Rank | Gene Set | Z-score |
---|---|---|
1 | axoneme assembly (GO:0035082) | 6.10655199 |
2 | cilium movement (GO:0003341) | 5.46866410 |
3 | cilium or flagellum-dependent cell motility (GO:0001539) | 5.41414109 |
4 | axonemal dynein complex assembly (GO:0070286) | 5.36870649 |
5 | epithelial cilium movement (GO:0003351) | 5.22272790 |
6 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 5.04633558 |
7 | behavioral response to nicotine (GO:0035095) | 4.83714891 |
8 | motile cilium assembly (GO:0044458) | 4.47166685 |
9 | presynaptic membrane assembly (GO:0097105) | 4.29979866 |
10 | presynaptic membrane organization (GO:0097090) | 4.09873826 |
11 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 4.09869359 |
12 | regulation of cilium movement (GO:0003352) | 4.01446221 |
13 | microtubule bundle formation (GO:0001578) | 3.83230780 |
14 | acrosome reaction (GO:0007340) | 3.78498808 |
15 | retinal rod cell development (GO:0046548) | 3.78221628 |
16 | cornea development in camera-type eye (GO:0061303) | 3.69169919 |
17 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.68681982 |
18 | startle response (GO:0001964) | 3.62739944 |
19 | intraciliary transport (GO:0042073) | 3.62281250 |
20 | GTP biosynthetic process (GO:0006183) | 3.62166728 |
21 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.60391953 |
22 | cilium assembly (GO:0042384) | 3.52895533 |
23 | cilium organization (GO:0044782) | 3.49690317 |
24 | neuron cell-cell adhesion (GO:0007158) | 3.43442011 |
25 | regulation of microtubule-based movement (GO:0060632) | 3.36553796 |
26 | regulation of timing of cell differentiation (GO:0048505) | 3.35137696 |
27 | nonmotile primary cilium assembly (GO:0035058) | 3.31922869 |
28 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.29590902 |
29 | centriole assembly (GO:0098534) | 3.23748061 |
30 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.23561557 |
31 | protein polyglutamylation (GO:0018095) | 3.22437130 |
32 | glutamate receptor signaling pathway (GO:0007215) | 3.21859231 |
33 | L-fucose catabolic process (GO:0042355) | 3.20115431 |
34 | fucose catabolic process (GO:0019317) | 3.20115431 |
35 | L-fucose metabolic process (GO:0042354) | 3.20115431 |
36 | left/right pattern formation (GO:0060972) | 3.19418851 |
37 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.19067186 |
38 | response to pheromone (GO:0019236) | 3.17014985 |
39 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.16835582 |
40 | ventricular system development (GO:0021591) | 3.15080349 |
41 | base-excision repair, AP site formation (GO:0006285) | 3.12054360 |
42 | neural tube formation (GO:0001841) | 3.09656615 |
43 | neuronal action potential propagation (GO:0019227) | 3.09351747 |
44 | protein localization to cilium (GO:0061512) | 3.06400581 |
45 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.05579820 |
46 | sensory perception of smell (GO:0007608) | 3.04780572 |
47 | axon ensheathment in central nervous system (GO:0032291) | 3.03693673 |
48 | central nervous system myelination (GO:0022010) | 3.03693673 |
49 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.02847748 |
50 | sperm motility (GO:0030317) | 3.01961749 |
51 | DNA deamination (GO:0045006) | 3.01540453 |
52 | neuronal action potential (GO:0019228) | 3.01501607 |
53 | cellular ketone body metabolic process (GO:0046950) | 3.00043095 |
54 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.99421336 |
55 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.99263896 |
56 | cilium morphogenesis (GO:0060271) | 2.98761090 |
57 | calcium ion import (GO:0070509) | 2.98468196 |
58 | indolalkylamine metabolic process (GO:0006586) | 2.97879538 |
59 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 2.96681861 |
60 | retinal ganglion cell axon guidance (GO:0031290) | 2.96393433 |
61 | synaptic transmission, glutamatergic (GO:0035249) | 2.95566831 |
62 | pseudouridine synthesis (GO:0001522) | 2.94663553 |
63 | cellular response to ATP (GO:0071318) | 2.91093363 |
64 | response to auditory stimulus (GO:0010996) | 2.85729740 |
65 | cell projection assembly (GO:0030031) | 2.85184398 |
66 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.83973347 |
67 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.83908974 |
68 | photoreceptor cell maintenance (GO:0045494) | 2.83518172 |
69 | retina layer formation (GO:0010842) | 2.83516012 |
70 | UTP biosynthetic process (GO:0006228) | 2.83307992 |
71 | negative regulation of B cell mediated immunity (GO:0002713) | 2.83178850 |
72 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.83178850 |
73 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.82291607 |
74 | neuron-neuron synaptic transmission (GO:0007270) | 2.81606555 |
75 | limb bud formation (GO:0060174) | 2.80774696 |
76 | calcium ion-dependent exocytosis (GO:0017156) | 2.80730997 |
77 | tryptophan catabolic process (GO:0006569) | 2.80370128 |
78 | indole-containing compound catabolic process (GO:0042436) | 2.80370128 |
79 | indolalkylamine catabolic process (GO:0046218) | 2.80370128 |
80 | cellular component assembly involved in morphogenesis (GO:0010927) | 2.80206962 |
81 | vocalization behavior (GO:0071625) | 2.78929278 |
82 | gamma-aminobutyric acid transport (GO:0015812) | 2.78027573 |
83 | centriole replication (GO:0007099) | 2.77310357 |
84 | positive regulation of synapse assembly (GO:0051965) | 2.76767947 |
85 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.76692470 |
86 | smoothened signaling pathway (GO:0007224) | 2.76290060 |
87 | negative regulation of telomere maintenance (GO:0032205) | 2.76144489 |
88 | regulation of development, heterochronic (GO:0040034) | 2.74866645 |
89 | transmission of nerve impulse (GO:0019226) | 2.73401907 |
90 | neuronal ion channel clustering (GO:0045161) | 2.72175883 |
91 | dentate gyrus development (GO:0021542) | 2.71192174 |
92 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.70457978 |
93 | detection of light stimulus involved in visual perception (GO:0050908) | 2.70457978 |
94 | retinal cone cell development (GO:0046549) | 2.69935258 |
95 | peptidyl-histidine modification (GO:0018202) | 2.69745662 |
96 | microglial cell activation (GO:0001774) | 2.68181510 |
97 | spinal cord motor neuron differentiation (GO:0021522) | 2.67410990 |
98 | neuron recognition (GO:0008038) | 2.66820795 |
99 | eye photoreceptor cell differentiation (GO:0001754) | 2.66267374 |
100 | photoreceptor cell differentiation (GO:0046530) | 2.66267374 |
101 | exogenous drug catabolic process (GO:0042738) | 2.64404868 |
102 | protein complex biogenesis (GO:0070271) | 2.62990819 |
103 | G-protein coupled receptor internalization (GO:0002031) | 2.62904110 |
104 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 2.62633248 |
105 | tryptophan metabolic process (GO:0006568) | 2.62011278 |
106 | regulation of germinal center formation (GO:0002634) | 2.61189120 |
107 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.60522289 |
108 | ketone body metabolic process (GO:1902224) | 2.59653597 |
109 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.59595998 |
110 | NADH dehydrogenase complex assembly (GO:0010257) | 2.59595998 |
111 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.59595998 |
112 | nucleotide transmembrane transport (GO:1901679) | 2.59385777 |
113 | urinary tract smooth muscle contraction (GO:0014848) | 2.59172962 |
114 | kynurenine metabolic process (GO:0070189) | 2.59068573 |
115 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.58893326 |
116 | innervation (GO:0060384) | 2.58795343 |
117 | left/right axis specification (GO:0070986) | 2.58683623 |
118 | determination of left/right symmetry (GO:0007368) | 2.58195360 |
119 | reciprocal meiotic recombination (GO:0007131) | 2.58176146 |
120 | reciprocal DNA recombination (GO:0035825) | 2.58176146 |
121 | response to xenobiotic stimulus (GO:0009410) | 2.57520934 |
122 | regulation of pigment cell differentiation (GO:0050932) | 2.57430174 |
123 | axonal fasciculation (GO:0007413) | 2.57140035 |
124 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.55501540 |
125 | drug catabolic process (GO:0042737) | 2.55329314 |
126 | aldehyde catabolic process (GO:0046185) | 2.54562524 |
127 | cranial nerve morphogenesis (GO:0021602) | 2.54119793 |
128 | regulation of action potential (GO:0098900) | 2.53146894 |
129 | microtubule-based movement (GO:0007018) | 2.52843944 |
130 | multicellular organism reproduction (GO:0032504) | 2.52618512 |
131 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.50626395 |
132 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.50626395 |
133 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.50058297 |
134 | eye photoreceptor cell development (GO:0042462) | 2.49862129 |
135 | mechanosensory behavior (GO:0007638) | 2.49242392 |
136 | cranial nerve structural organization (GO:0021604) | 2.49201584 |
137 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.49154779 |
138 | UTP metabolic process (GO:0046051) | 2.48687372 |
139 | response to histamine (GO:0034776) | 2.48221917 |
140 | rRNA catabolic process (GO:0016075) | 2.47049579 |
141 | mannosylation (GO:0097502) | 2.46999242 |
142 | limb development (GO:0060173) | 2.46725046 |
143 | appendage development (GO:0048736) | 2.46725046 |
144 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.46687082 |
145 | photoreceptor cell development (GO:0042461) | 2.46489388 |
146 | protein localization to synapse (GO:0035418) | 2.46374330 |
147 | microtubule depolymerization (GO:0007019) | 2.44984905 |
148 | synaptic vesicle exocytosis (GO:0016079) | 2.44871343 |
149 | primary alcohol catabolic process (GO:0034310) | 2.44615677 |
150 | DNA methylation involved in gamete generation (GO:0043046) | 2.44258740 |
151 | respiratory chain complex IV assembly (GO:0008535) | 2.44170089 |
152 | membrane depolarization during action potential (GO:0086010) | 2.44060463 |
153 | long-term synaptic potentiation (GO:0060291) | 2.42043498 |
154 | glutamate secretion (GO:0014047) | 2.42009626 |
155 | polyketide metabolic process (GO:0030638) | 2.41691462 |
156 | doxorubicin metabolic process (GO:0044598) | 2.41691462 |
157 | daunorubicin metabolic process (GO:0044597) | 2.41691462 |
158 | positive regulation of action potential (GO:0045760) | 2.41409993 |
159 | neurotransmitter uptake (GO:0001504) | 2.41359299 |
160 | oligodendrocyte differentiation (GO:0048709) | 2.41273074 |
161 | regulation of collateral sprouting (GO:0048670) | 2.39617449 |
162 | determination of bilateral symmetry (GO:0009855) | 2.38837185 |
163 | auditory behavior (GO:0031223) | 2.37167934 |
164 | tRNA modification (GO:0006400) | 2.36617434 |
165 | sialylation (GO:0097503) | 2.36205634 |
166 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 2.35730907 |
167 | intra-S DNA damage checkpoint (GO:0031573) | 2.35670761 |
168 | meiotic chromosome segregation (GO:0045132) | 2.35640314 |
169 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.34590018 |
170 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.34590018 |
171 | piRNA metabolic process (GO:0034587) | 2.34362229 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.76173650 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.82927344 |
3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.41367469 |
4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.11071825 |
5 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.66993893 |
6 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.50709279 |
7 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.48779604 |
8 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.37324630 |
9 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.36715217 |
10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.31174166 |
11 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.28973537 |
12 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.27361381 |
13 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.24756691 |
14 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.24208750 |
15 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.16070947 |
16 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.14091953 |
17 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.13171200 |
18 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.11254765 |
19 | * CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 2.11254346 |
20 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.01819101 |
21 | VDR_22108803_ChIP-Seq_LS180_Human | 2.00538755 |
22 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.99394968 |
23 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.98544943 |
24 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.97889440 |
25 | P300_19829295_ChIP-Seq_ESCs_Human | 1.96527571 |
26 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.95556530 |
27 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.95014297 |
28 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.93522180 |
29 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.93507113 |
30 | EWS_26573619_Chip-Seq_HEK293_Human | 1.93441380 |
31 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.85474160 |
32 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.84735348 |
33 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.82217630 |
34 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.82217630 |
35 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.80530970 |
36 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.80076834 |
37 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.77866398 |
38 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.76982338 |
39 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.76151831 |
40 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.74639698 |
41 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.73504258 |
42 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.73373369 |
43 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.72699663 |
44 | FUS_26573619_Chip-Seq_HEK293_Human | 1.71533699 |
45 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.65716065 |
46 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.64723975 |
47 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.64688534 |
48 | ERA_21632823_ChIP-Seq_H3396_Human | 1.61753906 |
49 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.61180447 |
50 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.60653070 |
51 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.59468311 |
52 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.58563481 |
53 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.57212604 |
54 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.56658535 |
55 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.54288750 |
56 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.54275791 |
57 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.52041907 |
58 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.50670924 |
59 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.49704192 |
60 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.48890174 |
61 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.48259346 |
62 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.46822361 |
63 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.46616292 |
64 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.46179254 |
65 | NCOR_22424771_ChIP-Seq_293T_Human | 1.46041946 |
66 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.45562720 |
67 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.45023968 |
68 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.44186649 |
69 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.43873948 |
70 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.40888120 |
71 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.40812743 |
72 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.40261591 |
73 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.39460961 |
74 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.39158895 |
75 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.35526993 |
76 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.35498015 |
77 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.35498015 |
78 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.35097705 |
79 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.34628326 |
80 | * CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.34282792 |
81 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.33572871 |
82 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.32890763 |
83 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.32552394 |
84 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.32251789 |
85 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.30615547 |
86 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.30507121 |
87 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.30507121 |
88 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.30161640 |
89 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.30076359 |
90 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.29815977 |
91 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.29048757 |
92 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.27580773 |
93 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26380785 |
94 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.25790933 |
95 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.25731438 |
96 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.25651805 |
97 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.25395627 |
98 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.24680948 |
99 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.24221756 |
100 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.24055598 |
101 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.23927549 |
102 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.23354366 |
103 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.23351331 |
104 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.23071825 |
105 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.22695567 |
106 | * P300_18555785_Chip-Seq_ESCs_Mouse | 1.21587710 |
107 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.21146716 |
108 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.21130075 |
109 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.20754497 |
110 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.20295229 |
111 | * PHF8_20622854_ChIP-Seq_HELA_Human | 1.20130707 |
112 | AR_25329375_ChIP-Seq_VCAP_Human | 1.20001249 |
113 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.19667301 |
114 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.19584124 |
115 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.18424776 |
116 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.18424776 |
117 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.17611304 |
118 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.17329603 |
119 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.17050637 |
120 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.15863867 |
121 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.15619624 |
122 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.13854335 |
123 | * P53_21459846_ChIP-Seq_SAOS-2_Human | 1.13345650 |
124 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.13113692 |
125 | TCF4_23295773_ChIP-Seq_U87_Human | 1.12955279 |
126 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.12446446 |
127 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.12406635 |
128 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.11674469 |
129 | STAT3_23295773_ChIP-Seq_U87_Human | 1.11612800 |
130 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.11552651 |
131 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.11047436 |
132 | * P68_20966046_ChIP-Seq_HELA_Human | 1.10851797 |
133 | AR_20517297_ChIP-Seq_VCAP_Human | 1.10837080 |
134 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.10527483 |
135 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.10359960 |
136 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.10226422 |
137 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.10055741 |
138 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.09198466 |
139 | KDM2B_26808549_Chip-Seq_REH_Human | 1.08451910 |
140 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.07938817 |
141 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.07559149 |
142 | JUN_21703547_ChIP-Seq_K562_Human | 1.06938279 |
143 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.06179694 |
144 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.04452723 |
145 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.03965608 |
146 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.03845608 |
147 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.03740665 |
148 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.02934868 |
149 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.01569749 |
150 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.01490831 |
151 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.01469927 |
152 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.98802906 |
153 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.98530122 |
154 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.97858901 |
155 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.97836579 |
156 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97281504 |
157 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.96643465 |
158 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.95805247 |
159 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 0.95689322 |
160 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94890653 |
161 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 0.94408961 |
162 | * PHF8_20622853_ChIP-Seq_HELA_Human | 0.93402497 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0006292_abnormal_olfactory_placode | 3.53929895 |
2 | MP0008875_abnormal_xenobiotic_pharmacok | 3.53811883 |
3 | MP0002653_abnormal_ependyma_morphology | 3.39011666 |
4 | MP0001984_abnormal_olfaction | 3.16566247 |
5 | MP0004043_abnormal_pH_regulation | 2.89823203 |
6 | MP0005645_abnormal_hypothalamus_physiol | 2.78311720 |
7 | MP0003880_abnormal_central_pattern | 2.78307237 |
8 | MP0001188_hyperpigmentation | 2.75114518 |
9 | MP0005646_abnormal_pituitary_gland | 2.74288044 |
10 | MP0004859_abnormal_synaptic_plasticity | 2.64176524 |
11 | MP0009046_muscle_twitch | 2.52159796 |
12 | MP0005410_abnormal_fertilization | 2.23120116 |
13 | MP0005551_abnormal_eye_electrophysiolog | 2.17477324 |
14 | MP0002572_abnormal_emotion/affect_behav | 2.14938202 |
15 | MP0002736_abnormal_nociception_after | 2.13230945 |
16 | MP0001486_abnormal_startle_reflex | 2.11805092 |
17 | MP0002064_seizures | 2.10714246 |
18 | MP0003635_abnormal_synaptic_transmissio | 2.07936017 |
19 | MP0009745_abnormal_behavioral_response | 2.05459305 |
20 | MP0002272_abnormal_nervous_system | 2.03335049 |
21 | MP0002638_abnormal_pupillary_reflex | 1.96326607 |
22 | MP0002102_abnormal_ear_morphology | 1.94369515 |
23 | MP0002063_abnormal_learning/memory/cond | 1.92161935 |
24 | MP0000566_synostosis | 1.91496650 |
25 | MP0001968_abnormal_touch/_nociception | 1.89057265 |
26 | MP0003787_abnormal_imprinting | 1.84716976 |
27 | MP0005174_abnormal_tail_pigmentation | 1.83738453 |
28 | MP0002735_abnormal_chemical_nociception | 1.82992877 |
29 | MP0004142_abnormal_muscle_tone | 1.79095156 |
30 | MP0002067_abnormal_sensory_capabilities | 1.77743898 |
31 | MP0002557_abnormal_social/conspecific_i | 1.77670684 |
32 | MP0000778_abnormal_nervous_system | 1.75985120 |
33 | MP0004742_abnormal_vestibular_system | 1.74158864 |
34 | MP0003183_abnormal_peptide_metabolism | 1.73360693 |
35 | MP0001440_abnormal_grooming_behavior | 1.71142162 |
36 | MP0003136_yellow_coat_color | 1.66808040 |
37 | MP0003878_abnormal_ear_physiology | 1.63467056 |
38 | MP0005377_hearing/vestibular/ear_phenot | 1.63467056 |
39 | MP0005423_abnormal_somatic_nervous | 1.62705278 |
40 | MP0004133_heterotaxia | 1.62448008 |
41 | MP0008872_abnormal_physiological_respon | 1.61656143 |
42 | MP0005171_absent_coat_pigmentation | 1.61412730 |
43 | MP0001502_abnormal_circadian_rhythm | 1.61366791 |
44 | MP0003195_calcinosis | 1.57493882 |
45 | MP0000631_abnormal_neuroendocrine_gland | 1.55753752 |
46 | MP0002184_abnormal_innervation | 1.54777369 |
47 | MP0004147_increased_porphyrin_level | 1.53407172 |
48 | MP0002277_abnormal_respiratory_mucosa | 1.52673294 |
49 | MP0001986_abnormal_taste_sensitivity | 1.50259386 |
50 | MP0001905_abnormal_dopamine_level | 1.47998024 |
51 | MP0003879_abnormal_hair_cell | 1.47435973 |
52 | MP0005253_abnormal_eye_physiology | 1.47258591 |
53 | MP0002734_abnormal_mechanical_nocicepti | 1.46706833 |
54 | MP0000026_abnormal_inner_ear | 1.43340761 |
55 | MP0001501_abnormal_sleep_pattern | 1.42736950 |
56 | MP0002876_abnormal_thyroid_physiology | 1.39488218 |
57 | MP0008789_abnormal_olfactory_epithelium | 1.37508701 |
58 | MP0008877_abnormal_DNA_methylation | 1.36360091 |
59 | MP0005394_taste/olfaction_phenotype | 1.34432843 |
60 | MP0005499_abnormal_olfactory_system | 1.34432843 |
61 | MP0008004_abnormal_stomach_pH | 1.33654037 |
62 | MP0001529_abnormal_vocalization | 1.29137615 |
63 | MP0004270_analgesia | 1.28924813 |
64 | MP0005670_abnormal_white_adipose | 1.25313758 |
65 | MP0006276_abnormal_autonomic_nervous | 1.24516632 |
66 | MP0009379_abnormal_foot_pigmentation | 1.22705337 |
67 | MP0004885_abnormal_endolymph | 1.21572206 |
68 | MP0001963_abnormal_hearing_physiology | 1.21119220 |
69 | MP0006072_abnormal_retinal_apoptosis | 1.20729169 |
70 | MP0005083_abnormal_biliary_tract | 1.20441016 |
71 | MP0002928_abnormal_bile_duct | 1.19030441 |
72 | MP0000427_abnormal_hair_cycle | 1.19018337 |
73 | MP0003698_abnormal_male_reproductive | 1.18569746 |
74 | MP0002752_abnormal_somatic_nervous | 1.17378587 |
75 | MP0005379_endocrine/exocrine_gland_phen | 1.16747156 |
76 | MP0002938_white_spotting | 1.15935371 |
77 | MP0001485_abnormal_pinna_reflex | 1.12618480 |
78 | MP0005389_reproductive_system_phenotype | 1.11364833 |
79 | MP0000383_abnormal_hair_follicle | 1.11262275 |
80 | MP0003122_maternal_imprinting | 1.10889080 |
81 | MP0005195_abnormal_posterior_eye | 1.09630894 |
82 | MP0000372_irregular_coat_pigmentation | 1.09325657 |
83 | MP0008260_abnormal_autophagy | 1.08870609 |
84 | MP0002882_abnormal_neuron_morphology | 1.08657533 |
85 | MP0003938_abnormal_ear_development | 1.07934233 |
86 | MP0002837_dystrophic_cardiac_calcinosis | 1.05368358 |
87 | MP0008058_abnormal_DNA_repair | 1.03390943 |
88 | MP0002132_abnormal_respiratory_system | 1.01728537 |
89 | MP0003137_abnormal_impulse_conducting | 1.01069377 |
90 | MP0000681_abnormal_thyroid_gland | 0.99230275 |
91 | MP0001765_abnormal_ion_homeostasis | 0.98734607 |
92 | MP0002282_abnormal_trachea_morphology | 0.97581032 |
93 | MP0002909_abnormal_adrenal_gland | 0.97135217 |
94 | MP0001970_abnormal_pain_threshold | 0.97083673 |
95 | MP0003646_muscle_fatigue | 0.95916689 |
96 | MP0002229_neurodegeneration | 0.94706516 |
97 | MP0002249_abnormal_larynx_morphology | 0.93406225 |
98 | MP0002160_abnormal_reproductive_system | 0.91130205 |
99 | MP0003634_abnormal_glial_cell | 0.90310094 |
100 | MP0010386_abnormal_urinary_bladder | 0.89866441 |
101 | MP0005391_vision/eye_phenotype | 0.88954605 |
102 | MP0003011_delayed_dark_adaptation | 0.88053255 |
103 | MP0002066_abnormal_motor_capabilities/c | 0.87898757 |
104 | MP0004019_abnormal_vitamin_homeostasis | 0.86016600 |
105 | MP0002234_abnormal_pharynx_morphology | 0.85916610 |
106 | MP0001756_abnormal_urination | 0.85681494 |
107 | MP0003690_abnormal_glial_cell | 0.85529474 |
108 | MP0008995_early_reproductive_senescence | 0.85477412 |
109 | MP0002751_abnormal_autonomic_nervous | 0.85430547 |
110 | MP0000920_abnormal_myelination | 0.85249491 |
111 | MP0000955_abnormal_spinal_cord | 0.84087954 |
112 | MP0002152_abnormal_brain_morphology | 0.81775074 |
113 | MP0002168_other_aberrant_phenotype | 0.81634731 |
114 | MP0004924_abnormal_behavior | 0.80853748 |
115 | MP0005386_behavior/neurological_phenoty | 0.80853748 |
116 | MP0004145_abnormal_muscle_electrophysio | 0.80649338 |
117 | MP0002090_abnormal_vision | 0.79770792 |
118 | MP0002733_abnormal_thermal_nociception | 0.79182631 |
119 | MP0003718_maternal_effect | 0.78879357 |
120 | MP0001929_abnormal_gametogenesis | 0.78843634 |
121 | MP0000049_abnormal_middle_ear | 0.78647399 |
122 | MP0009780_abnormal_chondrocyte_physiolo | 0.78559442 |
123 | MP0008961_abnormal_basal_metabolism | 0.77929125 |
124 | MP0004134_abnormal_chest_morphology | 0.77085913 |
125 | MP0001293_anophthalmia | 0.77028755 |
126 | MP0004510_myositis | 0.76626948 |
127 | MP0005409_darkened_coat_color | 0.76526783 |
128 | MP0001324_abnormal_eye_pigmentation | 0.76476945 |
129 | MP0000538_abnormal_urinary_bladder | 0.75505285 |
130 | MP0002210_abnormal_sex_determination | 0.75203419 |
131 | MP0001346_abnormal_lacrimal_gland | 0.73895821 |
132 | MP0005248_abnormal_Harderian_gland | 0.71438660 |
133 | MP0001664_abnormal_digestion | 0.70710823 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 6.43528229 |
2 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.43453414 |
3 | Absent/shortened dynein arms (HP:0200106) | 6.43453414 |
4 | Abnormal ciliary motility (HP:0012262) | 6.26305886 |
5 | Abnormal respiratory motile cilium physiology (HP:0012261) | 6.08681414 |
6 | Abnormal respiratory epithelium morphology (HP:0012253) | 6.00533158 |
7 | Abnormal respiratory motile cilium morphology (HP:0005938) | 6.00533158 |
8 | Rhinitis (HP:0012384) | 5.15114072 |
9 | Pancreatic fibrosis (HP:0100732) | 4.17064643 |
10 | True hermaphroditism (HP:0010459) | 3.92184491 |
11 | Medial flaring of the eyebrow (HP:0010747) | 3.88791373 |
12 | Gait imbalance (HP:0002141) | 3.59997002 |
13 | Febrile seizures (HP:0002373) | 3.52209152 |
14 | Nephrogenic diabetes insipidus (HP:0009806) | 3.51841873 |
15 | Congenital primary aphakia (HP:0007707) | 3.50778813 |
16 | Epileptic encephalopathy (HP:0200134) | 3.35762083 |
17 | Nasal polyposis (HP:0100582) | 3.23448819 |
18 | Molar tooth sign on MRI (HP:0002419) | 3.21559515 |
19 | Abnormality of midbrain morphology (HP:0002418) | 3.21559515 |
20 | Chronic bronchitis (HP:0004469) | 3.07964824 |
21 | Tubular atrophy (HP:0000092) | 3.07187248 |
22 | Septo-optic dysplasia (HP:0100842) | 3.04148301 |
23 | Nephronophthisis (HP:0000090) | 3.00597434 |
24 | Tubulointerstitial nephritis (HP:0001970) | 2.99246415 |
25 | Focal motor seizures (HP:0011153) | 2.86464850 |
26 | Bronchiectasis (HP:0002110) | 2.77504152 |
27 | Pancreatic cysts (HP:0001737) | 2.76540096 |
28 | Decreased central vision (HP:0007663) | 2.74868572 |
29 | Atonic seizures (HP:0010819) | 2.69353200 |
30 | Abnormality of the renal medulla (HP:0100957) | 2.63619773 |
31 | Genital tract atresia (HP:0001827) | 2.62760072 |
32 | Aplasia/Hypoplasia of the lens (HP:0008063) | 2.59309405 |
33 | Vaginal atresia (HP:0000148) | 2.57882231 |
34 | Attenuation of retinal blood vessels (HP:0007843) | 2.52805832 |
35 | Occipital encephalocele (HP:0002085) | 2.52725389 |
36 | Abnormality of the renal cortex (HP:0011035) | 2.52682769 |
37 | Infertility (HP:0000789) | 2.50289385 |
38 | Decreased circulating renin level (HP:0003351) | 2.48334208 |
39 | Hyperventilation (HP:0002883) | 2.48017055 |
40 | Hypothermia (HP:0002045) | 2.42264458 |
41 | Poor coordination (HP:0002370) | 2.39127130 |
42 | Type II lissencephaly (HP:0007260) | 2.38553970 |
43 | Congenital hepatic fibrosis (HP:0002612) | 2.38111057 |
44 | Abnormal hair whorl (HP:0010721) | 2.36752422 |
45 | Retinal dysplasia (HP:0007973) | 2.36568289 |
46 | Chronic hepatic failure (HP:0100626) | 2.36042457 |
47 | Abnormality of the nasal mucosa (HP:0000433) | 2.35817437 |
48 | Chronic sinusitis (HP:0011109) | 2.35309276 |
49 | Median cleft lip (HP:0000161) | 2.32333140 |
50 | Postaxial foot polydactyly (HP:0001830) | 2.23322168 |
51 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.22774892 |
52 | Recurrent sinusitis (HP:0011108) | 2.21201412 |
53 | Abolished electroretinogram (ERG) (HP:0000550) | 2.21018786 |
54 | Pendular nystagmus (HP:0012043) | 2.20676317 |
55 | Chronic otitis media (HP:0000389) | 2.20191472 |
56 | Preaxial hand polydactyly (HP:0001177) | 2.18986042 |
57 | Rib fusion (HP:0000902) | 2.16066677 |
58 | Hyperphosphatemia (HP:0002905) | 2.14267681 |
59 | Polyuria (HP:0000103) | 2.13963712 |
60 | Bronchitis (HP:0012387) | 2.12298832 |
61 | Optic nerve hypoplasia (HP:0000609) | 2.11455605 |
62 | Cerebellar dysplasia (HP:0007033) | 2.11108150 |
63 | Asplenia (HP:0001746) | 2.10145485 |
64 | Genetic anticipation (HP:0003743) | 2.07887368 |
65 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.05272242 |
66 | Furrowed tongue (HP:0000221) | 2.03375675 |
67 | Thyroid-stimulating hormone excess (HP:0002925) | 2.03297854 |
68 | Abnormality of incisor morphology (HP:0011063) | 2.00195245 |
69 | Postaxial hand polydactyly (HP:0001162) | 2.00017790 |
70 | Abnormality of macular pigmentation (HP:0008002) | 1.99176982 |
71 | Polyphagia (HP:0002591) | 1.97859707 |
72 | Male infertility (HP:0003251) | 1.95955112 |
73 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.94429785 |
74 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.93833904 |
75 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.91766274 |
76 | Cystic liver disease (HP:0006706) | 1.91511528 |
77 | Fair hair (HP:0002286) | 1.90390093 |
78 | Retinitis pigmentosa (HP:0000510) | 1.90305334 |
79 | Anencephaly (HP:0002323) | 1.89692330 |
80 | Congenital stationary night blindness (HP:0007642) | 1.89677167 |
81 | Polydipsia (HP:0001959) | 1.89491431 |
82 | Abnormal drinking behavior (HP:0030082) | 1.89491431 |
83 | J-shaped sella turcica (HP:0002680) | 1.89376374 |
84 | 3-Methylglutaconic aciduria (HP:0003535) | 1.89213346 |
85 | Inability to walk (HP:0002540) | 1.87249317 |
86 | Atelectasis (HP:0100750) | 1.86360027 |
87 | Gaze-evoked nystagmus (HP:0000640) | 1.86041256 |
88 | Aganglionic megacolon (HP:0002251) | 1.85754981 |
89 | Patellar aplasia (HP:0006443) | 1.85734841 |
90 | Chorioretinal atrophy (HP:0000533) | 1.85301394 |
91 | Acute necrotizing encephalopathy (HP:0006965) | 1.83417591 |
92 | Microvesicular hepatic steatosis (HP:0001414) | 1.83343188 |
93 | Abnormal biliary tract physiology (HP:0012439) | 1.83331727 |
94 | Bile duct proliferation (HP:0001408) | 1.83331727 |
95 | Oculomotor apraxia (HP:0000657) | 1.82284564 |
96 | Progressive cerebellar ataxia (HP:0002073) | 1.81315393 |
97 | Abnormality of renal resorption (HP:0011038) | 1.81142547 |
98 | Parakeratosis (HP:0001036) | 1.80442766 |
99 | Supernumerary spleens (HP:0009799) | 1.79463373 |
100 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.75903061 |
101 | Hypoplasia of the pons (HP:0012110) | 1.75528924 |
102 | Aplasia cutis congenita (HP:0001057) | 1.74690186 |
103 | Submucous cleft hard palate (HP:0000176) | 1.73381406 |
104 | Methylmalonic acidemia (HP:0002912) | 1.73127060 |
105 | Renal Fanconi syndrome (HP:0001994) | 1.71777017 |
106 | Sclerocornea (HP:0000647) | 1.71448880 |
107 | Male pseudohermaphroditism (HP:0000037) | 1.71155447 |
108 | Abnormality of the pons (HP:0007361) | 1.69346081 |
109 | White forelock (HP:0002211) | 1.69136648 |
110 | Astigmatism (HP:0000483) | 1.68604516 |
111 | Optic disc pallor (HP:0000543) | 1.68566820 |
112 | Progressive macrocephaly (HP:0004481) | 1.67955515 |
113 | Focal seizures (HP:0007359) | 1.67879537 |
114 | Methylmalonic aciduria (HP:0012120) | 1.65338779 |
115 | Recurrent otitis media (HP:0000403) | 1.63280539 |
116 | Absence seizures (HP:0002121) | 1.62484725 |
117 | Absent septum pellucidum (HP:0001331) | 1.62326087 |
118 | Tubulointerstitial abnormality (HP:0001969) | 1.61912939 |
119 | Broad-based gait (HP:0002136) | 1.61807160 |
120 | Abnormality of renin-angiotensin system (HP:0000847) | 1.61724436 |
121 | Chorioretinal coloboma (HP:0000567) | 1.61679360 |
122 | Anophthalmia (HP:0000528) | 1.61148920 |
123 | Large for gestational age (HP:0001520) | 1.61026377 |
124 | Dialeptic seizures (HP:0011146) | 1.60943991 |
125 | Abnormal urine output (HP:0012590) | 1.58844740 |
126 | Nephropathy (HP:0000112) | 1.58555475 |
127 | Stage 5 chronic kidney disease (HP:0003774) | 1.58507323 |
128 | Hepatocellular necrosis (HP:0001404) | 1.58211197 |
129 | Lissencephaly (HP:0001339) | 1.56734543 |
130 | Severe visual impairment (HP:0001141) | 1.56386247 |
131 | Abnormality of the septum pellucidum (HP:0007375) | 1.56300574 |
132 | Broad foot (HP:0001769) | 1.56050515 |
133 | Cerebral palsy (HP:0100021) | 1.55918549 |
134 | Absent speech (HP:0001344) | 1.55413036 |
135 | Abnormality of renal excretion (HP:0011036) | 1.53577277 |
136 | Hyperactive renin-angiotensin system (HP:0000841) | 1.52087298 |
137 | Hyperglycinuria (HP:0003108) | 1.50029505 |
138 | Testicular atrophy (HP:0000029) | 1.48170045 |
139 | Mitochondrial inheritance (HP:0001427) | 1.48029466 |
140 | Multicystic kidney dysplasia (HP:0000003) | 1.46861185 |
141 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.45824209 |
142 | Hemiparesis (HP:0001269) | 1.43636050 |
143 | Absent thumb (HP:0009777) | 1.42718635 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CASK | 4.88971661 |
2 | FRK | 4.29622283 |
3 | MAPK15 | 3.86262447 |
4 | TNIK | 3.72622674 |
5 | TLK1 | 3.59684736 |
6 | SIK3 | 2.81369634 |
7 | MAP4K2 | 2.62218348 |
8 | AKT3 | 2.55785355 |
9 | ZAK | 2.54090195 |
10 | PRPF4B | 2.30862155 |
11 | STK16 | 2.29754927 |
12 | MAP2K7 | 2.23126732 |
13 | MKNK2 | 2.05003073 |
14 | NTRK2 | 2.00652549 |
15 | BLK | 1.98439897 |
16 | CDK19 | 1.94275638 |
17 | TAOK3 | 1.89899686 |
18 | MAPKAPK3 | 1.73344715 |
19 | NTRK3 | 1.67948389 |
20 | BMPR1B | 1.66290059 |
21 | ADRBK2 | 1.65994585 |
22 | IRAK1 | 1.65448759 |
23 | MAPK13 | 1.64867569 |
24 | ACVR1B | 1.48967114 |
25 | EPHA4 | 1.48261253 |
26 | IRAK2 | 1.47884698 |
27 | BCKDK | 1.47129455 |
28 | MUSK | 1.43834903 |
29 | GRK1 | 1.43118638 |
30 | PINK1 | 1.43078494 |
31 | WNK3 | 1.42289861 |
32 | NEK6 | 1.35646055 |
33 | CDK8 | 1.31931827 |
34 | STK39 | 1.29381500 |
35 | OXSR1 | 1.28458749 |
36 | MKNK1 | 1.27636941 |
37 | INSRR | 1.26412305 |
38 | MAP2K6 | 1.24164921 |
39 | BCR | 1.23587750 |
40 | DAPK2 | 1.23235725 |
41 | PLK2 | 1.21976391 |
42 | NEK2 | 1.17490841 |
43 | VRK2 | 1.15320059 |
44 | YES1 | 1.13215698 |
45 | GRK7 | 1.12971880 |
46 | MARK1 | 1.05848755 |
47 | MAP3K4 | 1.01865244 |
48 | PNCK | 1.00537715 |
49 | CDK3 | 1.00373679 |
50 | SGK494 | 0.97960851 |
51 | SGK223 | 0.97960851 |
52 | PKN1 | 0.97924500 |
53 | EPHA2 | 0.97211098 |
54 | BRD4 | 0.96126208 |
55 | SGK2 | 0.93108745 |
56 | DYRK1A | 0.92747024 |
57 | TSSK6 | 0.91493343 |
58 | TXK | 0.87004170 |
59 | BRAF | 0.85513809 |
60 | IRAK4 | 0.83811820 |
61 | CAMK1D | 0.83306754 |
62 | PRKCG | 0.82778791 |
63 | PRKCE | 0.82270205 |
64 | CAMKK2 | 0.81640712 |
65 | PAK3 | 0.81503771 |
66 | SIK2 | 0.79211889 |
67 | NME1 | 0.78841786 |
68 | DAPK1 | 0.78187308 |
69 | PHKG2 | 0.76235997 |
70 | PHKG1 | 0.76235997 |
71 | TNK2 | 0.76155760 |
72 | ATR | 0.74843358 |
73 | CAMKK1 | 0.74463062 |
74 | IRAK3 | 0.74143118 |
75 | CAMK1G | 0.73602076 |
76 | CAMK2A | 0.71975551 |
77 | MST4 | 0.71776642 |
78 | TRIM28 | 0.71696561 |
79 | RPS6KA5 | 0.71512487 |
80 | MAP3K7 | 0.70106877 |
81 | WNK1 | 0.69921844 |
82 | KSR1 | 0.69568542 |
83 | MAPKAPK5 | 0.68948728 |
84 | NUAK1 | 0.68296521 |
85 | CHEK2 | 0.67937972 |
86 | FES | 0.65989607 |
87 | BRSK2 | 0.65021991 |
88 | BMPR2 | 0.63414912 |
89 | MARK2 | 0.62882724 |
90 | ADRBK1 | 0.62550368 |
91 | TGFBR1 | 0.61876380 |
92 | WNK4 | 0.60260915 |
93 | CAMK2B | 0.58544553 |
94 | CSF1R | 0.57946929 |
95 | CAMK1 | 0.56259736 |
96 | CDK5 | 0.56043837 |
97 | ARAF | 0.55184529 |
98 | ICK | 0.53362105 |
99 | PRKAA1 | 0.53258478 |
100 | PRKD3 | 0.53050512 |
101 | DYRK2 | 0.52079017 |
102 | CHUK | 0.52011943 |
103 | TAF1 | 0.51923820 |
104 | FGR | 0.50835616 |
105 | PRKCH | 0.49726685 |
106 | CSNK1G3 | 0.49186278 |
107 | MAP3K12 | 0.48794392 |
108 | CAMK2D | 0.48656466 |
109 | ERBB3 | 0.48224529 |
110 | SYK | 0.47480417 |
111 | PLK1 | 0.46492359 |
112 | MINK1 | 0.46415013 |
113 | MAPK7 | 0.46014536 |
114 | RPS6KA6 | 0.45605923 |
115 | GRK5 | 0.45427922 |
116 | ERBB2 | 0.45398331 |
117 | LATS1 | 0.45159149 |
118 | PBK | 0.44988910 |
119 | PRKG1 | 0.43968550 |
120 | CAMK4 | 0.43748661 |
121 | PRKACA | 0.42649464 |
122 | TEC | 0.41960819 |
123 | STK11 | 0.41677187 |
124 | CSNK1A1 | 0.41152370 |
125 | MAPK12 | 0.41131652 |
126 | WEE1 | 0.40912572 |
127 | UHMK1 | 0.40396725 |
128 | PRKCQ | 0.39542508 |
129 | LYN | 0.39384342 |
130 | PRKAA2 | 0.39383434 |
131 | VRK1 | 0.38292421 |
132 | CSNK1G2 | 0.38210310 |
133 | CCNB1 | 0.38099698 |
134 | PRKCZ | 0.37883007 |
135 | EIF2AK3 | 0.37826324 |
136 | PTK2B | 0.37465656 |
137 | CSNK1G1 | 0.33879686 |
138 | RPS6KA2 | 0.33649467 |
139 | MELK | 0.32414387 |
140 | AURKA | 0.31658841 |
141 | PIM2 | 0.31397708 |
142 | ROCK2 | 0.31001748 |
143 | PRKCI | 0.29953508 |
144 | CSNK1A1L | 0.29215039 |
145 | DYRK3 | 0.29178824 |
146 | KIT | 0.28250129 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 4.20159767 |
2 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 3.01731058 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.82253156 |
4 | Olfactory transduction_Homo sapiens_hsa04740 | 2.65657636 |
5 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.58154169 |
6 | Phototransduction_Homo sapiens_hsa04744 | 2.57047484 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 2.45045241 |
8 | Taste transduction_Homo sapiens_hsa04742 | 2.43418125 |
9 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.42964569 |
10 | Morphine addiction_Homo sapiens_hsa05032 | 2.39695418 |
11 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.30013860 |
12 | Serotonergic synapse_Homo sapiens_hsa04726 | 2.26740994 |
13 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.22080287 |
14 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.21020843 |
15 | Circadian entrainment_Homo sapiens_hsa04713 | 2.15190146 |
16 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.10921083 |
17 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 2.00205185 |
18 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.94857403 |
19 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.93414004 |
20 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.87234063 |
21 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.86524044 |
22 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.77661446 |
23 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.77258545 |
24 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.73172586 |
25 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.68224327 |
26 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.59192930 |
27 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.58599850 |
28 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.57796715 |
29 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.52023747 |
30 | Protein export_Homo sapiens_hsa03060 | 1.50449780 |
31 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.48576167 |
32 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.47437473 |
33 | Insulin secretion_Homo sapiens_hsa04911 | 1.45984694 |
34 | Peroxisome_Homo sapiens_hsa04146 | 1.44037659 |
35 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.43053763 |
36 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.42735094 |
37 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.42141619 |
38 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.37762367 |
39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.37337580 |
40 | Sulfur relay system_Homo sapiens_hsa04122 | 1.33553930 |
41 | Huntingtons disease_Homo sapiens_hsa05016 | 1.33275483 |
42 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.32926450 |
43 | ABC transporters_Homo sapiens_hsa02010 | 1.31448383 |
44 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.25703671 |
45 | Alzheimers disease_Homo sapiens_hsa05010 | 1.20983348 |
46 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.13845893 |
47 | Salivary secretion_Homo sapiens_hsa04970 | 1.12866009 |
48 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.12671048 |
49 | Parkinsons disease_Homo sapiens_hsa05012 | 1.12512695 |
50 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.11368475 |
51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.11114753 |
52 | Axon guidance_Homo sapiens_hsa04360 | 1.10057836 |
53 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.09205528 |
54 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.05969717 |
55 | Long-term potentiation_Homo sapiens_hsa04720 | 1.05441003 |
56 | Circadian rhythm_Homo sapiens_hsa04710 | 1.05317196 |
57 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.03573346 |
58 | Phagosome_Homo sapiens_hsa04145 | 1.03277881 |
59 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.02430857 |
60 | Cocaine addiction_Homo sapiens_hsa05030 | 1.01893610 |
61 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.94140154 |
62 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.93532880 |
63 | Renin secretion_Homo sapiens_hsa04924 | 0.93329751 |
64 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.93148763 |
65 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.92884292 |
66 | Purine metabolism_Homo sapiens_hsa00230 | 0.90567950 |
67 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.88775336 |
68 | RNA degradation_Homo sapiens_hsa03018 | 0.88587171 |
69 | Other glycan degradation_Homo sapiens_hsa00511 | 0.86388867 |
70 | Long-term depression_Homo sapiens_hsa04730 | 0.83000281 |
71 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.82565473 |
72 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.81968118 |
73 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.79004770 |
74 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.76175795 |
75 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.70433598 |
76 | Basal transcription factors_Homo sapiens_hsa03022 | 0.70318858 |
77 | Base excision repair_Homo sapiens_hsa03410 | 0.69272239 |
78 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.69137590 |
79 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.69134668 |
80 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.68188061 |
81 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.67180772 |
82 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.67161739 |
83 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.67137835 |
84 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.66606707 |
85 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.66324900 |
86 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.64313321 |
87 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.62842024 |
88 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.62637161 |
89 | Lysine degradation_Homo sapiens_hsa00310 | 0.61967669 |
90 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.61166757 |
91 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.60857048 |
92 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.59581954 |
93 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.59021632 |
94 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.58834541 |
95 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.55519917 |
96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.55422150 |
97 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.54642873 |
98 | Allograft rejection_Homo sapiens_hsa05330 | 0.53838176 |
99 | RNA polymerase_Homo sapiens_hsa03020 | 0.53829192 |
100 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.53271133 |
101 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.52833860 |
102 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.51282022 |
103 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.50691298 |
104 | Alcoholism_Homo sapiens_hsa05034 | 0.50565012 |
105 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.47966126 |
106 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.47270232 |
107 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.42573095 |
108 | Metabolic pathways_Homo sapiens_hsa01100 | 0.42329882 |
109 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.41701859 |
110 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.41345100 |
111 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.41113344 |
112 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.41034986 |
113 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.40842180 |
114 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.40497843 |
115 | Histidine metabolism_Homo sapiens_hsa00340 | 0.40111609 |
116 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.39520790 |
117 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.37417477 |
118 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.36211751 |
119 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.35226595 |
120 | Homologous recombination_Homo sapiens_hsa03440 | 0.34920695 |
121 | Lysosome_Homo sapiens_hsa04142 | 0.34383140 |
122 | Asthma_Homo sapiens_hsa05310 | 0.33464883 |
123 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.33147085 |
124 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.32945521 |
125 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.32630599 |
126 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.32502774 |
127 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.31692269 |
128 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.30235397 |
129 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.30112564 |
130 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.28762523 |
131 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.28605282 |
132 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.28243471 |
133 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.27347710 |
134 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.26124949 |
135 | Melanoma_Homo sapiens_hsa05218 | 0.25359103 |
136 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.23564227 |
137 | Retinol metabolism_Homo sapiens_hsa00830 | 0.21947017 |
138 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.21390189 |
139 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.20648896 |
140 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.20548492 |