MRPL15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.27590054
2chaperone-mediated protein transport (GO:0072321)4.89594743
3maturation of SSU-rRNA (GO:0030490)4.78245708
4purine nucleobase biosynthetic process (GO:0009113)4.71158657
5nucleobase biosynthetic process (GO:0046112)4.70153459
6establishment of protein localization to mitochondrial membrane (GO:0090151)4.69071940
7ribosomal small subunit assembly (GO:0000028)4.57224147
8DNA strand elongation involved in DNA replication (GO:0006271)4.50444507
9ATP synthesis coupled proton transport (GO:0015986)4.49975532
10energy coupled proton transport, down electrochemical gradient (GO:0015985)4.49975532
11DNA deamination (GO:0045006)4.46194480
12ribosomal large subunit biogenesis (GO:0042273)4.46019729
13telomere maintenance via semi-conservative replication (GO:0032201)4.42360609
14proteasome assembly (GO:0043248)4.42089309
15DNA strand elongation (GO:0022616)4.30195979
16mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.29008363
17DNA replication initiation (GO:0006270)4.26186304
18respiratory electron transport chain (GO:0022904)4.16031970
19ribonucleoprotein complex biogenesis (GO:0022613)4.10679780
20ribosome biogenesis (GO:0042254)4.08474577
21formation of translation preinitiation complex (GO:0001731)4.07031875
22ribosome assembly (GO:0042255)4.06618149
23DNA replication checkpoint (GO:0000076)4.06211744
24electron transport chain (GO:0022900)4.03822683
25oxidative phosphorylation (GO:0006119)4.01085595
26ribosomal small subunit biogenesis (GO:0042274)4.00892151
27protein targeting to mitochondrion (GO:0006626)3.92741531
28telomere maintenance via recombination (GO:0000722)3.92268050
29mitotic metaphase plate congression (GO:0007080)3.89605439
30viral transcription (GO:0019083)3.86816370
31translational termination (GO:0006415)3.83420847
32rRNA modification (GO:0000154)3.83313132
33CENP-A containing nucleosome assembly (GO:0034080)3.83295644
34protein deneddylation (GO:0000338)3.82905805
35IMP biosynthetic process (GO:0006188)3.82302385
36chromatin remodeling at centromere (GO:0031055)3.82078139
37positive regulation of ligase activity (GO:0051351)3.72856945
38establishment of viral latency (GO:0019043)3.72460893
39termination of RNA polymerase III transcription (GO:0006386)3.67427641
40transcription elongation from RNA polymerase III promoter (GO:0006385)3.67427641
41rRNA processing (GO:0006364)3.65348785
42spliceosomal snRNP assembly (GO:0000387)3.64941454
43mitotic recombination (GO:0006312)3.64640255
44establishment of protein localization to mitochondrion (GO:0072655)3.62049650
45telomere maintenance via telomere lengthening (GO:0010833)3.60219639
46negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.60194616
47protein localization to mitochondrion (GO:0070585)3.59209637
48regulation of ubiquitin-protein transferase activity (GO:0051438)3.58492613
49pseudouridine synthesis (GO:0001522)3.58199167
50mitochondrial respiratory chain complex I assembly (GO:0032981)3.55265237
51NADH dehydrogenase complex assembly (GO:0010257)3.55265237
52mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.55265237
53folic acid-containing compound biosynthetic process (GO:0009396)3.55256077
54rRNA metabolic process (GO:0016072)3.53241641
55translational elongation (GO:0006414)3.52689351
56translational initiation (GO:0006413)3.50553920
57mitochondrial respiratory chain complex assembly (GO:0033108)3.50408073
58protein neddylation (GO:0045116)3.50014183
59protein complex biogenesis (GO:0070271)3.48711491
60regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.46687525
61positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.45999719
62anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.45445468
63regulation of ligase activity (GO:0051340)3.44016141
64cellular component biogenesis (GO:0044085)3.41227575
65IMP metabolic process (GO:0046040)3.37405866
66folic acid metabolic process (GO:0046655)3.35954769
67DNA replication-dependent nucleosome assembly (GO:0006335)3.35863794
68DNA replication-dependent nucleosome organization (GO:0034723)3.35863794
69transcription-coupled nucleotide-excision repair (GO:0006283)3.35174415
70metaphase plate congression (GO:0051310)3.33684274
71DNA replication-independent nucleosome organization (GO:0034724)3.32989511
72DNA replication-independent nucleosome assembly (GO:0006336)3.32989511
73kinetochore organization (GO:0051383)3.32208381
74DNA unwinding involved in DNA replication (GO:0006268)3.30519990
75SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.30465502
76kinetochore assembly (GO:0051382)3.30006088
77transcription from mitochondrial promoter (GO:0006390)3.26819731
78nucleotide-excision repair, DNA gap filling (GO:0006297)3.26779730
79regulation of mitochondrial translation (GO:0070129)3.26537396
80respiratory chain complex IV assembly (GO:0008535)3.26394972
81negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.24849640
82negative regulation of ligase activity (GO:0051352)3.24849640
83* translation (GO:0006412)3.24603862
84cotranslational protein targeting to membrane (GO:0006613)3.22384118
85maturation of 5.8S rRNA (GO:0000460)3.22037587
86regulation of cellular amino acid metabolic process (GO:0006521)3.21759423
87RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.21151804
88tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.21151804
89DNA damage response, detection of DNA damage (GO:0042769)3.20528512
90transcription from RNA polymerase I promoter (GO:0006360)3.20427100
91protein targeting to ER (GO:0045047)3.19746770
92deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.18651023
93termination of RNA polymerase I transcription (GO:0006363)3.18561167
94DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.17509790
95regulation of cellular amine metabolic process (GO:0033238)3.17130636
967-methylguanosine mRNA capping (GO:0006370)3.16029918
97protein localization to kinetochore (GO:0034501)3.15717692
98transcription elongation from RNA polymerase I promoter (GO:0006362)3.15436529
99signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.15250455
100signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.15250455
101signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.15250455
102pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.14924628
103regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.14662486
104intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.14227149
105signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.14227149
106nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.12709526
107signal transduction involved in DNA damage checkpoint (GO:0072422)3.11953132
108signal transduction involved in DNA integrity checkpoint (GO:0072401)3.11953132
109negative regulation of protein ubiquitination (GO:0031397)3.11814820
110RNA capping (GO:0036260)3.10715124
1117-methylguanosine RNA capping (GO:0009452)3.10715124
112histone exchange (GO:0043486)3.10462768
113glycine metabolic process (GO:0006544)3.10079437
114mitochondrial RNA metabolic process (GO:0000959)3.08950976
115L-serine metabolic process (GO:0006563)3.07779747
116signal transduction involved in cell cycle checkpoint (GO:0072395)3.07662833
117mitotic nuclear envelope disassembly (GO:0007077)3.06540303
118G1/S transition of mitotic cell cycle (GO:0000082)3.06021701
119cell cycle G1/S phase transition (GO:0044843)3.06021701
120antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.05863480
121tricarboxylic acid cycle (GO:0006099)3.05782163
122pteridine-containing compound biosynthetic process (GO:0042559)3.05344111
123spliceosomal complex assembly (GO:0000245)3.05249629
124inner mitochondrial membrane organization (GO:0007007)3.05147750
125protein localization to endoplasmic reticulum (GO:0070972)3.04637291
126nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.04593164
127exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.03747523
128positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.03667887
129cellular protein complex disassembly (GO:0043624)3.01971528
130rRNA methylation (GO:0031167)3.01912189
131cullin deneddylation (GO:0010388)3.01709725
132establishment of protein localization to endoplasmic reticulum (GO:0072599)3.01274107
133establishment of integrated proviral latency (GO:0075713)3.01106491
134positive regulation of cell cycle arrest (GO:0071158)3.00323635
135peptidyl-histidine modification (GO:0018202)3.00157545
136regulation of nuclear cell cycle DNA replication (GO:0033262)2.98244328
137pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.96105158
138somatic diversification of immune receptors via somatic mutation (GO:0002566)2.95576549
139somatic hypermutation of immunoglobulin genes (GO:0016446)2.95576549
140DNA catabolic process, exonucleolytic (GO:0000738)2.95517149
141viral life cycle (GO:0019058)2.95247965
142L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.92581071
143establishment of chromosome localization (GO:0051303)2.91427917

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.49308647
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.54763766
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.91656400
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.58699958
5* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.37765304
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.36578156
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.35907581
8E2F4_17652178_ChIP-ChIP_JURKAT_Human3.32372114
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.16274870
10MYC_19079543_ChIP-ChIP_MESCs_Mouse3.10528614
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.09273438
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.01501458
13CREB1_15753290_ChIP-ChIP_HEK293T_Human3.00898719
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.79865096
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.77912384
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.68765212
17E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.64798125
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.63523465
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.55949730
20* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.38064913
21VDR_23849224_ChIP-Seq_CD4+_Human2.37893634
22XRN2_22483619_ChIP-Seq_HELA_Human2.31037287
23* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.27554410
24HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.20851058
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.18558301
26DCP1A_22483619_ChIP-Seq_HELA_Human2.15728026
27FOXP3_21729870_ChIP-Seq_TREG_Human2.10910922
28MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.98608850
29THAP11_20581084_ChIP-Seq_MESCs_Mouse1.98218592
30NANOG_18555785_ChIP-Seq_MESCs_Mouse1.91326719
31* GABP_19822575_ChIP-Seq_HepG2_Human1.88463134
32YY1_21170310_ChIP-Seq_MESCs_Mouse1.87434675
33POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.87377203
34SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.87128442
35MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.86195780
36CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.85933503
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85529112
38TTF2_22483619_ChIP-Seq_HELA_Human1.81274237
39SRF_21415370_ChIP-Seq_HL-1_Mouse1.80891686
40AR_21909140_ChIP-Seq_LNCAP_Human1.76347630
41* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.75369304
42* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.72094475
43ELK1_19687146_ChIP-ChIP_HELA_Human1.70094583
44* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.66413310
45E2F1_21310950_ChIP-Seq_MCF-7_Human1.65588201
46YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.61640510
47SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.60037887
48POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.57083286
49MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.52497498
50POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.48421718
51HOXB4_20404135_ChIP-ChIP_EML_Mouse1.45342395
52ZFX_18555785_ChIP-Seq_MESCs_Mouse1.44774315
53STAT3_1855785_ChIP-Seq_MESCs_Mouse1.44407471
54* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.42967469
55PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.40726530
56TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.38168221
57SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.36064592
58KDM5A_27292631_Chip-Seq_BREAST_Human1.34113060
59* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.30153113
60CIITA_25753668_ChIP-Seq_RAJI_Human1.29613247
61CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.27820673
62FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.25426983
63CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.23938280
64PADI4_21655091_ChIP-ChIP_MCF-7_Human1.20046866
65ERG_20887958_ChIP-Seq_HPC-7_Mouse1.19285230
66* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.17046859
67SOX2_18555785_ChIP-Seq_MESCs_Mouse1.16863901
68SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13820660
69BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12131828
70NOTCH1_21737748_ChIP-Seq_TLL_Human1.11146072
71KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.07145170
72RBPJ_22232070_ChIP-Seq_NCS_Mouse1.07038637
73* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.06442984
74MYC_18940864_ChIP-ChIP_HL60_Human1.05914026
75* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.05305604
76ELK1_22589737_ChIP-Seq_MCF10A_Human1.02301648
77ZNF263_19887448_ChIP-Seq_K562_Human1.01185243
78NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.99832997
79NANOG_16153702_ChIP-ChIP_HESCs_Human0.99294638
80TCF3_18692474_ChIP-Seq_MEFs_Mouse0.98719703
81E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.98418400
82* PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.98371365
83KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.98186898
84KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.98186898
85KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.98186898
86TFEB_21752829_ChIP-Seq_HELA_Human0.96724648
87NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.95713485
88SOX2_18692474_ChIP-Seq_MEFs_Mouse0.94880640
89* HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.93879537
90PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.93344253
91CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.93003402
92TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.91840679
93DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.90680216
94OCT4_18692474_ChIP-Seq_MEFs_Mouse0.89772027
95HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.88681624
96KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.87701145
97CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.87461105
98EGR1_23403033_ChIP-Seq_LIVER_Mouse0.83937874
99DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.83885423
100CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.82936483
101* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.82643131
102TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.82529596
103HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.81334772
104* SOX17_20123909_ChIP-Seq_XEN_Mouse0.80532477
105* SOX2_16153702_ChIP-ChIP_HESCs_Human0.79912115
106* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.78606194
107NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.78547236
108SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.78065412
109GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.76498907
110SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.76386160
111CTCF_18555785_ChIP-Seq_MESCs_Mouse0.75941103
112SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.75163202
113FOXP1_21924763_ChIP-Seq_HESCs_Human0.67954791

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.72827141
2MP0010094_abnormal_chromosome_stability4.51606037
3MP0004957_abnormal_blastocyst_morpholog4.48966509
4MP0003806_abnormal_nucleotide_metabolis4.36104494
5MP0003111_abnormal_nucleus_morphology4.33050386
6MP0008058_abnormal_DNA_repair3.82069892
7MP0003077_abnormal_cell_cycle3.78404633
8MP0008057_abnormal_DNA_replication3.73226598
9MP0008932_abnormal_embryonic_tissue2.70813344
10MP0003718_maternal_effect2.48664424
11MP0008007_abnormal_cellular_replicative2.45381870
12MP0003786_premature_aging2.22502321
13MP0003186_abnormal_redox_activity2.13364192
14MP0001529_abnormal_vocalization2.09045772
15MP0003123_paternal_imprinting2.07277479
16MP0001730_embryonic_growth_arrest2.06915302
17MP0000749_muscle_degeneration1.96692047
18MP0009379_abnormal_foot_pigmentation1.83743608
19MP0000372_irregular_coat_pigmentation1.79771223
20MP0006036_abnormal_mitochondrial_physio1.78673665
21MP0000350_abnormal_cell_proliferation1.77586533
22MP0002837_dystrophic_cardiac_calcinosis1.73298157
23MP0002396_abnormal_hematopoietic_system1.63771699
24MP0004215_abnormal_myocardial_fiber1.60603054
25MP0006035_abnormal_mitochondrial_morpho1.58132999
26MP0008877_abnormal_DNA_methylation1.55571509
27MP0009697_abnormal_copulation1.53109947
28MP0000751_myopathy1.51524540
29MP0004147_increased_porphyrin_level1.48271419
30MP0001672_abnormal_embryogenesis/_devel1.48265062
31MP0005380_embryogenesis_phenotype1.48265062
32MP0002132_abnormal_respiratory_system1.45509414
33MP0008789_abnormal_olfactory_epithelium1.45088405
34MP0003567_abnormal_fetal_cardiomyocyte1.45081642
35MP0001764_abnormal_homeostasis1.43700513
36MP0005085_abnormal_gallbladder_physiolo1.41459463
37MP0000490_abnormal_crypts_of1.40977022
38MP0001697_abnormal_embryo_size1.39643542
39MP0005360_urolithiasis1.38545247
40MP0006292_abnormal_olfactory_placode1.37586311
41MP0002080_prenatal_lethality1.33272083
42MP0004145_abnormal_muscle_electrophysio1.29804818
43MP0000313_abnormal_cell_death1.29177276
44MP0003984_embryonic_growth_retardation1.29030040
45MP0002088_abnormal_embryonic_growth/wei1.25956486
46MP0002139_abnormal_hepatobiliary_system1.25749938
47MP0003136_yellow_coat_color1.24872171
48MP0004133_heterotaxia1.23557918
49MP0005266_abnormal_metabolism1.23089106
50MP0002019_abnormal_tumor_incidence1.22262471
51MP0002938_white_spotting1.20631357
52MP0010352_gastrointestinal_tract_polyps1.20303382
53MP0010307_abnormal_tumor_latency1.19962599
54MP0003941_abnormal_skin_development1.19825450
55MP0005075_abnormal_melanosome_morpholog1.16341835
56MP0002210_abnormal_sex_determination1.15772093
57MP0009333_abnormal_splenocyte_physiolog1.13652086
58MP0000358_abnormal_cell_content/1.12141430
59MP0002160_abnormal_reproductive_system1.11339014
60MP0003950_abnormal_plasma_membrane1.10745654
61MP0002085_abnormal_embryonic_tissue1.10265226
62MP0004233_abnormal_muscle_weight1.09871588
63MP0001727_abnormal_embryo_implantation1.08432752
64MP0003315_abnormal_perineum_morphology1.06411679
65MP0001145_abnormal_male_reproductive1.03552043
66MP0005084_abnormal_gallbladder_morpholo1.03163689
67MP0002086_abnormal_extraembryonic_tissu1.02748914
68MP0001293_anophthalmia1.01758865
69MP0005365_abnormal_bile_salt1.01681031
70MP0003221_abnormal_cardiomyocyte_apopto1.00829117
71MP0003890_abnormal_embryonic-extraembry0.97252927
72MP0001853_heart_inflammation0.97089195
73MP0005389_reproductive_system_phenotype0.95819034
74MP0000747_muscle_weakness0.95496192
75MP0002090_abnormal_vision0.93788474
76MP0006072_abnormal_retinal_apoptosis0.93466011
77MP0004036_abnormal_muscle_relaxation0.93412110
78MP0009840_abnormal_foam_cell0.93342272
79MP0004197_abnormal_fetal_growth/weight/0.92988671
80MP0002102_abnormal_ear_morphology0.90743990
81MP0002084_abnormal_developmental_patter0.88292962
82MP0000653_abnormal_sex_gland0.86588282
83MP0001929_abnormal_gametogenesis0.86531011
84MP0003937_abnormal_limbs/digits/tail_de0.86434647
85MP0003646_muscle_fatigue0.82571840
86MP0005332_abnormal_amino_acid0.82513060
87MP0000647_abnormal_sebaceous_gland0.81358470
88MP0001119_abnormal_female_reproductive0.80217088
89MP0005408_hypopigmentation0.80154754
90MP0003137_abnormal_impulse_conducting0.80140251
91MP0002106_abnormal_muscle_physiology0.79737707
92MP0002972_abnormal_cardiac_muscle0.79557892
93MP0002163_abnormal_gland_morphology0.76203931
94MP0005499_abnormal_olfactory_system0.75324588
95MP0005394_taste/olfaction_phenotype0.75324588
96MP0005395_other_phenotype0.74074636
97MP0002736_abnormal_nociception_after0.73108451
98MP0005319_abnormal_enzyme/_coenzyme0.71944216
99MP0005376_homeostasis/metabolism_phenot0.71752960
100MP0010030_abnormal_orbit_morphology0.70574308
101MP0003763_abnormal_thymus_physiology0.70491338
102MP0001986_abnormal_taste_sensitivity0.70218970
103MP0001919_abnormal_reproductive_system0.69954415
104MP0002722_abnormal_immune_system0.69861660
105MP0000689_abnormal_spleen_morphology0.69611506
106MP0005501_abnormal_skin_physiology0.69315483
107MP0002234_abnormal_pharynx_morphology0.68935811
108MP0000750_abnormal_muscle_regeneration0.68677777
109MP0004084_abnormal_cardiac_muscle0.68304051
110MP0004381_abnormal_hair_follicle0.67638646
111MP0001905_abnormal_dopamine_level0.67626318
112MP0000858_altered_metastatic_potential0.66887830
113MP0000703_abnormal_thymus_morphology0.66727857
114MP0002233_abnormal_nose_morphology0.66308915
115MP0004087_abnormal_muscle_fiber0.65775586
116MP0002269_muscular_atrophy0.65019031
117MP0008995_early_reproductive_senescence0.64926459
118MP0008260_abnormal_autophagy0.64847253
119MP0005670_abnormal_white_adipose0.64841719
120MP0003011_delayed_dark_adaptation0.64549781
121MP0008775_abnormal_heart_ventricle0.64257229
122MP0000598_abnormal_liver_morphology0.62584696
123MP0001346_abnormal_lacrimal_gland0.62124303
124MP0005384_cellular_phenotype0.62023571
125MP0009672_abnormal_birth_weight0.61585302
126MP0008875_abnormal_xenobiotic_pharmacok0.61156794
127MP0005369_muscle_phenotype0.60381892
128MP0005385_cardiovascular_system_phenoty0.59667245
129MP0001544_abnormal_cardiovascular_syste0.59667245
130MP0000759_abnormal_skeletal_muscle0.59591291
131MP0005451_abnormal_body_composition0.58827600
132MP0004019_abnormal_vitamin_homeostasis0.58495799
133MP0003119_abnormal_digestive_system0.57169274
134MP0002111_abnormal_tail_morphology0.54385976
135MP0005330_cardiomyopathy0.53429252
136MP0001661_extended_life_span0.53401991
137MP0001286_abnormal_eye_development0.53023930
138MP0002398_abnormal_bone_marrow0.53014768
139MP0002429_abnormal_blood_cell0.52967226
140MP0002277_abnormal_respiratory_mucosa0.52843285
141MP0005397_hematopoietic_system_phenotyp0.52794936

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.72128042
2Reticulocytopenia (HP:0001896)4.37466612
3Breast hypoplasia (HP:0003187)3.94215090
4Oral leukoplakia (HP:0002745)3.77732454
5Abnormality of cells of the erythroid lineage (HP:0012130)3.75347446
6Abnormal number of erythroid precursors (HP:0012131)3.58136919
7Chromsome breakage (HP:0040012)3.46430722
8Chromosomal breakage induced by crosslinking agents (HP:0003221)3.42493023
9Hepatic necrosis (HP:0002605)3.26478141
10Hepatocellular necrosis (HP:0001404)3.26199823
11Cerebral hypomyelination (HP:0006808)3.22297951
12Decreased activity of mitochondrial respiratory chain (HP:0008972)3.22118703
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.22118703
14Macrocytic anemia (HP:0001972)3.19675137
15Renal Fanconi syndrome (HP:0001994)3.18383646
16Increased serum lactate (HP:0002151)3.15417175
17Abnormality of pyrimidine metabolism (HP:0004353)3.15317584
18Rough bone trabeculation (HP:0100670)3.14045440
19Acute necrotizing encephalopathy (HP:0006965)3.11822309
20Increased CSF lactate (HP:0002490)3.10845087
21Increased muscle lipid content (HP:0009058)3.08438321
22Nemaline bodies (HP:0003798)3.05160813
23Mitochondrial inheritance (HP:0001427)3.03054446
24Abnormality of the preputium (HP:0100587)3.00885919
25Abnormal mitochondria in muscle tissue (HP:0008316)2.94358299
26Microvesicular hepatic steatosis (HP:0001414)2.86573235
27Acute encephalopathy (HP:0006846)2.83161044
28Colon cancer (HP:0003003)2.80710346
29Aplastic anemia (HP:0001915)2.79930112
30Muscle fiber inclusion bodies (HP:0100299)2.79254433
31Meckel diverticulum (HP:0002245)2.79225412
32Increased serum pyruvate (HP:0003542)2.78942712
33Abnormality of glycolysis (HP:0004366)2.78942712
34Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.78042385
353-Methylglutaconic aciduria (HP:0003535)2.76913667
36Carpal bone hypoplasia (HP:0001498)2.73770176
37Abnormality of chromosome stability (HP:0003220)2.71115571
38Absent thumb (HP:0009777)2.71112961
39Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.70637096
40Leukodystrophy (HP:0002415)2.66639951
41Cerebral edema (HP:0002181)2.64226986
42Impulsivity (HP:0100710)2.64123350
43Abnormality of the ileum (HP:0001549)2.63708527
44Pallor (HP:0000980)2.60000400
45Patellar aplasia (HP:0006443)2.59556730
46Hyperglycinemia (HP:0002154)2.58197395
47Multiple enchondromatosis (HP:0005701)2.57858272
48Exercise-induced muscle cramps (HP:0003710)2.57328302
49Absent radius (HP:0003974)2.56360994
50Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.52505334
51Aplasia/Hypoplasia of the sacrum (HP:0008517)2.51227719
52Increased hepatocellular lipid droplets (HP:0006565)2.49319048
53Lactic acidosis (HP:0003128)2.48522332
54Aplasia/Hypoplasia of the uvula (HP:0010293)2.47472270
55Respiratory difficulties (HP:0002880)2.42357077
56Aplasia/Hypoplasia of the patella (HP:0006498)2.42068022
57Agnosia (HP:0010524)2.41589749
58Selective tooth agenesis (HP:0001592)2.40335249
59Lipid accumulation in hepatocytes (HP:0006561)2.39686753
60Degeneration of anterior horn cells (HP:0002398)2.37164868
61Abnormality of the anterior horn cell (HP:0006802)2.37164868
62Optic disc pallor (HP:0000543)2.37120301
63Duplicated collecting system (HP:0000081)2.36711295
64Type I transferrin isoform profile (HP:0003642)2.36257929
65Absent forearm bone (HP:0003953)2.35341704
66Aplasia involving forearm bones (HP:0009822)2.35341704
67Bone marrow hypocellularity (HP:0005528)2.34705834
68Premature graying of hair (HP:0002216)2.34656536
69Abnormal protein glycosylation (HP:0012346)2.32959216
70Abnormal glycosylation (HP:0012345)2.32959216
71Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.32959216
72Abnormal protein N-linked glycosylation (HP:0012347)2.32959216
73Progressive macrocephaly (HP:0004481)2.31749618
74Abnormal trabecular bone morphology (HP:0100671)2.31204512
75Hyperglycinuria (HP:0003108)2.30927464
76Medulloblastoma (HP:0002885)2.30440408
77Premature ovarian failure (HP:0008209)2.30195992
78Exercise intolerance (HP:0003546)2.29785520
79Hypobetalipoproteinemia (HP:0003563)2.29558560
80Microretrognathia (HP:0000308)2.27325184
81Methylmalonic aciduria (HP:0012120)2.26137849
82Exertional dyspnea (HP:0002875)2.25699714
83Cellular immunodeficiency (HP:0005374)2.25582649
84Megaloblastic anemia (HP:0001889)2.24918036
85CNS demyelination (HP:0007305)2.24491783
86Pancytopenia (HP:0001876)2.24422021
87Abnormality of serum amino acid levels (HP:0003112)2.24215249
88Trismus (HP:0000211)2.24100754
89Abnormality of methionine metabolism (HP:0010901)2.23493060
90Horseshoe kidney (HP:0000085)2.21777363
91Lethargy (HP:0001254)2.20907295
92Nausea (HP:0002018)2.19631202
93Methylmalonic acidemia (HP:0002912)2.17531392
94Respiratory failure (HP:0002878)2.15829240
95Secondary amenorrhea (HP:0000869)2.14696148
96Triphalangeal thumb (HP:0001199)2.14685005
97Ependymoma (HP:0002888)2.14675025
98Ragged-red muscle fibers (HP:0003200)2.13189768
99Sparse eyelashes (HP:0000653)2.10403740
100Emotional lability (HP:0000712)2.09703796
101Supernumerary spleens (HP:0009799)2.09371532
102Small intestinal stenosis (HP:0012848)2.08408730
103Duodenal stenosis (HP:0100867)2.08408730
104Palpitations (HP:0001962)2.06210226
105Abnormality of the renal collecting system (HP:0004742)2.05343655
106Generalized aminoaciduria (HP:0002909)2.04984705
107Neoplasm of the pancreas (HP:0002894)2.04089390
108Abnormality of the labia minora (HP:0012880)2.03251576
109Increased intramyocellular lipid droplets (HP:0012240)2.02544995
110Progressive external ophthalmoplegia (HP:0000590)2.02384787
111Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.02143521
112Abnormality of alanine metabolism (HP:0010916)2.02143521
113Hyperalaninemia (HP:0003348)2.02143521
114Rhabdomyolysis (HP:0003201)2.00257836
115Abnormality of glycine metabolism (HP:0010895)1.98942459
116Abnormality of serine family amino acid metabolism (HP:0010894)1.98942459
117Ureteral duplication (HP:0000073)1.97522019
118Abnormality of monocarboxylic acid metabolism (HP:0010996)1.97322504
119Myelodysplasia (HP:0002863)1.97056629
120Rhabdomyosarcoma (HP:0002859)1.96840073
121X-linked dominant inheritance (HP:0001423)1.96256112
122Gout (HP:0001997)1.95104234
123Progressive muscle weakness (HP:0003323)1.95009042
124Amniotic constriction ring (HP:0009775)1.94612756
125Abnormality of placental membranes (HP:0011409)1.94612756
126Reduced antithrombin III activity (HP:0001976)1.93852197
127Abnormal lung lobation (HP:0002101)1.90691888
128Abnormality of dicarboxylic acid metabolism (HP:0010995)1.86441142
129Dicarboxylic aciduria (HP:0003215)1.86441142
130Aplasia/hypoplasia of the uterus (HP:0008684)1.82190789
131Type 2 muscle fiber atrophy (HP:0003554)1.80740666
132Posterior subcapsular cataract (HP:0007787)1.79554657
133Abnormality of aspartate family amino acid metabolism (HP:0010899)1.78979820
134Postnatal microcephaly (HP:0005484)1.78190457
135Testicular atrophy (HP:0000029)1.77820709
136Muscle fiber atrophy (HP:0100295)1.74265125
137CNS hypomyelination (HP:0003429)1.74148302
138Glycosuria (HP:0003076)1.74128382
139Abnormality of urine glucose concentration (HP:0011016)1.74128382
140Neoplasm of the adrenal gland (HP:0100631)1.73576450

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.82051391
2WEE14.35102300
3EIF2AK14.14408940
4VRK23.80772154
5STK163.28953969
6CDC72.94439651
7NME22.79478865
8SRPK12.75944772
9PLK42.63529025
10EIF2AK32.42680151
11ACVR1B2.28388158
12TLK12.23065655
13TTK2.22506364
14TSSK62.16662003
15NEK12.11412908
16VRK12.04356794
17BCKDK2.01465353
18ZAK1.94720359
19PLK11.86255824
20EPHA21.83931322
21TRIM281.79819572
22BRSK21.76848730
23NEK21.73988744
24TESK21.69442688
25MKNK11.63461395
26DYRK31.56516396
27NUAK11.56073292
28MKNK21.49785399
29AURKB1.47368649
30CDK71.44008034
31PLK31.42404237
32ATR1.40364257
33PBK1.38989614
34RPS6KB21.33198623
35CSNK1G31.28718626
36MAP3K121.28319683
37AURKA1.28132306
38CSNK1G11.19049429
39EIF2AK21.18530849
40CHEK21.15231027
41IRAK31.15112089
42NME11.14937754
43CDK191.08262340
44TAF11.07985470
45MAP3K81.06406946
46RPS6KA41.05754906
47PIM21.04963290
48PASK1.03275121
49CSNK1G21.02542954
50BRSK11.02520481
51CCNB11.02357451
52STK41.00793126
53KDR0.98330605
54MAP3K110.96535414
55CDK40.95129762
56CSNK1A1L0.94066181
57FLT30.89363878
58CHEK10.89150686
59BRAF0.89085698
60STK38L0.86968133
61DAPK10.86592942
62MAP4K20.86282805
63PDK30.85578138
64PDK40.85578138
65ARAF0.84389235
66AKT30.83627485
67CSNK2A10.79928650
68CSNK2A20.79120697
69ERBB30.76789614
70PIM10.75585313
71TAOK20.75408933
72BCR0.73960249
73PNCK0.72319825
74TGFBR10.71948346
75WNK30.71383179
76OBSCN0.69395387
77ATM0.69305985
78PAK40.68780313
79MAP2K70.66950664
80PRKCI0.64878561
81RPS6KA50.62877852
82CDK80.62714513
83MST1R0.62580433
84PHKG20.61501816
85PHKG10.61501816
86PDK20.61322487
87CDK20.60656179
88MST40.57531567
89PAK10.56458052
90ERBB40.54188974
91ILK0.53999956
92PINK10.53667792
93MAPKAPK30.52101963
94STK100.51979509
95DYRK20.51062297
96TESK10.49840437
97ABL20.49400031
98IRAK40.44513721
99CDK10.44281296
100MAP2K30.43550723
101MAP2K60.42298262
102BRD40.41947792
103TIE10.41154921
104DAPK30.39795334
105PLK20.39617718
106MELK0.37157035
107CLK10.36023249
108SCYL20.34893855
109MUSK0.33309862
110CDK140.32229826
111CSNK1E0.32065373
112CAMK2G0.31021503
113MAPKAPK50.30948484
114ALK0.29468302
115AKT20.28957730
116NEK90.28316071
117CDK180.28191109
118CSNK1A10.27898059
119MAP3K50.27660297
120GRK10.26641604
121CDK11A0.26318988
122YES10.26161926
123TEC0.25096878
124TXK0.23122510
125LIMK10.21698426
126PRKDC0.20943199
127IKBKB0.20163318
128MAP3K30.19813969
129BLK0.17892603
130MYLK0.16395791
131BMPR1B0.16163076
132MARK30.15619351
133CDK120.14036863

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.16414173
2Proteasome_Homo sapiens_hsa030503.80700280
3* Ribosome_Homo sapiens_hsa030103.70335019
4Mismatch repair_Homo sapiens_hsa034303.68584214
5RNA polymerase_Homo sapiens_hsa030203.47229265
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.39307879
7One carbon pool by folate_Homo sapiens_hsa006702.71173818
8Homologous recombination_Homo sapiens_hsa034402.69445808
9Spliceosome_Homo sapiens_hsa030402.68293656
10Pyrimidine metabolism_Homo sapiens_hsa002402.57530714
11RNA transport_Homo sapiens_hsa030132.49645081
12Nucleotide excision repair_Homo sapiens_hsa034202.49323610
13Base excision repair_Homo sapiens_hsa034102.42870241
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.23780348
15Fanconi anemia pathway_Homo sapiens_hsa034601.98081052
16Cell cycle_Homo sapiens_hsa041101.75515941
17Non-homologous end-joining_Homo sapiens_hsa034501.75250601
18Basal transcription factors_Homo sapiens_hsa030221.61265095
19Oxidative phosphorylation_Homo sapiens_hsa001901.51306017
20RNA degradation_Homo sapiens_hsa030181.49342220
21Parkinsons disease_Homo sapiens_hsa050121.48924722
22Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.48726668
23Folate biosynthesis_Homo sapiens_hsa007901.42994939
24Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.40117472
25Purine metabolism_Homo sapiens_hsa002301.39432575
26Cysteine and methionine metabolism_Homo sapiens_hsa002701.37058505
272-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.35369950
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.34835266
29Huntingtons disease_Homo sapiens_hsa050161.30059364
30Sulfur relay system_Homo sapiens_hsa041221.28848427
31Drug metabolism - other enzymes_Homo sapiens_hsa009831.28562326
32Vitamin B6 metabolism_Homo sapiens_hsa007501.28238349
33Biosynthesis of amino acids_Homo sapiens_hsa012301.27783565
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.25664512
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.24677401
36Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.17116735
37Pentose phosphate pathway_Homo sapiens_hsa000301.13471883
38Carbon metabolism_Homo sapiens_hsa012001.12837590
39Cyanoamino acid metabolism_Homo sapiens_hsa004601.12086736
40Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.09900512
41Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.05553947
42Steroid biosynthesis_Homo sapiens_hsa001001.04814460
43Sulfur metabolism_Homo sapiens_hsa009201.04420395
44Selenocompound metabolism_Homo sapiens_hsa004501.04135651
45p53 signaling pathway_Homo sapiens_hsa041151.02365769
46Protein export_Homo sapiens_hsa030601.00390200
47mRNA surveillance pathway_Homo sapiens_hsa030150.98818893
48Glutathione metabolism_Homo sapiens_hsa004800.90720836
49Systemic lupus erythematosus_Homo sapiens_hsa053220.90134726
50Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.88813951
51Epstein-Barr virus infection_Homo sapiens_hsa051690.85709357
52Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.83228518
53Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.74461943
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.73139253
55Alzheimers disease_Homo sapiens_hsa050100.72183512
56Arginine and proline metabolism_Homo sapiens_hsa003300.67813985
57Metabolic pathways_Homo sapiens_hsa011000.65735824
58Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.65424326
59Pyruvate metabolism_Homo sapiens_hsa006200.62963286
60Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.61937919
61Fructose and mannose metabolism_Homo sapiens_hsa000510.61232767
62Propanoate metabolism_Homo sapiens_hsa006400.60825278
63beta-Alanine metabolism_Homo sapiens_hsa004100.56523444
64Peroxisome_Homo sapiens_hsa041460.55801709
65Primary bile acid biosynthesis_Homo sapiens_hsa001200.52913656
66Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.51846156
67Fatty acid degradation_Homo sapiens_hsa000710.51681263
68Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50271461
69Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.49764236
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.49297915
71Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.49105795
72Phenylalanine metabolism_Homo sapiens_hsa003600.48151018
73Tyrosine metabolism_Homo sapiens_hsa003500.46856978
74Herpes simplex infection_Homo sapiens_hsa051680.46390621
75N-Glycan biosynthesis_Homo sapiens_hsa005100.45756529
76Tryptophan metabolism_Homo sapiens_hsa003800.43835915
77Antigen processing and presentation_Homo sapiens_hsa046120.42876643
78Retinol metabolism_Homo sapiens_hsa008300.42411177
79Collecting duct acid secretion_Homo sapiens_hsa049660.42111513
80Galactose metabolism_Homo sapiens_hsa000520.41602345
81Fatty acid elongation_Homo sapiens_hsa000620.41555867
82Butanoate metabolism_Homo sapiens_hsa006500.40831631
83Chemical carcinogenesis_Homo sapiens_hsa052040.38335336
84Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.36600934
85Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.35337977
86Vitamin digestion and absorption_Homo sapiens_hsa049770.34953790
87Viral carcinogenesis_Homo sapiens_hsa052030.34060665
88Arachidonic acid metabolism_Homo sapiens_hsa005900.33235583
89Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.33026871
90Regulation of autophagy_Homo sapiens_hsa041400.32007005
91Arginine biosynthesis_Homo sapiens_hsa002200.31779556
92Steroid hormone biosynthesis_Homo sapiens_hsa001400.30172612
93Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.29117398
94Oocyte meiosis_Homo sapiens_hsa041140.28883505
95Histidine metabolism_Homo sapiens_hsa003400.28061508
96Cardiac muscle contraction_Homo sapiens_hsa042600.27161909
97Vibrio cholerae infection_Homo sapiens_hsa051100.26337340
98Legionellosis_Homo sapiens_hsa051340.26011149
99Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.25782140
100Linoleic acid metabolism_Homo sapiens_hsa005910.25585772
101Fat digestion and absorption_Homo sapiens_hsa049750.22524257
102Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.16736727
103Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.15019093
104HTLV-I infection_Homo sapiens_hsa051660.14715928
105Primary immunodeficiency_Homo sapiens_hsa053400.14505700
106Thyroid cancer_Homo sapiens_hsa052160.14013167
107Fatty acid metabolism_Homo sapiens_hsa012120.13775492
108Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.13425441
109Caffeine metabolism_Homo sapiens_hsa002320.11430229
110Nitrogen metabolism_Homo sapiens_hsa009100.05133536
111Starch and sucrose metabolism_Homo sapiens_hsa005000.04155487
112Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.02593779

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