Rank | Gene Set | Z-score |
---|---|---|
1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 8.01848022 |
2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 7.50806041 |
3 | ATP synthesis coupled proton transport (GO:0015986) | 7.50806041 |
4 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 7.05003574 |
5 | ribosomal small subunit assembly (GO:0000028) | 7.03147184 |
6 | viral transcription (GO:0019083) | 6.85904454 |
7 | translational termination (GO:0006415) | 6.65388516 |
8 | respiratory electron transport chain (GO:0022904) | 6.64183284 |
9 | electron transport chain (GO:0022900) | 6.46647435 |
10 | ribosomal small subunit biogenesis (GO:0042274) | 6.21933204 |
11 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.10267516 |
12 | cotranslational protein targeting to membrane (GO:0006613) | 6.03326272 |
13 | protein targeting to ER (GO:0045047) | 5.98669190 |
14 | translational elongation (GO:0006414) | 5.82745946 |
15 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.71735075 |
16 | protein localization to endoplasmic reticulum (GO:0070972) | 5.68961701 |
17 | ribosomal large subunit biogenesis (GO:0042273) | 5.55088619 |
18 | maturation of SSU-rRNA (GO:0030490) | 5.51008786 |
19 | cellular protein complex disassembly (GO:0043624) | 5.22477060 |
20 | viral life cycle (GO:0019058) | 5.16801596 |
21 | translational initiation (GO:0006413) | 5.09013025 |
22 | protein complex biogenesis (GO:0070271) | 5.05598921 |
23 | oxidative phosphorylation (GO:0006119) | 5.01816234 |
24 | regulation of mitochondrial translation (GO:0070129) | 4.97887450 |
25 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.96021201 |
26 | NADH dehydrogenase complex assembly (GO:0010257) | 4.96021201 |
27 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.96021201 |
28 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.89958313 |
29 | translation (GO:0006412) | 4.89761466 |
30 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.72708896 |
31 | proteasome assembly (GO:0043248) | 4.53436644 |
32 | DNA deamination (GO:0045006) | 4.45786090 |
33 | protein complex disassembly (GO:0043241) | 4.37103953 |
34 | maturation of 5.8S rRNA (GO:0000460) | 4.28246117 |
35 | macromolecular complex disassembly (GO:0032984) | 4.23759284 |
36 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.22009845 |
37 | termination of RNA polymerase III transcription (GO:0006386) | 4.22009845 |
38 | CENP-A containing nucleosome assembly (GO:0034080) | 4.09127686 |
39 | chromatin remodeling at centromere (GO:0031055) | 4.08992884 |
40 | cellular component biogenesis (GO:0044085) | 3.98404020 |
41 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.96936097 |
42 | chaperone-mediated protein transport (GO:0072321) | 3.95752534 |
43 | cullin deneddylation (GO:0010388) | 3.95160765 |
44 | protein targeting to membrane (GO:0006612) | 3.94103146 |
45 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.93645083 |
46 | respiratory chain complex IV assembly (GO:0008535) | 3.93550697 |
47 | ATP biosynthetic process (GO:0006754) | 3.92720206 |
48 | aerobic respiration (GO:0009060) | 3.90437572 |
49 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.88772508 |
50 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.85270665 |
51 | establishment of integrated proviral latency (GO:0075713) | 3.84817878 |
52 | quinone biosynthetic process (GO:1901663) | 3.83737228 |
53 | ubiquinone biosynthetic process (GO:0006744) | 3.83737228 |
54 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.83613936 |
55 | DNA replication checkpoint (GO:0000076) | 3.83382236 |
56 | cytochrome complex assembly (GO:0017004) | 3.79771109 |
57 | protein targeting to mitochondrion (GO:0006626) | 3.79567756 |
58 | protein neddylation (GO:0045116) | 3.76570995 |
59 | GTP biosynthetic process (GO:0006183) | 3.74955565 |
60 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.68862712 |
61 | IMP biosynthetic process (GO:0006188) | 3.66437531 |
62 | protein deneddylation (GO:0000338) | 3.66077173 |
63 | formation of translation preinitiation complex (GO:0001731) | 3.64631216 |
64 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.64617371 |
65 | establishment of protein localization to mitochondrion (GO:0072655) | 3.63784709 |
66 | nuclear pore complex assembly (GO:0051292) | 3.62485107 |
67 | protein localization to kinetochore (GO:0034501) | 3.58024384 |
68 | inner mitochondrial membrane organization (GO:0007007) | 3.56601742 |
69 | mitotic metaphase plate congression (GO:0007080) | 3.55100275 |
70 | nuclear pore organization (GO:0006999) | 3.53829381 |
71 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.52513149 |
72 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.52427890 |
73 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.50637009 |
74 | protein localization to mitochondrion (GO:0070585) | 3.48818715 |
75 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.48396972 |
76 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.48177840 |
77 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.47992852 |
78 | negative regulation of ligase activity (GO:0051352) | 3.47992852 |
79 | histone exchange (GO:0043486) | 3.46871831 |
80 | purine nucleobase biosynthetic process (GO:0009113) | 3.44776288 |
81 | hydrogen ion transmembrane transport (GO:1902600) | 3.43279141 |
82 | IMP metabolic process (GO:0046040) | 3.41555966 |
83 | ubiquinone metabolic process (GO:0006743) | 3.41504119 |
84 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.41347452 |
85 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.36736376 |
86 | DNA strand elongation (GO:0022616) | 3.36014676 |
87 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.33277794 |
88 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.33277794 |
89 | nucleobase biosynthetic process (GO:0046112) | 3.32868021 |
90 | mRNA catabolic process (GO:0006402) | 3.32136505 |
91 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.31235014 |
92 | regulation of centriole replication (GO:0046599) | 3.30328287 |
93 | rRNA processing (GO:0006364) | 3.29712470 |
94 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.29421647 |
95 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.29421647 |
96 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.29421647 |
97 | pseudouridine synthesis (GO:0001522) | 3.29228558 |
98 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.28729915 |
99 | UTP biosynthetic process (GO:0006228) | 3.27365731 |
100 | mitochondrial transport (GO:0006839) | 3.26442019 |
101 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.25901775 |
102 | DNA replication-independent nucleosome organization (GO:0034724) | 3.25901775 |
103 | ribosome assembly (GO:0042255) | 3.25377038 |
104 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.22911287 |
105 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.22911287 |
106 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.20864771 |
107 | spliceosomal snRNP assembly (GO:0000387) | 3.20492715 |
108 | protein localization to chromosome, centromeric region (GO:0071459) | 3.19859933 |
109 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.19355161 |
110 | tricarboxylic acid cycle (GO:0006099) | 3.17755388 |
111 | 7-methylguanosine mRNA capping (GO:0006370) | 3.15702533 |
112 | rRNA metabolic process (GO:0016072) | 3.14564762 |
113 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.13233778 |
114 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.12889582 |
115 | 7-methylguanosine RNA capping (GO:0009452) | 3.11685275 |
116 | RNA capping (GO:0036260) | 3.11685275 |
117 | cellular respiration (GO:0045333) | 3.11515208 |
118 | iron-sulfur cluster assembly (GO:0016226) | 3.10745282 |
119 | metallo-sulfur cluster assembly (GO:0031163) | 3.10745282 |
120 | ribosome biogenesis (GO:0042254) | 3.09416504 |
121 | regulation of translational fidelity (GO:0006450) | 3.08435055 |
122 | amino acid activation (GO:0043038) | 3.05704415 |
123 | tRNA aminoacylation (GO:0043039) | 3.05704415 |
124 | RNA catabolic process (GO:0006401) | 3.05343441 |
125 | UTP metabolic process (GO:0046051) | 3.03741606 |
126 | spliceosomal complex assembly (GO:0000245) | 3.02930166 |
127 | rRNA modification (GO:0000154) | 3.01477421 |
128 | tRNA aminoacylation for protein translation (GO:0006418) | 3.01044911 |
129 | metaphase plate congression (GO:0051310) | 3.00833975 |
130 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.00104234 |
131 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.94983196 |
132 | non-recombinational repair (GO:0000726) | 2.94340014 |
133 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.94340014 |
134 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.89877477 |
135 | termination of RNA polymerase I transcription (GO:0006363) | 2.88435908 |
136 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.87988511 |
137 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.87988511 |
138 | DNA damage response, detection of DNA damage (GO:0042769) | 2.84997292 |
139 | mitotic sister chromatid segregation (GO:0000070) | 2.83845836 |
140 | establishment of viral latency (GO:0019043) | 2.82736608 |
141 | replication fork processing (GO:0031297) | 2.80721588 |
142 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.79791277 |
143 | DNA unwinding involved in DNA replication (GO:0006268) | 2.79490999 |
144 | protein K6-linked ubiquitination (GO:0085020) | 2.77092660 |
145 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.76999343 |
146 | mitochondrial RNA metabolic process (GO:0000959) | 2.76370807 |
147 | telomere maintenance via recombination (GO:0000722) | 2.75951144 |
Rank | Gene Set | Z-score |
---|---|---|
1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.16611366 |
2 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.61015135 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.53158342 |
4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.27815812 |
5 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.20031701 |
6 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.18187191 |
7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.86916282 |
8 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.84765463 |
9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.75553025 |
10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.38617366 |
11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.36640033 |
12 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.19499924 |
13 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.09751622 |
14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.99838901 |
15 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.89308535 |
16 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.76253520 |
17 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.75495923 |
18 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.72875528 |
19 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.72875373 |
20 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.72536978 |
21 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.63343444 |
22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.61522274 |
23 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.53089540 |
24 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.50434192 |
25 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.45819146 |
26 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.44729317 |
27 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.34296120 |
28 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.31879493 |
29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.30740679 |
30 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.22778828 |
31 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.21538541 |
32 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.19998085 |
33 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.18392783 |
34 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.06096116 |
35 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.02664863 |
36 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.01645853 |
37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.00646993 |
38 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.92488738 |
39 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.91241781 |
40 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.89775349 |
41 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.88424305 |
42 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.84129498 |
43 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.83728886 |
44 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.81810743 |
45 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.80373979 |
46 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.78933758 |
47 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.76751415 |
48 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69158074 |
49 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.68243091 |
50 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.67599317 |
51 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.57940681 |
52 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.53487647 |
53 | EWS_26573619_Chip-Seq_HEK293_Human | 1.53061971 |
54 | FUS_26573619_Chip-Seq_HEK293_Human | 1.47696904 |
55 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.46940174 |
56 | * BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.44340614 |
57 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.42745956 |
58 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.41973331 |
59 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.41472616 |
60 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.35556243 |
61 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.34932408 |
62 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.32280238 |
63 | * CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.30090083 |
64 | VDR_22108803_ChIP-Seq_LS180_Human | 1.28009436 |
65 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.21869389 |
66 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.21579733 |
67 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.20491154 |
68 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.19417035 |
69 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.15214471 |
70 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12940636 |
71 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.12051366 |
72 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.12030734 |
73 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.11809797 |
74 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.09577733 |
75 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.08392190 |
76 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.08371419 |
77 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.08151439 |
78 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.07039993 |
79 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.02609669 |
80 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.02001083 |
81 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.00272706 |
82 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.00084358 |
83 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.99015591 |
84 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.98595045 |
85 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.98235267 |
86 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.97854100 |
87 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.96078183 |
88 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.95602616 |
89 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.93738658 |
90 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.93082680 |
91 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.89670033 |
92 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.89604543 |
93 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.89288836 |
94 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.89258766 |
95 | * FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.88922051 |
96 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.88055472 |
97 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.87922902 |
98 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.83943251 |
99 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.83724856 |
100 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.82086076 |
101 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.81028542 |
102 | * STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.80636868 |
103 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.79956245 |
104 | * IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.79129838 |
105 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.78323030 |
106 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.76938952 |
107 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.76493176 |
108 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.76206069 |
109 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.75772793 |
110 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.74590082 |
111 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73605916 |
112 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.73499251 |
113 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 0.72438646 |
114 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.71719237 |
115 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.71304199 |
116 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.69404655 |
117 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.68547476 |
118 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.68382366 |
119 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.68151358 |
120 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.67629272 |
121 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.66359479 |
122 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.65919632 |
123 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.65890099 |
124 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.65527740 |
125 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.64485157 |
126 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.64183561 |
127 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.63654601 |
128 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.63397999 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0009379_abnormal_foot_pigmentation | 6.01350290 |
2 | MP0003646_muscle_fatigue | 4.25468575 |
3 | MP0006036_abnormal_mitochondrial_physio | 3.88045137 |
4 | MP0002837_dystrophic_cardiac_calcinosis | 3.74441212 |
5 | MP0003693_abnormal_embryo_hatching | 3.14771247 |
6 | MP0003186_abnormal_redox_activity | 2.94412117 |
7 | MP0000749_muscle_degeneration | 2.66214011 |
8 | MP0003806_abnormal_nucleotide_metabolis | 2.62959007 |
9 | MP0004957_abnormal_blastocyst_morpholog | 2.57617735 |
10 | MP0004215_abnormal_myocardial_fiber | 2.57187002 |
11 | MP0004084_abnormal_cardiac_muscle | 2.56987622 |
12 | MP0006035_abnormal_mitochondrial_morpho | 2.47086437 |
13 | MP0003890_abnormal_embryonic-extraembry | 2.34966058 |
14 | MP0003941_abnormal_skin_development | 2.27391072 |
15 | MP0005330_cardiomyopathy | 2.15281123 |
16 | MP0001529_abnormal_vocalization | 2.11626486 |
17 | MP0000751_myopathy | 1.99175117 |
18 | MP0001293_anophthalmia | 1.94856471 |
19 | MP0006292_abnormal_olfactory_placode | 1.92482186 |
20 | MP0001764_abnormal_homeostasis | 1.91252232 |
21 | MP0004036_abnormal_muscle_relaxation | 1.90869678 |
22 | MP0009697_abnormal_copulation | 1.89357777 |
23 | MP0004147_increased_porphyrin_level | 1.87594805 |
24 | MP0002163_abnormal_gland_morphology | 1.84128578 |
25 | MP0002132_abnormal_respiratory_system | 1.83801489 |
26 | MP0008932_abnormal_embryonic_tissue | 1.79850488 |
27 | MP0000372_irregular_coat_pigmentation | 1.75427242 |
28 | MP0010030_abnormal_orbit_morphology | 1.73526651 |
29 | MP0000750_abnormal_muscle_regeneration | 1.72033100 |
30 | MP0002102_abnormal_ear_morphology | 1.67430269 |
31 | MP0008877_abnormal_DNA_methylation | 1.66843774 |
32 | MP0008058_abnormal_DNA_repair | 1.59660927 |
33 | MP0003937_abnormal_limbs/digits/tail_de | 1.59407632 |
34 | MP0003077_abnormal_cell_cycle | 1.59386142 |
35 | MP0002638_abnormal_pupillary_reflex | 1.58910685 |
36 | MP0010094_abnormal_chromosome_stability | 1.58520337 |
37 | MP0003221_abnormal_cardiomyocyte_apopto | 1.57692611 |
38 | MP0003136_yellow_coat_color | 1.52256392 |
39 | MP0003656_abnormal_erythrocyte_physiolo | 1.51657635 |
40 | MP0003137_abnormal_impulse_conducting | 1.47997758 |
41 | MP0001697_abnormal_embryo_size | 1.46452766 |
42 | MP0006072_abnormal_retinal_apoptosis | 1.45880791 |
43 | MP0002234_abnormal_pharynx_morphology | 1.45249979 |
44 | MP0002972_abnormal_cardiac_muscle | 1.43702965 |
45 | MP0008775_abnormal_heart_ventricle | 1.39963013 |
46 | MP0001730_embryonic_growth_arrest | 1.38130367 |
47 | MP0003718_maternal_effect | 1.35646935 |
48 | MP0002084_abnormal_developmental_patter | 1.34949123 |
49 | MP0001672_abnormal_embryogenesis/_devel | 1.30669963 |
50 | MP0005380_embryogenesis_phenotype | 1.30669963 |
51 | MP0009333_abnormal_splenocyte_physiolog | 1.28383018 |
52 | MP0001853_heart_inflammation | 1.26798687 |
53 | MP0002085_abnormal_embryonic_tissue | 1.26026850 |
54 | MP0001544_abnormal_cardiovascular_syste | 1.26008932 |
55 | MP0005385_cardiovascular_system_phenoty | 1.26008932 |
56 | MP0003567_abnormal_fetal_cardiomyocyte | 1.24966818 |
57 | MP0003011_delayed_dark_adaptation | 1.24207052 |
58 | MP0000350_abnormal_cell_proliferation | 1.23572162 |
59 | MP0005187_abnormal_penis_morphology | 1.22636108 |
60 | MP0001286_abnormal_eye_development | 1.22143174 |
61 | MP0004145_abnormal_muscle_electrophysio | 1.20931009 |
62 | MP0003786_premature_aging | 1.20732089 |
63 | MP0002106_abnormal_muscle_physiology | 1.20709190 |
64 | MP0005084_abnormal_gallbladder_morpholo | 1.18694703 |
65 | MP0004484_altered_response_of | 1.17355622 |
66 | MP0008789_abnormal_olfactory_epithelium | 1.17176652 |
67 | MP0005620_abnormal_muscle_contractility | 1.16979344 |
68 | MP0009785_altered_susceptibility_to | 1.15502104 |
69 | MP0003984_embryonic_growth_retardation | 1.13701381 |
70 | MP0005266_abnormal_metabolism | 1.13299494 |
71 | MP0002210_abnormal_sex_determination | 1.12255182 |
72 | MP0002736_abnormal_nociception_after | 1.12078023 |
73 | MP0002088_abnormal_embryonic_growth/wei | 1.11341738 |
74 | MP0002148_abnormal_hypersensitivity_rea | 1.10394096 |
75 | MP0002697_abnormal_eye_size | 1.10294401 |
76 | MP0003195_calcinosis | 1.10253888 |
77 | MP0004087_abnormal_muscle_fiber | 1.09458533 |
78 | MP0005636_abnormal_mineral_homeostasis | 1.08082541 |
79 | MP0000358_abnormal_cell_content/ | 1.07219517 |
80 | MP0000343_altered_response_to | 1.06919336 |
81 | MP0000647_abnormal_sebaceous_gland | 1.06592405 |
82 | MP0002080_prenatal_lethality | 1.06445818 |
83 | MP0003123_paternal_imprinting | 1.05425338 |
84 | MP0001929_abnormal_gametogenesis | 1.04216096 |
85 | MP0002233_abnormal_nose_morphology | 1.03511322 |
86 | MP0003119_abnormal_digestive_system | 1.03297155 |
87 | MP0005083_abnormal_biliary_tract | 1.03041576 |
88 | MP0002332_abnormal_exercise_endurance | 1.02431682 |
89 | MP0008004_abnormal_stomach_pH | 1.01156545 |
90 | MP0003111_abnormal_nucleus_morphology | 1.00414901 |
91 | MP0005332_abnormal_amino_acid | 0.99827198 |
92 | MP0003950_abnormal_plasma_membrane | 0.98341446 |
93 | MP0005369_muscle_phenotype | 0.98102342 |
94 | MP0010307_abnormal_tumor_latency | 0.97551474 |
95 | MP0004233_abnormal_muscle_weight | 0.97447921 |
96 | MP0000631_abnormal_neuroendocrine_gland | 0.96400081 |
97 | MP0004197_abnormal_fetal_growth/weight/ | 0.96309060 |
98 | MP0003121_genomic_imprinting | 0.96078321 |
99 | MP0000490_abnormal_crypts_of | 0.94582270 |
100 | MP0002160_abnormal_reproductive_system | 0.94322307 |
101 | MP0002111_abnormal_tail_morphology | 0.94208705 |
102 | MP0002876_abnormal_thyroid_physiology | 0.93889268 |
103 | MP0005253_abnormal_eye_physiology | 0.93512599 |
104 | MP0001986_abnormal_taste_sensitivity | 0.93345729 |
105 | MP0008007_abnormal_cellular_replicative | 0.92950175 |
106 | MP0005376_homeostasis/metabolism_phenot | 0.92236456 |
107 | MP0004142_abnormal_muscle_tone | 0.91593475 |
108 | MP0000759_abnormal_skeletal_muscle | 0.90563057 |
109 | MP0002127_abnormal_cardiovascular_syste | 0.89870931 |
110 | MP0009672_abnormal_birth_weight | 0.89069801 |
111 | MP0001984_abnormal_olfaction | 0.89050347 |
112 | MP0001188_hyperpigmentation | 0.87295784 |
113 | MP0005391_vision/eye_phenotype | 0.87292520 |
114 | MP0001145_abnormal_male_reproductive | 0.86417485 |
115 | MP0001346_abnormal_lacrimal_gland | 0.86340784 |
116 | MP0004133_heterotaxia | 0.86281032 |
117 | MP0006276_abnormal_autonomic_nervous | 0.85937841 |
118 | MP0008995_early_reproductive_senescence | 0.85678509 |
119 | MP0001661_extended_life_span | 0.85330038 |
120 | MP0000653_abnormal_sex_gland | 0.85114475 |
121 | MP0001905_abnormal_dopamine_level | 0.84206329 |
122 | MP0003315_abnormal_perineum_morphology | 0.84021355 |
123 | MP0005165_increased_susceptibility_to | 0.83737422 |
124 | MP0002751_abnormal_autonomic_nervous | 0.80843896 |
125 | MP0001299_abnormal_eye_distance/ | 0.80805522 |
126 | MP0005551_abnormal_eye_electrophysiolog | 0.80745464 |
127 | MP0005379_endocrine/exocrine_gland_phen | 0.79826788 |
128 | MP0003861_abnormal_nervous_system | 0.79819038 |
129 | MP0002269_muscular_atrophy | 0.78643485 |
130 | MP0006138_congestive_heart_failure | 0.78578623 |
131 | MP0002938_white_spotting | 0.78142386 |
132 | MP0003724_increased_susceptibility_to | 0.77915726 |
133 | MP0003698_abnormal_male_reproductive | 0.77469214 |
134 | MP0008057_abnormal_DNA_replication | 0.76604288 |
135 | MP0003755_abnormal_palate_morphology | 0.76201699 |
136 | MP0000049_abnormal_middle_ear | 0.74840062 |
137 | MP0004043_abnormal_pH_regulation | 0.74602139 |
138 | MP0005319_abnormal_enzyme/_coenzyme | 0.74329701 |
139 | MP0002092_abnormal_eye_morphology | 0.73470167 |
140 | MP0005408_hypopigmentation | 0.73412097 |
141 | MP0001835_abnormal_antigen_presentation | 0.71996336 |
142 | MP0001881_abnormal_mammary_gland | 0.71028647 |
143 | MP0002086_abnormal_extraembryonic_tissu | 0.67729581 |
144 | MP0003763_abnormal_thymus_physiology | 0.67264685 |
145 | MP0008469_abnormal_protein_level | 0.67098552 |
146 | MP0002095_abnormal_skin_pigmentation | 0.67042165 |
147 | MP0010630_abnormal_cardiac_muscle | 0.66777019 |
148 | MP0004381_abnormal_hair_follicle | 0.66199030 |
149 | MP0005394_taste/olfaction_phenotype | 0.66180214 |
150 | MP0005499_abnormal_olfactory_system | 0.66180214 |
151 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.65621631 |
152 | MP0002277_abnormal_respiratory_mucosa | 0.65120277 |
153 | MP0001727_abnormal_embryo_implantation | 0.65025357 |
154 | MP0003385_abnormal_body_wall | 0.64715333 |
155 | MP0000313_abnormal_cell_death | 0.64412574 |
156 | MP0001542_abnormal_bone_strength | 0.64011348 |
157 | MP0005195_abnormal_posterior_eye | 0.62435362 |
158 | MP0000230_abnormal_systemic_arterial | 0.61552116 |
159 | MP0001663_abnormal_digestive_system | 0.61182019 |
160 | MP0002396_abnormal_hematopoietic_system | 0.60259888 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 6.83441923 |
2 | Mitochondrial inheritance (HP:0001427) | 6.43403959 |
3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 6.39766009 |
4 | Hepatocellular necrosis (HP:0001404) | 6.21339240 |
5 | Hepatic necrosis (HP:0002605) | 5.96962229 |
6 | Acute encephalopathy (HP:0006846) | 5.79530943 |
7 | Increased CSF lactate (HP:0002490) | 5.77651696 |
8 | Progressive macrocephaly (HP:0004481) | 5.62266654 |
9 | Increased hepatocellular lipid droplets (HP:0006565) | 5.12270630 |
10 | Lipid accumulation in hepatocytes (HP:0006561) | 4.89644457 |
11 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.82450770 |
12 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.60298382 |
13 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.60298382 |
14 | Abnormal number of erythroid precursors (HP:0012131) | 4.47821781 |
15 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 4.44223573 |
16 | Cerebral edema (HP:0002181) | 4.37774852 |
17 | Increased intramyocellular lipid droplets (HP:0012240) | 4.35060005 |
18 | Increased serum lactate (HP:0002151) | 4.29772846 |
19 | Lactic acidosis (HP:0003128) | 4.18805579 |
20 | Respiratory failure (HP:0002878) | 4.11839771 |
21 | Reticulocytopenia (HP:0001896) | 4.11078615 |
22 | Increased muscle lipid content (HP:0009058) | 4.09884648 |
23 | Increased serum pyruvate (HP:0003542) | 4.06571065 |
24 | Abnormality of glycolysis (HP:0004366) | 4.06571065 |
25 | Exercise intolerance (HP:0003546) | 4.05906815 |
26 | Renal Fanconi syndrome (HP:0001994) | 4.01235335 |
27 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.74195620 |
28 | 3-Methylglutaconic aciduria (HP:0003535) | 3.74111805 |
29 | Macrocytic anemia (HP:0001972) | 3.59989985 |
30 | Exertional dyspnea (HP:0002875) | 3.50906748 |
31 | Chromsome breakage (HP:0040012) | 3.42237624 |
32 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.38046769 |
33 | Respiratory difficulties (HP:0002880) | 3.29709758 |
34 | Optic disc pallor (HP:0000543) | 3.22088173 |
35 | Leukodystrophy (HP:0002415) | 3.12070263 |
36 | Pallor (HP:0000980) | 3.08536043 |
37 | Abnormality of alanine metabolism (HP:0010916) | 3.08390037 |
38 | Hyperalaninemia (HP:0003348) | 3.08390037 |
39 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.08390037 |
40 | Colon cancer (HP:0003003) | 3.07512026 |
41 | CNS demyelination (HP:0007305) | 2.99851532 |
42 | Birth length less than 3rd percentile (HP:0003561) | 2.97079306 |
43 | Lethargy (HP:0001254) | 2.79092551 |
44 | Microvesicular hepatic steatosis (HP:0001414) | 2.75878582 |
45 | Glycosuria (HP:0003076) | 2.65656909 |
46 | Abnormality of urine glucose concentration (HP:0011016) | 2.65656909 |
47 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.63007476 |
48 | Meckel diverticulum (HP:0002245) | 2.62016100 |
49 | Dicarboxylic aciduria (HP:0003215) | 2.60821384 |
50 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.60821384 |
51 | Abnormality of the labia minora (HP:0012880) | 2.60099350 |
52 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.56888631 |
53 | Abnormality of methionine metabolism (HP:0010901) | 2.54622937 |
54 | Abnormal hemoglobin (HP:0011902) | 2.53006816 |
55 | Abnormality of renal resorption (HP:0011038) | 2.51729155 |
56 | Emotional lability (HP:0000712) | 2.51673762 |
57 | Abnormality of the ileum (HP:0001549) | 2.51295445 |
58 | Abnormality of chromosome stability (HP:0003220) | 2.46557115 |
59 | Generalized aminoaciduria (HP:0002909) | 2.42794699 |
60 | Ragged-red muscle fibers (HP:0003200) | 2.42023175 |
61 | Rhabdomyolysis (HP:0003201) | 2.38836051 |
62 | Multiple enchondromatosis (HP:0005701) | 2.38372062 |
63 | Abnormality of the preputium (HP:0100587) | 2.34382966 |
64 | Hyperphosphaturia (HP:0003109) | 2.29060640 |
65 | Palpitations (HP:0001962) | 2.28630582 |
66 | Oral leukoplakia (HP:0002745) | 2.23059684 |
67 | Nausea (HP:0002018) | 2.21937788 |
68 | Gliosis (HP:0002171) | 2.19374482 |
69 | Methylmalonic aciduria (HP:0012120) | 2.19267795 |
70 | Hypoplasia of the pons (HP:0012110) | 2.16512608 |
71 | Sudden death (HP:0001699) | 2.15517656 |
72 | Myoglobinuria (HP:0002913) | 2.11240691 |
73 | Cerebral hypomyelination (HP:0006808) | 2.07399922 |
74 | Muscle hypertrophy of the lower extremities (HP:0008968) | 2.05104757 |
75 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.04800826 |
76 | Abnormality of the pons (HP:0007361) | 2.04063150 |
77 | Abnormal lung lobation (HP:0002101) | 2.02188726 |
78 | Ventricular tachycardia (HP:0004756) | 2.00573437 |
79 | Calf muscle hypertrophy (HP:0008981) | 1.99984829 |
80 | Bilateral microphthalmos (HP:0007633) | 1.98898672 |
81 | Type I transferrin isoform profile (HP:0003642) | 1.98392015 |
82 | Conjunctival hamartoma (HP:0100780) | 1.97026661 |
83 | Vomiting (HP:0002013) | 1.95457464 |
84 | Triphalangeal thumb (HP:0001199) | 1.94828656 |
85 | X-linked dominant inheritance (HP:0001423) | 1.93077023 |
86 | Small intestinal stenosis (HP:0012848) | 1.92910676 |
87 | Duodenal stenosis (HP:0100867) | 1.92910676 |
88 | Aplastic anemia (HP:0001915) | 1.91923784 |
89 | Lipoatrophy (HP:0100578) | 1.90459056 |
90 | Hyperglycinuria (HP:0003108) | 1.89722840 |
91 | Absent thumb (HP:0009777) | 1.88787945 |
92 | Pancreatic cysts (HP:0001737) | 1.88559245 |
93 | Neuroendocrine neoplasm (HP:0100634) | 1.88400630 |
94 | Methylmalonic acidemia (HP:0002912) | 1.87543364 |
95 | Abnormality of the carotid arteries (HP:0005344) | 1.87418807 |
96 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.84866059 |
97 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.84761487 |
98 | Congenital, generalized hypertrichosis (HP:0004540) | 1.84326631 |
99 | Abnormality of homocysteine metabolism (HP:0010919) | 1.82974243 |
100 | Homocystinuria (HP:0002156) | 1.82974243 |
101 | Progressive muscle weakness (HP:0003323) | 1.82343847 |
102 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.82090611 |
103 | Pancytopenia (HP:0001876) | 1.81639011 |
104 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.81119034 |
105 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.81079401 |
106 | Abnormality of DNA repair (HP:0003254) | 1.80234303 |
107 | Abnormality of serum amino acid levels (HP:0003112) | 1.79626527 |
108 | Amniotic constriction ring (HP:0009775) | 1.78166515 |
109 | Abnormality of placental membranes (HP:0011409) | 1.78166515 |
110 | Reduced antithrombin III activity (HP:0001976) | 1.77539350 |
111 | Abnormality of the duodenum (HP:0002246) | 1.77501637 |
112 | Abnormal urine phosphate concentration (HP:0012599) | 1.75329441 |
113 | Sloping forehead (HP:0000340) | 1.74075978 |
114 | Pancreatic fibrosis (HP:0100732) | 1.74067851 |
115 | Abnormality of glycine metabolism (HP:0010895) | 1.73387458 |
116 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.73387458 |
117 | Esophageal neoplasm (HP:0100751) | 1.72693494 |
118 | Neoplasm of head and neck (HP:0012288) | 1.72693494 |
119 | Progressive external ophthalmoplegia (HP:0000590) | 1.71910964 |
120 | Hyperglycinemia (HP:0002154) | 1.71642338 |
121 | Blindness (HP:0000618) | 1.71106194 |
122 | Horseshoe kidney (HP:0000085) | 1.71032507 |
123 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.71031156 |
124 | Embryonal renal neoplasm (HP:0011794) | 1.70441924 |
125 | Hypoglycemic coma (HP:0001325) | 1.69689232 |
126 | Stenosis of the external auditory canal (HP:0000402) | 1.68593676 |
127 | Megaloblastic anemia (HP:0001889) | 1.66986289 |
128 | Oligodactyly (hands) (HP:0001180) | 1.66982179 |
129 | Testicular atrophy (HP:0000029) | 1.66321103 |
130 | Exercise-induced muscle cramps (HP:0003710) | 1.66195437 |
131 | Trismus (HP:0000211) | 1.65599756 |
132 | Abnormal protein glycosylation (HP:0012346) | 1.65489161 |
133 | Abnormal glycosylation (HP:0012345) | 1.65489161 |
134 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.65489161 |
135 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.65489161 |
136 | Metabolic acidosis (HP:0001942) | 1.64408212 |
137 | Rough bone trabeculation (HP:0100670) | 1.64189980 |
138 | Hyperammonemia (HP:0001987) | 1.63438646 |
139 | Absent radius (HP:0003974) | 1.62147176 |
140 | Sclerocornea (HP:0000647) | 1.61690095 |
141 | Proximal tubulopathy (HP:0000114) | 1.60656373 |
142 | Dilated cardiomyopathy (HP:0001644) | 1.59509111 |
143 | Bifid tongue (HP:0010297) | 1.59099810 |
144 | Partial agenesis of the corpus callosum (HP:0001338) | 1.58807421 |
145 | Renal tubular dysfunction (HP:0000124) | 1.58466280 |
146 | Volvulus (HP:0002580) | 1.58408848 |
147 | Myelodysplasia (HP:0002863) | 1.58193790 |
148 | Facial cleft (HP:0002006) | 1.58057422 |
149 | Pheochromocytoma (HP:0002666) | 1.57682606 |
150 | Abnormality of reticulocytes (HP:0004312) | 1.57587991 |
151 | Renal cortical cysts (HP:0000803) | 1.57262919 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NME2 | 4.68906014 |
2 | TLK1 | 4.13983720 |
3 | BUB1 | 3.75681346 |
4 | EIF2AK1 | 3.74336065 |
5 | NME1 | 3.64305481 |
6 | STK16 | 3.34464819 |
7 | VRK2 | 3.04342444 |
8 | BCKDK | 2.86656905 |
9 | MYLK | 2.38825606 |
10 | VRK1 | 2.29877553 |
11 | EIF2AK3 | 2.06822550 |
12 | TAF1 | 2.06380599 |
13 | MST4 | 2.04118425 |
14 | SRPK1 | 2.02875263 |
15 | OBSCN | 1.93297576 |
16 | LMTK2 | 1.88642398 |
17 | MAP3K12 | 1.88267039 |
18 | WEE1 | 1.88184180 |
19 | PBK | 1.88076992 |
20 | PIM2 | 1.81881539 |
21 | CHEK2 | 1.61045672 |
22 | NUAK1 | 1.51686271 |
23 | PLK4 | 1.45577240 |
24 | ILK | 1.41780619 |
25 | IRAK3 | 1.40881296 |
26 | PDK3 | 1.38454952 |
27 | PDK4 | 1.38454952 |
28 | PNCK | 1.30907805 |
29 | ZAK | 1.28193833 |
30 | BRSK2 | 1.27392754 |
31 | WNK3 | 1.26536704 |
32 | CDK19 | 1.23842902 |
33 | PDK2 | 1.22545701 |
34 | LIMK1 | 1.22003049 |
35 | MAP3K11 | 1.20651407 |
36 | ATR | 1.09967570 |
37 | BRAF | 1.08701201 |
38 | GRK7 | 1.07844630 |
39 | TESK2 | 1.01895866 |
40 | STK24 | 1.01728817 |
41 | NEK9 | 1.00816231 |
42 | ARAF | 1.00740211 |
43 | MAPKAPK5 | 0.94434580 |
44 | KDR | 0.94305670 |
45 | TRIM28 | 0.93233373 |
46 | NEK1 | 0.92910796 |
47 | MAP4K2 | 0.92785364 |
48 | TESK1 | 0.92130628 |
49 | ABL2 | 0.91466608 |
50 | DAPK3 | 0.91198964 |
51 | IRAK4 | 0.90777082 |
52 | AURKB | 0.90117279 |
53 | CASK | 0.90097116 |
54 | AURKA | 0.88353629 |
55 | NEK2 | 0.86686102 |
56 | STK38L | 0.85479459 |
57 | PIK3CA | 0.84355048 |
58 | ERBB4 | 0.83826297 |
59 | CDK7 | 0.83587840 |
60 | ATM | 0.82978728 |
61 | TGFBR1 | 0.81513591 |
62 | CSNK1G1 | 0.80944947 |
63 | TNIK | 0.79996327 |
64 | ACVR1B | 0.79421016 |
65 | TEC | 0.78872969 |
66 | MUSK | 0.78096529 |
67 | PLK1 | 0.76965954 |
68 | STK3 | 0.76962517 |
69 | EIF2AK2 | 0.76283698 |
70 | STK39 | 0.76263956 |
71 | CSNK1G3 | 0.76090173 |
72 | CDC7 | 0.75424498 |
73 | CHEK1 | 0.75407587 |
74 | CDK8 | 0.75138394 |
75 | MKNK1 | 0.74777865 |
76 | ALK | 0.74138383 |
77 | CSNK2A1 | 0.71901949 |
78 | TSSK6 | 0.71667155 |
79 | PIK3CG | 0.71597840 |
80 | ERBB3 | 0.70638239 |
81 | LATS1 | 0.67408036 |
82 | SCYL2 | 0.66999232 |
83 | BLK | 0.65703009 |
84 | PLK2 | 0.64923611 |
85 | RPS6KA4 | 0.64633072 |
86 | CSNK2A2 | 0.64540736 |
87 | CSNK1A1L | 0.63502631 |
88 | PASK | 0.63450845 |
89 | TXK | 0.63243958 |
90 | CSNK1E | 0.62889119 |
91 | WNK4 | 0.62493136 |
92 | CCNB1 | 0.62210140 |
93 | PHKG1 | 0.61330391 |
94 | PHKG2 | 0.61330391 |
95 | MAP3K4 | 0.61144250 |
96 | RPS6KA5 | 0.60387058 |
97 | MKNK2 | 0.60244312 |
98 | INSRR | 0.58393576 |
99 | EEF2K | 0.57767019 |
100 | BRSK1 | 0.56263311 |
101 | BMPR1B | 0.55789832 |
102 | ADRBK2 | 0.54893435 |
103 | CDK1 | 0.54300987 |
104 | RPS6KB2 | 0.52194884 |
105 | CSNK1G2 | 0.51951892 |
106 | FRK | 0.51865061 |
107 | PLK3 | 0.50835923 |
108 | TTN | 0.50679154 |
109 | DYRK3 | 0.50530612 |
110 | FLT3 | 0.50150696 |
111 | TIE1 | 0.49669856 |
112 | GRK1 | 0.49242361 |
113 | MAP2K6 | 0.46793687 |
114 | CDK2 | 0.46708479 |
115 | MAP2K7 | 0.45064747 |
116 | BCR | 0.44555482 |
117 | CDK3 | 0.43981654 |
118 | BMPR2 | 0.43426614 |
119 | STK4 | 0.41828028 |
120 | PINK1 | 0.41577417 |
121 | FGFR1 | 0.40993741 |
122 | LATS2 | 0.40558141 |
123 | CAMK2G | 0.40161738 |
124 | MAPKAPK3 | 0.39920001 |
125 | PAK1 | 0.39796569 |
126 | DYRK2 | 0.39278101 |
127 | PRKDC | 0.39109221 |
128 | OXSR1 | 0.38542615 |
129 | CAMK2D | 0.38443690 |
130 | PRKG2 | 0.37874225 |
131 | MAP3K3 | 0.35232475 |
132 | CLK1 | 0.35007363 |
133 | ZAP70 | 0.33983212 |
134 | AKT2 | 0.32921612 |
135 | IRAK2 | 0.31948079 |
136 | IRAK1 | 0.30155324 |
137 | TYK2 | 0.30105971 |
138 | MAP2K3 | 0.30012682 |
139 | LRRK2 | 0.29261863 |
140 | TTK | 0.29108092 |
141 | MET | 0.28475883 |
142 | MST1R | 0.28046245 |
143 | MAP4K1 | 0.26253843 |
144 | PRKCD | 0.25022065 |
145 | IKBKB | 0.24762837 |
146 | PRKACA | 0.24359879 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Ribosome_Homo sapiens_hsa03010 | 5.42785215 |
2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 5.07332211 |
3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.57733069 |
4 | Proteasome_Homo sapiens_hsa03050 | 3.98223069 |
5 | Huntingtons disease_Homo sapiens_hsa05016 | 3.30756473 |
6 | Alzheimers disease_Homo sapiens_hsa05010 | 3.21300787 |
7 | RNA polymerase_Homo sapiens_hsa03020 | 3.16840032 |
8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.98666111 |
9 | Protein export_Homo sapiens_hsa03060 | 2.82373027 |
10 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.50717027 |
11 | DNA replication_Homo sapiens_hsa03030 | 2.32279221 |
12 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.26444704 |
13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.07849740 |
14 | Mismatch repair_Homo sapiens_hsa03430 | 2.03037630 |
15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.02456522 |
16 | Homologous recombination_Homo sapiens_hsa03440 | 1.86595051 |
17 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.76816816 |
18 | Spliceosome_Homo sapiens_hsa03040 | 1.70748215 |
19 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.52362407 |
20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.44794975 |
21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.40378652 |
22 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.36471170 |
23 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.33104711 |
24 | Base excision repair_Homo sapiens_hsa03410 | 1.31027064 |
25 | Carbon metabolism_Homo sapiens_hsa01200 | 1.30879809 |
26 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.29403028 |
27 | RNA transport_Homo sapiens_hsa03013 | 1.23864454 |
28 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.23671387 |
29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.19595648 |
30 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.17301317 |
31 | Sulfur relay system_Homo sapiens_hsa04122 | 1.15847436 |
32 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.15284691 |
33 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.13571690 |
34 | Purine metabolism_Homo sapiens_hsa00230 | 1.13551497 |
35 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.12330142 |
36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.03695060 |
37 | Basal transcription factors_Homo sapiens_hsa03022 | 0.99990300 |
38 | RNA degradation_Homo sapiens_hsa03018 | 0.95461001 |
39 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.89404398 |
40 | Metabolic pathways_Homo sapiens_hsa01100 | 0.87096785 |
41 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.84722342 |
42 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.84155712 |
43 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.83022404 |
44 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.81642473 |
45 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.78062350 |
46 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.76994521 |
47 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.76293764 |
48 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.73523723 |
49 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.72008488 |
50 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.67188598 |
51 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.67142856 |
52 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.65492575 |
53 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.62535579 |
54 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.62186157 |
55 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.61775744 |
56 | Peroxisome_Homo sapiens_hsa04146 | 0.59367765 |
57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.59112515 |
58 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.57635264 |
59 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.53546155 |
60 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.52012980 |
61 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.51493248 |
62 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.50486284 |
63 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.49155375 |
64 | Cell cycle_Homo sapiens_hsa04110 | 0.47592415 |
65 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.47328311 |
66 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.46991534 |
67 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.46971778 |
68 | Phototransduction_Homo sapiens_hsa04744 | 0.45788499 |
69 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.45497965 |
70 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.44022353 |
71 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.43647311 |
72 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.43554360 |
73 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.43476874 |
74 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.42216405 |
75 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.42075958 |
76 | Galactose metabolism_Homo sapiens_hsa00052 | 0.40217706 |
77 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.40163347 |
78 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.39639715 |
79 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.39413742 |
80 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.38783210 |
81 | Lysine degradation_Homo sapiens_hsa00310 | 0.38434271 |
82 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.36271301 |
83 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.35682702 |
84 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.34782440 |
85 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.33417587 |
86 | Legionellosis_Homo sapiens_hsa05134 | 0.32590495 |
87 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.32466100 |
88 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.31043666 |
89 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.29818703 |
90 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.29348834 |
91 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.28683729 |
92 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.28355692 |
93 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.27944787 |
94 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.26995326 |
95 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.26052192 |
96 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.25979608 |
97 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.25667093 |
98 | Allograft rejection_Homo sapiens_hsa05330 | 0.24859188 |
99 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.24501503 |
100 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.23703835 |
101 | Alcoholism_Homo sapiens_hsa05034 | 0.23497771 |
102 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.23459187 |
103 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.22316447 |
104 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.22081170 |
105 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.19558098 |
106 | Asthma_Homo sapiens_hsa05310 | 0.18110712 |
107 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.17399654 |
108 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.17292347 |
109 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.16560916 |
110 | Nicotine addiction_Homo sapiens_hsa05033 | 0.16311706 |
111 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.16100086 |
112 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.15474887 |
113 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.14688532 |
114 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.12471838 |
115 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.11828170 |
116 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.11453403 |
117 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.11243606 |
118 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.11075312 |
119 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.10894436 |
120 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.09449184 |
121 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.09030606 |
122 | Other glycan degradation_Homo sapiens_hsa00511 | 0.08933259 |
123 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.08745570 |
124 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.08574052 |
125 | Retinol metabolism_Homo sapiens_hsa00830 | 0.08282081 |