MORN3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)9.92159554
2plasma membrane fusion (GO:0045026)9.92065509
3cell-cell recognition (GO:0009988)9.70254342
4binding of sperm to zona pellucida (GO:0007339)9.56120489
5motile cilium assembly (GO:0044458)9.46768755
6reproduction (GO:0000003)9.19131917
7spermatid development (GO:0007286)9.11548207
8cilium movement (GO:0003341)8.60152804
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.54641369
10regulation of cilium movement (GO:0003352)8.22334291
11single fertilization (GO:0007338)7.10982704
12sperm capacitation (GO:0048240)6.79830735
13male meiosis (GO:0007140)6.50196991
14organic cation transport (GO:0015695)6.47097129
15synaptonemal complex organization (GO:0070193)6.38451897
16synaptonemal complex assembly (GO:0007130)6.29454429
17negative regulation of inclusion body assembly (GO:0090084)6.25282140
18spermatogenesis (GO:0007283)6.05151988
19male gamete generation (GO:0048232)6.02588830
20piRNA metabolic process (GO:0034587)6.00600060
21microtubule depolymerization (GO:0007019)5.91660635
22fertilization (GO:0009566)5.78163414
23gamete generation (GO:0007276)5.54271064
24ventricular system development (GO:0021591)5.38346425
25behavioral response to nicotine (GO:0035095)5.37802281
26spermatid nucleus differentiation (GO:0007289)5.16578573
27germ cell development (GO:0007281)4.99748903
28calcium ion-dependent exocytosis (GO:0017156)4.98248423
29cellular process involved in reproduction in multicellular organism (GO:0022412)4.91854988
30regulation of inclusion body assembly (GO:0090083)4.87364813
31L-fucose catabolic process (GO:0042355)4.82080971
32fucose catabolic process (GO:0019317)4.82080971
33L-fucose metabolic process (GO:0042354)4.82080971
34chromosome organization involved in meiosis (GO:0070192)4.74540764
35glycerol ether metabolic process (GO:0006662)4.72725255
36cell recognition (GO:0008037)4.58423516
37regulation of microtubule-based movement (GO:0060632)4.49376352
38male meiosis I (GO:0007141)4.37086574
39multicellular organismal reproductive process (GO:0048609)4.36596036
40ether metabolic process (GO:0018904)4.35699292
41chromosome condensation (GO:0030261)4.33256399
42DNA packaging (GO:0006323)4.13518221
43DNA deamination (GO:0045006)4.11609988
44response to pheromone (GO:0019236)4.02271168
45cellular ketone body metabolic process (GO:0046950)3.94081020
46left/right pattern formation (GO:0060972)3.87043106
47DNA methylation involved in gamete generation (GO:0043046)3.83143931
48seminiferous tubule development (GO:0072520)3.82780952
49meiotic nuclear division (GO:0007126)3.76473146
50centriole assembly (GO:0098534)3.73198132
51protein localization to cilium (GO:0061512)3.69665550
52sexual reproduction (GO:0019953)3.64675912
53axoneme assembly (GO:0035082)3.57436783
54single strand break repair (GO:0000012)3.53072113
55ketone body metabolic process (GO:1902224)3.52683120
56multicellular organismal development (GO:0007275)3.52244217
57meiosis I (GO:0007127)3.51933089
58synapsis (GO:0007129)3.51911435
59indole-containing compound catabolic process (GO:0042436)3.47682827
60indolalkylamine catabolic process (GO:0046218)3.47682827
61tryptophan catabolic process (GO:0006569)3.47682827
62microtubule severing (GO:0051013)3.46909073
63kynurenine metabolic process (GO:0070189)3.44326164
64amino-acid betaine transport (GO:0015838)3.43728519
65carnitine transport (GO:0015879)3.43728519
66genitalia morphogenesis (GO:0035112)3.43457605
67carnitine transmembrane transport (GO:1902603)3.38612937
68indolalkylamine metabolic process (GO:0006586)3.37238658
69protein K11-linked deubiquitination (GO:0035871)3.33853655
70detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.33601514
71centriole replication (GO:0007099)3.31893286
72water-soluble vitamin biosynthetic process (GO:0042364)3.28708148
73meiotic cell cycle (GO:0051321)3.27894438
74detection of light stimulus involved in sensory perception (GO:0050962)3.18415726
75detection of light stimulus involved in visual perception (GO:0050908)3.18415726
76GTP biosynthetic process (GO:0006183)3.14976458
77nucleoside diphosphate phosphorylation (GO:0006165)3.14661609
78nonmotile primary cilium assembly (GO:0035058)3.13920262
79cilium organization (GO:0044782)3.12093123
80sequestering of actin monomers (GO:0042989)3.11512963
81sulfation (GO:0051923)3.09047468
82cilium assembly (GO:0042384)3.04172989
83microtubule polymerization or depolymerization (GO:0031109)3.02874300
84tryptophan metabolic process (GO:0006568)3.01390280
85regulation of spindle checkpoint (GO:0090231)3.01000683
86cornea development in camera-type eye (GO:0061303)2.98448810
87respiratory chain complex IV assembly (GO:0008535)2.97311126
88chaperone-mediated protein complex assembly (GO:0051131)2.96235260
89negative regulation of mast cell activation (GO:0033004)2.95344453
90regulation of action potential (GO:0098900)2.93337201
91nucleus organization (GO:0006997)2.91762824
92negative regulation of telomere maintenance (GO:0032205)2.90465098
93rRNA catabolic process (GO:0016075)2.89555052
94protein complex biogenesis (GO:0070271)2.89204040
95neural tube formation (GO:0001841)2.86433376
96protein polyglutamylation (GO:0018095)2.86188188
97cilium morphogenesis (GO:0060271)2.85078000
98cellular component assembly involved in morphogenesis (GO:0010927)2.84645788
99negative regulation of synaptic transmission, GABAergic (GO:0032229)2.83776645
100preassembly of GPI anchor in ER membrane (GO:0016254)2.82382688
101monoubiquitinated protein deubiquitination (GO:0035520)2.80258968
102mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.79067091
103mitochondrial respiratory chain complex I assembly (GO:0032981)2.79067091
104NADH dehydrogenase complex assembly (GO:0010257)2.79067091
105kidney morphogenesis (GO:0060993)2.76231132
106platelet dense granule organization (GO:0060155)2.76171648
107photoreceptor cell maintenance (GO:0045494)2.75678716
108neuronal action potential (GO:0019228)2.75309624
109interferon-gamma secretion (GO:0072643)2.73542252
110RNA destabilization (GO:0050779)2.73433937
111cAMP catabolic process (GO:0006198)2.70977948
112intraciliary transport (GO:0042073)2.69884787
113UTP biosynthetic process (GO:0006228)2.69654826
114positive regulation of macrophage activation (GO:0043032)2.69307909
115cellular response to ATP (GO:0071318)2.67658520
116fucosylation (GO:0036065)2.67341376
117retinal cone cell development (GO:0046549)2.66099456
118mitotic sister chromatid cohesion (GO:0007064)2.65769030
119cytochrome complex assembly (GO:0017004)2.65219527
120mitochondrial respiratory chain complex assembly (GO:0033108)2.64335635
121meiotic cell cycle process (GO:1903046)2.63229923
122nephron epithelium morphogenesis (GO:0072088)2.63192530
123nephron tubule morphogenesis (GO:0072078)2.63192530
124regulation of podosome assembly (GO:0071801)2.62586015
125negative regulation of cytosolic calcium ion concentration (GO:0051481)2.62212344
126spinal cord motor neuron differentiation (GO:0021522)2.60520540
127quaternary ammonium group transport (GO:0015697)2.59867787
128indole-containing compound metabolic process (GO:0042430)2.58886972
129polyamine biosynthetic process (GO:0006596)2.58579565
130negative regulation of T cell differentiation in thymus (GO:0033085)2.58391488
131ubiquinone biosynthetic process (GO:0006744)2.57254215
132behavioral response to ethanol (GO:0048149)2.56177798
133regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.54603120
134single-organism membrane fusion (GO:0044801)2.54156878
135protein refolding (GO:0042026)2.52892953
136regulation of glucokinase activity (GO:0033131)2.52831602
137regulation of hexokinase activity (GO:1903299)2.52831602
138exogenous drug catabolic process (GO:0042738)2.52094376
139protein-cofactor linkage (GO:0018065)2.51670689
140adaptation of signaling pathway (GO:0023058)2.51547831
141reflex (GO:0060004)2.51481564
142synaptic transmission, cholinergic (GO:0007271)2.50575146
143photoreceptor cell development (GO:0042461)2.48543124
144microtubule-based movement (GO:0007018)2.47119570
145nuclear pore complex assembly (GO:0051292)2.46085040
146regulation of mesoderm development (GO:2000380)2.45689045
147left/right axis specification (GO:0070986)2.45521068
148regulation of centriole replication (GO:0046599)2.44921538
149sister chromatid cohesion (GO:0007062)2.44408888
150microtubule bundle formation (GO:0001578)2.44312701
151primary amino compound metabolic process (GO:1901160)2.44039559
152cyclic nucleotide catabolic process (GO:0009214)2.42192106
153negative regulation of reactive oxygen species metabolic process (GO:2000378)2.40685901
154regulation of rhodopsin mediated signaling pathway (GO:0022400)2.39172103
155gamma-aminobutyric acid transport (GO:0015812)2.38886534
156amine catabolic process (GO:0009310)2.38757309
157cellular biogenic amine catabolic process (GO:0042402)2.38757309
158drug catabolic process (GO:0042737)2.38567181
159positive regulation of fatty acid transport (GO:2000193)2.38406333
160G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.37775608
161regulation of neurotransmitter uptake (GO:0051580)2.37395552
162startle response (GO:0001964)2.36598093
163reciprocal DNA recombination (GO:0035825)2.36131607
164reciprocal meiotic recombination (GO:0007131)2.36131607
165rhodopsin mediated signaling pathway (GO:0016056)2.35798436
166GPI anchor metabolic process (GO:0006505)2.35213044
167polyol catabolic process (GO:0046174)2.34840785
168cell wall macromolecule metabolic process (GO:0044036)13.8872463
169cell wall macromolecule catabolic process (GO:0016998)13.8872463
170fusion of sperm to egg plasma membrane (GO:0007342)13.0484351
171sperm motility (GO:0030317)12.6317951
172acrosome reaction (GO:0007340)11.3552130
173sperm-egg recognition (GO:0035036)10.8375183
174multicellular organism reproduction (GO:0032504)10.7754791
175acrosome assembly (GO:0001675)10.7482154
176epithelial cilium movement (GO:0003351)10.2876365
177axonemal dynein complex assembly (GO:0070286)10.1983087

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.04861201
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.04739634
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.91359310
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.52189478
5EZH2_22144423_ChIP-Seq_EOC_Human3.01548933
6GBX2_23144817_ChIP-Seq_PC3_Human2.72663102
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.48304481
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.38345878
9STAT6_21828071_ChIP-Seq_BEAS2B_Human2.32870701
10PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.27886384
11PCGF2_27294783_Chip-Seq_ESCs_Mouse2.16173108
12MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.12168170
13IGF1R_20145208_ChIP-Seq_DFB_Human2.10895629
14CTBP1_25329375_ChIP-Seq_LNCAP_Human2.01867323
15ER_23166858_ChIP-Seq_MCF-7_Human1.96627929
16POU3F2_20337985_ChIP-ChIP_501MEL_Human1.91901324
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.86891933
18KAP1_22055183_ChIP-Seq_ESCs_Mouse1.84799287
19EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.83422852
20TAL1_26923725_Chip-Seq_HPCs_Mouse1.81144114
21CBX2_27304074_Chip-Seq_ESCs_Mouse1.79675354
22EWS_26573619_Chip-Seq_HEK293_Human1.78134914
23P300_19829295_ChIP-Seq_ESCs_Human1.77737539
24SALL1_21062744_ChIP-ChIP_HESCs_Human1.76392920
25STAT1_17558387_ChIP-Seq_HELA_Human1.76075036
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.75097585
27KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.71133006
28VDR_22108803_ChIP-Seq_LS180_Human1.67187166
29HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.65270351
30NFE2_27457419_Chip-Seq_LIVER_Mouse1.62181328
31SOX2_22085726_ChIP-Seq_NPCs_Mouse1.61117966
32GATA1_26923725_Chip-Seq_HPCs_Mouse1.60972705
33BCAT_22108803_ChIP-Seq_LS180_Human1.60322935
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.60085840
35KDM2B_26808549_Chip-Seq_REH_Human1.59558157
36GATA3_21867929_ChIP-Seq_TH1_Mouse1.58810370
37RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.58133221
38GATA3_21867929_ChIP-Seq_CD8_Mouse1.57628562
39* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.55663179
40SUZ12_27294783_Chip-Seq_NPCs_Mouse1.54383773
41PCGF2_27294783_Chip-Seq_NPCs_Mouse1.53800179
42TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.53010492
43TP53_22573176_ChIP-Seq_HFKS_Human1.52903170
44MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.51224351
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.50451868
46CBP_20019798_ChIP-Seq_JUKART_Human1.50451868
47IRF1_19129219_ChIP-ChIP_H3396_Human1.48468686
48REST_21632747_ChIP-Seq_MESCs_Mouse1.48175428
49PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.47861508
50TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.47811146
51NOTCH1_21737748_ChIP-Seq_TLL_Human1.47545404
52STAT3_23295773_ChIP-Seq_U87_Human1.47000643
53BMI1_23680149_ChIP-Seq_NPCS_Mouse1.45479615
54AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.44821334
55FOXA1_25329375_ChIP-Seq_VCAP_Human1.43811483
56FOXA1_27270436_Chip-Seq_PROSTATE_Human1.43811483
57UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.42980526
58ZNF274_21170338_ChIP-Seq_K562_Hela1.42237716
59FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41125173
60SMAD4_21799915_ChIP-Seq_A2780_Human1.37987927
61GATA3_21878914_ChIP-Seq_MCF-7_Human1.36866303
62* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.36729773
63SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36533756
64PIAS1_25552417_ChIP-Seq_VCAP_Human1.36074894
65NR3C1_21868756_ChIP-Seq_MCF10A_Human1.35954095
66TCF4_23295773_ChIP-Seq_U87_Human1.35847338
67PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.35048398
68SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.35043264
69* AR_25329375_ChIP-Seq_VCAP_Human1.34054981
70NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.33171853
71ETV2_25802403_ChIP-Seq_MESCs_Mouse1.32099105
72OCT4_18555785_Chip-Seq_ESCs_Mouse1.32030860
73PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.31848678
74DROSHA_22980978_ChIP-Seq_HELA_Human1.31067223
75NANOG_19829295_ChIP-Seq_ESCs_Human1.30827178
76SOX2_19829295_ChIP-Seq_ESCs_Human1.30827178
77EZH2_27294783_Chip-Seq_NPCs_Mouse1.30753683
78P53_22387025_ChIP-Seq_ESCs_Mouse1.30455190
79ELK4_26923725_Chip-Seq_MESODERM_Mouse1.30451572
80ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.30366576
81CRX_20693478_ChIP-Seq_RETINA_Mouse1.30077350
82NANOG_18555785_Chip-Seq_ESCs_Mouse1.29855520
83GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.29117747
84GF1_26923725_Chip-Seq_HPCs_Mouse1.28528707
85TAF15_26573619_Chip-Seq_HEK293_Human1.28199440
86EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.27786855
87CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.27470770
88CMYC_18555785_Chip-Seq_ESCs_Mouse1.26168374
89TCF4_22108803_ChIP-Seq_LS180_Human1.24760070
90MYC_18940864_ChIP-ChIP_HL60_Human1.24405265
91CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.23561280
92SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.23453464
93PRDM14_20953172_ChIP-Seq_ESCs_Human1.23098193
94P300_18555785_Chip-Seq_ESCs_Mouse1.22927770
95SMAD3_21741376_ChIP-Seq_EPCs_Human1.22685044
96CTBP2_25329375_ChIP-Seq_LNCAP_Human1.22595925
97NCOR_22424771_ChIP-Seq_293T_Human1.22305364
98* SMAD4_21741376_ChIP-Seq_EPCs_Human1.22166991
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.21401577
100IRF8_27001747_Chip-Seq_BMDM_Mouse1.21268079
101FUS_26573619_Chip-Seq_HEK293_Human1.21196866
102CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.20957457
103EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.20876147
104WDR5_24793694_ChIP-Seq_LNCAP_Human1.20522298
105P53_21459846_ChIP-Seq_SAOS-2_Human1.20493944
106GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.20134819
107MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19598198
108RUNX2_22187159_ChIP-Seq_PCA_Human1.19179176
109FOXA1_21572438_ChIP-Seq_LNCaP_Human1.18335111
110HOXB7_26014856_ChIP-Seq_BT474_Human1.18244100
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18107497
112AR_20517297_ChIP-Seq_VCAP_Human1.17618733
113STAT3_18555785_Chip-Seq_ESCs_Mouse1.17522987
114EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.17315622
115* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.16995189
116SUZ12_18555785_Chip-Seq_ESCs_Mouse1.15467129
117SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.13895311
118ESRRB_18555785_Chip-Seq_ESCs_Mouse1.13866084
119AR_21572438_ChIP-Seq_LNCaP_Human1.13236619
120KLF4_18555785_Chip-Seq_ESCs_Mouse1.13115605
121MYC_19829295_ChIP-Seq_ESCs_Human1.12918842
122NFIB_24661679_ChIP-Seq_LUNG_Mouse1.12184398
123RNF2_27304074_Chip-Seq_NSC_Mouse1.11978281
124OCT4_21477851_ChIP-Seq_ESCs_Mouse1.11615315
125LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.11232486
126FLI1_21867929_ChIP-Seq_TH2_Mouse1.11039278
127Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.08781418
128ESET_19884257_ChIP-Seq_ESCs_Mouse1.08751964
129POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08580201
130TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08580201
131SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.08308769
132E2F1_18555785_Chip-Seq_ESCs_Mouse1.07920388
133LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.07677795
134ERA_21632823_ChIP-Seq_H3396_Human1.07118945
135RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06912759
136PU1_27457419_Chip-Seq_LIVER_Mouse1.06245480
137IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.05776239
138RUNX1_27457419_Chip-Seq_LIVER_Mouse1.05761140
139SOX2_18555785_Chip-Seq_ESCs_Mouse1.05455711
140KLF5_20875108_ChIP-Seq_MESCs_Mouse1.05055025
141NMYC_18555785_Chip-Seq_ESCs_Mouse1.04971416
142RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.04960225
143* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.04749620
144SCL_19346495_ChIP-Seq_HPC-7_Human1.03962159
145* FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03924055
146RAD21_21589869_ChIP-Seq_MESCs_Mouse1.03894620
147RUNX1_26923725_Chip-Seq_HPCs_Mouse1.03015573
148NANOG_20526341_ChIP-Seq_ESCs_Human1.02918630
149LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse1.02798309
150PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02120549
151CTCF_18555785_Chip-Seq_ESCs_Mouse1.02093988
152AUTS2_25519132_ChIP-Seq_293T-REX_Human1.00711198
153KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.00634149
154SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00621289
155* TAF2_19829295_ChIP-Seq_ESCs_Human1.00271241
156GABP_17652178_ChIP-ChIP_JURKAT_Human1.00235176
157GF1B_26923725_Chip-Seq_HPCs_Mouse1.00139093
158OCT4_20526341_ChIP-Seq_ESCs_Human0.99832568
159CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99690868
160* TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.99643394
161PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.98547297
162ETV1_20927104_ChIP-Seq_GIST48_Human0.97839541
163SPI1_26923725_Chip-Seq_HPCs_Mouse0.97497379
164CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.96502106
165TDRD3_21172665_ChIP-Seq_MCF-7_Human0.96204319
166FOXH1_21741376_ChIP-Seq_EPCs_Human0.95721575
167CDX2_22108803_ChIP-Seq_LS180_Human0.94761050

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.49390985
2MP0001929_abnormal_gametogenesis5.08453562
3MP0008877_abnormal_DNA_methylation4.17895762
4MP0002210_abnormal_sex_determination3.17950203
5MP0002161_abnormal_fertility/fecundity2.87082951
6MP0003195_calcinosis2.68820599
7MP0001145_abnormal_male_reproductive2.64484199
8MP0008875_abnormal_xenobiotic_pharmacok2.51519117
9MP0005551_abnormal_eye_electrophysiolog2.44689638
10MP0000569_abnormal_digit_pigmentation2.38047504
11MP0005670_abnormal_white_adipose2.31945334
12MP0002876_abnormal_thyroid_physiology2.29672949
13MP0000653_abnormal_sex_gland2.26700257
14MP0002102_abnormal_ear_morphology2.23487069
15MP0001485_abnormal_pinna_reflex2.02023418
16MP0002837_dystrophic_cardiac_calcinosis2.01810098
17MP0004043_abnormal_pH_regulation2.00399852
18MP0005410_abnormal_fertilization14.8891507
19MP0004133_heterotaxia1.98788895
20MP0009745_abnormal_behavioral_response1.93080587
21MP0004885_abnormal_endolymph1.92392536
22MP0008872_abnormal_physiological_respon1.78721012
23MP0004142_abnormal_muscle_tone1.76714297
24MP0005623_abnormal_meninges_morphology1.73460070
25MP0002234_abnormal_pharynx_morphology1.72101054
26MP0002638_abnormal_pupillary_reflex1.71927389
27MP0001986_abnormal_taste_sensitivity1.69686232
28MP0006072_abnormal_retinal_apoptosis1.69441669
29MP0001501_abnormal_sleep_pattern1.69032564
30MP0000427_abnormal_hair_cycle1.67949348
31MP0002272_abnormal_nervous_system1.66713341
32MP0005377_hearing/vestibular/ear_phenot1.64134568
33MP0003878_abnormal_ear_physiology1.64134568
34MP0005253_abnormal_eye_physiology1.59388529
35MP0005645_abnormal_hypothalamus_physiol1.57161577
36MP0002653_abnormal_ependyma_morphology1.54289901
37MP0002160_abnormal_reproductive_system1.48784556
38MP0000631_abnormal_neuroendocrine_gland1.48700992
39MP0006276_abnormal_autonomic_nervous1.48491673
40MP0001835_abnormal_antigen_presentation1.46534361
41MP0002735_abnormal_chemical_nociception1.43398229
42MP0001486_abnormal_startle_reflex1.41917620
43MP0008057_abnormal_DNA_replication1.40689649
44MP0006292_abnormal_olfactory_placode1.37009330
45MP0002572_abnormal_emotion/affect_behav1.35858731
46MP0000372_irregular_coat_pigmentation1.35305185
47MP0005397_hematopoietic_system_phenotyp1.31209954
48MP0001545_abnormal_hematopoietic_system1.31209954
49MP0009785_altered_susceptibility_to1.30529730
50MP0002064_seizures1.29443863
51MP0001970_abnormal_pain_threshold1.29352506
52MP0002132_abnormal_respiratory_system1.27863529
53MP0003283_abnormal_digestive_organ1.25635408
54MP0002557_abnormal_social/conspecific_i1.24781209
55MP0003787_abnormal_imprinting1.24460199
56MP0002736_abnormal_nociception_after1.23658752
57MP0002282_abnormal_trachea_morphology1.22447569
58MP0003880_abnormal_central_pattern1.16496568
59MP0005084_abnormal_gallbladder_morpholo1.16350612
60MP0010386_abnormal_urinary_bladder1.16345772
61MP0009278_abnormal_bone_marrow1.16086319
62MP0002733_abnormal_thermal_nociception1.15662840
63MP0002909_abnormal_adrenal_gland1.13904692
64MP0005423_abnormal_somatic_nervous1.12795968
65MP0002928_abnormal_bile_duct1.12168891
66MP0000383_abnormal_hair_follicle1.11012556
67MP0002067_abnormal_sensory_capabilities1.08876530
68MP0005025_abnormal_response_to1.08300294
69MP0002148_abnormal_hypersensitivity_rea1.06694008
70MP0004233_abnormal_muscle_weight1.06267405
71MP0005174_abnormal_tail_pigmentation1.05920208
72MP0005379_endocrine/exocrine_gland_phen1.05040257
73MP0005386_behavior/neurological_phenoty1.03950959
74MP0004924_abnormal_behavior1.03950959
75MP0002938_white_spotting1.03679168
76MP0003635_abnormal_synaptic_transmissio1.01300488
77MP0003436_decreased_susceptibility_to1.01284276
78MP0004808_abnormal_hematopoietic_stem1.01199092
79MP0002163_abnormal_gland_morphology1.00663485
80MP0002063_abnormal_learning/memory/cond0.99659596
81MP0002734_abnormal_mechanical_nocicepti0.99650424
82MP0001919_abnormal_reproductive_system0.97826181
83MP0004145_abnormal_muscle_electrophysio0.96798436
84MP0001765_abnormal_ion_homeostasis0.96236990
85MP0001905_abnormal_dopamine_level0.95564436
86MP0001529_abnormal_vocalization0.95533399
87MP0005195_abnormal_posterior_eye0.95102923
88MP0008058_abnormal_DNA_repair0.94151834
89MP0006054_spinal_hemorrhage0.92960895
90MP0003183_abnormal_peptide_metabolism0.92468774
91MP0002229_neurodegeneration0.91078219
92MP0002138_abnormal_hepatobiliary_system0.89751314
93MP0001963_abnormal_hearing_physiology0.88384234
94MP0000685_abnormal_immune_system0.87871825
95MP0008995_early_reproductive_senescence0.86830132
96MP0002095_abnormal_skin_pigmentation0.85832446
97MP0003252_abnormal_bile_duct0.82455911
98MP0002405_respiratory_system_inflammati0.80853795
99MP0002752_abnormal_somatic_nervous0.79907480
100MP0001873_stomach_inflammation0.79353257
101MP0004147_increased_porphyrin_level0.78785963
102MP0003045_fibrosis0.78127527
103MP0002419_abnormal_innate_immunity0.77898229
104MP0000230_abnormal_systemic_arterial0.76958520
105MP0001984_abnormal_olfaction0.76653594
106MP0005389_reproductive_system_phenotype0.76564725
107MP0004130_abnormal_muscle_cell0.75759982
108MP0005000_abnormal_immune_tolerance0.75495616
109MP0005646_abnormal_pituitary_gland0.74238177
110MP0003137_abnormal_impulse_conducting0.73220859
111MP0003718_maternal_effect0.73115988
112MP0002723_abnormal_immune_serum0.72088940
113MP0001324_abnormal_eye_pigmentation0.72024839
114MP0005310_abnormal_salivary_gland0.70913606
115MP0001944_abnormal_pancreas_morphology0.70398051
116MP0005464_abnormal_platelet_physiology0.67037341
117MP0005387_immune_system_phenotype0.66936225
118MP0001790_abnormal_immune_system0.66936225
119MP0005167_abnormal_blood-brain_barrier0.66080445
120MP0002452_abnormal_antigen_presenting0.65403926
121MP0005671_abnormal_response_to0.63740240
122MP0003136_yellow_coat_color0.61643414
123MP0005409_darkened_coat_color0.61539521
124MP0001968_abnormal_touch/_nociception0.61214459
125MP0001119_abnormal_female_reproductive0.61117812
126MP0000490_abnormal_crypts_of0.60079375
127MP0002420_abnormal_adaptive_immunity0.59269195
128MP0002139_abnormal_hepatobiliary_system0.59192892
129MP0001819_abnormal_immune_cell0.59112313
130MP0003646_muscle_fatigue0.55492377
131MP0001800_abnormal_humoral_immune0.55250090
132MP0001851_eye_inflammation0.54212745
133MP0010094_abnormal_chromosome_stability0.53188980
134MP0000343_altered_response_to0.50595943
135MP0003724_increased_susceptibility_to0.47545370
136MP0005075_abnormal_melanosome_morpholog0.47309171
137MP0000716_abnormal_immune_system0.46528597
138MP0002398_abnormal_bone_marrow0.45370780
139MP0005647_abnormal_sex_gland0.44523675
140MP0005636_abnormal_mineral_homeostasis0.44076665
141MP0003868_abnormal_feces_composition0.43349497
142MP0001293_anophthalmia0.42666665
143MP0009046_muscle_twitch0.40987365
144MP0003011_delayed_dark_adaptation0.40936756
145MP0008004_abnormal_stomach_pH0.40778560
146MP0003115_abnormal_respiratory_system0.40169233
147MP0004742_abnormal_vestibular_system0.40008306
148MP0000015_abnormal_ear_pigmentation0.38940000
149MP0003786_premature_aging0.36566421
150MP0008789_abnormal_olfactory_epithelium0.36564212
151MP0002277_abnormal_respiratory_mucosa0.35734615
152MP0003699_abnormal_female_reproductive0.35543782
153MP0008469_abnormal_protein_level0.35424879
154MP0001502_abnormal_circadian_rhythm0.35407760
155MP0001845_abnormal_inflammatory_respons0.34906845
156MP0003121_genomic_imprinting0.32970276
157MP0003866_abnormal_defecation0.32631373
158MP0002429_abnormal_blood_cell0.32500593
159MP0000858_altered_metastatic_potential0.32343809
160MP0003763_abnormal_thymus_physiology0.32073002
161MP0000689_abnormal_spleen_morphology0.31526553
162MP0008007_abnormal_cellular_replicative0.31444134
163MP0002693_abnormal_pancreas_physiology0.30985068
164MP0003111_abnormal_nucleus_morphology0.30713097
165MP0004782_abnormal_surfactant_physiolog0.30677584
166MP0006036_abnormal_mitochondrial_physio0.28693636
167MP0009250_abnormal_appendicular_skeleto0.26512381
168MP0000026_abnormal_inner_ear0.26196388

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.15733340
2Abnormal respiratory motile cilium morphology (HP:0005938)9.15733340
3Abnormal respiratory motile cilium physiology (HP:0012261)8.85219242
4Abnormal ciliary motility (HP:0012262)7.41500897
5Rhinitis (HP:0012384)7.12606015
6Chronic bronchitis (HP:0004469)6.60950419
7Nasal polyposis (HP:0100582)6.52063297
8Infertility (HP:0000789)5.77054045
9Abnormality of the nasal mucosa (HP:0000433)5.47268906
10Bronchitis (HP:0012387)4.61983825
11Bronchiectasis (HP:0002110)4.53821234
12Congenital stationary night blindness (HP:0007642)3.79850701
13Recurrent sinusitis (HP:0011108)3.69751134
14Male infertility (HP:0003251)3.67502437
15Nephronophthisis (HP:0000090)3.60679340
16Abnormal spermatogenesis (HP:0008669)3.44997180
17Recurrent bronchitis (HP:0002837)3.29339429
18Recurrent otitis media (HP:0000403)3.14166829
19Attenuation of retinal blood vessels (HP:0007843)3.07296010
20Type II lissencephaly (HP:0007260)3.06890047
21Pendular nystagmus (HP:0012043)2.88941877
22Abnormality of the renal medulla (HP:0100957)2.81636618
23Tubulointerstitial nephritis (HP:0001970)2.79032225
24Abnormal rod and cone electroretinograms (HP:0008323)2.74373510
25Abolished electroretinogram (ERG) (HP:0000550)2.67779004
26Abnormal biliary tract physiology (HP:0012439)2.67196360
27Bile duct proliferation (HP:0001408)2.67196360
28Sclerocornea (HP:0000647)2.65957905
29Azoospermia (HP:0000027)2.59872369
30Chronic sinusitis (HP:0011109)2.55743158
31Medial flaring of the eyebrow (HP:0010747)2.49568149
32Molar tooth sign on MRI (HP:0002419)2.49093098
33Abnormality of midbrain morphology (HP:0002418)2.49093098
34Anencephaly (HP:0002323)2.47577350
35Furrowed tongue (HP:0000221)2.45512809
36Gaze-evoked nystagmus (HP:0000640)2.43344090
37Keratoconus (HP:0000563)2.42445590
38Increased corneal curvature (HP:0100692)2.42445590
39Absent rod-and cone-mediated responses on ERG (HP:0007688)2.41058273
40Hyperventilation (HP:0002883)2.40751103
41Large for gestational age (HP:0001520)2.38873432
42Decreased circulating renin level (HP:0003351)2.35891136
43Abnormality of alanine metabolism (HP:0010916)2.35490203
44Hyperalaninemia (HP:0003348)2.35490203
45Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.35490203
46Progressive inability to walk (HP:0002505)2.33937863
47Male pseudohermaphroditism (HP:0000037)2.33318011
48Impulsivity (HP:0100710)2.32786894
49Asymmetric septal hypertrophy (HP:0001670)2.32471282
50Occipital encephalocele (HP:0002085)2.31949019
51Genetic anticipation (HP:0003743)2.27343684
52Aplasia/Hypoplasia of the tongue (HP:0010295)2.26469333
53Tubular atrophy (HP:0000092)2.25735008
54Progressive cerebellar ataxia (HP:0002073)2.24856652
55Gonadotropin excess (HP:0000837)2.23415191
56Inability to walk (HP:0002540)2.20614172
57Decreased central vision (HP:0007663)2.15468769
58Bony spicule pigmentary retinopathy (HP:0007737)2.13420358
59Neonatal hypoglycemia (HP:0001998)2.08949624
60Concave nail (HP:0001598)2.07379493
61Bundle branch block (HP:0011710)2.05732407
62Cerebellar dysplasia (HP:0007033)2.04467217
63Dyschromatopsia (HP:0007641)2.04214747
64Lissencephaly (HP:0001339)2.02412626
65Renal cortical cysts (HP:0000803)2.00785753
66Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.2785268
67Absent/shortened dynein arms (HP:0200106)12.1033207
68Dynein arm defect of respiratory motile cilia (HP:0012255)12.1033207
69Stomach cancer (HP:0012126)1.99128369
70Genital tract atresia (HP:0001827)1.98183291
71Tubulointerstitial abnormality (HP:0001969)1.97509420
72Abnormality of the pons (HP:0007361)1.95443778
73Vaginal atresia (HP:0000148)1.92731653
74Congenital hepatic fibrosis (HP:0002612)1.91234526
753-Methylglutaconic aciduria (HP:0003535)1.91073351
76Decreased electroretinogram (ERG) amplitude (HP:0000654)1.89759178
77Broad-based gait (HP:0002136)1.89259507
78Chorioretinal atrophy (HP:0000533)1.89213765
79Supernumerary spleens (HP:0009799)1.88800711
80Hypoplasia of the pons (HP:0012110)1.85162985
81Congenital, generalized hypertrichosis (HP:0004540)1.84363619
82Cholecystitis (HP:0001082)1.84053011
83Abnormal gallbladder physiology (HP:0012438)1.84053011
84Abnormality of macular pigmentation (HP:0008002)1.78584246
85Abnormality of permanent molar morphology (HP:0011071)1.78567728
86Abnormality of the dental root (HP:0006486)1.78567728
87Taurodontia (HP:0000679)1.78567728
88Easy fatigability (HP:0003388)1.77926082
89Polydipsia (HP:0001959)1.77390595
90Abnormal drinking behavior (HP:0030082)1.77390595
91Abnormality of molar morphology (HP:0011070)1.74552394
92Abnormality of molar (HP:0011077)1.74552394
93Optic disc pallor (HP:0000543)1.73745583
94True hermaphroditism (HP:0010459)1.72954270
95Hemiparesis (HP:0001269)1.72419529
96Tachypnea (HP:0002789)1.70963083
97Congenital sensorineural hearing impairment (HP:0008527)1.70849507
98Methylmalonic acidemia (HP:0002912)1.70385649
99Retrobulbar optic neuritis (HP:0100654)1.70278394
100Optic neuritis (HP:0100653)1.70278394
101Retinal dysplasia (HP:0007973)1.70094062
102Aplasia/Hypoplasia of the tibia (HP:0005772)1.70031638
103Ketoacidosis (HP:0001993)1.69866380
104Retinitis pigmentosa (HP:0000510)1.69707697
105Preaxial hand polydactyly (HP:0001177)1.69531168
106Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.69344476
107Patellar aplasia (HP:0006443)1.69254128
108Aplasia/Hypoplasia of the patella (HP:0006498)1.67932449
109Stage 5 chronic kidney disease (HP:0003774)1.67846513
110Type 2 muscle fiber atrophy (HP:0003554)1.67561855
111Severe muscular hypotonia (HP:0006829)1.67389512
112Hypothermia (HP:0002045)1.67026444
113Mitochondrial inheritance (HP:0001427)1.66362422
114Acute necrotizing encephalopathy (HP:0006965)1.63243375
115Agitation (HP:0000713)1.63207575
116Aplasia/hypoplasia of the uterus (HP:0008684)1.62843331
117Cystic liver disease (HP:0006706)1.62017915
118Heterotopia (HP:0002282)1.60726095
119Postaxial foot polydactyly (HP:0001830)1.59497358
120Muscle fiber atrophy (HP:0100295)1.57855533
121Abnormality of the dental pulp (HP:0006479)1.56658036
122Abnormality of the renal cortex (HP:0011035)1.55476799
123Congenital primary aphakia (HP:0007707)1.54231274
124Pancreatic fibrosis (HP:0100732)1.53045628
125Abnormality of renal excretion (HP:0011036)1.52663090
126Recurrent gram-negative bacterial infections (HP:0005420)1.52581157
127Abdominal situs inversus (HP:0003363)1.52393413
128Abnormality of abdominal situs (HP:0011620)1.52393413
129Pancreatic cysts (HP:0001737)1.52156665
130Orchitis (HP:0100796)1.50274708
131Chronic hepatic failure (HP:0100626)1.49742454
132Gait imbalance (HP:0002141)1.49548450
133Choroideremia (HP:0001139)1.49386215
134Myositis (HP:0100614)1.48274318
135Chronic otitis media (HP:0000389)1.48124830
136Asplenia (HP:0001746)1.48075149
137Aplasia/Hypoplasia of the lens (HP:0008063)1.44261624
138Abnormality of the neuromuscular junction (HP:0003398)1.37735956
139Fatigable weakness (HP:0003473)1.37735956
140Renal dysplasia (HP:0000110)1.36472214
141Papilledema (HP:0001085)1.35796832
142Postaxial hand polydactyly (HP:0001162)1.33191702
143Poor coordination (HP:0002370)1.32174687
144Abnormal urine output (HP:0012590)1.30084563
145Nephrogenic diabetes insipidus (HP:0009806)1.29374599
146Aplasia/Hypoplasia of the spleen (HP:0010451)1.28928601
147Tubulointerstitial fibrosis (HP:0005576)1.27944633
148Loss of speech (HP:0002371)1.27124014
149Hypoplasia of the capital femoral epiphysis (HP:0003090)1.26724953
150Nephropathy (HP:0000112)1.25591323
151Weak cry (HP:0001612)1.20660265
152Renovascular hypertension (HP:0100817)1.20444475
153Polyuria (HP:0000103)1.20358611
154Optic nerve hypoplasia (HP:0000609)1.20248671
155Abnormality of dentin (HP:0010299)1.19672555
156Absent frontal sinuses (HP:0002688)1.19644743
157Recurrent bacterial skin infections (HP:0005406)1.17285249
158Impaired proprioception (HP:0010831)1.17202865
159Constricted visual fields (HP:0001133)1.17162873
160Recurrent abscess formation (HP:0002722)1.15515740
161Chromosomal breakage induced by crosslinking agents (HP:0003221)1.14187784

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK47.53772669
2PDK37.53772669
3FRK5.93791776
4TESK15.33726690
5PDK25.02299553
6PRKD33.61442907
7ICK3.28182311
8NME22.76264319
9MAP4K22.71566110
10BMPR1B2.64490119
11TLK12.55845776
12WNK32.44861528
13ZAK2.41840860
14STK162.16083264
15ACVR1B2.15636611
16INSRR2.07743221
17STK382.00776539
18NUAK11.88474194
19PTK2B1.82951759
20RIPK41.74502780
21OXSR11.71639331
22STK391.61301298
23NEK21.39785031
24WNK41.39766997
25CASK1.38317457
26SIK21.34991058
27DAPK21.33681194
28PDK11.32541207
29MAP3K41.30071106
30DYRK1B1.28947753
31MAPK151.26359049
32ADRBK11.24470194
33MAP2K61.21566069
34NTRK21.21424595
35IRAK11.20611239
36IRAK41.16533895
37CAMKK21.12952368
38PNCK1.12354927
39PAK31.10626559
40PASK1.08580101
41MAPKAPK31.02915052
42PRKCG0.99529283
43NTRK30.98171912
44MUSK0.98167730
45VRK10.97979088
46MST40.97705637
47CLK10.97221747
48DYRK20.97116522
49TRIM280.96387112
50MAP3K140.94720046
51PHKG20.91741341
52PHKG10.91741341
53LMTK20.90839953
54PLK20.89996321
55TXK0.89578046
56NEK60.89273076
57MARK10.87324540
58TGFBR10.85878045
59PAK40.84749509
60PRKCE0.83303882
61DYRK30.83085475
62TAOK30.80956720
63MAP2K30.80771128
64STK38L0.79930661
65FGFR20.79929875
66MKNK20.75520964
67PDPK10.74909652
68MAPKAPK50.74499316
69MAP4K10.73699045
70STK110.72433372
71IRAK20.72357931
72TNK20.70059192
73CSNK1G20.67389278
74BTK0.66183039
75PRKCI0.64995179
76KIT0.63855308
77NLK0.63340326
78BCR0.63200734
79TTK0.63076055
80PLK40.61025145
81ITK0.60549984
82MAP2K70.57706373
83CCNB10.56023929
84PINK10.55857209
85PKN10.55157931
86CSNK1G10.55031761
87WEE10.54947197
88NME10.54261168
89PIK3CG0.54116735
90RPS6KB10.52491764
91YES10.49478344
92CAMK2A0.49143786
93WNK10.47613347
94EEF2K0.47295754
95CAMK10.47076103
96PRKACA0.46493841
97BCKDK0.46367747
98TBK10.45831222
99RPS6KA50.45722501
100ZAP700.44711668
101TEC0.44535881
102CSNK1G30.44411081
103CDK60.44128364
104MAP2K20.41601241
105CSNK1A10.40956070
106ATR0.40861091
107PRKCZ0.39411438
108PRKCA0.39190814
109GRK10.38859814
110PRKAA10.37258841
111ERBB30.37202190
112CSNK1D0.37040461
113GRK60.37034169
114SYK0.36216762
115ATM0.35716736
116EIF2AK20.35434433
117STK30.34979448
118PIM10.34706707
119PRKCH0.34655782
120PRKAA20.33716079
121IKBKE0.33446518
122CSNK1A1L0.33031886
123TNIK0.32654145
124GRK50.31886400
125PRKG20.31388773
126NEK90.31091566
127MAP3K120.30477725
128CHEK20.30166067
129MAP2K10.29499751
130ADRBK20.29014063
131IKBKB0.28887245
132RPS6KA40.26730613
133CHUK0.25874648
134PIK3CA0.25419112
135EIF2AK30.24476799
136PRKCD0.23040203
137RIPK10.22755839
138TIE10.21152386
139STK40.19973317
140CSNK2A10.19313774
141HCK0.19304795
142BMPR20.19033345
143MAPK130.18969255
144MATK0.17979775
145CHEK10.17308844
146PRKG10.17307873
147EIF2AK10.17066313
148LCK0.16193137
149EPHA20.14557711
150MAP3K110.14411198
151MAP3K30.13969392
152PIM20.13896618
153PTK60.13133830
154PRKCQ0.12684337
155FGFR30.12073872
156BRSK20.11845051
157CAMKK10.11413660
158LYN0.11097064
159CAMK1G0.10615100
160RPS6KA10.09605379
161PLK10.09339103
162TRPM70.09218040

Predicted pathways (KEGG)

RankGene SetZ-score
1alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.18323488
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.08631889
3Linoleic acid metabolism_Homo sapiens_hsa005913.05122832
4Fatty acid biosynthesis_Homo sapiens_hsa000613.02021653
5Basal transcription factors_Homo sapiens_hsa030222.84011708
6Phototransduction_Homo sapiens_hsa047442.74092972
7Glycosaminoglycan degradation_Homo sapiens_hsa005312.70104203
8Fanconi anemia pathway_Homo sapiens_hsa034602.66307878
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.54790649
10Nitrogen metabolism_Homo sapiens_hsa009102.48420496
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.38414651
12Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.35854095
13Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.31301506
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.30523267
15Vitamin B6 metabolism_Homo sapiens_hsa007502.29620934
16Maturity onset diabetes of the young_Homo sapiens_hsa049502.26079910
17Nicotine addiction_Homo sapiens_hsa050332.21593224
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.19583475
19Butanoate metabolism_Homo sapiens_hsa006502.19283700
20Glucagon signaling pathway_Homo sapiens_hsa049222.17060977
21Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.10353168
22Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.08194026
23Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.06021152
24Pyruvate metabolism_Homo sapiens_hsa006202.05885962
25Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.96395362
26Carbohydrate digestion and absorption_Homo sapiens_hsa049731.92315199
27Oxidative phosphorylation_Homo sapiens_hsa001901.86995354
28Selenocompound metabolism_Homo sapiens_hsa004501.74924750
29Propanoate metabolism_Homo sapiens_hsa006401.73973054
30Caffeine metabolism_Homo sapiens_hsa002321.72998518
31Antigen processing and presentation_Homo sapiens_hsa046121.71393660
32Arachidonic acid metabolism_Homo sapiens_hsa005901.66637433
33Ether lipid metabolism_Homo sapiens_hsa005651.63821213
34Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.62905153
35Tryptophan metabolism_Homo sapiens_hsa003801.61673748
36Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.59324645
37Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.58203425
38Legionellosis_Homo sapiens_hsa051341.49271706
39Glycerophospholipid metabolism_Homo sapiens_hsa005641.42973118
40Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.42137434
41Dorso-ventral axis formation_Homo sapiens_hsa043201.40690968
42Olfactory transduction_Homo sapiens_hsa047401.38361570
43Mineral absorption_Homo sapiens_hsa049781.36870241
44Protein export_Homo sapiens_hsa030601.33700699
45Morphine addiction_Homo sapiens_hsa050321.33615036
46RNA polymerase_Homo sapiens_hsa030201.32058526
47Glycerolipid metabolism_Homo sapiens_hsa005611.28316168
48PPAR signaling pathway_Homo sapiens_hsa033201.27859801
49Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.27331620
50Purine metabolism_Homo sapiens_hsa002301.25498028
51Steroid hormone biosynthesis_Homo sapiens_hsa001401.24747999
52Parkinsons disease_Homo sapiens_hsa050121.24136655
53Oocyte meiosis_Homo sapiens_hsa041141.23895598
54Measles_Homo sapiens_hsa051621.23883844
55Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.21110856
56Peroxisome_Homo sapiens_hsa041461.20380282
57Renin secretion_Homo sapiens_hsa049241.20017167
58Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.19143305
59Allograft rejection_Homo sapiens_hsa053301.17519478
60Histidine metabolism_Homo sapiens_hsa003401.17135866
61Pentose phosphate pathway_Homo sapiens_hsa000301.16692199
62Retinol metabolism_Homo sapiens_hsa008301.16372480
63Fructose and mannose metabolism_Homo sapiens_hsa000511.14280208
64Regulation of autophagy_Homo sapiens_hsa041401.12093323
65Primary bile acid biosynthesis_Homo sapiens_hsa001201.02868417
66Other glycan degradation_Homo sapiens_hsa005111.01100455
67Influenza A_Homo sapiens_hsa051641.00861055
68B cell receptor signaling pathway_Homo sapiens_hsa046620.98434364
69beta-Alanine metabolism_Homo sapiens_hsa004100.94442750
70Huntingtons disease_Homo sapiens_hsa050160.94399441
71Serotonergic synapse_Homo sapiens_hsa047260.93166965
72mRNA surveillance pathway_Homo sapiens_hsa030150.91259294
73Pyrimidine metabolism_Homo sapiens_hsa002400.91023312
74Circadian entrainment_Homo sapiens_hsa047130.90282436
75Herpes simplex infection_Homo sapiens_hsa051680.87373745
76Alzheimers disease_Homo sapiens_hsa050100.87252646
77Glutamatergic synapse_Homo sapiens_hsa047240.86934059
78GABAergic synapse_Homo sapiens_hsa047270.83729853
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.83308836
80Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.81608774
81Type I diabetes mellitus_Homo sapiens_hsa049400.81114423
82Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.80859381
83RNA degradation_Homo sapiens_hsa030180.80532951
84Leishmaniasis_Homo sapiens_hsa051400.79919415
85Ovarian steroidogenesis_Homo sapiens_hsa049130.79535318
86Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.78805146
87Graft-versus-host disease_Homo sapiens_hsa053320.77963905
88NF-kappa B signaling pathway_Homo sapiens_hsa040640.77441195
89RNA transport_Homo sapiens_hsa030130.76934357
90Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.76624214
91Sulfur metabolism_Homo sapiens_hsa009200.75541705
92Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.74949313
93DNA replication_Homo sapiens_hsa030300.74817673
94Protein digestion and absorption_Homo sapiens_hsa049740.74753080
95Salmonella infection_Homo sapiens_hsa051320.73586255
96Glutathione metabolism_Homo sapiens_hsa004800.71502458
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.70956104
98Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.70560403
99Taste transduction_Homo sapiens_hsa047420.69511520
100Intestinal immune network for IgA production_Homo sapiens_hsa046720.68100285
101ABC transporters_Homo sapiens_hsa020100.67699191
102Amphetamine addiction_Homo sapiens_hsa050310.67056589
103NOD-like receptor signaling pathway_Homo sapiens_hsa046210.65500909
104Asthma_Homo sapiens_hsa053100.64036737
105Calcium signaling pathway_Homo sapiens_hsa040200.64027570
106Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.63983714
107Osteoclast differentiation_Homo sapiens_hsa043800.63408887
108Circadian rhythm_Homo sapiens_hsa047100.62532149
109Pancreatic secretion_Homo sapiens_hsa049720.62526512
110One carbon pool by folate_Homo sapiens_hsa006700.61551398
111Insulin secretion_Homo sapiens_hsa049110.60570283
112Fat digestion and absorption_Homo sapiens_hsa049750.59485691
113Autoimmune thyroid disease_Homo sapiens_hsa053200.58729816
114Cardiac muscle contraction_Homo sapiens_hsa042600.58503888
115Toxoplasmosis_Homo sapiens_hsa051450.57199513
116African trypanosomiasis_Homo sapiens_hsa051430.57003330
117Sulfur relay system_Homo sapiens_hsa041220.56711287
118Sphingolipid metabolism_Homo sapiens_hsa006000.56406222
119Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.55886742
120Primary immunodeficiency_Homo sapiens_hsa053400.54990387
121Salivary secretion_Homo sapiens_hsa049700.54537743
122Chemical carcinogenesis_Homo sapiens_hsa052040.54104397
123Staphylococcus aureus infection_Homo sapiens_hsa051500.54070391
124Metabolic pathways_Homo sapiens_hsa011000.53915090
125SNARE interactions in vesicular transport_Homo sapiens_hsa041300.53868383
126Rheumatoid arthritis_Homo sapiens_hsa053230.52563367
127Systemic lupus erythematosus_Homo sapiens_hsa053220.51799475
128Fatty acid degradation_Homo sapiens_hsa000710.50681885
129Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.50301245
130T cell receptor signaling pathway_Homo sapiens_hsa046600.48894923
131Renin-angiotensin system_Homo sapiens_hsa046140.48156089
132cGMP-PKG signaling pathway_Homo sapiens_hsa040220.47076143
133Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.46522536
134Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46441409
135Base excision repair_Homo sapiens_hsa034100.46355390
136Hematopoietic cell lineage_Homo sapiens_hsa046400.46123895
137Dopaminergic synapse_Homo sapiens_hsa047280.45580008
138Hedgehog signaling pathway_Homo sapiens_hsa043400.44670784
139Inositol phosphate metabolism_Homo sapiens_hsa005620.44232994
140Malaria_Homo sapiens_hsa051440.42003331
141Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40770156
142Epstein-Barr virus infection_Homo sapiens_hsa051690.40749810
143cAMP signaling pathway_Homo sapiens_hsa040240.39556690
144Collecting duct acid secretion_Homo sapiens_hsa049660.39256678
145Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.38990688
146Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37756201
147Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.37514151
148Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.36749829
149Phosphatidylinositol signaling system_Homo sapiens_hsa040700.35677419
150Thyroid hormone synthesis_Homo sapiens_hsa049180.35029888
151Homologous recombination_Homo sapiens_hsa034400.34970877
152Long-term depression_Homo sapiens_hsa047300.34358125
153Vascular smooth muscle contraction_Homo sapiens_hsa042700.33829467
154Vitamin digestion and absorption_Homo sapiens_hsa049770.33576486
155Cysteine and methionine metabolism_Homo sapiens_hsa002700.32803697
156Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.31000750

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