MPP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.36637586
2regulation of short-term neuronal synaptic plasticity (GO:0048172)6.33241496
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.82581494
4synaptic vesicle exocytosis (GO:0016079)5.70712363
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.54087297
6locomotory exploration behavior (GO:0035641)5.51850855
7synaptic vesicle docking involved in exocytosis (GO:0016081)5.34025063
8regulation of synaptic vesicle exocytosis (GO:2000300)5.27965087
9glutamate secretion (GO:0014047)5.26956227
10vocalization behavior (GO:0071625)5.15312585
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.00276496
12protein localization to synapse (GO:0035418)4.74919871
13regulation of glutamate receptor signaling pathway (GO:1900449)4.64793838
14regulation of synaptic vesicle transport (GO:1902803)4.59591307
15cellular potassium ion homeostasis (GO:0030007)4.45769980
16regulation of neuronal synaptic plasticity (GO:0048168)4.35228383
17neurotransmitter secretion (GO:0007269)4.29453471
18exploration behavior (GO:0035640)4.25138594
19neuron cell-cell adhesion (GO:0007158)4.24837384
20regulation of synapse structural plasticity (GO:0051823)4.22878233
21presynaptic membrane assembly (GO:0097105)4.21402227
22presynaptic membrane organization (GO:0097090)4.16816159
23ionotropic glutamate receptor signaling pathway (GO:0035235)4.15540826
24sodium ion export (GO:0071436)4.14432626
25regulation of long-term neuronal synaptic plasticity (GO:0048169)4.14068591
26layer formation in cerebral cortex (GO:0021819)4.08169268
27synaptic transmission, glutamatergic (GO:0035249)3.96234738
28dendritic spine morphogenesis (GO:0060997)3.95741825
29neurotransmitter-gated ion channel clustering (GO:0072578)3.95445534
30pyrimidine nucleobase catabolic process (GO:0006208)3.93736977
31neuronal action potential propagation (GO:0019227)3.93289995
32regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.92536962
33glutamate receptor signaling pathway (GO:0007215)3.90069959
34positive regulation of synapse maturation (GO:0090129)3.88634308
35synaptic vesicle endocytosis (GO:0048488)3.80440411
36neuron-neuron synaptic transmission (GO:0007270)3.79051877
37long-term memory (GO:0007616)3.77095807
38regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.76347614
39membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.76071987
40positive regulation of membrane potential (GO:0045838)3.72736344
41establishment of mitochondrion localization (GO:0051654)3.63224255
42regulation of excitatory postsynaptic membrane potential (GO:0060079)3.62002909
43neurotransmitter transport (GO:0006836)3.57187503
44gamma-aminobutyric acid signaling pathway (GO:0007214)3.56227842
45cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.54957058
46regulation of neurotransmitter secretion (GO:0046928)3.51660670
47regulation of synaptic plasticity (GO:0048167)3.51459158
48regulation of postsynaptic membrane potential (GO:0060078)3.50412926
49long-term synaptic potentiation (GO:0060291)3.49110871
50G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.45913524
51gamma-aminobutyric acid transport (GO:0015812)3.44309837
52cell migration in hindbrain (GO:0021535)3.42078720
53positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.40430477
54regulation of dendritic spine morphogenesis (GO:0061001)3.39627840
55innervation (GO:0060384)3.39235075
56membrane hyperpolarization (GO:0060081)3.38646089
57activation of protein kinase A activity (GO:0034199)3.36972846
58neuromuscular process controlling balance (GO:0050885)3.36906046
59potassium ion homeostasis (GO:0055075)3.34557104
60cell communication by electrical coupling (GO:0010644)3.33134387
61transmission of nerve impulse (GO:0019226)3.32301845
62positive regulation of synaptic transmission, GABAergic (GO:0032230)3.32237563
63regulation of synaptic transmission, glutamatergic (GO:0051966)3.31592927
64glycine transport (GO:0015816)3.31214278
65response to pheromone (GO:0019236)3.31155794
66cerebellar Purkinje cell differentiation (GO:0021702)3.30572045
67regulation of vesicle fusion (GO:0031338)3.28235742
68regulation of neurotransmitter transport (GO:0051588)3.28233517
69auditory behavior (GO:0031223)3.26197236
70L-amino acid import (GO:0043092)3.25360981
71neuron recognition (GO:0008038)3.23693994
72neuromuscular process controlling posture (GO:0050884)3.23687584
73positive regulation of neurotransmitter secretion (GO:0001956)3.23674036
74regulation of neurotransmitter levels (GO:0001505)3.20815108
75regulation of voltage-gated calcium channel activity (GO:1901385)3.19752315
76positive regulation of neurotransmitter transport (GO:0051590)3.19496360
77negative regulation of cytosolic calcium ion concentration (GO:0051481)3.18948882
78proline transport (GO:0015824)3.18599049
79nucleobase catabolic process (GO:0046113)3.18109447
80dendrite morphogenesis (GO:0048813)3.17203648
81response to auditory stimulus (GO:0010996)3.15280535
82potassium ion import (GO:0010107)3.11338271
83mating behavior (GO:0007617)3.09922543
84negative regulation of synaptic transmission, GABAergic (GO:0032229)3.09921570
85positive regulation of dendritic spine morphogenesis (GO:0061003)3.07726207
86prepulse inhibition (GO:0060134)3.05482095
87membrane depolarization during action potential (GO:0086010)3.03426276
88dendritic spine organization (GO:0097061)3.00891224
89cerebellar granule cell differentiation (GO:0021707)3.00582001
90membrane depolarization (GO:0051899)3.00458692
91synapse assembly (GO:0007416)2.99736639
92positive regulation of synaptic transmission (GO:0050806)2.99587289
93axonal fasciculation (GO:0007413)2.97165823
94regulation of synapse maturation (GO:0090128)2.96370524
95learning (GO:0007612)2.95777822
96regulation of ARF protein signal transduction (GO:0032012)2.94981869
97regulation of synaptic transmission (GO:0050804)2.94633473
98neurofilament cytoskeleton organization (GO:0060052)2.93661444
99neuronal ion channel clustering (GO:0045161)2.93639464
100negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.93411560
101regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.93034409
102positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.92838170
103synaptic vesicle transport (GO:0048489)2.91911192
104establishment of synaptic vesicle localization (GO:0097480)2.91911192
105positive regulation of dendritic spine development (GO:0060999)2.91387134
106regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.91178826
107vesicle transport along microtubule (GO:0047496)2.91126069
108long term synaptic depression (GO:0060292)2.90655549
109postsynaptic membrane organization (GO:0001941)2.90281476
110synaptic transmission (GO:0007268)2.90224975
111cellular sodium ion homeostasis (GO:0006883)2.89040228
112negative regulation of microtubule polymerization (GO:0031115)2.87476531
113establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.87035434
114mitochondrion transport along microtubule (GO:0047497)2.87035434
115axon ensheathment in central nervous system (GO:0032291)2.84007827
116central nervous system myelination (GO:0022010)2.84007827
117neuromuscular synaptic transmission (GO:0007274)2.83990137
118amino acid import (GO:0043090)2.74088022
119positive regulation of synapse assembly (GO:0051965)2.68022803
120positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.64388962
121calcium ion-dependent exocytosis (GO:0017156)2.64075924
122cerebellar Purkinje cell layer development (GO:0021680)2.57500669
123mechanosensory behavior (GO:0007638)2.54232483
124adult walking behavior (GO:0007628)2.53236189
125social behavior (GO:0035176)2.50958272
126intraspecies interaction between organisms (GO:0051703)2.50958272
127regulation of calcium ion-dependent exocytosis (GO:0017158)2.48044761
128synapse organization (GO:0050808)2.47922826
129adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.43682226

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.30784766
2GBX2_23144817_ChIP-Seq_PC3_Human3.33221819
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.14425640
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.10750112
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.04099349
6DROSHA_22980978_ChIP-Seq_HELA_Human2.82678914
7RARB_27405468_Chip-Seq_BRAIN_Mouse2.81754082
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.77590732
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.77590732
10REST_21632747_ChIP-Seq_MESCs_Mouse2.76444416
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.73931874
12* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.61918911
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.60438178
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.55784389
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.53022243
16* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.52002508
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.44669917
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.43483072
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.41380340
20TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.38646773
21REST_18959480_ChIP-ChIP_MESCs_Mouse2.33089926
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.29068419
23EED_16625203_ChIP-ChIP_MESCs_Mouse2.28730753
24EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.12478946
25IKZF1_21737484_ChIP-ChIP_HCT116_Human2.10884216
26ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.04322121
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.01347799
28GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.97491477
29MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.96408134
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.83717909
31AR_21572438_ChIP-Seq_LNCaP_Human1.83330659
32ERG_21242973_ChIP-ChIP_JURKAT_Human1.64848576
33CTBP2_25329375_ChIP-Seq_LNCAP_Human1.58101118
34SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.54581782
35GATA1_26923725_Chip-Seq_HPCs_Mouse1.46929834
36SMAD4_21799915_ChIP-Seq_A2780_Human1.46783666
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43789990
38DNAJC2_21179169_ChIP-ChIP_NT2_Human1.40814271
39* RING1B_27294783_Chip-Seq_ESCs_Mouse1.40449043
40PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.38694725
41ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.38126369
42RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.35465238
43THAP11_20581084_ChIP-Seq_MESCs_Mouse1.33117013
44RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.32545476
45WT1_25993318_ChIP-Seq_PODOCYTE_Human1.29912983
46NR3C1_23031785_ChIP-Seq_PC12_Mouse1.27435549
47SOX2_21211035_ChIP-Seq_LN229_Gbm1.26786278
48KDM2B_26808549_Chip-Seq_K562_Human1.26581630
49AR_19668381_ChIP-Seq_PC3_Human1.25549180
50* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.24851187
51SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24620492
52P53_22127205_ChIP-Seq_FIBROBLAST_Human1.23540712
53VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.23332399
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.23112112
55TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.22629755
56SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.22534480
57IGF1R_20145208_ChIP-Seq_DFB_Human1.21733104
58TAF15_26573619_Chip-Seq_HEK293_Human1.21373970
59RING1B_27294783_Chip-Seq_NPCs_Mouse1.19529014
60RBPJ_22232070_ChIP-Seq_NCS_Mouse1.18851646
61CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.18273418
62E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.17986546
63* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.15766120
64* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.15487956
65CBX2_27304074_Chip-Seq_ESCs_Mouse1.14567149
66STAT3_23295773_ChIP-Seq_U87_Human1.14495502
67* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.13522724
68SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13138913
69ZFP57_27257070_Chip-Seq_ESCs_Mouse1.13041972
70ZNF274_21170338_ChIP-Seq_K562_Hela1.12893573
71P300_19829295_ChIP-Seq_ESCs_Human1.11302847
72OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08709862
73TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08203395
74TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07759497
75CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.07374979
76AR_25329375_ChIP-Seq_VCAP_Human1.07198718
77SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.05526856
78GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04990514
79DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.04297599
80YAP1_20516196_ChIP-Seq_MESCs_Mouse1.02961392
81SMAD_19615063_ChIP-ChIP_OVARY_Human1.02733232
82GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02408258
83ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01311564
84BMI1_23680149_ChIP-Seq_NPCS_Mouse1.00690803
85TOP2B_26459242_ChIP-Seq_MCF-7_Human0.99648071
86HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.99532246
87MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99237001
88PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.99051405
89* TCF4_23295773_ChIP-Seq_U87_Human0.98863273
90POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.98603978
91TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98603978
92PIAS1_25552417_ChIP-Seq_VCAP_Human0.97793486
93ARNT_22903824_ChIP-Seq_MCF-7_Human0.96685298
94TP53_20018659_ChIP-ChIP_R1E_Mouse0.96292311
95MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.96155318
96CTCF_27219007_Chip-Seq_Bcells_Human0.95832265
97SMAD4_21741376_ChIP-Seq_HESCs_Human0.95158608
98RNF2_27304074_Chip-Seq_NSC_Mouse0.95157703
99HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94732148
100SMAD3_21741376_ChIP-Seq_ESCs_Human0.94604904
101ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.93767172
102FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.93114638
103SOX9_26525672_Chip-Seq_HEART_Mouse0.92906398
104TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.92679522
105AHR_22903824_ChIP-Seq_MCF-7_Human0.92493625
106RUNX1_26923725_Chip-Seq_HPCs_Mouse0.92065919
107SMAD3_21741376_ChIP-Seq_HESCs_Human0.91194311
108OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.90602164
109CDX2_19796622_ChIP-Seq_MESCs_Mouse0.90079188
110SOX2_16153702_ChIP-ChIP_HESCs_Human0.88154529
111TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.86659397
112PRDM14_20953172_ChIP-Seq_ESCs_Human0.85763842
113* TET1_21490601_ChIP-Seq_MESCs_Mouse0.85638115
114RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.85460450
115REST_19997604_ChIP-ChIP_NEURONS_Mouse0.84804342
116ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.84794978
117CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.84749923
118AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.83080669
119POU5F1_16153702_ChIP-ChIP_HESCs_Human0.83072979
120NR3C1_21868756_ChIP-Seq_MCF10A_Human0.82539482
121* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.82481910
122YY1_21170310_ChIP-Seq_MESCs_Mouse0.81880806
123* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.81807448
124NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.81783028
125TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81278218
126POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.80844660
127SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80114692
128RUNX2_22187159_ChIP-Seq_PCA_Human0.79763938
129FUS_26573619_Chip-Seq_HEK293_Human0.78514505
130SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.77113283
131POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.75524380
132CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.74817421
133* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.74176343

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.47245853
2MP0003880_abnormal_central_pattern4.63937073
3MP0003635_abnormal_synaptic_transmissio4.07231062
4MP0004270_analgesia3.72610485
5MP0009745_abnormal_behavioral_response3.27658871
6MP0002063_abnormal_learning/memory/cond3.23413880
7MP0002064_seizures3.18331118
8MP0009046_muscle_twitch2.91018329
9MP0002822_catalepsy2.89586247
10MP0005423_abnormal_somatic_nervous2.79284975
11MP0001486_abnormal_startle_reflex2.70013439
12MP0002272_abnormal_nervous_system2.65982487
13MP0002572_abnormal_emotion/affect_behav2.63344683
14MP0001968_abnormal_touch/_nociception2.56513581
15MP0002734_abnormal_mechanical_nocicepti2.53661029
16MP0001501_abnormal_sleep_pattern2.09998652
17MP0008569_lethality_at_weaning1.96016642
18MP0009780_abnormal_chondrocyte_physiolo1.92425099
19MP0001984_abnormal_olfaction1.91654245
20MP0003329_amyloid_beta_deposits1.87648581
21MP0005551_abnormal_eye_electrophysiolog1.87176959
22MP0002067_abnormal_sensory_capabilities1.83824527
23MP0002736_abnormal_nociception_after1.82723893
24MP0001970_abnormal_pain_threshold1.78652033
25MP0001440_abnormal_grooming_behavior1.77081827
26MP0004811_abnormal_neuron_physiology1.75948507
27MP0002909_abnormal_adrenal_gland1.74782879
28MP0002184_abnormal_innervation1.72814053
29MP0002733_abnormal_thermal_nociception1.70590784
30MP0000778_abnormal_nervous_system1.70567021
31MP0002735_abnormal_chemical_nociception1.66460025
32MP0008877_abnormal_DNA_methylation1.65708004
33MP0004924_abnormal_behavior1.64967031
34MP0005386_behavior/neurological_phenoty1.64967031
35MP0002557_abnormal_social/conspecific_i1.63330258
36MP0003879_abnormal_hair_cell1.62363527
37MP0004858_abnormal_nervous_system1.61571448
38MP0000955_abnormal_spinal_cord1.61187990
39MP0004885_abnormal_endolymph1.60615163
40MP0003123_paternal_imprinting1.60136994
41MP0001502_abnormal_circadian_rhythm1.59554375
42MP0003121_genomic_imprinting1.56790453
43MP0001529_abnormal_vocalization1.53957071
44MP0002882_abnormal_neuron_morphology1.53713814
45MP0005646_abnormal_pituitary_gland1.49200859
46MP0002090_abnormal_vision1.47843020
47MP0006292_abnormal_olfactory_placode1.44777664
48MP0003633_abnormal_nervous_system1.41363254
49MP0002066_abnormal_motor_capabilities/c1.41082773
50MP0003787_abnormal_imprinting1.31907717
51MP0003122_maternal_imprinting1.30022543
52MP0000013_abnormal_adipose_tissue1.28559157
53MP0000566_synostosis1.28436221
54MP0005645_abnormal_hypothalamus_physiol1.26879617
55MP0002229_neurodegeneration1.22645214
56MP0001905_abnormal_dopamine_level1.19391039
57MP0003631_nervous_system_phenotype1.18947628
58MP0000920_abnormal_myelination1.17939828
59MP0004142_abnormal_muscle_tone1.17607977
60MP0002102_abnormal_ear_morphology1.17559427
61MP0006072_abnormal_retinal_apoptosis1.13036367
62MP0002152_abnormal_brain_morphology1.12958376
63MP0003119_abnormal_digestive_system1.12603411
64MP0004233_abnormal_muscle_weight1.12182575
65MP0003634_abnormal_glial_cell1.10378626
66MP0005394_taste/olfaction_phenotype1.10155124
67MP0005499_abnormal_olfactory_system1.10155124
68MP0006276_abnormal_autonomic_nervous1.08139090
69MP0000049_abnormal_middle_ear1.00497296
70MP0003938_abnormal_ear_development0.99745047
71MP0004133_heterotaxia0.98833206
72MP0010386_abnormal_urinary_bladder0.97874789
73MP0004742_abnormal_vestibular_system0.97840576
74MP0004145_abnormal_muscle_electrophysio0.97188355
75MP0003075_altered_response_to0.96868924
76MP0004043_abnormal_pH_regulation0.96860363
77MP0003690_abnormal_glial_cell0.96697500
78MP0000751_myopathy0.96673628
79MP0002069_abnormal_eating/drinking_beha0.95362035
80MP0008872_abnormal_physiological_respon0.94882411
81MP0003283_abnormal_digestive_organ0.92918972
82MP0001177_atelectasis0.92335691
83MP0002752_abnormal_somatic_nervous0.92183686
84MP0004085_abnormal_heartbeat0.91328705
85MP0003698_abnormal_male_reproductive0.90784847
86MP0000631_abnormal_neuroendocrine_gland0.87996497
87MP0005253_abnormal_eye_physiology0.87689260
88MP0008961_abnormal_basal_metabolism0.87514009
89MP0001346_abnormal_lacrimal_gland0.86966893
90MP0008789_abnormal_olfactory_epithelium0.86149445
91MP0002249_abnormal_larynx_morphology0.85351602
92MP0005623_abnormal_meninges_morphology0.85127795
93MP0005410_abnormal_fertilization0.84889520
94MP0004215_abnormal_myocardial_fiber0.84518492
95MP0000537_abnormal_urethra_morphology0.83858196
96MP0003632_abnormal_nervous_system0.83856176
97MP0003890_abnormal_embryonic-extraembry0.83292069
98MP0001963_abnormal_hearing_physiology0.82058949
99MP0000026_abnormal_inner_ear0.81270627
100MP0002751_abnormal_autonomic_nervous0.80923509
101MP0002653_abnormal_ependyma_morphology0.80584914
102MP0001485_abnormal_pinna_reflex0.79700036
103MP0005187_abnormal_penis_morphology0.79565821
104MP0008874_decreased_physiological_sensi0.78162951
105MP0001188_hyperpigmentation0.77122876
106MP0002638_abnormal_pupillary_reflex0.75021283
107MP0003137_abnormal_impulse_conducting0.74466697
108MP0003136_yellow_coat_color0.73731795
109MP0001293_anophthalmia0.73042746
110MP0000604_amyloidosis0.72606351
111MP0002161_abnormal_fertility/fecundity0.71160433
112MP0005535_abnormal_body_temperature0.70791623
113MP0002081_perinatal_lethality0.70447125
114MP0009672_abnormal_birth_weight0.69693535
115MP0001929_abnormal_gametogenesis0.68898509
116MP0002210_abnormal_sex_determination0.67713011
117MP0000569_abnormal_digit_pigmentation0.67551494
118MP0003937_abnormal_limbs/digits/tail_de0.66433548
119MP0010770_preweaning_lethality0.64697649
120MP0005195_abnormal_posterior_eye0.64507830
121MP0003172_abnormal_lysosome_physiology0.64206159
122MP0001664_abnormal_digestion0.64158737
123MP0002234_abnormal_pharynx_morphology0.59905704
124MP0002837_dystrophic_cardiac_calcinosis0.58551660
125MP0000003_abnormal_adipose_tissue0.58247885
126MP0003861_abnormal_nervous_system0.57581069
127MP0001299_abnormal_eye_distance/0.57343943
128MP0001943_abnormal_respiration0.56750671
129MP0005167_abnormal_blood-brain_barrier0.55227897

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.70911184
2Focal motor seizures (HP:0011153)6.57529552
3Focal seizures (HP:0007359)5.14957230
4Visual hallucinations (HP:0002367)4.98993389
5Epileptic encephalopathy (HP:0200134)4.88930933
6Progressive cerebellar ataxia (HP:0002073)4.07129151
7Atonic seizures (HP:0010819)3.99909883
8Absence seizures (HP:0002121)3.92085550
9Febrile seizures (HP:0002373)3.84420024
10Ankle clonus (HP:0011448)3.80934395
11Action tremor (HP:0002345)3.77456853
12Supranuclear gaze palsy (HP:0000605)3.72235533
13Dialeptic seizures (HP:0011146)3.61469345
14Generalized tonic-clonic seizures (HP:0002069)3.56622715
15Depression (HP:0000716)3.55068924
16Congenital stationary night blindness (HP:0007642)3.41401021
17Dysdiadochokinesis (HP:0002075)3.23821848
18Postural instability (HP:0002172)3.19356331
19Dysmetria (HP:0001310)3.17244622
20Anxiety (HP:0000739)3.14701451
21Broad-based gait (HP:0002136)3.08263708
22Gaze-evoked nystagmus (HP:0000640)3.07557389
23Central scotoma (HP:0000603)3.04358982
24Impaired vibration sensation in the lower limbs (HP:0002166)2.98050588
25Urinary bladder sphincter dysfunction (HP:0002839)2.96494804
26Truncal ataxia (HP:0002078)2.96118851
27Poor eye contact (HP:0000817)2.95323425
28Mutism (HP:0002300)2.94327052
29Neurofibrillary tangles (HP:0002185)2.93172556
30Hemiparesis (HP:0001269)2.80612550
31Spastic gait (HP:0002064)2.78721126
32Polyphagia (HP:0002591)2.78276597
33Torticollis (HP:0000473)2.75500224
34Cerebral hypomyelination (HP:0006808)2.73936598
35Cerebral inclusion bodies (HP:0100314)2.71341838
36Impaired social interactions (HP:0000735)2.69273325
37Abnormal social behavior (HP:0012433)2.69273325
38Abnormal eating behavior (HP:0100738)2.68046235
39Intention tremor (HP:0002080)2.66366677
40Genetic anticipation (HP:0003743)2.64718090
41Abnormality of the labia minora (HP:0012880)2.62762502
42Cortical dysplasia (HP:0002539)2.60665993
43Papilledema (HP:0001085)2.59076802
44Urinary urgency (HP:0000012)2.56771509
45Scanning speech (HP:0002168)2.53083364
46Epileptiform EEG discharges (HP:0011182)2.52469894
47Focal dystonia (HP:0004373)2.49718604
48Abnormality of the lower motor neuron (HP:0002366)2.49623334
49Hyperventilation (HP:0002883)2.49560444
50Abnormality of macular pigmentation (HP:0008002)2.49350889
51Impaired smooth pursuit (HP:0007772)2.48689617
52Hemiplegia (HP:0002301)2.48101845
53Amblyopia (HP:0000646)2.47866113
54Bradykinesia (HP:0002067)2.46529060
55EEG with generalized epileptiform discharges (HP:0011198)2.46512243
56Megalencephaly (HP:0001355)2.46028967
57Pheochromocytoma (HP:0002666)2.46027715
58Ventricular fibrillation (HP:0001663)2.45295454
59Insomnia (HP:0100785)2.41493789
60Drooling (HP:0002307)2.39723757
61Excessive salivation (HP:0003781)2.39723757
62Sleep apnea (HP:0010535)2.33489051
63Poor suck (HP:0002033)2.28995971
64Retinal dysplasia (HP:0007973)2.27737015
65Abnormality of binocular vision (HP:0011514)2.27365568
66Diplopia (HP:0000651)2.27365568
67Hypsarrhythmia (HP:0002521)2.27346571
68Lower limb muscle weakness (HP:0007340)2.23062995
69Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.23035215
70Craniofacial dystonia (HP:0012179)2.22412910
71Dysmetric saccades (HP:0000641)2.21267579
72Abnormality of ocular smooth pursuit (HP:0000617)2.21228661
73Insidious onset (HP:0003587)2.16989964
74Termporal pattern (HP:0011008)2.16989964
75Stereotypic behavior (HP:0000733)2.14901405
76Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.13997042
77Abnormality of the corticospinal tract (HP:0002492)2.12405577
78Failure to thrive in infancy (HP:0001531)2.10927753
79Progressive inability to walk (HP:0002505)2.07732231
80Neuroendocrine neoplasm (HP:0100634)2.07629423
81Absent speech (HP:0001344)2.07472101
82Clonus (HP:0002169)2.07452885
83Spastic tetraplegia (HP:0002510)2.06963993
84Impaired vibratory sensation (HP:0002495)2.04689609
85Pointed chin (HP:0000307)2.04232105
86Annular pancreas (HP:0001734)2.03369530
87Neoplasm of the heart (HP:0100544)2.01653581
88Generalized myoclonic seizures (HP:0002123)2.01608062
89Incomplete penetrance (HP:0003829)2.01204750
90Limb dystonia (HP:0002451)2.01023021
91Scotoma (HP:0000575)1.98903288
92Agitation (HP:0000713)1.97333830
93CNS hypomyelination (HP:0003429)1.97326318
94Double outlet right ventricle (HP:0001719)1.96131541
95Congenital malformation of the right heart (HP:0011723)1.96131541
96Hypoplasia of the brainstem (HP:0002365)1.94312405
97Aplasia/Hypoplasia of the brainstem (HP:0007362)1.94312405
98Gait imbalance (HP:0002141)1.93751045
99Status epilepticus (HP:0002133)1.89042423
100Rigidity (HP:0002063)1.88771047
101Fetal akinesia sequence (HP:0001989)1.88283739
102Hand muscle atrophy (HP:0009130)1.87167219
103Abnormal EKG (HP:0003115)1.86972990
104Delusions (HP:0000746)1.86570942
105Prolonged QT interval (HP:0001657)1.85651507
106Spastic tetraparesis (HP:0001285)1.84698887
107Blue irides (HP:0000635)1.84468000
108Muscular hypotonia of the trunk (HP:0008936)1.83587831
109Morphological abnormality of the pyramidal tract (HP:0002062)1.83085840
110Gait ataxia (HP:0002066)1.82995580
111Amyotrophic lateral sclerosis (HP:0007354)1.82945820
112Akinesia (HP:0002304)1.81607227
113Optic nerve hypoplasia (HP:0000609)1.80904238
114Abnormality of saccadic eye movements (HP:0000570)1.80411054
115Neuronal loss in central nervous system (HP:0002529)1.77775500
116Lissencephaly (HP:0001339)1.76857130
117Peripheral hypomyelination (HP:0007182)1.74768119
118Specific learning disability (HP:0001328)1.74209142
119Split foot (HP:0001839)1.74124733
120Hypoventilation (HP:0002791)1.73912415
121Resting tremor (HP:0002322)1.73870626
122Turricephaly (HP:0000262)1.73299641
123Thickened helices (HP:0000391)1.72843102
124Abnormal gallbladder physiology (HP:0012438)1.72808298
125Cholecystitis (HP:0001082)1.72808298
126Degeneration of the lateral corticospinal tracts (HP:0002314)1.70367460
127Hepatoblastoma (HP:0002884)1.67637686
128Esotropia (HP:0000565)1.64612404
129Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.63812189
130Tetraplegia (HP:0002445)1.62912805
131Morphological abnormality of the inner ear (HP:0011390)1.57149070
132Hypoplasia of the corpus callosum (HP:0002079)1.56767771
133Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.52043959
134Type II lissencephaly (HP:0007260)1.51706153
135Septo-optic dysplasia (HP:0100842)1.51225544
136Atrophy/Degeneration involving motor neurons (HP:0007373)1.49619850
137Choreoathetosis (HP:0001266)1.49190648
138Apathy (HP:0000741)1.48224295
139Congenital primary aphakia (HP:0007707)1.42714691

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.24803727
2NTRK34.03316390
3MAP3K93.72564094
4PAK62.78965892
5DAPK22.75184905
6MARK12.64229521
7MAP3K42.63499506
8MINK12.60516354
9PRKD32.42598314
10KSR22.16624272
11PRPF4B2.01227066
12MAP2K71.99623437
13NTRK11.92653291
14CAMKK11.92090663
15NTRK21.90523820
16DYRK21.85038043
17CDK191.75351939
18CDK51.65082931
19CASK1.52486267
20KSR11.51117075
21UHMK11.49947091
22MAP2K41.44064858
23DAPK11.41258617
24MAP3K131.38809620
25STK381.38230085
26TNIK1.37283425
27ARAF1.36002391
28TRIM281.26812387
29OXSR11.23090382
30PLK21.22343248
31CSNK1G31.21863933
32TESK11.20744721
33GRK51.20276596
34SGK4941.18455525
35SGK2231.18455525
36PRKCG1.14522118
37MAP3K121.11820070
38MAP3K21.11496661
39TYRO31.10409643
40CDK151.09145672
41CDK181.08894231
42CSNK1A1L1.08236644
43FES1.08131815
44CDK141.08066534
45PHKG21.07836254
46PHKG11.07836254
47CAMK11.07680855
48SIK21.05691227
49RIPK41.03379216
50TAOK11.03360416
51CAMK2A0.99605440
52MAPK130.99288549
53FGFR20.98838461
54CSNK1G10.98448337
55PRKCH0.96750015
56PAK30.96320503
57CAMK2B0.95770418
58CDK11A0.95761374
59PNCK0.94825735
60CAMKK20.93386948
61MAP4K20.92573213
62TSSK60.87161075
63PINK10.86628271
64DYRK1A0.85368480
65PTK2B0.84664342
66STK110.84199066
67NEK10.83324358
68MARK20.82634348
69BRAF0.81838507
70RET0.80941106
71BUB10.77849222
72ALK0.77344968
73STK390.76174490
74LIMK10.75726770
75CAMK2D0.72367551
76PLK40.70340976
77WNK30.69925608
78RAF10.69716178
79SGK10.69214848
80NEK60.67481342
81LMTK20.67424246
82MAP3K70.67111726
83RIPK10.66966303
84MAP3K10.66597026
85SRPK10.65610415
86PDK10.64651531
87AURKA0.64343276
88SGK30.64014917
89PDPK10.63504770
90CDC70.62646743
91WNK10.62332301
92SGK20.61796641
93PLK30.61413171
94CDC42BPA0.61319118
95CAMK1G0.60679595
96CAMK1D0.60125797
97PKN10.59932996
98TNK20.59745735
99DAPK30.58977171
100ROCK20.57817735
101CSNK1G20.56247598
102STK38L0.55891359
103WNK40.54580487
104BRSK10.54485754
105CSNK1E0.54137407
106RPS6KA30.54092267
107DYRK30.53077090
108LATS20.52550907
109CAMK2G0.52290678
110ICK0.51426894
111CAMK40.51283785
112DMPK0.49286700
113MAPK100.48642877
114PRKCZ0.48346678
115PRKCE0.48298200
116FYN0.47979562
117PLK10.47050254
118FER0.47008973
119BCR0.43547799
120CSNK1D0.43052041
121BRD40.42804277
122GSK3B0.41331403
123MAPKAPK50.40488316
124BMPR20.40032093
125DYRK1B0.39526118
126STK160.39435994
127CDK10.39399458
128PRKDC0.39121799
129MAP2K10.39083455
130TTK0.38883894
131CDK20.38008534

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.53520368
2Nicotine addiction_Homo sapiens_hsa050333.48911109
3GABAergic synapse_Homo sapiens_hsa047272.89312629
4Olfactory transduction_Homo sapiens_hsa047402.86685229
5Circadian entrainment_Homo sapiens_hsa047132.75531006
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.66557376
7Morphine addiction_Homo sapiens_hsa050322.61526196
8Glutamatergic synapse_Homo sapiens_hsa047242.50475776
9Long-term potentiation_Homo sapiens_hsa047202.32920179
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.29403373
11Amphetamine addiction_Homo sapiens_hsa050312.24611590
12Insulin secretion_Homo sapiens_hsa049112.21065558
13Salivary secretion_Homo sapiens_hsa049702.19447330
14Dopaminergic synapse_Homo sapiens_hsa047282.08254108
15Cholinergic synapse_Homo sapiens_hsa047251.97443597
16Gastric acid secretion_Homo sapiens_hsa049711.87397190
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.85284560
18Renin secretion_Homo sapiens_hsa049241.74051373
19Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.73808771
20Vitamin B6 metabolism_Homo sapiens_hsa007501.73059845
21Oxytocin signaling pathway_Homo sapiens_hsa049211.70174943
22Serotonergic synapse_Homo sapiens_hsa047261.60932510
23Cocaine addiction_Homo sapiens_hsa050301.60579649
24Long-term depression_Homo sapiens_hsa047301.56811269
25Taste transduction_Homo sapiens_hsa047421.49899233
26Collecting duct acid secretion_Homo sapiens_hsa049661.49749952
27Calcium signaling pathway_Homo sapiens_hsa040201.49114712
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.46239590
29Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.41223729
30GnRH signaling pathway_Homo sapiens_hsa049121.36821143
31Gap junction_Homo sapiens_hsa045401.34833452
32Nitrogen metabolism_Homo sapiens_hsa009101.29445063
33Type II diabetes mellitus_Homo sapiens_hsa049301.25704648
34cAMP signaling pathway_Homo sapiens_hsa040241.24488426
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.21424346
36Phototransduction_Homo sapiens_hsa047441.16993550
37Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.16014583
38Axon guidance_Homo sapiens_hsa043601.11963820
39Oxidative phosphorylation_Homo sapiens_hsa001901.09897924
402-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.09301950
41cGMP-PKG signaling pathway_Homo sapiens_hsa040221.09117099
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.07499667
43Phosphatidylinositol signaling system_Homo sapiens_hsa040701.07487662
44Parkinsons disease_Homo sapiens_hsa050121.06509961
45Cardiac muscle contraction_Homo sapiens_hsa042601.05937189
46Glioma_Homo sapiens_hsa052141.05303228
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.04292819
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.03043161
49Vascular smooth muscle contraction_Homo sapiens_hsa042701.03035882
50Estrogen signaling pathway_Homo sapiens_hsa049151.02907901
51Vibrio cholerae infection_Homo sapiens_hsa051101.00179058
52Melanogenesis_Homo sapiens_hsa049160.95787876
53ErbB signaling pathway_Homo sapiens_hsa040120.94926094
54Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.92818903
55Dilated cardiomyopathy_Homo sapiens_hsa054140.91900411
56Arginine and proline metabolism_Homo sapiens_hsa003300.89673891
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88670041
58Pancreatic secretion_Homo sapiens_hsa049720.88477558
59Phospholipase D signaling pathway_Homo sapiens_hsa040720.88452552
60Biosynthesis of amino acids_Homo sapiens_hsa012300.88379271
61Alzheimers disease_Homo sapiens_hsa050100.87889057
62Huntingtons disease_Homo sapiens_hsa050160.86049498
63Hippo signaling pathway_Homo sapiens_hsa043900.85471251
64Thyroid hormone synthesis_Homo sapiens_hsa049180.79355155
65Hedgehog signaling pathway_Homo sapiens_hsa043400.79203728
66mRNA surveillance pathway_Homo sapiens_hsa030150.79047285
67Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.78742894
68Oocyte meiosis_Homo sapiens_hsa041140.78349207
69Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.78250344
70Dorso-ventral axis formation_Homo sapiens_hsa043200.76407680
71Circadian rhythm_Homo sapiens_hsa047100.75491953
72MAPK signaling pathway_Homo sapiens_hsa040100.70925117
73Folate biosynthesis_Homo sapiens_hsa007900.70664230
74Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.66076745
75Choline metabolism in cancer_Homo sapiens_hsa052310.65470913
76Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65260273
77Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.64820140
78Alcoholism_Homo sapiens_hsa050340.64388360
79Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63584549
80Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.62956113
81Endocytosis_Homo sapiens_hsa041440.62286857
82Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.60276937
83Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.59869425
84Steroid biosynthesis_Homo sapiens_hsa001000.58190956
85Basal cell carcinoma_Homo sapiens_hsa052170.57834888
86Ras signaling pathway_Homo sapiens_hsa040140.57832063
87Sulfur relay system_Homo sapiens_hsa041220.57150132
88Thyroid hormone signaling pathway_Homo sapiens_hsa049190.55378871
89Renal cell carcinoma_Homo sapiens_hsa052110.55107791
90VEGF signaling pathway_Homo sapiens_hsa043700.54765095
91mTOR signaling pathway_Homo sapiens_hsa041500.54385047
92Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.54138108
93Glucagon signaling pathway_Homo sapiens_hsa049220.53917431
94beta-Alanine metabolism_Homo sapiens_hsa004100.53259637
95Inositol phosphate metabolism_Homo sapiens_hsa005620.52757418
96Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.51839564
97Butanoate metabolism_Homo sapiens_hsa006500.51287891
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.51141876
99Rap1 signaling pathway_Homo sapiens_hsa040150.50903317
100AMPK signaling pathway_Homo sapiens_hsa041520.49946074
101Neurotrophin signaling pathway_Homo sapiens_hsa047220.49678973
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49547073
103RNA transport_Homo sapiens_hsa030130.49030676
104Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.48393387
105Carbon metabolism_Homo sapiens_hsa012000.48201969
106SNARE interactions in vesicular transport_Homo sapiens_hsa041300.47905486
107Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.47698743
108Type I diabetes mellitus_Homo sapiens_hsa049400.47491771
109RNA polymerase_Homo sapiens_hsa030200.46908734
110Arginine biosynthesis_Homo sapiens_hsa002200.46263535
111Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.45856592
112Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45115612
113Bile secretion_Homo sapiens_hsa049760.44968860
114Cysteine and methionine metabolism_Homo sapiens_hsa002700.44965809
115Base excision repair_Homo sapiens_hsa034100.44313740
116Fatty acid biosynthesis_Homo sapiens_hsa000610.43991689
117Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41270764
118Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40608356
119Basal transcription factors_Homo sapiens_hsa030220.39882261
120Mismatch repair_Homo sapiens_hsa034300.39790044
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39684376
122Prion diseases_Homo sapiens_hsa050200.39464454
123Wnt signaling pathway_Homo sapiens_hsa043100.39086307
124Fatty acid elongation_Homo sapiens_hsa000620.38006801
125Non-small cell lung cancer_Homo sapiens_hsa052230.37404477
126Ovarian steroidogenesis_Homo sapiens_hsa049130.35994025
127Endometrial cancer_Homo sapiens_hsa052130.34030217
128Insulin signaling pathway_Homo sapiens_hsa049100.32589666
129Chemokine signaling pathway_Homo sapiens_hsa040620.32530365
130Central carbon metabolism in cancer_Homo sapiens_hsa052300.32311132
131Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.32177444
132Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31832930
133Tight junction_Homo sapiens_hsa045300.27945429
134African trypanosomiasis_Homo sapiens_hsa051430.27375101
135Glycerophospholipid metabolism_Homo sapiens_hsa005640.25301185
136Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.24855519
137Mineral absorption_Homo sapiens_hsa049780.24299139

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