MRPL14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This nuclear gene encodes a protein component of the 39S subunit of the mitochondrial ribosome. A pseudogene of this gene is found on chromosome 17. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1chaperone-mediated protein transport (GO:0072321)5.89931342
2establishment of protein localization to mitochondrial membrane (GO:0090151)5.32816310
3ribosomal small subunit assembly (GO:0000028)5.08977326
4protoporphyrinogen IX biosynthetic process (GO:0006782)4.44220539
5DNA deamination (GO:0045006)4.43129271
6mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.26978107
7protein targeting to mitochondrion (GO:0006626)4.20785997
8oxidative phosphorylation (GO:0006119)4.20465762
9ATP synthesis coupled proton transport (GO:0015986)4.08896346
10energy coupled proton transport, down electrochemical gradient (GO:0015985)4.08896346
11mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.02194898
12protoporphyrinogen IX metabolic process (GO:0046501)3.96881058
13ribosomal small subunit biogenesis (GO:0042274)3.96578585
14heme biosynthetic process (GO:0006783)3.93479077
15establishment of integrated proviral latency (GO:0075713)3.91930468
16rRNA modification (GO:0000154)3.90780887
17pseudouridine synthesis (GO:0001522)3.87243015
18respiratory electron transport chain (GO:0022904)3.85653053
19establishment of protein localization to mitochondrion (GO:0072655)3.85240748
20positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.82356931
21signal transduction involved in DNA integrity checkpoint (GO:0072401)3.81238195
22signal transduction involved in DNA damage checkpoint (GO:0072422)3.81238195
23viral transcription (GO:0019083)3.80161174
24protein localization to mitochondrion (GO:0070585)3.78184497
25electron transport chain (GO:0022900)3.75315982
26chromatin remodeling at centromere (GO:0031055)3.74591450
27signal transduction involved in cell cycle checkpoint (GO:0072395)3.74572178
28protein neddylation (GO:0045116)3.71661187
29CENP-A containing nucleosome assembly (GO:0034080)3.70777121
30translational termination (GO:0006415)3.66983580
31spliceosomal snRNP assembly (GO:0000387)3.65656503
32positive regulation of ligase activity (GO:0051351)3.65357294
33heme metabolic process (GO:0042168)3.64156024
34aldehyde catabolic process (GO:0046185)3.63519293
35ribonucleoprotein complex biogenesis (GO:0022613)3.63158564
36establishment of viral latency (GO:0019043)3.56692155
37L-phenylalanine metabolic process (GO:0006558)3.53369826
38erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.53369826
39DNA replication checkpoint (GO:0000076)3.48675436
40regulation of ubiquitin-protein transferase activity (GO:0051438)3.47692075
41nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.47467869
42rRNA processing (GO:0006364)3.47271417
43protein maturation by protein folding (GO:0022417)3.46164075
44exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.46108442
45cullin deneddylation (GO:0010388)3.45953486
46proteasome assembly (GO:0043248)3.44102304
47SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.42887392
48regulation of mitochondrial translation (GO:0070129)3.40466786
49ribosome assembly (GO:0042255)3.35346545
50protein deneddylation (GO:0000338)3.35074731
51regulation of ligase activity (GO:0051340)3.34854294
52pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.34264393
53DNA damage response, detection of DNA damage (GO:0042769)3.32284429
54DNA strand elongation involved in DNA replication (GO:0006271)3.32032794
55cotranslational protein targeting to membrane (GO:0006613)3.31255804
56protein targeting to ER (GO:0045047)3.30806864
57rRNA metabolic process (GO:0016072)3.30569341
58translational elongation (GO:0006414)3.30479371
59respiratory chain complex IV assembly (GO:0008535)3.25979398
60erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.23815879
61L-phenylalanine catabolic process (GO:0006559)3.23815879
62DNA strand elongation (GO:0022616)3.22958140
63mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.21791860
64mitochondrial respiratory chain complex I assembly (GO:0032981)3.21791860
65NADH dehydrogenase complex assembly (GO:0010257)3.21791860
66inner mitochondrial membrane organization (GO:0007007)3.21564315
67protein complex biogenesis (GO:0070271)3.21003716
68purine nucleoside triphosphate biosynthetic process (GO:0009145)3.20563873
69protein localization to endoplasmic reticulum (GO:0070972)3.20219859
70regulation of cellular amine metabolic process (GO:0033238)3.18974932
71mitotic metaphase plate congression (GO:0007080)3.18605626
72GTP biosynthetic process (GO:0006183)3.18313099
737-methylguanosine mRNA capping (GO:0006370)3.18197743
74kinetochore assembly (GO:0051382)3.17682808
75transcription-coupled nucleotide-excision repair (GO:0006283)3.17238764
76formation of translation preinitiation complex (GO:0001731)3.16585092
77purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.15866179
78ATP biosynthetic process (GO:0006754)3.15093467
79mitochondrial transport (GO:0006839)3.15007498
80mitochondrial respiratory chain complex assembly (GO:0033108)3.13679413
81tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.12861070
82RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.12861070
83deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.10631804
84glyoxylate metabolic process (GO:0046487)3.10300743
85establishment of protein localization to endoplasmic reticulum (GO:0072599)3.08239085
86aromatic amino acid family catabolic process (GO:0009074)3.08091936
87porphyrin-containing compound biosynthetic process (GO:0006779)3.06607723
88indole-containing compound catabolic process (GO:0042436)3.01038978
89indolalkylamine catabolic process (GO:0046218)3.01038978
90tryptophan catabolic process (GO:0006569)3.01038978
91cytochrome complex assembly (GO:0017004)3.00538420
92ribosomal large subunit biogenesis (GO:0042273)2.97511878
93viral life cycle (GO:0019058)2.95721979
94* translation (GO:0006412)2.93684338
95negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.89720940
96maturation of SSU-rRNA (GO:0030490)2.89279961
97triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.86901695
98cellular protein complex disassembly (GO:0043624)2.86826252
99porphyrin-containing compound metabolic process (GO:0006778)2.85421863
100amino acid salvage (GO:0043102)2.85361847
101L-methionine salvage (GO:0071267)2.85361847
102L-methionine biosynthetic process (GO:0071265)2.85361847
103tetrapyrrole biosynthetic process (GO:0033014)2.82758996
104tryptophan metabolic process (GO:0006568)2.82117889
105aerobic respiration (GO:0009060)2.79333949
106glycine metabolic process (GO:0006544)2.77600781
107branched-chain amino acid catabolic process (GO:0009083)2.76499250
108regulation of cellular amino acid metabolic process (GO:0006521)2.76412746
109antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.76091961
110L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.75545227
111translational initiation (GO:0006413)2.75254867
112pteridine-containing compound biosynthetic process (GO:0042559)2.73373870
113cellular ketone body metabolic process (GO:0046950)2.73087790
114kynurenine metabolic process (GO:0070189)2.69760905
115positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.65097828
116antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.63808355
117ubiquinone biosynthetic process (GO:0006744)2.62434826
118quinone biosynthetic process (GO:1901663)2.62434826
119iron-sulfur cluster assembly (GO:0016226)2.61926656
120metallo-sulfur cluster assembly (GO:0031163)2.61926656
1212-deoxyribonucleotide biosynthetic process (GO:0009265)2.61014567
122deoxyribose phosphate biosynthetic process (GO:0046385)2.61014567
123lysine catabolic process (GO:0006554)2.60934212
124lysine metabolic process (GO:0006553)2.60934212
125DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.58788863
126sulfur amino acid catabolic process (GO:0000098)2.57594818
127nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.57123486
128cofactor catabolic process (GO:0051187)2.56987799
129regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.56298156
130negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.55170469
131nucleobase-containing small molecule interconversion (GO:0015949)2.55114470
132termination of RNA polymerase III transcription (GO:0006386)2.53587998
133transcription elongation from RNA polymerase III promoter (GO:0006385)2.53587998
134negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.53286875
135negative regulation of ligase activity (GO:0051352)2.53286875
136regulation of cholesterol esterification (GO:0010872)2.53190756
137intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.51550566
138signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.51550566
139signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.50750398
140signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.50750398
141signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.50750398
142regulation of oxidative phosphorylation (GO:0002082)2.50258653
143cysteine metabolic process (GO:0006534)2.49444257
144cellular component biogenesis (GO:0044085)2.48920291
145serine family amino acid catabolic process (GO:0009071)2.48646102
146telomere maintenance via semi-conservative replication (GO:0032201)2.48639966
147anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.48361859
148serine family amino acid biosynthetic process (GO:0009070)2.48043648

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.07966616
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.86675823
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.63644233
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.59892701
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.28348400
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.23756156
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.16116053
8E2F7_22180533_ChIP-Seq_HELA_Human3.15086932
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.09794503
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.94054326
11CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.90775271
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.78559717
13EGR1_23403033_ChIP-Seq_LIVER_Mouse2.77854943
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.72603504
15RXR_22158963_ChIP-Seq_LIVER_Mouse2.60268269
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.58426053
17MYC_18358816_ChIP-ChIP_MESCs_Mouse2.56166149
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.50467257
19SRF_21415370_ChIP-Seq_HL-1_Mouse2.49546643
20PPARA_22158963_ChIP-Seq_LIVER_Mouse2.47939610
21E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.29275602
22CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.22436606
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.21611748
24E2F1_18555785_ChIP-Seq_MESCs_Mouse2.19963972
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.08982470
26MYC_19030024_ChIP-ChIP_MESCs_Mouse2.06455333
27DCP1A_22483619_ChIP-Seq_HELA_Human2.02986442
28FOXM1_23109430_ChIP-Seq_U2OS_Human1.97984038
29MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.96284439
30VDR_23849224_ChIP-Seq_CD4+_Human1.96278006
31XRN2_22483619_ChIP-Seq_HELA_Human1.94150748
32FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.91341837
33PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.89332337
34SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.87041639
35CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.86787676
36CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.86335864
37FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.84235988
38YY1_21170310_ChIP-Seq_MESCs_Mouse1.78114353
39HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.76054986
40MYC_19079543_ChIP-ChIP_MESCs_Mouse1.73330384
41IRF8_22096565_ChIP-ChIP_GC-B_Human1.72450608
42FOXP3_21729870_ChIP-Seq_TREG_Human1.70894402
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.69623599
44* GABP_19822575_ChIP-Seq_HepG2_Human1.65672901
45NELFA_20434984_ChIP-Seq_ESCs_Mouse1.64631398
46FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.63096270
47THAP11_20581084_ChIP-Seq_MESCs_Mouse1.62125650
48MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.61820580
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.59390912
50TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.57734302
51AR_21909140_ChIP-Seq_LNCAP_Human1.57692282
52YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.57071431
53FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.53122090
54* LXR_22158963_ChIP-Seq_LIVER_Mouse1.48418887
55IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.43961179
56PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.42543886
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.40629408
58* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.40544963
59CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.38952630
60TTF2_22483619_ChIP-Seq_HELA_Human1.36226361
61ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36181374
62PADI4_21655091_ChIP-ChIP_MCF-7_Human1.34666178
63STAT3_1855785_ChIP-Seq_MESCs_Mouse1.31878820
64BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.31251382
65KDM5A_27292631_Chip-Seq_BREAST_Human1.31223514
66POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.31051238
67BP1_19119308_ChIP-ChIP_Hs578T_Human1.30597156
68E2F4_17652178_ChIP-ChIP_JURKAT_Human1.28950630
69ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27374024
70ELK1_19687146_ChIP-ChIP_HELA_Human1.26710715
71NANOG_18555785_ChIP-Seq_MESCs_Mouse1.20617506
72CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.19902761
73ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.19884341
74TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.18381878
75DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.17748250
76DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.14392271
77SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13552792
78* HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.12071354
79SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.11230073
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.10525090
81RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.09866311
82CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.09424460
83ZNF263_19887448_ChIP-Seq_K562_Human1.09280618
84STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.07036137
85IRF8_21731497_ChIP-ChIP_J774_Mouse1.05948776
86SOX2_18555785_ChIP-Seq_MESCs_Mouse1.03302219
87RARG_19884340_ChIP-ChIP_MEFs_Mouse1.03089161
88POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.02047049
89CTCF_18555785_ChIP-Seq_MESCs_Mouse1.01480518
90GATA1_22383799_ChIP-Seq_G1ME_Mouse1.00951338
91MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.98418122
92POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.97811392
93ELK1_22589737_ChIP-Seq_MCF10A_Human0.97566619
94NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.96862762
95SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.95859651
96MYC_18940864_ChIP-ChIP_HL60_Human0.93906761
97SPI1_23547873_ChIP-Seq_NB4_Human0.93072989
98TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.91771738
99KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.91132058
100SOX17_20123909_ChIP-Seq_XEN_Mouse0.90873575
101CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.89339926
102MYCN_18555785_ChIP-Seq_MESCs_Mouse0.88838949
103STAT4_19710469_ChIP-ChIP_TH1__Mouse0.88081861
104NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.87798475
105EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.87510695
106FOXP1_21924763_ChIP-Seq_HESCs_Human0.86405395
107BCL6_27268052_Chip-Seq_Bcells_Human0.85262486
108TBX5_21415370_ChIP-Seq_HL-1_Mouse0.84953869
109GATA1_22025678_ChIP-Seq_K562_Human0.84170048
110E2F1_21310950_ChIP-Seq_MCF-7_Human0.83988098
111* SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.83499852
112NOTCH1_21737748_ChIP-Seq_TLL_Human0.81838295
113TFEB_21752829_ChIP-Seq_HELA_Human0.81712292
114OCT4_18692474_ChIP-Seq_MEFs_Mouse0.81468591
115KLF4_18555785_ChIP-Seq_MESCs_Mouse0.81264513
116RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.80898959
117NANOG_16153702_ChIP-ChIP_HESCs_Human0.80244947
118* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.79048625
119CIITA_25753668_ChIP-Seq_RAJI_Human0.78792872
120* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.78489567
121SOX2_18692474_ChIP-Seq_MEFs_Mouse0.78353192
122NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.77391007
123ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.76181143
124ELF5_23300383_ChIP-Seq_T47D_Human0.71948103
125GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.71206127
126SRY_22984422_ChIP-ChIP_TESTIS_Rat0.69277168
127SOX2_16153702_ChIP-ChIP_HESCs_Human0.69219665
128HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.65838317

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.38999022
2MP0003806_abnormal_nucleotide_metabolis4.32405501
3MP0005360_urolithiasis4.23841056
4MP0005085_abnormal_gallbladder_physiolo3.50995731
5MP0005365_abnormal_bile_salt3.06197322
6MP0003186_abnormal_redox_activity2.94397038
7MP0008875_abnormal_xenobiotic_pharmacok2.93829291
8MP0008932_abnormal_embryonic_tissue2.87441262
9MP0009379_abnormal_foot_pigmentation2.83594288
10MP0006036_abnormal_mitochondrial_physio2.67980782
11MP0009840_abnormal_foam_cell2.67905640
12MP0000372_irregular_coat_pigmentation2.62649085
13MP0006292_abnormal_olfactory_placode2.51484064
14MP0003693_abnormal_embryo_hatching2.44868229
15MP0002938_white_spotting2.30248646
16MP0003195_calcinosis2.28305770
17MP0003646_muscle_fatigue2.25274765
18MP0010030_abnormal_orbit_morphology2.16285126
19MP0003123_paternal_imprinting2.14568553
20MP0005332_abnormal_amino_acid2.05577868
21MP0003941_abnormal_skin_development2.00165631
22MP0001764_abnormal_homeostasis1.96595600
23MP0001835_abnormal_antigen_presentation1.92320933
24MP0003191_abnormal_cellular_cholesterol1.86171662
25MP0003656_abnormal_erythrocyte_physiolo1.85780833
26MP0002132_abnormal_respiratory_system1.82908424
27MP0005083_abnormal_biliary_tract1.71897275
28MP0003252_abnormal_bile_duct1.70117741
29MP0005319_abnormal_enzyme/_coenzyme1.69665052
30MP0005451_abnormal_body_composition1.69257806
31MP0009785_altered_susceptibility_to1.65793774
32MP0009697_abnormal_copulation1.62860112
33MP0010329_abnormal_lipoprotein_level1.62058760
34MP0001529_abnormal_vocalization1.55986307
35MP0002102_abnormal_ear_morphology1.52339856
36MP0002163_abnormal_gland_morphology1.51571951
37MP0006035_abnormal_mitochondrial_morpho1.51479394
38MP0002138_abnormal_hepatobiliary_system1.50224140
39MP0001293_anophthalmia1.45164407
40MP0004019_abnormal_vitamin_homeostasis1.44719515
41MP0000358_abnormal_cell_content/1.43332847
42MP0002837_dystrophic_cardiac_calcinosis1.43318359
43MP0001853_heart_inflammation1.42428309
44MP0001666_abnormal_nutrient_absorption1.39894186
45MP0009643_abnormal_urine_homeostasis1.37011696
46MP0000609_abnormal_liver_physiology1.36509279
47MP0004147_increased_porphyrin_level1.35575561
48MP0000350_abnormal_cell_proliferation1.33599449
49MP0008789_abnormal_olfactory_epithelium1.32373475
50MP0002148_abnormal_hypersensitivity_rea1.31862787
51MP0004957_abnormal_blastocyst_morpholog1.31666826
52MP0008469_abnormal_protein_level1.28798837
53MP0003718_maternal_effect1.28510333
54MP0000749_muscle_degeneration1.27934811
55MP0003724_increased_susceptibility_to1.27889594
56MP0003436_decreased_susceptibility_to1.27444835
57MP0002277_abnormal_respiratory_mucosa1.24149124
58MP0005636_abnormal_mineral_homeostasis1.22400496
59MP0009764_decreased_sensitivity_to1.22007144
60MP0003315_abnormal_perineum_morphology1.21346775
61MP0004782_abnormal_surfactant_physiolog1.21281166
62MP0005584_abnormal_enzyme/coenzyme_acti1.20261096
63MP0001730_embryonic_growth_arrest1.17875903
64MP0002160_abnormal_reproductive_system1.17292527
65MP0001697_abnormal_embryo_size1.15582051
66MP0008058_abnormal_DNA_repair1.14888711
67MP0005266_abnormal_metabolism1.14685978
68MP0005330_cardiomyopathy1.14571587
69MP0000566_synostosis1.14457291
70MP0005408_hypopigmentation1.13429670
71MP0000490_abnormal_crypts_of1.12856457
72MP0005025_abnormal_response_to1.09564629
73MP0000313_abnormal_cell_death1.09290436
74MP0003011_delayed_dark_adaptation1.09192079
75MP0000685_abnormal_immune_system1.07299060
76MP0006072_abnormal_retinal_apoptosis1.05292294
77MP0005084_abnormal_gallbladder_morpholo1.05271654
78MP0003950_abnormal_plasma_membrane1.03718745
79MP0005376_homeostasis/metabolism_phenot1.03624183
80MP0005670_abnormal_white_adipose1.01081679
81MP0002118_abnormal_lipid_homeostasis1.00941524
82MP0003077_abnormal_cell_cycle1.00691841
83MP0001881_abnormal_mammary_gland1.00150608
84MP0002396_abnormal_hematopoietic_system1.00103742
85MP0002210_abnormal_sex_determination1.00028258
86MP0000343_altered_response_to0.98916625
87MP0003567_abnormal_fetal_cardiomyocyte0.97666035
88MP0000750_abnormal_muscle_regeneration0.97401080
89MP0001905_abnormal_dopamine_level0.95485123
90MP0000598_abnormal_liver_morphology0.95254884
91MP0003136_yellow_coat_color0.94840680
92MP0009763_increased_sensitivity_to0.94464994
93MP0009333_abnormal_splenocyte_physiolog0.94268002
94MP0010094_abnormal_chromosome_stability0.93551794
95MP0003221_abnormal_cardiomyocyte_apopto0.92116562
96MP0002876_abnormal_thyroid_physiology0.90714983
97MP0000049_abnormal_middle_ear0.89525440
98MP0002419_abnormal_innate_immunity0.88129932
99MP0003111_abnormal_nucleus_morphology0.88078212
100MP0008007_abnormal_cellular_replicative0.87846039
101MP0001756_abnormal_urination0.86222012
102MP0001727_abnormal_embryo_implantation0.85970009
103MP0002080_prenatal_lethality0.85813956
104MP0005389_reproductive_system_phenotype0.85066293
105MP0001672_abnormal_embryogenesis/_devel0.83656379
106MP0005380_embryogenesis_phenotype0.83656379
107MP0008995_early_reproductive_senescence0.83488352
108MP0002095_abnormal_skin_pigmentation0.82963122
109MP0001845_abnormal_inflammatory_respons0.82669581
110MP0003786_premature_aging0.82024499
111MP0005671_abnormal_response_to0.80118378
112MP0009642_abnormal_blood_homeostasis0.78898604
113MP0005464_abnormal_platelet_physiology0.78670884
114MP0004145_abnormal_muscle_electrophysio0.78572731
115MP0001929_abnormal_gametogenesis0.78511814
116MP0006082_CNS_inflammation0.77846270
117MP0002085_abnormal_embryonic_tissue0.77208022
118MP0010155_abnormal_intestine_physiology0.76653560
119MP0001542_abnormal_bone_strength0.75402489
120MP0001145_abnormal_male_reproductive0.74872527
121MP0005379_endocrine/exocrine_gland_phen0.74794443
122MP0005000_abnormal_immune_tolerance0.74409245
123MP0002090_abnormal_vision0.73846950
124MP0001663_abnormal_digestive_system0.72856828
125MP0000653_abnormal_sex_gland0.72048887
126MP0002736_abnormal_nociception_after0.71838255
127MP0005395_other_phenotype0.71806147
128MP0000647_abnormal_sebaceous_gland0.71573556
129MP0005397_hematopoietic_system_phenotyp0.71150379
130MP0001545_abnormal_hematopoietic_system0.71150379
131MP0003937_abnormal_limbs/digits/tail_de0.71138594
132MP0002177_abnormal_outer_ear0.70668909
133MP0001346_abnormal_lacrimal_gland0.70346449
134MP0010368_abnormal_lymphatic_system0.70269731
135MP0004084_abnormal_cardiac_muscle0.70170172
136MP0005075_abnormal_melanosome_morpholog0.70166140
137MP0002234_abnormal_pharynx_morphology0.68999402
138MP0005410_abnormal_fertilization0.68415491
139MP0002282_abnormal_trachea_morphology0.67747536
140MP0002723_abnormal_immune_serum0.67300180
141MP0005501_abnormal_skin_physiology0.66001727
142MP0003938_abnormal_ear_development0.65518334
143MP0003984_embryonic_growth_retardation0.65517098
144MP0000689_abnormal_spleen_morphology0.64296752
145MP0002019_abnormal_tumor_incidence0.63615158
146MP0005220_abnormal_exocrine_pancreas0.63528240
147MP0002452_abnormal_antigen_presenting0.63527862
148MP0002405_respiratory_system_inflammati0.63521769
149MP0001485_abnormal_pinna_reflex0.63315785
150MP0001800_abnormal_humoral_immune0.62293863
151MP0002638_abnormal_pupillary_reflex0.62181825
152MP0002088_abnormal_embryonic_growth/wei0.61854841
153MP0003828_pulmonary_edema0.61556312
154MP0002429_abnormal_blood_cell0.61531130
155MP0000858_altered_metastatic_potential0.61296286
156MP0003763_abnormal_thymus_physiology0.60956950
157MP0005385_cardiovascular_system_phenoty0.60393167
158MP0001544_abnormal_cardiovascular_syste0.60393167
159MP0008873_increased_physiological_sensi0.58922378
160MP0002111_abnormal_tail_morphology0.58756547
161MP0002233_abnormal_nose_morphology0.58191050
162MP0001119_abnormal_female_reproductive0.55638058
163MP0005367_renal/urinary_system_phenotyp0.55399746
164MP0000516_abnormal_urinary_system0.55399746
165MP0003936_abnormal_reproductive_system0.55230236
166MP0000762_abnormal_tongue_morphology0.54685809

Predicted human phenotypes

RankGene SetZ-score
1Hepatic necrosis (HP:0002605)4.80408777
2Acute necrotizing encephalopathy (HP:0006965)4.67214153
3Hepatocellular necrosis (HP:0001404)4.50756814
4Abnormal mitochondria in muscle tissue (HP:0008316)4.50290880
5Mitochondrial inheritance (HP:0001427)4.32738903
6Acute encephalopathy (HP:0006846)4.32050999
7Abnormality of the heme biosynthetic pathway (HP:0010472)4.16826561
8Increased CSF lactate (HP:0002490)4.00534124
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.94352357
10Decreased activity of mitochondrial respiratory chain (HP:0008972)3.94352357
11Abnormality of aromatic amino acid family metabolism (HP:0004338)3.88693119
12Cerebral edema (HP:0002181)3.88065724
13Progressive macrocephaly (HP:0004481)3.68317439
14Cerebral palsy (HP:0100021)3.49251566
15Lactic acidosis (HP:0003128)3.35769364
16Increased serum lactate (HP:0002151)3.35734544
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.33803311
18Lipid accumulation in hepatocytes (HP:0006561)3.29477124
19Abnormal number of erythroid precursors (HP:0012131)3.26195048
20Abnormality of cells of the erythroid lineage (HP:0012130)3.23314764
21Increased hepatocellular lipid droplets (HP:0006565)3.21355956
22Generalized aminoaciduria (HP:0002909)3.19459431
23Abnormality of fatty-acid metabolism (HP:0004359)3.18740393
24Increased intramyocellular lipid droplets (HP:0012240)3.17529962
25Nausea (HP:0002018)3.15151326
26Abnormality of monocarboxylic acid metabolism (HP:0010996)3.10580433
27Increased muscle lipid content (HP:0009058)3.10522256
28Abnormality of dicarboxylic acid metabolism (HP:0010995)3.02286739
29Dicarboxylic aciduria (HP:0003215)3.02286739
30Lethargy (HP:0001254)3.00065789
31Respiratory failure (HP:0002878)2.95141603
32Hypoglycemic coma (HP:0001325)2.95017565
33Exercise intolerance (HP:0003546)2.94324114
34Prolonged partial thromboplastin time (HP:0003645)2.92806533
353-Methylglutaconic aciduria (HP:0003535)2.87846351
36Hypobetalipoproteinemia (HP:0003563)2.83848154
37Hyperammonemia (HP:0001987)2.82130572
38Renal Fanconi syndrome (HP:0001994)2.81920361
39Reticulocytopenia (HP:0001896)2.79672241
40Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.74972488
41Abnormality of urine glucose concentration (HP:0011016)2.71977335
42Glycosuria (HP:0003076)2.71977335
43Abnormality of pyrimidine metabolism (HP:0004353)2.65327315
44Exertional dyspnea (HP:0002875)2.61800308
45Intrahepatic cholestasis (HP:0001406)2.59706861
46Degeneration of anterior horn cells (HP:0002398)2.55757952
47Abnormality of the anterior horn cell (HP:0006802)2.55757952
48Hyperglycinuria (HP:0003108)2.53191131
49Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.52718906
50Abnormality of glycolysis (HP:0004366)2.52642711
51Increased serum pyruvate (HP:0003542)2.52642711
52Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.52549563
53Abnormality of alanine metabolism (HP:0010916)2.52549563
54Hyperalaninemia (HP:0003348)2.52549563
55Vomiting (HP:0002013)2.43836196
56Methylmalonic aciduria (HP:0012120)2.42482795
57Metabolic acidosis (HP:0001942)2.41815282
58Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.40871473
59Abnormal protein N-linked glycosylation (HP:0012347)2.40871473
60Abnormal protein glycosylation (HP:0012346)2.40871473
61Abnormal glycosylation (HP:0012345)2.40871473
62CNS demyelination (HP:0007305)2.37906291
63Testicular atrophy (HP:0000029)2.37670575
64Paralysis (HP:0003470)2.37132127
65Sparse eyelashes (HP:0000653)2.35146648
66Xanthomatosis (HP:0000991)2.34419231
67Hyperglycinemia (HP:0002154)2.33988033
68Palpitations (HP:0001962)2.32570351
69Cerebral hypomyelination (HP:0006808)2.32342768
70Abnormality of renal resorption (HP:0011038)2.30493411
71Abnormality of serum amino acid levels (HP:0003112)2.28355026
72Macrocytic anemia (HP:0001972)2.26919601
73Pancytopenia (HP:0001876)2.26488414
74Rough bone trabeculation (HP:0100670)2.25104062
75Ragged-red muscle fibers (HP:0003200)2.23922236
76Joint hemorrhage (HP:0005261)2.23612640
77Deep venous thrombosis (HP:0002625)2.22668065
78Reduced antithrombin III activity (HP:0001976)2.21570139
79Ketosis (HP:0001946)2.20110240
80Microretrognathia (HP:0000308)2.18676950
81Respiratory difficulties (HP:0002880)2.18566791
82Multiple enchondromatosis (HP:0005701)2.18552845
83Abnormality of serine family amino acid metabolism (HP:0010894)2.18171279
84Abnormality of glycine metabolism (HP:0010895)2.18171279
85Hyperbilirubinemia (HP:0002904)2.17410020
86X-linked dominant inheritance (HP:0001423)2.17260383
87Abnormality of methionine metabolism (HP:0010901)2.16177042
88Microvesicular hepatic steatosis (HP:0001414)2.15490525
89Increased serum ferritin (HP:0003281)2.14810728
90Rhabdomyolysis (HP:0003201)2.14437378
91Proximal tubulopathy (HP:0000114)2.12987772
92Cleft eyelid (HP:0000625)2.12037380
93Abnormality of aspartate family amino acid metabolism (HP:0010899)2.11720784
94Emotional lability (HP:0000712)2.10317130
95Amniotic constriction ring (HP:0009775)2.09240404
96Abnormality of placental membranes (HP:0011409)2.09240404
97Hypercholesterolemia (HP:0003124)2.09110224
98Methylmalonic acidemia (HP:0002912)2.08920822
99Hypolipoproteinemia (HP:0010981)2.08602922
100Hyperlipoproteinemia (HP:0010980)2.05386623
101Meckel diverticulum (HP:0002245)2.04192931
102Delayed CNS myelination (HP:0002188)2.03474476
103Hypoplastic pelvis (HP:0008839)1.99853812
104Abnormality of the preputium (HP:0100587)1.99796930
105Type I transferrin isoform profile (HP:0003642)1.99501653
106Abnormality of iron homeostasis (HP:0011031)1.98649088
107Optic disc pallor (HP:0000543)1.97771920
108Aplastic anemia (HP:0001915)1.97210129
109Pallor (HP:0000980)1.96042040
110Progressive muscle weakness (HP:0003323)1.95242590
111Abnormality of glutamine family amino acid metabolism (HP:0010902)1.94853051
112Hyperphosphaturia (HP:0003109)1.93685132
113Abnormality of the ileum (HP:0001549)1.92153521
114Oral leukoplakia (HP:0002745)1.92148363
115Gliosis (HP:0002171)1.92137492
116Leukodystrophy (HP:0002415)1.90227606
117Abnormality of nucleobase metabolism (HP:0010932)1.89372832
118Blindness (HP:0000618)1.89115432
119Renal cortical cysts (HP:0000803)1.89087441
120Aplasia/hypoplasia of the uterus (HP:0008684)1.88609287
121Abnormality of the intrinsic pathway (HP:0010989)1.88518110
122Abnormality of transition element cation homeostasis (HP:0011030)1.87670256
123Opisthotonus (HP:0002179)1.86986829
124Megaloblastic anemia (HP:0001889)1.86318130
125Aplasia/Hypoplasia of the sacrum (HP:0008517)1.86251695
126Myoglobinuria (HP:0002913)1.85725283
127Birth length less than 3rd percentile (HP:0003561)1.85676837
128Congenital, generalized hypertrichosis (HP:0004540)1.85295943
129Ketoacidosis (HP:0001993)1.84825146
130Abnormality of sulfur amino acid metabolism (HP:0004339)1.84743959
131Absent thumb (HP:0009777)1.83642103
132Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.83365651
133Systemic lupus erythematosus (HP:0002725)1.83268892
134Brushfield spots (HP:0001088)1.82695209
135Conjunctival hamartoma (HP:0100780)1.81937090
136Facial cleft (HP:0002006)1.81612843
137Abnormal trabecular bone morphology (HP:0100671)1.76623570
138Chromosomal breakage induced by crosslinking agents (HP:0003221)1.70198630
139Horseshoe kidney (HP:0000085)1.70110593
140Secondary amenorrhea (HP:0000869)1.69869858
141Gout (HP:0001997)1.67790109
142Abnormal number of incisors (HP:0011064)1.66385245
143Progressive microcephaly (HP:0000253)1.65824558
144Aplasia/Hypoplasia of the uvula (HP:0010293)1.64690050

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.98649558
2NME24.48219632
3BCKDK3.97528082
4BUB12.86457091
5EIF2AK12.80266253
6STK162.65722479
7PIM22.52202181
8CDC72.39775515
9PBK1.97742681
10IRAK31.95833883
11MAP3K111.91661419
12PDK21.88508618
13TLK11.85830326
14MYLK1.81450491
15EIF2AK31.77758916
16SRPK11.73180665
17MAP3K31.70515192
18NME11.67958662
19NEK91.66793767
20PLK31.61661267
21IRAK41.61346115
22KDR1.60388909
23OBSCN1.57569112
24PLK41.50644750
25MST1R1.48095970
26ERN11.47400930
27MAP2K31.46562626
28WEE11.45488141
29ZAK1.42800119
30TBK11.33159930
31ABL21.30158500
32TEC1.27560748
33FLT31.23960324
34VRK11.22525526
35TYK21.16889740
36STK38L1.15135998
37BRSK11.14305564
38MAP4K11.12733533
39PAK41.11453731
40TXK1.11053272
41ACVR1B1.10999184
42NEK11.10929655
43BRAF1.10776358
44RPS6KA41.08128610
45PIK3CG1.08015002
46IKBKB1.07773151
47KIT1.07422440
48TAOK21.05738763
49DYRK31.04092711
50EPHA21.02083980
51PIM11.01399583
52CSNK1G31.01251207
53TAF11.00768540
54ARAF1.00628477
55TESK10.96054888
56CDK80.95273509
57MUSK0.94858568
58TRIM280.94727846
59DYRK20.94306802
60CSNK1G10.92187070
61AURKB0.90294198
62ILK0.89107398
63MAP3K140.89007580
64TGFBR10.88584033
65SIK30.87057603
66PLK10.86634003
67DAPK10.86456846
68LRRK20.84302463
69MAP4K20.83499906
70IKBKE0.82171244
71MAPKAPK30.80329216
72TIE10.79684931
73EIF2AK20.78986983
74AURKA0.78779090
75STK40.76925615
76PINK10.75071998
77RPS6KB20.73393965
78MAP3K120.71424818
79CSNK1A1L0.70884510
80PRKCI0.70250428
81CSNK1G20.69332655
82STK240.68693012
83JAK30.68250470
84CSNK2A20.68075343
85BMPR1B0.67954138
86MAP2K70.66944898
87CCNB10.66827212
88WNK30.66358530
89DAPK30.64598500
90RPS6KA50.63921553
91BTK0.63756104
92ZAP700.62567522
93PAK10.61973147
94GRK10.61493565
95NEK20.60362545
96SCYL20.59844002
97CSNK2A10.59727238
98CHUK0.59557161
99PKN20.58650810
100TESK20.58349516
101LIMK10.57989617
102MAP3K50.57079793
103MAP3K80.55917144
104CHEK20.55762584
105TTK0.54357001
106CDK190.53304178
107STK100.52106339
108BLK0.51700738
109PHKG20.49891536
110PHKG10.49891536
111CHEK10.48805489
112BRSK20.48716885
113TAOK30.48613417
114MAPK110.48419969
115BMPR20.48081733
116ATR0.46990321
117MAP2K60.46522355
118MKNK10.45717461
119CDK40.45495984
120INSRR0.44737918
121PRKCD0.44410277
122PRKG20.44077062
123FGFR40.43802284
124MST40.43532496
125NUAK10.42230073
126MAP3K60.41895886
127MAP2K20.41889830
128CDK70.41412465
129SYK0.41219310
130TGFBR20.40497252
131ERBB40.40338298
132YES10.40189386
133TSSK60.38930950
134ADRBK20.36696124
135MKNK20.35757067
136ATM0.34834602
137TNIK0.33978529
138AKT20.29324704
139OXSR10.28283039
140MAPKAPK50.27366106
141CSNK1A10.25578703
142CSNK1E0.25380162
143CAMK2G0.24555194
144STK30.23105969
145PASK0.20724682

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030103.25074788
2Oxidative phosphorylation_Homo sapiens_hsa001902.80351542
3Proteasome_Homo sapiens_hsa030502.77425965
4Parkinsons disease_Homo sapiens_hsa050122.61569185
5Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008602.47001073
6DNA replication_Homo sapiens_hsa030302.18460403
7Primary bile acid biosynthesis_Homo sapiens_hsa001202.04569679
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.04437799
9Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.04437649
10Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.94172155
11Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.90039052
12Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.87201361
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.84632879
14Folate biosynthesis_Homo sapiens_hsa007901.83429734
15Pentose and glucuronate interconversions_Homo sapiens_hsa000401.82656621
16Fatty acid degradation_Homo sapiens_hsa000711.81590598
17Huntingtons disease_Homo sapiens_hsa050161.77648098
18RNA polymerase_Homo sapiens_hsa030201.77459129
19Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.76012265
20Peroxisome_Homo sapiens_hsa041461.72164146
21Propanoate metabolism_Homo sapiens_hsa006401.70190239
22Alzheimers disease_Homo sapiens_hsa050101.65453204
23Drug metabolism - other enzymes_Homo sapiens_hsa009831.65240038
24Pyrimidine metabolism_Homo sapiens_hsa002401.65106179
25Mismatch repair_Homo sapiens_hsa034301.56146221
26Sulfur relay system_Homo sapiens_hsa041221.55460461
272-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.52857748
28Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.50227400
29One carbon pool by folate_Homo sapiens_hsa006701.48220404
30Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.48061602
31Tryptophan metabolism_Homo sapiens_hsa003801.47263712
32Carbon metabolism_Homo sapiens_hsa012001.46333128
33Sulfur metabolism_Homo sapiens_hsa009201.44064202
34Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.42378788
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.41456008
36Chemical carcinogenesis_Homo sapiens_hsa052041.38150278
37Homologous recombination_Homo sapiens_hsa034401.30496245
38Base excision repair_Homo sapiens_hsa034101.29353247
39Selenocompound metabolism_Homo sapiens_hsa004501.28691446
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.28603243
41Pyruvate metabolism_Homo sapiens_hsa006201.28244263
42Butanoate metabolism_Homo sapiens_hsa006501.22946729
43Protein export_Homo sapiens_hsa030601.22675151
44Glutathione metabolism_Homo sapiens_hsa004801.22662901
45Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.19913279
46beta-Alanine metabolism_Homo sapiens_hsa004101.19350480
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.18663426
48Complement and coagulation cascades_Homo sapiens_hsa046101.18335457
49Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.17124715
50Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.12075680
51Arginine biosynthesis_Homo sapiens_hsa002201.09000565
52Biosynthesis of amino acids_Homo sapiens_hsa012301.06695008
53Steroid hormone biosynthesis_Homo sapiens_hsa001401.05844157
54Pentose phosphate pathway_Homo sapiens_hsa000301.04685504
55Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.04215607
56Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.03908871
57Fatty acid elongation_Homo sapiens_hsa000621.02888881
58Retinol metabolism_Homo sapiens_hsa008301.01310498
59Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.01068104
60Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.99042795
61Phenylalanine metabolism_Homo sapiens_hsa003600.95651786
62Histidine metabolism_Homo sapiens_hsa003400.95133940
63Nucleotide excision repair_Homo sapiens_hsa034200.92892932
64Spliceosome_Homo sapiens_hsa030400.92784596
65Fatty acid metabolism_Homo sapiens_hsa012120.92721824
66Tyrosine metabolism_Homo sapiens_hsa003500.92359354
67Staphylococcus aureus infection_Homo sapiens_hsa051500.91128516
68Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.89032259
69Metabolic pathways_Homo sapiens_hsa011000.86503759
70Starch and sucrose metabolism_Homo sapiens_hsa005000.84373805
71Steroid biosynthesis_Homo sapiens_hsa001000.83563521
72Caffeine metabolism_Homo sapiens_hsa002320.82539107
73PPAR signaling pathway_Homo sapiens_hsa033200.79640437
74Arginine and proline metabolism_Homo sapiens_hsa003300.79359265
75Galactose metabolism_Homo sapiens_hsa000520.79061764
76Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77155141
77Cardiac muscle contraction_Homo sapiens_hsa042600.72497457
78Purine metabolism_Homo sapiens_hsa002300.72399136
79Fructose and mannose metabolism_Homo sapiens_hsa000510.68581786
80Cyanoamino acid metabolism_Homo sapiens_hsa004600.67308128
81Arachidonic acid metabolism_Homo sapiens_hsa005900.65009299
82Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61123864
83Maturity onset diabetes of the young_Homo sapiens_hsa049500.61106397
84N-Glycan biosynthesis_Homo sapiens_hsa005100.57688711
85Fat digestion and absorption_Homo sapiens_hsa049750.54260599
86RNA degradation_Homo sapiens_hsa030180.51027669
87Collecting duct acid secretion_Homo sapiens_hsa049660.50940193
88p53 signaling pathway_Homo sapiens_hsa041150.50007632
89RNA transport_Homo sapiens_hsa030130.47358748
90Legionellosis_Homo sapiens_hsa051340.44031928
91Epstein-Barr virus infection_Homo sapiens_hsa051690.42174617
92Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41428974
93RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.40951046
94Cell cycle_Homo sapiens_hsa041100.40772890
95Regulation of autophagy_Homo sapiens_hsa041400.40643560
96Basal transcription factors_Homo sapiens_hsa030220.38191327
97Linoleic acid metabolism_Homo sapiens_hsa005910.36875320
98Intestinal immune network for IgA production_Homo sapiens_hsa046720.36712956
99Vitamin B6 metabolism_Homo sapiens_hsa007500.36289461
100Vibrio cholerae infection_Homo sapiens_hsa051100.34872283
101Other glycan degradation_Homo sapiens_hsa005110.34546372
102mRNA surveillance pathway_Homo sapiens_hsa030150.33325632
103Oocyte meiosis_Homo sapiens_hsa041140.32191541
104Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.30377394
105Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.29903378
106ABC transporters_Homo sapiens_hsa020100.29259526
107Non-homologous end-joining_Homo sapiens_hsa034500.29207938
108Fanconi anemia pathway_Homo sapiens_hsa034600.28784736
109Vitamin digestion and absorption_Homo sapiens_hsa049770.28773757
110Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.26718098
111Systemic lupus erythematosus_Homo sapiens_hsa053220.24961116
112alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.24792787
113Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.24704566
114Herpes simplex infection_Homo sapiens_hsa051680.23577819
115SNARE interactions in vesicular transport_Homo sapiens_hsa041300.22277635
116Mineral absorption_Homo sapiens_hsa049780.20847463

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