

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 6.04213927 |
| 2 | cullin deneddylation (GO:0010388) | 5.68208086 |
| 3 | protein deneddylation (GO:0000338) | 5.38920011 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.14833374 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.77694996 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 4.77694996 |
| 7 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.51482420 |
| 8 | ribosome assembly (GO:0042255) | 4.51257540 |
| 9 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.36147164 |
| 10 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.27571914 |
| 11 | NADH dehydrogenase complex assembly (GO:0010257) | 4.27571914 |
| 12 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.27571914 |
| 13 | maturation of 5.8S rRNA (GO:0000460) | 4.22980309 |
| 14 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.17287375 |
| 15 | rRNA modification (GO:0000154) | 4.16796371 |
| 16 | chaperone-mediated protein transport (GO:0072321) | 4.12702386 |
| 17 | protein complex biogenesis (GO:0070271) | 4.10222294 |
| 18 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.07736298 |
| 19 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.05180322 |
| 20 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.03907215 |
| 21 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.03907215 |
| 22 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.92523783 |
| 23 | respiratory electron transport chain (GO:0022904) | 3.91049632 |
| 24 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.89558690 |
| 25 | electron transport chain (GO:0022900) | 3.86827753 |
| 26 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.84695700 |
| 27 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.78926213 |
| 28 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.78926213 |
| 29 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.78926213 |
| 30 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.75293211 |
| 31 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.74959142 |
| 32 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.74959142 |
| 33 | DNA deamination (GO:0045006) | 3.74926302 |
| 34 | negative regulation of ligase activity (GO:0051352) | 3.67539232 |
| 35 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.67539232 |
| 36 | metallo-sulfur cluster assembly (GO:0031163) | 3.64293612 |
| 37 | iron-sulfur cluster assembly (GO:0016226) | 3.64293612 |
| 38 | mannosylation (GO:0097502) | 3.61780834 |
| 39 | DNA damage response, detection of DNA damage (GO:0042769) | 3.60306466 |
| 40 | respiratory chain complex IV assembly (GO:0008535) | 3.60185476 |
| 41 | ribosomal large subunit biogenesis (GO:0042273) | 3.59688979 |
| 42 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.59253775 |
| 43 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.59253775 |
| 44 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.55536880 |
| 45 | rRNA methylation (GO:0031167) | 3.55297597 |
| 46 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.48393027 |
| 47 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.46271879 |
| 48 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.46271879 |
| 49 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.44444375 |
| 50 | GTP biosynthetic process (GO:0006183) | 3.39696151 |
| 51 | amino acid activation (GO:0043038) | 3.38082703 |
| 52 | tRNA aminoacylation (GO:0043039) | 3.38082703 |
| 53 | tRNA aminoacylation for protein translation (GO:0006418) | 3.36036280 |
| 54 | protein targeting to mitochondrion (GO:0006626) | 3.33979837 |
| 55 | protein neddylation (GO:0045116) | 3.30003856 |
| 56 | peptidyl-histidine modification (GO:0018202) | 3.28547078 |
| 57 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.22053451 |
| 58 | termination of RNA polymerase III transcription (GO:0006386) | 3.22053451 |
| 59 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.20552401 |
| 60 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.20443103 |
| 61 | protein localization to mitochondrion (GO:0070585) | 3.20134097 |
| 62 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.19726445 |
| 63 | mitochondrial RNA metabolic process (GO:0000959) | 3.19564409 |
| 64 | aldehyde catabolic process (GO:0046185) | 3.19337238 |
| 65 | ribosome biogenesis (GO:0042254) | 3.19108966 |
| 66 | tRNA processing (GO:0008033) | 3.17624687 |
| 67 | tRNA metabolic process (GO:0006399) | 3.17192123 |
| 68 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.17148402 |
| 69 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.16959584 |
| 70 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.16880797 |
| 71 | protein-cofactor linkage (GO:0018065) | 3.14087147 |
| 72 | establishment of protein localization to mitochondrion (GO:0072655) | 3.12838979 |
| 73 | spliceosomal snRNP assembly (GO:0000387) | 3.10153550 |
| 74 | transcription from mitochondrial promoter (GO:0006390) | 3.10047658 |
| 75 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.03684858 |
| 76 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.02830605 |
| 77 | positive regulation of ligase activity (GO:0051351) | 3.01748354 |
| 78 | DNA double-strand break processing (GO:0000729) | 3.01077936 |
| 79 | intracellular protein transmembrane import (GO:0044743) | 3.00622779 |
| 80 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.99869099 |
| 81 | regulation of helicase activity (GO:0051095) | 2.99470930 |
| 82 | amino acid salvage (GO:0043102) | 2.99313606 |
| 83 | L-methionine salvage (GO:0071267) | 2.99313606 |
| 84 | L-methionine biosynthetic process (GO:0071265) | 2.99313606 |
| 85 | positive regulation of mitochondrial fission (GO:0090141) | 2.99306261 |
| 86 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.97956263 |
| 87 | ribonucleoprotein complex disassembly (GO:0032988) | 2.97840212 |
| 88 | hydrogen ion transmembrane transport (GO:1902600) | 2.97655068 |
| 89 | oxidative phosphorylation (GO:0006119) | 2.96342209 |
| 90 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.95714227 |
| 91 | cellular component biogenesis (GO:0044085) | 2.95118099 |
| 92 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.93550665 |
| 93 | organelle disassembly (GO:1903008) | 2.93331584 |
| 94 | cytochrome complex assembly (GO:0017004) | 2.93036575 |
| 95 | UTP metabolic process (GO:0046051) | 2.92170964 |
| 96 | purine nucleotide salvage (GO:0032261) | 2.91216135 |
| 97 | IMP biosynthetic process (GO:0006188) | 2.89509912 |
| 98 | UTP biosynthetic process (GO:0006228) | 2.86660480 |
| 99 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.85955114 |
| 100 | ATP biosynthetic process (GO:0006754) | 2.84775245 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.54268882 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.88404032 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.45469918 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.80176647 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.54330560 |
| 6 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.38730768 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.36245240 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.07558622 |
| 9 | VDR_23849224_ChIP-Seq_CD4+_Human | 3.04102603 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.81256000 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.71596321 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.61418462 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.53806581 |
| 14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.51999472 |
| 15 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.41377671 |
| 16 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.39988280 |
| 17 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.31739461 |
| 18 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.27461434 |
| 19 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.23459132 |
| 20 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.19962775 |
| 21 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.12080899 |
| 22 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.08939650 |
| 23 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.05411137 |
| 24 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.02791515 |
| 25 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.01052844 |
| 26 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.99498849 |
| 27 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.97949509 |
| 28 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.95604122 |
| 29 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.87336615 |
| 30 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.86966238 |
| 31 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.86951777 |
| 32 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.83624275 |
| 33 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.76950576 |
| 34 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.75464247 |
| 35 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.74372216 |
| 36 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.66530912 |
| 37 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.65698655 |
| 38 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.65402520 |
| 39 | VDR_22108803_ChIP-Seq_LS180_Human | 1.64793420 |
| 40 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.64622695 |
| 41 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.62704557 |
| 42 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.56994687 |
| 43 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.55316612 |
| 44 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.52493326 |
| 45 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.52200795 |
| 46 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.48344231 |
| 47 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.47639646 |
| 48 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.45976454 |
| 49 | EWS_26573619_Chip-Seq_HEK293_Human | 1.45666854 |
| 50 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.45484348 |
| 51 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.41896360 |
| 52 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.36378810 |
| 53 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.35492115 |
| 54 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.30553762 |
| 55 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.29886724 |
| 56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.29736995 |
| 57 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.25659828 |
| 58 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17742532 |
| 59 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.15634293 |
| 60 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.14919704 |
| 61 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.11664950 |
| 62 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.11085171 |
| 63 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.08427712 |
| 64 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.08175673 |
| 65 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.07848372 |
| 66 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.07470483 |
| 67 | P300_19829295_ChIP-Seq_ESCs_Human | 1.05936741 |
| 68 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.04982923 |
| 69 | AR_20517297_ChIP-Seq_VCAP_Human | 1.03672187 |
| 70 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.02810095 |
| 71 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.02810095 |
| 72 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.02783952 |
| 73 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.02739226 |
| 74 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.01099769 |
| 75 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.98446310 |
| 76 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.97096473 |
| 77 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.96508095 |
| 78 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.96123895 |
| 79 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.95406266 |
| 80 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.93585680 |
| 81 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.93447076 |
| 82 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.92647622 |
| 83 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.92599665 |
| 84 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.91441357 |
| 85 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.91188292 |
| 86 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.87061465 |
| 87 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.85331268 |
| 88 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.85331268 |
| 89 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.84601394 |
| 90 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.84477527 |
| 91 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84135394 |
| 92 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.83730162 |
| 93 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.81907227 |
| 94 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.80575923 |
| 95 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.80558532 |
| 96 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.80136385 |
| 97 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.78120604 |
| 98 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.77979336 |
| 99 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.77979336 |
| 100 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.76236989 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 3.69411809 |
| 2 | MP0002102_abnormal_ear_morphology | 3.08480696 |
| 3 | MP0008058_abnormal_DNA_repair | 2.96835127 |
| 4 | MP0006036_abnormal_mitochondrial_physio | 2.83208104 |
| 5 | MP0001984_abnormal_olfaction | 2.80774627 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.76763473 |
| 7 | MP0001529_abnormal_vocalization | 2.54256786 |
| 8 | MP0003880_abnormal_central_pattern | 2.43631939 |
| 9 | MP0002837_dystrophic_cardiac_calcinosis | 2.28136415 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.24146627 |
| 11 | MP0001764_abnormal_homeostasis | 2.19663777 |
| 12 | MP0006035_abnormal_mitochondrial_morpho | 2.17787547 |
| 13 | MP0004957_abnormal_blastocyst_morpholog | 2.14452604 |
| 14 | MP0003786_premature_aging | 2.05017517 |
| 15 | MP0004147_increased_porphyrin_level | 2.01696690 |
| 16 | MP0005075_abnormal_melanosome_morpholog | 2.01349182 |
| 17 | MP0010094_abnormal_chromosome_stability | 1.94763472 |
| 18 | MP0003693_abnormal_embryo_hatching | 1.93932898 |
| 19 | MP0003195_calcinosis | 1.92250856 |
| 20 | MP0008995_early_reproductive_senescence | 1.88527915 |
| 21 | MP0008872_abnormal_physiological_respon | 1.86756588 |
| 22 | MP0003186_abnormal_redox_activity | 1.84779435 |
| 23 | MP0005253_abnormal_eye_physiology | 1.83478533 |
| 24 | MP0009697_abnormal_copulation | 1.73114980 |
| 25 | MP0003718_maternal_effect | 1.72546286 |
| 26 | MP0005551_abnormal_eye_electrophysiolog | 1.70854021 |
| 27 | MP0006276_abnormal_autonomic_nervous | 1.69563224 |
| 28 | MP0008789_abnormal_olfactory_epithelium | 1.69414104 |
| 29 | MP0005084_abnormal_gallbladder_morpholo | 1.68564081 |
| 30 | MP0003011_delayed_dark_adaptation | 1.68238992 |
| 31 | MP0008057_abnormal_DNA_replication | 1.65823737 |
| 32 | MP0002638_abnormal_pupillary_reflex | 1.64894852 |
| 33 | MP0005646_abnormal_pituitary_gland | 1.57908313 |
| 34 | MP0005167_abnormal_blood-brain_barrier | 1.54076294 |
| 35 | MP0002163_abnormal_gland_morphology | 1.50939688 |
| 36 | MP0000372_irregular_coat_pigmentation | 1.48085636 |
| 37 | MP0009046_muscle_twitch | 1.47838252 |
| 38 | MP0002736_abnormal_nociception_after | 1.45761529 |
| 39 | MP0005379_endocrine/exocrine_gland_phen | 1.42618117 |
| 40 | MP0003111_abnormal_nucleus_morphology | 1.37877022 |
| 41 | MP0008932_abnormal_embryonic_tissue | 1.35698308 |
| 42 | MP0004133_heterotaxia | 1.33462147 |
| 43 | MP0005499_abnormal_olfactory_system | 1.33216462 |
| 44 | MP0005394_taste/olfaction_phenotype | 1.33216462 |
| 45 | MP0010386_abnormal_urinary_bladder | 1.32376280 |
| 46 | MP0003077_abnormal_cell_cycle | 1.26501082 |
| 47 | MP0005645_abnormal_hypothalamus_physiol | 1.23529335 |
| 48 | MP0002751_abnormal_autonomic_nervous | 1.23321579 |
| 49 | MP0001986_abnormal_taste_sensitivity | 1.16943786 |
| 50 | MP0002090_abnormal_vision | 1.15402174 |
| 51 | MP0000358_abnormal_cell_content/ | 1.14670576 |
| 52 | MP0001968_abnormal_touch/_nociception | 1.11819232 |
| 53 | MP0002938_white_spotting | 1.11067483 |
| 54 | MP0008875_abnormal_xenobiotic_pharmacok | 1.10053950 |
| 55 | MP0004142_abnormal_muscle_tone | 1.07085836 |
| 56 | MP0005266_abnormal_metabolism | 1.05108252 |
| 57 | MP0005332_abnormal_amino_acid | 1.04119114 |
| 58 | MP0002234_abnormal_pharynx_morphology | 1.03155808 |
| 59 | MP0001293_anophthalmia | 1.02776118 |
| 60 | MP0003646_muscle_fatigue | 1.01917239 |
| 61 | MP0000749_muscle_degeneration | 1.01370120 |
| 62 | MP0003787_abnormal_imprinting | 1.01117582 |
| 63 | MP0002272_abnormal_nervous_system | 1.00626787 |
| 64 | MP0000631_abnormal_neuroendocrine_gland | 0.96555498 |
| 65 | MP0001501_abnormal_sleep_pattern | 0.96371341 |
| 66 | MP0005671_abnormal_response_to | 0.94242920 |
| 67 | MP0006292_abnormal_olfactory_placode | 0.92791516 |
| 68 | MP0001905_abnormal_dopamine_level | 0.92485418 |
| 69 | MP0004215_abnormal_myocardial_fiber | 0.90741296 |
| 70 | MP0004782_abnormal_surfactant_physiolog | 0.85614900 |
| 71 | MP0009745_abnormal_behavioral_response | 0.85413122 |
| 72 | MP0008007_abnormal_cellular_replicative | 0.83222435 |
| 73 | MP0001929_abnormal_gametogenesis | 0.81078202 |
| 74 | MP0001485_abnormal_pinna_reflex | 0.80359137 |
| 75 | MP0005408_hypopigmentation | 0.78822686 |
| 76 | MP0008873_increased_physiological_sensi | 0.78538197 |
| 77 | MP0010368_abnormal_lymphatic_system | 0.75858149 |
| 78 | MP0005636_abnormal_mineral_homeostasis | 0.74933747 |
| 79 | MP0005389_reproductive_system_phenotype | 0.74773152 |
| 80 | MP0002332_abnormal_exercise_endurance | 0.74588927 |
| 81 | MP0002735_abnormal_chemical_nociception | 0.73755871 |
| 82 | MP0002572_abnormal_emotion/affect_behav | 0.73673910 |
| 83 | MP0005647_abnormal_sex_gland | 0.73422917 |
| 84 | MP0001486_abnormal_startle_reflex | 0.72512837 |
| 85 | MP0002909_abnormal_adrenal_gland | 0.71942996 |
| 86 | MP0005376_homeostasis/metabolism_phenot | 0.70652483 |
| 87 | MP0004885_abnormal_endolymph | 0.70487029 |
| 88 | MP0005330_cardiomyopathy | 0.70395477 |
| 89 | MP0002210_abnormal_sex_determination | 0.69852498 |
| 90 | MP0005391_vision/eye_phenotype | 0.69779995 |
| 91 | MP0009764_decreased_sensitivity_to | 0.69470064 |
| 92 | MP0005410_abnormal_fertilization | 0.68377095 |
| 93 | MP0004145_abnormal_muscle_electrophysio | 0.66935766 |
| 94 | MP0003866_abnormal_defecation | 0.66516733 |
| 95 | MP0002069_abnormal_eating/drinking_beha | 0.65137823 |
| 96 | MP0002132_abnormal_respiratory_system | 0.64909234 |
| 97 | MP0002229_neurodegeneration | 0.62864991 |
| 98 | MP0005195_abnormal_posterior_eye | 0.62266711 |
| 99 | MP0003567_abnormal_fetal_cardiomyocyte | 0.62185224 |
| 100 | MP0002752_abnormal_somatic_nervous | 0.61388209 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.74756216 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.45902142 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.34337862 |
| 4 | Acute encephalopathy (HP:0006846) | 4.33945312 |
| 5 | Hepatocellular necrosis (HP:0001404) | 4.23670982 |
| 6 | Increased CSF lactate (HP:0002490) | 4.19974436 |
| 7 | Progressive macrocephaly (HP:0004481) | 4.12369595 |
| 8 | Hepatic necrosis (HP:0002605) | 3.98877214 |
| 9 | Abnormality of the labia minora (HP:0012880) | 3.71124696 |
| 10 | Type I transferrin isoform profile (HP:0003642) | 3.48499331 |
| 11 | Cerebral edema (HP:0002181) | 3.42617373 |
| 12 | Increased serum lactate (HP:0002151) | 3.38981262 |
| 13 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.32992131 |
| 14 | Abnormality of alanine metabolism (HP:0010916) | 3.32992131 |
| 15 | Hyperalaninemia (HP:0003348) | 3.32992131 |
| 16 | Lipid accumulation in hepatocytes (HP:0006561) | 3.32701985 |
| 17 | Increased hepatocellular lipid droplets (HP:0006565) | 3.30709128 |
| 18 | 3-Methylglutaconic aciduria (HP:0003535) | 3.30222676 |
| 19 | Methylmalonic acidemia (HP:0002912) | 3.27668294 |
| 20 | Abnormality of methionine metabolism (HP:0010901) | 3.21160648 |
| 21 | Increased serum pyruvate (HP:0003542) | 3.17200546 |
| 22 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.11101567 |
| 23 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.11101567 |
| 24 | Pancreatic cysts (HP:0001737) | 3.09560295 |
| 25 | Lactic acidosis (HP:0003128) | 3.03292065 |
| 26 | Increased intramyocellular lipid droplets (HP:0012240) | 3.01885650 |
| 27 | Abnormality of glycolysis (HP:0004366) | 2.98720561 |
| 28 | Medial flaring of the eyebrow (HP:0010747) | 2.87215388 |
| 29 | Aplastic anemia (HP:0001915) | 2.85616883 |
| 30 | Renal Fanconi syndrome (HP:0001994) | 2.81582479 |
| 31 | Abnormality of midbrain morphology (HP:0002418) | 2.80974913 |
| 32 | Molar tooth sign on MRI (HP:0002419) | 2.80974913 |
| 33 | Abnormal protein glycosylation (HP:0012346) | 2.79360120 |
| 34 | Abnormal glycosylation (HP:0012345) | 2.79360120 |
| 35 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.79360120 |
| 36 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.79360120 |
| 37 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.77033613 |
| 38 | Neonatal respiratory distress (HP:0002643) | 2.75896371 |
| 39 | Respiratory failure (HP:0002878) | 2.72941614 |
| 40 | True hermaphroditism (HP:0010459) | 2.72930330 |
| 41 | Methylmalonic aciduria (HP:0012120) | 2.70481481 |
| 42 | Abnormality of serum amino acid levels (HP:0003112) | 2.63018239 |
| 43 | Increased muscle lipid content (HP:0009058) | 2.60926845 |
| 44 | Abnormality of the anterior horn cell (HP:0006802) | 2.59832621 |
| 45 | Degeneration of anterior horn cells (HP:0002398) | 2.59832621 |
| 46 | Exercise intolerance (HP:0003546) | 2.54643421 |
| 47 | Pancreatic fibrosis (HP:0100732) | 2.54018672 |
| 48 | Congenital primary aphakia (HP:0007707) | 2.44016118 |
| 49 | Nephrogenic diabetes insipidus (HP:0009806) | 2.41517173 |
| 50 | Lethargy (HP:0001254) | 2.39299273 |
| 51 | CNS demyelination (HP:0007305) | 2.38025799 |
| 52 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.35326262 |
| 53 | Optic disc pallor (HP:0000543) | 2.34708555 |
| 54 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.31835098 |
| 55 | Gait imbalance (HP:0002141) | 2.31048318 |
| 56 | Hyperglycinemia (HP:0002154) | 2.28120064 |
| 57 | Posterior subcapsular cataract (HP:0007787) | 2.25071256 |
| 58 | Microvesicular hepatic steatosis (HP:0001414) | 2.23196582 |
| 59 | Bile duct proliferation (HP:0001408) | 2.17976218 |
| 60 | Abnormal biliary tract physiology (HP:0012439) | 2.17976218 |
| 61 | Hyperglycinuria (HP:0003108) | 2.13363551 |
| 62 | Abolished electroretinogram (ERG) (HP:0000550) | 2.13171597 |
| 63 | Exertional dyspnea (HP:0002875) | 2.11786454 |
| 64 | Leukodystrophy (HP:0002415) | 2.10062489 |
| 65 | Emotional lability (HP:0000712) | 2.06184488 |
| 66 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.05122679 |
| 67 | Abnormality of glycine metabolism (HP:0010895) | 2.05122679 |
| 68 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.03832278 |
| 69 | Generalized aminoaciduria (HP:0002909) | 2.03565641 |
| 70 | Congenital, generalized hypertrichosis (HP:0004540) | 2.01784316 |
| 71 | Ketoacidosis (HP:0001993) | 2.00793109 |
| 72 | Neoplasm of the adrenal gland (HP:0100631) | 1.98100981 |
| 73 | Retinal dysplasia (HP:0007973) | 1.95610666 |
| 74 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.95132839 |
| 75 | Oral leukoplakia (HP:0002745) | 1.91101511 |
| 76 | Palpitations (HP:0001962) | 1.88363977 |
| 77 | Gonadotropin excess (HP:0000837) | 1.87623012 |
| 78 | Pancytopenia (HP:0001876) | 1.87589277 |
| 79 | Abnormality of urine glucose concentration (HP:0011016) | 1.87415998 |
| 80 | Glycosuria (HP:0003076) | 1.87415998 |
| 81 | Abnormality of vitamin B metabolism (HP:0004340) | 1.86907442 |
| 82 | Cerebral hypomyelination (HP:0006808) | 1.85372678 |
| 83 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.83680606 |
| 84 | Type II lissencephaly (HP:0007260) | 1.79562256 |
| 85 | IgM deficiency (HP:0002850) | 1.79049476 |
| 86 | Dicarboxylic aciduria (HP:0003215) | 1.78233698 |
| 87 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.78233698 |
| 88 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.77953851 |
| 89 | Genital tract atresia (HP:0001827) | 1.77838489 |
| 90 | Hypomagnesemia (HP:0002917) | 1.77448053 |
| 91 | Vaginal atresia (HP:0000148) | 1.73010769 |
| 92 | Cystic liver disease (HP:0006706) | 1.71835489 |
| 93 | Brushfield spots (HP:0001088) | 1.69956890 |
| 94 | Nephronophthisis (HP:0000090) | 1.69454184 |
| 95 | Ketosis (HP:0001946) | 1.67390659 |
| 96 | Abnormality of renal resorption (HP:0011038) | 1.66740139 |
| 97 | Chronic hepatic failure (HP:0100626) | 1.65940314 |
| 98 | Hypothermia (HP:0002045) | 1.65797224 |
| 99 | CNS hypomyelination (HP:0003429) | 1.65442693 |
| 100 | Sensorimotor neuropathy (HP:0007141) | 1.64948011 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 4.37290170 |
| 2 | TIE1 | 3.91527629 |
| 3 | STK16 | 3.25325366 |
| 4 | VRK2 | 3.16324077 |
| 5 | SRPK1 | 3.15051035 |
| 6 | TRIM28 | 3.00077789 |
| 7 | EIF2AK3 | 2.89921890 |
| 8 | EIF2AK1 | 2.66613715 |
| 9 | PBK | 2.51366399 |
| 10 | MST4 | 2.31589867 |
| 11 | MAP4K2 | 2.29814133 |
| 12 | ZAK | 2.05057643 |
| 13 | PDK2 | 2.00205245 |
| 14 | PLK3 | 1.99688133 |
| 15 | BCKDK | 1.81478784 |
| 16 | GRK1 | 1.73752402 |
| 17 | MAP3K12 | 1.71054297 |
| 18 | BMPR1B | 1.70655398 |
| 19 | FRK | 1.65684368 |
| 20 | VRK1 | 1.60622525 |
| 21 | NEK1 | 1.59440121 |
| 22 | BUB1 | 1.48636820 |
| 23 | CDC7 | 1.39607117 |
| 24 | TEC | 1.34507614 |
| 25 | NME1 | 1.33955910 |
| 26 | WNK3 | 1.32388094 |
| 27 | CDK19 | 1.31061362 |
| 28 | NUAK1 | 1.30398098 |
| 29 | CSNK1G3 | 1.28554279 |
| 30 | DAPK1 | 1.28346968 |
| 31 | MKNK1 | 1.11579897 |
| 32 | MAPKAPK5 | 1.08512397 |
| 33 | CSNK1A1L | 1.07964791 |
| 34 | ADRBK2 | 1.06939531 |
| 35 | CSNK1G1 | 1.03680036 |
| 36 | BMPR2 | 1.00252181 |
| 37 | ERBB3 | 0.98694962 |
| 38 | MAP2K7 | 0.95438616 |
| 39 | TNIK | 0.95238057 |
| 40 | LIMK1 | 0.94540051 |
| 41 | PASK | 0.94207800 |
| 42 | MKNK2 | 0.92124276 |
| 43 | CSNK1G2 | 0.91166379 |
| 44 | MAP3K4 | 0.90788022 |
| 45 | OXSR1 | 0.90315767 |
| 46 | SCYL2 | 0.89638309 |
| 47 | KDR | 0.88604159 |
| 48 | BCR | 0.87615980 |
| 49 | CDK8 | 0.86750481 |
| 50 | CASK | 0.84109153 |
| 51 | TESK1 | 0.82767954 |
| 52 | ALK | 0.82712463 |
| 53 | ATR | 0.82136044 |
| 54 | PLK1 | 0.81722573 |
| 55 | DYRK2 | 0.81678054 |
| 56 | NME2 | 0.77094721 |
| 57 | TLK1 | 0.76892842 |
| 58 | TAOK3 | 0.75297101 |
| 59 | EPHA4 | 0.75290310 |
| 60 | PHKG2 | 0.73254213 |
| 61 | PHKG1 | 0.73254213 |
| 62 | PLK2 | 0.70854039 |
| 63 | TTK | 0.63906889 |
| 64 | AURKB | 0.61573641 |
| 65 | INSRR | 0.60363115 |
| 66 | PLK4 | 0.60006889 |
| 67 | SIK3 | 0.59606354 |
| 68 | TESK2 | 0.59597128 |
| 69 | TGFBR1 | 0.56995803 |
| 70 | ACVR1B | 0.50400573 |
| 71 | WNK4 | 0.50005867 |
| 72 | ERBB4 | 0.49585877 |
| 73 | FGFR2 | 0.48102001 |
| 74 | MAPKAPK3 | 0.46796022 |
| 75 | CSNK2A1 | 0.45824549 |
| 76 | PIM2 | 0.45660769 |
| 77 | CSNK2A2 | 0.45366505 |
| 78 | CCNB1 | 0.44543997 |
| 79 | ATM | 0.44107015 |
| 80 | MYLK | 0.44027453 |
| 81 | FER | 0.40272773 |
| 82 | PINK1 | 0.39974861 |
| 83 | RPS6KA5 | 0.37387383 |
| 84 | MAPK13 | 0.36064058 |
| 85 | CAMK2A | 0.34600858 |
| 86 | ITK | 0.34353147 |
| 87 | EIF2AK2 | 0.33654415 |
| 88 | ARAF | 0.33058395 |
| 89 | RPS6KA4 | 0.31848878 |
| 90 | TAF1 | 0.31307725 |
| 91 | DAPK3 | 0.30495307 |
| 92 | AURKA | 0.30491874 |
| 93 | CDK9 | 0.29785679 |
| 94 | MAP3K5 | 0.29330724 |
| 95 | PAK4 | 0.28519981 |
| 96 | PAK3 | 0.27719763 |
| 97 | DYRK3 | 0.27633748 |
| 98 | STK38L | 0.26738915 |
| 99 | CSNK1E | 0.26264691 |
| 100 | DAPK2 | 0.26063898 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.55471500 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.78404550 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.39564193 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.18307979 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.62889352 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.43088314 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.25366370 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.21691421 |
| 9 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.12503079 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 2.10649053 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.01522529 |
| 12 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.98730083 |
| 13 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.94726654 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.94520125 |
| 15 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.94208860 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 1.91862105 |
| 17 | DNA replication_Homo sapiens_hsa03030 | 1.80633478 |
| 18 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.75301061 |
| 19 | Mismatch repair_Homo sapiens_hsa03430 | 1.74286308 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.68739897 |
| 21 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.68477184 |
| 22 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.66346299 |
| 23 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.62699824 |
| 24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.59917946 |
| 25 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.57737938 |
| 26 | RNA transport_Homo sapiens_hsa03013 | 1.52007703 |
| 27 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.50550352 |
| 28 | Base excision repair_Homo sapiens_hsa03410 | 1.47417055 |
| 29 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.44520541 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.44304812 |
| 31 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.44144027 |
| 32 | Homologous recombination_Homo sapiens_hsa03440 | 1.41473460 |
| 33 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.38260608 |
| 34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.36161707 |
| 35 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.29900080 |
| 36 | Sulfur relay system_Homo sapiens_hsa04122 | 1.27710948 |
| 37 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.25175420 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.18925901 |
| 39 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.15594165 |
| 40 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.13923854 |
| 41 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.07706192 |
| 42 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.06946450 |
| 43 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.04060244 |
| 44 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.02694984 |
| 45 | Peroxisome_Homo sapiens_hsa04146 | 0.99651212 |
| 46 | Phototransduction_Homo sapiens_hsa04744 | 0.99199896 |
| 47 | Carbon metabolism_Homo sapiens_hsa01200 | 0.98249359 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.97599054 |
| 49 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.96440010 |
| 50 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.92179584 |
| 51 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.91434447 |
| 52 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.89781512 |
| 53 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.88329255 |
| 54 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.86486145 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.85461978 |
| 56 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.84448510 |
| 57 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.83060946 |
| 58 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.81164598 |
| 59 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.80839607 |
| 60 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.77939338 |
| 61 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.75850207 |
| 62 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.69485251 |
| 63 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.68846305 |
| 64 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.68266864 |
| 65 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.65916168 |
| 66 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.65851565 |
| 67 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.65088621 |
| 68 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.64917972 |
| 69 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.60515633 |
| 70 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.56073364 |
| 71 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52347061 |
| 72 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51971426 |
| 73 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.50615904 |
| 74 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.47664458 |
| 75 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47623394 |
| 76 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.43272757 |
| 77 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.41462885 |
| 78 | Retinol metabolism_Homo sapiens_hsa00830 | 0.40431605 |
| 79 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.39603023 |
| 80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.38149177 |
| 81 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.37906058 |
| 82 | Nicotine addiction_Homo sapiens_hsa05033 | 0.37889671 |
| 83 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.36644071 |
| 84 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.34837237 |
| 85 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.34382285 |
| 86 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.31334873 |
| 87 | Cell cycle_Homo sapiens_hsa04110 | 0.31060351 |
| 88 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.29496464 |
| 89 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.28988517 |
| 90 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.27564061 |
| 91 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.26599035 |
| 92 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.26310057 |
| 93 | Galactose metabolism_Homo sapiens_hsa00052 | 0.25108390 |
| 94 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.24870914 |
| 95 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.23983773 |
| 96 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.23870075 |
| 97 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.23629806 |
| 98 | Legionellosis_Homo sapiens_hsa05134 | 0.23241479 |
| 99 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.22689662 |
| 100 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.22315093 |

