Homo sapiens_hsa049110.69556898
82Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.67338338
83Calcium signaling pathway_Homo sapiens_hsa040200.67057855
84Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.65063709
85Rheumatoid arthritis_Homo sapiens_hsa053230.63123004
86Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60355242
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.59919717
88Type II diabetes mellitus_Homo sapiens_hsa049300.58585016
89Aldosterone synthesis and secretion_Homo sapiens_hsa049250.58120231
90Circadian rhythm_Homo sapiens_hsa047100.56862260
91GnRH signaling pathway_Homo sapiens_hsa049120.56120524
92Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.55457962
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.55032118
94Fatty acid metabolism_Homo sapiens_hsa012120.52464850
95Choline metabolism in cancer_Homo sapiens_hsa052310.52244662
96Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50641867
97ABC transporters_Homo sapiens_hsa020100.49285922
98Lysosome_Homo sapiens_hsa041420.49234117
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48933993
100Fatty acid biosynthesis_Homo sapiens_hsa000610.48107375
101Alcoholism_Homo sapiens_hsa050340.46838168
102Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46792631
103Huntingtons disease_Homo sapiens_hsa050160.46088798
104VEGF signaling pathway_Homo sapiens_hsa043700.44752457
105MAPK signaling pathway_Homo sapiens_hsa040100.43505508
106Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.43296344
107Regulation of actin cytoskeleton_Homo sapiens_hsa048100.43146997
108Mineral absorption_Homo sapiens_hsa049780.42951439
109Thyroid hormone signaling pathway_Homo sapiens_hsa049190.40935046
110Glucagon signaling pathway_Homo sapiens_hsa049220.40431799
111Dilated cardiomyopathy_Homo sapiens_hsa054140.40004050
112Melanogenesis_Homo sapiens_hsa049160.39498230
113Autoimmune thyroid disease_Homo sapiens_hsa053200.39083636
114Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.38776967
115Arginine biosynthesis_Homo sapiens_hsa002200.38720371
116Propanoate metabolism_Homo sapiens_hsa006400.36935632
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.35843508
118Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.35137108
119Glutathione metabolism_Homo sapiens_hsa004800.34783382
120Arachidonic acid metabolism_Homo sapiens_hsa005900.34039458
121Phagosome_Homo sapiens_hsa041450.33614863
122Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.33084045
123Chemokine signaling pathway_Homo sapiens_hsa040620.32944666
124Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.32097810
125Prion diseases_Homo sapiens_hsa050200.31547782
126Wnt signaling pathway_Homo sapiens_hsa043100.29135924
127Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.27314134
128Hippo signaling pathway_Homo sapiens_hsa043900.25283643

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