Rank | Gene Set | Z-score |
---|---|---|
1 | COPI coating of Golgi vesicle (GO:0048205) | 7.01779774 |
2 | Golgi transport vesicle coating (GO:0048200) | 7.01779774 |
3 | protein maturation by protein folding (GO:0022417) | 4.23817821 |
4 | cullin deneddylation (GO:0010388) | 4.18127483 |
5 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 4.17182717 |
6 | protein deneddylation (GO:0000338) | 3.68624296 |
7 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.67107940 |
8 | proteasome assembly (GO:0043248) | 3.64774154 |
9 | protein retention in ER lumen (GO:0006621) | 3.51535439 |
10 | ER overload response (GO:0006983) | 3.35276924 |
11 | COPII vesicle coating (GO:0048208) | 3.27289877 |
12 | vesicle coating (GO:0006901) | 3.23957855 |
13 | DNA double-strand break processing (GO:0000729) | 3.11290615 |
14 | protein localization to kinetochore (GO:0034501) | 3.00697629 |
15 | DNA damage response, detection of DNA damage (GO:0042769) | 3.00135258 |
16 | histone H2A acetylation (GO:0043968) | 2.87223234 |
17 | metaphase plate congression (GO:0051310) | 2.85226106 |
18 | DNA ligation (GO:0006266) | 2.81601780 |
19 | cholesterol biosynthetic process (GO:0006695) | 2.75186671 |
20 | mitotic metaphase plate congression (GO:0007080) | 2.75088650 |
21 | de novo protein folding (GO:0006458) | 2.73321600 |
22 | signal peptide processing (GO:0006465) | 2.71887196 |
23 | establishment of integrated proviral latency (GO:0075713) | 2.64225684 |
24 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.63900246 |
25 | chromatin remodeling at centromere (GO:0031055) | 2.61654858 |
26 | CENP-A containing nucleosome assembly (GO:0034080) | 2.58792223 |
27 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.57807169 |
28 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.56709887 |
29 | protein neddylation (GO:0045116) | 2.55921817 |
30 | sterol biosynthetic process (GO:0016126) | 2.55346584 |
31 | ventricular cardiac muscle cell development (GO:0055015) | 2.54028415 |
32 | spindle checkpoint (GO:0031577) | 2.53676891 |
33 | positive regulation of nuclease activity (GO:0032075) | 2.52786416 |
34 | de novo posttranslational protein folding (GO:0051084) | 2.52577959 |
35 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.50971923 |
36 | nuclear pore organization (GO:0006999) | 2.50005124 |
37 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.49543962 |
38 | chaperone-mediated protein folding (GO:0061077) | 2.49089152 |
39 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.48560733 |
40 | non-recombinational repair (GO:0000726) | 2.48560733 |
41 | peptide hormone processing (GO:0016486) | 2.46344917 |
42 | positive regulation of cellular response to oxidative stress (GO:1900409) | 2.45718001 |
43 | positive regulation of response to oxidative stress (GO:1902884) | 2.45718001 |
44 | mitotic sister chromatid segregation (GO:0000070) | 2.44100897 |
45 | organelle disassembly (GO:1903008) | 2.43709120 |
46 | positive regulation of mitochondrial fission (GO:0090141) | 2.43196039 |
47 | sister chromatid segregation (GO:0000819) | 2.42614960 |
48 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.42446918 |
49 | peptidyl-proline modification (GO:0018208) | 2.41198142 |
50 | chondrocyte development (GO:0002063) | 2.40570268 |
51 | mitotic spindle checkpoint (GO:0071174) | 2.40386876 |
52 | histone arginine methylation (GO:0034969) | 2.40318502 |
53 | negative regulation of microtubule polymerization (GO:0031115) | 2.37719561 |
54 | ER to Golgi vesicle-mediated transport (GO:0006888) | 2.36785013 |
55 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.36274986 |
56 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.34526354 |
57 | lipid particle organization (GO:0034389) | 2.34118801 |
58 | regulation of coenzyme metabolic process (GO:0051196) | 2.33215347 |
59 | regulation of cofactor metabolic process (GO:0051193) | 2.33215347 |
60 | negative regulation of DNA recombination (GO:0045910) | 2.32990285 |
61 | apical protein localization (GO:0045176) | 2.31247983 |
62 | histone exchange (GO:0043486) | 2.30664240 |
63 | regulation of nuclease activity (GO:0032069) | 2.30405573 |
64 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.29863250 |
65 | regulation of centriole replication (GO:0046599) | 2.28746726 |
66 | formation of translation preinitiation complex (GO:0001731) | 2.28676795 |
67 | establishment of viral latency (GO:0019043) | 2.28672402 |
68 | kinetochore organization (GO:0051383) | 2.28468174 |
69 | nuclear pore complex assembly (GO:0051292) | 2.28381068 |
70 | body morphogenesis (GO:0010171) | 2.28357132 |
71 | peptidyl-arginine methylation (GO:0018216) | 2.28040459 |
72 | peptidyl-arginine N-methylation (GO:0035246) | 2.28040459 |
73 | mitotic spindle organization (GO:0007052) | 2.26840984 |
74 | protein localization to chromosome, centromeric region (GO:0071459) | 2.26054464 |
75 | protein K11-linked ubiquitination (GO:0070979) | 2.25329616 |
76 | regulation of mitotic spindle organization (GO:0060236) | 2.23009556 |
77 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.22843261 |
78 | resolution of meiotic recombination intermediates (GO:0000712) | 2.21986331 |
79 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.21921003 |
80 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.21921003 |
81 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.21883336 |
82 | protein N-linked glycosylation via asparagine (GO:0018279) | 2.20653556 |
83 | isoprenoid biosynthetic process (GO:0008299) | 2.20592182 |
84 | L-serine metabolic process (GO:0006563) | 2.19899302 |
85 | polarized epithelial cell differentiation (GO:0030859) | 2.19575479 |
86 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.19520994 |
87 | negative regulation of ligase activity (GO:0051352) | 2.19520994 |
88 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.18875947 |
89 | ATP synthesis coupled proton transport (GO:0015986) | 2.18875947 |
90 | peptidyl-asparagine modification (GO:0018196) | 2.17970770 |
91 | nucleobase biosynthetic process (GO:0046112) | 2.17843157 |
92 | microtubule depolymerization (GO:0007019) | 2.17833879 |
93 | limb bud formation (GO:0060174) | 2.16873091 |
94 | endocrine pancreas development (GO:0031018) | 2.16774554 |
95 | tRNA aminoacylation for protein translation (GO:0006418) | 2.16773492 |
96 | intraciliary transport (GO:0042073) | 2.16752000 |
97 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.16661187 |
98 | establishment of chromosome localization (GO:0051303) | 2.16489075 |
99 | female gonad development (GO:0008585) | 2.16041727 |
100 | protein localization to chromosome (GO:0034502) | 2.15823797 |
101 | sequestering of metal ion (GO:0051238) | 2.15663842 |
102 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.15525182 |
103 | peptidyl-cysteine modification (GO:0018198) | 2.15356679 |
104 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 2.13761335 |
105 | spindle assembly checkpoint (GO:0071173) | 2.13720985 |
106 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.13578294 |
107 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.13578294 |
108 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.13578294 |
109 | negative regulation of sister chromatid segregation (GO:0033046) | 2.13578294 |
110 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.13578294 |
111 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.12929687 |
112 | dopamine biosynthetic process (GO:0042416) | 2.12075021 |
113 | tricarboxylic acid cycle (GO:0006099) | 2.11189371 |
114 | DNA unwinding involved in DNA replication (GO:0006268) | 2.11090775 |
115 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.10916811 |
116 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.10916811 |
117 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 2.10834052 |
118 | mitotic spindle assembly checkpoint (GO:0007094) | 2.10601275 |
119 | cellular response to topologically incorrect protein (GO:0035967) | 2.10166923 |
120 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 2.10142786 |
121 | regulation of gene silencing by miRNA (GO:0060964) | 2.09375270 |
122 | regulation of gene silencing by RNA (GO:0060966) | 2.09375270 |
123 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.09375270 |
124 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.09178589 |
125 | amino acid activation (GO:0043038) | 2.08719534 |
126 | tRNA aminoacylation (GO:0043039) | 2.08719534 |
127 | toxin metabolic process (GO:0009404) | 2.08621104 |
128 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.08335738 |
129 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.08201694 |
130 | negative regulation of chromosome segregation (GO:0051985) | 2.08097769 |
131 | presynaptic membrane assembly (GO:0097105) | 2.07943521 |
132 | cellular response to unfolded protein (GO:0034620) | 2.07618903 |
133 | collagen fibril organization (GO:0030199) | 2.07474046 |
134 | mitotic sister chromatid cohesion (GO:0007064) | 2.07095533 |
135 | regulation of chromosome segregation (GO:0051983) | 2.06501351 |
136 | ribosome assembly (GO:0042255) | 2.06216319 |
137 | regulation of spindle organization (GO:0090224) | 2.05099701 |
138 | aldehyde catabolic process (GO:0046185) | 2.04376438 |
139 | protein localization to cilium (GO:0061512) | 2.02695202 |
140 | 7-methylguanosine mRNA capping (GO:0006370) | 2.02317583 |
141 | protein N-linked glycosylation (GO:0006487) | 2.02247958 |
142 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.02218276 |
143 | ER-nucleus signaling pathway (GO:0006984) | 2.02078673 |
144 | chaperone-mediated protein transport (GO:0072321) | 2.01596663 |
145 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.01574135 |
146 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.01574135 |
147 | intra-Golgi vesicle-mediated transport (GO:0006891) | 2.01377861 |
148 | RNA capping (GO:0036260) | 2.00743150 |
149 | 7-methylguanosine RNA capping (GO:0009452) | 2.00743150 |
150 | ribonucleoprotein complex disassembly (GO:0032988) | 2.00699659 |
151 | establishment of monopolar cell polarity (GO:0061162) | 2.00580048 |
152 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.00580048 |
153 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 1.99675615 |
154 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 1.99338632 |
155 | positive regulation of receptor biosynthetic process (GO:0010870) | 1.99254157 |
156 | purine nucleobase biosynthetic process (GO:0009113) | 1.98955528 |
157 | DNA replication-independent nucleosome assembly (GO:0006336) | 1.98779449 |
158 | DNA replication-independent nucleosome organization (GO:0034724) | 1.98779449 |
159 | detection of calcium ion (GO:0005513) | 1.98704649 |
160 | kinetochore assembly (GO:0051382) | 1.98407190 |
161 | transferrin transport (GO:0033572) | 1.97583004 |
162 | type B pancreatic cell development (GO:0003323) | 1.96872157 |
163 | protein folding (GO:0006457) | 1.96112944 |
164 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 1.95714986 |
165 | response to hepatocyte growth factor (GO:0035728) | 1.95182630 |
166 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 1.95182630 |
167 | positive regulation of ligase activity (GO:0051351) | 1.94282709 |
168 | protein K6-linked ubiquitination (GO:0085020) | 1.94104537 |
169 | establishment of apical/basal cell polarity (GO:0035089) | 1.93934913 |
170 | lactate metabolic process (GO:0006089) | 1.93477068 |
171 | DNA replication-dependent nucleosome assembly (GO:0006335) | 1.92809188 |
172 | DNA replication-dependent nucleosome organization (GO:0034723) | 1.92809188 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.83527786 |
2 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.57422967 |
3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.08982478 |
4 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.04341973 |
5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.80762205 |
6 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.53478944 |
7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.52909079 |
8 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.45727987 |
9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.23028870 |
10 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.19434903 |
11 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.19166595 |
12 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.14034326 |
13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.10610842 |
14 | * ELK1_19687146_ChIP-ChIP_HELA_Human | 2.10350275 |
15 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.10247876 |
16 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.09104189 |
17 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.03158914 |
18 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.98968222 |
19 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.95060816 |
20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.92666161 |
21 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.89356898 |
22 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.87780966 |
23 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.86483090 |
24 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.86155941 |
25 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.85064054 |
26 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.79372616 |
27 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.78998110 |
28 | * WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.78028301 |
29 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.76782593 |
30 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.76703303 |
31 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.76478271 |
32 | FUS_26573619_Chip-Seq_HEK293_Human | 1.73301389 |
33 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.72861055 |
34 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.72769369 |
35 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.72015994 |
36 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.66914562 |
37 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.63229846 |
38 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.62887409 |
39 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.61037587 |
40 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.60082035 |
41 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.55910857 |
42 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.54783649 |
43 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.54205564 |
44 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.52876269 |
45 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.52363780 |
46 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.50125682 |
47 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.47346658 |
48 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.46775808 |
49 | P300_19829295_ChIP-Seq_ESCs_Human | 1.44770613 |
50 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.44252190 |
51 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.41692818 |
52 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.41572269 |
53 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.41498479 |
54 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 1.41203235 |
55 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.41144028 |
56 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.37882120 |
57 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.37697667 |
58 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.36928223 |
59 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.35812814 |
60 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.35730260 |
61 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.35187702 |
62 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.34953410 |
63 | * NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.34498760 |
64 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.33823453 |
65 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.33434314 |
66 | * DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.33266643 |
67 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.32836929 |
68 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.31708026 |
69 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.31427479 |
70 | VDR_22108803_ChIP-Seq_LS180_Human | 1.31046829 |
71 | * SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.30910999 |
72 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.27912859 |
73 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.26040848 |
74 | EWS_26573619_Chip-Seq_HEK293_Human | 1.25855823 |
75 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.23350272 |
76 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.19343081 |
77 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.17537830 |
78 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.16924633 |
79 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.14713846 |
80 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.14234172 |
81 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.14086689 |
82 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.14036281 |
83 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.13745009 |
84 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.12965564 |
85 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.12286084 |
86 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.10873455 |
87 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.10824280 |
88 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.10744762 |
89 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.10108062 |
90 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.09893676 |
91 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 1.08652008 |
92 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.06870351 |
93 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.06423309 |
94 | * CLOCK_20551151_ChIP-Seq_293T_Human | 1.04981958 |
95 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.04528361 |
96 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.04347055 |
97 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.03881672 |
98 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.03430974 |
99 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.03072291 |
100 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.02536435 |
101 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.01952760 |
102 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.01344196 |
103 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.01279276 |
104 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.01279276 |
105 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.01279276 |
106 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.00096570 |
107 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.99776407 |
108 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.99632367 |
109 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.98970356 |
110 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.97798292 |
111 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.97539834 |
112 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.97175929 |
113 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.96698221 |
114 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.96042093 |
115 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.94669093 |
116 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.94140736 |
117 | JUN_21703547_ChIP-Seq_K562_Human | 0.93984461 |
118 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.93972311 |
119 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.93967535 |
120 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.92983848 |
121 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.91574351 |
122 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.90768418 |
123 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.89770497 |
124 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.89682117 |
125 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.87044619 |
126 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.86677234 |
127 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.85988009 |
128 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.85677844 |
129 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.84495203 |
130 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.84091150 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003122_maternal_imprinting | 3.92021021 |
2 | MP0003123_paternal_imprinting | 3.58298380 |
3 | MP0003283_abnormal_digestive_organ | 3.01935819 |
4 | MP0003121_genomic_imprinting | 2.81338376 |
5 | MP0008438_abnormal_cutaneous_collagen | 2.53829023 |
6 | MP0000013_abnormal_adipose_tissue | 2.36895104 |
7 | MP0010386_abnormal_urinary_bladder | 2.16640611 |
8 | MP0002102_abnormal_ear_morphology | 2.13582159 |
9 | MP0009780_abnormal_chondrocyte_physiolo | 2.12297754 |
10 | MP0008058_abnormal_DNA_repair | 2.07177803 |
11 | MP0004272_abnormal_basement_membrane | 2.01244519 |
12 | MP0000537_abnormal_urethra_morphology | 1.92857878 |
13 | MP0005503_abnormal_tendon_morphology | 1.86917495 |
14 | MP0003119_abnormal_digestive_system | 1.78245161 |
15 | MP0002909_abnormal_adrenal_gland | 1.73721908 |
16 | MP0010094_abnormal_chromosome_stability | 1.69645950 |
17 | MP0002877_abnormal_melanocyte_morpholog | 1.67655081 |
18 | MP0003787_abnormal_imprinting | 1.67495652 |
19 | MP0008789_abnormal_olfactory_epithelium | 1.66652155 |
20 | MP0004957_abnormal_blastocyst_morpholog | 1.63089780 |
21 | MP0009697_abnormal_copulation | 1.62075679 |
22 | MP0006054_spinal_hemorrhage | 1.60190645 |
23 | MP0003890_abnormal_embryonic-extraembry | 1.59638798 |
24 | MP0004133_heterotaxia | 1.55811923 |
25 | MP0005394_taste/olfaction_phenotype | 1.54178148 |
26 | MP0005499_abnormal_olfactory_system | 1.54178148 |
27 | MP0003942_abnormal_urinary_system | 1.51018717 |
28 | MP0008932_abnormal_embryonic_tissue | 1.49278180 |
29 | MP0010030_abnormal_orbit_morphology | 1.49144227 |
30 | MP0003941_abnormal_skin_development | 1.48651746 |
31 | MP0004264_abnormal_extraembryonic_tissu | 1.47997769 |
32 | MP0006072_abnormal_retinal_apoptosis | 1.47116399 |
33 | MP0004270_analgesia | 1.38732723 |
34 | MP0003718_maternal_effect | 1.38435279 |
35 | MP0001299_abnormal_eye_distance/ | 1.38064791 |
36 | MP0001984_abnormal_olfaction | 1.36738096 |
37 | MP0005275_abnormal_skin_tensile | 1.36244451 |
38 | MP0005623_abnormal_meninges_morphology | 1.35417806 |
39 | MP0001293_anophthalmia | 1.35264131 |
40 | MP0003937_abnormal_limbs/digits/tail_de | 1.34511366 |
41 | MP0002896_abnormal_bone_mineralization | 1.33425883 |
42 | MP0002938_white_spotting | 1.33259171 |
43 | MP0000631_abnormal_neuroendocrine_gland | 1.32163460 |
44 | MP0005187_abnormal_penis_morphology | 1.28823813 |
45 | MP0002751_abnormal_autonomic_nervous | 1.26248379 |
46 | MP0000462_abnormal_digestive_system | 1.25940507 |
47 | MP0000372_irregular_coat_pigmentation | 1.24788618 |
48 | MP0006276_abnormal_autonomic_nervous | 1.22728578 |
49 | MP0003385_abnormal_body_wall | 1.22403150 |
50 | MP0002837_dystrophic_cardiac_calcinosis | 1.22119741 |
51 | MP0003111_abnormal_nucleus_morphology | 1.21442110 |
52 | MP0003880_abnormal_central_pattern | 1.21231431 |
53 | MP0002084_abnormal_developmental_patter | 1.18331662 |
54 | MP0002697_abnormal_eye_size | 1.17492624 |
55 | MP0004134_abnormal_chest_morphology | 1.16912092 |
56 | MP0001944_abnormal_pancreas_morphology | 1.14848805 |
57 | MP0003755_abnormal_palate_morphology | 1.14239846 |
58 | MP0000678_abnormal_parathyroid_gland | 1.13990579 |
59 | MP0009046_muscle_twitch | 1.13212820 |
60 | MP0009250_abnormal_appendicular_skeleto | 1.12979695 |
61 | MP0001529_abnormal_vocalization | 1.12831574 |
62 | MP0002653_abnormal_ependyma_morphology | 1.11127393 |
63 | MP0000647_abnormal_sebaceous_gland | 1.10164237 |
64 | MP0001177_atelectasis | 1.07446417 |
65 | MP0004197_abnormal_fetal_growth/weight/ | 1.06920713 |
66 | MP0000778_abnormal_nervous_system | 1.05968858 |
67 | MP0002184_abnormal_innervation | 1.05911437 |
68 | MP0002282_abnormal_trachea_morphology | 1.03708735 |
69 | MP0002734_abnormal_mechanical_nocicepti | 1.02792195 |
70 | MP0000428_abnormal_craniofacial_morphol | 1.01990222 |
71 | MP0000049_abnormal_middle_ear | 1.01883304 |
72 | MP0005253_abnormal_eye_physiology | 1.01236782 |
73 | MP0002736_abnormal_nociception_after | 1.00720642 |
74 | MP0000003_abnormal_adipose_tissue | 1.00602711 |
75 | MP0003567_abnormal_fetal_cardiomyocyte | 1.00496381 |
76 | MP0001286_abnormal_eye_development | 1.00412624 |
77 | MP0004233_abnormal_muscle_weight | 0.99203047 |
78 | MP0003786_premature_aging | 0.98893362 |
79 | MP0003693_abnormal_embryo_hatching | 0.98610160 |
80 | MP0000534_abnormal_ureter_morphology | 0.98500955 |
81 | MP0001730_embryonic_growth_arrest | 0.98464276 |
82 | MP0002234_abnormal_pharynx_morphology | 0.97842799 |
83 | MP0005220_abnormal_exocrine_pancreas | 0.97479362 |
84 | MP0005379_endocrine/exocrine_gland_phen | 0.97248146 |
85 | MP0002693_abnormal_pancreas_physiology | 0.94547232 |
86 | MP0001697_abnormal_embryo_size | 0.92541780 |
87 | MP0002085_abnormal_embryonic_tissue | 0.92454448 |
88 | MP0006292_abnormal_olfactory_placode | 0.91787632 |
89 | MP0009672_abnormal_birth_weight | 0.91427177 |
90 | MP0005645_abnormal_hypothalamus_physiol | 0.91134511 |
91 | MP0005508_abnormal_skeleton_morphology | 0.90666139 |
92 | MP0002111_abnormal_tail_morphology | 0.89749558 |
93 | MP0002116_abnormal_craniofacial_bone | 0.89349932 |
94 | MP0008995_early_reproductive_senescence | 0.88450700 |
95 | MP0002177_abnormal_outer_ear | 0.88382249 |
96 | MP0003635_abnormal_synaptic_transmissio | 0.88248610 |
97 | MP0000516_abnormal_urinary_system | 0.88237610 |
98 | MP0005367_renal/urinary_system_phenotyp | 0.88237610 |
99 | MP0008057_abnormal_DNA_replication | 0.87841904 |
100 | MP0002160_abnormal_reproductive_system | 0.87534193 |
101 | MP0000163_abnormal_cartilage_morphology | 0.87345717 |
102 | MP0002090_abnormal_vision | 0.86776071 |
103 | MP0003861_abnormal_nervous_system | 0.85759932 |
104 | MP0000566_synostosis | 0.85515072 |
105 | MP0004215_abnormal_myocardial_fiber | 0.84353431 |
106 | MP0004043_abnormal_pH_regulation | 0.84146436 |
107 | MP0010352_gastrointestinal_tract_polyps | 0.83915609 |
108 | MP0005646_abnormal_pituitary_gland | 0.83633517 |
109 | MP0005391_vision/eye_phenotype | 0.82794997 |
110 | MP0002210_abnormal_sex_determination | 0.82602578 |
111 | MP0001188_hyperpigmentation | 0.82463105 |
112 | MP0003115_abnormal_respiratory_system | 0.82250422 |
113 | MP0009053_abnormal_anal_canal | 0.81900062 |
114 | MP0002063_abnormal_learning/memory/cond | 0.81842599 |
115 | MP0004147_increased_porphyrin_level | 0.81698635 |
116 | MP0003221_abnormal_cardiomyocyte_apopto | 0.81600639 |
117 | MP0006035_abnormal_mitochondrial_morpho | 0.80779693 |
118 | MP0002233_abnormal_nose_morphology | 0.80162300 |
119 | MP0005380_embryogenesis_phenotype | 0.79920765 |
120 | MP0001672_abnormal_embryogenesis/_devel | 0.79920765 |
121 | MP0000955_abnormal_spinal_cord | 0.79560754 |
122 | MP0005551_abnormal_eye_electrophysiolog | 0.78219291 |
123 | MP0001929_abnormal_gametogenesis | 0.78016252 |
124 | MP0004859_abnormal_synaptic_plasticity | 0.77969933 |
125 | MP0001486_abnormal_startle_reflex | 0.77849216 |
126 | MP0003935_abnormal_craniofacial_develop | 0.76904004 |
127 | MP0009703_decreased_birth_body | 0.76638673 |
128 | MP0005171_absent_coat_pigmentation | 0.76559027 |
129 | MP0005248_abnormal_Harderian_gland | 0.76482307 |
130 | MP0008007_abnormal_cellular_replicative | 0.75716380 |
131 | MP0000358_abnormal_cell_content/ | 0.75529489 |
132 | MP0002114_abnormal_axial_skeleton | 0.75024385 |
133 | MP0003183_abnormal_peptide_metabolism | 0.74174690 |
134 | MP0003705_abnormal_hypodermis_morpholog | 0.73355187 |
135 | MP0002557_abnormal_social/conspecific_i | 0.73217491 |
136 | MP0003186_abnormal_redox_activity | 0.72672820 |
137 | MP0004811_abnormal_neuron_physiology | 0.72025324 |
138 | MP0008877_abnormal_DNA_methylation | 0.71831038 |
139 | MP0003077_abnormal_cell_cycle | 0.71725030 |
140 | MP0002152_abnormal_brain_morphology | 0.71051637 |
141 | MP0001905_abnormal_dopamine_level | 0.70348636 |
142 | MP0003315_abnormal_perineum_morphology | 0.70238372 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of dentin (HP:0010299) | 3.02301833 |
2 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.88292609 |
3 | Hepatoblastoma (HP:0002884) | 2.69818810 |
4 | Cortical dysplasia (HP:0002539) | 2.62115647 |
5 | Epiphyseal dysplasia (HP:0002656) | 2.48546588 |
6 | Premature rupture of membranes (HP:0001788) | 2.44675795 |
7 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.43409440 |
8 | Irregular epiphyses (HP:0010582) | 2.43250787 |
9 | Shoulder girdle muscle weakness (HP:0003547) | 2.34976926 |
10 | Abnormal lung lobation (HP:0002101) | 2.31877442 |
11 | Volvulus (HP:0002580) | 2.30207615 |
12 | Hypoglycemic seizures (HP:0002173) | 2.29140211 |
13 | Abnormality of the labia minora (HP:0012880) | 2.21972721 |
14 | Protrusio acetabuli (HP:0003179) | 2.21340235 |
15 | Missing ribs (HP:0000921) | 2.15156044 |
16 | Delayed epiphyseal ossification (HP:0002663) | 2.09799151 |
17 | Abnormal pancreas size (HP:0012094) | 2.08721045 |
18 | Symptomatic seizures (HP:0011145) | 2.07487838 |
19 | Bifid tongue (HP:0010297) | 2.04437550 |
20 | Pheochromocytoma (HP:0002666) | 2.02204713 |
21 | Delayed gross motor development (HP:0002194) | 2.00476052 |
22 | Colon cancer (HP:0003003) | 1.98524544 |
23 | Pancreatic fibrosis (HP:0100732) | 1.96527922 |
24 | Hypoplastic pelvis (HP:0008839) | 1.95033099 |
25 | Neuroendocrine neoplasm (HP:0100634) | 1.94150033 |
26 | Spinal cord compression (HP:0002176) | 1.93973367 |
27 | Ependymoma (HP:0002888) | 1.92936543 |
28 | Abnormality of glycolysis (HP:0004366) | 1.91144087 |
29 | Increased serum pyruvate (HP:0003542) | 1.91144087 |
30 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.90907525 |
31 | Orthostatic hypotension (HP:0001278) | 1.90362173 |
32 | Mild short stature (HP:0003502) | 1.89823688 |
33 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.89758088 |
34 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.89758088 |
35 | Single umbilical artery (HP:0001195) | 1.89758088 |
36 | Postnatal microcephaly (HP:0005484) | 1.88758948 |
37 | Neoplasm of the adrenal gland (HP:0100631) | 1.88312995 |
38 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.87971924 |
39 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.87971924 |
40 | Soft skin (HP:0000977) | 1.87750724 |
41 | Acute encephalopathy (HP:0006846) | 1.87396913 |
42 | Atonic seizures (HP:0010819) | 1.85659892 |
43 | Acute necrotizing encephalopathy (HP:0006965) | 1.84453082 |
44 | Short tibia (HP:0005736) | 1.84266694 |
45 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.83630259 |
46 | Increased nuchal translucency (HP:0010880) | 1.82162191 |
47 | Meckel diverticulum (HP:0002245) | 1.81688069 |
48 | Osteomalacia (HP:0002749) | 1.81513242 |
49 | High anterior hairline (HP:0009890) | 1.81431843 |
50 | True hermaphroditism (HP:0010459) | 1.81254121 |
51 | Resting tremor (HP:0002322) | 1.80955574 |
52 | Occipital encephalocele (HP:0002085) | 1.80529764 |
53 | Limb dystonia (HP:0002451) | 1.78911958 |
54 | Flat capital femoral epiphysis (HP:0003370) | 1.77975791 |
55 | Hypoplastic female external genitalia (HP:0012815) | 1.77709047 |
56 | Intestinal atresia (HP:0011100) | 1.75628884 |
57 | Drooling (HP:0002307) | 1.74106830 |
58 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.73938269 |
59 | Abnormality of the ileum (HP:0001549) | 1.73897744 |
60 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.73687155 |
61 | Poor suck (HP:0002033) | 1.73352454 |
62 | Small epiphyses (HP:0010585) | 1.73224809 |
63 | Papillary thyroid carcinoma (HP:0002895) | 1.72998225 |
64 | Epileptiform EEG discharges (HP:0011182) | 1.72918188 |
65 | Upper limb muscle weakness (HP:0003484) | 1.72888436 |
66 | Cervical subluxation (HP:0003308) | 1.72327283 |
67 | EEG with generalized epileptiform discharges (HP:0011198) | 1.72054925 |
68 | Wormian bones (HP:0002645) | 1.71748107 |
69 | Abnormality of the anterior horn cell (HP:0006802) | 1.71444967 |
70 | Degeneration of anterior horn cells (HP:0002398) | 1.71444967 |
71 | Pancreatic cysts (HP:0001737) | 1.71276464 |
72 | Glossoptosis (HP:0000162) | 1.71142793 |
73 | Gait imbalance (HP:0002141) | 1.70210570 |
74 | Metaphyseal cupping (HP:0003021) | 1.69312938 |
75 | Glioma (HP:0009733) | 1.69094012 |
76 | Bell-shaped thorax (HP:0001591) | 1.68843620 |
77 | Preaxial hand polydactyly (HP:0001177) | 1.68505369 |
78 | Hypoplasia of the pons (HP:0012110) | 1.68332531 |
79 | Hypsarrhythmia (HP:0002521) | 1.68140548 |
80 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.66272662 |
81 | Vertebral hypoplasia (HP:0008417) | 1.66272662 |
82 | Postaxial hand polydactyly (HP:0001162) | 1.66261568 |
83 | Broad foot (HP:0001769) | 1.65927706 |
84 | Decreased testicular size (HP:0008734) | 1.65516643 |
85 | Congenital primary aphakia (HP:0007707) | 1.65168670 |
86 | Molar tooth sign on MRI (HP:0002419) | 1.64983303 |
87 | Abnormality of midbrain morphology (HP:0002418) | 1.64983303 |
88 | Back pain (HP:0003418) | 1.64613683 |
89 | Lissencephaly (HP:0001339) | 1.64028300 |
90 | Agitation (HP:0000713) | 1.63607014 |
91 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.62724915 |
92 | Abnormality of the calcaneus (HP:0008364) | 1.62434605 |
93 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.62300150 |
94 | Abnormality of the pons (HP:0007361) | 1.62070059 |
95 | Astrocytoma (HP:0009592) | 1.61612281 |
96 | Abnormality of the astrocytes (HP:0100707) | 1.61612281 |
97 | Supernumerary spleens (HP:0009799) | 1.61499342 |
98 | Small intestinal stenosis (HP:0012848) | 1.61413620 |
99 | Duodenal stenosis (HP:0100867) | 1.61413620 |
100 | Congenital glaucoma (HP:0001087) | 1.61411219 |
101 | Tubulointerstitial nephritis (HP:0001970) | 1.60746780 |
102 | Cholecystitis (HP:0001082) | 1.60114056 |
103 | Abnormal gallbladder physiology (HP:0012438) | 1.60114056 |
104 | Buphthalmos (HP:0000557) | 1.59866401 |
105 | Abnormality of methionine metabolism (HP:0010901) | 1.59227679 |
106 | Testicular neoplasm (HP:0010788) | 1.59223913 |
107 | Increased CSF lactate (HP:0002490) | 1.58886379 |
108 | Abnormality of chromosome stability (HP:0003220) | 1.58834412 |
109 | Irregular vertebral endplates (HP:0003301) | 1.58649567 |
110 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.58436140 |
111 | Retinal dysplasia (HP:0007973) | 1.58384686 |
112 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.58352708 |
113 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.58352708 |
114 | Abnormal protein glycosylation (HP:0012346) | 1.58352708 |
115 | Abnormal glycosylation (HP:0012345) | 1.58352708 |
116 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.58197355 |
117 | Abnormality of the labia (HP:0000058) | 1.58097100 |
118 | Pelvic girdle muscle weakness (HP:0003749) | 1.57717175 |
119 | Labial hypoplasia (HP:0000066) | 1.57555316 |
120 | Methylmalonic acidemia (HP:0002912) | 1.56770699 |
121 | Spastic diplegia (HP:0001264) | 1.56564555 |
122 | Postaxial foot polydactyly (HP:0001830) | 1.56465555 |
123 | Poor coordination (HP:0002370) | 1.55896444 |
124 | Relative macrocephaly (HP:0004482) | 1.55614886 |
125 | Progressive macrocephaly (HP:0004481) | 1.55059500 |
126 | Vaginal atresia (HP:0000148) | 1.54845534 |
127 | Renal hypoplasia (HP:0000089) | 1.53810105 |
128 | Genital tract atresia (HP:0001827) | 1.53794785 |
129 | 11 pairs of ribs (HP:0000878) | 1.53789140 |
130 | Stenosis of the external auditory canal (HP:0000402) | 1.53504609 |
131 | Disproportionate short-trunk short stature (HP:0003521) | 1.53478561 |
132 | Hypothermia (HP:0002045) | 1.52701580 |
133 | Myelomeningocele (HP:0002475) | 1.52327183 |
134 | Patent foramen ovale (HP:0001655) | 1.52116709 |
135 | Dysautonomia (HP:0002459) | 1.51917552 |
136 | Optic nerve hypoplasia (HP:0000609) | 1.51908941 |
137 | Dental crowding (HP:0000678) | 1.51707041 |
138 | Muscular hypotonia of the trunk (HP:0008936) | 1.51505060 |
139 | Abnormality of the duodenum (HP:0002246) | 1.50514953 |
140 | Thoracolumbar scoliosis (HP:0002944) | 1.50490334 |
141 | Osteoarthritis (HP:0002758) | 1.50391363 |
142 | Abnormal autonomic nervous system physiology (HP:0012332) | 1.50366049 |
143 | Cerebral edema (HP:0002181) | 1.49389201 |
144 | Broad long bones (HP:0005622) | 1.49182775 |
145 | Medial flaring of the eyebrow (HP:0010747) | 1.48647834 |
146 | Micropenis (HP:0000054) | 1.48536577 |
147 | Facial cleft (HP:0002006) | 1.48381682 |
148 | Hypoventilation (HP:0002791) | 1.48279930 |
149 | Dandy-Walker malformation (HP:0001305) | 1.48229944 |
150 | Intestinal polyposis (HP:0200008) | 1.48155006 |
151 | X-linked dominant inheritance (HP:0001423) | 1.47671809 |
152 | Oligodactyly (hands) (HP:0001180) | 1.47368647 |
153 | Adrenal hypoplasia (HP:0000835) | 1.47188436 |
154 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.46583562 |
155 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.46583562 |
156 | Type II lissencephaly (HP:0007260) | 1.45989031 |
157 | Nephronophthisis (HP:0000090) | 1.45916590 |
158 | Nephrogenic diabetes insipidus (HP:0009806) | 1.45884744 |
159 | Curly hair (HP:0002212) | 1.45585424 |
160 | Broad phalanx (HP:0006009) | 1.45356621 |
161 | Bladder diverticulum (HP:0000015) | 1.44932975 |
162 | Type I transferrin isoform profile (HP:0003642) | 1.44466957 |
163 | Hyperthyroidism (HP:0000836) | 1.44376776 |
164 | Fibular hypoplasia (HP:0003038) | 1.44232967 |
165 | Overlapping toe (HP:0001845) | 1.43581403 |
166 | Split foot (HP:0001839) | 1.42320368 |
167 | Chorioretinal coloboma (HP:0000567) | 1.40386836 |
168 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.39943384 |
169 | Scrotal hypoplasia (HP:0000046) | 1.39074563 |
170 | Hyperglycinemia (HP:0002154) | 1.38908608 |
171 | Microglossia (HP:0000171) | 1.38157064 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PASK | 3.46004846 |
2 | TRIM28 | 3.33710546 |
3 | SCYL2 | 2.61350638 |
4 | LIMK1 | 2.38958218 |
5 | TSSK6 | 2.36898810 |
6 | BCR | 2.30178887 |
7 | PLK2 | 2.18665573 |
8 | NTRK3 | 2.12455100 |
9 | MAP4K2 | 2.11988055 |
10 | BUB1 | 1.99341200 |
11 | EPHA4 | 1.95869231 |
12 | PBK | 1.94285928 |
13 | PLK3 | 1.93793237 |
14 | EIF2AK3 | 1.93574707 |
15 | WNK3 | 1.86910772 |
16 | PNCK | 1.77282318 |
17 | DDR2 | 1.73837800 |
18 | CASK | 1.73128360 |
19 | UHMK1 | 1.72517640 |
20 | ERBB3 | 1.69045050 |
21 | BRSK2 | 1.62892741 |
22 | TESK1 | 1.61854582 |
23 | FER | 1.52743387 |
24 | LATS2 | 1.50327996 |
25 | FRK | 1.49664827 |
26 | LATS1 | 1.44751606 |
27 | PDK2 | 1.39334580 |
28 | NTRK1 | 1.38379727 |
29 | SRPK1 | 1.37163507 |
30 | MAP3K4 | 1.36524608 |
31 | CSNK1G3 | 1.35863361 |
32 | CDC7 | 1.32544324 |
33 | KSR1 | 1.31832149 |
34 | MAP3K12 | 1.28612814 |
35 | WEE1 | 1.28596605 |
36 | NEK1 | 1.27627066 |
37 | MKNK1 | 1.27546089 |
38 | MET | 1.26509518 |
39 | PAK3 | 1.24648460 |
40 | MINK1 | 1.24370842 |
41 | EPHA2 | 1.22430044 |
42 | MAP3K2 | 1.19311910 |
43 | ACVR1B | 1.18571287 |
44 | PDGFRA | 1.17344916 |
45 | STK38L | 1.11457751 |
46 | ARAF | 1.10805620 |
47 | CSNK1G2 | 1.09465873 |
48 | BRAF | 1.09041809 |
49 | VRK1 | 1.06909599 |
50 | SIK3 | 1.05512598 |
51 | CSNK1A1L | 1.05485107 |
52 | NME1 | 1.05189502 |
53 | CDK14 | 1.03906289 |
54 | AKT3 | 1.01745222 |
55 | MAPK15 | 1.01239336 |
56 | PRKCI | 1.01190915 |
57 | MARK1 | 1.00131936 |
58 | STK16 | 0.98831825 |
59 | DYRK2 | 0.98476354 |
60 | AURKA | 0.96208790 |
61 | CSNK1G1 | 0.94956661 |
62 | TNIK | 0.94680993 |
63 | PRKD3 | 0.93954059 |
64 | TGFBR1 | 0.92385001 |
65 | NUAK1 | 0.91534348 |
66 | WNK4 | 0.91396607 |
67 | BRSK1 | 0.87339764 |
68 | BMPR1B | 0.86637236 |
69 | CDK18 | 0.85779586 |
70 | ZAK | 0.85590899 |
71 | MST4 | 0.85478577 |
72 | ERBB4 | 0.83065329 |
73 | NEK2 | 0.82325502 |
74 | PLK1 | 0.82113653 |
75 | STK39 | 0.81499187 |
76 | INSRR | 0.79943390 |
77 | CDK15 | 0.78977794 |
78 | FGFR1 | 0.78936955 |
79 | PTK2 | 0.77112074 |
80 | FLT3 | 0.72588378 |
81 | EPHB2 | 0.71071262 |
82 | MAP2K7 | 0.70520508 |
83 | CCNB1 | 0.70416849 |
84 | MAPK13 | 0.70066435 |
85 | CDK11A | 0.68894687 |
86 | DYRK3 | 0.68343665 |
87 | ADRBK1 | 0.67075504 |
88 | OXSR1 | 0.65709924 |
89 | CDK8 | 0.65540967 |
90 | PINK1 | 0.64846244 |
91 | RPS6KB2 | 0.63967271 |
92 | EIF2AK2 | 0.62590022 |
93 | ICK | 0.62337145 |
94 | DAPK1 | 0.61909668 |
95 | MAP2K1 | 0.61253208 |
96 | MAP3K9 | 0.59747694 |
97 | TTK | 0.59489530 |
98 | EIF2AK1 | 0.59221043 |
99 | PAK4 | 0.58727546 |
100 | MAPKAPK5 | 0.58391558 |
101 | CDK19 | 0.58053968 |
102 | VRK2 | 0.57745672 |
103 | ATR | 0.56777697 |
104 | PLK4 | 0.56037260 |
105 | KSR2 | 0.55642437 |
106 | CAMK2B | 0.55464594 |
107 | CAMKK2 | 0.54557261 |
108 | GRK5 | 0.53416941 |
109 | ATM | 0.53267859 |
110 | CSNK1E | 0.52562032 |
111 | FGFR2 | 0.52527791 |
112 | PRKCG | 0.50543966 |
113 | CHEK2 | 0.49582681 |
114 | STK3 | 0.48978134 |
115 | DYRK1A | 0.48822226 |
116 | PRKCE | 0.47394019 |
117 | CAMK2A | 0.44809207 |
118 | MKNK2 | 0.44780787 |
119 | PAK6 | 0.43071970 |
120 | PAK1 | 0.42424354 |
121 | AURKB | 0.42349033 |
122 | BCKDK | 0.42229801 |
123 | CHEK1 | 0.42210532 |
124 | RPS6KA4 | 0.40249516 |
125 | CAMK2D | 0.39918851 |
126 | CDK7 | 0.39885420 |
127 | CDK1 | 0.34662947 |
128 | CSNK2A1 | 0.33621257 |
129 | GRK1 | 0.30919162 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protein export_Homo sapiens_hsa03060 | 4.39729295 |
2 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.90969545 |
3 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.75246372 |
4 | Proteasome_Homo sapiens_hsa03050 | 2.64037795 |
5 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 2.46127713 |
6 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.45811702 |
7 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.03913624 |
8 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.98138574 |
9 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.91458546 |
10 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.84130631 |
11 | RNA transport_Homo sapiens_hsa03013 | 1.76590947 |
12 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.70695202 |
13 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.70212945 |
14 | Alcoholism_Homo sapiens_hsa05034 | 1.64050696 |
15 | Spliceosome_Homo sapiens_hsa03040 | 1.59109354 |
16 | RNA polymerase_Homo sapiens_hsa03020 | 1.56889355 |
17 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.56820585 |
18 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.55551509 |
19 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.49199885 |
20 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.48947409 |
21 | Parkinsons disease_Homo sapiens_hsa05012 | 1.48023879 |
22 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.45945580 |
23 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.43769061 |
24 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.43613670 |
25 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.42546832 |
26 | Insulin secretion_Homo sapiens_hsa04911 | 1.42505588 |
27 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.40763600 |
28 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.40626470 |
29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.38831430 |
30 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.38296002 |
31 | Cocaine addiction_Homo sapiens_hsa05030 | 1.32005472 |
32 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.30132882 |
33 | Cell cycle_Homo sapiens_hsa04110 | 1.29937950 |
34 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.27546616 |
35 | Huntingtons disease_Homo sapiens_hsa05016 | 1.25641041 |
36 | Nicotine addiction_Homo sapiens_hsa05033 | 1.25470905 |
37 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.25112759 |
38 | Mismatch repair_Homo sapiens_hsa03430 | 1.24749138 |
39 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.24693207 |
40 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.23285687 |
41 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.23093630 |
42 | Homologous recombination_Homo sapiens_hsa03440 | 1.23076063 |
43 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.22720349 |
44 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.21995338 |
45 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.18677437 |
46 | Carbon metabolism_Homo sapiens_hsa01200 | 1.18509868 |
47 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.16376242 |
48 | Long-term potentiation_Homo sapiens_hsa04720 | 1.15481423 |
49 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.15178285 |
50 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.14319092 |
51 | Alzheimers disease_Homo sapiens_hsa05010 | 1.13771847 |
52 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.12929231 |
53 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.10149170 |
54 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.09880281 |
55 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.06985701 |
56 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.05207024 |
57 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.01661924 |
58 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.01040403 |
59 | RNA degradation_Homo sapiens_hsa03018 | 1.00690808 |
60 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.98148091 |
61 | Phototransduction_Homo sapiens_hsa04744 | 0.97958385 |
62 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.95893994 |
63 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.93613889 |
64 | GABAergic synapse_Homo sapiens_hsa04727 | 0.90934403 |
65 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.90561583 |
66 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.90136240 |
67 | DNA replication_Homo sapiens_hsa03030 | 0.89558500 |
68 | Basal transcription factors_Homo sapiens_hsa03022 | 0.89458828 |
69 | Phagosome_Homo sapiens_hsa04145 | 0.88273847 |
70 | Circadian entrainment_Homo sapiens_hsa04713 | 0.87862769 |
71 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.86871584 |
72 | Gap junction_Homo sapiens_hsa04540 | 0.84818718 |
73 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.84500340 |
74 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.83755497 |
75 | Long-term depression_Homo sapiens_hsa04730 | 0.82292538 |
76 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.81217181 |
77 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.80962965 |
78 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.80824856 |
79 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.80521262 |
80 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.80473864 |
81 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.79780971 |
82 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.79078177 |
83 | Tight junction_Homo sapiens_hsa04530 | 0.77188669 |
84 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.74740173 |
85 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.74706767 |
86 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.73987489 |
87 | Taste transduction_Homo sapiens_hsa04742 | 0.73671182 |
88 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.73383765 |
89 | Axon guidance_Homo sapiens_hsa04360 | 0.71464183 |
90 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.71451910 |
91 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.70432745 |
92 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.66695671 |
93 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.65030908 |
94 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64773024 |
95 | Focal adhesion_Homo sapiens_hsa04510 | 0.64049029 |
96 | Peroxisome_Homo sapiens_hsa04146 | 0.63995473 |
97 | Colorectal cancer_Homo sapiens_hsa05210 | 0.63322446 |
98 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.61729957 |
99 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.60276979 |
100 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.60202555 |
101 | Endometrial cancer_Homo sapiens_hsa05213 | 0.59862256 |
102 | Circadian rhythm_Homo sapiens_hsa04710 | 0.57762001 |
103 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.57721376 |
104 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.57217389 |
105 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.57039553 |
106 | Thyroid cancer_Homo sapiens_hsa05216 | 0.56847804 |
107 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.56800740 |
108 | Bladder cancer_Homo sapiens_hsa05219 | 0.56507483 |
109 | Melanogenesis_Homo sapiens_hsa04916 | 0.56065015 |
110 | Glioma_Homo sapiens_hsa05214 | 0.55404337 |
111 | Ribosome_Homo sapiens_hsa03010 | 0.55032917 |
112 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.54302161 |
113 | Purine metabolism_Homo sapiens_hsa00230 | 0.53348411 |
114 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.53022093 |
115 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.52211096 |
116 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.51689661 |
117 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.51453032 |
118 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.51432672 |
119 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.50691517 |
120 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.50639067 |
121 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.50421163 |
122 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.49920994 |
123 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.49572736 |
124 | Morphine addiction_Homo sapiens_hsa05032 | 0.47934085 |
125 | Prostate cancer_Homo sapiens_hsa05215 | 0.47584769 |
126 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.44853769 |
127 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.44513390 |
128 | Adherens junction_Homo sapiens_hsa04520 | 0.44477511 |
129 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.43863196 |
130 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.43772709 |
131 | Base excision repair_Homo sapiens_hsa03410 | 0.43090951 |
132 | Melanoma_Homo sapiens_hsa05218 | 0.43038251 |
133 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.42396401 |
134 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.41965111 |
135 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.41166141 |
136 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.40873309 |
137 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.39090072 |
138 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.39021997 |
139 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.38022351 |
140 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.36918007 |
141 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.36268845 |
142 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.36201396 |
143 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.33441186 |
144 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.32546166 |