MROH1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of integrin activation (GO:0033623)4.97808306
2macroautophagy (GO:0016236)4.37515154
3proline biosynthetic process (GO:0006561)4.35027980
4semaphorin-plexin signaling pathway (GO:0071526)4.19965604
5apoptotic cell clearance (GO:0043277)4.13183909
6modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.59622659
7positive regulation by organism of defense response of other organism involved in symbiotic interact3.59622659
8modulation by symbiont of host immune response (GO:0052553)3.59622659
9positive regulation by symbiont of host defense response (GO:0052509)3.59622659
10modulation by symbiont of host defense response (GO:0052031)3.59622659
11modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.59622659
12negative regulation of erythrocyte differentiation (GO:0045647)3.56313612
13positive regulation of protein homooligomerization (GO:0032464)3.35159238
14mannose metabolic process (GO:0006013)3.34012816
15positive regulation of p38MAPK cascade (GO:1900745)3.16785212
16cell-cell junction maintenance (GO:0045217)3.14659708
17endothelial cell chemotaxis (GO:0035767)3.14589507
18regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.14432881
19protein localization to endosome (GO:0036010)3.08593305
20L-alpha-amino acid transmembrane transport (GO:1902475)3.07582451
21proline metabolic process (GO:0006560)3.06214818
22positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.02112619
23regulation of interferon-beta biosynthetic process (GO:0045357)3.01020705
24positive regulation of receptor recycling (GO:0001921)3.00064176
25macrophage activation involved in immune response (GO:0002281)2.94924789
26positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.91675505
27regulation of protein polyubiquitination (GO:1902914)2.88929766
28positive regulation of Cdc42 GTPase activity (GO:0043089)2.87239347
29negative regulation of fatty acid transport (GO:2000192)2.85991561
30desmosome organization (GO:0002934)2.84734756
31negative regulation of cell size (GO:0045792)2.83264036
32regulation of protein homooligomerization (GO:0032462)2.80484446
33positive regulation of protein kinase C signaling (GO:0090037)2.80036550
34embryonic placenta development (GO:0001892)2.76323015
35synaptic vesicle endocytosis (GO:0048488)2.75991222
36regulation of ARF GTPase activity (GO:0032312)2.75641045
37negative regulation of granulocyte differentiation (GO:0030853)2.75196699
38phospholipid homeostasis (GO:0055091)2.74892820
39positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.71716119
40response to muramyl dipeptide (GO:0032495)2.71337208
41embryonic process involved in female pregnancy (GO:0060136)2.69674131
42barbed-end actin filament capping (GO:0051016)2.67994081
43regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.67621340
44activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.66481071
45regulation of NFAT protein import into nucleus (GO:0051532)2.64483960
46hemidesmosome assembly (GO:0031581)2.63437825
47regulation of cholesterol homeostasis (GO:2000188)2.62314185
48plasma membrane repair (GO:0001778)2.62138932
49cell adhesion mediated by integrin (GO:0033627)2.59917122
50regulation of early endosome to late endosome transport (GO:2000641)2.59706707
51response to peptidoglycan (GO:0032494)2.58733703
52cellular response to ATP (GO:0071318)2.57974482
53negative regulation of cell killing (GO:0031342)2.57570594
54negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.57570594
55regulation of cholesterol storage (GO:0010885)2.57390073
56regulation of p38MAPK cascade (GO:1900744)2.56079858
57germinal center formation (GO:0002467)2.54822290
58positive regulation of CREB transcription factor activity (GO:0032793)2.54494150
59cell junction maintenance (GO:0034331)2.52594967
60maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.52247332
61receptor catabolic process (GO:0032801)2.52024765
62I-kappaB phosphorylation (GO:0007252)2.50464804
63activation of Rac GTPase activity (GO:0032863)2.50235006
64alanine transport (GO:0032328)2.48881273
65lysosome organization (GO:0007040)2.48339086
66lytic vacuole organization (GO:0080171)2.48339086
67cell volume homeostasis (GO:0006884)2.47849449
68regulation of ARF protein signal transduction (GO:0032012)2.47377410
69positive regulation of protein dephosphorylation (GO:0035307)2.47267165
70negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.46955784
71regulation of podosome assembly (GO:0071801)2.46669410
72synaptic vesicle docking involved in exocytosis (GO:0016081)2.46062037
73cell-substrate junction assembly (GO:0007044)2.45501442
74adherens junction assembly (GO:0034333)2.44801631
75lipoprotein transport (GO:0042953)2.44302406
76positive regulation of Rac GTPase activity (GO:0032855)2.43901478
77positive regulation of nuclease activity (GO:0032075)2.42377182
78signal complex assembly (GO:0007172)2.42197664
79endocytic recycling (GO:0032456)2.41673840
80phosphatidylglycerol biosynthetic process (GO:0006655)2.40675029
81regulation of clathrin-mediated endocytosis (GO:2000369)2.39888809
82regulation of hydrogen peroxide metabolic process (GO:0010310)2.39682741
83apoptotic process involved in morphogenesis (GO:0060561)2.39556704
84negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.38937638
85response to manganese ion (GO:0010042)2.38839597
86positive regulation of cell adhesion mediated by integrin (GO:0033630)2.38481765
87regulation of water loss via skin (GO:0033561)2.38283482
88positive regulation of protein deacetylation (GO:0090312)2.37847492
89protein retention in ER lumen (GO:0006621)2.37626284
90establishment of apical/basal cell polarity (GO:0035089)2.37378398
91cell-substrate adherens junction assembly (GO:0007045)2.36625140
92focal adhesion assembly (GO:0048041)2.36625140
93regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.36516102
94positive regulation of leukocyte degranulation (GO:0043302)2.35586290
95positive regulation of protein oligomerization (GO:0032461)2.33158927
96regulation of myeloid leukocyte mediated immunity (GO:0002886)2.32466679
97epithelial cell-cell adhesion (GO:0090136)2.31859292
98response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.31092138
99response to host immune response (GO:0052572)2.31092138
100positive regulation of cholesterol efflux (GO:0010875)2.29725583
101negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.29118653
102positive regulation of histone deacetylation (GO:0031065)2.27052096
103response to laminar fluid shear stress (GO:0034616)2.26573336
104negative regulation of interleukin-8 production (GO:0032717)2.25645407
105insulin-like growth factor receptor signaling pathway (GO:0048009)2.23720979
106endoplasmic reticulum unfolded protein response (GO:0030968)2.23337085
107negative regulation of viral release from host cell (GO:1902187)2.23236672
108regulation of translational fidelity (GO:0006450)2.21868417
109regulation of membrane protein ectodomain proteolysis (GO:0051043)2.21573052
110adenosine receptor signaling pathway (GO:0001973)2.20783392
111response to fluid shear stress (GO:0034405)2.20716475
112activation of MAPKKK activity (GO:0000185)2.20492217
113positive regulation of gamma-delta T cell activation (GO:0046645)2.19672312
114NIK/NF-kappaB signaling (GO:0038061)2.19657390
115regulation of fatty acid beta-oxidation (GO:0031998)2.19600372
116peptidyl-tyrosine autophosphorylation (GO:0038083)2.19338283
117thymic T cell selection (GO:0045061)2.18184831
118regulation of T-helper 2 cell differentiation (GO:0045628)2.17178281
119cellular response to unfolded protein (GO:0034620)2.16998227
120stress fiber assembly (GO:0043149)2.16995124
121regulation of regulated secretory pathway (GO:1903305)2.16587528
122regulation of extracellular matrix disassembly (GO:0010715)2.16312668
123Rho protein signal transduction (GO:0007266)2.16227837
124cellular response to fluid shear stress (GO:0071498)2.16108447
125regulation of nuclease activity (GO:0032069)2.15802604
126activation of JUN kinase activity (GO:0007257)2.15378342
127regulation of mast cell degranulation (GO:0043304)2.14899321
128positive thymic T cell selection (GO:0045059)2.14043642
129actin filament bundle assembly (GO:0051017)2.13767422
130actin filament bundle organization (GO:0061572)2.13767422
131regulation of hydrogen peroxide-induced cell death (GO:1903205)2.13598677
132dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.13102056
133regulation of leukocyte degranulation (GO:0043300)2.13090848
134low-density lipoprotein particle clearance (GO:0034383)2.12881344
135positive regulation of Rap GTPase activity (GO:0032854)2.12574383
136response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.12081149
137response to host (GO:0075136)2.12081149
138response to host defenses (GO:0052200)2.12081149
139negative regulation of stress fiber assembly (GO:0051497)2.11750861
140neutrophil mediated immunity (GO:0002446)2.11714305
141cytoskeletal anchoring at plasma membrane (GO:0007016)2.11569410
142regulation of type I interferon-mediated signaling pathway (GO:0060338)2.10583597
143regulation of bone resorption (GO:0045124)2.10469404
144positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.10425656
145negative regulation of myotube differentiation (GO:0010832)2.10283101
146mitotic G1 DNA damage checkpoint (GO:0031571)2.10084645
147negative regulation of macroautophagy (GO:0016242)2.09831066
148positive regulation of Rho GTPase activity (GO:0032321)2.09646978
149regulation of protein oligomerization (GO:0032459)2.09510877
150retrograde transport, endosome to Golgi (GO:0042147)2.09475939
151GDP-mannose metabolic process (GO:0019673)2.09223672
152atrioventricular valve morphogenesis (GO:0003181)2.08271679
153vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.07276999
154modulation by symbiont of host cellular process (GO:0044068)2.06758294
155positive regulation of cellular amide metabolic process (GO:0034250)2.06278120
156regulation of response to reactive oxygen species (GO:1901031)2.05950793
157negative regulation of interleukin-12 production (GO:0032695)2.05898904
158negative regulation of Ras GTPase activity (GO:0034261)2.05751689
159sodium ion export (GO:0071436)2.05723978
160ER-nucleus signaling pathway (GO:0006984)2.05031445
161positive regulation of leukocyte apoptotic process (GO:2000108)2.04771840
162detection of molecule of bacterial origin (GO:0032490)2.04585713
163establishment of skin barrier (GO:0061436)2.03985449
164lipopolysaccharide-mediated signaling pathway (GO:0031663)2.03524147
165negative regulation of toll-like receptor signaling pathway (GO:0034122)2.03473880
166N-acetylneuraminate metabolic process (GO:0006054)2.01770023
167cellular response to virus (GO:0098586)2.00950403
168epithelial cell differentiation involved in prostate gland development (GO:0060742)2.00829989
169regulation of ruffle assembly (GO:1900027)2.00455303
170histone H4 deacetylation (GO:0070933)1.98076127
171negative regulation of amyloid precursor protein catabolic process (GO:1902992)1.97181023

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.61384813
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.58233783
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.26649105
4LXR_22292898_ChIP-Seq_THP-1_Human2.25751157
5SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.23631763
6Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.20913148
7KDM2B_26808549_Chip-Seq_SUP-B15_Human2.15192281
8THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.97193638
9IRF8_22096565_ChIP-ChIP_GC-B_Human1.96356736
10SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.94004621
11CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.90198888
12ESR2_21235772_ChIP-Seq_MCF-7_Human1.84336073
13VDR_21846776_ChIP-Seq_THP-1_Human1.83293357
14KDM2B_26808549_Chip-Seq_DND41_Human1.81618871
15TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.77053001
16KDM2B_26808549_Chip-Seq_K562_Human1.76486685
17NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.74692851
18ESR1_21235772_ChIP-Seq_MCF-7_Human1.73729900
19IRF8_27001747_Chip-Seq_BMDM_Mouse1.71285651
20TCF7_22412390_ChIP-Seq_EML_Mouse1.70897753
21SPI1_23127762_ChIP-Seq_K562_Human1.68019788
22MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.64981017
23RARG_19884340_ChIP-ChIP_MEFs_Mouse1.64267595
24NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.63202377
25KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.61714322
26LXR_22158963_ChIP-Seq_LIVER_Mouse1.61235913
27KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.61203879
28RACK7_27058665_Chip-Seq_MCF-7_Human1.59806316
29VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.58205636
30E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.53865866
31RXR_22158963_ChIP-Seq_LIVER_Mouse1.51682500
32DROSHA_22980978_ChIP-Seq_HELA_Human1.47579108
33UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.47362916
34SA1_27219007_Chip-Seq_ERYTHROID_Human1.46745011
35DNAJC2_21179169_ChIP-ChIP_NT2_Human1.46452995
36PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.43888176
37CTCF_27219007_Chip-Seq_Bcells_Human1.43082160
38ELK3_25401928_ChIP-Seq_HUVEC_Human1.42670786
39SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.42478968
40BCL6_27268052_Chip-Seq_Bcells_Human1.40323529
41GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.39522996
42BRD4_27068464_Chip-Seq_AML-cells_Mouse1.39043066
43RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.38716575
44PPARA_22158963_ChIP-Seq_LIVER_Mouse1.38578267
45SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.37854363
46IRF8_21731497_ChIP-ChIP_J774_Mouse1.37255577
47ERG_21242973_ChIP-ChIP_JURKAT_Human1.36674187
48FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.35940051
49P300_27058665_Chip-Seq_ZR-75-30cells_Human1.35564715
50STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.34937056
51NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.32136236
52EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.31785638
53MAF_26560356_Chip-Seq_TH2_Human1.31520859
54GATA2_21666600_ChIP-Seq_HMVEC_Human1.30054304
55SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.29728805
56ELF1_20517297_ChIP-Seq_JURKAT_Human1.29492174
57ZFP281_27345836_Chip-Seq_ESCs_Mouse1.29104733
58IKZF1_21737484_ChIP-ChIP_HCT116_Human1.28543866
59ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.28329053
60RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.27801343
61P63_26484246_Chip-Seq_KERATINOCYTES_Human1.27452019
62NFIB_24661679_ChIP-Seq_LUNG_Mouse1.27372641
63SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.25650213
64VDR_24763502_ChIP-Seq_THP-1_Human1.24953649
65RUNX1_22412390_ChIP-Seq_EML_Mouse1.22944609
66CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.22616636
67TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.22343809
68KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.22330293
69ESR1_20079471_ChIP-ChIP_T-47D_Human1.21667838
70ZNF263_19887448_ChIP-Seq_K562_Human1.20251110
71KDM2B_26808549_Chip-Seq_JURKAT_Human1.19479022
72MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.19084474
73EGR1_19374776_ChIP-ChIP_THP-1_Human1.19005884
74TP63_17297297_ChIP-ChIP_HaCaT_Human1.17901358
75UTX_26944678_Chip-Seq_JUKART_Human1.17892046
76RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.17705647
77KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16265079
78DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.15865621
79ZFP281_18757296_ChIP-ChIP_E14_Mouse1.15719850
80GATA1_19941827_ChIP-Seq_MEL_Mouse1.15188030
81SCL_19346495_ChIP-Seq_HPC-7_Human1.14194524
82WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.12189310
83E2F1_20622854_ChIP-Seq_HELA_Human1.10963882
84GATA1_19941826_ChIP-Seq_K562_Human1.10248412
85FOXA2_19822575_ChIP-Seq_HepG2_Human1.09443107
86PHF8_20622854_ChIP-Seq_HELA_Human1.09125334
87MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.07714391
88ATF3_27146783_Chip-Seq_COLON_Human1.07649074
89SRY_22984422_ChIP-ChIP_TESTIS_Rat1.07611200
90PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.07046758
91SMC4_20622854_ChIP-Seq_HELA_Human1.07034606
92TP53_22127205_ChIP-Seq_IMR90_Human1.06865238
93SOX9_24532713_ChIP-Seq_HFSC_Mouse1.06842881
94RUNX1_27514584_Chip-Seq_MCF-7_Human1.05661253
95MYB_21317192_ChIP-Seq_ERMYB_Mouse1.05196751
96OCT4_19829295_ChIP-Seq_ESCs_Human1.04253279
97RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04230980
98TBX20_22328084_ChIP-Seq_HEART_Mouse1.03417028
99TBX20_22080862_ChIP-Seq_HEART_Mouse1.03417028
100RARB_24833708_ChIP-Seq_LIVER_Mouse1.02907845
101PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.01886367
102TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.01815428
103MYC_22102868_ChIP-Seq_BL_Human1.00825534
104NCOR1_26117541_ChIP-Seq_K562_Human0.99962180
105SOX2_27498859_Chip-Seq_STOMACH_Mouse0.98902302
106TRIM28_21343339_ChIP-Seq_HEK293_Human0.98394902
107SA1_27219007_Chip-Seq_Bcells_Human0.98292612
108SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.97982810
109TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.97743921
110MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.97657067
111CREB1_26743006_Chip-Seq_LNCaP_Human0.96514200
112CTCF_27219007_Chip-Seq_ERYTHROID_Human0.96114511
113JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.95896743
114PPAR_26484153_Chip-Seq_NCI-H1993_Human0.94765923
115MITF_21258399_ChIP-Seq_MELANOMA_Human0.94745071
116VDR_24787735_ChIP-Seq_THP-1_Human0.94621571
117* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.94551609
118TP53_23651856_ChIP-Seq_MEFs_Mouse0.94312147
119MAF_26560356_Chip-Seq_TH1_Human0.93791495
120TET1_21451524_ChIP-Seq_MESCs_Mouse0.93098356
121TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.92323425
122RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.91471619
123CDX2_20551321_ChIP-Seq_CACO-2_Human0.91259794
124TP63_22573176_ChIP-Seq_HFKS_Human0.91051843
125STAT6_21828071_ChIP-Seq_BEAS2B_Human0.90906706
126ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.90556248
127PU_27001747_Chip-Seq_BMDM_Mouse0.90067161
128TET1_21490601_ChIP-Seq_MESCs_Mouse0.88310785
129P68_20966046_ChIP-Seq_HELA_Human0.87446565
130BCOR_27268052_Chip-Seq_Bcells_Human0.87196103
131GATA2_19941826_ChIP-Seq_K562_Human0.87064635
132GATA6_25053715_ChIP-Seq_YYC3_Human0.86641949
133PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86064461
134CTNNB1_20460455_ChIP-Seq_HCT116_Human0.85890910
135AHR_22903824_ChIP-Seq_MCF-7_Human0.84466658
136HIF1A_21447827_ChIP-Seq_MCF-7_Human0.84434204

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation6.72315479
2MP0003172_abnormal_lysosome_physiology5.48434705
3MP0005058_abnormal_lysosome_morphology5.08076700
4MP0009278_abnormal_bone_marrow3.65529669
5MP0005409_darkened_coat_color2.86035403
6MP0005174_abnormal_tail_pigmentation2.75822926
7MP0003283_abnormal_digestive_organ2.70995216
8MP0003045_fibrosis2.57255008
9MP0000371_diluted_coat_color2.29052370
10MP0010234_abnormal_vibrissa_follicle2.28930209
11MP0003300_gastrointestinal_ulcer2.26310258
12MP0004510_myositis2.25695022
13MP0005076_abnormal_cell_differentiation2.23069516
14MP0002877_abnormal_melanocyte_morpholog2.19628026
15MP0005451_abnormal_body_composition2.11536416
16MP0003566_abnormal_cell_adhesion2.11043004
17MP0004233_abnormal_muscle_weight2.10825137
18MP0004381_abnormal_hair_follicle2.10491033
19MP0003705_abnormal_hypodermis_morpholog2.06492345
20MP0000015_abnormal_ear_pigmentation2.03045966
21MP0009840_abnormal_foam_cell1.93717981
22MP0003183_abnormal_peptide_metabolism1.86913776
23MP0008260_abnormal_autophagy1.85785252
24MP0005257_abnormal_intraocular_pressure1.70198493
25MP0008961_abnormal_basal_metabolism1.70070018
26MP0003879_abnormal_hair_cell1.64220952
27MP0002796_impaired_skin_barrier1.63132516
28MP0005670_abnormal_white_adipose1.62330876
29MP0001348_abnormal_lacrimal_gland1.50934914
30MP0010307_abnormal_tumor_latency1.50134578
31MP0001958_emphysema1.45655063
32MP0004264_abnormal_extraembryonic_tissu1.44633668
33MP0003329_amyloid_beta_deposits1.43282234
34MP0003191_abnormal_cellular_cholesterol1.42563349
35MP0006082_CNS_inflammation1.41924361
36MP0005083_abnormal_biliary_tract1.41467493
37MP0002933_joint_inflammation1.40544145
38MP0003303_peritoneal_inflammation1.40190316
39MP0005464_abnormal_platelet_physiology1.36756380
40MP0010155_abnormal_intestine_physiology1.30745697
41MP0005025_abnormal_response_to1.29919906
42MP0004859_abnormal_synaptic_plasticity1.29102833
43MP0001545_abnormal_hematopoietic_system1.26098893
44MP0005397_hematopoietic_system_phenotyp1.26098893
45MP0004130_abnormal_muscle_cell1.25858660
46MP0004858_abnormal_nervous_system1.22352918
47MP0002168_other_aberrant_phenotype1.21189618
48MP0003075_altered_response_to1.19306149
49MP0003091_abnormal_cell_migration1.19160326
50MP0005365_abnormal_bile_salt1.16335846
51MP0003436_decreased_susceptibility_to1.16118685
52MP0000013_abnormal_adipose_tissue1.15340776
53MP0008438_abnormal_cutaneous_collagen1.15175398
54MP0002166_altered_tumor_susceptibility1.14510026
55MP0000751_myopathy1.11812892
56MP0005171_absent_coat_pigmentation1.11240481
57MP0005377_hearing/vestibular/ear_phenot1.09616362
58MP0003878_abnormal_ear_physiology1.09616362
59MP0000604_amyloidosis1.09255344
60MP0001533_abnormal_skeleton_physiology1.08979621
61MP0000678_abnormal_parathyroid_gland1.08868321
62MP0003453_abnormal_keratinocyte_physiol1.08474694
63MP0002269_muscular_atrophy1.07854006
64MP0002928_abnormal_bile_duct1.04981864
65MP0005000_abnormal_immune_tolerance1.03307011
66MP0002998_abnormal_bone_remodeling1.01328877
67MP0000858_altered_metastatic_potential1.00696964
68MP0001324_abnormal_eye_pigmentation1.00052146
69MP0004947_skin_inflammation0.98914788
70MP0002419_abnormal_innate_immunity0.98527151
71MP0003690_abnormal_glial_cell0.97896606
72MP0009780_abnormal_chondrocyte_physiolo0.96440892
73MP0005501_abnormal_skin_physiology0.94958174
74MP0002148_abnormal_hypersensitivity_rea0.94877425
75MP0002452_abnormal_antigen_presenting0.93952809
76MP0008874_decreased_physiological_sensi0.93812896
77MP0002909_abnormal_adrenal_gland0.93675087
78MP0001216_abnormal_epidermal_layer0.92764182
79MP0009046_muscle_twitch0.92176514
80MP0002089_abnormal_postnatal_growth/wei0.91529054
81MP0008004_abnormal_stomach_pH0.91160588
82MP0001800_abnormal_humoral_immune0.91152913
83MP0001765_abnormal_ion_homeostasis0.90470782
84MP0002723_abnormal_immune_serum0.90153154
85MP0005423_abnormal_somatic_nervous0.89833202
86MP0010352_gastrointestinal_tract_polyps0.89529352
87MP0005023_abnormal_wound_healing0.89461064
88MP0009931_abnormal_skin_appearance0.88898324
89MP0005666_abnormal_adipose_tissue0.88522633
90MP0003763_abnormal_thymus_physiology0.88170697
91MP0002098_abnormal_vibrissa_morphology0.87869630
92MP0003252_abnormal_bile_duct0.86125030
93MP0005623_abnormal_meninges_morphology0.85104333
94MP0002060_abnormal_skin_morphology0.82509790
95MP0000767_abnormal_smooth_muscle0.82384902
96MP0009115_abnormal_fat_cell0.82296911
97MP0001873_stomach_inflammation0.82055289
98MP0001819_abnormal_immune_cell0.82036169
99MP0010630_abnormal_cardiac_muscle0.81818806
100MP0002075_abnormal_coat/hair_pigmentati0.81575824
101MP0002420_abnormal_adaptive_immunity0.81107712
102MP0000579_abnormal_nail_morphology0.81072361
103MP0005360_urolithiasis0.79265383
104MP0001986_abnormal_taste_sensitivity0.78634428
105MP0002249_abnormal_larynx_morphology0.78235633
106MP0003279_aneurysm0.77733116
107MP0002405_respiratory_system_inflammati0.75444462
108MP0001502_abnormal_circadian_rhythm0.74997335
109MP0003633_abnormal_nervous_system0.74884870
110MP0005166_decreased_susceptibility_to0.74451907
111MP0001845_abnormal_inflammatory_respons0.74170318
112MP0003448_altered_tumor_morphology0.73465366
113MP0005310_abnormal_salivary_gland0.73332746
114MP0004185_abnormal_adipocyte_glucose0.72286500
115MP0002693_abnormal_pancreas_physiology0.71942748
116MP0000685_abnormal_immune_system0.71313159
117MP0000249_abnormal_blood_vessel0.70915456
118MP0003634_abnormal_glial_cell0.70165188
119MP0003890_abnormal_embryonic-extraembry0.69523136
120MP0005387_immune_system_phenotype0.69359385
121MP0001790_abnormal_immune_system0.69359385
122MP0009785_altered_susceptibility_to0.69042970
123MP0002118_abnormal_lipid_homeostasis0.67697079
124MP0000609_abnormal_liver_physiology0.67390163
125MP0002006_tumorigenesis0.66750392
126MP0003828_pulmonary_edema0.66460165
127MP0002139_abnormal_hepatobiliary_system0.65988379
128MP0002078_abnormal_glucose_homeostasis0.64645585
129MP0005167_abnormal_blood-brain_barrier0.64233757
130MP0002971_abnormal_brown_adipose0.63888091
131MP0001849_ear_inflammation0.63590642
132MP0010386_abnormal_urinary_bladder0.62997706
133MP0004087_abnormal_muscle_fiber0.61667371
134MP0000733_abnormal_muscle_development0.60680811
135MP0001186_pigmentation_phenotype0.59896648
136MP0000538_abnormal_urinary_bladder0.59706159
137MP0001835_abnormal_antigen_presentation0.59546347
138MP0005621_abnormal_cell_physiology0.57268100
139MP0000470_abnormal_stomach_morphology0.57091151
140MP0010329_abnormal_lipoprotein_level0.57049530
141MP0002332_abnormal_exercise_endurance0.56862544
142MP0002254_reproductive_system_inflammat0.56356359
143MP0002009_preneoplasia0.55353506
144MP0002135_abnormal_kidney_morphology0.55130023
145MP0005645_abnormal_hypothalamus_physiol0.55003452
146MP0004019_abnormal_vitamin_homeostasis0.54851696
147MP0005375_adipose_tissue_phenotype0.54603086
148MP0000003_abnormal_adipose_tissue0.53812616
149MP0005334_abnormal_fat_pad0.53334268

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of polysaccharide metabolism (HP:0011012)4.57487185
2Abnormality of glycosaminoglycan metabolism (HP:0004371)4.57487185
3Abnormality of mucopolysaccharide metabolism (HP:0011020)4.57487185
4Dysostosis multiplex (HP:0000943)4.46363767
5Mucopolysacchariduria (HP:0008155)4.44325021
6Urinary glycosaminoglycan excretion (HP:0003541)4.44325021
7Cerebral aneurysm (HP:0004944)4.11094878
8Increased cerebral lipofuscin (HP:0011813)4.01662191
9Turricephaly (HP:0000262)3.79894259
10Obstructive sleep apnea (HP:0002870)3.71744146
11Broad face (HP:0000283)3.54304263
12Asymmetric septal hypertrophy (HP:0001670)3.48952204
13J-shaped sella turcica (HP:0002680)3.43133103
14Alopecia of scalp (HP:0002293)3.27420597
15Increased neuronal autofluorescent lipopigment (HP:0002074)3.10839409
16Malnutrition (HP:0004395)3.03447584
17Ulnar bowing (HP:0003031)3.01791624
18Nuclear cataract (HP:0100018)2.86921886
19Pustule (HP:0200039)2.86090558
20Vacuolated lymphocytes (HP:0001922)2.80139889
21Hand muscle atrophy (HP:0009130)2.79048402
22Neurofibrillary tangles (HP:0002185)2.78386166
23Abnormality of glycolipid metabolism (HP:0010969)2.76558969
24Abnormality of liposaccharide metabolism (HP:0010968)2.76558969
25Abnormality of glycosphingolipid metabolism (HP:0004343)2.76558969
26Hemorrhage of the eye (HP:0011885)2.71775240
27Distal upper limb amyotrophy (HP:0007149)2.68814109
28Upper limb amyotrophy (HP:0009129)2.68814109
29Myocardial infarction (HP:0001658)2.65623941
30Urethral obstruction (HP:0000796)2.62602235
31Increased CSF protein (HP:0002922)2.51401159
32Thoracic kyphosis (HP:0002942)2.47518325
33Flat acetabular roof (HP:0003180)2.46695352
34Albinism (HP:0001022)2.44272890
35Axonal loss (HP:0003447)2.39242507
36Macroorchidism (HP:0000053)2.37559416
37Stridor (HP:0010307)2.37352078
38Loss of speech (HP:0002371)2.37100716
39Supranuclear gaze palsy (HP:0000605)2.36147087
40Recurrent abscess formation (HP:0002722)2.35194578
41Global brain atrophy (HP:0002283)2.32935496
42Coarse hair (HP:0002208)2.32849820
43Annular pancreas (HP:0001734)2.32378365
44Long toe (HP:0010511)2.29902011
45Colitis (HP:0002583)2.27767646
46Recurrent bacterial skin infections (HP:0005406)2.27238709
47Cerebral inclusion bodies (HP:0100314)2.25365674
48Bilateral sensorineural hearing impairment (HP:0008619)2.12883450
49Heterotopia (HP:0002282)2.07385362
50Aneurysm (HP:0002617)2.06082128
51Increased connective tissue (HP:0009025)2.04809803
52Abnormality of macrophages (HP:0004311)2.03480252
53Neuronal loss in central nervous system (HP:0002529)2.03233956
54Abnormality of the periventricular white matter (HP:0002518)2.00943286
55Progressive hearing impairment (HP:0001730)2.00689867
56Distal lower limb amyotrophy (HP:0008944)2.00298338
57Progressive sensorineural hearing impairment (HP:0000408)1.99431347
58Deformed sella turcica (HP:0002681)1.99252668
59Generalized hypopigmentation (HP:0007513)1.98277428
60Atrophic scars (HP:0001075)1.97397674
61Frequent falls (HP:0002359)1.97356417
62Pathologic fracture (HP:0002756)1.97244176
63Joint stiffness (HP:0001387)1.97221072
64Bronchomalacia (HP:0002780)1.96330046
65Difficulty climbing stairs (HP:0003551)1.95375282
66Autoimmune thrombocytopenia (HP:0001973)1.94009507
67Interstitial pulmonary disease (HP:0006530)1.91827778
68Ocular albinism (HP:0001107)1.91738315
69Cervical subluxation (HP:0003308)1.91665522
70Easy fatigability (HP:0003388)1.91464586
71Gingivitis (HP:0000230)1.90808481
72Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.89806937
73Abnormality of vision evoked potentials (HP:0000649)1.88790363
74Mildly elevated creatine phosphokinase (HP:0008180)1.87469227
75Onion bulb formation (HP:0003383)1.86615438
76Emphysema (HP:0002097)1.85687106
77Spinal muscular atrophy (HP:0007269)1.83670414
78Intestinal fistula (HP:0100819)1.83568150
79Hypoplastic ischia (HP:0003175)1.82166843
80Increased IgE level (HP:0003212)1.81778953
81Hyperacusis (HP:0010780)1.80170528
82Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.78285099
83Periodontitis (HP:0000704)1.77704966
84Abnormality of the fingertips (HP:0001211)1.77434126
85Thin bony cortex (HP:0002753)1.75824332
86Peripheral demyelination (HP:0011096)1.74260830
87Fragile skin (HP:0001030)1.74245037
88Bowed forearm bones (HP:0003956)1.74238315
89Bowing of the arm (HP:0006488)1.74238315
90Bone pain (HP:0002653)1.73760008
91Retinal atrophy (HP:0001105)1.73705730
92Hypercortisolism (HP:0001578)1.73005633
93Lymphangioma (HP:0100764)1.72306662
94Milia (HP:0001056)1.72121518
95Tetany (HP:0001281)1.71019054
96Eczematoid dermatitis (HP:0000976)1.70605651
97Natal tooth (HP:0000695)1.69950048
98Large for gestational age (HP:0001520)1.69455602
99Lower limb amyotrophy (HP:0007210)1.69375287
100Abdominal distention (HP:0003270)1.68853561
101Tetraparesis (HP:0002273)1.67448343
102Abnormality of the nasal mucosa (HP:0000433)1.66905952
103Absent frontal sinuses (HP:0002688)1.66033266
104Abnormality of alkaline phosphatase activity (HP:0004379)1.64325895
105Protuberant abdomen (HP:0001538)1.63845955
106Clumsiness (HP:0002312)1.63817491
107Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.63308973
108Abnormality of the ischium (HP:0003174)1.62953439
109Apathy (HP:0000741)1.62748274
110Inflammation of the large intestine (HP:0002037)1.61513729
111Abnormal enzyme/coenzyme activity (HP:0012379)1.60625558
112Long palpebral fissure (HP:0000637)1.59961394
113Hemiplegia (HP:0002301)1.59865022
114Polygenic inheritance (HP:0010982)1.59848866
115Increased serum ferritin (HP:0003281)1.58952079
116Ankle clonus (HP:0011448)1.58714788
117Abnormality of proline metabolism (HP:0010907)1.58380674
118Hydroxyprolinuria (HP:0003080)1.58380674
119Distal lower limb muscle weakness (HP:0009053)1.58124130
120Congenital hip dislocation (HP:0001374)1.57978016
121Male infertility (HP:0003251)1.56321049
122Ovoid vertebral bodies (HP:0003300)1.55773450
123Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.55631858
124Premature loss of primary teeth (HP:0006323)1.55223007
125Rapidly progressive (HP:0003678)1.55053313
126Pointed chin (HP:0000307)1.54550864
127Flattened epiphyses (HP:0003071)1.54276723
128Advanced eruption of teeth (HP:0006288)1.54242532
129Status epilepticus (HP:0002133)1.54156278
130Spondylolisthesis (HP:0003302)1.53983566
131Short nail (HP:0001799)1.53559526
132Shallow orbits (HP:0000586)1.52762127
133Diminished motivation (HP:0000745)1.52260369
134Hypertriglyceridemia (HP:0002155)1.52170083
135Systemic lupus erythematosus (HP:0002725)1.51859809
136Upper motor neuron abnormality (HP:0002127)1.51569412
137EMG: neuropathic changes (HP:0003445)1.51557872
138Leiomyosarcoma (HP:0100243)1.51354502
139Uterine leiomyosarcoma (HP:0002891)1.51354502
140Glomerulonephritis (HP:0000099)1.51176114
141Hypoplasia of the odontoid process (HP:0003311)1.51046400
142Hypophosphatemia (HP:0002148)1.50781830
143Recurrent gram-negative bacterial infections (HP:0005420)1.50778465
144Nephritis (HP:0000123)1.50656990
145Segmental peripheral demyelination/remyelination (HP:0003481)1.50425742
146Gastrointestinal inflammation (HP:0004386)1.50368436
147Aortic regurgitation (HP:0001659)1.50216442
148Thick nail (HP:0001805)1.49769949
149Achilles tendon contracture (HP:0001771)1.49145555
150Iris hypopigmentation (HP:0007730)1.49074487
151Abnormality of the thoracic spine (HP:0100711)1.48467781
152Abnormality of the astrocytes (HP:0100707)1.48037741
153Abnormality of the sella turcica (HP:0002679)1.46600962
154Abnormality of the odontoid process (HP:0003310)1.46320233
155Dysmetric saccades (HP:0000641)1.46043308

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK3.71752909
2MST1R2.74410533
3DDR22.73331520
4TRIB32.52467747
5ERN12.45564837
6SIK22.43013050
7TAOK32.36156147
8MAPK152.12046739
9CAMK1D2.03996668
10RIPK12.00310122
11CAMK1G2.00009423
12PDGFRA1.93850562
13TTN1.90321830
14CDK121.86969688
15BMX1.82955411
16SIK11.71401512
17MAP3K61.69315367
18PKN21.69211245
19EEF2K1.65861565
20STK381.54296371
21PTK61.53915011
22FGR1.51612812
23BLK1.48960924
24SMG11.47427035
25MATK1.44457773
26RIPK41.41252084
27CDC42BPA1.38646668
28PTK21.36362402
29PRPF4B1.35674699
30CSK1.32567281
31DYRK1B1.31305494
32TYRO31.25172268
33LATS11.25084163
34DAPK21.22136573
35PRKD21.20249379
36MTOR1.20235418
37MAP3K91.18950028
38SIK31.17528487
39DAPK11.17100388
40MAP3K101.15960375
41PINK11.11305912
42CDK61.11112962
43JAK11.10381174
44TRPM71.09268763
45MAP2K61.05619360
46PRKD31.04472222
47MET1.03008451
48MAP3K131.02350040
49TYK21.01298739
50KIT0.99581632
51MAPKAPK30.98855401
52CAMKK10.98701287
53SGK30.98632438
54MAP3K110.98307508
55MAP3K70.96364763
56INSRR0.94262534
57NME20.94017155
58LMTK20.93226272
59SCYL20.93012033
60PDGFRB0.89704376
61TESK10.87045269
62MAP3K10.86807474
63HIPK20.85775030
64RPS6KL10.84970264
65RPS6KC10.84970264
66TBK10.83442816
67IRAK30.80956634
68MAPK120.79656731
69PRKAA10.76842393
70RPS6KA60.76192505
71GRK60.74167280
72EPHA20.73146287
73MAP3K140.70549060
74JAK20.68815057
75CHUK0.67695845
76PAK60.67416711
77EPHB10.66899146
78MAP4K10.66121779
79WNK10.66098925
80PRKCH0.65032730
81HCK0.64167687
82MARK20.63944498
83TGFBR20.62836856
84JAK30.62718618
85NTRK10.62236253
86YES10.61865809
87PAK40.60819895
88UHMK10.60739507
89EGFR0.60254322
90TAOK20.59482518
91ZAP700.58832277
92IRAK20.58628725
93SGK10.57779851
94CSF1R0.56246214
95RPS6KA20.54880553
96TNK20.54868190
97PDPK10.54188006
98SGK20.53964468
99GSK3A0.53951875
100PIM10.53722544
101IRAK40.52507542
102MAPK70.52461073
103IKBKE0.51632204
104BRD40.51200568
105MAP2K30.51066883
106STK30.50443844
107BTK0.50410843
108MUSK0.49590511
109IKBKB0.49238953
110FES0.49236612
111LATS20.49084976
112ERBB20.48820535
113ALK0.48662618
114FLT30.48545675
115PRKAA20.47919394
116MAP3K30.46558813
117DMPK0.46300671
118PRKG20.46145074
119RET0.45992130
120FGFR40.45056691
121MARK30.44794156
122MAPK110.44726603
123PDK10.43541258
124MAP2K20.43449763
125TAOK10.43150645
126CAMK40.43001245
127PRKD10.41144432
128KSR20.40555406
129PIM20.39502438
130MAPK80.37937691
131ARAF0.37432310
132MAP3K20.36572152
133NTRK30.36055710

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosaminoglycan degradation_Homo sapiens_hsa005312.82156246
2Lysosome_Homo sapiens_hsa041422.41375162
3Fatty acid biosynthesis_Homo sapiens_hsa000611.86700412
4Type II diabetes mellitus_Homo sapiens_hsa049301.84264826
5Other glycan degradation_Homo sapiens_hsa005111.77520099
6mTOR signaling pathway_Homo sapiens_hsa041501.75248183
7Lysine degradation_Homo sapiens_hsa003101.73758341
8Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.63094363
9Carbohydrate digestion and absorption_Homo sapiens_hsa049731.49365408
10Longevity regulating pathway - mammal_Homo sapiens_hsa042111.34015042
11Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.25677579
12Synaptic vesicle cycle_Homo sapiens_hsa047211.25594017
13Chronic myeloid leukemia_Homo sapiens_hsa052201.23200462
14Osteoclast differentiation_Homo sapiens_hsa043801.22503930
15Phosphatidylinositol signaling system_Homo sapiens_hsa040701.19198793
16Notch signaling pathway_Homo sapiens_hsa043301.17326988
17Maturity onset diabetes of the young_Homo sapiens_hsa049501.14093056
18Insulin resistance_Homo sapiens_hsa049311.13923033
19Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.10668197
20Caffeine metabolism_Homo sapiens_hsa002321.09116149
21B cell receptor signaling pathway_Homo sapiens_hsa046621.08494730
22Hepatitis C_Homo sapiens_hsa051601.05524403
23Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.05446046
24Collecting duct acid secretion_Homo sapiens_hsa049661.03674592
25ABC transporters_Homo sapiens_hsa020101.03575199
26Staphylococcus aureus infection_Homo sapiens_hsa051501.02116458
27Tuberculosis_Homo sapiens_hsa051521.01120563
28Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.00389832
29Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.98215557
30Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.97524139
31Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.97179191
32Bladder cancer_Homo sapiens_hsa052190.95913963
33Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.95590966
34Dorso-ventral axis formation_Homo sapiens_hsa043200.94912608
35Adherens junction_Homo sapiens_hsa045200.93230005
36Insulin signaling pathway_Homo sapiens_hsa049100.91947633
37Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.91775496
38Insulin secretion_Homo sapiens_hsa049110.91181718
39Toll-like receptor signaling pathway_Homo sapiens_hsa046200.90067198
40Leukocyte transendothelial migration_Homo sapiens_hsa046700.89034507
41Cyanoamino acid metabolism_Homo sapiens_hsa004600.88934142
42Proteoglycans in cancer_Homo sapiens_hsa052050.88274840
43Acute myeloid leukemia_Homo sapiens_hsa052210.86492861
44Fructose and mannose metabolism_Homo sapiens_hsa000510.86086041
45Sphingolipid metabolism_Homo sapiens_hsa006000.85399847
46Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.84918735
47Glycerophospholipid metabolism_Homo sapiens_hsa005640.84895046
48Phagosome_Homo sapiens_hsa041450.84771830
49T cell receptor signaling pathway_Homo sapiens_hsa046600.84279291
50NF-kappa B signaling pathway_Homo sapiens_hsa040640.83990722
51VEGF signaling pathway_Homo sapiens_hsa043700.83971935
52RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.83863936
53Pertussis_Homo sapiens_hsa051330.83346193
54Bile secretion_Homo sapiens_hsa049760.80632201
55Estrogen signaling pathway_Homo sapiens_hsa049150.80286751
56Renal cell carcinoma_Homo sapiens_hsa052110.79997455
57Amoebiasis_Homo sapiens_hsa051460.79427741
58Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.79309914
59Focal adhesion_Homo sapiens_hsa045100.78965510
60Long-term potentiation_Homo sapiens_hsa047200.78874591
61Inositol phosphate metabolism_Homo sapiens_hsa005620.78752554
62Glioma_Homo sapiens_hsa052140.78508395
63Leishmaniasis_Homo sapiens_hsa051400.78368775
64Sphingolipid signaling pathway_Homo sapiens_hsa040710.78107490
65Prion diseases_Homo sapiens_hsa050200.77421104
66Fatty acid metabolism_Homo sapiens_hsa012120.76632053
67Platelet activation_Homo sapiens_hsa046110.76199010
68Adipocytokine signaling pathway_Homo sapiens_hsa049200.76164888
69Regulation of actin cytoskeleton_Homo sapiens_hsa048100.75019402
70Galactose metabolism_Homo sapiens_hsa000520.74227594
71Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.74219611
72Neurotrophin signaling pathway_Homo sapiens_hsa047220.74014983
73Endometrial cancer_Homo sapiens_hsa052130.72304269
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.71308258
75Choline metabolism in cancer_Homo sapiens_hsa052310.71166434
76AMPK signaling pathway_Homo sapiens_hsa041520.71090549
77Glucagon signaling pathway_Homo sapiens_hsa049220.70914044
78Arginine biosynthesis_Homo sapiens_hsa002200.70499290
79Glycerolipid metabolism_Homo sapiens_hsa005610.70336586
80Prolactin signaling pathway_Homo sapiens_hsa049170.70294469
81Pentose and glucuronate interconversions_Homo sapiens_hsa000400.69511189
82Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.69312609
83AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.68433823
84Central carbon metabolism in cancer_Homo sapiens_hsa052300.67839241
85Mineral absorption_Homo sapiens_hsa049780.67631339
86MAPK signaling pathway_Homo sapiens_hsa040100.67040965
87Pancreatic cancer_Homo sapiens_hsa052120.66660441
88Endocytosis_Homo sapiens_hsa041440.66042651
89Apoptosis_Homo sapiens_hsa042100.64836902
90Toxoplasmosis_Homo sapiens_hsa051450.64375279
91Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.64320652
92Circadian rhythm_Homo sapiens_hsa047100.64313776
93Shigellosis_Homo sapiens_hsa051310.64002712
94GnRH signaling pathway_Homo sapiens_hsa049120.63693191
95Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.63618226
96Small cell lung cancer_Homo sapiens_hsa052220.63180190
97ErbB signaling pathway_Homo sapiens_hsa040120.62203518
98Starch and sucrose metabolism_Homo sapiens_hsa005000.61198349
99Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61098747
100Hepatitis B_Homo sapiens_hsa051610.60653782
101ECM-receptor interaction_Homo sapiens_hsa045120.60396753
102Aldosterone synthesis and secretion_Homo sapiens_hsa049250.59962126
103Non-small cell lung cancer_Homo sapiens_hsa052230.59079290
104Malaria_Homo sapiens_hsa051440.58957019
105Pancreatic secretion_Homo sapiens_hsa049720.58835178
106Gastric acid secretion_Homo sapiens_hsa049710.58220882
107Dilated cardiomyopathy_Homo sapiens_hsa054140.57414964
108Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57329416
109TNF signaling pathway_Homo sapiens_hsa046680.57235285
110Oxytocin signaling pathway_Homo sapiens_hsa049210.57033205
111Vascular smooth muscle contraction_Homo sapiens_hsa042700.56977061
112Cholinergic synapse_Homo sapiens_hsa047250.54956069
113Rap1 signaling pathway_Homo sapiens_hsa040150.54479190
114Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.53664700
115Phospholipase D signaling pathway_Homo sapiens_hsa040720.53235577
116NOD-like receptor signaling pathway_Homo sapiens_hsa046210.53068509
117Salmonella infection_Homo sapiens_hsa051320.51826726
118Influenza A_Homo sapiens_hsa051640.51739466
119Legionellosis_Homo sapiens_hsa051340.50576414
120Salivary secretion_Homo sapiens_hsa049700.50406001
121Chemokine signaling pathway_Homo sapiens_hsa040620.50328036
122Thyroid hormone synthesis_Homo sapiens_hsa049180.49826655
123Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.49376381
124Ovarian steroidogenesis_Homo sapiens_hsa049130.49284081
125Axon guidance_Homo sapiens_hsa043600.49274595
126HIF-1 signaling pathway_Homo sapiens_hsa040660.48277948
127Vibrio cholerae infection_Homo sapiens_hsa051100.47827124

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