MON1B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sulfation (GO:0051923)3.97484229
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.59074902
3negative regulation of cell killing (GO:0031342)3.51262836
4negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.51262836
5antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.42761599
6presynaptic membrane assembly (GO:0097105)3.34270993
7antigen processing and presentation of endogenous antigen (GO:0019883)3.32076830
8regulation of interferon-beta biosynthetic process (GO:0045357)3.30755928
9ionotropic glutamate receptor signaling pathway (GO:0035235)3.22885159
10neuron cell-cell adhesion (GO:0007158)3.22640582
11positive regulation of gamma-delta T cell activation (GO:0046645)3.19144423
12interferon-gamma secretion (GO:0072643)3.14889749
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.12454625
14CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.11581145
15vocalization behavior (GO:0071625)3.09869204
16positive regulation of fatty acid oxidation (GO:0046321)3.08832803
17positive regulation of fatty acid beta-oxidation (GO:0032000)3.07452418
18modulation by virus of host process (GO:0019054)3.01699525
19positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.01175981
20regulation of gamma-delta T cell activation (GO:0046643)3.00167646
21positive regulation of histone deacetylation (GO:0031065)2.98059625
22response to type I interferon (GO:0034340)2.95501510
23negative regulation of synaptic transmission, GABAergic (GO:0032229)2.94398408
24cytoplasmic mRNA processing body assembly (GO:0033962)2.93207266
25response to peptidoglycan (GO:0032494)2.92136555
26glutamate receptor signaling pathway (GO:0007215)2.90784880
27gamma-aminobutyric acid signaling pathway (GO:0007214)2.90132188
28modulation by symbiont of host cellular process (GO:0044068)2.89440372
29modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.87339723
30positive regulation by organism of defense response of other organism involved in symbiotic interact2.87339723
31modulation by symbiont of host immune response (GO:0052553)2.87339723
32positive regulation by symbiont of host defense response (GO:0052509)2.87339723
33modulation by symbiont of host defense response (GO:0052031)2.87339723
34modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.87339723
35immunoglobulin mediated immune response (GO:0016064)2.84856014
36negative T cell selection (GO:0043383)2.84812519
37positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.84706612
38locomotory exploration behavior (GO:0035641)2.83292844
39positive regulation of CREB transcription factor activity (GO:0032793)2.82730725
40negative regulation of lymphocyte mediated immunity (GO:0002707)2.82711899
41cellular response to interleukin-15 (GO:0071350)2.82547228
42serotonin receptor signaling pathway (GO:0007210)2.82516107
43regulation of B cell receptor signaling pathway (GO:0050855)2.79096236
44positive regulation of mast cell activation (GO:0033005)2.78234299
45cellular response to type I interferon (GO:0071357)2.77633247
46type I interferon signaling pathway (GO:0060337)2.77633247
47negative thymic T cell selection (GO:0045060)2.76835225
48positive T cell selection (GO:0043368)2.74179678
49histone H3-K36 demethylation (GO:0070544)2.71185238
50regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.70975705
51regulation of glutamate receptor signaling pathway (GO:1900449)2.70915292
52L-amino acid import (GO:0043092)2.70782986
53germinal center formation (GO:0002467)2.70178814
54cerebellar Purkinje cell differentiation (GO:0021702)2.70146310
55mature B cell differentiation (GO:0002335)2.68749386
56presynaptic membrane organization (GO:0097090)2.67872597
57regulation of germinal center formation (GO:0002634)2.66472642
58regulation of memory T cell differentiation (GO:0043380)2.65030515
59regulation of regulatory T cell differentiation (GO:0045589)2.64981297
60regulation of platelet aggregation (GO:0090330)2.63869033
61regulation of short-term neuronal synaptic plasticity (GO:0048172)2.63865306
62leukocyte migration involved in inflammatory response (GO:0002523)2.63179695
63T cell selection (GO:0045058)2.62633663
64positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.61593330
65positive regulation of interferon-alpha production (GO:0032727)2.61268877
66positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.61187925
67response to interleukin-15 (GO:0070672)2.60769913
68tolerance induction (GO:0002507)2.59982221
69T cell migration (GO:0072678)2.59646637
70regulation of gamma-delta T cell differentiation (GO:0045586)2.59191398
71positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.59099756
72negative regulation of homotypic cell-cell adhesion (GO:0034111)2.58838927
73activated T cell proliferation (GO:0050798)2.58738714
74response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.58286835
75response to host immune response (GO:0052572)2.58286835
76detection of other organism (GO:0098543)2.57972065
77negative regulation of interleukin-12 production (GO:0032695)2.57910725
78regulation of mast cell activation (GO:0033003)2.55864142
79G-protein coupled receptor internalization (GO:0002031)2.54766699
80regulation of interferon-gamma biosynthetic process (GO:0045072)2.54503688
81startle response (GO:0001964)2.54015349
82cellular extravasation (GO:0045123)2.53179814
83mannose metabolic process (GO:0006013)2.52383210
84detection of bacterium (GO:0016045)2.51134058
85interferon-gamma-mediated signaling pathway (GO:0060333)2.51108560
86response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.50929456
87response to host (GO:0075136)2.50929456
88response to host defenses (GO:0052200)2.50929456
89synaptic transmission, glutamatergic (GO:0035249)2.49149093
90regulation of interferon-alpha production (GO:0032647)2.48828502
91neuron-neuron synaptic transmission (GO:0007270)2.46065707
92G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.45424120
93adaptation of signaling pathway (GO:0023058)2.45013754
94Golgi to endosome transport (GO:0006895)2.44752150
95negative regulation of systemic arterial blood pressure (GO:0003085)2.44629596
96glycosphingolipid biosynthetic process (GO:0006688)2.43476645
97DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.43453932
98regulation of Rap GTPase activity (GO:0032317)2.42883389
99import into cell (GO:0098657)2.41938981
100regulation of synaptic vesicle exocytosis (GO:2000300)2.41032299
101regulation of fatty acid beta-oxidation (GO:0031998)2.40061983
102detection of molecule of bacterial origin (GO:0032490)2.38485726
103neutrophil activation (GO:0042119)2.38065706
104myeloid cell activation involved in immune response (GO:0002275)2.38030454
105regulation of mast cell degranulation (GO:0043304)2.37978578
106detection of external biotic stimulus (GO:0098581)2.35854119
107negative regulation of leukocyte mediated immunity (GO:0002704)2.34953278
108negative regulation of protein oligomerization (GO:0032460)2.34743373
109negative regulation of T cell mediated immunity (GO:0002710)2.34713701
110long-term memory (GO:0007616)2.34398372
111histone H3-K4 trimethylation (GO:0080182)2.33798168
112long-term synaptic potentiation (GO:0060291)2.33770584
113regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.33603144
114thymic T cell selection (GO:0045061)2.33302859
115neuron recognition (GO:0008038)2.33228042
116positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.30643071
117microglial cell activation (GO:0001774)2.29622855
118B cell receptor signaling pathway (GO:0050853)2.29299613
119negative regulation of immunoglobulin mediated immune response (GO:0002890)2.28696730
120negative regulation of B cell mediated immunity (GO:0002713)2.28696730
121nerve growth factor signaling pathway (GO:0038180)2.28495433
122regulation of synaptic transmission, glutamatergic (GO:0051966)2.28219541
123regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.27077873
124positive thymic T cell selection (GO:0045059)2.26492740
125negative regulation of type 2 immune response (GO:0002829)2.25252896
126regulation of mast cell activation involved in immune response (GO:0033006)2.24699911
127neutrophil mediated immunity (GO:0002446)2.24616114
128positive regulation of toll-like receptor signaling pathway (GO:0034123)2.24508696
129response to protozoan (GO:0001562)2.24503566
130leukocyte aggregation (GO:0070486)2.24499397
131regulation of synaptic vesicle transport (GO:1902803)2.23803078
132CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.23612903
133T-helper cell differentiation (GO:0042093)2.23612903
134regulation of interferon-beta production (GO:0032648)2.23425344
135regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.23383833
136granulocyte activation (GO:0036230)2.22858304
137neuronal action potential propagation (GO:0019227)2.22685176
138G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.22681530
139macrophage activation involved in immune response (GO:0002281)2.22334102
140response to pheromone (GO:0019236)2.22057268
141regulation of dendritic cell antigen processing and presentation (GO:0002604)2.21904531
142positive regulation of protein deacetylation (GO:0090312)2.21854365
143JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.21812077
144positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.21388725
145negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.20315924
146regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.20261688
147regulation of homotypic cell-cell adhesion (GO:0034110)2.20195100
148NIK/NF-kappaB signaling (GO:0038061)2.20181398
149defense response to protozoan (GO:0042832)2.20118072
150cellular response to ATP (GO:0071318)2.20084913
151positive regulation of mast cell activation involved in immune response (GO:0033008)2.19590112
152negative regulation of exocytosis (GO:0045920)2.19557556
153negative regulation of neurotransmitter secretion (GO:0046929)2.19368815
154axonal fasciculation (GO:0007413)2.19136533
155cellular potassium ion homeostasis (GO:0030007)2.18869122
156cerebral cortex radially oriented cell migration (GO:0021799)2.18858686
157negative regulation of calcium ion transport into cytosol (GO:0010523)2.18233150
158positive regulation of antigen processing and presentation (GO:0002579)2.14233081
159protein localization to synapse (GO:0035418)2.13497140
160transmission of nerve impulse (GO:0019226)2.12671740
161synaptic vesicle endocytosis (GO:0048488)2.11964607
162opioid receptor signaling pathway (GO:0038003)2.11295550
163postsynaptic membrane organization (GO:0001941)2.10656557
164lens fiber cell differentiation (GO:0070306)2.10101038
165antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.09888811
166negative regulation of neurotransmitter transport (GO:0051589)2.09639922
167neutrophil activation involved in immune response (GO:0002283)2.08898440
168positive regulation of Rap GTPase activity (GO:0032854)2.07221756

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1STAT6_21828071_ChIP-Seq_BEAS2B_Human4.85928529
2EZH2_22144423_ChIP-Seq_EOC_Human4.08973250
3GBX2_23144817_ChIP-Seq_PC3_Human3.17048499
4VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.75741496
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.38383994
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.34487761
7SMAD_19615063_ChIP-ChIP_OVARY_Human2.34330778
8SCL_19346495_ChIP-Seq_HPC-7_Human2.27860894
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.16501736
10E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.13323274
11SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.10733584
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.98357890
13IKZF1_21737484_ChIP-ChIP_HCT116_Human1.95726278
14MYC_22102868_ChIP-Seq_BL_Human1.92447168
15ZFP57_27257070_Chip-Seq_ESCs_Mouse1.86310210
16SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.86249575
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.85854285
18KDM2B_26808549_Chip-Seq_SUP-B15_Human1.84878426
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.81829301
20DROSHA_22980978_ChIP-Seq_HELA_Human1.80051553
21* TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.79203931
22TAF15_26573619_Chip-Seq_HEK293_Human1.75267370
23AR_21572438_ChIP-Seq_LNCaP_Human1.72907901
24KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.72083006
25* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.71767480
26VDR_24763502_ChIP-Seq_THP-1_Human1.71555562
27TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.68918135
28PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.68069724
29SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.67279701
30* REST_21632747_ChIP-Seq_MESCs_Mouse1.66253299
31EZH2_18974828_ChIP-Seq_MESCs_Mouse1.65757801
32RNF2_18974828_ChIP-Seq_MESCs_Mouse1.65757801
33SPI1_23127762_ChIP-Seq_K562_Human1.64877841
34IGF1R_20145208_ChIP-Seq_DFB_Human1.64877127
35GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.64150947
36GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.62312635
37SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.61803210
38KDM2B_26808549_Chip-Seq_DND41_Human1.60413427
39RUNX_20019798_ChIP-Seq_JUKART_Human1.60121585
40SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.59991966
41GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.58554030
42ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.58490417
43RNF2_27304074_Chip-Seq_ESCs_Mouse1.57747587
44MTF2_20144788_ChIP-Seq_MESCs_Mouse1.57565151
45P300_19829295_ChIP-Seq_ESCs_Human1.55907215
46POU3F2_20337985_ChIP-ChIP_501MEL_Human1.55064297
47IRF8_21731497_ChIP-ChIP_J774_Mouse1.54326044
48JARID2_20075857_ChIP-Seq_MESCs_Mouse1.51450494
49ESR1_21235772_ChIP-Seq_MCF-7_Human1.51193564
50TCF7_22412390_ChIP-Seq_EML_Mouse1.49489072
51ESR2_21235772_ChIP-Seq_MCF-7_Human1.47688122
52SMAD4_21799915_ChIP-Seq_A2780_Human1.47263648
53VDR_21846776_ChIP-Seq_THP-1_Human1.46806074
54SUZ12_27294783_Chip-Seq_ESCs_Mouse1.43592657
55CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.42168777
56RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.41925606
57ZNF217_24962896_ChIP-Seq_MCF-7_Human1.41403008
58EZH2_27304074_Chip-Seq_ESCs_Mouse1.40864848
59STAT3_23295773_ChIP-Seq_U87_Human1.40486656
60IRF8_22096565_ChIP-ChIP_GC-B_Human1.40403052
61ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.39791531
62EZH2_27294783_Chip-Seq_ESCs_Mouse1.39259692
63SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.38540504
64STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.38530634
65TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.37024425
66EED_16625203_ChIP-ChIP_MESCs_Mouse1.35289032
67MAF_26560356_Chip-Seq_TH1_Human1.35185133
68GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.35129523
69NANOG_18555785_Chip-Seq_ESCs_Mouse1.34655270
70IRF8_27001747_Chip-Seq_BMDM_Mouse1.34063893
71UTX_26944678_Chip-Seq_JUKART_Human1.32840866
72GATA1_19941827_ChIP-Seq_MEL_Mouse1.32181525
73KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.28528447
74GATA3_27048872_Chip-Seq_THYMUS_Human1.27646116
75PCGF2_27294783_Chip-Seq_ESCs_Mouse1.25708656
76SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.24450681
77* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23739849
78RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.23265129
79CTBP2_25329375_ChIP-Seq_LNCAP_Human1.22931141
80MYB_26560356_Chip-Seq_TH2_Human1.21902995
81VDR_24787735_ChIP-Seq_THP-1_Human1.21279135
82* POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.21082295
83* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21082295
84FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.20704935
85TCF4_23295773_ChIP-Seq_U87_Human1.20460309
86CTBP1_25329375_ChIP-Seq_LNCAP_Human1.20046627
87AHR_22903824_ChIP-Seq_MCF-7_Human1.19322646
88FLI1_27457419_Chip-Seq_LIVER_Mouse1.19318880
89SUZ12_18555785_Chip-Seq_ESCs_Mouse1.18763308
90AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.18711971
91ARNT_22903824_ChIP-Seq_MCF-7_Human1.18514729
92ER_23166858_ChIP-Seq_MCF-7_Human1.16920769
93SUZ12_27294783_Chip-Seq_NPCs_Mouse1.16842765
94MYB_26560356_Chip-Seq_TH1_Human1.16701833
95E2F1_18555785_Chip-Seq_ESCs_Mouse1.16530293
96CBX2_27304074_Chip-Seq_ESCs_Mouse1.15582471
97EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.15545528
98RARB_27405468_Chip-Seq_BRAIN_Mouse1.15179109
99P53_22387025_ChIP-Seq_ESCs_Mouse1.14305355
100CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14056331
101Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.13501555
102CMYC_18555785_Chip-Seq_ESCs_Mouse1.13179503
103IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.13039647
104BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12463445
105KDM2B_26808549_Chip-Seq_JURKAT_Human1.11687636
106PIAS1_25552417_ChIP-Seq_VCAP_Human1.11576793
107P53_22127205_ChIP-Seq_FIBROBLAST_Human1.11058035
108NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.10805591
109PRDM14_20953172_ChIP-Seq_ESCs_Human1.10632164
110AR_25329375_ChIP-Seq_VCAP_Human1.10377518
111BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.10349806
112NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.10185402
113AR_19668381_ChIP-Seq_PC3_Human1.09962223
114LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.09634163
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06540174
116BP1_19119308_ChIP-ChIP_Hs578T_Human1.06196879
117TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.05820583
118STAT4_19710469_ChIP-ChIP_TH1__Mouse1.05291466
119GATA1_19941826_ChIP-Seq_K562_Human1.04961092
120MAF_26560356_Chip-Seq_TH2_Human1.04817060
121* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.04271102
122NFE2_27457419_Chip-Seq_LIVER_Mouse1.04184318
123NMYC_18555785_Chip-Seq_ESCs_Mouse1.04120340
124* SMAD3_21741376_ChIP-Seq_EPCs_Human1.03873171
125TP53_16413492_ChIP-PET_HCT116_Human1.03379549
126REST_18959480_ChIP-ChIP_MESCs_Mouse1.02900955
127KDM2B_26808549_Chip-Seq_K562_Human1.02618022
128* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.01988268
129PCGF2_27294783_Chip-Seq_NPCs_Mouse1.01779761
130RUNX1_27514584_Chip-Seq_MCF-7_Human1.01187295
131NR3C1_21868756_ChIP-Seq_MCF10A_Human1.00996583
132RNF2_27304074_Chip-Seq_NSC_Mouse1.00331415
133EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.00328442
134RXR_22108803_ChIP-Seq_LS180_Human0.99996043
135RUNX1_22412390_ChIP-Seq_EML_Mouse0.99766524
136* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.99461251
137EZH2_27294783_Chip-Seq_NPCs_Mouse0.99427231
138* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99194177
139EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.98820338
140SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.98784599
141* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.97611963
142FOXA2_19822575_ChIP-Seq_HepG2_Human0.97346001
143GATA2_19941826_ChIP-Seq_K562_Human0.96294201
144MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.96059243
145SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.95962181
146GATA3_26560356_Chip-Seq_TH2_Human0.95821913
147GATA2_21666600_ChIP-Seq_HMVEC_Human0.92820239
148SMRT_27268052_Chip-Seq_Bcells_Human0.92134963
149LXR_22292898_ChIP-Seq_THP-1_Human0.91098963
150MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.90944517
151FOXO3_23340844_ChIP-Seq_DLD1_Human0.87942322
152CREB1_26743006_Chip-Seq_LNCaP_Human0.87407680
153* SPI1_23547873_ChIP-Seq_NB4_Human0.86320274
154PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.85217743
155CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.83067688
156BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.82465470
157ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.81783286
158CTNNB1_20460455_ChIP-Seq_HCT116_Human0.81169519
159NOTCH1_21737748_ChIP-Seq_TLL_Human0.80850847
160MYB_21317192_ChIP-Seq_ERMYB_Mouse0.80725940
161PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.80366471
162CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.79325756
163* TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.78655223
164* LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.78375412
165NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.77772168
166WT1_25993318_ChIP-Seq_PODOCYTE_Human0.76255207
167ESR1_20079471_ChIP-ChIP_T-47D_Human0.75790013

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.61644658
2MP0002735_abnormal_chemical_nociception3.26741583
3MP0003880_abnormal_central_pattern2.98557957
4MP0002138_abnormal_hepatobiliary_system2.94112192
5MP0003724_increased_susceptibility_to2.82580412
6MP0003635_abnormal_synaptic_transmissio2.35889976
7MP0005387_immune_system_phenotype2.33143960
8MP0001790_abnormal_immune_system2.33143960
9MP0005310_abnormal_salivary_gland2.29987326
10MP0001968_abnormal_touch/_nociception2.28245668
11MP0009745_abnormal_behavioral_response2.11026627
12MP0003787_abnormal_imprinting2.10245648
13MP0001501_abnormal_sleep_pattern2.04930375
14MP0002063_abnormal_learning/memory/cond2.02621497
15MP0002736_abnormal_nociception_after2.01494677
16MP0010386_abnormal_urinary_bladder2.00033888
17MP0002064_seizures1.99016481
18MP0004270_analgesia1.97926627
19MP0004510_myositis1.96787587
20MP0004043_abnormal_pH_regulation1.96246215
21MP0001486_abnormal_startle_reflex1.96098996
22MP0002572_abnormal_emotion/affect_behav1.86979407
23MP0005645_abnormal_hypothalamus_physiol1.86713652
24MP0003183_abnormal_peptide_metabolism1.86028945
25MP0005423_abnormal_somatic_nervous1.85602198
26MP0005671_abnormal_response_to1.78961797
27MP0001346_abnormal_lacrimal_gland1.77919466
28MP0001835_abnormal_antigen_presentation1.77418819
29MP0009046_muscle_twitch1.76241448
30MP0005167_abnormal_blood-brain_barrier1.75063933
31MP0005409_darkened_coat_color1.74855913
32MP0002163_abnormal_gland_morphology1.73983954
33MP0001800_abnormal_humoral_immune1.73167129
34MP0001986_abnormal_taste_sensitivity1.71970233
35MP0004947_skin_inflammation1.67679532
36MP0001529_abnormal_vocalization1.67312995
37MP0000569_abnormal_digit_pigmentation1.66797773
38MP0004742_abnormal_vestibular_system1.64695125
39MP0000685_abnormal_immune_system1.64234226
40MP0005000_abnormal_immune_tolerance1.61905317
41MP0002272_abnormal_nervous_system1.61136956
42MP0002734_abnormal_mechanical_nocicepti1.59267202
43MP0008872_abnormal_physiological_respon1.57089231
44MP0002067_abnormal_sensory_capabilities1.55304820
45MP0010155_abnormal_intestine_physiology1.53437281
46MP0002452_abnormal_antigen_presenting1.49748372
47MP0005379_endocrine/exocrine_gland_phen1.44973058
48MP0004858_abnormal_nervous_system1.43912594
49MP0003303_peritoneal_inflammation1.43683135
50MP0002723_abnormal_immune_serum1.43151690
51MP0002420_abnormal_adaptive_immunity1.42894026
52MP0002419_abnormal_innate_immunity1.42623267
53MP0004883_abnormal_blood_vessel1.41913488
54MP0001819_abnormal_immune_cell1.41722638
55MP0002928_abnormal_bile_duct1.41397880
56MP0002277_abnormal_respiratory_mucosa1.41148563
57MP0001502_abnormal_circadian_rhythm1.40955742
58MP0002089_abnormal_postnatal_growth/wei1.40257372
59MP0001970_abnormal_pain_threshold1.39961117
60MP0000778_abnormal_nervous_system1.37837080
61MP0001845_abnormal_inflammatory_respons1.37141768
62MP0001533_abnormal_skeleton_physiology1.36762929
63MP0008569_lethality_at_weaning1.35863759
64MP0003300_gastrointestinal_ulcer1.35733851
65MP0000566_synostosis1.31782981
66MP0001485_abnormal_pinna_reflex1.28392312
67MP0002653_abnormal_ependyma_morphology1.27133126
68MP0004381_abnormal_hair_follicle1.25773612
69MP0002733_abnormal_thermal_nociception1.25657366
70MP0000689_abnormal_spleen_morphology1.25456345
71MP0002557_abnormal_social/conspecific_i1.23996618
72MP0003172_abnormal_lysosome_physiology1.23423355
73MP0000920_abnormal_myelination1.20555842
74MP0002148_abnormal_hypersensitivity_rea1.19278072
75MP0005646_abnormal_pituitary_gland1.19009067
76MP0001873_stomach_inflammation1.18760636
77MP0002139_abnormal_hepatobiliary_system1.18352332
78MP0001984_abnormal_olfaction1.18097823
79MP0001440_abnormal_grooming_behavior1.15531588
80MP0002398_abnormal_bone_marrow1.14405636
81MP0001851_eye_inflammation1.13654902
82MP0005025_abnormal_response_to1.13269601
83MP0005076_abnormal_cell_differentiation1.12562224
84MP0002184_abnormal_innervation1.12451932
85MP0002102_abnormal_ear_morphology1.12445561
86MP0004924_abnormal_behavior1.11575915
87MP0005386_behavior/neurological_phenoty1.11575915
88MP0008260_abnormal_autophagy1.11318112
89MP0000716_abnormal_immune_system1.10618728
90MP0008961_abnormal_basal_metabolism1.10194749
91MP0003763_abnormal_thymus_physiology1.09402944
92MP0009764_decreased_sensitivity_to1.09240871
93MP0000015_abnormal_ear_pigmentation1.08163238
94MP0001188_hyperpigmentation1.07996268
95MP0003136_yellow_coat_color1.07218045
96MP0009785_altered_susceptibility_to1.06529676
97MP0002429_abnormal_blood_cell1.04126055
98MP0003436_decreased_susceptibility_to1.03763307
99MP0009278_abnormal_bone_marrow1.03610924
100MP0000703_abnormal_thymus_morphology1.02696021
101MP0005174_abnormal_tail_pigmentation1.02390983
102MP0002132_abnormal_respiratory_system1.02383217
103MP0004134_abnormal_chest_morphology1.01674728
104MP0001663_abnormal_digestive_system1.01214287
105MP0002722_abnormal_immune_system0.99320784
106MP0006292_abnormal_olfactory_placode0.97190081
107MP0000371_diluted_coat_color0.96332883
108MP0008469_abnormal_protein_level0.95498609
109MP0003690_abnormal_glial_cell0.95488986
110MP0001765_abnormal_ion_homeostasis0.95212231
111MP0000631_abnormal_neuroendocrine_gland0.94166944
112MP0003091_abnormal_cell_migration0.93681583
113MP0003329_amyloid_beta_deposits0.92353291
114MP0004142_abnormal_muscle_tone0.91641761
115MP0005058_abnormal_lysosome_morphology0.89950671
116MP0009840_abnormal_foam_cell0.87646921
117MP0006082_CNS_inflammation0.87573206
118MP0001963_abnormal_hearing_physiology0.83941380
119MP0002066_abnormal_motor_capabilities/c0.83122334
120MP0006276_abnormal_autonomic_nervous0.81753585
121MP0005164_abnormal_response_to0.81566065
122MP0003045_fibrosis0.81516787
123MP0002405_respiratory_system_inflammati0.80074040
124MP0009333_abnormal_splenocyte_physiolog0.80072950
125MP0004885_abnormal_endolymph0.80053208
126MP0002882_abnormal_neuron_morphology0.79549701
127MP0005166_decreased_susceptibility_to0.79518775
128MP0005464_abnormal_platelet_physiology0.79467903
129MP0002822_catalepsy0.79002674
130MP0002998_abnormal_bone_remodeling0.78931272
131MP0000470_abnormal_stomach_morphology0.77411476
132MP0005451_abnormal_body_composition0.76324069
133MP0003866_abnormal_defecation0.76205801
134MP0000678_abnormal_parathyroid_gland0.75250884
135MP0005085_abnormal_gallbladder_physiolo0.75107016
136MP0003075_altered_response_to0.74462647
137MP0005670_abnormal_white_adipose0.74138663
138MP0003633_abnormal_nervous_system0.73812337
139MP0009115_abnormal_fat_cell0.73754768
140MP0000383_abnormal_hair_follicle0.73659820
141MP0002009_preneoplasia0.73571608
142MP0002693_abnormal_pancreas_physiology0.73557774
143MP0001919_abnormal_reproductive_system0.71647191
144MP0005448_abnormal_energy_balance0.67989393
145MP0005381_digestive/alimentary_phenotyp0.66650183
146MP0001664_abnormal_digestion0.64351189
147MP0002136_abnormal_kidney_physiology0.61978699

Predicted human phenotypes

RankGene SetZ-score
1Abnormal delayed hypersensitivity skin test (HP:0002963)3.88546245
2Febrile seizures (HP:0002373)3.83336039
3Obstructive sleep apnea (HP:0002870)3.82906244
4Focal motor seizures (HP:0011153)3.77074475
5Chronic otitis media (HP:0000389)3.63670425
6Retrobulbar optic neuritis (HP:0100654)3.29248385
7Optic neuritis (HP:0100653)3.29248385
8Atonic seizures (HP:0010819)3.17626761
9Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.98200290
10Chronic mucocutaneous candidiasis (HP:0002728)2.98190578
11Recurrent cutaneous fungal infections (HP:0011370)2.98190578
12Recurrent abscess formation (HP:0002722)2.97848201
13Agammaglobulinemia (HP:0004432)2.94181143
14Myositis (HP:0100614)2.92506825
15Recurrent fungal infections (HP:0002841)2.83237342
16Mucopolysacchariduria (HP:0008155)2.78428132
17Urinary glycosaminoglycan excretion (HP:0003541)2.78428132
18Eczematoid dermatitis (HP:0000976)2.75205503
19Abnormality of macrophages (HP:0004311)2.74946246
20Epileptic encephalopathy (HP:0200134)2.73872366
21Panhypogammaglobulinemia (HP:0003139)2.73577723
22Supranuclear gaze palsy (HP:0000605)2.71994328
23Orchitis (HP:0100796)2.69175731
24Abnormality of mucopolysaccharide metabolism (HP:0011020)2.65999006
25Abnormality of polysaccharide metabolism (HP:0011012)2.65999006
26Abnormality of glycosaminoglycan metabolism (HP:0004371)2.65999006
27Focal seizures (HP:0007359)2.65342496
28Meningitis (HP:0001287)2.61630129
29Severe visual impairment (HP:0001141)2.60405271
30Recurrent bacterial skin infections (HP:0005406)2.59581577
31Dysostosis multiplex (HP:0000943)2.58279682
32Hemiplegia (HP:0002301)2.54462286
33Stomach cancer (HP:0012126)2.54236247
34Abnormality of the fingertips (HP:0001211)2.51521628
35Congenital sensorineural hearing impairment (HP:0008527)2.50574587
36Abnormality of T cell number (HP:0011839)2.50048272
37Recurrent viral infections (HP:0004429)2.49504444
38Chronic obstructive pulmonary disease (HP:0006510)2.48788064
39Obstructive lung disease (HP:0006536)2.48788064
40Abnormal hair whorl (HP:0010721)2.47264711
41Chronic sinusitis (HP:0011109)2.45593612
42Vasculitis (HP:0002633)2.41181053
43Pancreatic cysts (HP:0001737)2.40830791
44Abnormality of binocular vision (HP:0011514)2.38137165
45Diplopia (HP:0000651)2.38137165
46Increased neuronal autofluorescent lipopigment (HP:0002074)2.36660088
47T lymphocytopenia (HP:0005403)2.35884516
48Progressive cerebellar ataxia (HP:0002073)2.30134780
49Drooling (HP:0002307)2.29158486
50Excessive salivation (HP:0003781)2.29158486
51Increased cerebral lipofuscin (HP:0011813)2.27679305
52Slow saccadic eye movements (HP:0000514)2.26915889
53Conjunctival hamartoma (HP:0100780)2.21469266
54Absence seizures (HP:0002121)2.21285995
55Encephalitis (HP:0002383)2.19621876
56Thyroiditis (HP:0100646)2.17158403
57Recurrent skin infections (HP:0001581)2.14630089
58Decreased central vision (HP:0007663)2.12831523
59Dialeptic seizures (HP:0011146)2.11358279
60Elevated erythrocyte sedimentation rate (HP:0003565)2.10649556
61Broad-based gait (HP:0002136)2.10500862
62Hypochromic anemia (HP:0001931)2.09712932
63Widely spaced teeth (HP:0000687)2.09639073
64Pendular nystagmus (HP:0012043)2.09613083
65Hyperventilation (HP:0002883)2.08797342
66Abnormality of salivation (HP:0100755)2.08492469
67Absent speech (HP:0001344)2.08143926
68Generalized tonic-clonic seizures (HP:0002069)2.07874086
69Mediastinal lymphadenopathy (HP:0100721)2.07572865
70Pulmonary infiltrates (HP:0002113)2.06781937
71Hamartoma of the eye (HP:0010568)2.05546277
72Recurrent gram-negative bacterial infections (HP:0005420)2.05472094
73True hermaphroditism (HP:0010459)2.04946830
74Hemoptysis (HP:0002105)2.04176147
75Cellulitis (HP:0100658)2.03978952
76Absent rod-and cone-mediated responses on ERG (HP:0007688)1.98664654
77Increased IgE level (HP:0003212)1.98385986
78Porencephaly (HP:0002132)1.96619283
79Agitation (HP:0000713)1.95688706
80Sparse lateral eyebrow (HP:0005338)1.95349215
81Keratoconjunctivitis sicca (HP:0001097)1.93692261
82Inflammation of the large intestine (HP:0002037)1.93512122
83Recurrent pneumonia (HP:0006532)1.91622501
84Clumsiness (HP:0002312)1.90492685
85Autoimmune thrombocytopenia (HP:0001973)1.89924843
86Amelogenesis imperfecta (HP:0000705)1.89917548
87Abnormality of the columella (HP:0009929)1.89158938
88Colitis (HP:0002583)1.89150783
89Urinary bladder sphincter dysfunction (HP:0002839)1.89128193
90Verrucae (HP:0200043)1.88702177
91Papilloma (HP:0012740)1.88702177
92Abnormality of the sella turcica (HP:0002679)1.88034524
93Gastrointestinal stroma tumor (HP:0100723)1.88021109
94Protruding tongue (HP:0010808)1.87906025
95Recurrent sinusitis (HP:0011108)1.86565501
96Pancreatic fibrosis (HP:0100732)1.86021730
97Arterial tortuosity (HP:0005116)1.85158847
98Eosinophilia (HP:0001880)1.83536599
99Bone cyst (HP:0012062)1.83427159
100Abolished electroretinogram (ERG) (HP:0000550)1.82716278
101Genetic anticipation (HP:0003743)1.81733194
102Decreased circulating renin level (HP:0003351)1.81036239
103Asplenia (HP:0001746)1.80812246
104Gingivitis (HP:0000230)1.80380588
105Cystic liver disease (HP:0006706)1.80015944
106Keratoconjunctivitis (HP:0001096)1.79910549
107Furrowed tongue (HP:0000221)1.79369741
108Chronic diarrhea (HP:0002028)1.79003080
109Abnormality of the odontoid process (HP:0003310)1.78387202
110Curly hair (HP:0002212)1.77465245
111Thoracic kyphosis (HP:0002942)1.77292665
112Confusion (HP:0001289)1.77243267
113Increased corneal curvature (HP:0100692)1.76944655
114Keratoconus (HP:0000563)1.76944655
115Ureteral obstruction (HP:0006000)1.76580873
116Thickened helices (HP:0000391)1.76335227
117Neurofibrillary tangles (HP:0002185)1.76181499
118Aqueductal stenosis (HP:0002410)1.75736393
119Sleep apnea (HP:0010535)1.75338190
120Abnormality of glycolipid metabolism (HP:0010969)1.74517739
121Abnormality of liposaccharide metabolism (HP:0010968)1.74517739
122Abnormality of glycosphingolipid metabolism (HP:0004343)1.74517739
123Prostate neoplasm (HP:0100787)1.73684512
124Spontaneous hematomas (HP:0007420)1.73162519
125Gaze-evoked nystagmus (HP:0000640)1.73092851
126Abnormality of the right ventricle (HP:0001707)1.72851600
127Increased IgM level (HP:0003496)1.71959833
128Aplasia/Hypoplasia of the spleen (HP:0010451)1.71669185
129Restrictive lung disease (HP:0002091)1.71538930
130Lymphopenia (HP:0001888)1.70983617
131Ureteral stenosis (HP:0000071)1.70800986
132Pustule (HP:0200039)1.70747186
133Abnormality of eosinophils (HP:0001879)1.70641630
134Tented upper lip vermilion (HP:0010804)1.70120755
135Goiter (HP:0000853)1.69903979
136Hypoplasia of the odontoid process (HP:0003311)1.68497284
137Stereotypic behavior (HP:0000733)1.68374038
138Gastrointestinal inflammation (HP:0004386)1.67397806
139Xerostomia (HP:0000217)1.67160437
140Truncal ataxia (HP:0002078)1.66080349
141Vascular tortuosity (HP:0004948)1.66053075
142Postural instability (HP:0002172)1.64949655
143Generalized hypopigmentation of hair (HP:0011358)1.61726967
144Abnormality of cells of the lymphoid lineage (HP:0012140)1.60936525
145Recurrent lower respiratory tract infections (HP:0002783)1.60386393
146Leukocytosis (HP:0001974)1.59999794
147Recurrent bronchitis (HP:0002837)1.58629948
148Osteomyelitis (HP:0002754)1.54922865
149Inappropriate behavior (HP:0000719)1.54733281
150Basal ganglia calcification (HP:0002135)1.54229912
151Lip pit (HP:0100267)1.53898424
152Open mouth (HP:0000194)1.53828313
153Cheilitis (HP:0100825)1.53778529
154Stomatitis (HP:0010280)1.53633947
155Onion bulb formation (HP:0003383)1.53015051
156Interstitial pulmonary disease (HP:0006530)1.52957908
157Hip dysplasia (HP:0001385)1.52844657

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK42.90027498
2NTRK32.76948185
3MAP3K142.75000841
4SIK22.71759871
5TNIK2.71211701
6MAP3K132.67280830
7CASK2.53272697
8SIK32.48193881
9PRPF4B2.31884342
10BLK2.12514232
11NTRK21.97296277
12MAP3K91.95489776
13MAP2K71.95309551
14ERN11.92836813
15EPHA41.90741873
16TRIB31.88720010
17IRAK11.76951626
18MAP4K11.70424586
19FES1.70270854
20JAK31.66917844
21TXK1.59445331
22MKNK21.55318520
23WNK41.53982386
24MAP3K31.44724796
25BMPR1B1.37365611
26MAP3K41.36066780
27CLK11.35941160
28AKT31.35866339
29MAP3K21.35637137
30JAK11.35094891
31MAPK131.31440680
32YES11.31249051
33CSK1.30435301
34MAP3K101.28445747
35BMPR21.27915685
36INSRR1.27506305
37SMG11.27320521
38EPHA31.26002259
39FGFR41.22991747
40IRAK31.22331163
41SGK21.19952268
42SGK31.19183390
43SIK11.17389179
44DMPK1.16041016
45PRKCH1.14484786
46MARK31.11494842
47TNK21.10407303
48TAOK31.09449628
49CAMK1G1.08525328
50STK111.06770119
51MAPKAPK31.06121156
52IRAK41.03032911
53HCK1.02145767
54MARK21.02036640
55SYK1.01754394
56DAPK21.01532260
57KSR11.01461291
58SGK4940.99847285
59SGK2230.99847285
60EPHB10.97445316
61PRKCQ0.96597977
62STK390.94650078
63PLK20.93082528
64TAOK10.92977162
65FGR0.92550804
66IRAK20.91437510
67PAK60.91409347
68NTRK10.89850438
69CDK50.86988294
70CDK80.86352707
71EEF2K0.86026225
72SGK10.85564644
73STK100.84042231
74MAP3K110.84011745
75WNK10.83792071
76STK380.83611853
77ADRBK20.83383968
78FGFR30.81810605
79PRKCZ0.80653496
80CAMKK10.80472299
81PKN10.77830699
82CDK90.74390896
83IKBKE0.73704943
84CDK30.69983482
85LCK0.69008869
86NEK90.68087441
87GRK10.68055862
88PRKD20.67150730
89MAP3K70.66916908
90MARK10.66553344
91GRK60.65806537
92RPS6KA20.65113844
93CAMKK20.64423613
94RPS6KA60.61899450
95CAMK40.61185627
96IKBKB0.60180702
97STK240.60014344
98TYK20.59938817
99MAPK120.59077669
100CAMK1D0.59070572
101LMTK20.58482572
102PAK30.57855284
103KSR20.57655984
104EIF2AK20.57177616
105ACVR1B0.56811081
106TEC0.55423029
107GRK70.54966425
108PRKD30.54640772
109TAF10.54509925
110MAP2K40.54182340
111MELK0.53856504
112PRKCE0.53716851
113BRD40.53292087
114CSF1R0.53052902
115MAP3K60.52850646
116MAPKAPK20.51925060
117RPS6KC10.51535752
118RPS6KL10.51535752
119CHUK0.50746685
120ZAP700.49671540
121PTK60.49629400
122BTK0.49390725
123HIPK20.49077209
124CAMK10.49074415
125ALK0.49072916
126PNCK0.48929288
127NLK0.48242448
128DYRK20.47449519
129LYN0.47444585
130ITK0.47312599
131CDC42BPA0.46702532
132FYN0.46127938
133MAP3K10.44139130
134CDK120.42818571
135MAPK100.42595147
136DYRK1A0.40823309
137TBK10.40812604
138RAF10.40254838
139LATS10.39635297
140MAP2K60.39528304
141FRK0.37924452
142ABL10.37573944
143BCR0.37239069
144STK30.34646537

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.28583451
2Staphylococcus aureus infection_Homo sapiens_hsa051501.92991273
3Morphine addiction_Homo sapiens_hsa050321.73238612
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.69698695
5Taste transduction_Homo sapiens_hsa047421.61553255
6Glutamatergic synapse_Homo sapiens_hsa047241.59574029
7Asthma_Homo sapiens_hsa053101.58962437
8Primary immunodeficiency_Homo sapiens_hsa053401.54283361
9Olfactory transduction_Homo sapiens_hsa047401.48254592
10Long-term potentiation_Homo sapiens_hsa047201.46623383
11Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.43115167
12B cell receptor signaling pathway_Homo sapiens_hsa046621.36634841
13Serotonergic synapse_Homo sapiens_hsa047261.36567660
14Salivary secretion_Homo sapiens_hsa049701.34716360
15GABAergic synapse_Homo sapiens_hsa047271.33523699
16Circadian entrainment_Homo sapiens_hsa047131.33079537
17Synaptic vesicle cycle_Homo sapiens_hsa047211.30028433
18Graft-versus-host disease_Homo sapiens_hsa053321.29385285
19Osteoclast differentiation_Homo sapiens_hsa043801.27726782
20Phosphatidylinositol signaling system_Homo sapiens_hsa040701.27256804
21Autoimmune thyroid disease_Homo sapiens_hsa053201.25353930
22Intestinal immune network for IgA production_Homo sapiens_hsa046721.25270255
23Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.24938668
24T cell receptor signaling pathway_Homo sapiens_hsa046601.23657936
25Chemokine signaling pathway_Homo sapiens_hsa040621.23602396
26Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.21224555
27Leishmaniasis_Homo sapiens_hsa051401.20403327
28NF-kappa B signaling pathway_Homo sapiens_hsa040641.18788250
29Acute myeloid leukemia_Homo sapiens_hsa052211.16694495
30Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.14620751
31Notch signaling pathway_Homo sapiens_hsa043301.13703150
32Long-term depression_Homo sapiens_hsa047301.13561442
33Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.11874405
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.11677659
35Hepatitis C_Homo sapiens_hsa051601.11279405
36Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.10980643
37Insulin secretion_Homo sapiens_hsa049111.09990168
38Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.09627421
39Renin secretion_Homo sapiens_hsa049241.09401813
40Allograft rejection_Homo sapiens_hsa053301.08925056
41Tuberculosis_Homo sapiens_hsa051521.08903245
42Dopaminergic synapse_Homo sapiens_hsa047281.08085417
43Cholinergic synapse_Homo sapiens_hsa047251.06352470
44Toll-like receptor signaling pathway_Homo sapiens_hsa046201.05911292
45ABC transporters_Homo sapiens_hsa020101.05159482
46cAMP signaling pathway_Homo sapiens_hsa040241.02792469
47Amphetamine addiction_Homo sapiens_hsa050311.02010860
48Antigen processing and presentation_Homo sapiens_hsa046121.01614570
49Pancreatic cancer_Homo sapiens_hsa052121.01177464
50Neurotrophin signaling pathway_Homo sapiens_hsa047221.00480999
51Type II diabetes mellitus_Homo sapiens_hsa049301.00376640
52Herpes simplex infection_Homo sapiens_hsa051680.99977333
53Measles_Homo sapiens_hsa051620.99041027
54Type I diabetes mellitus_Homo sapiens_hsa049400.98709608
55Aldosterone synthesis and secretion_Homo sapiens_hsa049250.98260371
56Adipocytokine signaling pathway_Homo sapiens_hsa049200.95889017
57ErbB signaling pathway_Homo sapiens_hsa040120.95669713
58Choline metabolism in cancer_Homo sapiens_hsa052310.95247575
59Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.94438367
60MAPK signaling pathway_Homo sapiens_hsa040100.93305960
61NOD-like receptor signaling pathway_Homo sapiens_hsa046210.92182505
62Hematopoietic cell lineage_Homo sapiens_hsa046400.92106104
63Calcium signaling pathway_Homo sapiens_hsa040200.91815858
64Axon guidance_Homo sapiens_hsa043600.91500993
65Phospholipase D signaling pathway_Homo sapiens_hsa040720.91228339
66Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.89774438
67Maturity onset diabetes of the young_Homo sapiens_hsa049500.89537937
68Rheumatoid arthritis_Homo sapiens_hsa053230.88941535
69Gastric acid secretion_Homo sapiens_hsa049710.88518395
70Mineral absorption_Homo sapiens_hsa049780.88407569
71Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.88341197
72mTOR signaling pathway_Homo sapiens_hsa041500.88055971
73Oxytocin signaling pathway_Homo sapiens_hsa049210.87709536
74Dorso-ventral axis formation_Homo sapiens_hsa043200.86418070
75Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.86143569
76Glioma_Homo sapiens_hsa052140.84999374
77Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.84969358
78Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.84668648
79Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.83250089
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.82576561
81Prostate cancer_Homo sapiens_hsa052150.82376536
82Cocaine addiction_Homo sapiens_hsa050300.82373212
83Insulin resistance_Homo sapiens_hsa049310.81428213
84FoxO signaling pathway_Homo sapiens_hsa040680.81310852
85TNF signaling pathway_Homo sapiens_hsa046680.80864520
86GnRH signaling pathway_Homo sapiens_hsa049120.80276936
87Pancreatic secretion_Homo sapiens_hsa049720.79829537
88RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.79214178
89Lysosome_Homo sapiens_hsa041420.79118118
90Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.78763243
91Vitamin digestion and absorption_Homo sapiens_hsa049770.76264037
92Phototransduction_Homo sapiens_hsa047440.75724252
93Inositol phosphate metabolism_Homo sapiens_hsa005620.75132485
94African trypanosomiasis_Homo sapiens_hsa051430.73783004
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73654306
96Collecting duct acid secretion_Homo sapiens_hsa049660.73540721
97Malaria_Homo sapiens_hsa051440.73214955
98Colorectal cancer_Homo sapiens_hsa052100.72886261
99Renal cell carcinoma_Homo sapiens_hsa052110.72571049
100Ras signaling pathway_Homo sapiens_hsa040140.72225988
101Transcriptional misregulation in cancer_Homo sapiens_hsa052020.71600969
102Salmonella infection_Homo sapiens_hsa051320.70608693
103Prolactin signaling pathway_Homo sapiens_hsa049170.70529887
104Influenza A_Homo sapiens_hsa051640.70343576
105Jak-STAT signaling pathway_Homo sapiens_hsa046300.69616645
106Fatty acid biosynthesis_Homo sapiens_hsa000610.67382693
107Platelet activation_Homo sapiens_hsa046110.67370413
108Vascular smooth muscle contraction_Homo sapiens_hsa042700.66251932
109Hepatitis B_Homo sapiens_hsa051610.65919985
110Carbohydrate digestion and absorption_Homo sapiens_hsa049730.64684169
111Estrogen signaling pathway_Homo sapiens_hsa049150.64294049
112Phagosome_Homo sapiens_hsa041450.64135023
113Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.64094090
114Regulation of actin cytoskeleton_Homo sapiens_hsa048100.63789512
115Chronic myeloid leukemia_Homo sapiens_hsa052200.62719710
116Glycerolipid metabolism_Homo sapiens_hsa005610.62568108
117Toxoplasmosis_Homo sapiens_hsa051450.62542278
118Rap1 signaling pathway_Homo sapiens_hsa040150.62502119
119Pertussis_Homo sapiens_hsa051330.62447897
120Non-small cell lung cancer_Homo sapiens_hsa052230.61779131
121Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60242855
122Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.59133987
123Shigellosis_Homo sapiens_hsa051310.58428060
124Endocytosis_Homo sapiens_hsa041440.58341573
125Glycosaminoglycan degradation_Homo sapiens_hsa005310.56792995
126VEGF signaling pathway_Homo sapiens_hsa043700.53764601
127Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.53602100
128Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52388487
129Bile secretion_Homo sapiens_hsa049760.51394735
130Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.50181101
131Histidine metabolism_Homo sapiens_hsa003400.49253210
132AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.48648512

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