MRGBP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.71080230
2DNA unwinding involved in DNA replication (GO:0006268)4.91884893
3viral transcription (GO:0019083)4.90343879
4heterochromatin organization (GO:0070828)4.65925566
5translational termination (GO:0006415)4.65733223
6mitotic sister chromatid segregation (GO:0000070)4.37339138
7DNA strand elongation involved in DNA replication (GO:0006271)4.32172631
8translational elongation (GO:0006414)4.23705933
9DNA strand elongation (GO:0022616)4.19191541
10ribosomal small subunit biogenesis (GO:0042274)4.05861639
11nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.01260023
12telomere maintenance via semi-conservative replication (GO:0032201)3.99660526
13SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.95899124
14regulation of translational fidelity (GO:0006450)3.94193554
15protein targeting to ER (GO:0045047)3.82372083
16cotranslational protein targeting to membrane (GO:0006613)3.82302945
17protein localization to kinetochore (GO:0034501)3.80694248
18antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.78907525
19antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.78907525
20maturation of SSU-rRNA (GO:0030490)3.73650708
21DNA deamination (GO:0045006)3.67721598
22viral life cycle (GO:0019058)3.65529343
23protein localization to chromosome, centromeric region (GO:0071459)3.63727498
24establishment of protein localization to endoplasmic reticulum (GO:0072599)3.63119953
25translational initiation (GO:0006413)3.61183899
26DNA replication initiation (GO:0006270)3.61087281
27protein localization to endoplasmic reticulum (GO:0070972)3.56988838
28cellular protein complex disassembly (GO:0043624)3.56978848
29translesion synthesis (GO:0019985)3.52633648
30telomere maintenance via recombination (GO:0000722)3.48964701
31mitotic recombination (GO:0006312)3.47585337
32proline biosynthetic process (GO:0006561)3.47377295
33chromosome condensation (GO:0030261)3.45276163
34protein complex disassembly (GO:0043241)3.42923944
35negative regulation of DNA-templated transcription, elongation (GO:0032785)3.40181776
36regulation of translational termination (GO:0006449)3.38285369
37negative regulation of RNA splicing (GO:0033119)3.35552801
38positive regulation of B cell differentiation (GO:0045579)3.34563808
39regulation of mitochondrial translation (GO:0070129)3.33030674
40nucleobase-containing small molecule interconversion (GO:0015949)3.31088613
41regulation of mammary gland epithelial cell proliferation (GO:0033599)3.30981493
42mitotic metaphase plate congression (GO:0007080)3.28450163
43CENP-A containing nucleosome assembly (GO:0034080)3.28162558
44chromatin remodeling at centromere (GO:0031055)3.27481234
45regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.27220687
46negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.27178553
47antigen processing and presentation of endogenous antigen (GO:0019883)3.19983221
48macromolecular complex disassembly (GO:0032984)3.19338536
49nuclear-transcribed mRNA catabolic process (GO:0000956)3.18388593
50regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.18295309
51formation of translation preinitiation complex (GO:0001731)3.16951001
52ribosome biogenesis (GO:0042254)3.16872358
53antigen processing and presentation via MHC class Ib (GO:0002475)3.15910828
54DNA replication-independent nucleosome assembly (GO:0006336)3.12714994
55DNA replication-independent nucleosome organization (GO:0034724)3.12714994
56regulation of histone H3-K9 methylation (GO:0051570)3.09313589
57telomere maintenance via telomere lengthening (GO:0010833)3.07639810
58ribosomal large subunit biogenesis (GO:0042273)3.06409513
59mRNA catabolic process (GO:0006402)3.04112523
60spliceosomal tri-snRNP complex assembly (GO:0000244)3.03026791
61nucleotide-excision repair, DNA gap filling (GO:0006297)3.01994523
62DNA packaging (GO:0006323)3.00687445
63negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.00464689
64RNA catabolic process (GO:0006401)3.00429832
65regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.98600249
66positive regulation of gamma-delta T cell activation (GO:0046645)2.95883710
67nuclear pore complex assembly (GO:0051292)2.95745608
68histone exchange (GO:0043486)2.94495779
69regulation of nuclear cell cycle DNA replication (GO:0033262)2.91357339
70attachment of spindle microtubules to kinetochore (GO:0008608)2.90560161
71DNA duplex unwinding (GO:0032508)2.90416178
72mitotic nuclear envelope disassembly (GO:0007077)2.90063709
73regulation of protein heterodimerization activity (GO:0043497)2.88681037
74folic acid metabolic process (GO:0046655)2.86995230
75DNA geometric change (GO:0032392)2.84712559
76antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.83669676
77deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.83304160
78nucleosome disassembly (GO:0006337)2.80645700
79protein-DNA complex disassembly (GO:0032986)2.80645700
80DNA topological change (GO:0006265)2.80337414
81COPI coating of Golgi vesicle (GO:0048205)2.80217387
82Golgi transport vesicle coating (GO:0048200)2.80217387
83positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.78047257
84viral mRNA export from host cell nucleus (GO:0046784)2.77587794
85mitotic sister chromatid cohesion (GO:0007064)2.77122451
86postreplication repair (GO:0006301)2.77013028
87establishment of viral latency (GO:0019043)2.76601722
88establishment of apical/basal cell polarity (GO:0035089)2.76127413
89histone H2A acetylation (GO:0043968)2.76056346
90termination of RNA polymerase II transcription (GO:0006369)2.72483697
91positive regulation of DNA-dependent DNA replication (GO:2000105)2.71833892
92chromatin assembly or disassembly (GO:0006333)2.71809353
93ribonucleoprotein complex biogenesis (GO:0022613)2.71756263
94ATP-dependent chromatin remodeling (GO:0043044)2.71205165
95negative regulation of histone methylation (GO:0031061)2.70540324
96protein maturation by protein folding (GO:0022417)2.70094583
97maternal placenta development (GO:0001893)2.69687867
98nuclear pore organization (GO:0006999)2.69350758
99chromatin assembly (GO:0031497)2.68937421
100protein complex localization (GO:0031503)2.66718401
101negative regulation of viral release from host cell (GO:1902187)2.66671840
102negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.65877156
103negative regulation of mRNA processing (GO:0050686)2.65519889
104nuclear envelope disassembly (GO:0051081)2.65281690
105membrane disassembly (GO:0030397)2.65281690
106mitotic chromosome condensation (GO:0007076)2.65029214
107immunoglobulin mediated immune response (GO:0016064)2.64486345
108kinetochore organization (GO:0051383)2.63922615
109negative regulation of mRNA metabolic process (GO:1903312)2.62442241
110telomere maintenance (GO:0000723)2.62110921
111establishment of integrated proviral latency (GO:0075713)2.62004050
112pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.61975865
113sister chromatid segregation (GO:0000819)2.61661020
114DNA replication-dependent nucleosome organization (GO:0034723)2.61361518
115DNA replication-dependent nucleosome assembly (GO:0006335)2.61361518
116regulation of B cell differentiation (GO:0045577)2.60132474
117telomere organization (GO:0032200)2.58521403
118rRNA processing (GO:0006364)2.57061661
119protein localization to chromosome (GO:0034502)2.56897860
120DNA conformation change (GO:0071103)2.56209982
121modulation by virus of host process (GO:0019054)2.54762593
122mammary gland epithelial cell proliferation (GO:0033598)2.54721681
123DNA replication checkpoint (GO:0000076)2.54532049
124nucleobase biosynthetic process (GO:0046112)2.54053402
125peptidyl-arginine omega-N-methylation (GO:0035247)2.52584276
126cellular protein complex localization (GO:0034629)2.52235900
127ncRNA 3-end processing (GO:0043628)2.51898880
128positive regulation of viral transcription (GO:0050434)2.51878193
129histone H2B ubiquitination (GO:0033523)2.50982801
130positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.50872213
131tRNA methylation (GO:0030488)2.50645904
132ear development (GO:0043583)2.50363000
133protein targeting to membrane (GO:0006612)2.50221599
134positive regulation of histone H3-K4 methylation (GO:0051571)2.49567695
135RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.49076690
136mRNA splicing, via spliceosome (GO:0000398)2.49076690
137NIK/NF-kappaB signaling (GO:0038061)2.48765137
138translation (GO:0006412)2.48757837
1393-UTR-mediated mRNA stabilization (GO:0070935)2.47210889
140GDP-mannose metabolic process (GO:0019673)2.46926734
141chromosome segregation (GO:0007059)2.46896679
142negative regulation of necroptotic process (GO:0060546)2.46511606
143mitotic nuclear envelope reassembly (GO:0007084)2.46406755
144nuclear envelope reassembly (GO:0031468)2.46406755
145modulation by symbiont of host cellular process (GO:0044068)2.46404320
146histone mRNA metabolic process (GO:0008334)2.46101029
147activation of Rac GTPase activity (GO:0032863)2.45479435
148folic acid-containing compound biosynthetic process (GO:0009396)2.45186639
149branching involved in mammary gland duct morphogenesis (GO:0060444)2.45059205
150cellular component biogenesis (GO:0044085)2.43180320
151DNA synthesis involved in DNA repair (GO:0000731)2.41123159
152trophoblast giant cell differentiation (GO:0060707)2.39487471

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.10544757
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.39940715
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.31339388
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.30449264
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.00682029
6MYC_22102868_ChIP-Seq_BL_Human2.99544449
7SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.88192714
8TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.86884057
9ZNF263_19887448_ChIP-Seq_K562_Human2.64197632
10FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.63258699
11SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.49181282
12TP63_17297297_ChIP-ChIP_HaCaT_Human2.43707713
13CIITA_25753668_ChIP-Seq_RAJI_Human2.23777656
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.22801840
15VDR_21846776_ChIP-Seq_THP-1_Human2.22371997
16TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.21182869
17MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.18969153
18MYC_19079543_ChIP-ChIP_MESCs_Mouse2.18801611
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.10217589
20ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.09318068
21MYC_19030024_ChIP-ChIP_MESCs_Mouse2.08932871
22EST1_17652178_ChIP-ChIP_JURKAT_Human2.03149884
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.02037012
24IRF8_22096565_ChIP-ChIP_GC-B_Human2.01761737
25GABP_17652178_ChIP-ChIP_JURKAT_Human2.01366777
26XRN2_22483619_ChIP-Seq_HELA_Human2.00008665
27SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.97001055
28ELF1_17652178_ChIP-ChIP_JURKAT_Human1.95583765
29SCL_19346495_ChIP-Seq_HPC-7_Human1.92997185
30VDR_23849224_ChIP-Seq_CD4+_Human1.92434509
31MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.88190301
32IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.87973223
33FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.86174489
34FOXP3_21729870_ChIP-Seq_TREG_Human1.83074790
35ETS1_20019798_ChIP-Seq_JURKAT_Human1.80753595
36JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.78525275
37E2F1_21310950_ChIP-Seq_MCF-7_Human1.76587961
38KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.75240426
39NELFA_20434984_ChIP-Seq_ESCs_Mouse1.74187502
40NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.72485075
41ELK3_25401928_ChIP-Seq_HUVEC_Human1.72194917
42ERG_20887958_ChIP-Seq_HPC-7_Mouse1.71576309
43RACK7_27058665_Chip-Seq_MCF-7_Human1.69450485
44SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.69083428
45RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.65509598
46LXR_22292898_ChIP-Seq_THP-1_Human1.63660054
47SPI1_23547873_ChIP-Seq_NB4_Human1.63569272
48UTX_26944678_Chip-Seq_JUKART_Human1.62464923
49CREB1_15753290_ChIP-ChIP_HEK293T_Human1.61866139
50MYB_26560356_Chip-Seq_TH2_Human1.59550114
51ESR1_15608294_ChIP-ChIP_MCF-7_Human1.58482766
52FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.58121636
53RARG_19884340_ChIP-ChIP_MEFs_Mouse1.58109277
54DCP1A_22483619_ChIP-Seq_HELA_Human1.55066598
55PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.53914845
56TCF7_22412390_ChIP-Seq_EML_Mouse1.53839277
57MAF_26560356_Chip-Seq_TH1_Human1.53829194
58GABP_19822575_ChIP-Seq_HepG2_Human1.52918768
59TTF2_22483619_ChIP-Seq_HELA_Human1.52711481
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.51889380
61TP63_19390658_ChIP-ChIP_HaCaT_Human1.51843601
62HOXB4_20404135_ChIP-ChIP_EML_Mouse1.51633568
63ZFX_18555785_ChIP-Seq_MESCs_Mouse1.48073979
64MYB_21317192_ChIP-Seq_ERMYB_Mouse1.47578558
65TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.47265675
66MYB_26560356_Chip-Seq_TH1_Human1.43881122
67NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.43717864
68CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.41466370
69PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40439073
70FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.40308135
71KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.40187681
72MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.38825490
73KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.37814742
74TET1_21451524_ChIP-Seq_MESCs_Mouse1.37380477
75STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.37012037
76MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.36166748
77ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.34347710
78GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.32983399
79MYCN_18555785_ChIP-Seq_MESCs_Mouse1.32978032
80CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.32643534
81E2F1_18555785_ChIP-Seq_MESCs_Mouse1.31627189
82STAT3_1855785_ChIP-Seq_MESCs_Mouse1.30158183
83ATF3_27146783_Chip-Seq_COLON_Human1.29906184
84KDM5A_27292631_Chip-Seq_BREAST_Human1.27854170
85POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.27371888
86SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.26911619
87RUNX1_22412390_ChIP-Seq_EML_Mouse1.24777548
88VDR_24763502_ChIP-Seq_THP-1_Human1.24139058
89CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.22615807
90STAT4_19710469_ChIP-ChIP_TH1__Mouse1.21897610
91TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.21214621
92CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.20897118
93YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.20704073
94CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.20143011
95MAF_26560356_Chip-Seq_TH2_Human1.19929090
96FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.18768272
97THAP11_20581084_ChIP-Seq_MESCs_Mouse1.18387110
98AR_21909140_ChIP-Seq_LNCAP_Human1.17851829
99NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.16720131
100E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.16273486
101CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.15963545
102HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.14660539
103P68_20966046_ChIP-Seq_HELA_Human1.14291452
104ELK1_19687146_ChIP-ChIP_HELA_Human1.14056269
105YY1_21170310_ChIP-Seq_MESCs_Mouse1.13978217
106DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.13504580
107KDM2B_26808549_Chip-Seq_SUP-B15_Human1.13368360
108ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.13157900
109UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.12835861
110SRY_22984422_ChIP-ChIP_TESTIS_Rat1.12635710
111STAT6_21828071_ChIP-Seq_BEAS2B_Human1.12529728
112KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.12381938
113HIF1A_21447827_ChIP-Seq_MCF-7_Human1.10068499
114IRF8_21731497_ChIP-ChIP_J774_Mouse1.09942181
115GATA1_22383799_ChIP-Seq_G1ME_Mouse1.09652438
116HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.09626640
117BRD4_27068464_Chip-Seq_AML-cells_Mouse1.09353514
118E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.08531892
119GATA2_22383799_ChIP-Seq_G1ME_Mouse1.07445600
120KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.07357145
121KDM2B_26808549_Chip-Seq_DND41_Human1.06828027
122KLF4_18555785_ChIP-Seq_MESCs_Mouse1.06151474
123KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.05821023
124NANOG_18555785_ChIP-Seq_MESCs_Mouse1.04995087
125SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.03894595
126TFEB_21752829_ChIP-Seq_HELA_Human1.03278060
127NCOR1_26117541_ChIP-Seq_K562_Human1.03188477
128CTCF_18555785_ChIP-Seq_MESCs_Mouse1.03095385
129DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.02354821
130IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.02075050
131CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.01319831
132KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.00508024
133SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.00386244
134POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.99671976
135RBPJ_22232070_ChIP-Seq_NCS_Mouse0.99582938
136FOXP1_21924763_ChIP-Seq_HESCs_Human0.98763969
137MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.98382108
138RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.96665898
139TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.96216745
140OCT4_18692474_ChIP-Seq_MEFs_Mouse0.94837816
141TBX5_21415370_ChIP-Seq_HL-1_Mouse0.94228704
142TP53_22127205_ChIP-Seq_IMR90_Human0.92740890
143TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91327869
144TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.91165110
145SA1_27219007_Chip-Seq_ERYTHROID_Human0.91129666
146CTCF_27219007_Chip-Seq_ERYTHROID_Human0.90664410

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system3.71728235
2MP0010094_abnormal_chromosome_stability3.58755252
3MP0003705_abnormal_hypodermis_morpholog3.15074282
4MP0003693_abnormal_embryo_hatching3.10362031
5MP0003077_abnormal_cell_cycle3.08306922
6MP0008057_abnormal_DNA_replication3.00248387
7MP0003763_abnormal_thymus_physiology2.94462504
8MP0003111_abnormal_nucleus_morphology2.91195490
9MP0004957_abnormal_blastocyst_morpholog2.90402123
10MP0005451_abnormal_body_composition2.86315076
11MP0002877_abnormal_melanocyte_morpholog2.82045457
12MP0004808_abnormal_hematopoietic_stem2.79961880
13MP0004185_abnormal_adipocyte_glucose2.74442504
14MP0010030_abnormal_orbit_morphology2.59418249
15MP0001835_abnormal_antigen_presentation2.58677748
16MP0008007_abnormal_cellular_replicative2.51803116
17MP0008058_abnormal_DNA_repair2.49953870
18MP0005671_abnormal_response_to2.44803939
19MP0004233_abnormal_muscle_weight2.44464249
20MP0002398_abnormal_bone_marrow2.35457180
21MP0000685_abnormal_immune_system2.32032497
22MP0001545_abnormal_hematopoietic_system2.27361203
23MP0005397_hematopoietic_system_phenotyp2.27361203
24MP0008877_abnormal_DNA_methylation2.19589095
25MP0001800_abnormal_humoral_immune2.15937372
26MP0002166_altered_tumor_susceptibility2.11184108
27MP0005058_abnormal_lysosome_morphology2.07691777
28MP0000678_abnormal_parathyroid_gland2.03308447
29MP0000703_abnormal_thymus_morphology2.02693496
30MP0005501_abnormal_skin_physiology1.96479925
31MP0000689_abnormal_spleen_morphology1.93313145
32MP0002722_abnormal_immune_system1.92578372
33MP0000490_abnormal_crypts_of1.92473111
34MP0008260_abnormal_autophagy1.88807814
35MP0009333_abnormal_splenocyte_physiolog1.87828389
36MP0002420_abnormal_adaptive_immunity1.83697934
37MP0002452_abnormal_antigen_presenting1.82029679
38MP0000566_synostosis1.80542481
39MP0001819_abnormal_immune_cell1.80413960
40MP0000716_abnormal_immune_system1.79148368
41MP0005257_abnormal_intraocular_pressure1.74231604
42MP0002429_abnormal_blood_cell1.72812552
43MP0002723_abnormal_immune_serum1.71781179
44MP0003453_abnormal_keratinocyte_physiol1.71507830
45MP0002006_tumorigenesis1.68892385
46MP0009785_altered_susceptibility_to1.68047399
47MP0002796_impaired_skin_barrier1.67364686
48MP0000537_abnormal_urethra_morphology1.64675384
49MP0005000_abnormal_immune_tolerance1.64653348
50MP0003436_decreased_susceptibility_to1.63709483
51MP0009278_abnormal_bone_marrow1.63114092
52MP0005174_abnormal_tail_pigmentation1.60676603
53MP0002019_abnormal_tumor_incidence1.60637642
54MP0002405_respiratory_system_inflammati1.60337978
55MP0000350_abnormal_cell_proliferation1.60333214
56MP0005025_abnormal_response_to1.56379834
57MP0005387_immune_system_phenotype1.52549134
58MP0001790_abnormal_immune_system1.52549134
59MP0001873_stomach_inflammation1.51405574
60MP0005410_abnormal_fertilization1.48352380
61MP0006054_spinal_hemorrhage1.46418255
62MP0000313_abnormal_cell_death1.44304500
63MP0003942_abnormal_urinary_system1.43487884
64MP0002249_abnormal_larynx_morphology1.42456479
65MP0005075_abnormal_melanosome_morpholog1.41635935
66MP0000465_gastrointestinal_hemorrhage1.38562811
67MP0001849_ear_inflammation1.38099321
68MP0001730_embryonic_growth_arrest1.35731853
69MP0010352_gastrointestinal_tract_polyps1.35280412
70MP0002089_abnormal_postnatal_growth/wei1.35130976
71MP0001929_abnormal_gametogenesis1.34864063
72MP0003866_abnormal_defecation1.34174164
73MP0005464_abnormal_platelet_physiology1.32778344
74MP0009053_abnormal_anal_canal1.31365061
75MP0001853_heart_inflammation1.29412735
76MP0004858_abnormal_nervous_system1.29254308
77MP0003566_abnormal_cell_adhesion1.27305987
78MP0010155_abnormal_intestine_physiology1.27005602
79MP0005666_abnormal_adipose_tissue1.24491831
80MP0002210_abnormal_sex_determination1.23507447
81MP0009672_abnormal_birth_weight1.20850712
82MP0003943_abnormal_hepatobiliary_system1.19261169
83MP0003786_premature_aging1.17339361
84MP0008932_abnormal_embryonic_tissue1.16518754
85MP0005375_adipose_tissue_phenotype1.15859445
86MP0000003_abnormal_adipose_tissue1.15835230
87MP0002080_prenatal_lethality1.12879749
88MP0000733_abnormal_muscle_development1.11714297
89MP0001216_abnormal_epidermal_layer1.10486142
90MP0001697_abnormal_embryo_size1.09712815
91MP0010307_abnormal_tumor_latency1.08839979
92MP0003303_peritoneal_inflammation1.08054563
93MP0003123_paternal_imprinting1.07112302
94MP0002095_abnormal_skin_pigmentation1.06890023
95MP0004947_skin_inflammation1.05451744
96MP0003806_abnormal_nucleotide_metabolis1.04504441
97MP0003941_abnormal_skin_development1.03743518
98MP0003172_abnormal_lysosome_physiology1.03728860
99MP0005623_abnormal_meninges_morphology1.03394361
100MP0002419_abnormal_innate_immunity1.02963249
101MP0001145_abnormal_male_reproductive1.02709327
102MP0004272_abnormal_basement_membrane0.98651279
103MP0001845_abnormal_inflammatory_respons0.98298326
104MP0010234_abnormal_vibrissa_follicle0.98283943
105MP0002132_abnormal_respiratory_system0.97895625
106MP0000762_abnormal_tongue_morphology0.97587414
107MP0004197_abnormal_fetal_growth/weight/0.96546629
108MP0001672_abnormal_embryogenesis/_devel0.96381235
109MP0005380_embryogenesis_phenotype0.96381235
110MP0003937_abnormal_limbs/digits/tail_de0.96306499
111MP0005409_darkened_coat_color0.96296108
112MP0006035_abnormal_mitochondrial_morpho0.96064305
113MP0002653_abnormal_ependyma_morphology0.96031254
114MP0002098_abnormal_vibrissa_morphology0.95990842
115MP0000858_altered_metastatic_potential0.95632000
116MP0002148_abnormal_hypersensitivity_rea0.95088026
117MP0000534_abnormal_ureter_morphology0.94641495
118MP0006292_abnormal_olfactory_placode0.93744693
119MP0003191_abnormal_cellular_cholesterol0.93730235
120MP0002092_abnormal_eye_morphology0.92298054
121MP0001881_abnormal_mammary_gland0.92091400
122MP0003186_abnormal_redox_activity0.91588233
123MP0000627_abnormal_mammary_gland0.90381592
124MP0003121_genomic_imprinting0.90135453
125MP0003698_abnormal_male_reproductive0.90012669
126MP0003567_abnormal_fetal_cardiomyocyte0.89029892
127MP0002163_abnormal_gland_morphology0.88925315
128MP0005076_abnormal_cell_differentiation0.87983878
129MP0003984_embryonic_growth_retardation0.87728343
130MP0000049_abnormal_middle_ear0.87358897
131MP0002697_abnormal_eye_size0.86878267
132MP0000653_abnormal_sex_gland0.85888921
133MP0002088_abnormal_embryonic_growth/wei0.85802140
134MP0002086_abnormal_extraembryonic_tissu0.85264109
135MP0002060_abnormal_skin_morphology0.85074464
136MP0002111_abnormal_tail_morphology0.83532565
137MP0004510_myositis0.83523717
138MP0002085_abnormal_embryonic_tissue0.83373286
139MP0000579_abnormal_nail_morphology0.82585564
140MP0009697_abnormal_copulation0.79988096
141MP0000750_abnormal_muscle_regeneration0.79812895
142MP0000428_abnormal_craniofacial_morphol0.79588791
143MP0000358_abnormal_cell_content/0.79126724
144MP0003935_abnormal_craniofacial_develop0.78913231
145MP0002084_abnormal_developmental_patter0.77921778
146MP0003315_abnormal_perineum_morphology0.77061385
147MP0009931_abnormal_skin_appearance0.76586003
148MP0000477_abnormal_intestine_morphology0.75494679
149MP0005023_abnormal_wound_healing0.73443070
150MP0002160_abnormal_reproductive_system0.72163282
151MP0002970_abnormal_white_adipose0.72084205
152MP0003385_abnormal_body_wall0.71987078
153MP0003115_abnormal_respiratory_system0.71850962
154MP0001119_abnormal_female_reproductive0.70633233
155MP0009379_abnormal_foot_pigmentation0.67962536
156MP0005384_cellular_phenotype0.66122900
157MP0005621_abnormal_cell_physiology0.64923968
158MP0000015_abnormal_ear_pigmentation0.64562252
159MP0001293_anophthalmia0.63700894
160MP0002161_abnormal_fertility/fecundity0.61216104
161MP0003300_gastrointestinal_ulcer0.60224245

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.86431019
2Abnormality of cells of the erythroid lineage (HP:0012130)4.85171958
3Abnormal number of erythroid precursors (HP:0012131)4.65426307
4Recurrent bronchitis (HP:0002837)4.06809331
5Aplasia/Hypoplasia of the sacrum (HP:0008517)3.91696578
6Thrombocytosis (HP:0001894)3.84353412
7Nasal polyposis (HP:0100582)3.69798669
8IgM deficiency (HP:0002850)3.64258346
9Broad distal phalanx of finger (HP:0009836)3.63646161
10Progressive muscle weakness (HP:0003323)3.43799962
11Panhypogammaglobulinemia (HP:0003139)3.41804346
12Elevated erythrocyte sedimentation rate (HP:0003565)3.33964765
13Abnormality of the nasal mucosa (HP:0000433)3.25293760
14Chronic otitis media (HP:0000389)3.25089701
15Aplastic anemia (HP:0001915)3.24953079
16Pallor (HP:0000980)3.24728013
17B lymphocytopenia (HP:0010976)3.21586612
18Abnormality of B cell number (HP:0010975)3.21586612
19Poikiloderma (HP:0001029)3.18597369
20Bronchitis (HP:0012387)3.05509138
21Achilles tendon contracture (HP:0001771)3.05217960
2211 pairs of ribs (HP:0000878)3.00764570
23Short nail (HP:0001799)2.96242698
24Recurrent viral infections (HP:0004429)2.95362844
25Deep palmar crease (HP:0006191)2.95155483
26Trismus (HP:0000211)2.77743271
27Basal cell carcinoma (HP:0002671)2.76121130
28Combined immunodeficiency (HP:0005387)2.71097033
29Abnormality of DNA repair (HP:0003254)2.69921265
30Abnormality of the Achilles tendon (HP:0005109)2.69681782
31Abnormality of T cells (HP:0002843)2.68516165
32Severe combined immunodeficiency (HP:0004430)2.67163805
33Macrocytic anemia (HP:0001972)2.64450376
34Selective tooth agenesis (HP:0001592)2.61629828
35Thyroiditis (HP:0100646)2.59063403
36Insomnia (HP:0100785)2.58648710
37Myelodysplasia (HP:0002863)2.58012073
38Chromsome breakage (HP:0040012)2.54634525
39Abnormality of cochlea (HP:0000375)2.54199462
40Overriding aorta (HP:0002623)2.53807141
41Overlapping toe (HP:0001845)2.50939300
42Lymphoma (HP:0002665)2.48773014
43Missing ribs (HP:0000921)2.47410025
44Abnormality of T cell physiology (HP:0011840)2.47211734
45Abnormal number of incisors (HP:0011064)2.46183524
46T lymphocytopenia (HP:0005403)2.43438249
47Diastasis recti (HP:0001540)2.41514289
48Agammaglobulinemia (HP:0004432)2.40374944
49Colon cancer (HP:0003003)2.39351526
50Renal duplication (HP:0000075)2.38739889
51Chromosomal breakage induced by crosslinking agents (HP:0003221)2.38180535
52Hypoplasia of the capital femoral epiphysis (HP:0003090)2.33009932
53Septate vagina (HP:0001153)2.31517832
54Facial cleft (HP:0002006)2.29518580
55Prominent nose (HP:0000448)2.29102454
56Prolonged bleeding time (HP:0003010)2.28084105
57Vertebral compression fractures (HP:0002953)2.27564063
58Hypoplasia of the thymus (HP:0000778)2.26012999
59Abnormality of the anterior horn cell (HP:0006802)2.25055710
60Degeneration of anterior horn cells (HP:0002398)2.25055710
61Optic nerve coloboma (HP:0000588)2.24844059
62Gastrointestinal stroma tumor (HP:0100723)2.24719202
63IgG deficiency (HP:0004315)2.24540403
64Abnormality of the fingertips (HP:0001211)2.24498088
65Abnormality of chromosome stability (HP:0003220)2.23593064
66Microglossia (HP:0000171)2.22482058
67Abnormality of T cell number (HP:0011839)2.21820761
68Ulnar bowing (HP:0003031)2.21612526
69Abnormality of the phalanges of the hallux (HP:0010057)2.19391431
70Entropion (HP:0000621)2.19367946
71Recurrent sinusitis (HP:0011108)2.18707095
72Lymphopenia (HP:0001888)2.18238551
73Deviation of the thumb (HP:0009603)2.17375985
74Rough bone trabeculation (HP:0100670)2.17339891
75Elfin facies (HP:0004428)2.16286785
76Recurrent fungal infections (HP:0002841)2.15583377
77Premature rupture of membranes (HP:0001788)2.15005164
78Abnormality of cells of the lymphoid lineage (HP:0012140)2.14520506
79Acute myeloid leukemia (HP:0004808)2.14430606
80Abnormality of the distal phalanges of the toes (HP:0010182)2.14018715
81Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.13224794
82Short 4th metacarpal (HP:0010044)2.13224794
83Cerebellar dysplasia (HP:0007033)2.12952314
84Breast hypoplasia (HP:0003187)2.12762070
85Small epiphyses (HP:0010585)2.12566646
86Oral leukoplakia (HP:0002745)2.12114166
87Abnormality of the calcaneus (HP:0008364)2.12062834
88Recurrent abscess formation (HP:0002722)2.11100402
89Medulloblastoma (HP:0002885)2.08595968
90Amaurosis fugax (HP:0100576)2.07699710
91Squamous cell carcinoma (HP:0002860)2.07469001
92Proximal placement of thumb (HP:0009623)2.06371314
93Mediastinal lymphadenopathy (HP:0100721)2.05979191
94Increased nuchal translucency (HP:0010880)2.05710056
95Microretrognathia (HP:0000308)2.04162105
96Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.03497708
97Decreased activity of mitochondrial respiratory chain (HP:0008972)2.03497708
98Cellulitis (HP:0100658)2.02876903
99Bicuspid aortic valve (HP:0001647)2.01742318
100Natal tooth (HP:0000695)2.01349482
101Broad face (HP:0000283)2.00473421
102Ragged-red muscle fibers (HP:0003200)2.00410152
103Deep venous thrombosis (HP:0002625)2.00222090
104Abnormality of the preputium (HP:0100587)1.99708749
105Distal lower limb amyotrophy (HP:0008944)1.99067157
106Gonadotropin excess (HP:0000837)1.98658246
107Flat acetabular roof (HP:0003180)1.98440796
108Broad palm (HP:0001169)1.97095534
109Acute lymphatic leukemia (HP:0006721)1.94897562
110Myositis (HP:0100614)1.94354629
111Abnormality of reticulocytes (HP:0004312)1.93966787
112Fatigue (HP:0012378)1.93092638
113Bronchiectasis (HP:0002110)1.92770503
114Severe visual impairment (HP:0001141)1.92088475
115Disproportionate tall stature (HP:0001519)1.91858276
116Aplasia/Hypoplasia of the thymus (HP:0010515)1.91585179
117Recurrent otitis media (HP:0000403)1.91420350
118High anterior hairline (HP:0009890)1.91301100
119Abnormality of the distal phalanx of the thumb (HP:0009617)1.90773578
120Chronic sinusitis (HP:0011109)1.90316377
121Absent rod-and cone-mediated responses on ERG (HP:0007688)1.90213479
122Patellar dislocation (HP:0002999)1.90120240
123Bone marrow hypocellularity (HP:0005528)1.89911462
124Asplenia (HP:0001746)1.88664810
125Hydroureter (HP:0000072)1.88314307
126Ependymoma (HP:0002888)1.88183612
127Protrusio acetabuli (HP:0003179)1.88179245
128Absent epiphyses (HP:0010577)1.87389457
129Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.87389457
130Flared metaphyses (HP:0003015)1.87315792
131High pitched voice (HP:0001620)1.86570540
132Petechiae (HP:0000967)1.85954676
133Elbow flexion contracture (HP:0002987)1.85465365
134Multiple enchondromatosis (HP:0005701)1.85438957
135Asymmetry of the thorax (HP:0001555)1.85124892
136Facial hemangioma (HP:0000329)1.83952988
137Exertional dyspnea (HP:0002875)1.83068130
138Spinal cord compression (HP:0002176)1.82870009
139Flattened epiphyses (HP:0003071)1.82684172
140Premature skin wrinkling (HP:0100678)1.82558347
141Meckel diverticulum (HP:0002245)1.82422606
142Viral hepatitis (HP:0006562)1.81616217
143Abnormality of the thoracic spine (HP:0100711)1.80611911
144Abnormal trabecular bone morphology (HP:0100671)1.80443090
145Abnormality of the umbilical cord (HP:0010881)1.79892498
146Pancytopenia (HP:0001876)1.79845051
147Absent thumb (HP:0009777)1.79103047
148Abnormality of the ileum (HP:0001549)1.79043560
149Leukopenia (HP:0001882)1.77698780
150Emphysema (HP:0002097)1.77678914
151Gastrointestinal inflammation (HP:0004386)1.77392072
152Microvesicular hepatic steatosis (HP:0001414)1.77217258
153Abnormality of eosinophils (HP:0001879)1.75449720
154Colitis (HP:0002583)1.74762218
155Biconcave vertebral bodies (HP:0004586)1.74306262
156Distal upper limb amyotrophy (HP:0007149)1.74279539
157Upper limb amyotrophy (HP:0009129)1.74279539
158Recurrent bacterial skin infections (HP:0005406)1.74145026
159Agnosia (HP:0010524)1.73491154
160Hyperacusis (HP:0010780)1.72813233
161Athetosis (HP:0002305)1.72114434
162Meningitis (HP:0001287)1.72062657
163Progressive external ophthalmoplegia (HP:0000590)1.72035457
164Verrucae (HP:0200043)1.71996251
165Atresia of the external auditory canal (HP:0000413)1.70617404
166Long palpebral fissure (HP:0000637)1.70610586
167Delayed epiphyseal ossification (HP:0002663)1.70309959
168Aplasia/Hypoplasia of the patella (HP:0006498)1.70050238
169Patellar aplasia (HP:0006443)1.69586333
170Renovascular hypertension (HP:0100817)1.68986707
171Morphological abnormality of the inner ear (HP:0011390)1.68816946
172Nasolacrimal duct obstruction (HP:0000579)1.68692423
173Partial duplication of the phalanx of hand (HP:0009999)1.68662406
174Shallow orbits (HP:0000586)1.65395928
175Reticulocytosis (HP:0001923)1.64441820
176Abnormality of the tricuspid valve (HP:0001702)1.64385217
177Bowing of the arm (HP:0006488)1.62215681
178Bowed forearm bones (HP:0003956)1.62215681
179Abnormality of carpal bone ossification (HP:0006257)1.60701454
180Duplication of thumb phalanx (HP:0009942)1.59885050
181Limited elbow extension (HP:0001377)1.59394461
182Horseshoe kidney (HP:0000085)1.59189237
183Self-mutilation (HP:0000742)1.57639061

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK33.77017526
2MAP4K13.33431622
3EPHA23.28266792
4MAP3K102.94184265
5WEE12.84190181
6EEF2K2.82305071
7NEK22.64614085
8SMG12.61494551
9SIK12.60894131
10CDC72.38357659
11KIT2.31107008
12BUB12.13093149
13TGFBR11.99944898
14PASK1.96622726
15BRD41.94156467
16NME21.91301439
17TAOK21.82243229
18DYRK31.80981685
19FLT31.78667547
20MST1R1.72967022
21EIF2AK11.70223005
22ZAP701.63145983
23TEC1.61113818
24PKN21.57770554
25RPS6KA41.56598705
26JAK31.56580420
27ARAF1.55392304
28STK161.52496068
29CSF1R1.52136633
30LRRK21.49810076
31BTK1.48694602
32ACVR1B1.48266544
33ATR1.47625356
34CSNK1G31.43076669
35RPS6KB21.41528620
36CDK71.36302195
37LATS21.36279390
38CDK41.34431071
39PRPF4B1.33228679
40GRK61.31953729
41CSNK1A1L1.31862930
42TLK11.28820153
43STK101.28600699
44BRAF1.25959294
45MAP2K31.25777983
46STK38L1.24196541
47CDK121.23101708
48RIPK11.21617877
49TESK21.21339949
50PIM21.19275479
51PTK21.18266447
52BLK1.18104769
53SYK1.17781446
54ABL21.16198054
55PIM11.13870060
56PLK11.12901498
57AURKA1.10992852
58VRK21.10482714
59PBK1.10277716
60STK41.08349315
61VRK11.07611196
62CCNB11.06063180
63TYK21.06004242
64MET1.05111622
65SCYL21.04307713
66TBK11.03750489
67PDGFRA1.01148994
68AURKB1.01056216
69MTOR0.98051447
70BRSK20.95848639
71SRPK10.95770216
72TESK10.94352670
73IRAK20.94073018
74CSNK1G10.93368520
75SIK20.92254242
76CSNK1G20.91714384
77STK380.91541914
78NEK10.89225028
79PDK40.88538294
80PDK30.88538294
81CHUK0.82205947
82DMPK0.80827865
83YES10.79849875
84CHEK10.79582484
85KDR0.79335215
86ERN10.79262285
87MATK0.78553036
88CHEK20.77542758
89TTK0.76740638
90FGFR40.76433425
91PRKD20.76095445
92MAP3K80.75499795
93CDK60.74763018
94ITK0.73407036
95DYRK1B0.71702857
96LCK0.70534897
97TXK0.70489688
98TRIB30.70140071
99BRSK10.69813618
100CLK10.68894501
101EIF2AK30.67681571
102MAP3K30.67622239
103LYN0.66849124
104IKBKB0.66817274
105PAK40.65815565
106MAPK110.65724717
107MAP3K90.65573569
108PIK3CG0.65305267
109ILK0.64484647
110TTN0.64171064
111TSSK60.63006053
112PRKCI0.60528750
113MOS0.59990013
114TGFBR20.59868798
115NTRK10.59520979
116TYRO30.58058333
117IRAK40.57520013
118CDK80.57422205
119LMTK20.57338934
120SIK30.57258748
121EPHB20.55876426
122KSR20.55791821
123PTK60.54616579
124MAP3K110.54001876
125PDPK10.53752538
126IKBKE0.53741983
127ICK0.53273282
128RAF10.51828024
129PLK40.50404453
130ERBB40.50155746
131CSK0.49942704
132FES0.49873658
133AKT20.49751013
134BCKDK0.49700909
135MKNK10.48862828
136TAOK10.48047953
137HCK0.46240368
138RPS6KA60.46231880
139CDK20.46072393
140LATS10.45446265
141TAF10.44504731
142ATM0.44308380
143WNK10.44001816
144CDK11A0.42689756
145MARK20.41853873
146BMX0.40234699
147CDK10.39691135
148PRKG20.39678250
149MAPKAPK30.38526096
150DDR20.38104545
151LIMK10.37741417

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.53079140
2Ribosome_Homo sapiens_hsa030103.66583187
3Mismatch repair_Homo sapiens_hsa034303.49618570
4Base excision repair_Homo sapiens_hsa034102.87618563
5Spliceosome_Homo sapiens_hsa030402.75415352
6Primary immunodeficiency_Homo sapiens_hsa053402.48189928
7RNA transport_Homo sapiens_hsa030132.23303556
8Cell cycle_Homo sapiens_hsa041102.20236518
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.19233394
10Homologous recombination_Homo sapiens_hsa034402.17563010
11Nucleotide excision repair_Homo sapiens_hsa034202.17448345
12Pyrimidine metabolism_Homo sapiens_hsa002401.95528577
13Non-homologous end-joining_Homo sapiens_hsa034501.90724422
14RNA polymerase_Homo sapiens_hsa030201.82101975
15Bladder cancer_Homo sapiens_hsa052191.77538459
16B cell receptor signaling pathway_Homo sapiens_hsa046621.74007456
17Fanconi anemia pathway_Homo sapiens_hsa034601.70939296
18Antigen processing and presentation_Homo sapiens_hsa046121.64152127
19mRNA surveillance pathway_Homo sapiens_hsa030151.63475657
20Herpes simplex infection_Homo sapiens_hsa051681.61371271
21RNA degradation_Homo sapiens_hsa030181.54889485
22Biosynthesis of amino acids_Homo sapiens_hsa012301.53091843
23One carbon pool by folate_Homo sapiens_hsa006701.48256005
24Galactose metabolism_Homo sapiens_hsa000521.45186972
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.42104936
26Measles_Homo sapiens_hsa051621.41605592
27p53 signaling pathway_Homo sapiens_hsa041151.41131666
28Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.38375956
29Proteasome_Homo sapiens_hsa030501.36548418
30Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.31608376
31Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.31506854
32T cell receptor signaling pathway_Homo sapiens_hsa046601.28816535
33Epstein-Barr virus infection_Homo sapiens_hsa051691.28458170
34Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.27852834
35NF-kappa B signaling pathway_Homo sapiens_hsa040641.27508894
36Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.26961616
37Leishmaniasis_Homo sapiens_hsa051401.22663384
38Fructose and mannose metabolism_Homo sapiens_hsa000511.22418814
392-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.21837786
40Viral carcinogenesis_Homo sapiens_hsa052031.19098506
41Basal transcription factors_Homo sapiens_hsa030221.16547365
42HTLV-I infection_Homo sapiens_hsa051661.15573281
43Hematopoietic cell lineage_Homo sapiens_hsa046401.13968365
44Other glycan degradation_Homo sapiens_hsa005111.12262655
45Acute myeloid leukemia_Homo sapiens_hsa052211.08882718
46Transcriptional misregulation in cancer_Homo sapiens_hsa052021.08678872
47Chronic myeloid leukemia_Homo sapiens_hsa052201.05394422
48Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.04661605
49Shigellosis_Homo sapiens_hsa051311.04245418
50Systemic lupus erythematosus_Homo sapiens_hsa053221.02724832
51RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.98946076
52N-Glycan biosynthesis_Homo sapiens_hsa005100.98724608
53Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.98550854
54Sulfur relay system_Homo sapiens_hsa041220.97461973
55Small cell lung cancer_Homo sapiens_hsa052220.94671180
56Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.94531535
57Carbon metabolism_Homo sapiens_hsa012000.94239377
58Osteoclast differentiation_Homo sapiens_hsa043800.94216316
59Purine metabolism_Homo sapiens_hsa002300.93049304
60Influenza A_Homo sapiens_hsa051640.92193977
61Intestinal immune network for IgA production_Homo sapiens_hsa046720.91795756
62Toxoplasmosis_Homo sapiens_hsa051450.91281208
63Hepatitis B_Homo sapiens_hsa051610.88355248
64Apoptosis_Homo sapiens_hsa042100.87405883
65Legionellosis_Homo sapiens_hsa051340.87107274
66Renal cell carcinoma_Homo sapiens_hsa052110.83045789
67Jak-STAT signaling pathway_Homo sapiens_hsa046300.82215543
68Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.81752646
69Colorectal cancer_Homo sapiens_hsa052100.80603947
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.80190754
71Vitamin B6 metabolism_Homo sapiens_hsa007500.80029117
72NOD-like receptor signaling pathway_Homo sapiens_hsa046210.79719661
73Hippo signaling pathway_Homo sapiens_hsa043900.77086140
74Viral myocarditis_Homo sapiens_hsa054160.75538807
75Pentose phosphate pathway_Homo sapiens_hsa000300.75492437
76Pancreatic cancer_Homo sapiens_hsa052120.74246407
77Non-small cell lung cancer_Homo sapiens_hsa052230.71939897
78Oocyte meiosis_Homo sapiens_hsa041140.71189151
79Platelet activation_Homo sapiens_hsa046110.70194929
80Thyroid cancer_Homo sapiens_hsa052160.69745215
81Endometrial cancer_Homo sapiens_hsa052130.69665045
82Notch signaling pathway_Homo sapiens_hsa043300.68591141
83Proteoglycans in cancer_Homo sapiens_hsa052050.67574331
84Prion diseases_Homo sapiens_hsa050200.67466756
85Adherens junction_Homo sapiens_hsa045200.67443964
86Pyruvate metabolism_Homo sapiens_hsa006200.67157365
87Toll-like receptor signaling pathway_Homo sapiens_hsa046200.65496324
88Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63873565
89Prostate cancer_Homo sapiens_hsa052150.63079895
90MicroRNAs in cancer_Homo sapiens_hsa052060.62123307
91Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61934811
92VEGF signaling pathway_Homo sapiens_hsa043700.61246893
93Glioma_Homo sapiens_hsa052140.60933504
94Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.60696837
95ErbB signaling pathway_Homo sapiens_hsa040120.60549655
96Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.59126493
97Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.58082675
98Cysteine and methionine metabolism_Homo sapiens_hsa002700.58061691
99Hepatitis C_Homo sapiens_hsa051600.57725066
100Melanoma_Homo sapiens_hsa052180.56830801
101Basal cell carcinoma_Homo sapiens_hsa052170.56741687
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56348554
103Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.56274205
104Huntingtons disease_Homo sapiens_hsa050160.55467083
105Neurotrophin signaling pathway_Homo sapiens_hsa047220.54483285
106Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.54471259
107Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.53418021
108Insulin signaling pathway_Homo sapiens_hsa049100.51843385
109AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.51661845
110Hedgehog signaling pathway_Homo sapiens_hsa043400.51454905
111Selenocompound metabolism_Homo sapiens_hsa004500.48982761
112Leukocyte transendothelial migration_Homo sapiens_hsa046700.48276174
113Salmonella infection_Homo sapiens_hsa051320.47621381
114TNF signaling pathway_Homo sapiens_hsa046680.46804724
115Central carbon metabolism in cancer_Homo sapiens_hsa052300.46512218
116Wnt signaling pathway_Homo sapiens_hsa043100.44912488
117Cyanoamino acid metabolism_Homo sapiens_hsa004600.44282106
118Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.42052638
119Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.41942663
120Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.41131100
121Alcoholism_Homo sapiens_hsa050340.41118744
122HIF-1 signaling pathway_Homo sapiens_hsa040660.40578618
123Prolactin signaling pathway_Homo sapiens_hsa049170.39756832
124Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39259224
125Vibrio cholerae infection_Homo sapiens_hsa051100.38400409
126Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.37854073
127Drug metabolism - other enzymes_Homo sapiens_hsa009830.37287704
128Pathways in cancer_Homo sapiens_hsa052000.37201813
129Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.36883260
130mTOR signaling pathway_Homo sapiens_hsa041500.36779993
131Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.35035117
132Lysine degradation_Homo sapiens_hsa003100.34444398
133Allograft rejection_Homo sapiens_hsa053300.32647425
134Chemokine signaling pathway_Homo sapiens_hsa040620.31949069
135Tuberculosis_Homo sapiens_hsa051520.31760219
136Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.31721534
137Folate biosynthesis_Homo sapiens_hsa007900.29739945
138Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.29718058

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