MPC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.89697202
2L-phenylalanine metabolic process (GO:0006558)5.89697202
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.89048148
4L-phenylalanine catabolic process (GO:0006559)5.89048148
5aromatic amino acid family catabolic process (GO:0009074)5.14102208
6glyoxylate metabolic process (GO:0046487)5.07052526
7cellular ketone body metabolic process (GO:0046950)4.96162633
8triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.95896958
9lysine metabolic process (GO:0006553)4.88680949
10lysine catabolic process (GO:0006554)4.88680949
11regulation of triglyceride catabolic process (GO:0010896)4.59728631
12fatty acid beta-oxidation (GO:0006635)4.59263186
13cysteine metabolic process (GO:0006534)4.58366898
14kynurenine metabolic process (GO:0070189)4.56368314
15tryptophan catabolic process (GO:0006569)4.56140808
16indole-containing compound catabolic process (GO:0042436)4.56140808
17indolalkylamine catabolic process (GO:0046218)4.56140808
18fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.53165993
19short-chain fatty acid metabolic process (GO:0046459)4.47500534
20amino-acid betaine metabolic process (GO:0006577)4.44747859
21regulation of sequestering of triglyceride (GO:0010889)4.37559327
22mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.34546539
23alpha-linolenic acid metabolic process (GO:0036109)4.34186494
24bile acid biosynthetic process (GO:0006699)4.30645331
25fatty acid oxidation (GO:0019395)4.28029428
26ketone body metabolic process (GO:1902224)4.27143427
27sulfur amino acid catabolic process (GO:0000098)4.26685438
28serine family amino acid catabolic process (GO:0009071)4.25733527
29fatty acid catabolic process (GO:0009062)4.24924611
30tryptophan metabolic process (GO:0006568)4.21804638
31lipid oxidation (GO:0034440)4.21033098
32respiratory electron transport chain (GO:0022904)4.17028244
33acetyl-CoA metabolic process (GO:0006084)4.16492659
34branched-chain amino acid catabolic process (GO:0009083)4.11740062
35tricarboxylic acid cycle (GO:0006099)4.09436335
362-oxoglutarate metabolic process (GO:0006103)4.09140147
37electron transport chain (GO:0022900)4.06274635
38aspartate family amino acid catabolic process (GO:0009068)4.06081003
39fatty acid transmembrane transport (GO:1902001)4.04957238
40monocarboxylic acid catabolic process (GO:0072329)3.99318979
41mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.97016739
42homocysteine metabolic process (GO:0050667)3.93893571
43carnitine shuttle (GO:0006853)3.93715405
44carnitine metabolic process (GO:0009437)3.92573885
45alpha-amino acid catabolic process (GO:1901606)3.90541597
46urea cycle (GO:0000050)3.87817169
47urea metabolic process (GO:0019627)3.87817169
48aromatic amino acid family metabolic process (GO:0009072)3.87526220
49high-density lipoprotein particle remodeling (GO:0034375)3.84672368
50ATP synthesis coupled proton transport (GO:0015986)3.79317615
51energy coupled proton transport, down electrochemical gradient (GO:0015985)3.79317615
52phenylpropanoid metabolic process (GO:0009698)3.78047654
53branched-chain amino acid metabolic process (GO:0009081)3.77184290
54cellular amino acid catabolic process (GO:0009063)3.73297889
55triglyceride homeostasis (GO:0070328)3.72096732
56acylglycerol homeostasis (GO:0055090)3.72096732
57bile acid metabolic process (GO:0008206)3.70974327
58nitrogen cycle metabolic process (GO:0071941)3.70950276
59organic acid catabolic process (GO:0016054)3.69272126
60carboxylic acid catabolic process (GO:0046395)3.69272126
61xenobiotic catabolic process (GO:0042178)3.65242030
62biotin metabolic process (GO:0006768)3.64761255
63coenzyme catabolic process (GO:0009109)3.61691057
64NADH metabolic process (GO:0006734)3.58619745
65negative regulation of fibrinolysis (GO:0051918)3.57718851
66plasma lipoprotein particle remodeling (GO:0034369)3.56948878
67protein-lipid complex remodeling (GO:0034368)3.56948878
68macromolecular complex remodeling (GO:0034367)3.56948878
69ethanol oxidation (GO:0006069)3.55386079
70protein complex biogenesis (GO:0070271)3.55066407
71regulation of cholesterol esterification (GO:0010872)3.53867441
72respiratory chain complex IV assembly (GO:0008535)3.53391357
73positive regulation of fatty acid oxidation (GO:0046321)3.52357886
74peptidyl-glutamic acid carboxylation (GO:0017187)3.52231059
75protein carboxylation (GO:0018214)3.52231059
76regulation of fibrinolysis (GO:0051917)3.51595708
77valine metabolic process (GO:0006573)3.50633404
78flavonoid metabolic process (GO:0009812)3.49286778
79complement activation, alternative pathway (GO:0006957)3.48264652
80plasma lipoprotein particle clearance (GO:0034381)3.46053170
81carnitine transport (GO:0015879)3.43864401
82amino-acid betaine transport (GO:0015838)3.43864401
83regulation of protein activation cascade (GO:2000257)3.41289464
84positive regulation of lipid catabolic process (GO:0050996)3.39068205
85succinate metabolic process (GO:0006105)3.38826771
86epoxygenase P450 pathway (GO:0019373)3.37572257
87carnitine transmembrane transport (GO:1902603)3.36837712
88reverse cholesterol transport (GO:0043691)3.34141762
89regulation of fatty acid oxidation (GO:0046320)3.33590331
90positive regulation of fatty acid beta-oxidation (GO:0032000)3.33033146
91drug transmembrane transport (GO:0006855)3.32339188
92tyrosine metabolic process (GO:0006570)3.31277985
93cellular glucuronidation (GO:0052695)3.30676762
94serine family amino acid metabolic process (GO:0009069)3.27434099
95mitochondrial respiratory chain complex assembly (GO:0033108)3.25909368
96oxidative phosphorylation (GO:0006119)3.25553604
97response to mercury ion (GO:0046689)3.25444201
98glutamate metabolic process (GO:0006536)3.25190870
99aldehyde catabolic process (GO:0046185)3.25087333
100S-adenosylmethionine metabolic process (GO:0046500)3.22716712
101cytochrome complex assembly (GO:0017004)3.21248884
102acyl-CoA metabolic process (GO:0006637)3.21056712
103thioester metabolic process (GO:0035383)3.21056712
104benzene-containing compound metabolic process (GO:0042537)3.20879866
105regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.20778653
106drug catabolic process (GO:0042737)3.18624468
107small molecule catabolic process (GO:0044282)3.17582318
108oxaloacetate metabolic process (GO:0006107)3.16690906
109regulation of complement activation (GO:0030449)3.16604607
110amine catabolic process (GO:0009310)3.16602706
111water-soluble vitamin biosynthetic process (GO:0042364)3.14988759
112exogenous drug catabolic process (GO:0042738)3.03040681
113daunorubicin metabolic process (GO:0044597)2.99144616
114polyketide metabolic process (GO:0030638)2.99144616
115doxorubicin metabolic process (GO:0044598)2.99144616
116glutathione derivative metabolic process (GO:1901685)2.98818360
117glutathione derivative biosynthetic process (GO:1901687)2.98818360
118heme metabolic process (GO:0042168)2.98056011
119mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.91190348
120mitochondrial respiratory chain complex I assembly (GO:0032981)2.91190348
121NADH dehydrogenase complex assembly (GO:0010257)2.91190348
122glucuronate metabolic process (GO:0019585)2.90056821
123uronic acid metabolic process (GO:0006063)2.90056821
124regulation of mitochondrial translation (GO:0070129)2.89513135
125cofactor catabolic process (GO:0051187)2.87649743
126positive regulation of cellular amine metabolic process (GO:0033240)2.85450780
127ethanol metabolic process (GO:0006067)2.82161166
128drug metabolic process (GO:0017144)2.78092691
129regulation of oxidative phosphorylation (GO:0002082)2.76585554
130heme biosynthetic process (GO:0006783)2.75718914
131very-low-density lipoprotein particle assembly (GO:0034379)2.74359147
132peroxisome fission (GO:0016559)2.73998633
133primary alcohol metabolic process (GO:0034308)2.67090991
134arginine metabolic process (GO:0006525)2.66791573
135L-methionine salvage (GO:0071267)2.65278831
136L-methionine biosynthetic process (GO:0071265)2.65278831
137amino acid salvage (GO:0043102)2.65278831
138aminoglycoside antibiotic metabolic process (GO:0030647)2.64813834
139heme transport (GO:0015886)2.60740881
140regulation of hexokinase activity (GO:1903299)2.59282718
141regulation of glucokinase activity (GO:0033131)2.59282718
142porphyrin-containing compound metabolic process (GO:0006778)2.59110877
143protein maturation by protein folding (GO:0022417)2.58791335
144proteasome assembly (GO:0043248)2.58558889
145hydrogen ion transmembrane transport (GO:1902600)2.58491330
146cellular aldehyde metabolic process (GO:0006081)2.56152263
147quinone metabolic process (GO:1901661)2.55795646
148oxidative demethylation (GO:0070989)2.55208243

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse9.37540656
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse7.26351255
3RXR_22158963_ChIP-Seq_LIVER_Mouse6.48260314
4PPARA_22158963_ChIP-Seq_LIVER_Mouse5.62361089
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.44329617
6EGR1_23403033_ChIP-Seq_LIVER_Mouse5.00529487
7LXR_22158963_ChIP-Seq_LIVER_Mouse4.96975696
8FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.41295472
9* CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.89456352
10TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.65121793
11ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.99279344
12NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.93680682
13CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.81120929
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.69981469
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.52108713
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.20390258
17IGF1R_20145208_ChIP-Seq_DFB_Human2.10074898
18HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.09068392
19HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.06293286
20EST1_17652178_ChIP-ChIP_JURKAT_Human2.04877337
21E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.04425287
22POU3F2_20337985_ChIP-ChIP_501MEL_Human1.84797020
23CREB1_15753290_ChIP-ChIP_HEK293T_Human1.72380882
24ETS1_20019798_ChIP-Seq_JURKAT_Human1.68347410
25ZNF263_19887448_ChIP-Seq_K562_Human1.54439303
26TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.52905166
27PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51855429
28VDR_23849224_ChIP-Seq_CD4+_Human1.45890118
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.39531942
30STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.37595521
31ELF1_17652178_ChIP-ChIP_JURKAT_Human1.33343053
32HTT_18923047_ChIP-ChIP_STHdh_Human1.32727963
33RARG_19884340_ChIP-ChIP_MEFs_Mouse1.30847851
34CLOCK_20551151_ChIP-Seq_293T_Human1.30624226
35FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.29361141
36PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.26713465
37PIAS1_25552417_ChIP-Seq_VCAP_Human1.26177607
38FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.25270807
39PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.25114413
40ELK1_19687146_ChIP-ChIP_HELA_Human1.22204447
41SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.22090742
42TP53_22573176_ChIP-Seq_HFKS_Human1.21105462
43PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.20554120
44ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.18216789
45FOXA1_27270436_Chip-Seq_PROSTATE_Human1.16865395
46FOXA1_25329375_ChIP-Seq_VCAP_Human1.16865395
47E2F1_18555785_ChIP-Seq_MESCs_Mouse1.16702958
48CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.15978599
49VDR_22108803_ChIP-Seq_LS180_Human1.15701378
50AUTS2_25519132_ChIP-Seq_293T-REX_Human1.11699516
51DCP1A_22483619_ChIP-Seq_HELA_Human1.11062557
52NFE2_27457419_Chip-Seq_LIVER_Mouse1.10480376
53PHF8_20622853_ChIP-Seq_HELA_Human1.10152111
54GATA1_22025678_ChIP-Seq_K562_Human1.09854187
55ZFP57_27257070_Chip-Seq_ESCs_Mouse1.09485287
56HOXB4_20404135_ChIP-ChIP_EML_Mouse1.09468165
57THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.09113148
58SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.07000650
59FOXP3_21729870_ChIP-Seq_TREG_Human1.06823944
60ER_23166858_ChIP-Seq_MCF-7_Human1.06411129
61FOXA2_19822575_ChIP-Seq_HepG2_Human1.06146394
62SUZ12_27294783_Chip-Seq_NPCs_Mouse1.04880353
63FOXA1_25552417_ChIP-Seq_VCAP_Human1.03625749
64AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.02999004
65FOXA1_21572438_ChIP-Seq_LNCaP_Human1.01976798
66HNF4A_19822575_ChIP-Seq_HepG2_Human1.01900450
67TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01831307
68RXRA_24833708_ChIP-Seq_LIVER_Mouse1.01629540
69THAP11_20581084_ChIP-Seq_MESCs_Mouse0.99668971
70KAP1_22055183_ChIP-Seq_ESCs_Mouse0.99423899
71CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.98795882
72HNFA_21074721_ChIP-Seq_CACO-2_Human0.98524357
73CRX_20693478_ChIP-Seq_RETINA_Mouse0.98433674
74ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.98269242
75EZH2_27294783_Chip-Seq_NPCs_Mouse0.98122393
76STAT3_18555785_Chip-Seq_ESCs_Mouse0.98074429
77FLI1_27457419_Chip-Seq_LIVER_Mouse0.96603810
78TBX20_22080862_ChIP-Seq_HEART_Mouse0.96240642
79TBX20_22328084_ChIP-Seq_HEART_Mouse0.96240642
80GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.96047774
81RBPJ_21746931_ChIP-Seq_IB4_Human0.96008286
82CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.95817193
83PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.95364889
84GATA6_21074721_ChIP-Seq_CACO-2_Human0.95270346
85RAD21_21589869_ChIP-Seq_MESCs_Mouse0.95075122
86PADI4_21655091_ChIP-ChIP_MCF-7_Human0.94378398
87PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.94001051
88PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.92383624
89TFEB_21752829_ChIP-Seq_HELA_Human0.92070441
90PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.91445926
91AR_21909140_ChIP-Seq_LNCAP_Human0.90592753
92EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.90445260
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.90390592
94GABP_19822575_ChIP-Seq_HepG2_Human0.89217425
95ZNF274_21170338_ChIP-Seq_K562_Hela0.89130435
96GBX2_23144817_ChIP-Seq_PC3_Human0.88913407
97SOX2_18555785_Chip-Seq_ESCs_Mouse0.88913102
98EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.88168722
99FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.87913156
100P53_22387025_ChIP-Seq_ESCs_Mouse0.87078878
101SRF_21415370_ChIP-Seq_HL-1_Mouse0.86118517
102GATA3_21878914_ChIP-Seq_MCF-7_Human0.86030429
103TAF15_26573619_Chip-Seq_HEK293_Human0.85443647
104SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.84850888
105BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.84531956
106EP300_21415370_ChIP-Seq_HL-1_Mouse0.84439288
107ERG_20517297_ChIP-Seq_VCAP_Human0.82762180
108TAF2_19829295_ChIP-Seq_ESCs_Human0.75650816
109AR_20517297_ChIP-Seq_VCAP_Human0.75264446
110CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.74980199
111PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.74221711
112P53_21459846_ChIP-Seq_SAOS-2_Human0.73366621
113SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.72974065
114GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.70849456
115SOX2_27498859_Chip-Seq_STOMACH_Mouse0.70834202
116EGR1_19032775_ChIP-ChIP_M12_Human0.70660919
117NANOG_20526341_ChIP-Seq_ESCs_Human0.70620931
118ESR1_20079471_ChIP-ChIP_T-47D_Human0.69485786
119BCAT_22108803_ChIP-Seq_LS180_Human0.68336528
120CEBPB_22108803_ChIP-Seq_LS180_Human0.68147667
121STAT1_17558387_ChIP-Seq_HELA_Human0.67300104
122CDX2_19796622_ChIP-Seq_MESCs_Mouse0.66340476
123SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.65649067
124OCT4_20526341_ChIP-Seq_ESCs_Human0.64399572
125SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.64314747
126SOX2_22085726_ChIP-Seq_NPCs_Mouse0.63609135
127RARA_24833708_ChIP-Seq_LIVER_Mouse0.63559350
128ESET_19884257_ChIP-Seq_ESCs_Mouse0.63036671
129PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.62238922
130BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.62145522
131GATA4_25053715_ChIP-Seq_YYC3_Human0.62121171
132FOXH1_21741376_ChIP-Seq_EPCs_Human0.61836171
133NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.61639023
134NRF2_20460467_ChIP-Seq_MEFs_Mouse0.61639023
135CBP_21632823_ChIP-Seq_H3396_Human0.60990198
136BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.59418487
137CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.58954732
138NCOR_22424771_ChIP-Seq_293T_Human0.58139665
139TET1_21451524_ChIP-Seq_MESCs_Mouse0.57246790
140CBP_20019798_ChIP-Seq_JUKART_Human0.57232441
141IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.57232441
142FOXH1_21741376_ChIP-Seq_ESCs_Human0.56834246
143LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.55633623
144ETV2_25802403_ChIP-Seq_MESCs_Mouse0.55325944
145STAT3_1855785_ChIP-Seq_MESCs_Mouse0.54884285
146SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.54638339
147GATA3_21867929_ChIP-Seq_TH1_Mouse0.53143254
148ERA_21632823_ChIP-Seq_H3396_Human0.52743024
149KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.52578870
150AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.51847504
151MYC_19915707_ChIP-ChIP_AK7_Human0.51778897
152MYC_19829295_ChIP-Seq_ESCs_Human0.51744775
153RARB_24833708_ChIP-Seq_LIVER_Mouse0.51493457
154RAC3_21632823_ChIP-Seq_H3396_Human0.51463209
155PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.51211931
156RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.51100292
157BCOR_27268052_Chip-Seq_Bcells_Human0.50928763
158SOX2_19829295_ChIP-Seq_ESCs_Human0.50519735
159NANOG_19829295_ChIP-Seq_ESCs_Human0.50519735
160CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.50392785
161CTCF_27219007_Chip-Seq_Bcells_Human0.50287806
162BCL6_27268052_Chip-Seq_Bcells_Human0.49760065

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system6.31414854
2MP0005360_urolithiasis5.93307692
3MP0005085_abnormal_gallbladder_physiolo4.96798819
4MP0005365_abnormal_bile_salt4.62850127
5MP0008875_abnormal_xenobiotic_pharmacok3.86194580
6MP0003806_abnormal_nucleotide_metabolis3.40344435
7MP0003646_muscle_fatigue3.36567259
8MP0002837_dystrophic_cardiac_calcinosis3.15489181
9MP0003195_calcinosis3.09556487
10MP0005332_abnormal_amino_acid2.91902792
11MP0010329_abnormal_lipoprotein_level2.83787745
12MP0003252_abnormal_bile_duct2.81121358
13MP0005083_abnormal_biliary_tract2.54291996
14MP0006036_abnormal_mitochondrial_physio2.48277870
15MP0009840_abnormal_foam_cell2.46280853
16MP0004130_abnormal_muscle_cell2.19527375
17MP0005670_abnormal_white_adipose2.11308381
18MP0004019_abnormal_vitamin_homeostasis2.04658691
19MP0002118_abnormal_lipid_homeostasis2.02047880
20MP0000372_irregular_coat_pigmentation1.99657000
21MP0005379_endocrine/exocrine_gland_phen1.97400225
22MP0001666_abnormal_nutrient_absorption1.96577429
23MP0005451_abnormal_body_composition1.93439891
24MP0002909_abnormal_adrenal_gland1.90211705
25MP0004215_abnormal_myocardial_fiber1.89470469
26MP0003191_abnormal_cellular_cholesterol1.88478008
27MP0005330_cardiomyopathy1.84229762
28MP0005319_abnormal_enzyme/_coenzyme1.80935598
29MP0009780_abnormal_chondrocyte_physiolo1.79596757
30MP0004084_abnormal_cardiac_muscle1.78791373
31MP0004036_abnormal_muscle_relaxation1.75490228
32MP0005584_abnormal_enzyme/coenzyme_acti1.72657607
33MP0000609_abnormal_liver_physiology1.71015528
34MP0005645_abnormal_hypothalamus_physiol1.70700304
35MP0000751_myopathy1.70614949
36MP0010234_abnormal_vibrissa_follicle1.67957996
37MP0003186_abnormal_redox_activity1.64786960
38MP0002138_abnormal_hepatobiliary_system1.63684189
39MP0005646_abnormal_pituitary_gland1.61889595
40MP0004043_abnormal_pH_regulation1.58554442
41MP0001764_abnormal_homeostasis1.55376491
42MP0000749_muscle_degeneration1.54993905
43MP0009643_abnormal_urine_homeostasis1.52151979
44MP0006035_abnormal_mitochondrial_morpho1.50147482
45MP0005666_abnormal_adipose_tissue1.48613247
46MP0009697_abnormal_copulation1.45211898
47MP0005535_abnormal_body_temperature1.37600503
48MP0010386_abnormal_urinary_bladder1.34403275
49MP0001944_abnormal_pancreas_morphology1.31783574
50MP0002971_abnormal_brown_adipose1.31546175
51MP0005636_abnormal_mineral_homeostasis1.30223606
52MP0002638_abnormal_pupillary_reflex1.30130953
53MP0009046_muscle_twitch1.28508056
54MP0006072_abnormal_retinal_apoptosis1.28059733
55MP0000013_abnormal_adipose_tissue1.26660146
56MP0003656_abnormal_erythrocyte_physiolo1.23948987
57MP0008872_abnormal_physiological_respon1.23913376
58MP0002090_abnormal_vision1.22246884
59MP0004270_analgesia1.20711559
60MP0002972_abnormal_cardiac_muscle1.20287776
61MP0003011_delayed_dark_adaptation1.20244579
62MP0005084_abnormal_gallbladder_morpholo1.19427196
63MP0003879_abnormal_hair_cell1.18741408
64MP0005408_hypopigmentation1.15658173
65MP0005620_abnormal_muscle_contractility1.14713342
66MP0004484_altered_response_of1.14062281
67MP0003868_abnormal_feces_composition1.11512333
68MP0005220_abnormal_exocrine_pancreas1.10640580
69MP0004147_increased_porphyrin_level1.08978125
70MP0002693_abnormal_pancreas_physiology1.07951983
71MP0005551_abnormal_eye_electrophysiolog1.07134394
72MP0008775_abnormal_heart_ventricle1.06979645
73MP0001544_abnormal_cardiovascular_syste1.05775075
74MP0005385_cardiovascular_system_phenoty1.05775075
75MP0002078_abnormal_glucose_homeostasis1.03776349
76MP0004087_abnormal_muscle_fiber1.02799388
77MP0003221_abnormal_cardiomyocyte_apopto1.00732440
78MP0003137_abnormal_impulse_conducting1.00604684
79MP0002269_muscular_atrophy0.99260703
80MP0002332_abnormal_exercise_endurance0.98775844
81MP0002163_abnormal_gland_morphology0.97955639
82MP0001529_abnormal_vocalization0.97648666
83MP0006138_congestive_heart_failure0.96063573
84MP0002876_abnormal_thyroid_physiology0.95844148
85MP0001905_abnormal_dopamine_level0.94829931
86MP0000230_abnormal_systemic_arterial0.93404035
87MP0005334_abnormal_fat_pad0.92491029
88MP0005266_abnormal_metabolism0.92135381
89MP0001756_abnormal_urination0.92003634
90MP0002272_abnormal_nervous_system0.91101103
91MP0001661_extended_life_span0.88934574
92MP0005253_abnormal_eye_physiology0.84514910
93MP0001501_abnormal_sleep_pattern0.84106106
94MP0009745_abnormal_behavioral_response0.84006854
95MP0009642_abnormal_blood_homeostasis0.83254324
96MP0009764_decreased_sensitivity_to0.82577240
97MP0005376_homeostasis/metabolism_phenot0.81626627
98MP0004185_abnormal_adipocyte_glucose0.81299987
99MP0000750_abnormal_muscle_regeneration0.81041707
100MP0000639_abnormal_adrenal_gland0.78568167
101MP0000747_muscle_weakness0.78558307
102MP0002160_abnormal_reproductive_system0.78468220
103MP0005375_adipose_tissue_phenotype0.77835495
104MP0002229_neurodegeneration0.77254628
105MP0005410_abnormal_fertilization0.76984853
106MP0005647_abnormal_sex_gland0.76863408
107MP0002106_abnormal_muscle_physiology0.76538727
108MP0005187_abnormal_penis_morphology0.75982222
109MP0000598_abnormal_liver_morphology0.75536078
110MP0009763_increased_sensitivity_to0.75494926
111MP0001968_abnormal_touch/_nociception0.75390306
112MP0005165_increased_susceptibility_to0.74724852
113MP0008469_abnormal_protein_level0.74047600
114MP0001919_abnormal_reproductive_system0.73891833
115MP0001765_abnormal_ion_homeostasis0.72427505
116MP0005389_reproductive_system_phenotype0.72194132
117MP0002736_abnormal_nociception_after0.71036471
118MP0002822_catalepsy0.69532612
119MP0000604_amyloidosis0.68911032
120MP0010630_abnormal_cardiac_muscle0.68700347
121MP0004924_abnormal_behavior0.67554839
122MP0005386_behavior/neurological_phenoty0.67554839
123MP0002064_seizures0.67543174
124MP0002734_abnormal_mechanical_nocicepti0.67445592
125MP0005448_abnormal_energy_balance0.67257357
126MP0004145_abnormal_muscle_electrophysio0.65691444
127MP0004085_abnormal_heartbeat0.62806200
128MP0005369_muscle_phenotype0.59652341
129MP0000759_abnormal_skeletal_muscle0.57633324
130MP0009115_abnormal_fat_cell0.56643903
131MP0000343_altered_response_to0.56186887
132MP0010368_abnormal_lymphatic_system0.56090145
133MP0003953_abnormal_hormone_level0.56069198
134MP0003329_amyloid_beta_deposits0.55482926
135MP0002136_abnormal_kidney_physiology0.54333702
136MP0001984_abnormal_olfaction0.53877993
137MP0003690_abnormal_glial_cell0.52494751
138MP0003718_maternal_effect0.49215055
139MP0008004_abnormal_stomach_pH0.48264480
140MP0004142_abnormal_muscle_tone0.46645297

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)4.98700932
2Hyperglycinuria (HP:0003108)4.41888665
3Hyperammonemia (HP:0001987)4.29789944
4Abnormality of fatty-acid metabolism (HP:0004359)4.24999485
5Ketosis (HP:0001946)4.23205683
6Xanthomatosis (HP:0000991)4.23140399
7Intrahepatic cholestasis (HP:0001406)4.17522228
8Cerebral edema (HP:0002181)4.17473318
9Hyperglycinemia (HP:0002154)4.16837817
10Hypoglycemic coma (HP:0001325)4.11018240
11Abnormality of serine family amino acid metabolism (HP:0010894)4.10796063
12Abnormality of glycine metabolism (HP:0010895)4.10796063
13Hyperlipoproteinemia (HP:0010980)4.02476956
14Deep venous thrombosis (HP:0002625)4.02358157
15Acute encephalopathy (HP:0006846)4.00016125
16Hepatic necrosis (HP:0002605)3.97595913
17Abnormality of dicarboxylic acid metabolism (HP:0010995)3.94868638
18Dicarboxylic aciduria (HP:0003215)3.94868638
19Ketoacidosis (HP:0001993)3.80207393
20Acute necrotizing encephalopathy (HP:0006965)3.78477389
21Prolonged partial thromboplastin time (HP:0003645)3.73550914
22Abnormal mitochondria in muscle tissue (HP:0008316)3.70899539
23Hypobetalipoproteinemia (HP:0003563)3.58804243
24Abnormality of monocarboxylic acid metabolism (HP:0010996)3.53734058
25Lethargy (HP:0001254)3.49086292
26Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.41856958
27Generalized aminoaciduria (HP:0002909)3.36461713
28Hepatocellular necrosis (HP:0001404)3.35891051
29Myoglobinuria (HP:0002913)3.29131973
30Hypoalphalipoproteinemia (HP:0003233)3.26245917
31Mitochondrial inheritance (HP:0001427)3.25229520
32Abnormality of serum amino acid levels (HP:0003112)3.22581601
33Hypolipoproteinemia (HP:0010981)3.21470883
34Progressive macrocephaly (HP:0004481)3.21151391
35Metabolic acidosis (HP:0001942)3.19738800
36Abnormality of aspartate family amino acid metabolism (HP:0010899)3.08280650
37Increased muscle lipid content (HP:0009058)3.07855065
38Increased CSF lactate (HP:0002490)3.07656526
39Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.05456616
40Gout (HP:0001997)3.02690701
41Abnormality of glutamine family amino acid metabolism (HP:0010902)3.01846825
42Lactic acidosis (HP:0003128)2.99968220
43Exercise-induced myalgia (HP:0003738)2.80706204
44Vomiting (HP:0002013)2.80001861
45Proximal tubulopathy (HP:0000114)2.78697779
46Epidermoid cyst (HP:0200040)2.77932263
47Rhabdomyolysis (HP:0003201)2.77830185
48Complement deficiency (HP:0004431)2.75341638
49Abnormality of urine glucose concentration (HP:0011016)2.75121005
50Glycosuria (HP:0003076)2.75121005
513-Methylglutaconic aciduria (HP:0003535)2.71912174
52Nausea (HP:0002018)2.69575363
53Abnormality of purine metabolism (HP:0004352)2.68716885
54Increased intramyocellular lipid droplets (HP:0012240)2.67475947
55Palpitations (HP:0001962)2.67346244
56Sudden death (HP:0001699)2.66624530
57Joint hemorrhage (HP:0005261)2.65547062
58Abnormality of glycolysis (HP:0004366)2.63980380
59Increased serum pyruvate (HP:0003542)2.63980380
60Abnormality of methionine metabolism (HP:0010901)2.62883907
61Lipid accumulation in hepatocytes (HP:0006561)2.59757802
62Hypothermia (HP:0002045)2.56612418
63Abnormality of sulfur amino acid metabolism (HP:0004339)2.56253966
64Delayed CNS myelination (HP:0002188)2.52868149
65Methylmalonic aciduria (HP:0012120)2.51945191
66Hyperphosphaturia (HP:0003109)2.47846752
67Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.45024859
68Abnormality of alanine metabolism (HP:0010916)2.45024859
69Hyperalaninemia (HP:0003348)2.45024859
70Increased purine levels (HP:0004368)2.42412640
71Hyperuricemia (HP:0002149)2.42412640
72Respiratory failure (HP:0002878)2.40518913
73Abnormality of vitamin metabolism (HP:0100508)2.39226942
74Abnormality of vitamin B metabolism (HP:0004340)2.38808051
75Fat malabsorption (HP:0002630)2.37230546
76Ventricular tachycardia (HP:0004756)2.34021009
77Abnormality of nucleobase metabolism (HP:0010932)2.33447525
78Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.32562867
79Decreased activity of mitochondrial respiratory chain (HP:0008972)2.32562867
80Hyperbilirubinemia (HP:0002904)2.31608700
81Abnormality of the common coagulation pathway (HP:0010990)2.29544355
82Exercise-induced muscle cramps (HP:0003710)2.29329857
83Renal cortical cysts (HP:0000803)2.27644280
84Hypercholesterolemia (HP:0003124)2.22199563
85Increased serum lactate (HP:0002151)2.20757475
86Skin nodule (HP:0200036)2.18566659
87Ragged-red muscle fibers (HP:0003200)2.17509701
88Calf muscle hypertrophy (HP:0008981)2.17224770
89Abnormality of renal resorption (HP:0011038)2.15144224
90Hyperinsulinemic hypoglycemia (HP:0000825)2.15048360
91Cerebral palsy (HP:0100021)2.14263984
92Cholelithiasis (HP:0001081)2.14076459
93Exercise intolerance (HP:0003546)2.13336996
94Steatorrhea (HP:0002570)2.13058769
95Muscle fiber splitting (HP:0003555)2.12909011
96Abnormality of the intrinsic pathway (HP:0010989)2.12096080
97CNS demyelination (HP:0007305)2.10017451
98Muscle hypertrophy of the lower extremities (HP:0008968)2.08690468
99Abnormal gallbladder morphology (HP:0012437)2.07823622
100Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.07374486
101Increased hepatocellular lipid droplets (HP:0006565)2.07272671
102Abnormality of the heme biosynthetic pathway (HP:0010472)2.06999663
103Methylmalonic acidemia (HP:0002912)2.05696701
104Reduced antithrombin III activity (HP:0001976)2.04616378
105Conjugated hyperbilirubinemia (HP:0002908)2.04191491
106Bundle branch block (HP:0011710)2.04017359
107Vacuolated lymphocytes (HP:0001922)2.02124952
108Conjunctival hamartoma (HP:0100780)2.00972305
109Renal Fanconi syndrome (HP:0001994)2.00435946
110Hyperglycemia (HP:0003074)2.00080826
111Syncope (HP:0001279)1.99625059
112Right ventricular cardiomyopathy (HP:0011663)1.97277695
113Vascular calcification (HP:0004934)1.97074024
114Sensorimotor neuropathy (HP:0007141)1.88557791
115Abnormal urine phosphate concentration (HP:0012599)1.83790139
116Abnormality of the anterior horn cell (HP:0006802)1.80603139
117Degeneration of anterior horn cells (HP:0002398)1.80603139
118Type I transferrin isoform profile (HP:0003642)1.78431913
119Insulin-resistant diabetes mellitus (HP:0000831)1.76590546
120Hypoglycemic seizures (HP:0002173)1.76408473
121Abnormality of the vitamin B12 metabolism (HP:0004341)1.75002945
122Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.74857615
123Abnormal protein N-linked glycosylation (HP:0012347)1.74857615
124Abnormal protein glycosylation (HP:0012346)1.74857615
125Abnormal glycosylation (HP:0012345)1.74857615
126Leukodystrophy (HP:0002415)1.73340772
127Abnormal gallbladder physiology (HP:0012438)1.72354493

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.69775812
2PDK44.33052436
3PDK34.33052436
4MST43.31819562
5PINK13.16943690
6MAP3K122.93773123
7PDK22.65763114
8LMTK22.58995005
9OBSCN2.58541703
10MAP4K22.56468129
11MYLK2.46030743
12WNK42.38385859
13NME22.37199697
14PHKG22.35791623
15PHKG12.35791623
16EIF2AK32.31152025
17NME12.16568320
18ACVR1B2.02671949
19TTN2.00677414
20SCYL21.99446076
21PIM21.89831958
22MUSK1.82005195
23TESK11.77802570
24STK38L1.76015343
25INSRR1.75543713
26TIE11.69973002
27STK391.65585585
28SIK11.62512758
29TLK11.58092623
30FER1.57658647
31CSNK1G31.47251848
32PIK3CG1.47183197
33NUAK11.46833533
34ERN11.46047550
35FGFR41.41813858
36MAP3K41.34748985
37PRKAA21.33687986
38STK161.32855392
39ERBB31.32420556
40CSNK1G21.31604287
41CSNK1G11.31597317
42PIK3CA1.31499731
43PLK21.28183783
44OXSR11.25594455
45TRIB31.25008729
46BMPR1B1.22768241
47MAP2K41.20879155
48MST1R1.19650767
49ARAF1.19172196
50LIMK11.16927490
51MAPKAPK31.15057098
52STK241.12008409
53IRAK31.11962798
54GRK71.08670454
55CAMK2G1.08072563
56WNK31.07085741
57AKT31.06597113
58ABL21.05655234
59ADRBK21.04048984
60PRKAA11.02804925
61MAPK121.02767776
62CCNB11.00636976
63FRK1.00546065
64CSNK1A1L0.99833542
65TRIM280.97583387
66PKN20.94922930
67CAMK2D0.91999766
68MAPK110.91849375
69VRK10.91755620
70IRAK10.90527076
71NEK90.89520019
72NTRK30.89459706
73MAP3K70.88293950
74PLK40.88080741
75KDR0.86264137
76DAPK10.84991716
77PDPK10.84426194
78MAP2K60.82792783
79PRKD30.81870525
80MINK10.81471220
81VRK20.79473915
82NEK10.78706920
83STK380.77722490
84PRKCI0.77385382
85TNK20.75329943
86TAOK20.75086988
87CASK0.74098848
88PAK30.73799692
89BMPR20.73745560
90MAPK130.73125926
91RPS6KA50.71025095
92MAP3K30.69498028
93CAMKK20.66815523
94PDK10.66785592
95MAP3K110.65677515
96PRKACG0.63849392
97MAP3K50.63152483
98MAP2K70.62816114
99MAP2K30.62461734
100CAMK2A0.61916510
101EPHA30.61003720
102DAPK20.59356861
103EPHA40.58178636
104BCR0.58028915
105ERBB40.55366221
106SGK2230.54793717
107SGK4940.54793717
108TYK20.53972391
109FLT30.52696582
110RAF10.52326431
111PRKACA0.52285503
112TESK20.52248328
113CSNK1A10.51744726
114PKN10.51230172
115MAPK40.51159909
116MAP3K20.50995637
117PTK2B0.49177166
118PLK30.47398992
119TAOK30.47155355
120DAPK30.46976272
121BRAF0.46440335
122CSNK2A20.44066865
123PRKD10.43762397
124GRK50.43427445
125PRKG10.43346431
126PBK0.43188833
127PRKCZ0.42636752
128BUB10.42287820
129PRKG20.42228093
130PRKCQ0.42188247
131ZAK0.42138067
132CAMK1D0.41764328
133JAK20.38009646
134CSNK2A10.37053550
135MAP2K10.36909739
136BRSK20.36383924
137PRKCG0.36381707
138GRK10.35228272
139CAMK10.34059202
140FGFR20.33327572
141DYRK30.31088688
142GSK3A0.30628036
143PRKCA0.30531648
144CAMK2B0.30429856
145PRKACB0.30028852
146TBK10.29959514
147EIF2AK10.28845299
148CAMK40.28235223
149PRKCE0.26851239
150ILK0.25455730
151IRAK20.25361421
152MAP3K10.24275980
153AKT20.22046912
154SGK20.21801904
155JAK10.21031743
156DYRK1B0.20389461

Predicted pathways (KEGG)

RankGene SetZ-score
1Propanoate metabolism_Homo sapiens_hsa006403.21381295
2Primary bile acid biosynthesis_Homo sapiens_hsa001203.08404076
3Fatty acid degradation_Homo sapiens_hsa000713.01202740
4Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.99509050
5Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.98410204
6Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.81126115
7Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.67176153
8Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.44008540
9Butanoate metabolism_Homo sapiens_hsa006502.42330025
102-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.35090463
11Fatty acid metabolism_Homo sapiens_hsa012122.34835115
12Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.33102748
13Arginine biosynthesis_Homo sapiens_hsa002202.26412842
14Oxidative phosphorylation_Homo sapiens_hsa001902.25274866
15Nitrogen metabolism_Homo sapiens_hsa009102.25233122
16Tryptophan metabolism_Homo sapiens_hsa003802.18784221
17Peroxisome_Homo sapiens_hsa041462.18160586
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.16316912
19Pyruvate metabolism_Homo sapiens_hsa006202.10545732
20Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.06787959
21PPAR signaling pathway_Homo sapiens_hsa033202.06004473
22Parkinsons disease_Homo sapiens_hsa050122.01875926
23Fatty acid elongation_Homo sapiens_hsa000621.87532038
24Pentose and glucuronate interconversions_Homo sapiens_hsa000401.86652722
25Carbon metabolism_Homo sapiens_hsa012001.86039809
26Sulfur metabolism_Homo sapiens_hsa009201.73342064
27beta-Alanine metabolism_Homo sapiens_hsa004101.72400449
28Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.67554599
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.63650989
30Complement and coagulation cascades_Homo sapiens_hsa046101.63133113
31Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.56825839
32Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.49407803
33Chemical carcinogenesis_Homo sapiens_hsa052041.47892240
34Alzheimers disease_Homo sapiens_hsa050101.46681899
35Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.37332887
36Histidine metabolism_Homo sapiens_hsa003401.36098000
37Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.29010444
38Steroid hormone biosynthesis_Homo sapiens_hsa001401.28141291
39Huntingtons disease_Homo sapiens_hsa050161.26355917
40Cardiac muscle contraction_Homo sapiens_hsa042601.24495373
41Starch and sucrose metabolism_Homo sapiens_hsa005001.22649082
42Drug metabolism - other enzymes_Homo sapiens_hsa009831.20914128
43Vitamin B6 metabolism_Homo sapiens_hsa007501.20876199
44Phenylalanine metabolism_Homo sapiens_hsa003601.20194030
45Retinol metabolism_Homo sapiens_hsa008301.19816012
46Folate biosynthesis_Homo sapiens_hsa007901.19740212
47Biosynthesis of amino acids_Homo sapiens_hsa012301.19352156
48Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.16463210
49Caffeine metabolism_Homo sapiens_hsa002321.15094731
50Bile secretion_Homo sapiens_hsa049761.12353185
51Cysteine and methionine metabolism_Homo sapiens_hsa002701.11183211
52Fat digestion and absorption_Homo sapiens_hsa049751.05817004
53Selenocompound metabolism_Homo sapiens_hsa004501.05296355
54Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.04732170
55Tyrosine metabolism_Homo sapiens_hsa003501.03248480
56Arginine and proline metabolism_Homo sapiens_hsa003301.03156884
57Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.00200600
58Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.99916035
59Sulfur relay system_Homo sapiens_hsa041220.98493681
60Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.91838558
61Fatty acid biosynthesis_Homo sapiens_hsa000610.90907413
62Staphylococcus aureus infection_Homo sapiens_hsa051500.88856084
63Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87300464
64Glycerolipid metabolism_Homo sapiens_hsa005610.83670419
65Glutathione metabolism_Homo sapiens_hsa004800.78908755
66ABC transporters_Homo sapiens_hsa020100.78057803
67Metabolic pathways_Homo sapiens_hsa011000.76638451
68Pentose phosphate pathway_Homo sapiens_hsa000300.74993577
69Cyanoamino acid metabolism_Homo sapiens_hsa004600.74572924
70Vitamin digestion and absorption_Homo sapiens_hsa049770.72034329
71One carbon pool by folate_Homo sapiens_hsa006700.69149748
72Steroid biosynthesis_Homo sapiens_hsa001000.61182887
73Maturity onset diabetes of the young_Homo sapiens_hsa049500.54340991
74Fructose and mannose metabolism_Homo sapiens_hsa000510.53329543
75Sphingolipid metabolism_Homo sapiens_hsa006000.50863740
76Renin-angiotensin system_Homo sapiens_hsa046140.48959133
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.48203867
78Synaptic vesicle cycle_Homo sapiens_hsa047210.46398377
79Linoleic acid metabolism_Homo sapiens_hsa005910.43011652
80Vibrio cholerae infection_Homo sapiens_hsa051100.42427361
81RNA polymerase_Homo sapiens_hsa030200.42387331
82Circadian rhythm_Homo sapiens_hsa047100.41174040
83Adipocytokine signaling pathway_Homo sapiens_hsa049200.40456669
84Insulin secretion_Homo sapiens_hsa049110.40088548
85SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39602204
86Galactose metabolism_Homo sapiens_hsa000520.39363523
87Lysine degradation_Homo sapiens_hsa003100.38199987
88Other glycan degradation_Homo sapiens_hsa005110.35853889
89Pyrimidine metabolism_Homo sapiens_hsa002400.35267336
90Glycerophospholipid metabolism_Homo sapiens_hsa005640.34767224
91Glycosaminoglycan degradation_Homo sapiens_hsa005310.34184464
92Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.33817837
93N-Glycan biosynthesis_Homo sapiens_hsa005100.33429849
94Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32142439
95Glucagon signaling pathway_Homo sapiens_hsa049220.32059493
96Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.27704775
97Insulin resistance_Homo sapiens_hsa049310.24299733
98Arachidonic acid metabolism_Homo sapiens_hsa005900.17821878
99AMPK signaling pathway_Homo sapiens_hsa041520.17671241
100Regulation of autophagy_Homo sapiens_hsa041400.16677428
101Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.12330406
102Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.07138310
103Dilated cardiomyopathy_Homo sapiens_hsa054140.05739875
104Insulin signaling pathway_Homo sapiens_hsa049100.03464478
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.00612445
106Purine metabolism_Homo sapiens_hsa00230-0.1340238
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923-0.1311362
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014-0.1310129
109Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.1229043
110Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0985615
111Protein export_Homo sapiens_hsa03060-0.0849591
112Ether lipid metabolism_Homo sapiens_hsa00565-0.0822750
113Collecting duct acid secretion_Homo sapiens_hsa04966-0.0704734
114Proteasome_Homo sapiens_hsa03050-0.0673447
115Mineral absorption_Homo sapiens_hsa04978-0.0601729
116Prion diseases_Homo sapiens_hsa05020-0.0331549

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