Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 4.87015399 |
2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.49032058 |
3 | chaperone-mediated protein transport (GO:0072321) | 4.33495045 |
4 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.32628448 |
5 | maturation of SSU-rRNA (GO:0030490) | 4.28990281 |
6 | viral transcription (GO:0019083) | 4.20215735 |
7 | translational termination (GO:0006415) | 4.19241644 |
8 | purine nucleobase biosynthetic process (GO:0009113) | 4.10132194 |
9 | nucleobase biosynthetic process (GO:0046112) | 4.08090015 |
10 | ATP synthesis coupled proton transport (GO:0015986) | 4.07176725 |
11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.07176725 |
12 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.95256731 |
13 | ribosomal small subunit biogenesis (GO:0042274) | 3.86118643 |
14 | oxidative phosphorylation (GO:0006119) | 3.85870512 |
15 | establishment of integrated proviral latency (GO:0075713) | 3.81481610 |
16 | translational elongation (GO:0006414) | 3.80703223 |
17 | formation of translation preinitiation complex (GO:0001731) | 3.79636204 |
18 | ribosomal large subunit biogenesis (GO:0042273) | 3.79541521 |
19 | DNA deamination (GO:0045006) | 3.74897022 |
20 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.70927942 |
21 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.66640082 |
22 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.65015177 |
23 | cotranslational protein targeting to membrane (GO:0006613) | 3.61883263 |
24 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.61362309 |
25 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.60995079 |
26 | protein targeting to ER (GO:0045047) | 3.59193733 |
27 | translational initiation (GO:0006413) | 3.58240563 |
28 | proteasome assembly (GO:0043248) | 3.55633539 |
29 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.52423685 |
30 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.51597626 |
31 | DNA strand elongation (GO:0022616) | 3.50159803 |
32 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.49934575 |
33 | establishment of viral latency (GO:0019043) | 3.47705954 |
34 | protein targeting to mitochondrion (GO:0006626) | 3.47368874 |
35 | deoxyribonucleotide catabolic process (GO:0009264) | 3.45480400 |
36 | protein localization to endoplasmic reticulum (GO:0070972) | 3.44853052 |
37 | deoxyribose phosphate catabolic process (GO:0046386) | 3.44523354 |
38 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.41663460 |
39 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.39239821 |
40 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.38247828 |
41 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.38224110 |
42 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.37884937 |
43 | respiratory electron transport chain (GO:0022904) | 3.37551001 |
44 | glycine metabolic process (GO:0006544) | 3.36875604 |
45 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.36559475 |
46 | NADH dehydrogenase complex assembly (GO:0010257) | 3.36559475 |
47 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.36559475 |
48 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.36099856 |
49 | DNA replication checkpoint (GO:0000076) | 3.34971942 |
50 | electron transport chain (GO:0022900) | 3.34622930 |
51 | * translation (GO:0006412) | 3.33871770 |
52 | DNA replication initiation (GO:0006270) | 3.33345765 |
53 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.32831739 |
54 | maturation of 5.8S rRNA (GO:0000460) | 3.30927142 |
55 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.30344378 |
56 | IMP biosynthetic process (GO:0006188) | 3.29372951 |
57 | cellular protein complex disassembly (GO:0043624) | 3.27470184 |
58 | rRNA modification (GO:0000154) | 3.27282137 |
59 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.26187321 |
60 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.26187321 |
61 | negative regulation of ligase activity (GO:0051352) | 3.25916043 |
62 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.25916043 |
63 | base-excision repair, AP site formation (GO:0006285) | 3.25138567 |
64 | tricarboxylic acid cycle (GO:0006099) | 3.23320617 |
65 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.21642368 |
66 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.21642368 |
67 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.21642368 |
68 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.20894373 |
69 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.20701957 |
70 | regulation of mitochondrial translation (GO:0070129) | 3.19574526 |
71 | telomere maintenance via recombination (GO:0000722) | 3.19464133 |
72 | establishment of protein localization to mitochondrion (GO:0072655) | 3.19333294 |
73 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.17486053 |
74 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.16989371 |
75 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.15853590 |
76 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.15853590 |
77 | CENP-A containing nucleosome assembly (GO:0034080) | 3.15727169 |
78 | cellular component biogenesis (GO:0044085) | 3.14499639 |
79 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.14371961 |
80 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.13528160 |
81 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.13528160 |
82 | purine nucleotide salvage (GO:0032261) | 3.12527895 |
83 | mitotic metaphase plate congression (GO:0007080) | 3.12083273 |
84 | viral life cycle (GO:0019058) | 3.11518233 |
85 | protein complex biogenesis (GO:0070271) | 3.11442499 |
86 | chromatin remodeling at centromere (GO:0031055) | 3.10828812 |
87 | ribosome biogenesis (GO:0042254) | 3.10574310 |
88 | protein localization to mitochondrion (GO:0070585) | 3.10184767 |
89 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.10038341 |
90 | iron-sulfur cluster assembly (GO:0016226) | 3.09395641 |
91 | metallo-sulfur cluster assembly (GO:0031163) | 3.09395641 |
92 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.07534920 |
93 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.06905570 |
94 | aerobic respiration (GO:0009060) | 3.06550214 |
95 | regulation of ligase activity (GO:0051340) | 3.06360979 |
96 | cullin deneddylation (GO:0010388) | 3.06070986 |
97 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.05691643 |
98 | DNA ligation (GO:0006266) | 3.03453575 |
99 | protein deneddylation (GO:0000338) | 3.01563278 |
100 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.00003274 |
101 | rRNA processing (GO:0006364) | 2.99951858 |
102 | IMP metabolic process (GO:0046040) | 2.99900848 |
103 | lysine catabolic process (GO:0006554) | 2.99421155 |
104 | lysine metabolic process (GO:0006553) | 2.99421155 |
105 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.98360982 |
106 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.98094649 |
107 | viral mRNA export from host cell nucleus (GO:0046784) | 2.98073913 |
108 | spliceosomal snRNP assembly (GO:0000387) | 2.97650882 |
109 | folic acid metabolic process (GO:0046655) | 2.94691995 |
110 | amino acid salvage (GO:0043102) | 2.92652163 |
111 | L-methionine salvage (GO:0071267) | 2.92652163 |
112 | L-methionine biosynthetic process (GO:0071265) | 2.92652163 |
113 | pseudouridine synthesis (GO:0001522) | 2.91568019 |
114 | mitotic recombination (GO:0006312) | 2.89495425 |
115 | ribosome assembly (GO:0042255) | 2.88523735 |
116 | rRNA metabolic process (GO:0016072) | 2.86444404 |
117 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.86030015 |
118 | positive regulation of ligase activity (GO:0051351) | 2.85675688 |
119 | L-phenylalanine metabolic process (GO:0006558) | 2.85113718 |
120 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.85113718 |
121 | NADH metabolic process (GO:0006734) | 2.80866665 |
122 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.80209532 |
123 | termination of RNA polymerase III transcription (GO:0006386) | 2.80209532 |
124 | serine family amino acid biosynthetic process (GO:0009070) | 2.79097948 |
125 | cell cycle G1/S phase transition (GO:0044843) | 2.78009487 |
126 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.78009487 |
127 | telomere maintenance via telomere lengthening (GO:0010833) | 2.77299105 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.74048701 |
2 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.39566469 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.36078708 |
4 | * KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.89893978 |
5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.50117767 |
6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.38934931 |
7 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.36577394 |
8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.20924174 |
9 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.10387387 |
10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.06266998 |
11 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.81387556 |
12 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.80669661 |
13 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.79323551 |
14 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.67759488 |
15 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.55512712 |
16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.51461265 |
17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.37471759 |
18 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.35886038 |
19 | * PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.35047293 |
20 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.28954882 |
21 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.28282009 |
22 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.28168386 |
23 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.26801202 |
24 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.26797949 |
25 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.25809159 |
26 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.25515867 |
27 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.22142070 |
28 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.18811111 |
29 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.11674342 |
30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.06421446 |
31 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 2.03907965 |
32 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.03586464 |
33 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.99461005 |
34 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.92985224 |
35 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.91005827 |
36 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.88110126 |
37 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.86334738 |
38 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.77162741 |
39 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.75299127 |
40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.74796774 |
41 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.69581099 |
42 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.67453872 |
43 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.65801797 |
44 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.64957095 |
45 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.64577729 |
46 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.61444628 |
47 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.57855729 |
48 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.55120220 |
49 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.54978460 |
50 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.54420502 |
51 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.52387504 |
52 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.50683625 |
53 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.50168550 |
54 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.49787495 |
55 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.48983418 |
56 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.47640905 |
57 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.47433596 |
58 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.41309492 |
59 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.40332202 |
60 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.39694586 |
61 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.39453048 |
62 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.36887575 |
63 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.36160727 |
64 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.35039638 |
65 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.33701461 |
66 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.32975156 |
67 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.31926444 |
68 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.25796201 |
69 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.25554038 |
70 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19434075 |
71 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.19194693 |
72 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.15671099 |
73 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.14522808 |
74 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.08645219 |
75 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.08448269 |
76 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.07565133 |
77 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.07228638 |
78 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.07163630 |
79 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.07066601 |
80 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.07061632 |
81 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.04636794 |
82 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.04102277 |
83 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.02137638 |
84 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.00805171 |
85 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.98816107 |
86 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.96422258 |
87 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.93753600 |
88 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.93408172 |
89 | * ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.93185894 |
90 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.91560090 |
91 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.91547766 |
92 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.91383001 |
93 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.90953807 |
94 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.90231425 |
95 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.89347567 |
96 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.87261849 |
97 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.85850813 |
98 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.84387449 |
99 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.84385549 |
100 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.82253258 |
101 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.80465830 |
102 | * MYB_26560356_Chip-Seq_TH2_Human | 0.80203241 |
103 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.78726295 |
104 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.77586641 |
105 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.77529930 |
106 | MYC_22102868_ChIP-Seq_BL_Human | 0.77028011 |
107 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.75995907 |
108 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.74950170 |
109 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.73078275 |
110 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.71281711 |
111 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.69888163 |
112 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.67944426 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003806_abnormal_nucleotide_metabolis | 4.39045306 |
2 | MP0003693_abnormal_embryo_hatching | 4.18435637 |
3 | MP0005360_urolithiasis | 3.65030609 |
4 | MP0002139_abnormal_hepatobiliary_system | 3.48203141 |
5 | MP0005085_abnormal_gallbladder_physiolo | 3.45780091 |
6 | MP0004957_abnormal_blastocyst_morpholog | 3.38383296 |
7 | MP0006036_abnormal_mitochondrial_physio | 3.17856484 |
8 | MP0010094_abnormal_chromosome_stability | 2.95922262 |
9 | MP0003186_abnormal_redox_activity | 2.81786083 |
10 | MP0005365_abnormal_bile_salt | 2.69016434 |
11 | MP0003111_abnormal_nucleus_morphology | 2.50252323 |
12 | MP0003077_abnormal_cell_cycle | 2.47942300 |
13 | MP0005332_abnormal_amino_acid | 2.42934897 |
14 | MP0008875_abnormal_xenobiotic_pharmacok | 2.22296846 |
15 | MP0003646_muscle_fatigue | 2.15829284 |
16 | MP0006054_spinal_hemorrhage | 2.14567726 |
17 | MP0008057_abnormal_DNA_replication | 2.13246332 |
18 | MP0006035_abnormal_mitochondrial_morpho | 2.07460945 |
19 | MP0006292_abnormal_olfactory_placode | 2.02414656 |
20 | MP0000372_irregular_coat_pigmentation | 2.01603815 |
21 | MP0005075_abnormal_melanosome_morpholog | 1.94462725 |
22 | MP0003221_abnormal_cardiomyocyte_apopto | 1.93905904 |
23 | MP0003656_abnormal_erythrocyte_physiolo | 1.91149056 |
24 | MP0008058_abnormal_DNA_repair | 1.85831901 |
25 | MP0009379_abnormal_foot_pigmentation | 1.81459917 |
26 | MP0008932_abnormal_embryonic_tissue | 1.79444974 |
27 | MP0001835_abnormal_antigen_presentation | 1.79020826 |
28 | MP0005319_abnormal_enzyme/_coenzyme | 1.67237131 |
29 | MP0003123_paternal_imprinting | 1.63831029 |
30 | MP0001764_abnormal_homeostasis | 1.63503083 |
31 | MP0005083_abnormal_biliary_tract | 1.61900374 |
32 | MP0004084_abnormal_cardiac_muscle | 1.58846181 |
33 | MP0002396_abnormal_hematopoietic_system | 1.57197149 |
34 | MP0008007_abnormal_cellular_replicative | 1.55416357 |
35 | MP0003567_abnormal_fetal_cardiomyocyte | 1.47595105 |
36 | MP0005671_abnormal_response_to | 1.47371599 |
37 | MP0001730_embryonic_growth_arrest | 1.46822745 |
38 | MP0005330_cardiomyopathy | 1.46427864 |
39 | MP0002837_dystrophic_cardiac_calcinosis | 1.45833394 |
40 | MP0003718_maternal_effect | 1.45139084 |
41 | MP0002822_catalepsy | 1.44867367 |
42 | MP0009697_abnormal_copulation | 1.43696302 |
43 | MP0005451_abnormal_body_composition | 1.43508021 |
44 | MP0000749_muscle_degeneration | 1.41152485 |
45 | MP0009840_abnormal_foam_cell | 1.40539337 |
46 | MP0002148_abnormal_hypersensitivity_rea | 1.36537164 |
47 | MP0009278_abnormal_bone_marrow | 1.29139840 |
48 | MP0003252_abnormal_bile_duct | 1.27912914 |
49 | MP0002398_abnormal_bone_marrow | 1.27520514 |
50 | MP0005266_abnormal_metabolism | 1.27193780 |
51 | MP0003786_premature_aging | 1.24516382 |
52 | MP0005645_abnormal_hypothalamus_physiol | 1.24335633 |
53 | MP0010329_abnormal_lipoprotein_level | 1.23605229 |
54 | MP0008995_early_reproductive_senescence | 1.23100637 |
55 | MP0001666_abnormal_nutrient_absorption | 1.22006710 |
56 | MP0005464_abnormal_platelet_physiology | 1.21874241 |
57 | MP0003195_calcinosis | 1.21680366 |
58 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.18858951 |
59 | MP0000609_abnormal_liver_physiology | 1.18483679 |
60 | MP0003763_abnormal_thymus_physiology | 1.18343857 |
61 | MP0001542_abnormal_bone_strength | 1.17291557 |
62 | MP0003011_delayed_dark_adaptation | 1.15336819 |
63 | MP0001929_abnormal_gametogenesis | 1.08788736 |
64 | MP0002127_abnormal_cardiovascular_syste | 1.08599085 |
65 | MP0009643_abnormal_urine_homeostasis | 1.08348090 |
66 | MP0004215_abnormal_myocardial_fiber | 1.08160004 |
67 | MP0000598_abnormal_liver_morphology | 1.07680922 |
68 | MP0002429_abnormal_blood_cell | 1.07659175 |
69 | MP0002269_muscular_atrophy | 1.06858679 |
70 | MP0001853_heart_inflammation | 1.05431722 |
71 | MP0001529_abnormal_vocalization | 1.04112765 |
72 | MP0000358_abnormal_cell_content/ | 1.03263093 |
73 | MP0005385_cardiovascular_system_phenoty | 1.03090840 |
74 | MP0001544_abnormal_cardiovascular_syste | 1.03090840 |
75 | MP0000350_abnormal_cell_proliferation | 1.03058585 |
76 | MP0001661_extended_life_span | 1.00824274 |
77 | MP0005376_homeostasis/metabolism_phenot | 1.00199401 |
78 | MP0000703_abnormal_thymus_morphology | 0.98148626 |
79 | MP0004036_abnormal_muscle_relaxation | 0.94811355 |
80 | MP0000716_abnormal_immune_system | 0.94582335 |
81 | MP0002019_abnormal_tumor_incidence | 0.94296385 |
82 | MP0001697_abnormal_embryo_size | 0.94251711 |
83 | MP0004019_abnormal_vitamin_homeostasis | 0.94051403 |
84 | MP0005636_abnormal_mineral_homeostasis | 0.93607925 |
85 | MP0004147_increased_porphyrin_level | 0.93150231 |
86 | MP0008872_abnormal_physiological_respon | 0.93093788 |
87 | MP0004808_abnormal_hematopoietic_stem | 0.92988753 |
88 | MP0002080_prenatal_lethality | 0.92790148 |
89 | MP0009785_altered_susceptibility_to | 0.92125999 |
90 | MP0002420_abnormal_adaptive_immunity | 0.91565949 |
91 | MP0001819_abnormal_immune_cell | 0.91440520 |
92 | MP0001756_abnormal_urination | 0.90311134 |
93 | MP0009333_abnormal_splenocyte_physiolog | 0.90079855 |
94 | MP0002210_abnormal_sex_determination | 0.89921377 |
95 | MP0005408_hypopigmentation | 0.89912638 |
96 | MP0000313_abnormal_cell_death | 0.89592227 |
97 | MP0008469_abnormal_protein_level | 0.89064443 |
98 | MP0000490_abnormal_crypts_of | 0.88394256 |
99 | MP0005410_abnormal_fertilization | 0.88182816 |
100 | MP0003984_embryonic_growth_retardation | 0.87203989 |
101 | MP0001672_abnormal_embryogenesis/_devel | 0.87082580 |
102 | MP0005380_embryogenesis_phenotype | 0.87082580 |
103 | MP0003315_abnormal_perineum_morphology | 0.86355469 |
104 | MP0001881_abnormal_mammary_gland | 0.85693345 |
105 | MP0001145_abnormal_male_reproductive | 0.85692651 |
106 | MP0006072_abnormal_retinal_apoptosis | 0.85465445 |
107 | MP0002088_abnormal_embryonic_growth/wei | 0.85205848 |
108 | MP0002160_abnormal_reproductive_system | 0.84945918 |
109 | MP0001800_abnormal_humoral_immune | 0.84634263 |
110 | MP0000653_abnormal_sex_gland | 0.82296085 |
111 | MP0002452_abnormal_antigen_presenting | 0.82095390 |
112 | MP0009763_increased_sensitivity_to | 0.82048992 |
113 | MP0004145_abnormal_muscle_electrophysio | 0.81708545 |
114 | MP0005000_abnormal_immune_tolerance | 0.81444879 |
115 | MP0002132_abnormal_respiratory_system | 0.81106555 |
116 | MP0001873_stomach_inflammation | 0.79061580 |
117 | MP0001119_abnormal_female_reproductive | 0.78967201 |
118 | MP0002723_abnormal_immune_serum | 0.78635348 |
119 | MP0005389_reproductive_system_phenotype | 0.77539623 |
120 | MP0010307_abnormal_tumor_latency | 0.75526885 |
121 | MP0002095_abnormal_skin_pigmentation | 0.75365516 |
122 | MP0005397_hematopoietic_system_phenotyp | 0.75204219 |
123 | MP0001545_abnormal_hematopoietic_system | 0.75204219 |
124 | MP0001293_anophthalmia | 0.74527974 |
125 | MP0008873_increased_physiological_sensi | 0.73944098 |
126 | MP0009765_abnormal_xenobiotic_induced | 0.73308410 |
127 | MP0008789_abnormal_olfactory_epithelium | 0.72653890 |
128 | MP0005395_other_phenotype | 0.72464592 |
129 | MP0002138_abnormal_hepatobiliary_system | 0.70978765 |
130 | MP0000750_abnormal_muscle_regeneration | 0.70872376 |
131 | MP0005025_abnormal_response_to | 0.70809807 |
132 | MP0000689_abnormal_spleen_morphology | 0.70800786 |
133 | MP0004087_abnormal_muscle_fiber | 0.69742055 |
134 | MP0010352_gastrointestinal_tract_polyps | 0.69259553 |
135 | MP0002638_abnormal_pupillary_reflex | 0.68816801 |
136 | MP0003191_abnormal_cellular_cholesterol | 0.67874943 |
137 | MP0005084_abnormal_gallbladder_morpholo | 0.66557420 |
138 | MP0002006_tumorigenesis | 0.66098413 |
139 | MP0002722_abnormal_immune_system | 0.64910563 |
140 | MP0002118_abnormal_lipid_homeostasis | 0.63983001 |
141 | MP0001727_abnormal_embryo_implantation | 0.63828853 |
142 | MP0008877_abnormal_DNA_methylation | 0.63540645 |
143 | MP0000747_muscle_weakness | 0.62917982 |
144 | MP0004883_abnormal_blood_vessel | 0.62574416 |
145 | MP0008775_abnormal_heart_ventricle | 0.62502082 |
146 | MP0002086_abnormal_extraembryonic_tissu | 0.60838613 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 4.72925711 |
2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.68678646 |
3 | Hepatic necrosis (HP:0002605) | 4.55760921 |
4 | Acute encephalopathy (HP:0006846) | 4.40338276 |
5 | Hepatocellular necrosis (HP:0001404) | 4.25791795 |
6 | Mitochondrial inheritance (HP:0001427) | 4.23324749 |
7 | Increased CSF lactate (HP:0002490) | 4.13455780 |
8 | Cerebral edema (HP:0002181) | 4.10309967 |
9 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.96998900 |
10 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.96998900 |
11 | Progressive macrocephaly (HP:0004481) | 3.85910194 |
12 | Abnormality of glycolysis (HP:0004366) | 3.68032717 |
13 | Increased serum pyruvate (HP:0003542) | 3.68032717 |
14 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.58921029 |
15 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.49920766 |
16 | Increased intramyocellular lipid droplets (HP:0012240) | 3.43766973 |
17 | Increased serum lactate (HP:0002151) | 3.39810631 |
18 | Nausea (HP:0002018) | 3.39499453 |
19 | Increased muscle lipid content (HP:0009058) | 3.38770005 |
20 | Abnormal number of erythroid precursors (HP:0012131) | 3.38371910 |
21 | Lactic acidosis (HP:0003128) | 3.35627978 |
22 | Type I transferrin isoform profile (HP:0003642) | 3.33082209 |
23 | Multiple enchondromatosis (HP:0005701) | 3.29418030 |
24 | Reticulocytopenia (HP:0001896) | 3.28750974 |
25 | Lipid accumulation in hepatocytes (HP:0006561) | 3.22992680 |
26 | Oral leukoplakia (HP:0002745) | 3.18580726 |
27 | Lethargy (HP:0001254) | 3.12896566 |
28 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.09090709 |
29 | Birth length less than 3rd percentile (HP:0003561) | 3.06470421 |
30 | Reduced antithrombin III activity (HP:0001976) | 3.05644467 |
31 | Increased hepatocellular lipid droplets (HP:0006565) | 3.03832058 |
32 | Hypobetalipoproteinemia (HP:0003563) | 3.03828697 |
33 | Rhabdomyolysis (HP:0003201) | 3.01789281 |
34 | Exercise intolerance (HP:0003546) | 3.01285122 |
35 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.99529201 |
36 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.99373512 |
37 | Hyperammonemia (HP:0001987) | 2.98387092 |
38 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.95308890 |
39 | Hyperglycinemia (HP:0002154) | 2.92830120 |
40 | Dicarboxylic aciduria (HP:0003215) | 2.91936657 |
41 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.91936657 |
42 | Aplastic anemia (HP:0001915) | 2.87889799 |
43 | Respiratory failure (HP:0002878) | 2.86484018 |
44 | Hypoglycemic coma (HP:0001325) | 2.84435673 |
45 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.81134286 |
46 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.81134286 |
47 | Abnormal protein glycosylation (HP:0012346) | 2.81134286 |
48 | Abnormal glycosylation (HP:0012345) | 2.81134286 |
49 | Ragged-red muscle fibers (HP:0003200) | 2.78087168 |
50 | Redundant skin (HP:0001582) | 2.75918929 |
51 | B lymphocytopenia (HP:0010976) | 2.66298903 |
52 | Abnormality of B cell number (HP:0010975) | 2.66153603 |
53 | Hyperglycinuria (HP:0003108) | 2.64062000 |
54 | Macrocytic anemia (HP:0001972) | 2.63039164 |
55 | Generalized aminoaciduria (HP:0002909) | 2.62811257 |
56 | CNS demyelination (HP:0007305) | 2.60669246 |
57 | Abnormality of serum amino acid levels (HP:0003112) | 2.54958756 |
58 | IgM deficiency (HP:0002850) | 2.50458259 |
59 | Abnormality of glycine metabolism (HP:0010895) | 2.47212410 |
60 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.47212410 |
61 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.43946933 |
62 | Breast hypoplasia (HP:0003187) | 2.41312942 |
63 | Myoglobinuria (HP:0002913) | 2.36033909 |
64 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.32994460 |
65 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.32648619 |
66 | Abnormality of alanine metabolism (HP:0010916) | 2.32648619 |
67 | Hyperalaninemia (HP:0003348) | 2.32648619 |
68 | Proximal tubulopathy (HP:0000114) | 2.32161171 |
69 | Rough bone trabeculation (HP:0100670) | 2.31753409 |
70 | Glycosuria (HP:0003076) | 2.29141930 |
71 | Abnormality of urine glucose concentration (HP:0011016) | 2.29141930 |
72 | Methylmalonic aciduria (HP:0012120) | 2.28249696 |
73 | Intrahepatic cholestasis (HP:0001406) | 2.23341672 |
74 | Pallor (HP:0000980) | 2.23305984 |
75 | Emotional lability (HP:0000712) | 2.19705561 |
76 | Renal cortical cysts (HP:0000803) | 2.19606863 |
77 | Vomiting (HP:0002013) | 2.19581750 |
78 | 3-Methylglutaconic aciduria (HP:0003535) | 2.18280429 |
79 | Palpitations (HP:0001962) | 2.15720946 |
80 | Hypolipoproteinemia (HP:0010981) | 2.14994644 |
81 | Conjunctival hamartoma (HP:0100780) | 2.14866299 |
82 | Xanthomatosis (HP:0000991) | 2.14242338 |
83 | Leukodystrophy (HP:0002415) | 2.14111449 |
84 | Colon cancer (HP:0003003) | 2.14006348 |
85 | Panhypogammaglobulinemia (HP:0003139) | 2.12219755 |
86 | Ketosis (HP:0001946) | 2.11544200 |
87 | Degeneration of anterior horn cells (HP:0002398) | 2.10926925 |
88 | Abnormality of the anterior horn cell (HP:0006802) | 2.10926925 |
89 | Esophageal neoplasm (HP:0100751) | 2.10737463 |
90 | Neoplasm of head and neck (HP:0012288) | 2.10737463 |
91 | Secondary amenorrhea (HP:0000869) | 2.10699295 |
92 | Metabolic acidosis (HP:0001942) | 2.08407501 |
93 | Renal Fanconi syndrome (HP:0001994) | 2.07485839 |
94 | Microvesicular hepatic steatosis (HP:0001414) | 2.06429431 |
95 | Exertional dyspnea (HP:0002875) | 2.05522516 |
96 | Testicular atrophy (HP:0000029) | 2.05099359 |
97 | Agammaglobulinemia (HP:0004432) | 2.04130225 |
98 | Abnormality of the preputium (HP:0100587) | 2.03006442 |
99 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.02759480 |
100 | Type 2 muscle fiber atrophy (HP:0003554) | 2.02709607 |
101 | IgG deficiency (HP:0004315) | 2.01305818 |
102 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.01250277 |
103 | Abnormality of nucleobase metabolism (HP:0010932) | 2.00748613 |
104 | Muscle fiber atrophy (HP:0100295) | 1.98687203 |
105 | Optic disc pallor (HP:0000543) | 1.98649515 |
106 | Abnormal cartilage morphology (HP:0002763) | 1.98460442 |
107 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.95668227 |
108 | Respiratory difficulties (HP:0002880) | 1.95174265 |
109 | Premature ovarian failure (HP:0008209) | 1.94921610 |
110 | Hyperbilirubinemia (HP:0002904) | 1.94510223 |
111 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.93721846 |
112 | Gliosis (HP:0002171) | 1.92933902 |
113 | Abnormality of the prostate (HP:0008775) | 1.92579166 |
114 | Pancytopenia (HP:0001876) | 1.92271020 |
115 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.91282081 |
116 | Myelodysplasia (HP:0002863) | 1.90414820 |
117 | Abnormality of methionine metabolism (HP:0010901) | 1.90154756 |
118 | Neuroendocrine neoplasm (HP:0100634) | 1.89811841 |
119 | Meckel diverticulum (HP:0002245) | 1.89348513 |
120 | Cerebral hypomyelination (HP:0006808) | 1.88566672 |
121 | Methylmalonic acidemia (HP:0002912) | 1.87335978 |
122 | Prolonged partial thromboplastin time (HP:0003645) | 1.85065686 |
123 | Progressive muscle weakness (HP:0003323) | 1.85014280 |
124 | Microretrognathia (HP:0000308) | 1.82731352 |
125 | Cerebral palsy (HP:0100021) | 1.82492310 |
126 | Delayed CNS myelination (HP:0002188) | 1.82153368 |
127 | Progressive microcephaly (HP:0000253) | 1.81994445 |
128 | Abnormality of reticulocytes (HP:0004312) | 1.81592141 |
129 | Neoplasm of the adrenal gland (HP:0100631) | 1.81409686 |
130 | Thrombocytosis (HP:0001894) | 1.78157340 |
131 | Absent thumb (HP:0009777) | 1.78116668 |
132 | Increased IgM level (HP:0003496) | 1.77686790 |
133 | Chromsome breakage (HP:0040012) | 1.75104669 |
134 | Abnormality of the ileum (HP:0001549) | 1.73837188 |
135 | Abnormality of T cell physiology (HP:0011840) | 1.73827956 |
136 | Abnormality of renal resorption (HP:0011038) | 1.73239009 |
Rank | Gene Set | Z-score |
---|---|---|
1 | VRK2 | 5.26215159 |
2 | EIF2AK1 | 4.20114862 |
3 | NME2 | 4.18531466 |
4 | BUB1 | 3.96812291 |
5 | WEE1 | 3.81198920 |
6 | BCKDK | 3.49652496 |
7 | ACVR1B | 3.36694166 |
8 | STK16 | 2.75434809 |
9 | NEK1 | 2.62778171 |
10 | CDC7 | 2.47758122 |
11 | BRSK2 | 2.25756389 |
12 | NME1 | 2.12708446 |
13 | TSSK6 | 2.08872320 |
14 | PIM2 | 2.07017488 |
15 | NUAK1 | 2.01446944 |
16 | EIF2AK3 | 1.90601669 |
17 | VRK1 | 1.89968944 |
18 | PLK4 | 1.78578798 |
19 | PDK3 | 1.78077986 |
20 | PDK4 | 1.78077986 |
21 | MST4 | 1.68518275 |
22 | TLK1 | 1.63682694 |
23 | TESK2 | 1.57133865 |
24 | PLK1 | 1.46326720 |
25 | TAOK3 | 1.46000401 |
26 | SRPK1 | 1.45413779 |
27 | ARAF | 1.42328943 |
28 | FLT3 | 1.42204628 |
29 | KDR | 1.37863708 |
30 | MAP3K11 | 1.34592841 |
31 | NEK2 | 1.29945991 |
32 | CCNB1 | 1.28317892 |
33 | BRSK1 | 1.27467358 |
34 | MYLK | 1.25283242 |
35 | TAF1 | 1.25188583 |
36 | TTK | 1.20899630 |
37 | AURKB | 1.18566151 |
38 | CDK8 | 1.17201074 |
39 | BRAF | 1.17192482 |
40 | CDK19 | 1.15595462 |
41 | MAP4K2 | 1.15363155 |
42 | PLK3 | 1.15053653 |
43 | ZAK | 1.11291841 |
44 | DYRK3 | 1.09929386 |
45 | ABL2 | 1.06570299 |
46 | MAP2K3 | 1.04228000 |
47 | OBSCN | 1.04012272 |
48 | RPS6KB2 | 0.98776362 |
49 | TESK1 | 0.97318340 |
50 | AURKA | 0.96217672 |
51 | TGFBR1 | 0.95356933 |
52 | CDK7 | 0.93113918 |
53 | GRK7 | 0.89955020 |
54 | DAPK1 | 0.89621667 |
55 | ATR | 0.88809141 |
56 | BMPR1B | 0.87217139 |
57 | SCYL2 | 0.87209339 |
58 | PINK1 | 0.85392461 |
59 | NEK9 | 0.81530605 |
60 | LIMK1 | 0.81378969 |
61 | PIK3CG | 0.81021250 |
62 | PDK2 | 0.79853345 |
63 | TXK | 0.78694898 |
64 | RPS6KA5 | 0.76223194 |
65 | CDK4 | 0.74770557 |
66 | CSNK1G1 | 0.74663053 |
67 | MAP3K8 | 0.74157842 |
68 | PKN2 | 0.72471094 |
69 | CSNK1G3 | 0.72230977 |
70 | ILK | 0.71305121 |
71 | GRK6 | 0.69975876 |
72 | CSNK2A2 | 0.69923305 |
73 | PASK | 0.69670166 |
74 | RPS6KA4 | 0.69111245 |
75 | SMG1 | 0.68360586 |
76 | STK4 | 0.67811319 |
77 | CSNK2A1 | 0.66394407 |
78 | MAP4K1 | 0.66371024 |
79 | LRRK2 | 0.66331438 |
80 | EIF2AK2 | 0.65503294 |
81 | STK38L | 0.64641407 |
82 | MAP3K12 | 0.64265862 |
83 | TEC | 0.63648807 |
84 | MKNK1 | 0.62648250 |
85 | CLK1 | 0.61026203 |
86 | PIM1 | 0.60394675 |
87 | PBK | 0.59873033 |
88 | IRAK3 | 0.57683571 |
89 | ZAP70 | 0.54866789 |
90 | STK24 | 0.51497621 |
91 | DYRK2 | 0.49551382 |
92 | RAF1 | 0.48115856 |
93 | CHEK2 | 0.47545649 |
94 | LATS2 | 0.46332752 |
95 | MAP3K5 | 0.45879336 |
96 | IKBKB | 0.45469953 |
97 | CHEK1 | 0.45206669 |
98 | MAPKAPK3 | 0.44467761 |
99 | ALK | 0.44398453 |
100 | SYK | 0.43954802 |
101 | GRK1 | 0.43414955 |
102 | BTK | 0.43221676 |
103 | PAK1 | 0.42894963 |
104 | FES | 0.41484726 |
105 | MAP3K3 | 0.41172668 |
106 | CSNK1A1L | 0.40353688 |
107 | TTN | 0.39968234 |
108 | JAK3 | 0.39679985 |
109 | PRKCI | 0.38710863 |
110 | TIE1 | 0.38589899 |
111 | MAP2K6 | 0.38511908 |
112 | PRKCQ | 0.38401092 |
113 | CSNK1G2 | 0.36185629 |
114 | STK10 | 0.33630174 |
115 | PAK4 | 0.33575613 |
116 | ADRBK1 | 0.30253234 |
117 | MUSK | 0.29859525 |
118 | ITK | 0.29693266 |
119 | MAPKAPK5 | 0.29070622 |
120 | AKT3 | 0.28812605 |
121 | TBK1 | 0.28390794 |
122 | KIT | 0.27940896 |
123 | ATM | 0.27761994 |
124 | DAPK3 | 0.27552135 |
125 | MKNK2 | 0.27486021 |
126 | BMPR2 | 0.27329039 |
127 | CDK2 | 0.26048404 |
128 | MATK | 0.24421650 |
129 | ERBB4 | 0.23908013 |
130 | MAPK4 | 0.23149114 |
131 | EPHA2 | 0.23039867 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proteasome_Homo sapiens_hsa03050 | 3.78371331 |
2 | * Ribosome_Homo sapiens_hsa03010 | 3.58067036 |
3 | DNA replication_Homo sapiens_hsa03030 | 3.19763864 |
4 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.75804953 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 2.49587681 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 2.48128060 |
7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.44856812 |
8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.38989055 |
9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.26146567 |
10 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.25707415 |
11 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.23046294 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.10755615 |
13 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.00619105 |
14 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.93034732 |
15 | Carbon metabolism_Homo sapiens_hsa01200 | 1.85208152 |
16 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.80968029 |
17 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.79389295 |
18 | Homologous recombination_Homo sapiens_hsa03440 | 1.75118386 |
19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.72960557 |
20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.71500734 |
21 | Base excision repair_Homo sapiens_hsa03410 | 1.69943236 |
22 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.68946015 |
23 | Spliceosome_Homo sapiens_hsa03040 | 1.68789328 |
24 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.67444155 |
25 | RNA transport_Homo sapiens_hsa03013 | 1.65371258 |
26 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.64817248 |
27 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.60600446 |
28 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.59383632 |
29 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.59175948 |
30 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.55436483 |
31 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.55321971 |
32 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.54199127 |
33 | Asthma_Homo sapiens_hsa05310 | 1.50509781 |
34 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.49517072 |
35 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.44737945 |
36 | Alzheimers disease_Homo sapiens_hsa05010 | 1.44396553 |
37 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.43565395 |
38 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.29913310 |
39 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.28489731 |
40 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.26921344 |
41 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.25674070 |
42 | Sulfur relay system_Homo sapiens_hsa04122 | 1.25097729 |
43 | Allograft rejection_Homo sapiens_hsa05330 | 1.20041701 |
44 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.18836452 |
45 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.18810689 |
46 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.18622042 |
47 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.15882452 |
48 | Protein export_Homo sapiens_hsa03060 | 1.15608796 |
49 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.14422718 |
50 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.11216236 |
51 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.09926565 |
52 | Purine metabolism_Homo sapiens_hsa00230 | 1.07245440 |
53 | Peroxisome_Homo sapiens_hsa04146 | 1.06342857 |
54 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.04158243 |
55 | Cell cycle_Homo sapiens_hsa04110 | 1.04065443 |
56 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.03399461 |
57 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.02904154 |
58 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.01157297 |
59 | RNA degradation_Homo sapiens_hsa03018 | 0.98247443 |
60 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.97864713 |
61 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.97644424 |
62 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.97488799 |
63 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.96328947 |
64 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.92904011 |
65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.92259033 |
66 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.89223673 |
67 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.88624092 |
68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.86345657 |
69 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.85674929 |
70 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.84094128 |
71 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.84056295 |
72 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.83968501 |
73 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.83799174 |
74 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.82878194 |
75 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.79858276 |
76 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.79087363 |
77 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.78481003 |
78 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.77303373 |
79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.76929829 |
80 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.75179015 |
81 | Basal transcription factors_Homo sapiens_hsa03022 | 0.74106834 |
82 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.71313577 |
83 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.69534250 |
84 | Galactose metabolism_Homo sapiens_hsa00052 | 0.68020614 |
85 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.67464959 |
86 | Histidine metabolism_Homo sapiens_hsa00340 | 0.61981755 |
87 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.55993898 |
88 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.52794799 |
89 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.51559797 |
90 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.51337163 |
91 | Viral myocarditis_Homo sapiens_hsa05416 | 0.50627898 |
92 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.50482110 |
93 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.48935910 |
94 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.48476127 |
95 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.46056383 |
96 | Legionellosis_Homo sapiens_hsa05134 | 0.43235666 |
97 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.39935519 |
98 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.37113319 |
99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.37065078 |
100 | Retinol metabolism_Homo sapiens_hsa00830 | 0.34458063 |
101 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.29855789 |
102 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.29347578 |
103 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.29082833 |
104 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.27697695 |
105 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.27474589 |
106 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.27388494 |
107 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.25377092 |
108 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.22165854 |
109 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.22146774 |
110 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.19031688 |
111 | Leishmaniasis_Homo sapiens_hsa05140 | 0.18135513 |
112 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.16626240 |
113 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.15468963 |
114 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.14397629 |
115 | Thyroid cancer_Homo sapiens_hsa05216 | 0.13586464 |
116 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.09512534 |
117 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.09477956 |
118 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.08476821 |
119 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.07515236 |
120 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.06125719 |