MORN4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.45015695
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.36550810
3synaptic vesicle docking involved in exocytosis (GO:0016081)5.16375641
4synaptic vesicle exocytosis (GO:0016079)5.13169323
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.06641311
6glutamate secretion (GO:0014047)4.83081433
7regulation of synaptic vesicle exocytosis (GO:2000300)4.64511633
8behavioral response to nicotine (GO:0035095)4.64119232
9vocalization behavior (GO:0071625)4.50872054
10protein localization to synapse (GO:0035418)4.49692886
11neuron cell-cell adhesion (GO:0007158)4.47562902
12pyrimidine nucleobase catabolic process (GO:0006208)4.44786954
13layer formation in cerebral cortex (GO:0021819)4.44366045
14regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.43463602
15locomotory exploration behavior (GO:0035641)4.41954523
16cell migration in hindbrain (GO:0021535)4.23783502
17positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.23567203
18regulation of synapse structural plasticity (GO:0051823)4.11888916
19negative regulation of microtubule polymerization (GO:0031115)4.10042332
20regulation of synaptic vesicle transport (GO:1902803)4.07665677
21positive regulation of synapse maturation (GO:0090129)4.00128143
22regulation of glutamate receptor signaling pathway (GO:1900449)3.99868519
23exploration behavior (GO:0035640)3.84460003
24neurotransmitter secretion (GO:0007269)3.84433501
25neuron recognition (GO:0008038)3.82671875
26regulation of neuronal synaptic plasticity (GO:0048168)3.77180528
27axonal fasciculation (GO:0007413)3.74813661
28response to pheromone (GO:0019236)3.65262583
29neurotransmitter-gated ion channel clustering (GO:0072578)3.62949349
30retinal ganglion cell axon guidance (GO:0031290)3.62125863
31nonmotile primary cilium assembly (GO:0035058)3.61298806
32dendritic spine morphogenesis (GO:0060997)3.59833866
33postsynaptic membrane organization (GO:0001941)3.58432321
34synaptic transmission, glutamatergic (GO:0035249)3.47021486
35neurofilament cytoskeleton organization (GO:0060052)3.46595968
36proline transport (GO:0015824)3.43744935
37regulation of long-term neuronal synaptic plasticity (GO:0048169)3.40254951
38synaptic vesicle endocytosis (GO:0048488)3.39694752
39transmission of nerve impulse (GO:0019226)3.39171591
40regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.34873310
41nucleobase catabolic process (GO:0046113)3.30280034
42adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.29941797
43calcium ion-dependent exocytosis (GO:0017156)3.28262491
44ionotropic glutamate receptor signaling pathway (GO:0035235)3.27954209
45regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.24844130
46negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.22773176
47response to auditory stimulus (GO:0010996)3.22450022
48neuron-neuron synaptic transmission (GO:0007270)3.21414621
49positive regulation of synaptic transmission, GABAergic (GO:0032230)3.20476772
50dendrite morphogenesis (GO:0048813)3.17667916
51auditory behavior (GO:0031223)3.17195102
52behavioral response to ethanol (GO:0048149)3.16891840
53regulation of synapse maturation (GO:0090128)3.13945269
54regulation of neurotransmitter secretion (GO:0046928)3.09924554
55central nervous system projection neuron axonogenesis (GO:0021952)3.09761255
56G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.09374546
57neuronal action potential propagation (GO:0019227)3.07243114
58hippocampus development (GO:0021766)3.07028495
59epithelial cilium movement (GO:0003351)3.06537906
60regulation of NFAT protein import into nucleus (GO:0051532)3.04229724
61positive regulation of membrane potential (GO:0045838)3.01516234
62presynaptic membrane organization (GO:0097090)3.00732958
63neuronal ion channel clustering (GO:0045161)2.99513829
64positive regulation of mitochondrial fission (GO:0090141)2.99373470
65neurotransmitter transport (GO:0006836)2.97402514
66membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.97286455
67innervation (GO:0060384)2.96404074
68negative regulation of dendrite development (GO:2000171)2.95916699
69epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.95240345
70protein localization to cilium (GO:0061512)2.95033845
71negative regulation of synaptic transmission, GABAergic (GO:0032229)2.92808494
72cerebellar Purkinje cell differentiation (GO:0021702)2.91671951
73regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.89627792
74positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.89434713
75dopamine receptor signaling pathway (GO:0007212)2.89313489
76protein complex biogenesis (GO:0070271)2.88994559
77regulation of synaptic plasticity (GO:0048167)2.88823936
78calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.88650064
79sequestering of actin monomers (GO:0042989)2.87218725
80membrane depolarization during action potential (GO:0086010)2.87136133
81regulation of neurotransmitter transport (GO:0051588)2.86733187
82intraciliary transport (GO:0042073)2.86585156
83glutamate receptor signaling pathway (GO:0007215)2.86244374
84activation of protein kinase A activity (GO:0034199)2.83129151
85regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.82432633
86substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.82144168
87substrate-independent telencephalic tangential migration (GO:0021826)2.82144168
88protein-cofactor linkage (GO:0018065)2.80604223
89neuromuscular synaptic transmission (GO:0007274)2.80474416
90regulation of excitatory postsynaptic membrane potential (GO:0060079)2.80161757
91synapse assembly (GO:0007416)2.79681759
92positive regulation of neurotransmitter transport (GO:0051590)2.79426646
93establishment of synaptic vesicle localization (GO:0097480)2.77770365
94synaptic vesicle transport (GO:0048489)2.77770365
95spinal cord association neuron differentiation (GO:0021527)2.76643814
96regulation of cilium movement (GO:0003352)2.76459746
97gamma-aminobutyric acid transport (GO:0015812)2.76434346
98regulation of vesicle fusion (GO:0031338)2.76273554
99presynaptic membrane assembly (GO:0097105)2.75939268
100mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.75504272
101mitochondrial respiratory chain complex I assembly (GO:0032981)2.75504272
102NADH dehydrogenase complex assembly (GO:0010257)2.75504272
103establishment of mitochondrion localization (GO:0051654)2.75491263
104chaperone-mediated protein transport (GO:0072321)2.75338487
105axon extension (GO:0048675)2.75069334
106mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.75053509
107synaptic transmission, cholinergic (GO:0007271)2.74412819
108cell communication by electrical coupling (GO:0010644)2.74388417
109regulation of postsynaptic membrane potential (GO:0060078)2.73749412
110cerebellar Purkinje cell layer development (GO:0021680)2.73094726
111establishment of vesicle localization (GO:0051650)2.72232265
112negative regulation of dendrite morphogenesis (GO:0050774)2.72105009
113short-term memory (GO:0007614)2.72070553
114acrosome reaction (GO:0007340)2.71857066
115neuromuscular process controlling balance (GO:0050885)2.71600797
116membrane hyperpolarization (GO:0060081)2.71447440
117positive regulation of neurotransmitter secretion (GO:0001956)2.71210224
118regulation of neurotransmitter levels (GO:0001505)2.71035386
119regulation of synaptic transmission, glutamatergic (GO:0051966)2.70699770
120negative regulation of cytosolic calcium ion concentration (GO:0051481)2.70299060
121ganglion development (GO:0061548)2.70277557
122regulation of respiratory system process (GO:0044065)2.70068949
123positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.69862321
124dendritic spine organization (GO:0097061)2.69321834
125organelle transport along microtubule (GO:0072384)2.68877550
126positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.68450918
127protein polyglutamylation (GO:0018095)2.67852009
128axon cargo transport (GO:0008088)2.65988756
129mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.65646445
130ATP synthesis coupled proton transport (GO:0015986)2.64481134
131energy coupled proton transport, down electrochemical gradient (GO:0015985)2.64481134
132positive regulation of synapse assembly (GO:0051965)2.62399621
133cerebral cortex radially oriented cell migration (GO:0021799)2.61656374
134establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.61220007
135mitochondrion transport along microtubule (GO:0047497)2.61220007
136olfactory bulb development (GO:0021772)2.60597811
137mitochondrial respiratory chain complex assembly (GO:0033108)2.57914671
138establishment of protein localization to mitochondrial membrane (GO:0090151)2.56900669
139spinal cord development (GO:0021510)2.56504298
140cilium morphogenesis (GO:0060271)2.55515890
141regulation of microtubule-based movement (GO:0060632)2.54342090
142head development (GO:0060322)2.52285781
143startle response (GO:0001964)2.51621666
144glycosphingolipid biosynthetic process (GO:0006688)2.50809997
145adult walking behavior (GO:0007628)2.50657417
146negative regulation of transcription regulatory region DNA binding (GO:2000678)2.49321228
147behavioral response to cocaine (GO:0048148)2.49060881
148forebrain neuron differentiation (GO:0021879)2.45419011
149mechanosensory behavior (GO:0007638)2.43993654
150synapse organization (GO:0050808)2.43079054
151axoneme assembly (GO:0035082)2.42659110
152cilium movement (GO:0003341)2.41616121
153somite development (GO:0061053)2.40293257
154neuron fate determination (GO:0048664)2.39744764
155behavioral defense response (GO:0002209)2.38977412
156behavioral fear response (GO:0001662)2.38977412
157cilium assembly (GO:0042384)2.38593962
158cilium organization (GO:0044782)2.38400610
159cell differentiation in spinal cord (GO:0021515)2.38237170

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.41409878
2GBX2_23144817_ChIP-Seq_PC3_Human3.01333507
3CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.88805302
4NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.85226203
5REST_21632747_ChIP-Seq_MESCs_Mouse2.84315575
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.71316529
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.58004278
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.52241576
9REST_18959480_ChIP-ChIP_MESCs_Mouse2.45789170
10RARB_27405468_Chip-Seq_BRAIN_Mouse2.40300743
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.39258317
12SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.39251426
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.38643566
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.38643566
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.29749050
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.27513520
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.27316410
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.26644537
19ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.26214246
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.14289553
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.13628529
22MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.13609680
23SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.12554342
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.12295333
25SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.09934360
26RBPJ_22232070_ChIP-Seq_NCS_Mouse2.09830501
27MTF2_20144788_ChIP-Seq_MESCs_Mouse2.09826474
28EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.08323542
29DROSHA_22980978_ChIP-Seq_HELA_Human2.00688265
30EED_16625203_ChIP-ChIP_MESCs_Mouse2.00298263
31* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.94942308
32POU3F2_20337985_ChIP-ChIP_501MEL_Human1.88091526
33FUS_26573619_Chip-Seq_HEK293_Human1.83745583
34TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.73725119
35ZFP281_18757296_ChIP-ChIP_E14_Mouse1.68123117
36GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.66030304
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.64872665
38E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.63523193
39TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.61038695
40IKZF1_21737484_ChIP-ChIP_HCT116_Human1.59990906
41ZNF274_21170338_ChIP-Seq_K562_Hela1.59874920
42IRF1_19129219_ChIP-ChIP_H3396_Human1.56070238
43EWS_26573619_Chip-Seq_HEK293_Human1.55161400
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.50003694
45RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.49412162
46TAF15_26573619_Chip-Seq_HEK293_Human1.49310217
47RNF2_27304074_Chip-Seq_NSC_Mouse1.46843320
48BMI1_23680149_ChIP-Seq_NPCS_Mouse1.46839008
49CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.46523249
50PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.44187487
51ERG_21242973_ChIP-ChIP_JURKAT_Human1.43794981
52GABP_17652178_ChIP-ChIP_JURKAT_Human1.42895097
53RING1B_27294783_Chip-Seq_ESCs_Mouse1.42073723
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.37868719
55MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.37044434
56ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.32442892
57CTBP1_25329375_ChIP-Seq_LNCAP_Human1.32236589
58SALL1_21062744_ChIP-ChIP_HESCs_Human1.30475785
59OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.30234955
60EST1_17652178_ChIP-ChIP_JURKAT_Human1.28974948
61POU5F1_16153702_ChIP-ChIP_HESCs_Human1.27743308
62PIAS1_25552417_ChIP-Seq_VCAP_Human1.27565081
63FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.26545196
64MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.25452705
65SMAD4_21799915_ChIP-Seq_A2780_Human1.24715366
66FLI1_27457419_Chip-Seq_LIVER_Mouse1.24705303
67KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.24562213
68SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.24055209
69CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.23367537
70TP53_22573176_ChIP-Seq_HFKS_Human1.23034878
71RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.22975842
72IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.21806796
73CBP_20019798_ChIP-Seq_JUKART_Human1.21806796
74RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.20111883
75RING1B_27294783_Chip-Seq_NPCs_Mouse1.19455377
76PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.17421523
77CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.16995403
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16021951
79KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15091417
80GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.13211311
81SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.13071497
82DNAJC2_21179169_ChIP-ChIP_NT2_Human1.12626743
83SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.11858060
84AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.09941161
85GATA1_26923725_Chip-Seq_HPCs_Mouse1.09393282
86ZFP57_27257070_Chip-Seq_ESCs_Mouse1.09296363
87EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.08465079
88KDM2B_26808549_Chip-Seq_K562_Human1.08309713
89SOX2_21211035_ChIP-Seq_LN229_Gbm1.07840406
90RUNX2_22187159_ChIP-Seq_PCA_Human1.07059192
91KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07058612
92SMAD3_21741376_ChIP-Seq_ESCs_Human1.06124043
93MYC_18940864_ChIP-ChIP_HL60_Human1.06062401
94NR3C1_23031785_ChIP-Seq_PC12_Mouse1.04434987
95TET1_21490601_ChIP-Seq_MESCs_Mouse1.04367226
96P300_19829295_ChIP-Seq_ESCs_Human1.04243429
97PCGF2_27294783_Chip-Seq_ESCs_Mouse1.03606062
98ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.03189439
99ER_23166858_ChIP-Seq_MCF-7_Human1.03046997
100SOX2_16153702_ChIP-ChIP_HESCs_Human1.02154632
101EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.01235375
102ETV2_25802403_ChIP-Seq_MESCs_Mouse1.01208218
103ZFP281_27345836_Chip-Seq_ESCs_Mouse1.00326323
104NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99945208
105AR_19668381_ChIP-Seq_PC3_Human0.99944545
106MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98469152
107IGF1R_20145208_ChIP-Seq_DFB_Human0.98422720
108WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.97679862
109YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97280586
110TOP2B_26459242_ChIP-Seq_MCF-7_Human0.96358391
111CTCF_27219007_Chip-Seq_Bcells_Human0.95764831
112BCAT_22108803_ChIP-Seq_LS180_Human0.94631921
113TAL1_26923725_Chip-Seq_HPCs_Mouse0.94428097
114WT1_25993318_ChIP-Seq_PODOCYTE_Human0.93993606
115P53_22127205_ChIP-Seq_FIBROBLAST_Human0.93496161
116AR_25329375_ChIP-Seq_VCAP_Human0.93441124
117CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93194959
118SMAD3_21741376_ChIP-Seq_EPCs_Human0.93115619
119SOX9_26525672_Chip-Seq_HEART_Mouse0.92678315
120TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.91620318
121SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.91068128
122ELK4_26923725_Chip-Seq_MESODERM_Mouse0.89986914
123AR_21572438_ChIP-Seq_LNCaP_Human0.89052273
124POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.88647395
125TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88647395
126VDR_22108803_ChIP-Seq_LS180_Human0.87579281
127OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.86989807
128SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.86906645
129SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85838526
130TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85350164
131ARNT_22903824_ChIP-Seq_MCF-7_Human0.83772216
132MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.82412858
133STAT3_23295773_ChIP-Seq_U87_Human0.81673846
134EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.81275419
135JUN_21703547_ChIP-Seq_K562_Human0.80821444
136DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.80413250
137TCF4_23295773_ChIP-Seq_U87_Human0.79275116
138AHR_22903824_ChIP-Seq_MCF-7_Human0.77742842

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.24238695
2MP0004270_analgesia3.55882815
3MP0003880_abnormal_central_pattern3.48883535
4MP0003635_abnormal_synaptic_transmissio3.32176913
5MP0005423_abnormal_somatic_nervous2.99823571
6MP0002063_abnormal_learning/memory/cond2.86060449
7MP0001968_abnormal_touch/_nociception2.77841782
8MP0000778_abnormal_nervous_system2.59315673
9MP0002734_abnormal_mechanical_nocicepti2.51969103
10MP0009745_abnormal_behavioral_response2.48316956
11MP0002064_seizures2.40525916
12MP0002572_abnormal_emotion/affect_behav2.30961650
13MP0004858_abnormal_nervous_system2.29036411
14MP0002653_abnormal_ependyma_morphology2.24655995
15MP0002736_abnormal_nociception_after2.24617667
16MP0003122_maternal_imprinting2.24353624
17MP0002735_abnormal_chemical_nociception2.24255231
18MP0001984_abnormal_olfaction2.23983277
19MP0009046_muscle_twitch2.23222211
20MP0006276_abnormal_autonomic_nervous2.19742006
21MP0002184_abnormal_innervation2.17366878
22MP0004811_abnormal_neuron_physiology2.05821380
23MP0002733_abnormal_thermal_nociception2.05661222
24MP0001486_abnormal_startle_reflex1.99686182
25MP0003787_abnormal_imprinting1.99485593
26MP0005645_abnormal_hypothalamus_physiol1.96060939
27MP0002272_abnormal_nervous_system1.94808599
28MP0005394_taste/olfaction_phenotype1.86179395
29MP0005499_abnormal_olfactory_system1.86179395
30MP0002822_catalepsy1.85928614
31MP0000955_abnormal_spinal_cord1.83593507
32MP0002557_abnormal_social/conspecific_i1.81366558
33MP0001970_abnormal_pain_threshold1.80834056
34MP0005410_abnormal_fertilization1.73779321
35MP0005646_abnormal_pituitary_gland1.68560900
36MP0001440_abnormal_grooming_behavior1.66136791
37MP0001529_abnormal_vocalization1.65729283
38MP0008789_abnormal_olfactory_epithelium1.64184287
39MP0002067_abnormal_sensory_capabilities1.61505383
40MP0002882_abnormal_neuron_morphology1.58909302
41MP0003890_abnormal_embryonic-extraembry1.52796982
42MP0009780_abnormal_chondrocyte_physiolo1.50439550
43MP0008569_lethality_at_weaning1.47576558
44MP0005386_behavior/neurological_phenoty1.41856235
45MP0004924_abnormal_behavior1.41856235
46MP0002909_abnormal_adrenal_gland1.40822817
47MP0002152_abnormal_brain_morphology1.38739683
48MP0005253_abnormal_eye_physiology1.30999057
49MP0002751_abnormal_autonomic_nervous1.28834527
50MP0008877_abnormal_DNA_methylation1.26983797
51MP0002066_abnormal_motor_capabilities/c1.26387905
52MP0002837_dystrophic_cardiac_calcinosis1.26208753
53MP0004885_abnormal_endolymph1.25925615
54MP0003123_paternal_imprinting1.24051194
55MP0003861_abnormal_nervous_system1.18846931
56MP0002938_white_spotting1.17952664
57MP0003329_amyloid_beta_deposits1.17885802
58MP0003121_genomic_imprinting1.17525351
59MP0003136_yellow_coat_color1.16500592
60MP0000631_abnormal_neuroendocrine_gland1.16053449
61MP0001501_abnormal_sleep_pattern1.15953808
62MP0003879_abnormal_hair_cell1.15730447
63MP0001905_abnormal_dopamine_level1.15433314
64MP0001502_abnormal_circadian_rhythm1.10763232
65MP0005084_abnormal_gallbladder_morpholo1.10460556
66MP0000569_abnormal_digit_pigmentation1.08087076
67MP0002752_abnormal_somatic_nervous1.06700302
68MP0001293_anophthalmia1.03535906
69MP0003698_abnormal_male_reproductive1.02973054
70MP0003011_delayed_dark_adaptation1.02962905
71MP0005195_abnormal_posterior_eye1.02768566
72MP0000566_synostosis1.01612861
73MP0004233_abnormal_muscle_weight0.99759610
74MP0003938_abnormal_ear_development0.99643200
75MP0004147_increased_porphyrin_level0.98406846
76MP0001986_abnormal_taste_sensitivity0.97590801
77MP0003283_abnormal_digestive_organ0.96534538
78MP0002638_abnormal_pupillary_reflex0.95825057
79MP0004142_abnormal_muscle_tone0.94989975
80MP0001188_hyperpigmentation0.93494432
81MP0000534_abnormal_ureter_morphology0.93407547
82MP0000751_myopathy0.92514083
83MP0010030_abnormal_orbit_morphology0.91802427
84MP0004145_abnormal_muscle_electrophysio0.91389434
85MP0002069_abnormal_eating/drinking_beha0.88435767
86MP0003937_abnormal_limbs/digits/tail_de0.88294762
87MP0002928_abnormal_bile_duct0.86989181
88MP0005187_abnormal_penis_morphology0.86826209
89MP0002163_abnormal_gland_morphology0.86753338
90MP0003942_abnormal_urinary_system0.85706629
91MP0002233_abnormal_nose_morphology0.85212437
92MP0003183_abnormal_peptide_metabolism0.83511165
93MP0008995_early_reproductive_senescence0.82696936
94MP0006292_abnormal_olfactory_placode0.82202717
95MP0002876_abnormal_thyroid_physiology0.81262059
96MP0003631_nervous_system_phenotype0.81033977
97MP0003633_abnormal_nervous_system0.80985854
98MP0003634_abnormal_glial_cell0.80978537
99MP0002229_neurodegeneration0.79543853
100MP0002160_abnormal_reproductive_system0.79052354
101MP0001963_abnormal_hearing_physiology0.77356982
102MP0003119_abnormal_digestive_system0.76857358
103MP0005391_vision/eye_phenotype0.76580901
104MP0001286_abnormal_eye_development0.76536444
105MP0004133_heterotaxia0.75218131
106MP0000647_abnormal_sebaceous_gland0.74015531
107MP0002234_abnormal_pharynx_morphology0.73999279
108MP0001485_abnormal_pinna_reflex0.72761240
109MP0003137_abnormal_impulse_conducting0.72396761
110MP0005623_abnormal_meninges_morphology0.72318661
111MP0003755_abnormal_palate_morphology0.71962563
112MP0001299_abnormal_eye_distance/0.71458480
113MP0002102_abnormal_ear_morphology0.71172535
114MP0008872_abnormal_physiological_respon0.70888498
115MP0000026_abnormal_inner_ear0.68638968
116MP0002081_perinatal_lethality0.67781799
117MP0001348_abnormal_lacrimal_gland0.67716329
118MP0010386_abnormal_urinary_bladder0.66051492
119MP0005248_abnormal_Harderian_gland0.65717207
120MP0005551_abnormal_eye_electrophysiolog0.65607910
121MP0004085_abnormal_heartbeat0.65334926
122MP0001943_abnormal_respiration0.65033700
123MP0004742_abnormal_vestibular_system0.64589956
124MP0000537_abnormal_urethra_morphology0.63396782
125MP0000049_abnormal_middle_ear0.62393027
126MP0008961_abnormal_basal_metabolism0.62368294
127MP0006072_abnormal_retinal_apoptosis0.62216176

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.64815901
2Focal motor seizures (HP:0011153)4.29704481
3Epileptic encephalopathy (HP:0200134)3.75601140
4Focal seizures (HP:0007359)3.73058859
5Limb dystonia (HP:0002451)3.42192561
6Ankle clonus (HP:0011448)3.41542891
7Molar tooth sign on MRI (HP:0002419)3.40458286
8Abnormality of midbrain morphology (HP:0002418)3.40458286
9Pancreatic fibrosis (HP:0100732)3.35210979
10Atonic seizures (HP:0010819)3.26171055
11Visual hallucinations (HP:0002367)3.23792608
12Nephronophthisis (HP:0000090)3.17497789
13True hermaphroditism (HP:0010459)3.14591087
14Pancreatic cysts (HP:0001737)3.14557595
15Abnormality of the lower motor neuron (HP:0002366)3.14537510
16Progressive cerebellar ataxia (HP:0002073)3.14084676
17Febrile seizures (HP:0002373)2.99876076
18Polyphagia (HP:0002591)2.90309493
19Abnormal eating behavior (HP:0100738)2.86581036
20Gait imbalance (HP:0002141)2.84586172
21Amblyopia (HP:0000646)2.80754341
22Supranuclear gaze palsy (HP:0000605)2.73597643
23Failure to thrive in infancy (HP:0001531)2.71788685
24Pheochromocytoma (HP:0002666)2.69852216
25Amyotrophic lateral sclerosis (HP:0007354)2.69224119
26Acute necrotizing encephalopathy (HP:0006965)2.67012403
27Type II lissencephaly (HP:0007260)2.62119158
28Abnormality of the renal medulla (HP:0100957)2.60537035
29Dynein arm defect of respiratory motile cilia (HP:0012255)2.59753815
30Absent/shortened dynein arms (HP:0200106)2.59753815
31Absence seizures (HP:0002121)2.57847132
32Impaired vibration sensation in the lower limbs (HP:0002166)2.57649423
33Pachygyria (HP:0001302)2.54532608
34Action tremor (HP:0002345)2.51223920
35Depression (HP:0000716)2.48417928
36Specific learning disability (HP:0001328)2.47079986
37Mutism (HP:0002300)2.42566804
38Hyperventilation (HP:0002883)2.42299078
39Urinary bladder sphincter dysfunction (HP:0002839)2.40936759
40Hypoplasia of the brainstem (HP:0002365)2.40884305
41Aplasia/Hypoplasia of the brainstem (HP:0007362)2.40884305
42Broad-based gait (HP:0002136)2.40089436
43Truncal ataxia (HP:0002078)2.39254099
44Megalencephaly (HP:0001355)2.37988035
45Abnormal mitochondria in muscle tissue (HP:0008316)2.36156949
46Neuroendocrine neoplasm (HP:0100634)2.36083755
47Drooling (HP:0002307)2.32646655
48Excessive salivation (HP:0003781)2.32646655
49Acute encephalopathy (HP:0006846)2.32316007
50Medial flaring of the eyebrow (HP:0010747)2.32295418
51Congenital primary aphakia (HP:0007707)2.30979839
52Fetal akinesia sequence (HP:0001989)2.30714151
53Lissencephaly (HP:0001339)2.29129200
54Progressive macrocephaly (HP:0004481)2.27354817
55Poor eye contact (HP:0000817)2.26876911
56Urinary urgency (HP:0000012)2.25920586
57Poor coordination (HP:0002370)2.25754936
58Optic nerve hypoplasia (HP:0000609)2.25616943
59Termporal pattern (HP:0011008)2.24309513
60Insidious onset (HP:0003587)2.24309513
61Agitation (HP:0000713)2.23648123
62Generalized tonic-clonic seizures (HP:0002069)2.23111441
63Torticollis (HP:0000473)2.22693541
64Abnormality of the corticospinal tract (HP:0002492)2.22202586
65Dialeptic seizures (HP:0011146)2.21086191
66Anencephaly (HP:0002323)2.18345714
67Nephrogenic diabetes insipidus (HP:0009806)2.17976501
68Hyperglycinemia (HP:0002154)2.17939908
69Mitochondrial inheritance (HP:0001427)2.17752779
70Hemiparesis (HP:0001269)2.16252503
71Spastic gait (HP:0002064)2.15577426
72Insomnia (HP:0100785)2.15441765
73Occipital encephalocele (HP:0002085)2.15188429
74Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.15157786
75Anxiety (HP:0000739)2.14742795
76Epileptiform EEG discharges (HP:0011182)2.13008292
77Chronic hepatic failure (HP:0100626)2.12978255
78Sclerocornea (HP:0000647)2.12810567
79Postural instability (HP:0002172)2.08448562
80Focal dystonia (HP:0004373)2.08293369
81EEG with generalized epileptiform discharges (HP:0011198)2.07863104
82Postaxial hand polydactyly (HP:0001162)2.07777420
83Cystic liver disease (HP:0006706)2.06945196
84Hypsarrhythmia (HP:0002521)2.06607871
85Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.05701224
86Intestinal atresia (HP:0011100)2.05485719
87Poor suck (HP:0002033)2.04443028
88Thyroid-stimulating hormone excess (HP:0002925)2.04363694
89Anosmia (HP:0000458)2.04297059
90Abnormal hair whorl (HP:0010721)2.04208333
91Abnormality of the labia minora (HP:0012880)2.01771626
92Genital tract atresia (HP:0001827)1.99901702
93Genetic anticipation (HP:0003743)1.99801880
94Lower limb muscle weakness (HP:0007340)1.99593307
95Vaginal atresia (HP:0000148)1.99281540
96Abnormal respiratory motile cilium physiology (HP:0012261)1.98155218
97Increased CSF lactate (HP:0002490)1.97514416
98Impaired pain sensation (HP:0007328)1.97385617
99Abnormality of pain sensation (HP:0010832)1.97385617
100Congenital stationary night blindness (HP:0007642)1.97299168
101Abnormal respiratory epithelium morphology (HP:0012253)1.97142507
102Abnormal respiratory motile cilium morphology (HP:0005938)1.97142507
103Septo-optic dysplasia (HP:0100842)1.96562775
104Narrow forehead (HP:0000341)1.95343520
105Pendular nystagmus (HP:0012043)1.94975889
106Impaired social interactions (HP:0000735)1.94899209
107Abnormal social behavior (HP:0012433)1.94899209
108Hypoventilation (HP:0002791)1.94431375
109Sleep apnea (HP:0010535)1.94100026
110Postaxial foot polydactyly (HP:0001830)1.93748353
111Absent speech (HP:0001344)1.91874498
112Pointed chin (HP:0000307)1.90904655
113Cortical dysplasia (HP:0002539)1.90842657
114Gaze-evoked nystagmus (HP:0000640)1.89701235
115Tubular atrophy (HP:0000092)1.88194552
116Hepatoblastoma (HP:0002884)1.87546986
117Broad foot (HP:0001769)1.86479228
118Craniofacial dystonia (HP:0012179)1.86164484
119Impaired smooth pursuit (HP:0007772)1.85418957
120Anophthalmia (HP:0000528)1.83742375
121Oligodactyly (hands) (HP:0001180)1.83606139
122Abnormality of the renal cortex (HP:0011035)1.82380538
123Cerebellar dysplasia (HP:0007033)1.81641412
124Bradykinesia (HP:0002067)1.81123330
125Aplasia/Hypoplasia of the lens (HP:0008063)1.79644992
126Neoplasm of the peripheral nervous system (HP:0100007)1.79267861
127Colon cancer (HP:0003003)1.78915220
128Decreased testicular size (HP:0008734)1.78480392
129Aplasia/Hypoplasia of the tibia (HP:0005772)1.77973884
130Severe muscular hypotonia (HP:0006829)1.77849016
131Rhinitis (HP:0012384)1.77446729
132Hypothermia (HP:0002045)1.77017364
133Shoulder girdle muscle weakness (HP:0003547)1.76296039
134Retinal dysplasia (HP:0007973)1.75668236
135Increased hepatocellular lipid droplets (HP:0006565)1.75436384
136Hepatocellular necrosis (HP:0001404)1.75165547
137Aplasia/Hypoplasia of the tongue (HP:0010295)1.74798639
138Abnormality of ocular smooth pursuit (HP:0000617)1.74629963
139Abnormal ciliary motility (HP:0012262)1.74367912
140Polydipsia (HP:0001959)1.73956319
141Abnormal drinking behavior (HP:0030082)1.73956319
142Inability to walk (HP:0002540)1.73661134
143Aplasia/Hypoplasia of the spleen (HP:0010451)1.73534976
144Generalized hypotonia (HP:0001290)1.72660895
145Renal Fanconi syndrome (HP:0001994)1.72165120
146Short tibia (HP:0005736)1.71846207
147Papilledema (HP:0001085)1.71560910
148Morphological abnormality of the pyramidal tract (HP:0002062)1.71464064
149Progressive inability to walk (HP:0002505)1.71440918
150Stereotypic behavior (HP:0000733)1.70956781
151Dysdiadochokinesis (HP:0002075)1.70943978
152Spastic tetraplegia (HP:0002510)1.69933502
153Clonus (HP:0002169)1.69659217
154Papillary thyroid carcinoma (HP:0002895)1.69034792
155Neoplasm of the heart (HP:0100544)1.68790095

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.56853790
2MAP3K93.02544336
3NTRK32.92525611
4PRKD32.87772274
5MINK12.81678870
6CASK2.54503237
7MAP3K42.43684118
8TRIM282.40558740
9MAP4K22.39627412
10EPHA42.33780894
11MAP2K72.18227594
12DAPK22.17996841
13NTRK22.12228721
14MAPK132.09648747
15PAK62.00196809
16FRK1.99524404
17ADRBK21.95743502
18KSR11.89210015
19PRPF4B1.86506157
20TESK11.85133738
21SIK31.80788856
22MAP3K121.78291217
23DYRK21.68667057
24ARAF1.66194643
25PHKG11.58933181
26PHKG21.58933181
27DAPK11.50768039
28PLK21.42829580
29LATS21.41911517
30UHMK11.41661304
31ICK1.40068881
32CDK51.36150900
33CDK191.35664873
34KSR21.34185331
35CSNK1G11.34038521
36DYRK31.33454430
37CCNB11.30310451
38NTRK11.28563291
39SGK2231.28542515
40SGK4941.28542515
41MAP2K41.27296126
42CAMKK11.25708172
43GRK11.25451114
44GRK51.24244085
45LIMK11.23128564
46WNK41.22022772
47NEK11.20138122
48ERBB31.17275974
49BCKDK1.16736304
50CDK181.14600243
51PDK41.14447514
52PDK31.14447514
53PRKCG1.11052009
54CDK141.10748387
55EPHA31.09018920
56RPS6KA21.09002708
57STK161.06522666
58CDK151.04740351
59ZAK1.03769175
60CSNK1G21.03142367
61LMTK21.02153877
62TYRO31.01969088
63BCR0.98125209
64SGK20.96395817
65CDK11A0.94567931
66PNCK0.90005311
67NUAK10.89664300
68SRPK10.88992287
69STK380.87854195
70BRAF0.86889233
71TESK20.85818839
72INSRR0.85266648
73MAP3K20.84548714
74WNK30.84053238
75TAOK10.82028798
76PAK30.80631110
77TLK10.80214902
78MAPK150.79843589
79SIK20.79220415
80EPHB20.74311014
81MKNK20.73766263
82BRSK10.72937273
83MARK20.72636322
84CSNK1G30.72368138
85DYRK1B0.70677663
86RIPK10.69414642
87PTK2B0.67290825
88EEF2K0.66810576
89DYRK1A0.63781749
90PRKCZ0.63553000
91MAP3K60.62770491
92FGFR20.62032796
93SGK30.61305576
94RET0.60220810
95PKN10.59776919
96CAMKK20.59662300
97CAMK2A0.58960352
98AKT30.57424358
99NME10.55597344
100TSSK60.55040086
101MAPKAPK30.54876083
102PIK3CA0.54690160
103PRKACA0.54668690
104PLK30.52307676
105VRK10.49411210
106CSNK1A10.48462635
107CAMK2B0.47178518
108CSNK1E0.46679313
109STK390.46545894
110CSNK1A1L0.45177541
111MKNK10.44994956
112CSNK1D0.43016081
113CAMK10.42454667
114RAF10.40207096
115PRKCH0.39777539
116PRKAA10.39774358
117STK110.39430482
118PINK10.38346169
119PDK20.38184067
120RPS6KA50.37661114
121RPS6KA40.37416548
122PRKCE0.37012641
123TAOK20.36960260
124ADRBK10.36695532
125PRKCI0.36366688
126STK38L0.35555153
127CAMK2D0.35399250
128PRKG10.35218665
129BMPR1B0.34243969
130MAPK100.34228071
131OXSR10.34036850
132DAPK30.33652067
133CAMK40.33478892
134MAPK90.33360332
135ACVR1B0.32889721
136ROCK10.32513738
137SGK10.32217603
138FER0.31157454
139CDC70.30582064
140TNIK0.29284677
141RPS6KA30.29069342

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.92941034
2Oxidative phosphorylation_Homo sapiens_hsa001903.22605560
3Olfactory transduction_Homo sapiens_hsa047403.04383404
4Nicotine addiction_Homo sapiens_hsa050333.03705852
5Parkinsons disease_Homo sapiens_hsa050122.76170444
6Circadian entrainment_Homo sapiens_hsa047132.61499096
7GABAergic synapse_Homo sapiens_hsa047272.46739684
8Dopaminergic synapse_Homo sapiens_hsa047282.39669273
9Protein export_Homo sapiens_hsa030602.36366591
10Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.33838130
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.33510403
12Amphetamine addiction_Homo sapiens_hsa050312.32772688
13Morphine addiction_Homo sapiens_hsa050322.28887471
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.27284971
15Glutamatergic synapse_Homo sapiens_hsa047242.23529334
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.18555532
17Long-term potentiation_Homo sapiens_hsa047202.12827486
18Insulin secretion_Homo sapiens_hsa049112.03436556
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.02612451
20Collecting duct acid secretion_Homo sapiens_hsa049662.01101370
21Cholinergic synapse_Homo sapiens_hsa047251.94560322
22Alzheimers disease_Homo sapiens_hsa050101.85289900
23Cocaine addiction_Homo sapiens_hsa050301.84603918
24Butanoate metabolism_Homo sapiens_hsa006501.82729223
25Steroid biosynthesis_Homo sapiens_hsa001001.82074445
26Axon guidance_Homo sapiens_hsa043601.71197359
27Taste transduction_Homo sapiens_hsa047421.61776271
28Serotonergic synapse_Homo sapiens_hsa047261.59883236
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.58439357
30Salivary secretion_Homo sapiens_hsa049701.48569862
31Aldosterone synthesis and secretion_Homo sapiens_hsa049251.44750181
32Vibrio cholerae infection_Homo sapiens_hsa051101.44287595
33Gastric acid secretion_Homo sapiens_hsa049711.42587160
34Gap junction_Homo sapiens_hsa045401.41765365
35Oocyte meiosis_Homo sapiens_hsa041141.35825221
36RNA polymerase_Homo sapiens_hsa030201.34371042
37Oxytocin signaling pathway_Homo sapiens_hsa049211.33265960
38Renin secretion_Homo sapiens_hsa049241.30984682
39Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.29771495
40Long-term depression_Homo sapiens_hsa047301.25340705
41Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.23867335
42Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.21547603
43Linoleic acid metabolism_Homo sapiens_hsa005911.20092699
44Propanoate metabolism_Homo sapiens_hsa006401.17676504
45GnRH signaling pathway_Homo sapiens_hsa049121.14051857
46ErbB signaling pathway_Homo sapiens_hsa040121.13410099
47Endometrial cancer_Homo sapiens_hsa052131.12791210
48Calcium signaling pathway_Homo sapiens_hsa040201.12590418
49Phototransduction_Homo sapiens_hsa047441.12386780
50Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.12162103
51Glioma_Homo sapiens_hsa052141.10710066
52Estrogen signaling pathway_Homo sapiens_hsa049151.10474680
53Basal transcription factors_Homo sapiens_hsa030221.08652662
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.08503300
55Melanogenesis_Homo sapiens_hsa049161.07941542
56alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.07859360
57Ether lipid metabolism_Homo sapiens_hsa005651.07323132
58Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.03842239
59Maturity onset diabetes of the young_Homo sapiens_hsa049501.02641784
60Alcoholism_Homo sapiens_hsa050341.01245071
61Colorectal cancer_Homo sapiens_hsa052101.00057442
62Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.97566526
63Type II diabetes mellitus_Homo sapiens_hsa049300.97417514
64Cardiac muscle contraction_Homo sapiens_hsa042600.96918162
65Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.96498570
66cAMP signaling pathway_Homo sapiens_hsa040240.95997352
67Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.95839241
68Peroxisome_Homo sapiens_hsa041460.95049317
69Neurotrophin signaling pathway_Homo sapiens_hsa047220.93574267
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.91367590
71cGMP-PKG signaling pathway_Homo sapiens_hsa040220.91358894
72Nitrogen metabolism_Homo sapiens_hsa009100.88958713
73Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.88786080
74Selenocompound metabolism_Homo sapiens_hsa004500.88072570
75Phosphatidylinositol signaling system_Homo sapiens_hsa040700.86277105
76Fatty acid elongation_Homo sapiens_hsa000620.85410682
77RNA degradation_Homo sapiens_hsa030180.84469969
78Fanconi anemia pathway_Homo sapiens_hsa034600.82722020
79Hedgehog signaling pathway_Homo sapiens_hsa043400.82634051
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.81508550
81Glucagon signaling pathway_Homo sapiens_hsa049220.81036953
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.80989649
83Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.80635573
84Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.78681313
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.78286762
86Tryptophan metabolism_Homo sapiens_hsa003800.78245173
87Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77969653
88Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75017653
89Wnt signaling pathway_Homo sapiens_hsa043100.74949520
90Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71389199
91Ribosome_Homo sapiens_hsa030100.69812305
92Ras signaling pathway_Homo sapiens_hsa040140.68584401
93MAPK signaling pathway_Homo sapiens_hsa040100.66936160
94Endocytosis_Homo sapiens_hsa041440.66586967
95Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.66352831
96Metabolic pathways_Homo sapiens_hsa011000.65638870
97Insulin signaling pathway_Homo sapiens_hsa049100.65172561
98Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.65093449
99Vascular smooth muscle contraction_Homo sapiens_hsa042700.64465908
100Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.64030710
101Hippo signaling pathway_Homo sapiens_hsa043900.64005954
102beta-Alanine metabolism_Homo sapiens_hsa004100.63928978
103Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.62089065
104VEGF signaling pathway_Homo sapiens_hsa043700.61953227
105SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61661180
106mTOR signaling pathway_Homo sapiens_hsa041500.61283356
107Basal cell carcinoma_Homo sapiens_hsa052170.60902672
108Thyroid hormone synthesis_Homo sapiens_hsa049180.60708104
109Phospholipase D signaling pathway_Homo sapiens_hsa040720.60684592
110Carbohydrate digestion and absorption_Homo sapiens_hsa049730.58080543
111Pyruvate metabolism_Homo sapiens_hsa006200.57412643
112Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55701158
113Dorso-ventral axis formation_Homo sapiens_hsa043200.54732048
114Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.53983461
115Renal cell carcinoma_Homo sapiens_hsa052110.53197258
116Caffeine metabolism_Homo sapiens_hsa002320.52989431
117Choline metabolism in cancer_Homo sapiens_hsa052310.51825478
118Rap1 signaling pathway_Homo sapiens_hsa040150.51158477
119Primary bile acid biosynthesis_Homo sapiens_hsa001200.50688701
120Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50579576
121Proteasome_Homo sapiens_hsa030500.49807819
122Purine metabolism_Homo sapiens_hsa002300.49144160
123Cysteine and methionine metabolism_Homo sapiens_hsa002700.49105596
124Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.47982496
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.47657799
126Arginine and proline metabolism_Homo sapiens_hsa003300.47037104
127Tight junction_Homo sapiens_hsa045300.46852899
128Dilated cardiomyopathy_Homo sapiens_hsa054140.46683100
129Longevity regulating pathway - mammal_Homo sapiens_hsa042110.45490613
130Fatty acid metabolism_Homo sapiens_hsa012120.45185816
131Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.44416626
132Melanoma_Homo sapiens_hsa052180.43605079
133mRNA surveillance pathway_Homo sapiens_hsa030150.43262511
134Folate biosynthesis_Homo sapiens_hsa007900.41826571
135Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.41714138
136Sphingolipid signaling pathway_Homo sapiens_hsa040710.40223195
137Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.40148910
138Steroid hormone biosynthesis_Homo sapiens_hsa001400.40078022
139Non-small cell lung cancer_Homo sapiens_hsa052230.39236824
140Circadian rhythm_Homo sapiens_hsa047100.39079380
141Huntingtons disease_Homo sapiens_hsa050160.39031918
142Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38142153
143Regulation of autophagy_Homo sapiens_hsa041400.37926296
144Pyrimidine metabolism_Homo sapiens_hsa002400.37577295
145Sulfur relay system_Homo sapiens_hsa041220.37540047
146Vitamin B6 metabolism_Homo sapiens_hsa007500.37260029
147Homologous recombination_Homo sapiens_hsa034400.36757933
148Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.36231732
149Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.36017704
150Ovarian steroidogenesis_Homo sapiens_hsa049130.35855080
151Chemical carcinogenesis_Homo sapiens_hsa052040.34726856
152Type I diabetes mellitus_Homo sapiens_hsa049400.33283307
153Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.32343637

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