MROH2B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.92878801
2piRNA metabolic process (GO:0034587)9.67815533
3spermatid development (GO:0007286)9.42036294
4motile cilium assembly (GO:0044458)9.29661939
5reproduction (GO:0000003)9.06414673
6male meiosis (GO:0007140)8.63387261
7cilium movement (GO:0003341)8.55140730
8regulation of cilium movement (GO:0003352)8.53516712
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.24247827
10synaptonemal complex organization (GO:0070193)8.09390608
11synaptonemal complex assembly (GO:0007130)7.73647838
12single fertilization (GO:0007338)7.47092527
13sperm capacitation (GO:0048240)7.11724807
14establishment of protein localization to Golgi (GO:0072600)7.02902379
15protein targeting to Golgi (GO:0000042)6.76181677
16phosphatidylethanolamine biosynthetic process (GO:0006646)6.63182661
17negative regulation of inclusion body assembly (GO:0090084)6.47658502
18fertilization (GO:0009566)6.46233468
19rRNA methylation (GO:0031167)6.27766395
20retrograde transport, vesicle recycling within Golgi (GO:0000301)6.26560091
21spermatogenesis (GO:0007283)6.20406656
22male gamete generation (GO:0048232)6.18166627
23phosphatidylethanolamine metabolic process (GO:0046337)6.16712593
24DNA methylation involved in gamete generation (GO:0043046)6.09893366
25male meiosis I (GO:0007141)6.00619032
26response to pheromone (GO:0019236)5.82216256
27gamete generation (GO:0007276)5.68707592
28organic cation transport (GO:0015695)5.64404302
29ventricular system development (GO:0021591)5.62597866
30microtubule depolymerization (GO:0007019)5.43234271
31cellular process involved in reproduction in multicellular organism (GO:0022412)5.42325410
32germ cell development (GO:0007281)5.41249747
33chromosome organization involved in meiosis (GO:0070192)5.39918997
34regulation of inclusion body assembly (GO:0090083)5.30899142
35rRNA modification (GO:0000154)5.22759689
36cellular ketone body metabolic process (GO:0046950)5.08272764
37meiotic nuclear division (GO:0007126)5.07860350
38regulation of microtubule-based movement (GO:0060632)5.05373769
39seminiferous tubule development (GO:0072520)4.97972486
40calcium ion-dependent exocytosis (GO:0017156)4.96303295
41protein localization to Golgi apparatus (GO:0034067)4.85738815
42meiosis I (GO:0007127)4.85514977
43cell recognition (GO:0008037)4.83131826
44microtubule severing (GO:0051013)4.79152824
45sexual reproduction (GO:0019953)4.52556150
46left/right pattern formation (GO:0060972)4.48676647
47multicellular organismal reproductive process (GO:0048609)4.47762318
48ketone body metabolic process (GO:1902224)4.46538574
49meiotic cell cycle (GO:0051321)4.35728168
50protein localization to cilium (GO:0061512)4.26505841
51positive regulation of Rab GTPase activity (GO:0032851)4.21913543
52regulation of Rab GTPase activity (GO:0032313)4.21913543
53genitalia morphogenesis (GO:0035112)4.02914954
54monoubiquitinated protein deubiquitination (GO:0035520)4.01463585
55protein polyglutamylation (GO:0018095)3.94414938
56spermatid nucleus differentiation (GO:0007289)3.91906677
57positive regulation of histone deacetylation (GO:0031065)3.81421705
58glycerol ether metabolic process (GO:0006662)3.77552611
59RNA destabilization (GO:0050779)3.69866616
60insulin-like growth factor receptor signaling pathway (GO:0048009)3.69530327
61chromosome condensation (GO:0030261)3.68000836
62glomerular visceral epithelial cell development (GO:0072015)3.67386493
63chaperone-mediated protein complex assembly (GO:0051131)3.66933531
64gene silencing by RNA (GO:0031047)3.60955830
65regulation of phosphoprotein phosphatase activity (GO:0043666)3.60794275
66multicellular organismal development (GO:0007275)3.60705721
67DNA packaging (GO:0006323)3.60658720
68multicellular organismal movement (GO:0050879)3.59140003
69musculoskeletal movement (GO:0050881)3.59140003
70intraciliary transport (GO:0042073)3.56699996
71response to misfolded protein (GO:0051788)3.53574813
72ether metabolic process (GO:0018904)3.48528004
73negative regulation of organelle assembly (GO:1902116)3.46943462
74regulation of transcription involved in cell fate commitment (GO:0060850)3.42591862
75glomerular epithelial cell development (GO:0072310)3.41948203
76amino-acid betaine transport (GO:0015838)3.35789409
77carnitine transport (GO:0015879)3.35789409
78axoneme assembly (GO:0035082)3.34447422
79response to acidic pH (GO:0010447)3.31352813
80carnitine transmembrane transport (GO:1902603)3.28819360
81meiotic cell cycle process (GO:1903046)3.28562075
82microtubule-based movement (GO:0007018)3.28442655
83regulation of spindle checkpoint (GO:0090231)3.24376207
84synapsis (GO:0007129)3.23094468
85protein refolding (GO:0042026)3.22624531
86protein K48-linked deubiquitination (GO:0071108)3.16748235
87regulation of somitogenesis (GO:0014807)3.15692943
88detection of chemical stimulus involved in sensory perception of smell (GO:0050911)3.14687166
89regulation of centriole replication (GO:0046599)3.11926068
90nuclear pore complex assembly (GO:0051292)3.11596885
91cilium organization (GO:0044782)3.09731466
92polyamine biosynthetic process (GO:0006596)3.08731511
93regulation of meiosis I (GO:0060631)3.04865323
94lactate metabolic process (GO:0006089)3.04193157
95microtubule nucleation (GO:0007020)2.96515712
96indolalkylamine catabolic process (GO:0046218)2.93676436
97tryptophan catabolic process (GO:0006569)2.93676436
98indole-containing compound catabolic process (GO:0042436)2.93676436
99mitotic sister chromatid cohesion (GO:0007064)2.93591066
100cilium assembly (GO:0042384)2.93152797
101alditol metabolic process (GO:0019400)2.93112008
102cellular response to pH (GO:0071467)2.91297982
103negative regulation of Rho protein signal transduction (GO:0035024)2.90964983
104chromatin silencing (GO:0006342)2.90325219
105nucleus organization (GO:0006997)2.89296378
106regulation of interleukin-13 production (GO:0032656)2.85755216
107polyol catabolic process (GO:0046174)2.85693913
108cellular component assembly involved in morphogenesis (GO:0010927)2.84528603
109cilium morphogenesis (GO:0060271)2.83991958
110nucleoside diphosphate phosphorylation (GO:0006165)2.83390677
111glycolytic process (GO:0006096)2.82928684
112G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.81363687
113homeostasis of number of cells within a tissue (GO:0048873)2.79952118
114positive regulation of protein deacetylation (GO:0090312)2.79758827
115peptidyl-glutamic acid modification (GO:0018200)2.78489926
116microtubule polymerization or depolymerization (GO:0031109)2.78432582
117peptide catabolic process (GO:0043171)2.77428855
118single strand break repair (GO:0000012)2.75896544
119NAD biosynthetic process (GO:0009435)2.75824970
120primary amino compound metabolic process (GO:1901160)2.74659245
121intra-Golgi vesicle-mediated transport (GO:0006891)2.74553281
122centriole assembly (GO:0098534)2.72573871
123cellular biogenic amine biosynthetic process (GO:0042401)2.71485234
124centriole replication (GO:0007099)2.71341652
125centrosome duplication (GO:0051298)2.70139497
126protein K11-linked deubiquitination (GO:0035871)2.68300656
127gene silencing (GO:0016458)2.67528148
128coenzyme catabolic process (GO:0009109)2.64380658
129membrane protein intracellular domain proteolysis (GO:0031293)2.64075335
130regulation of protein polyubiquitination (GO:1902914)2.59013960
131sequestering of actin monomers (GO:0042989)2.53739060
132RNA localization (GO:0006403)2.51273246
133glycerol metabolic process (GO:0006071)2.51075776
134interferon-gamma secretion (GO:0072643)2.50604492
135regulation of cilium assembly (GO:1902017)2.46291123
136cilium or flagellum-dependent cell motility (GO:0001539)13.8217785
137fusion of sperm to egg plasma membrane (GO:0007342)13.3209822
138sperm motility (GO:0030317)12.8541923
139sperm-egg recognition (GO:0035036)11.2095981
140acrosome reaction (GO:0007340)11.0487213
141acrosome assembly (GO:0001675)11.0113127
142multicellular organism reproduction (GO:0032504)10.9536447
143axonemal dynein complex assembly (GO:0070286)10.6111184
144cell wall macromolecule metabolic process (GO:0044036)10.3672795
145cell wall macromolecule catabolic process (GO:0016998)10.3672795
146binding of sperm to zona pellucida (GO:0007339)10.2148207
147plasma membrane fusion (GO:0045026)10.1383864
148cell-cell recognition (GO:0009988)10.0267337

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.21619552
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.53041973
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.30781263
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.17998822
5TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.07147341
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.94512996
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.59195197
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.58216468
9CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.30755079
10CTBP1_25329375_ChIP-Seq_LNCAP_Human2.26361107
11MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.19643044
12GBX2_23144817_ChIP-Seq_PC3_Human2.15907863
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.15468285
14STAT6_21828071_ChIP-Seq_BEAS2B_Human2.15447721
15VDR_22108803_ChIP-Seq_LS180_Human2.08824617
16DROSHA_22980978_ChIP-Seq_HELA_Human2.05544552
17ER_23166858_ChIP-Seq_MCF-7_Human2.05179045
18EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.04626103
19IGF1R_20145208_ChIP-Seq_DFB_Human2.04449962
20GATA1_26923725_Chip-Seq_HPCs_Mouse2.04025620
21ZNF274_21170338_ChIP-Seq_K562_Hela2.03742626
22FLI1_27457419_Chip-Seq_LIVER_Mouse2.01707637
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse10.8598307
24VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.98746885
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.92360374
26UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.83614282
27ELK4_26923725_Chip-Seq_MESODERM_Mouse1.82665563
28BP1_19119308_ChIP-ChIP_Hs578T_Human1.78140050
29PCGF2_27294783_Chip-Seq_ESCs_Mouse1.77126051
30ARNT_22903824_ChIP-Seq_MCF-7_Human1.66852090
31TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.65442436
32FUS_26573619_Chip-Seq_HEK293_Human1.60846633
33STAT1_17558387_ChIP-Seq_HELA_Human1.59889895
34FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.59505283
35GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58509491
36WDR5_24793694_ChIP-Seq_LNCAP_Human1.58316448
37SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.58039617
38NANOG_20526341_ChIP-Seq_ESCs_Human1.57277915
39KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.56580186
40ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.54722993
41RAC3_21632823_ChIP-Seq_H3396_Human1.53495433
42EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.52689224
43STAT3_23295773_ChIP-Seq_U87_Human1.51154269
44P300_19829295_ChIP-Seq_ESCs_Human1.50741239
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.50072607
46CBP_20019798_ChIP-Seq_JUKART_Human1.50072607
47GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.48717983
48RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.47334345
49AUTS2_25519132_ChIP-Seq_293T-REX_Human1.47058216
50SMAD3_21741376_ChIP-Seq_EPCs_Human1.46682283
51SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.45184549
52SMAD4_21799915_ChIP-Seq_A2780_Human1.45015559
53MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.41568458
54ERA_21632823_ChIP-Seq_H3396_Human1.41073122
55ETV2_25802403_ChIP-Seq_MESCs_Mouse1.40371892
56AR_25329375_ChIP-Seq_VCAP_Human1.40092652
57KAP1_22055183_ChIP-Seq_ESCs_Mouse1.39800154
58SOX2_22085726_ChIP-Seq_NPCs_Mouse1.39772969
59TAL1_26923725_Chip-Seq_HPCs_Mouse1.37704809
60RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.37106299
61TAF2_19829295_ChIP-Seq_ESCs_Human1.36157592
62PCGF2_27294783_Chip-Seq_NPCs_Mouse1.35382817
63AR_21572438_ChIP-Seq_LNCaP_Human1.34558986
64OCT4_20526341_ChIP-Seq_ESCs_Human1.34176703
65GATA3_21867929_ChIP-Seq_CD8_Mouse1.33770599
66KLF5_20875108_ChIP-Seq_MESCs_Mouse1.33481739
67NFE2_27457419_Chip-Seq_LIVER_Mouse1.33415969
68KDM2B_26808549_Chip-Seq_REH_Human1.32483588
69NANOG_19829295_ChIP-Seq_ESCs_Human1.30652147
70SOX2_19829295_ChIP-Seq_ESCs_Human1.30652147
71MYC_19829295_ChIP-Seq_ESCs_Human1.28758372
72TP53_18474530_ChIP-ChIP_U2OS_Human1.28389656
73AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26182887
74RBPJ_21746931_ChIP-Seq_IB4_Human1.24419852
75LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.23825921
76TOP2B_26459242_ChIP-Seq_MCF-7_Human1.23417070
77CEBPB_22108803_ChIP-Seq_LS180_Human1.23055017
78SMAD3_21741376_ChIP-Seq_ESCs_Human1.22602368
79FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.21898318
80RUNX2_22187159_ChIP-Seq_PCA_Human1.21585154
81CBX2_27304074_Chip-Seq_ESCs_Mouse1.20587858
82REST_21632747_ChIP-Seq_MESCs_Mouse1.20494416
83SUZ12_27294783_Chip-Seq_NPCs_Mouse1.20077394
84SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.19966419
85PRDM14_20953172_ChIP-Seq_ESCs_Human1.19433156
86JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.19413905
87TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19251824
88TCF4_23295773_ChIP-Seq_U87_Human1.19191722
89TBL1_22424771_ChIP-Seq_293T_Human1.18882839
90FLI1_21867929_ChIP-Seq_TH2_Mouse1.18811482
91P53_21459846_ChIP-Seq_SAOS-2_Human1.18559984
92ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.18005865
93CBX2_22325352_ChIP-Seq_293T-Rex_Human1.17867735
94SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.17544261
95ETV1_20927104_ChIP-Seq_GIST48_Human1.16684013
96TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.16171535
97SMAD4_21741376_ChIP-Seq_HESCs_Human1.15738384
98MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.15731869
99GATA3_21867929_ChIP-Seq_TH1_Mouse1.15532877
100HNFA_21074721_ChIP-Seq_CACO-2_Human1.15101754
101OCT1_27270436_Chip-Seq_PROSTATE_Human1.14468691
102PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.13380926
103CJUN_26792858_Chip-Seq_BT549_Human1.11355365
104RUNX1_26923725_Chip-Seq_HPCs_Mouse1.11175245
105POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10979626
106TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10979626
107SMRT_27268052_Chip-Seq_Bcells_Human1.10949783
108PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10524727
109CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.10423508
110GF1_26923725_Chip-Seq_HPCs_Mouse1.10215676
111NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09364068
112RAD21_21589869_ChIP-Seq_MESCs_Mouse1.07735528
113CTCF_27219007_Chip-Seq_Bcells_Human1.07453178
114PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.07443474
115CRX_20693478_ChIP-Seq_RETINA_Mouse1.06923461
116CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06845447
117AHR_22903824_ChIP-Seq_MCF-7_Human1.04745915
118SMC4_20622854_ChIP-Seq_HELA_Human1.04742044
119NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.04619466
120CTBP2_25329375_ChIP-Seq_LNCAP_Human1.04296880
121GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.03757808
122ERG_20517297_ChIP-Seq_VCAP_Human1.03613629
123CTCF_20526341_ChIP-Seq_ESCs_Human1.03056895
124CDX2_22108803_ChIP-Seq_LS180_Human1.02811760
125PHF8_20622853_ChIP-Seq_HELA_Human1.02164231
126NANOG_18555785_Chip-Seq_ESCs_Mouse1.01839222
127BCAT_22108803_ChIP-Seq_LS180_Human1.01787562
128GATA3_21878914_ChIP-Seq_MCF-7_Human1.01356558
129TDRD3_21172665_ChIP-Seq_MCF-7_Human0.99921632
130FOXA1_21572438_ChIP-Seq_LNCaP_Human0.99907344
131TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99890459
132TCF4_22108803_ChIP-Seq_LS180_Human0.99680086
133JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99649368
134OCT4_18555785_Chip-Seq_ESCs_Mouse0.99552459
135TP63_22573176_ChIP-Seq_HFKS_Human0.99477012
136EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.99425286
137BCL6_27268052_Chip-Seq_Bcells_Human0.99192571
138PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.99093245
139PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.99049112
140CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.98569855
141IKZF1_21737484_ChIP-ChIP_HCT116_Human0.98531901
142FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97959317
143SPI1_26923725_Chip-Seq_HPCs_Mouse0.97886388
144EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.97114645
145RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.95902090
146CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95570160
147SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95156086
148CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.94794075
149YY1_22570637_ChIP-Seq_MALME-3M_Human0.94680718
150OCT4_21477851_ChIP-Seq_ESCs_Mouse0.93937807
151RNF2_27304074_Chip-Seq_NSC_Mouse0.93863801
152ESET_19884257_ChIP-Seq_ESCs_Mouse0.93489773
153EZH2_27294783_Chip-Seq_NPCs_Mouse0.93031052
154P53_22387025_ChIP-Seq_ESCs_Mouse0.92971251
155MYC_27129775_Chip-Seq_CORNEA_Mouse0.92015815
156MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91667305
157RXRA_24833708_ChIP-Seq_LIVER_Mouse0.90740269
158EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.90552674
159RARA_24833708_ChIP-Seq_LIVER_Mouse0.90147425
160KLF4_18555785_Chip-Seq_ESCs_Mouse0.89771226
161PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89128056
162SOX2_21211035_ChIP-Seq_LN229_Human0.88825003
163P300_18555785_Chip-Seq_ESCs_Mouse0.88686053
164ESRRB_18555785_Chip-Seq_ESCs_Mouse0.87570793
165RBPJ_22232070_ChIP-Seq_NCS_Mouse0.85892849
166CMYC_18555785_Chip-Seq_ESCs_Mouse0.85617910
167PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.85031036
168TAF15_26573619_Chip-Seq_HEK293_Human0.84795063
169ELF1_20517297_ChIP-Seq_JURKAT_Human0.84423666
170FLI1_21867929_ChIP-Seq_CD8_Mouse0.84160775
171NFYB_21822215_ChIP-Seq_K562_Human0.84137370
172LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.83917708
173SMAD4_21741376_ChIP-Seq_EPCs_Human0.83564483
174EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.83334330
175GATA1_19941827_ChIP-Seq_MEL86_Mouse0.83242933

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.05265677
2MP0001929_abnormal_gametogenesis5.55466982
3MP0008877_abnormal_DNA_methylation4.97052523
4MP0002210_abnormal_sex_determination3.73766811
5MP0002161_abnormal_fertility/fecundity3.29849159
6MP0002653_abnormal_ependyma_morphology3.22192975
7MP0001145_abnormal_male_reproductive3.15355833
8MP0005083_abnormal_biliary_tract3.05666992
9MP0000653_abnormal_sex_gland2.74348511
10MP0005670_abnormal_white_adipose2.19379392
11MP0002160_abnormal_reproductive_system2.10397797
12MP0005623_abnormal_meninges_morphology2.09903102
13MP0001485_abnormal_pinna_reflex2.06117614
14MP0005410_abnormal_fertilization15.6315199
15MP0001348_abnormal_lacrimal_gland1.82993138
16MP0005310_abnormal_salivary_gland1.75350905
17MP0005167_abnormal_blood-brain_barrier1.67152022
18MP0003718_maternal_effect1.67131593
19MP0003646_muscle_fatigue1.67022828
20MP0001486_abnormal_startle_reflex1.60978809
21MP0002138_abnormal_hepatobiliary_system1.58309270
22MP0009053_abnormal_anal_canal1.56703100
23MP0005423_abnormal_somatic_nervous1.56354821
24MP0001501_abnormal_sleep_pattern1.55996907
25MP0005379_endocrine/exocrine_gland_phen1.48938543
26MP0003252_abnormal_bile_duct1.48924786
27MP0005085_abnormal_gallbladder_physiolo1.44679969
28MP0002282_abnormal_trachea_morphology1.43453992
29MP0001968_abnormal_touch/_nociception1.38172400
30MP0001963_abnormal_hearing_physiology1.32837795
31MP0002735_abnormal_chemical_nociception1.25907056
32MP0004233_abnormal_muscle_weight1.23886636
33MP0008057_abnormal_DNA_replication1.23540906
34MP0005365_abnormal_bile_salt1.23414287
35MP0003195_calcinosis1.22996104
36MP0002132_abnormal_respiratory_system1.15199590
37MP0004043_abnormal_pH_regulation1.11415468
38MP0008058_abnormal_DNA_repair1.10596039
39MP0009046_muscle_twitch1.07342743
40MP0005389_reproductive_system_phenotype1.07179947
41MP0010329_abnormal_lipoprotein_level1.05234682
42MP0005647_abnormal_sex_gland1.04595062
43MP0003183_abnormal_peptide_metabolism1.03578533
44MP0001765_abnormal_ion_homeostasis1.02672100
45MP0000026_abnormal_inner_ear1.02117565
46MP0008995_early_reproductive_senescence1.01871156
47MP0001984_abnormal_olfaction1.01498283
48MP0002067_abnormal_sensory_capabilities0.98880510
49MP0005451_abnormal_body_composition0.97785340
50MP0010094_abnormal_chromosome_stability0.97405339
51MP0008872_abnormal_physiological_respon0.97076625
52MP0002272_abnormal_nervous_system0.96492132
53MP0000538_abnormal_urinary_bladder0.91324022
54MP0010386_abnormal_urinary_bladder0.90275490
55MP0005395_other_phenotype0.89374479
56MP0002127_abnormal_cardiovascular_syste0.86347808
57MP0001905_abnormal_dopamine_level0.86256869
58MP0009745_abnormal_behavioral_response0.85969573
59MP0000003_abnormal_adipose_tissue0.85445437
60MP0000230_abnormal_systemic_arterial0.83978064
61MP0010368_abnormal_lymphatic_system0.80274379
62MP0003011_delayed_dark_adaptation0.78757821
63MP0003878_abnormal_ear_physiology0.78568957
64MP0005377_hearing/vestibular/ear_phenot0.78568957
65MP0000955_abnormal_spinal_cord0.77533541
66MP0000569_abnormal_digit_pigmentation0.76245206
67MP0005367_renal/urinary_system_phenotyp0.75545280
68MP0000516_abnormal_urinary_system0.75545280
69MP0002572_abnormal_emotion/affect_behav0.72607219
70MP0001879_abnormal_lymphatic_vessel0.71829724
71MP0000678_abnormal_parathyroid_gland0.71492111
72MP0003950_abnormal_plasma_membrane0.69985167
73MP0008007_abnormal_cellular_replicative0.69754353
74MP0003115_abnormal_respiratory_system0.69547653
75MP0001970_abnormal_pain_threshold0.69241281
76MP0003786_premature_aging0.68020263
77MP0002733_abnormal_thermal_nociception0.67766840
78MP0002557_abnormal_social/conspecific_i0.64809937
79MP0008569_lethality_at_weaning0.64657628
80MP0004085_abnormal_heartbeat0.64036259
81MP0000358_abnormal_cell_content/0.63744383
82MP0009643_abnormal_urine_homeostasis0.63255360
83MP0003959_abnormal_lean_body0.63114584
84MP0005266_abnormal_metabolism0.62601902
85MP0004484_altered_response_of0.61637478
86MP0006276_abnormal_autonomic_nervous0.61563231
87MP0001756_abnormal_urination0.58792187
88MP0000249_abnormal_blood_vessel0.56877959
89MP0003699_abnormal_female_reproductive0.55732511
90MP0009278_abnormal_bone_marrow0.54802434
91MP0005397_hematopoietic_system_phenotyp0.54774054
92MP0001545_abnormal_hematopoietic_system0.54774054
93MP0003880_abnormal_central_pattern0.54098580
94MP0003136_yellow_coat_color0.53051576
95MP0003111_abnormal_nucleus_morphology0.52731635
96MP0005636_abnormal_mineral_homeostasis0.52248621
97MP0001440_abnormal_grooming_behavior0.51867162
98MP0002822_catalepsy0.51475703
99MP0005666_abnormal_adipose_tissue0.51329122
100MP0002928_abnormal_bile_duct0.51083003
101MP0002234_abnormal_pharynx_morphology0.50549096
102MP0003329_amyloid_beta_deposits0.49550392
103MP0002064_seizures0.48851706
104MP0004859_abnormal_synaptic_plasticity0.48336606
105MP0002136_abnormal_kidney_physiology0.47711598
106MP0008004_abnormal_stomach_pH0.47189727
107MP0001293_anophthalmia0.46955734
108MP0001324_abnormal_eye_pigmentation0.43956015
109MP0004036_abnormal_muscle_relaxation0.42096312
110MP0004808_abnormal_hematopoietic_stem0.40216329
111MP0001119_abnormal_female_reproductive0.39772211
112MP0002269_muscular_atrophy0.38229121
113MP0001730_embryonic_growth_arrest0.37340549
114MP0010307_abnormal_tumor_latency0.37313991
115MP0005253_abnormal_eye_physiology0.36242834
116MP0004134_abnormal_chest_morphology0.35016919
117MP0005551_abnormal_eye_electrophysiolog0.34011381
118MP0001764_abnormal_homeostasis0.33647974
119MP0002971_abnormal_brown_adipose0.33592852
120MP0005391_vision/eye_phenotype0.33413420
121MP0006036_abnormal_mitochondrial_physio0.33344047
122MP0009115_abnormal_fat_cell0.32254016
123MP0001661_extended_life_span0.30818122
124MP0001727_abnormal_embryo_implantation0.30522340
125MP0003879_abnormal_hair_cell0.29349146
126MP0008961_abnormal_basal_metabolism0.28231036
127MP0002102_abnormal_ear_morphology0.28100637
128MP0003861_abnormal_nervous_system0.27982415
129MP0000534_abnormal_ureter_morphology0.26569858
130MP0003045_fibrosis0.25810243
131MP0004811_abnormal_neuron_physiology0.25765330
132MP0000313_abnormal_cell_death0.25749825
133MP0000751_myopathy0.25231539
134MP0002152_abnormal_brain_morphology0.24495964
135MP0004019_abnormal_vitamin_homeostasis0.24021662
136MP0003633_abnormal_nervous_system0.23945046
137MP0003077_abnormal_cell_cycle0.23699809
138MP0003942_abnormal_urinary_system0.23629085
139MP0002092_abnormal_eye_morphology0.23474327
140MP0002084_abnormal_developmental_patter0.23353359
141MP0000604_amyloidosis0.21976914
142MP0004133_heterotaxia0.20748223
143MP0002295_abnormal_pulmonary_circulatio0.19983515
144MP0003631_nervous_system_phenotype0.19198571
145MP0006035_abnormal_mitochondrial_morpho0.18466470
146MP0003936_abnormal_reproductive_system0.17587610
147MP0001851_eye_inflammation0.16855113
148MP0003948_abnormal_gas_homeostasis0.16549307
149MP0002736_abnormal_nociception_after0.16090112
150MP0001697_abnormal_embryo_size0.15919338
151MP0003787_abnormal_imprinting0.15741240
152MP0001672_abnormal_embryogenesis/_devel0.15697516
153MP0005380_embryogenesis_phenotype0.15697516
154MP0002169_no_abnormal_phenotype0.15667990
155MP0004742_abnormal_vestibular_system0.15489706
156MP0002873_normal_phenotype0.15430105
157MP0002229_neurodegeneration0.15429811
158MP0004270_analgesia0.15225867
159MP0001986_abnormal_taste_sensitivity0.15130730
160MP0000427_abnormal_hair_cycle0.14890511
161MP0002405_respiratory_system_inflammati0.14130476
162MP0005375_adipose_tissue_phenotype0.13592128
163MP0002108_abnormal_muscle_morphology0.13474019

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.23670393
2Abnormal respiratory epithelium morphology (HP:0012253)8.83106681
3Abnormal respiratory motile cilium morphology (HP:0005938)8.83106681
4Rhinitis (HP:0012384)7.83689270
5Abnormal ciliary motility (HP:0012262)7.35184326
6Chronic bronchitis (HP:0004469)7.08270231
7Infertility (HP:0000789)6.60410165
8Nasal polyposis (HP:0100582)6.45444516
9Severe visual impairment (HP:0001141)6.33693887
10Attenuation of retinal blood vessels (HP:0007843)5.37574582
11Abnormality of the nasal mucosa (HP:0000433)5.30019259
12Bony spicule pigmentary retinopathy (HP:0007737)5.16690875
13Hyperkalemia (HP:0002153)4.89267820
14Chronic hepatic failure (HP:0100626)4.80952542
15Nephronophthisis (HP:0000090)4.70368641
16Bronchiectasis (HP:0002110)4.62491610
17Bronchitis (HP:0012387)4.58550805
18Progressive cerebellar ataxia (HP:0002073)4.13763778
19Male infertility (HP:0003251)4.05496263
20Abnormality of macular pigmentation (HP:0008002)3.96896065
21Asymmetric septal hypertrophy (HP:0001670)3.93293349
22Abnormal rod and cone electroretinograms (HP:0008323)3.66569861
23Facial shape deformation (HP:0011334)3.66243451
24Potter facies (HP:0002009)3.66243451
25Resting tremor (HP:0002322)3.65921364
26Abnormality of the renal medulla (HP:0100957)3.58478308
27Genetic anticipation (HP:0003743)3.58336225
28Postural instability (HP:0002172)3.51741804
29Abnormal spermatogenesis (HP:0008669)3.36543850
30Recurrent otitis media (HP:0000403)3.33910883
31Cone-rod dystrophy (HP:0000548)3.29190206
32Recurrent sinusitis (HP:0011108)3.23235111
33Abnormality of the lower motor neuron (HP:0002366)3.16709208
34Hypoplasia of the thymus (HP:0000778)3.14884942
35Congenital sensorineural hearing impairment (HP:0008527)3.10288456
36Portal hypertension (HP:0001409)3.08861075
37Abnormality of potassium homeostasis (HP:0011042)3.06700376
38Tubulointerstitial nephritis (HP:0001970)3.02694779
39Gonadotropin excess (HP:0000837)2.99743877
40Recurrent bronchitis (HP:0002837)2.92071188
41Hypoplastic ischia (HP:0003175)2.89174953
42Amelogenesis imperfecta (HP:0000705)2.85054222
43Aplasia/Hypoplasia of the earlobes (HP:0009906)2.84899137
44Abnormality of the hepatic vasculature (HP:0006707)2.83927687
45Tubular atrophy (HP:0000092)2.81658049
46Abnormality of midbrain morphology (HP:0002418)2.72189180
47Molar tooth sign on MRI (HP:0002419)2.72189180
48Abnormality of dental color (HP:0011073)2.71597977
49Impulsivity (HP:0100710)2.68586306
50Tubulointerstitial abnormality (HP:0001969)2.63847861
51Abnormality of the ischium (HP:0003174)2.61092632
52Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.51321967
53Amyotrophic lateral sclerosis (HP:0007354)2.50198168
54Medial flaring of the eyebrow (HP:0010747)2.49627795
55Azoospermia (HP:0000027)2.44057414
56Abnormality of chloride homeostasis (HP:0011422)2.37725383
57Hypoalphalipoproteinemia (HP:0003233)2.34263354
58Renovascular hypertension (HP:0100817)2.31423451
59Progressive sensorineural hearing impairment (HP:0000408)2.27204463
60Pancreatic cysts (HP:0001737)2.27029607
61Menstrual irregularities (HP:0000858)2.25822377
62Fibular hypoplasia (HP:0003038)2.25651377
63Insulin-resistant diabetes mellitus (HP:0000831)2.19760965
64Gaze-evoked nystagmus (HP:0000640)2.18387513
65Tubulointerstitial fibrosis (HP:0005576)2.16355673
66Truncal obesity (HP:0001956)2.13705799
67Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.11545387
68Postaxial foot polydactyly (HP:0001830)2.11400676
69Recurrent pneumonia (HP:0006532)2.07883759
70Abnormal gallbladder physiology (HP:0012438)2.06772429
71Cholecystitis (HP:0001082)2.06772429
72Hypoplasia of the capital femoral epiphysis (HP:0003090)2.06445275
73Atonic seizures (HP:0010819)2.05900628
74Stage 5 chronic kidney disease (HP:0003774)2.03518196
75Impaired proprioception (HP:0010831)2.02598301
76Absent speech (HP:0001344)2.02374529
77Type II lissencephaly (HP:0007260)2.01884866
78Clumsiness (HP:0002312)2.00400713
79Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.3583408
80Dynein arm defect of respiratory motile cilia (HP:0012255)12.6684422
81Absent/shortened dynein arms (HP:0200106)12.6684422
82Pendular nystagmus (HP:0012043)1.98200197
83Scotoma (HP:0000575)1.97288853
84Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.96469772
85Generalized aminoaciduria (HP:0002909)1.96405932
86Hypokalemia (HP:0002900)1.96053136
87Abnormal drinking behavior (HP:0030082)1.95181499
88Polydipsia (HP:0001959)1.95181499
89Spastic tetraparesis (HP:0001285)1.94312208
90Congenital hepatic fibrosis (HP:0002612)1.93762435
91Short ribs (HP:0000773)1.90166267
92Abnormality of the renal cortex (HP:0011035)1.89590797
93Photophobia (HP:0000613)1.89388436
94Ileus (HP:0002595)1.85525122
95Absent frontal sinuses (HP:0002688)1.84279515
96Metabolic alkalosis (HP:0200114)1.83644433
97Heterotopia (HP:0002282)1.81274697
98Oculomotor apraxia (HP:0000657)1.80213475
99Optic nerve hypoplasia (HP:0000609)1.78048680
100Upper motor neuron abnormality (HP:0002127)1.75551744
101Renal dysplasia (HP:0000110)1.75429381
102True hermaphroditism (HP:0010459)1.75295848
103J-shaped sella turcica (HP:0002680)1.75168114
104Microglossia (HP:0000171)1.74754508
105Unilateral renal agenesis (HP:0000122)1.74263897
106Absent rod-and cone-mediated responses on ERG (HP:0007688)1.71007889
107Abnormality of binocular vision (HP:0011514)1.70763788
108Diplopia (HP:0000651)1.70763788
109Abnormality of dentin (HP:0010299)1.70289916
110Hypoalbuminemia (HP:0003073)1.70266535
111Abnormal albumin level (HP:0012116)1.70266535
112Enlarged epiphyses (HP:0010580)1.67600498
113Bell-shaped thorax (HP:0001591)1.67258330
114Hyperaldosteronism (HP:0000859)1.67104193
115Esophageal varix (HP:0002040)1.66975580
116Dyschromatopsia (HP:0007641)1.66755986
117Protruding tongue (HP:0010808)1.66447607
118Abnormality of permanent molar morphology (HP:0011071)1.65900822
119Abnormality of the dental root (HP:0006486)1.65900822
120Taurodontia (HP:0000679)1.65900822
121Central scotoma (HP:0000603)1.65298441
122Bulbous nose (HP:0000414)1.63977465
123Hyponatremia (HP:0002902)1.63760878
124Abnormality of renal excretion (HP:0011036)1.63092330
125Absent epiphyses (HP:0010577)1.63067527
126Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.63067527
127Degeneration of anterior horn cells (HP:0002398)1.62563263
128Abnormality of the anterior horn cell (HP:0006802)1.62563263
129Bile duct proliferation (HP:0001408)1.59268528
130Abnormal biliary tract physiology (HP:0012439)1.59268528
131Facial cleft (HP:0002006)1.59195552
132Postaxial hand polydactyly (HP:0001162)1.59168726
133Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.56608551
134Supernumerary spleens (HP:0009799)1.56225837
135Chronic sinusitis (HP:0011109)1.54823570
136Abnormality of molar morphology (HP:0011070)1.54187288
137Abnormality of molar (HP:0011077)1.54187288
138Deformed sella turcica (HP:0002681)1.51146347
139Abnormality of the dental pulp (HP:0006479)1.50394499
140Short thorax (HP:0010306)1.47352096
141Choroideremia (HP:0001139)1.45466106
142Decreased central vision (HP:0007663)1.43175913
143Median cleft lip (HP:0000161)1.41129312
144Cystic liver disease (HP:0006706)1.39375968
145Aplasia/Hypoplasia of the fibula (HP:0006492)1.37831479
146Broad distal phalanx of finger (HP:0009836)1.36346664
147Nephropathy (HP:0000112)1.35625667
148Aplasia/Hypoplasia of the tongue (HP:0010295)1.35392287
149Abnormal urine output (HP:0012590)1.34424712
150Abnormality of ocular smooth pursuit (HP:0000617)1.30998863
151Pachygyria (HP:0001302)1.29275821
152Pancreatic fibrosis (HP:0100732)1.29105470
153Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.27597761
154Aplasia/Hypoplasia of the lens (HP:0008063)1.25844542
155Congenital primary aphakia (HP:0007707)1.25443729
156Cerebellar dysplasia (HP:0007033)1.25202696
157Gait imbalance (HP:0002141)1.24783657
158Short femoral neck (HP:0100864)1.24016098
159Decreased motor nerve conduction velocity (HP:0003431)1.23563462
160Hemiparesis (HP:0001269)1.22552579
161Hemorrhage of the eye (HP:0011885)1.22022724
162Neurofibrillary tangles (HP:0002185)1.20065720
163Polyuria (HP:0000103)1.20035741
164Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.15426704

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK48.38231970
2PDK38.38231970
3FRK5.85598853
4TESK15.74611660
5PDK25.41670615
6PRKD34.81549290
7ICK3.94969028
8INSRR3.04865572
9PTK2B2.61699571
10PNCK2.57852381
11PIK3CG2.52892341
12WNK42.44161150
13DDR22.38423871
14BRD42.38193872
15PLK22.33812331
16STK392.33359036
17CAMKK22.30648523
18CAMK1D2.02354304
19NEK21.88572017
20STK381.70313611
21MAP4K21.42868397
22CAMK11.38013101
23TIE11.31815378
24VRK21.31683033
25DYRK1B1.24068970
26TAF11.21031817
27MST1R1.13634470
28WNK11.07803518
29MAPK151.07522476
30TYRO31.02662313
31PDK10.96871652
32ADRBK20.96004899
33ZAK0.86865895
34CAMK40.85722709
35STK30.84795600
36CCNB10.80493354
37PASK0.80121241
38PRKAA20.79273911
39VRK10.78782172
40MAP3K70.78164031
41GRK10.76433131
42DYRK30.74440678
43TTK0.72878897
44ACVR1B0.72640345
45CDC70.71220842
46SGK4940.70122874
47SGK2230.70122874
48CAMK1G0.69455865
49NTRK30.67471773
50CHUK0.66564440
51RPS6KA50.65755855
52NUAK10.60413817
53IRAK10.57467166
54PINK10.56757890
55PRKG20.55711373
56WEE10.55579548
57CHEK20.55327373
58EEF2K0.55081389
59MAP3K90.54191679
60LATS10.52746539
61TLK10.51647354
62AKT30.49365599
63SIK20.49111996
64CHEK10.48967529
65MAP2K20.48760901
66CDK70.48417683
67LMTK20.48248228
68TESK20.48171705
69PDPK10.46583865
70SGK20.46395641
71ATR0.44679442
72SGK10.44675380
73TNK20.43015126
74MAP2K60.40473665
75GRK50.39312363
76OXSR10.38735233
77PLK40.38067628
78RPS6KA60.37251776
79ATM0.36424360
80STK38L0.35602435
81PAK10.35421784
82PKN10.35248393
83MTOR0.34451236
84MAP3K20.34039628
85MELK0.33201726
86PAK20.30431190
87NTRK20.30189318
88ROCK10.29599330
89RIPK40.29394803
90ADRBK10.29276534
91MUSK0.29187346
92FER0.28436059
93MYLK0.28356946
94OBSCN0.27495231
95TXK0.26406415
96NEK60.25223989
97BMPR1B0.24653178
98IKBKB0.24567792
99IRAK20.24212515
100PRKAA10.24087695
101PRKCG0.23790497
102CDK120.23352361
103PRKCE0.23316598
104PLK10.22229951
105CAMKK10.21934492
106GRK70.20887339
107SMG10.20876389
108MARK20.20675096
109RPS6KB10.19420955
110PRKACA0.18943472
111RPS6KL10.18644770
112RPS6KC10.18644770
113RPS6KA20.17960567
114MAPKAPK50.17162258
115BRSK20.13499788
116PAK40.12153482
117CSNK1D0.08815321
118WNK30.08255893
119PAK60.08209861
120PRKCZ0.07568854
121PRKCQ0.06824253
122GSK3B0.06265152
123CDK10.06192415
124MAP3K40.06010029
125CDK20.05370523
126CSNK2A10.04797989
127MARK30.04591030
128BRAF0.04540553
129TAOK10.03998734
130CSF1R0.03685078
131STK100.03586663
132RPS6KA10.03386462
133CDK150.03299515
134STK110.02970913
135MAPK80.02875727
136BRSK10.02287883
137PRKDC0.01983534
138ZAP700.01779018
139PRKG10.01242854
140CDK180.01149190
141PRKACG0.00799917
142MAP3K100.00767041
143CSNK2A20.00638887
144PDGFRB0.00494235
145CDK11A0.00471954
146PRKACB0.00358986
147PRKCA-0.0394344
148MAPK10-0.0371633
149AURKA-0.0357437
150EPHB1-0.0333566
151MAPK1-0.0263050
152CDK14-0.0216924
153RPS6KA3-0.0173598
154CAMK2A-0.0163155
155EGFR-0.0109363
156CDK4-0.0107933
157CDK6-0.0066797
158PRKCB-0.0042845
159CDK3-0.0009132

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000724.49662169
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.28660835
3Vitamin B6 metabolism_Homo sapiens_hsa007504.13279555
4Pyruvate metabolism_Homo sapiens_hsa006203.90799072
5Fatty acid biosynthesis_Homo sapiens_hsa000613.80723081
6Olfactory transduction_Homo sapiens_hsa047403.37323884
7Propanoate metabolism_Homo sapiens_hsa006402.98878749
8Butanoate metabolism_Homo sapiens_hsa006502.93818845
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.80173260
10Glucagon signaling pathway_Homo sapiens_hsa049222.74613456
11Linoleic acid metabolism_Homo sapiens_hsa005912.67969503
12Dorso-ventral axis formation_Homo sapiens_hsa043202.60523115
13Basal transcription factors_Homo sapiens_hsa030222.57900698
14Selenocompound metabolism_Homo sapiens_hsa004502.42521095
15Fanconi anemia pathway_Homo sapiens_hsa034602.17915892
16Pentose phosphate pathway_Homo sapiens_hsa000302.09580753
17Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.09534040
18Carbohydrate digestion and absorption_Homo sapiens_hsa049732.04777039
19Glycerolipid metabolism_Homo sapiens_hsa005612.02652376
20Oocyte meiosis_Homo sapiens_hsa041141.99066068
21Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.97123507
22Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.96806606
23Nitrogen metabolism_Homo sapiens_hsa009101.92357934
24Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.91733072
25PPAR signaling pathway_Homo sapiens_hsa033201.73300280
26Huntingtons disease_Homo sapiens_hsa050161.66138479
27Tryptophan metabolism_Homo sapiens_hsa003801.65521085
28Phototransduction_Homo sapiens_hsa047441.63598225
29Glycerophospholipid metabolism_Homo sapiens_hsa005641.59018883
30Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.57820972
31Amphetamine addiction_Homo sapiens_hsa050311.55450026
32Fructose and mannose metabolism_Homo sapiens_hsa000511.53058743
33Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.50923607
34Nicotine addiction_Homo sapiens_hsa050331.43610613
35mRNA surveillance pathway_Homo sapiens_hsa030151.42658871
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.37654688
37Glutamatergic synapse_Homo sapiens_hsa047241.36634847
38Carbon metabolism_Homo sapiens_hsa012001.35439635
39Steroid hormone biosynthesis_Homo sapiens_hsa001401.30302234
40Glycosaminoglycan degradation_Homo sapiens_hsa005311.29990249
41RNA transport_Homo sapiens_hsa030131.29192093
42Primary bile acid biosynthesis_Homo sapiens_hsa001201.28056635
43Ether lipid metabolism_Homo sapiens_hsa005651.24187394
44Cardiac muscle contraction_Homo sapiens_hsa042601.24131572
45Antigen processing and presentation_Homo sapiens_hsa046121.23592279
46Fat digestion and absorption_Homo sapiens_hsa049751.23235340
47Renin secretion_Homo sapiens_hsa049241.23004502
48Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.21131452
49Fatty acid metabolism_Homo sapiens_hsa012121.20441093
50Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.18645055
51Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.16137580
52Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.14974920
53Morphine addiction_Homo sapiens_hsa050321.12212318
54Fatty acid degradation_Homo sapiens_hsa000711.11877383
55Mineral absorption_Homo sapiens_hsa049781.10839491
56Histidine metabolism_Homo sapiens_hsa003401.06436375
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.02388182
58Phenylalanine metabolism_Homo sapiens_hsa003601.01371332
59Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.96609555
60Purine metabolism_Homo sapiens_hsa002300.94414722
61Retinol metabolism_Homo sapiens_hsa008300.93958345
62Type II diabetes mellitus_Homo sapiens_hsa049300.85028710
63Biosynthesis of amino acids_Homo sapiens_hsa012300.84744169
64Long-term potentiation_Homo sapiens_hsa047200.82185284
65ABC transporters_Homo sapiens_hsa020100.81485174
66Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.81008139
67Serotonergic synapse_Homo sapiens_hsa047260.80579738
68Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.80360227
69Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.77973425
70Estrogen signaling pathway_Homo sapiens_hsa049150.77531588
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.75170722
72Caffeine metabolism_Homo sapiens_hsa002320.75128083
73Glutathione metabolism_Homo sapiens_hsa004800.72274948
74Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.71730095
75GABAergic synapse_Homo sapiens_hsa047270.71058753
76Arginine and proline metabolism_Homo sapiens_hsa003300.69320904
77Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.68790156
78Adipocytokine signaling pathway_Homo sapiens_hsa049200.68006202
79Central carbon metabolism in cancer_Homo sapiens_hsa052300.67582832
80Hedgehog signaling pathway_Homo sapiens_hsa043400.65424265
81beta-Alanine metabolism_Homo sapiens_hsa004100.65213252
82Transcriptional misregulation in cancer_Homo sapiens_hsa052020.63654668
83Oxytocin signaling pathway_Homo sapiens_hsa049210.63245360
84Graft-versus-host disease_Homo sapiens_hsa053320.62194111
85cGMP-PKG signaling pathway_Homo sapiens_hsa040220.61991334
86Gap junction_Homo sapiens_hsa045400.61195168
87Arachidonic acid metabolism_Homo sapiens_hsa005900.60861067
88Aldosterone synthesis and secretion_Homo sapiens_hsa049250.60486444
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.59757876
90Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57765693
91Cyanoamino acid metabolism_Homo sapiens_hsa004600.57600650
92Chemical carcinogenesis_Homo sapiens_hsa052040.56260207
93Insulin secretion_Homo sapiens_hsa049110.55859193
94Legionellosis_Homo sapiens_hsa051340.54854385
95Renin-angiotensin system_Homo sapiens_hsa046140.54478119
96Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.54472865
97Calcium signaling pathway_Homo sapiens_hsa040200.53681913
98AMPK signaling pathway_Homo sapiens_hsa041520.52534265
99Thyroid hormone synthesis_Homo sapiens_hsa049180.52134370
100Lysine degradation_Homo sapiens_hsa003100.51446341
101Endocytosis_Homo sapiens_hsa041440.50483001
102Systemic lupus erythematosus_Homo sapiens_hsa053220.50470541
103ECM-receptor interaction_Homo sapiens_hsa045120.49217568
104Bile secretion_Homo sapiens_hsa049760.49152690
105Arginine biosynthesis_Homo sapiens_hsa002200.49142278
106Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48327791
107VEGF signaling pathway_Homo sapiens_hsa043700.47144017
108Collecting duct acid secretion_Homo sapiens_hsa049660.45550786
109Cholinergic synapse_Homo sapiens_hsa047250.44898298
110Inositol phosphate metabolism_Homo sapiens_hsa005620.42862892
111N-Glycan biosynthesis_Homo sapiens_hsa005100.41659842
112Starch and sucrose metabolism_Homo sapiens_hsa005000.41596958
113Ovarian steroidogenesis_Homo sapiens_hsa049130.39321949
114Taste transduction_Homo sapiens_hsa047420.38237621
115Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.37661936
116Type I diabetes mellitus_Homo sapiens_hsa049400.37064518
117Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.37011889
118RNA degradation_Homo sapiens_hsa030180.35514553
119Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.34321385
120Protein digestion and absorption_Homo sapiens_hsa049740.33241067
121MAPK signaling pathway_Homo sapiens_hsa040100.33071981
122Vascular smooth muscle contraction_Homo sapiens_hsa042700.32227601
123Autoimmune thyroid disease_Homo sapiens_hsa053200.32143316
124Pancreatic secretion_Homo sapiens_hsa049720.32031926
125Metabolic pathways_Homo sapiens_hsa011000.31445913
126Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.30001622
127Tyrosine metabolism_Homo sapiens_hsa003500.29919381
128Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29626511
129Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.29171134
130Salivary secretion_Homo sapiens_hsa049700.26714021
131Circadian entrainment_Homo sapiens_hsa047130.26277538
132Synaptic vesicle cycle_Homo sapiens_hsa047210.25617599
133Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.23891765
134cAMP signaling pathway_Homo sapiens_hsa040240.23739290
135Pentose and glucuronate interconversions_Homo sapiens_hsa000400.23627797
136Alcoholism_Homo sapiens_hsa050340.23303783
137Gastric acid secretion_Homo sapiens_hsa049710.22325332
138Pyrimidine metabolism_Homo sapiens_hsa002400.20200936
139Homologous recombination_Homo sapiens_hsa034400.17178217
140Cell cycle_Homo sapiens_hsa041100.17148333
141Viral carcinogenesis_Homo sapiens_hsa052030.16895622
142B cell receptor signaling pathway_Homo sapiens_hsa046620.16794655
143Wnt signaling pathway_Homo sapiens_hsa043100.14384911
144Sphingolipid metabolism_Homo sapiens_hsa006000.14187343
145Cocaine addiction_Homo sapiens_hsa050300.12488877
146Longevity regulating pathway - mammal_Homo sapiens_hsa042110.12159810

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