MOV10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of posttranscriptional gene silencing (GO:0060147)4.47885950
2regulation of gene silencing by miRNA (GO:0060964)4.47885950
3regulation of gene silencing by RNA (GO:0060966)4.47885950
4nuclear pore organization (GO:0006999)4.29735186
5folic acid-containing compound biosynthetic process (GO:0009396)4.19127021
6nuclear pore complex assembly (GO:0051292)4.04036438
7response to type I interferon (GO:0034340)3.91172691
8heterochromatin organization (GO:0070828)3.90956159
9type I interferon signaling pathway (GO:0060337)3.86488733
10cellular response to type I interferon (GO:0071357)3.86488733
11formation of translation preinitiation complex (GO:0001731)3.72672255
12mitotic nuclear envelope disassembly (GO:0007077)3.68450672
13DNA unwinding involved in DNA replication (GO:0006268)3.68035407
14positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.58989295
15protein localization to kinetochore (GO:0034501)3.58216963
16DNA replication-dependent nucleosome assembly (GO:0006335)3.55091771
17DNA replication-dependent nucleosome organization (GO:0034723)3.55091771
18pre-miRNA processing (GO:0031054)3.48920785
19regulation of type I interferon-mediated signaling pathway (GO:0060338)3.46547752
20cellular response to interferon-alpha (GO:0035457)3.45719509
21mannose metabolic process (GO:0006013)3.45199661
22regulation of histone H3-K27 methylation (GO:0061085)3.45047066
23positive regulation of Cdc42 GTPase activity (GO:0043089)3.41456429
24somatic diversification of immune receptors via somatic mutation (GO:0002566)3.39400378
25somatic hypermutation of immunoglobulin genes (GO:0016446)3.39400378
26regulation of helicase activity (GO:0051095)3.38869647
27histone H4-K12 acetylation (GO:0043983)3.38359651
28regulation of translational fidelity (GO:0006450)3.37743026
29response to interferon-alpha (GO:0035455)3.36294623
30nuclear envelope disassembly (GO:0051081)3.35712440
31membrane disassembly (GO:0030397)3.35712440
32DNA replication initiation (GO:0006270)3.34573878
33negative regulation of viral release from host cell (GO:1902187)3.34098200
34nucleobase biosynthetic process (GO:0046112)3.32604604
35DNA strand elongation involved in DNA replication (GO:0006271)3.32575814
36COPI coating of Golgi vesicle (GO:0048205)3.26316130
37Golgi transport vesicle coating (GO:0048200)3.26316130
38positive regulation of SMAD protein import into nucleus (GO:0060391)3.15357494
39DNA strand elongation (GO:0022616)3.13771977
40IMP biosynthetic process (GO:0006188)3.11914056
41DNA geometric change (GO:0032392)3.10041550
42DNA duplex unwinding (GO:0032508)3.09815019
43determination of adult lifespan (GO:0008340)3.09640708
44pore complex assembly (GO:0046931)3.05728870
45purine nucleobase biosynthetic process (GO:0009113)2.99687092
46folic acid metabolic process (GO:0046655)2.99547975
47mitotic G1 DNA damage checkpoint (GO:0031571)2.96356359
48chromatin assembly (GO:0031497)2.96173535
49telomere maintenance via semi-conservative replication (GO:0032201)2.96090461
50pinocytosis (GO:0006907)2.95163095
51NIK/NF-kappaB signaling (GO:0038061)2.94742949
52mitotic sister chromatid segregation (GO:0000070)2.93712259
53regulation of gene silencing (GO:0060968)2.92934383
54embryonic process involved in female pregnancy (GO:0060136)2.89587350
55trophectodermal cell differentiation (GO:0001829)2.88744545
56antigen processing and presentation of endogenous antigen (GO:0019883)2.88268271
57tetrahydrofolate metabolic process (GO:0046653)2.87845463
58negative regulation of histone methylation (GO:0031061)2.81833436
59dosage compensation (GO:0007549)2.78735230
60regulation of histone H3-K9 methylation (GO:0051570)2.78200899
61DNA replication checkpoint (GO:0000076)2.75600273
62plasma lipoprotein particle assembly (GO:0034377)2.74653556
63pteridine-containing compound biosynthetic process (GO:0042559)2.74087677
64glycine metabolic process (GO:0006544)2.73514510
65negative regulation of erythrocyte differentiation (GO:0045647)2.72469284
66establishment of apical/basal cell polarity (GO:0035089)2.71602559
67protein localization to chromosome, centromeric region (GO:0071459)2.71483184
68nodal signaling pathway (GO:0038092)2.70946804
69ribosome biogenesis (GO:0042254)2.69797981
70proline biosynthetic process (GO:0006561)2.67391689
71apoptotic process involved in morphogenesis (GO:0060561)2.67338498
72negative regulation of viral genome replication (GO:0045071)2.66835306
73maturation of SSU-rRNA (GO:0030490)2.65768214
74regulation of nuclear cell cycle DNA replication (GO:0033262)2.65497775
75negative regulation of gene silencing (GO:0060969)2.64198636
76peptidyl-glutamic acid carboxylation (GO:0017187)2.64171046
77protein carboxylation (GO:0018214)2.64171046
78positive regulation of histone deacetylation (GO:0031065)2.62518191
79modulation by symbiont of host cellular process (GO:0044068)2.62317390
80regulation of apoptotic process involved in morphogenesis (GO:1902337)2.62024920
81positive regulation of interferon-alpha production (GO:0032727)2.61687286
82regulation of interferon-alpha production (GO:0032647)2.61007535
83mitotic metaphase plate congression (GO:0007080)2.60830026
84nuclear envelope organization (GO:0006998)2.60665972
85mitotic G1/S transition checkpoint (GO:0044819)2.59844142
86IMP metabolic process (GO:0046040)2.59487914
87sister chromatid segregation (GO:0000819)2.59325754
88response to muramyl dipeptide (GO:0032495)2.58624981
89telomere maintenance via recombination (GO:0000722)2.57957892
90mitotic chromosome condensation (GO:0007076)2.57453829
91regulation of SMAD protein import into nucleus (GO:0060390)2.55964091
92urea cycle (GO:0000050)2.55398455
93ribosome assembly (GO:0042255)2.53618966
94negative regulation of fatty acid biosynthetic process (GO:0045717)2.53289240
95proline metabolic process (GO:0006560)2.53222293
96positive regulation of keratinocyte differentiation (GO:0045618)2.52214862
97negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.52007167
98positive regulation of protein import into nucleus, translocation (GO:0033160)2.51459672
99negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.51242016
100regulation of cholesterol homeostasis (GO:2000188)2.50444206
101maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.49236740
102protein-lipid complex assembly (GO:0065005)2.49200601
103positive regulation of chromosome segregation (GO:0051984)2.49014740
104regulation of spindle organization (GO:0090224)2.47622090
105histone H3-K36 demethylation (GO:0070544)2.46970985
106mitotic recombination (GO:0006312)2.45577572
107regulation of integrin activation (GO:0033623)2.45061471
108antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.44268794
109antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.44268794
110GDP-mannose metabolic process (GO:0019673)2.44044691
111response to laminar fluid shear stress (GO:0034616)2.43859289
112urea metabolic process (GO:0019627)2.43607118
113epithelial cell differentiation involved in prostate gland development (GO:0060742)2.43017174
114B cell mediated immunity (GO:0019724)2.42557415
115cellular response to virus (GO:0098586)2.41902336
116negative regulation of defense response to virus (GO:0050687)2.41591518
117regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.41155984
118DNA conformation change (GO:0071103)2.40188790
119regulation of mitotic spindle organization (GO:0060236)2.40140461
120telomere maintenance via telomere lengthening (GO:0010833)2.39812953
121regulation of hippo signaling (GO:0035330)2.38934369
122atrioventricular valve morphogenesis (GO:0003181)2.38555973
123embryonic placenta development (GO:0001892)2.37933046
124histone H4-K5 acetylation (GO:0043981)2.37502442
125histone H4-K8 acetylation (GO:0043982)2.37502442
126pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.37454867
127UMP biosynthetic process (GO:0006222)2.37454867
128pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.37454867
129UMP metabolic process (GO:0046049)2.37454867
130anterior/posterior axis specification, embryo (GO:0008595)2.37100328
131folic acid-containing compound metabolic process (GO:0006760)2.36824043
132phospholipid efflux (GO:0033700)2.36272546
133mitochondrial DNA metabolic process (GO:0032042)2.36237574
134ribosomal small subunit assembly (GO:0000028)2.34787433
135regulation of sister chromatid cohesion (GO:0007063)2.34361292
136histone H2A monoubiquitination (GO:0035518)2.34082005
137L-alpha-amino acid transmembrane transport (GO:1902475)2.33830812
138protein K6-linked ubiquitination (GO:0085020)2.33801652
139modulation by virus of host process (GO:0019054)2.33263028
140regulation of telomere maintenance via telomerase (GO:0032210)2.32137870
141response to peptidoglycan (GO:0032494)2.31977668
142intestinal epithelial cell development (GO:0060576)2.31745952
143activation of Rac GTPase activity (GO:0032863)2.30390992
144basement membrane organization (GO:0071711)2.28641036
145regulation of viral release from host cell (GO:1902186)2.28617120
146glucose 6-phosphate metabolic process (GO:0051156)2.28191408
147very-low-density lipoprotein particle assembly (GO:0034379)2.28110412
148cell-substrate adherens junction assembly (GO:0007045)2.27746292
149focal adhesion assembly (GO:0048041)2.27746292
1503-UTR-mediated mRNA stabilization (GO:0070935)2.27528606
151positive regulation of protein deacetylation (GO:0090312)2.25978766
152pentose-phosphate shunt (GO:0006098)2.25670612
153negative regulation of viral process (GO:0048525)2.24629377
154negative regulation of cytokine production involved in immune response (GO:0002719)2.23719969
155branching involved in mammary gland duct morphogenesis (GO:0060444)2.23501671
156regulation of RIG-I signaling pathway (GO:0039535)2.22667583
157cellular response to exogenous dsRNA (GO:0071360)2.22405220
158modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.21300026
159positive regulation by organism of defense response of other organism involved in symbiotic interact2.21300026
160modulation by symbiont of host immune response (GO:0052553)2.21300026
161positive regulation by symbiont of host defense response (GO:0052509)2.21300026
162modulation by symbiont of host defense response (GO:0052031)2.21300026
163modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.21300026
164glycosphingolipid catabolic process (GO:0046479)2.21138669
165negative regulation of fibrinolysis (GO:0051918)2.19852194
166positive regulation of extracellular matrix organization (GO:1903055)2.19782580
167detection of bacterium (GO:0016045)2.19499573
168planar cell polarity pathway involved in neural tube closure (GO:0090179)2.18550219
169immunoglobulin mediated immune response (GO:0016064)2.17568243
170lipopolysaccharide-mediated signaling pathway (GO:0031663)2.17040894
171positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.16954243
172maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.16896466
173adherens junction assembly (GO:0034333)2.14880121
174response to interferon-beta (GO:0035456)2.14776715
175myeloid dendritic cell differentiation (GO:0043011)2.14234386
176regulation of cytokine secretion involved in immune response (GO:0002739)2.12604651
177interferon-gamma secretion (GO:0072643)2.12248068
178positive regulation of blood vessel endothelial cell migration (GO:0043536)2.12000592
179positive regulation of gamma-delta T cell activation (GO:0046645)2.11971890
180regulation of dendritic cell antigen processing and presentation (GO:0002604)2.10753535
181spliceosomal tri-snRNP complex assembly (GO:0000244)2.09261678
182negative regulation of viral entry into host cell (GO:0046597)2.08882023
183cellular response to epidermal growth factor stimulus (GO:0071364)2.08872159
184activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.08339057
185regulation of glucose import in response to insulin stimulus (GO:2001273)2.07266137
186regulation of extracellular matrix disassembly (GO:0010715)2.06575809
187regulation of T-helper 1 cell differentiation (GO:0045625)2.06347227
188snRNA metabolic process (GO:0016073)2.05970392
189JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.05529005

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.88822813
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.10713916
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.03791345
4KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.74238449
5KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.74238449
6KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.74238449
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.72107956
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.64481652
9SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.56218471
10POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.47955931
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.41980348
12E2F4_17652178_ChIP-ChIP_JURKAT_Human2.33821400
13LXR_22292898_ChIP-Seq_THP-1_Human2.23198661
14STAT3_1855785_ChIP-Seq_MESCs_Mouse2.21443859
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.19377601
16NANOG_18555785_ChIP-Seq_MESCs_Mouse2.09127719
17MYC_22102868_ChIP-Seq_BL_Human2.07395453
18RACK7_27058665_Chip-Seq_MCF-7_Human2.06507874
19MYC_19030024_ChIP-ChIP_MESCs_Mouse2.01053039
20RARG_19884340_ChIP-ChIP_MEFs_Mouse1.99052554
21* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.97144033
22NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.96527609
23NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.94138696
24MYC_18358816_ChIP-ChIP_MESCs_Mouse1.88792036
25* TCF3_18692474_ChIP-Seq_MEFs_Mouse1.84124933
26PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.82878053
27ZNF263_19887448_ChIP-Seq_K562_Human1.82541647
28* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.73396568
29NELFA_20434984_ChIP-Seq_ESCs_Mouse1.71155780
30RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.70293420
31POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.66690660
32* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.65309470
33NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.60633117
34* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.58546554
35* KDM2B_26808549_Chip-Seq_DND41_Human1.57920009
36KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.57216152
37* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.56128676
38ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.53860362
39THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.52287861
40* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.50630751
41MAF_26560356_Chip-Seq_TH2_Human1.50625319
42* ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.50087594
43* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.49859935
44XRN2_22483619_ChIP-Seq_HELA_Human1.47955100
45NCOR1_26117541_ChIP-Seq_K562_Human1.47540682
46* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.47521259
47* VDR_24763502_ChIP-Seq_THP-1_Human1.46230459
48SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.44556835
49* IRF8_22096565_ChIP-ChIP_GC-B_Human1.44263928
50VDR_21846776_ChIP-Seq_THP-1_Human1.44006958
51* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.42706420
52E2F1_21310950_ChIP-Seq_MCF-7_Human1.42562678
53ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.40437100
54AR_21909140_ChIP-Seq_LNCAP_Human1.39559248
55* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.36184825
56CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.35851349
57P68_20966046_ChIP-Seq_HELA_Human1.34753120
58* UTX_26944678_Chip-Seq_JUKART_Human1.34165187
59MYCN_18555785_ChIP-Seq_MESCs_Mouse1.33984599
60KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.31447344
61* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.31351786
62POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.30467732
63ATF3_27146783_Chip-Seq_COLON_Human1.29774021
64* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.29291573
65STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.28998984
66CLOCK_20551151_ChIP-Seq_293T_Human1.26943904
67BRD4_27068464_Chip-Seq_AML-cells_Mouse1.26542457
68* SOX2_18692474_ChIP-Seq_MEFs_Mouse1.26472096
69* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.25549231
70TP63_17297297_ChIP-ChIP_HaCaT_Human1.25186544
71NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.25179706
72E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.25121607
73RUNX1_22412390_ChIP-Seq_EML_Mouse1.24892427
74ETS1_20019798_ChIP-Seq_JURKAT_Human1.24251937
75EST1_17652178_ChIP-ChIP_JURKAT_Human1.23535320
76MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.23516362
77NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.23217590
78ESR2_21235772_ChIP-Seq_MCF-7_Human1.22649722
79SOX2_18555785_ChIP-Seq_MESCs_Mouse1.22057736
80* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.21414528
81TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.21361226
82POU5F1_16518401_ChIP-PET_MESCs_Mouse1.21316511
83RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.21196280
84TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.20841107
85STAT6_21828071_ChIP-Seq_BEAS2B_Human1.19445524
86MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.19155033
87* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.18532977
88PPARA_22158963_ChIP-Seq_LIVER_Mouse1.18421747
89* SA1_27219007_Chip-Seq_ERYTHROID_Human1.18041262
90SMC4_20622854_ChIP-Seq_HELA_Human1.17603530
91GATA1_22383799_ChIP-Seq_G1ME_Mouse1.17561078
92* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.17327842
93TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17174379
94* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.16820016
95KDM5A_27292631_Chip-Seq_BREAST_Human1.15648159
96JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.14119167
97TFEB_21752829_ChIP-Seq_HELA_Human1.14035178
98TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13431334
99* NANOG_18692474_ChIP-Seq_MEFs_Mouse1.13090617
100TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.12974975
101CIITA_25753668_ChIP-Seq_RAJI_Human1.12233200
102* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.11353643
103ELF1_20517297_ChIP-Seq_JURKAT_Human1.11302068
104* IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.10665909
105ZFX_18555785_ChIP-Seq_MESCs_Mouse1.10429853
106ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.09555770
107* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.09535609
108CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.09366116
109CREB1_15753290_ChIP-ChIP_HEK293T_Human1.09354199
110TP53_22127205_ChIP-Seq_IMR90_Human1.08764124
111NANOG_21062744_ChIP-ChIP_HESCs_Human1.08731338
112TET1_21451524_ChIP-Seq_MESCs_Mouse1.07843592
113RUNX1_27514584_Chip-Seq_MCF-7_Human1.07598527
114BCOR_27268052_Chip-Seq_Bcells_Human1.07462178
115* ESR1_15608294_ChIP-ChIP_MCF-7_Human1.07311705
116TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07126847
117CREB1_26743006_Chip-Seq_LNCaP_Human1.06946368
118* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.06747090
119* ELK3_25401928_ChIP-Seq_HUVEC_Human1.05342201
120HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.04983684
121GATA6_25053715_ChIP-Seq_YYC3_Human1.04596010
122TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.03836413
123* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.03180685
124* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.03035839
125CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.02793780
126VDR_23849224_ChIP-Seq_CD4+_Human1.02134229
127SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.01983829
128CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.01900643
129KDM2B_26808549_Chip-Seq_JURKAT_Human1.01569994
130GABP_19822575_ChIP-Seq_HepG2_Human1.01310795
131TCF7_22412390_ChIP-Seq_EML_Mouse1.01180403
132EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01074842
133FOXP3_21729870_ChIP-Seq_TREG_Human1.01038044
134* KDM2B_26808549_Chip-Seq_K562_Human1.00890165
135SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.00464453
136RXR_22158963_ChIP-Seq_LIVER_Mouse1.00286879
137* MAF_26560356_Chip-Seq_TH1_Human1.00204694
138* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.00166005
139* POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.00149088
140YY1_21170310_ChIP-Seq_MESCs_Mouse0.99951696
141RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.99947114
142MYB_26560356_Chip-Seq_TH1_Human0.99666393
143CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.99531262
144* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.99508446
145PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.99496992
146TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.99125228
147CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98644510
148SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.98535657
149* NANOG_18692474_ChIP-Seq_MESCs_Mouse0.98524572
150* IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.98459330
151DCP1A_22483619_ChIP-Seq_HELA_Human0.98248660
152BCL6_27268052_Chip-Seq_Bcells_Human0.97793835
153CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.96613331
154TP63_19390658_ChIP-ChIP_HaCaT_Human0.96419344
155SALL1_21062744_ChIP-ChIP_HESCs_Human0.94423848
156HIF1A_21447827_ChIP-Seq_MCF-7_Human0.93946803
157HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.92979660
158KAP1_27257070_Chip-Seq_ESCs_Mouse0.92743136
159* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.92607280
160ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.91771716
161* IRF8_21731497_ChIP-ChIP_J774_Mouse0.91362512
162KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.91128238
163NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.90840501

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication3.32328063
2MP0010352_gastrointestinal_tract_polyps3.01511498
3MP0004957_abnormal_blastocyst_morpholog2.98368115
4MP0003693_abnormal_embryo_hatching2.79435124
5MP0010094_abnormal_chromosome_stability2.79399699
6MP0003111_abnormal_nucleus_morphology2.75789867
7MP0003806_abnormal_nucleotide_metabolis2.65458564
8MP0005451_abnormal_body_composition2.52380732
9MP0003077_abnormal_cell_cycle2.50289855
10MP0003705_abnormal_hypodermis_morpholog2.39153061
11MP0005058_abnormal_lysosome_morphology2.31749461
12MP0003303_peritoneal_inflammation2.01292696
13MP0010307_abnormal_tumor_latency1.99393289
14MP0009840_abnormal_foam_cell1.90002769
15MP0003300_gastrointestinal_ulcer1.84822746
16MP0005076_abnormal_cell_differentiation1.83886228
17MP0009278_abnormal_bone_marrow1.83348025
18MP0001730_embryonic_growth_arrest1.78963452
19MP0008058_abnormal_DNA_repair1.74574545
20MP0000350_abnormal_cell_proliferation1.70846320
21MP0004264_abnormal_extraembryonic_tissu1.69588930
22MP0005360_urolithiasis1.66637093
23MP0001873_stomach_inflammation1.64705958
24MP0005023_abnormal_wound_healing1.63917752
25MP0002086_abnormal_extraembryonic_tissu1.61603927
26MP0008438_abnormal_cutaneous_collagen1.60754346
27MP0008007_abnormal_cellular_replicative1.60186405
28MP0003566_abnormal_cell_adhesion1.57353989
29MP0001672_abnormal_embryogenesis/_devel1.55882398
30MP0005380_embryogenesis_phenotype1.55882398
31MP0003123_paternal_imprinting1.55706250
32MP0001545_abnormal_hematopoietic_system1.53797988
33MP0005397_hematopoietic_system_phenotyp1.53797988
34MP0004858_abnormal_nervous_system1.51523666
35MP0000490_abnormal_crypts_of1.51032854
36MP0000678_abnormal_parathyroid_gland1.48072093
37MP0004197_abnormal_fetal_growth/weight/1.46334696
38MP0003984_embryonic_growth_retardation1.44135656
39MP0002396_abnormal_hematopoietic_system1.44071126
40MP0002088_abnormal_embryonic_growth/wei1.42707512
41MP0001697_abnormal_embryo_size1.39496615
42MP0000685_abnormal_immune_system1.36105331
43MP0002084_abnormal_developmental_patter1.34768099
44MP0003786_premature_aging1.34186052
45MP0004185_abnormal_adipocyte_glucose1.32981640
46MP0002085_abnormal_embryonic_tissue1.30510281
47MP0008260_abnormal_autophagy1.29721838
48MP0004133_heterotaxia1.27256502
49MP0003172_abnormal_lysosome_physiology1.26660877
50MP0002080_prenatal_lethality1.26134716
51MP0002019_abnormal_tumor_incidence1.24768030
52MP0002653_abnormal_ependyma_morphology1.24161252
53MP0008932_abnormal_embryonic_tissue1.23516155
54MP0002132_abnormal_respiratory_system1.22588211
55MP0010234_abnormal_vibrissa_follicle1.22379197
56MP0002254_reproductive_system_inflammat1.20642052
57MP0009333_abnormal_splenocyte_physiolog1.19819839
58MP0005365_abnormal_bile_salt1.18157078
59MP0004272_abnormal_basement_membrane1.16744409
60MP0003091_abnormal_cell_migration1.16513807
61MP0001661_extended_life_span1.16020285
62MP0005085_abnormal_gallbladder_physiolo1.14569305
63MP0003567_abnormal_fetal_cardiomyocyte1.13522486
64MP0010155_abnormal_intestine_physiology1.12590047
65MP0001293_anophthalmia1.12365950
66MP0002139_abnormal_hepatobiliary_system1.11565625
67MP0003119_abnormal_digestive_system1.11020047
68MP0001835_abnormal_antigen_presentation1.10355377
69MP0002419_abnormal_innate_immunity1.09956386
70MP0005000_abnormal_immune_tolerance1.09643115
71MP0003724_increased_susceptibility_to1.09195497
72MP0003436_decreased_susceptibility_to1.08228239
73MP0003453_abnormal_keratinocyte_physiol1.07194745
74MP0001533_abnormal_skeleton_physiology1.06223709
75MP0005501_abnormal_skin_physiology1.04759839
76MP0000313_abnormal_cell_death1.04614620
77MP0004808_abnormal_hematopoietic_stem1.04541571
78MP0001849_ear_inflammation1.03904006
79MP0005409_darkened_coat_color1.03196987
80MP0002796_impaired_skin_barrier1.03122010
81MP0000689_abnormal_spleen_morphology1.02668934
82MP0003191_abnormal_cellular_cholesterol1.01743301
83MP0001216_abnormal_epidermal_layer1.01695076
84MP0008469_abnormal_protein_level1.00062900
85MP0002722_abnormal_immune_system0.99459254
86MP0002398_abnormal_bone_marrow0.99384857
87MP0003283_abnormal_digestive_organ0.99145235
88MP0005257_abnormal_intraocular_pressure0.99013085
89MP0000858_altered_metastatic_potential0.98699924
90MP0006082_CNS_inflammation0.98456024
91MP0010030_abnormal_orbit_morphology0.98408375
92MP0003183_abnormal_peptide_metabolism0.96982254
93MP0003941_abnormal_skin_development0.94577928
94MP0005266_abnormal_metabolism0.94028790
95MP0001666_abnormal_nutrient_absorption0.93991346
96MP0000477_abnormal_intestine_morphology0.93695138
97MP0002148_abnormal_hypersensitivity_rea0.93658887
98MP0009931_abnormal_skin_appearance0.93613698
99MP0000609_abnormal_liver_physiology0.93517341
100MP0009785_altered_susceptibility_to0.93511006
101MP0000371_diluted_coat_color0.92992975
102MP0003763_abnormal_thymus_physiology0.91247603
103MP0001800_abnormal_humoral_immune0.90924042
104MP0003890_abnormal_embryonic-extraembry0.90888332
105MP0002877_abnormal_melanocyte_morpholog0.90179507
106MP0000598_abnormal_liver_morphology0.89168155
107MP0003186_abnormal_redox_activity0.88832909
108MP0005083_abnormal_biliary_tract0.87780247
109MP0002060_abnormal_skin_morphology0.86867951
110MP0003448_altered_tumor_morphology0.86649821
111MP0001819_abnormal_immune_cell0.86182745
112MP0005666_abnormal_adipose_tissue0.86094364
113MP0002138_abnormal_hepatobiliary_system0.85848725
114MP0001915_intracranial_hemorrhage0.85619104
115MP0009053_abnormal_anal_canal0.85342084
116MP0004947_skin_inflammation0.85143629
117MP0004233_abnormal_muscle_weight0.84649064
118MP0001845_abnormal_inflammatory_respons0.84457588
119MP0002166_altered_tumor_susceptibility0.84139230
120MP0003718_maternal_effect0.84115974
121MP0002420_abnormal_adaptive_immunity0.83751517
122MP0002405_respiratory_system_inflammati0.83647376
123MP0001348_abnormal_lacrimal_gland0.82997378
124MP0000703_abnormal_thymus_morphology0.82412797
125MP0002429_abnormal_blood_cell0.82379904
126MP0002089_abnormal_postnatal_growth/wei0.82288276
127MP0009384_cardiac_valve_regurgitation0.81931792
128MP0008877_abnormal_DNA_methylation0.81872487
129MP0001243_abnormal_dermal_layer0.81019054
130MP0002933_joint_inflammation0.81016529
131MP0005025_abnormal_response_to0.80990556
132MP0002006_tumorigenesis0.80695427
133MP0002249_abnormal_larynx_morphology0.80175594
134MP0005319_abnormal_enzyme/_coenzyme0.76893008
135MP0000716_abnormal_immune_system0.75966272
136MP0002452_abnormal_antigen_presenting0.75473875
137MP0001853_heart_inflammation0.74783447
138MP0005621_abnormal_cell_physiology0.72215243
139MP0003252_abnormal_bile_duct0.70907393
140MP0005387_immune_system_phenotype0.70889742
141MP0001790_abnormal_immune_system0.70889742
142MP0005075_abnormal_melanosome_morpholog0.68312798
143MP0001145_abnormal_male_reproductive0.67164493
144MP0002723_abnormal_immune_serum0.67105157

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.53675203
2Thin bony cortex (HP:0002753)3.53660476
3Selective tooth agenesis (HP:0001592)3.28047236
4Hemorrhage of the eye (HP:0011885)3.17081817
5Deep venous thrombosis (HP:0002625)3.15784811
6Astrocytoma (HP:0009592)3.13577482
7Abnormality of the astrocytes (HP:0100707)3.13577482
8Abnormality of pyrimidine metabolism (HP:0004353)2.84778768
9Agnosia (HP:0010524)2.84493757
10Cervical subluxation (HP:0003308)2.83713269
11Pustule (HP:0200039)2.77724991
12Aplasia/hypoplasia of the humerus (HP:0006507)2.75961288
13Short humerus (HP:0005792)2.75366446
14Medulloblastoma (HP:0002885)2.72175239
15Rhabdomyosarcoma (HP:0002859)2.69468105
16Impulsivity (HP:0100710)2.68548302
17Metaphyseal cupping (HP:0003021)2.66087365
18Rib fusion (HP:0000902)2.62281729
19Flat acetabular roof (HP:0003180)2.61047847
20Abnormality of monocarboxylic acid metabolism (HP:0010996)2.57243401
21Glioma (HP:0009733)2.56099671
22Premature rupture of membranes (HP:0001788)2.53331306
23Basal cell carcinoma (HP:0002671)2.52701339
24Neoplasm of the oral cavity (HP:0100649)2.51429847
25Broad face (HP:0000283)2.49748921
26Malnutrition (HP:0004395)2.49451230
27Breast hypoplasia (HP:0003187)2.49051377
28Systemic lupus erythematosus (HP:0002725)2.48124399
29Neoplasm of striated muscle (HP:0009728)2.48004949
30Colitis (HP:0002583)2.47531500
31Vertebral compression fractures (HP:0002953)2.35100647
32Intestinal fistula (HP:0100819)2.34719024
33Missing ribs (HP:0000921)2.34624899
34Spastic diplegia (HP:0001264)2.33436291
35Rectovaginal fistula (HP:0000143)2.33037576
36Rectal fistula (HP:0100590)2.33037576
37Absent radius (HP:0003974)2.31339496
38Colon cancer (HP:0003003)2.29301826
39Multiple enchondromatosis (HP:0005701)2.28834800
40Biconcave vertebral bodies (HP:0004586)2.25950161
41Shawl scrotum (HP:0000049)2.24438304
42Vaginal fistula (HP:0004320)2.24382662
43Hyperacusis (HP:0010780)2.22087125
44Eczematoid dermatitis (HP:0000976)2.21318624
45Reticulocytopenia (HP:0001896)2.20430213
46Abnormality of complement system (HP:0005339)2.18989924
47Cholecystitis (HP:0001082)2.17724543
48Abnormal gallbladder physiology (HP:0012438)2.17724543
49Abnormality of the anterior horn cell (HP:0006802)2.13553042
50Degeneration of anterior horn cells (HP:0002398)2.13553042
51Hypochromic microcytic anemia (HP:0004840)2.12150036
52Vertebral clefting (HP:0008428)2.11448560
53Chromosomal breakage induced by crosslinking agents (HP:0003221)2.10710985
54Absent forearm bone (HP:0003953)2.08068598
55Aplasia involving forearm bones (HP:0009822)2.08068598
56Disproportionate tall stature (HP:0001519)2.07153840
57Chromsome breakage (HP:0040012)2.05535443
58Birth length less than 3rd percentile (HP:0003561)2.04777377
59Spinal muscular atrophy (HP:0007269)2.04382488
60Absent thumb (HP:0009777)2.03520585
61Polygenic inheritance (HP:0010982)2.02688648
62Delayed epiphyseal ossification (HP:0002663)2.01833729
63Hypobetalipoproteinemia (HP:0003563)2.01536621
64Premature ovarian failure (HP:0008209)2.00977160
65Ulnar bowing (HP:0003031)2.00380253
66Gastrointestinal inflammation (HP:0004386)2.00107460
67Tongue fasciculations (HP:0001308)1.97807935
68Patellar aplasia (HP:0006443)1.97463939
69Abnormality of the lower motor neuron (HP:0002366)1.97262433
70Cerebral aneurysm (HP:0004944)1.96968401
71Reticulocytosis (HP:0001923)1.96922378
72Hand muscle atrophy (HP:0009130)1.95284455
73Deviation of the thumb (HP:0009603)1.94079348
74Amaurosis fugax (HP:0100576)1.94057631
75Complement deficiency (HP:0004431)1.93007839
76Carpal bone hypoplasia (HP:0001498)1.92981999
77Esophageal varix (HP:0002040)1.92315987
78Cupped ribs (HP:0000887)1.92187588
79Abnormality of the labia minora (HP:0012880)1.91877422
80Proximal placement of thumb (HP:0009623)1.91449813
81Pseudobulbar signs (HP:0002200)1.91046351
82Abnormal number of incisors (HP:0011064)1.89873388
83Abnormality of the thoracic spine (HP:0100711)1.89729416
84Hypertensive crisis (HP:0100735)1.88342771
85Muscle fibrillation (HP:0010546)1.87988534
86Supernumerary spleens (HP:0009799)1.86715641
87Ankyloglossia (HP:0010296)1.86586647
88Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.86490735
89Vertebral hypoplasia (HP:0008417)1.86490735
90Trismus (HP:0000211)1.86358985
91Blue sclerae (HP:0000592)1.86247798
92Adenoma sebaceum (HP:0009720)1.85698231
93Angiofibromas (HP:0010615)1.85698231
94Dysostosis multiplex (HP:0000943)1.85689829
95Orchitis (HP:0100796)1.85597313
96Myocardial infarction (HP:0001658)1.85445553
97Long palpebral fissure (HP:0000637)1.84488555
98Loss of speech (HP:0002371)1.84446591
99Elevated alkaline phosphatase (HP:0003155)1.83335160
100Increased IgE level (HP:0003212)1.83010154
101Emphysema (HP:0002097)1.82655688
102Intrahepatic cholestasis (HP:0001406)1.82652723
103Fused cervical vertebrae (HP:0002949)1.82563673
104Mucopolysacchariduria (HP:0008155)1.81903254
105Urinary glycosaminoglycan excretion (HP:0003541)1.81903254
106Vertebral fusion (HP:0002948)1.81589855
107Autoimmune thrombocytopenia (HP:0001973)1.81147108
10811 pairs of ribs (HP:0000878)1.79538230
109Glomerulonephritis (HP:0000099)1.78820607
110Aplasia/Hypoplasia of the patella (HP:0006498)1.78534626
111Abnormality of alkaline phosphatase activity (HP:0004379)1.78365429
112Nasal polyposis (HP:0100582)1.78245671
113J-shaped sella turcica (HP:0002680)1.77888874
114Delayed puberty (HP:0000823)1.77501650
115Joint hemorrhage (HP:0005261)1.76552927
116Abnormality of oral frenula (HP:0000190)1.76180112
117Abnormality of carpal bone ossification (HP:0006257)1.75734955
118Abnormality of the common coagulation pathway (HP:0010990)1.75620403
119Recurrent viral infections (HP:0004429)1.75419909
120Malignant gastrointestinal tract tumors (HP:0006749)1.74831273
121Gastrointestinal carcinoma (HP:0002672)1.74831273
122Premature skin wrinkling (HP:0100678)1.74811102
123Abnormal tarsal ossification (HP:0008369)1.74747036
124Abnormality of macrophages (HP:0004311)1.74221343
125Fragile skin (HP:0001030)1.73981560
126Prominent nose (HP:0000448)1.73885706
127Abnormal foot bone ossification (HP:0010675)1.73749221
128Abnormal ossification of hand bones (HP:0005921)1.73607345
129Interstitial pulmonary disease (HP:0006530)1.73438646
130Abnormality of glycosaminoglycan metabolism (HP:0004371)1.73213151
131Abnormality of mucopolysaccharide metabolism (HP:0011020)1.73213151
132Abnormality of polysaccharide metabolism (HP:0011012)1.73213151
133Abnormal enzyme/coenzyme activity (HP:0012379)1.72484733
134Syringomyelia (HP:0003396)1.72016016
135Spinal cord lesions (HP:0100561)1.72016016
136Entropion (HP:0000621)1.71911287
137Poikiloderma (HP:0001029)1.71588652
138Abnormality of the ileum (HP:0001549)1.71513767
139Abnormality of the fingertips (HP:0001211)1.71467784
140Abnormality of sulfur amino acid metabolism (HP:0004339)1.70758291
141Myositis (HP:0100614)1.69970728
142Myelodysplasia (HP:0002863)1.69911946
143Cheilitis (HP:0100825)1.69846710
144Abnormality of the salivary glands (HP:0010286)1.69765437
145Seborrheic dermatitis (HP:0001051)1.69566379
146Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.69331030
147Gastrointestinal dysmotility (HP:0002579)1.69290949
148Aneurysm (HP:0002617)1.69238390
149Biliary tract neoplasm (HP:0100574)1.68915681
150Ankle contracture (HP:0006466)1.68131802
151Oral leukoplakia (HP:0002745)1.68058692
152Abnormality of the distal phalanges of the toes (HP:0010182)1.67422844
153Inflammation of the large intestine (HP:0002037)1.67209411
154IgA deficiency (HP:0002720)1.66690802
155Abnormality of the nasal mucosa (HP:0000433)1.66116616
156Gastrointestinal infarctions (HP:0005244)1.66014170
157Abdominal situs inversus (HP:0003363)1.65322699
158Abnormality of abdominal situs (HP:0011620)1.65322699
159Natal tooth (HP:0000695)1.65095481
160Meckel diverticulum (HP:0002245)1.64758535
161Neoplasm of the pancreas (HP:0002894)1.64706453
162Peritonitis (HP:0002586)1.64203433
163Thin ribs (HP:0000883)1.64015984
164Squamous cell carcinoma (HP:0002860)1.63915156
165Thoracic kyphosis (HP:0002942)1.63405066
166Xanthomatosis (HP:0000991)1.63014003
167Abdominal distention (HP:0003270)1.62254627
168Abnormality of the peritoneum (HP:0002585)1.62045827
169Thrombocytosis (HP:0001894)1.61750605
170Abnormality of the distal phalanx of the thumb (HP:0009617)1.61682608
171Skull defect (HP:0001362)1.61308994
172Stridor (HP:0010307)1.60818195
173Supernumerary ribs (HP:0005815)1.60382070
174Flattened epiphyses (HP:0003071)1.60108504
175Increased serum ferritin (HP:0003281)1.59761893
176Abnormality of reticulocytes (HP:0004312)1.59212032
177Abnormality of the acetabulum (HP:0003170)1.58945125
178Asymmetry of the thorax (HP:0001555)1.58804796
179Elevated erythrocyte sedimentation rate (HP:0003565)1.58234406
180Protrusio acetabuli (HP:0003179)1.58032741
181Alopecia of scalp (HP:0002293)1.57772422
182Cellulitis (HP:0100658)1.57648345
183Dilatation of the ascending aorta (HP:0005111)1.57266186
184Bone pain (HP:0002653)1.56398121
185Advanced eruption of teeth (HP:0006288)1.56320787
186Progressive external ophthalmoplegia (HP:0000590)1.56062148
187Cafe-au-lait spot (HP:0000957)1.55695045
188Short nail (HP:0001799)1.55346035
189Ileus (HP:0002595)1.54743562
190Persistence of primary teeth (HP:0006335)1.54140151

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.77237542
2SMG13.56760316
3WEE12.87969040
4EPHA22.73900870
5IRAK32.54397271
6SIK12.53046800
7CDC72.27212794
8MST1R2.26598764
9FLT32.24768207
10RPS6KB22.22600917
11EEF2K2.19827776
12NEK22.13882671
13CDK72.03960829
14PRPF4B2.03929432
15MAP3K101.98197362
16TTK1.96872080
17ERN11.95403787
18PKN21.94875166
19STK101.93896720
20NEK11.89587684
21BUB11.74924270
22MAP4K11.72560452
23FGFR41.71329921
24TYK21.70561773
25ICK1.69634380
26CDK41.62306948
27PIM11.45971948
28MATK1.39792051
29PLK11.38879770
30PAK41.37391655
31TESK21.32645515
32JAK31.29204368
33EPHB11.28578848
34GRK61.27643280
35ATR1.26953617
36MAP3K81.26608419
37TRIB31.23671120
38MTOR1.20533267
39DDR21.20308715
40ACVR1B1.19760889
41CDC42BPA1.17901002
42TSSK61.16435627
43BRD41.16393413
44TYRO31.15361513
45CSK1.12876800
46NME21.11817840
47CHEK21.10779202
48PASK1.10682438
49RPS6KA41.09286627
50TGFBR11.08766788
51BMX1.06235659
52KIT1.04165322
53PRKD21.03821246
54RIPK41.03509211
55MAP3K111.03395639
56STK41.02331176
57AKT31.02313712
58MAP3K131.00879483
59ALK0.97840417
60MAPKAPK30.96573894
61IRAK40.95910232
62AURKB0.95694207
63CDK60.95076495
64SCYL20.94107064
65HIPK20.93803988
66CSF1R0.93787085
67PIM20.92333167
68BCKDK0.92069538
69PDGFRA0.90597821
70CHEK10.89764094
71SIK30.86113420
72MAPK110.84940826
73TLK10.84455623
74TBK10.82277269
75LRRK20.81891131
76CHUK0.79005910
77CDK20.76993416
78MAP3K30.76452093
79KSR20.75791644
80RIPK10.74895057
81CDK90.74367531
82STK30.72103390
83IKBKE0.71373279
84MAP3K70.70953370
85MAP2K20.70789501
86PTK60.70156323
87PDPK10.68677864
88ATM0.67414780
89IKBKB0.67222215
90KDR0.64452203
91MARK20.63782575
92BLK0.62244431
93RPS6KL10.61866277
94RPS6KC10.61866277
95PRKCI0.59799213
96MET0.59673397
97LATS10.59143583
98ZAP700.59038733
99RPS6KA20.57913259
100MAP3K10.56792069
101BRSK20.56435788
102AURKA0.54866753
103PAK10.54034375
104PRKG20.53846120
105FGFR30.53608546
106MAP2K60.52832140
107DYRK30.51498581
108MAP2K30.50793175
109AKT20.50746857
110BTK0.50058340
111TGFBR20.49370893
112JAK10.47224515
113EIF2AK10.46657526
114RET0.46118409
115MAPKAPK20.44219514
116RPS6KA60.43439840
117FGR0.43295605
118DYRK1B0.42933745
119CLK10.42506505
120TTN0.41611505
121MELK0.41264726
122TAOK10.41066129
123MAP3K60.40948363
124ZAK0.40779418
125CSNK2A20.40697205
126PDK20.40672727
127MAPK10.40321080
128PLK40.38757321
129PTK20.38466820
130CDK80.38080012
131SIK20.37883266
132TAOK20.37713239
133MAP3K140.37622823
134LCK0.37545103
135PAK20.37415965
136TNK20.36952858
137IRAK10.36864766
138JAK20.36405781
139PDK10.33171004
140NEK90.32901077
141BRSK10.32444433

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.55275213
2Other glycan degradation_Homo sapiens_hsa005113.48555153
3Mismatch repair_Homo sapiens_hsa034303.42898248
4One carbon pool by folate_Homo sapiens_hsa006703.04065657
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.69489995
6Base excision repair_Homo sapiens_hsa034102.42015916
7RNA transport_Homo sapiens_hsa030132.23055046
8Glycosaminoglycan degradation_Homo sapiens_hsa005311.90766232
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.90701793
10Spliceosome_Homo sapiens_hsa030401.89343439
11Folate biosynthesis_Homo sapiens_hsa007901.81711187
12Nucleotide excision repair_Homo sapiens_hsa034201.77066667
13Cell cycle_Homo sapiens_hsa041101.72270422
14Homologous recombination_Homo sapiens_hsa034401.70328025
15Ribosome_Homo sapiens_hsa030101.60847323
16Biosynthesis of amino acids_Homo sapiens_hsa012301.49671827
17Selenocompound metabolism_Homo sapiens_hsa004501.48219136
18Toll-like receptor signaling pathway_Homo sapiens_hsa046201.43418531
19Herpes simplex infection_Homo sapiens_hsa051681.42394915
20Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.42347170
21p53 signaling pathway_Homo sapiens_hsa041151.41883958
222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.41452249
23Arginine biosynthesis_Homo sapiens_hsa002201.31115522
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.28919241
25Osteoclast differentiation_Homo sapiens_hsa043801.26990449
26TNF signaling pathway_Homo sapiens_hsa046681.26712015
27Pyrimidine metabolism_Homo sapiens_hsa002401.23873737
28Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.22583069
29Pancreatic cancer_Homo sapiens_hsa052121.18469072
30Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.17723530
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.15855402
32Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.14289255
33Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.13625723
34Fructose and mannose metabolism_Homo sapiens_hsa000511.13548445
35Antigen processing and presentation_Homo sapiens_hsa046121.13126677
36Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.12126699
37Cyanoamino acid metabolism_Homo sapiens_hsa004601.11701689
38Fanconi anemia pathway_Homo sapiens_hsa034601.11450165
39Non-small cell lung cancer_Homo sapiens_hsa052231.11144618
40Pentose phosphate pathway_Homo sapiens_hsa000301.09971211
41B cell receptor signaling pathway_Homo sapiens_hsa046621.08674341
42mRNA surveillance pathway_Homo sapiens_hsa030151.08338472
43Lysine degradation_Homo sapiens_hsa003101.07512599
44Galactose metabolism_Homo sapiens_hsa000521.07343706
45RNA polymerase_Homo sapiens_hsa030201.06891022
46Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.04766180
47Cysteine and methionine metabolism_Homo sapiens_hsa002701.03475108
48AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.02415013
49Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.99166988
50RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.97890688
51Proteasome_Homo sapiens_hsa030500.96176293
52Notch signaling pathway_Homo sapiens_hsa043300.96111221
53Nitrogen metabolism_Homo sapiens_hsa009100.96073196
54Viral carcinogenesis_Homo sapiens_hsa052030.95779100
55Legionellosis_Homo sapiens_hsa051340.95023047
56Pentose and glucuronate interconversions_Homo sapiens_hsa000400.92678911
57VEGF signaling pathway_Homo sapiens_hsa043700.92530781
58RNA degradation_Homo sapiens_hsa030180.90085939
59Carbon metabolism_Homo sapiens_hsa012000.88250180
60Caffeine metabolism_Homo sapiens_hsa002320.88023779
61Primary bile acid biosynthesis_Homo sapiens_hsa001200.86917842
62Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.86723608
63Non-homologous end-joining_Homo sapiens_hsa034500.86617535
64NF-kappa B signaling pathway_Homo sapiens_hsa040640.86175169
65Allograft rejection_Homo sapiens_hsa053300.86137021
66Staphylococcus aureus infection_Homo sapiens_hsa051500.85909663
67Prion diseases_Homo sapiens_hsa050200.85627280
68Measles_Homo sapiens_hsa051620.85589194
69Influenza A_Homo sapiens_hsa051640.85093760
70Fat digestion and absorption_Homo sapiens_hsa049750.84700781
71Prostate cancer_Homo sapiens_hsa052150.84096123
72Pertussis_Homo sapiens_hsa051330.82949211
73Thyroid cancer_Homo sapiens_hsa052160.80411171
74African trypanosomiasis_Homo sapiens_hsa051430.80215410
75Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.80049385
76Small cell lung cancer_Homo sapiens_hsa052220.79896917
77Sulfur relay system_Homo sapiens_hsa041220.78576528
78Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.78449577
79Lysosome_Homo sapiens_hsa041420.78414952
80Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.78297258
81Insulin resistance_Homo sapiens_hsa049310.78106232
82Epstein-Barr virus infection_Homo sapiens_hsa051690.76943990
83Adipocytokine signaling pathway_Homo sapiens_hsa049200.76226419
84Primary immunodeficiency_Homo sapiens_hsa053400.75020927
85Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.73981254
86Complement and coagulation cascades_Homo sapiens_hsa046100.73310577
87Tryptophan metabolism_Homo sapiens_hsa003800.72444774
88Systemic lupus erythematosus_Homo sapiens_hsa053220.72195212
89Acute myeloid leukemia_Homo sapiens_hsa052210.71583758
90Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71470469
91Tuberculosis_Homo sapiens_hsa051520.71099370
92Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.69499337
93Adherens junction_Homo sapiens_hsa045200.68498298
94Autoimmune thyroid disease_Homo sapiens_hsa053200.68324441
95Malaria_Homo sapiens_hsa051440.67084508
96HTLV-I infection_Homo sapiens_hsa051660.66658474
97Transcriptional misregulation in cancer_Homo sapiens_hsa052020.66635101
98Prolactin signaling pathway_Homo sapiens_hsa049170.66052869
99Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.64659581
100Leukocyte transendothelial migration_Homo sapiens_hsa046700.64425397
101Endometrial cancer_Homo sapiens_hsa052130.64133365
102Amoebiasis_Homo sapiens_hsa051460.63554379
103MicroRNAs in cancer_Homo sapiens_hsa052060.63135272
104Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.61758235
105Apoptosis_Homo sapiens_hsa042100.61693164
106Graft-versus-host disease_Homo sapiens_hsa053320.60984763
107Basal transcription factors_Homo sapiens_hsa030220.60329091
108Glutathione metabolism_Homo sapiens_hsa004800.60276212
109Arginine and proline metabolism_Homo sapiens_hsa003300.59732164
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59153801
111Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58577190
112Leishmaniasis_Homo sapiens_hsa051400.58536153
113mTOR signaling pathway_Homo sapiens_hsa041500.58428556
114Central carbon metabolism in cancer_Homo sapiens_hsa052300.58275438
115Proteoglycans in cancer_Homo sapiens_hsa052050.56526332
116Sphingolipid metabolism_Homo sapiens_hsa006000.56240138
117Bladder cancer_Homo sapiens_hsa052190.55091858
118Phenylalanine metabolism_Homo sapiens_hsa003600.54010310
119Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53923316
120Vitamin digestion and absorption_Homo sapiens_hsa049770.51026433
121Hepatitis B_Homo sapiens_hsa051610.50608685
122N-Glycan biosynthesis_Homo sapiens_hsa005100.49488631
123Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.48521677
124Insulin signaling pathway_Homo sapiens_hsa049100.47976341
125Renin-angiotensin system_Homo sapiens_hsa046140.47467352
126Chronic myeloid leukemia_Homo sapiens_hsa052200.47159155
127TGF-beta signaling pathway_Homo sapiens_hsa043500.46811266
128Shigellosis_Homo sapiens_hsa051310.46077949
129PPAR signaling pathway_Homo sapiens_hsa033200.45306537
130Jak-STAT signaling pathway_Homo sapiens_hsa046300.44907008
131T cell receptor signaling pathway_Homo sapiens_hsa046600.44439702
132Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44249510
133Hippo signaling pathway_Homo sapiens_hsa043900.42751356
134Longevity regulating pathway - mammal_Homo sapiens_hsa042110.42442911
135Intestinal immune network for IgA production_Homo sapiens_hsa046720.42361988
136Fatty acid degradation_Homo sapiens_hsa000710.40726962
137Chemical carcinogenesis_Homo sapiens_hsa052040.39767658
138NOD-like receptor signaling pathway_Homo sapiens_hsa046210.39468692
139Hepatitis C_Homo sapiens_hsa051600.39032520
140Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39023475
141HIF-1 signaling pathway_Homo sapiens_hsa040660.38569524
142Toxoplasmosis_Homo sapiens_hsa051450.38174711
143Viral myocarditis_Homo sapiens_hsa054160.34985041

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »