

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.98630786 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.54878277 |
| 3 | cytidine deamination (GO:0009972) | 6.49326992 |
| 4 | cytidine metabolic process (GO:0046087) | 6.49326992 |
| 5 | cytidine catabolic process (GO:0006216) | 6.49326992 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.93240675 |
| 7 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.14742705 |
| 8 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.78066409 |
| 9 | signal peptide processing (GO:0006465) | 4.75141732 |
| 10 | purine-containing compound salvage (GO:0043101) | 4.65201391 |
| 11 | activated T cell proliferation (GO:0050798) | 4.44067457 |
| 12 | rRNA modification (GO:0000154) | 4.17098303 |
| 13 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.06964164 |
| 14 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.03191612 |
| 15 | ATP synthesis coupled proton transport (GO:0015986) | 4.03191612 |
| 16 | IMP biosynthetic process (GO:0006188) | 3.99983715 |
| 17 | peptidyl-histidine modification (GO:0018202) | 3.85188797 |
| 18 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.79773696 |
| 19 | regulation of chronic inflammatory response (GO:0002676) | 3.79405276 |
| 20 | purine nucleotide salvage (GO:0032261) | 3.79031507 |
| 21 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.73336394 |
| 22 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.73336394 |
| 23 | protein neddylation (GO:0045116) | 3.67103313 |
| 24 | regulation of activation of Janus kinase activity (GO:0010533) | 3.61035320 |
| 25 | adenosine metabolic process (GO:0046085) | 3.57230163 |
| 26 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.56929759 |
| 27 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.56639197 |
| 28 | organic cation transport (GO:0015695) | 3.52794903 |
| 29 | cullin deneddylation (GO:0010388) | 3.48446638 |
| 30 | inner mitochondrial membrane organization (GO:0007007) | 3.47656335 |
| 31 | iron-sulfur cluster assembly (GO:0016226) | 3.47557797 |
| 32 | metallo-sulfur cluster assembly (GO:0031163) | 3.47557797 |
| 33 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.40637411 |
| 34 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.34742918 |
| 35 | mast cell degranulation (GO:0043303) | 3.32449395 |
| 36 | mast cell activation involved in immune response (GO:0002279) | 3.32449395 |
| 37 | cytolysis (GO:0019835) | 3.32071192 |
| 38 | nucleobase biosynthetic process (GO:0046112) | 3.30661278 |
| 39 | purine nucleobase biosynthetic process (GO:0009113) | 3.29504366 |
| 40 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.22754410 |
| 41 | protein deneddylation (GO:0000338) | 3.21589729 |
| 42 | proteasome assembly (GO:0043248) | 3.19453354 |
| 43 | chaperone-mediated protein transport (GO:0072321) | 3.19203387 |
| 44 | GPI anchor metabolic process (GO:0006505) | 3.15278174 |
| 45 | rRNA methylation (GO:0031167) | 3.15173968 |
| 46 | negative regulation by host of viral transcription (GO:0043922) | 3.12938471 |
| 47 | GPI anchor biosynthetic process (GO:0006506) | 3.10526444 |
| 48 | negative regulation of T cell apoptotic process (GO:0070233) | 3.09788274 |
| 49 | positive regulation of translational initiation (GO:0045948) | 3.09036145 |
| 50 | piRNA metabolic process (GO:0034587) | 3.09017399 |
| 51 | urate metabolic process (GO:0046415) | 3.07864991 |
| 52 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 3.00881804 |
| 53 | serotonin receptor signaling pathway (GO:0007210) | 3.00591380 |
| 54 | respiratory chain complex IV assembly (GO:0008535) | 2.99340838 |
| 55 | regulation of meiosis I (GO:0060631) | 2.99132935 |
| 56 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.97149637 |
| 57 | nucleotide salvage (GO:0043173) | 2.97118941 |
| 58 | GMP metabolic process (GO:0046037) | 2.96019993 |
| 59 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.94987711 |
| 60 | IMP metabolic process (GO:0046040) | 2.92071765 |
| 61 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.90701803 |
| 62 | negative regulation of telomere maintenance (GO:0032205) | 2.86620145 |
| 63 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.86449141 |
| 64 | regulation of cellular amine metabolic process (GO:0033238) | 2.85121634 |
| 65 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 2.80692262 |
| 66 | behavioral response to nicotine (GO:0035095) | 2.80096688 |
| 67 | protoporphyrinogen IX biosynthetic process (GO:0006782) | 2.80088068 |
| 68 | intracellular protein transmembrane import (GO:0044743) | 2.79671884 |
| 69 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.78049419 |
| 70 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.78049419 |
| 71 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.78049419 |
| 72 | protein-cofactor linkage (GO:0018065) | 2.76648290 |
| 73 | positive regulation of interleukin-8 secretion (GO:2000484) | 2.76452544 |
| 74 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.75891689 |
| 75 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.75891689 |
| 76 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.71087145 |
| 77 | electron transport chain (GO:0022900) | 2.70203871 |
| 78 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.69404693 |
| 79 | negative regulation of viral genome replication (GO:0045071) | 2.69269835 |
| 80 | positive regulation of defense response to virus by host (GO:0002230) | 2.69018224 |
| 81 | regulation of interleukin-8 secretion (GO:2000482) | 2.68361928 |
| 82 | leukotriene biosynthetic process (GO:0019370) | 2.67679726 |
| 83 | tRNA modification (GO:0006400) | 2.67623467 |
| 84 | cellular ketone body metabolic process (GO:0046950) | 2.67038063 |
| 85 | respiratory electron transport chain (GO:0022904) | 2.65685886 |
| 86 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.63610748 |
| 87 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.63610748 |
| 88 | eosinophil chemotaxis (GO:0048245) | 2.62735461 |
| 89 | cytochrome complex assembly (GO:0017004) | 2.62647748 |
| 90 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.60466855 |
| 91 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.60315758 |
| 92 | tRNA processing (GO:0008033) | 2.59211759 |
| 93 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.59059757 |
| 94 | protein homotrimerization (GO:0070207) | 2.57721385 |
| 95 | protein complex biogenesis (GO:0070271) | 2.56735152 |
| 96 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.55588042 |
| 97 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.55456580 |
| 98 | negative regulation of ligase activity (GO:0051352) | 2.55456580 |
| 99 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.55055547 |
| 100 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.53978252 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.41070645 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.80899089 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.64364552 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.38589417 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.21182229 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.16700066 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.99313029 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.91713168 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.91496012 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.80062333 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.73332910 |
| 12 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.68026241 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.49359634 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.48173733 |
| 15 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.42163326 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.27736393 |
| 17 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.19100860 |
| 18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.13254777 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.02561310 |
| 20 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.96899710 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.95725462 |
| 22 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.89635383 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.84522289 |
| 24 | GATA1_22025678_ChIP-Seq_K562_Human | 1.83849582 |
| 25 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.83316407 |
| 26 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.83015756 |
| 27 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.81638839 |
| 28 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.76474119 |
| 29 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.76182074 |
| 30 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.71392531 |
| 31 | EWS_26573619_Chip-Seq_HEK293_Human | 1.69716937 |
| 32 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.66449881 |
| 33 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.59028433 |
| 34 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.57607357 |
| 35 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.55358015 |
| 36 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.54980229 |
| 37 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.53060847 |
| 38 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.52687930 |
| 39 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.47293157 |
| 40 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.47174316 |
| 41 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.46671222 |
| 42 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.45071475 |
| 43 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.41869235 |
| 44 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.41564214 |
| 45 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.39903575 |
| 46 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.37470830 |
| 47 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.37011744 |
| 48 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.34233281 |
| 49 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.33438448 |
| 50 | AR_20517297_ChIP-Seq_VCAP_Human | 1.33203983 |
| 51 | P300_19829295_ChIP-Seq_ESCs_Human | 1.32925169 |
| 52 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.30988051 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.27438359 |
| 54 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.27438359 |
| 55 | GATA3_26560356_Chip-Seq_TH2_Human | 1.26293157 |
| 56 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.25172352 |
| 57 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.23988327 |
| 58 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.20693730 |
| 59 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.19742619 |
| 60 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.19256449 |
| 61 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.19038718 |
| 62 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.19038718 |
| 63 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.18131577 |
| 64 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.17763418 |
| 65 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.16418476 |
| 66 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.16418476 |
| 67 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.16087048 |
| 68 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.11836336 |
| 69 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.11387579 |
| 70 | MYB_26560356_Chip-Seq_TH2_Human | 1.10295095 |
| 71 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.10283137 |
| 72 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.07240861 |
| 73 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.03471883 |
| 74 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.01466544 |
| 75 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.01339038 |
| 76 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.01109989 |
| 77 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.98795563 |
| 78 | GATA3_26560356_Chip-Seq_TH1_Human | 0.97560610 |
| 79 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.96829137 |
| 80 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.95209758 |
| 81 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.92888261 |
| 82 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92347966 |
| 83 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.92256139 |
| 84 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.92172489 |
| 85 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.91955538 |
| 86 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.91603950 |
| 87 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.90304535 |
| 88 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89181838 |
| 89 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.88837033 |
| 90 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.88472724 |
| 91 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.88348871 |
| 92 | NCOR_22424771_ChIP-Seq_293T_Human | 0.88263863 |
| 93 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.88185506 |
| 94 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.86919233 |
| 95 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.86271067 |
| 96 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.86251865 |
| 97 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.85667849 |
| 98 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.85461658 |
| 99 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.85071864 |
| 100 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.84560007 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.24772396 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.36743804 |
| 3 | MP0003195_calcinosis | 3.20804978 |
| 4 | MP0004147_increased_porphyrin_level | 3.02400101 |
| 5 | MP0002254_reproductive_system_inflammat | 3.00804301 |
| 6 | MP0003763_abnormal_thymus_physiology | 2.62290571 |
| 7 | MP0002876_abnormal_thyroid_physiology | 2.52667753 |
| 8 | MP0009697_abnormal_copulation | 2.45311574 |
| 9 | MP0002102_abnormal_ear_morphology | 2.41017916 |
| 10 | MP0003693_abnormal_embryo_hatching | 2.35581099 |
| 11 | MP0002736_abnormal_nociception_after | 2.26549514 |
| 12 | MP0001835_abnormal_antigen_presentation | 2.20541296 |
| 13 | MP0009785_altered_susceptibility_to | 2.04084527 |
| 14 | MP0002090_abnormal_vision | 1.92651875 |
| 15 | MP0000569_abnormal_digit_pigmentation | 1.87179878 |
| 16 | MP0005645_abnormal_hypothalamus_physiol | 1.84760636 |
| 17 | MP0002148_abnormal_hypersensitivity_rea | 1.84591002 |
| 18 | MP0003436_decreased_susceptibility_to | 1.79082801 |
| 19 | MP0002166_altered_tumor_susceptibility | 1.76460347 |
| 20 | MP0001873_stomach_inflammation | 1.71604057 |
| 21 | MP0008872_abnormal_physiological_respon | 1.68145265 |
| 22 | MP0005084_abnormal_gallbladder_morpholo | 1.68088095 |
| 23 | MP0006072_abnormal_retinal_apoptosis | 1.66230605 |
| 24 | MP0008058_abnormal_DNA_repair | 1.66059153 |
| 25 | MP0003567_abnormal_fetal_cardiomyocyte | 1.65906906 |
| 26 | MP0008995_early_reproductive_senescence | 1.60641288 |
| 27 | MP0006035_abnormal_mitochondrial_morpho | 1.58162111 |
| 28 | MP0005387_immune_system_phenotype | 1.53717758 |
| 29 | MP0001790_abnormal_immune_system | 1.53717758 |
| 30 | MP0001905_abnormal_dopamine_level | 1.51117951 |
| 31 | MP0002006_tumorigenesis | 1.47248465 |
| 32 | MP0003186_abnormal_redox_activity | 1.44253266 |
| 33 | MP0005377_hearing/vestibular/ear_phenot | 1.41922760 |
| 34 | MP0003878_abnormal_ear_physiology | 1.41922760 |
| 35 | MP0001919_abnormal_reproductive_system | 1.40219090 |
| 36 | MP0001968_abnormal_touch/_nociception | 1.40143166 |
| 37 | MP0003718_maternal_effect | 1.36817206 |
| 38 | MP0003866_abnormal_defecation | 1.36190188 |
| 39 | MP0002138_abnormal_hepatobiliary_system | 1.34611701 |
| 40 | MP0005253_abnormal_eye_physiology | 1.34041576 |
| 41 | MP0000372_irregular_coat_pigmentation | 1.33836783 |
| 42 | MP0001188_hyperpigmentation | 1.33330458 |
| 43 | MP0006036_abnormal_mitochondrial_physio | 1.33038045 |
| 44 | MP0005551_abnormal_eye_electrophysiolog | 1.32117937 |
| 45 | MP0005000_abnormal_immune_tolerance | 1.31029269 |
| 46 | MP0005310_abnormal_salivary_gland | 1.30385996 |
| 47 | MP0002139_abnormal_hepatobiliary_system | 1.26024730 |
| 48 | MP0004742_abnormal_vestibular_system | 1.22898732 |
| 49 | MP0005647_abnormal_sex_gland | 1.21370831 |
| 50 | MP0010094_abnormal_chromosome_stability | 1.19904403 |
| 51 | MP0010386_abnormal_urinary_bladder | 1.19765294 |
| 52 | MP0003786_premature_aging | 1.19471039 |
| 53 | MP0009333_abnormal_splenocyte_physiolog | 1.18574001 |
| 54 | MP0005646_abnormal_pituitary_gland | 1.17974580 |
| 55 | MP0005332_abnormal_amino_acid | 1.16215463 |
| 56 | MP0003011_delayed_dark_adaptation | 1.14241394 |
| 57 | MP0000371_diluted_coat_color | 1.13376516 |
| 58 | MP0005636_abnormal_mineral_homeostasis | 1.13002874 |
| 59 | MP0003787_abnormal_imprinting | 1.10514767 |
| 60 | MP0005085_abnormal_gallbladder_physiolo | 1.10479520 |
| 61 | MP0002638_abnormal_pupillary_reflex | 1.10176931 |
| 62 | MP0002420_abnormal_adaptive_immunity | 1.08724357 |
| 63 | MP0001819_abnormal_immune_cell | 1.06260807 |
| 64 | MP0001727_abnormal_embryo_implantation | 1.04158202 |
| 65 | MP0001501_abnormal_sleep_pattern | 1.02336031 |
| 66 | MP0003950_abnormal_plasma_membrane | 1.00247541 |
| 67 | MP0003724_increased_susceptibility_to | 0.99748183 |
| 68 | MP0001800_abnormal_humoral_immune | 0.98654158 |
| 69 | MP0005410_abnormal_fertilization | 0.96690457 |
| 70 | MP0002277_abnormal_respiratory_mucosa | 0.95036357 |
| 71 | MP0002938_white_spotting | 0.93350271 |
| 72 | MP0006276_abnormal_autonomic_nervous | 0.92402451 |
| 73 | MP0009764_decreased_sensitivity_to | 0.92017920 |
| 74 | MP0002064_seizures | 0.90937542 |
| 75 | MP0005365_abnormal_bile_salt | 0.90770803 |
| 76 | MP0002095_abnormal_skin_pigmentation | 0.90710763 |
| 77 | MP0002723_abnormal_immune_serum | 0.89707650 |
| 78 | MP0002210_abnormal_sex_determination | 0.88424537 |
| 79 | MP0005389_reproductive_system_phenotype | 0.87942614 |
| 80 | MP0000015_abnormal_ear_pigmentation | 0.86302074 |
| 81 | MP0005075_abnormal_melanosome_morpholog | 0.85002535 |
| 82 | MP0004957_abnormal_blastocyst_morpholog | 0.82845974 |
| 83 | MP0004215_abnormal_myocardial_fiber | 0.82205972 |
| 84 | MP0001984_abnormal_olfaction | 0.81655461 |
| 85 | MP0009745_abnormal_behavioral_response | 0.81567348 |
| 86 | MP0003806_abnormal_nucleotide_metabolis | 0.81389496 |
| 87 | MP0001970_abnormal_pain_threshold | 0.81339826 |
| 88 | MP0004142_abnormal_muscle_tone | 0.81313688 |
| 89 | MP0000685_abnormal_immune_system | 0.80353663 |
| 90 | MP0000358_abnormal_cell_content/ | 0.80145767 |
| 91 | MP0005167_abnormal_blood-brain_barrier | 0.79350903 |
| 92 | MP0009046_muscle_twitch | 0.78914169 |
| 93 | MP0010155_abnormal_intestine_physiology | 0.78832110 |
| 94 | MP0002398_abnormal_bone_marrow | 0.76428636 |
| 95 | MP0005408_hypopigmentation | 0.75648217 |
| 96 | MP0009765_abnormal_xenobiotic_induced | 0.75541931 |
| 97 | MP0002272_abnormal_nervous_system | 0.74258945 |
| 98 | MP0000490_abnormal_crypts_of | 0.73781871 |
| 99 | MP0002163_abnormal_gland_morphology | 0.72728799 |
| 100 | MP0006082_CNS_inflammation | 0.71914532 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 7.02676512 |
| 2 | Abnormality of alanine metabolism (HP:0010916) | 7.02676512 |
| 3 | Hyperalaninemia (HP:0003348) | 7.02676512 |
| 4 | Aplastic anemia (HP:0001915) | 5.00663661 |
| 5 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 4.92516798 |
| 6 | Testicular atrophy (HP:0000029) | 4.79744165 |
| 7 | Autoimmune thrombocytopenia (HP:0001973) | 4.55660431 |
| 8 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 4.55192903 |
| 9 | Autoimmune hemolytic anemia (HP:0001890) | 4.27122751 |
| 10 | Visual hallucinations (HP:0002367) | 4.05498532 |
| 11 | Increased cerebral lipofuscin (HP:0011813) | 3.95251991 |
| 12 | Dyschromatopsia (HP:0007641) | 3.57113694 |
| 13 | Methylmalonic acidemia (HP:0002912) | 3.44474028 |
| 14 | Central scotoma (HP:0000603) | 3.11753394 |
| 15 | Acute necrotizing encephalopathy (HP:0006965) | 3.10999696 |
| 16 | Tetraparesis (HP:0002273) | 3.09167832 |
| 17 | 3-Methylglutaconic aciduria (HP:0003535) | 3.08987895 |
| 18 | Increased CSF lactate (HP:0002490) | 3.02414957 |
| 19 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.94325711 |
| 20 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.94325711 |
| 21 | Spastic diplegia (HP:0001264) | 2.90398981 |
| 22 | Abnormality of T cell physiology (HP:0011840) | 2.88715302 |
| 23 | Methylmalonic aciduria (HP:0012120) | 2.86207204 |
| 24 | Renal cortical cysts (HP:0000803) | 2.80446925 |
| 25 | Abnormality of serum amino acid levels (HP:0003112) | 2.73848951 |
| 26 | Molar tooth sign on MRI (HP:0002419) | 2.73260748 |
| 27 | Abnormality of midbrain morphology (HP:0002418) | 2.73260748 |
| 28 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.72857335 |
| 29 | Mitochondrial inheritance (HP:0001427) | 2.71826389 |
| 30 | Abnormality of T cells (HP:0002843) | 2.69987080 |
| 31 | Hypoproteinemia (HP:0003075) | 2.65066212 |
| 32 | Cerebral palsy (HP:0100021) | 2.63651006 |
| 33 | Short tibia (HP:0005736) | 2.61502605 |
| 34 | Megaloblastic anemia (HP:0001889) | 2.60499229 |
| 35 | Increased serum lactate (HP:0002151) | 2.56944126 |
| 36 | Hepatocellular necrosis (HP:0001404) | 2.55362145 |
| 37 | Progressive macrocephaly (HP:0004481) | 2.55157333 |
| 38 | Acute encephalopathy (HP:0006846) | 2.51064694 |
| 39 | Scotoma (HP:0000575) | 2.48707286 |
| 40 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.41522211 |
| 41 | Prostate neoplasm (HP:0100787) | 2.34297672 |
| 42 | Opisthotonus (HP:0002179) | 2.31091843 |
| 43 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.30731490 |
| 44 | Increased serum pyruvate (HP:0003542) | 2.30504967 |
| 45 | Abnormality of vitamin B metabolism (HP:0004340) | 2.29969341 |
| 46 | Hepatic necrosis (HP:0002605) | 2.29432138 |
| 47 | Hypoalbuminemia (HP:0003073) | 2.27237585 |
| 48 | Abnormal albumin level (HP:0012116) | 2.27237585 |
| 49 | Gout (HP:0001997) | 2.23273603 |
| 50 | Abolished electroretinogram (ERG) (HP:0000550) | 2.20293097 |
| 51 | Lactic acidosis (HP:0003128) | 2.18927333 |
| 52 | T lymphocytopenia (HP:0005403) | 2.18479216 |
| 53 | Abnormality of purine metabolism (HP:0004352) | 2.18345763 |
| 54 | IgG deficiency (HP:0004315) | 2.17845257 |
| 55 | Cerebral edema (HP:0002181) | 2.17215802 |
| 56 | Abnormality of the renal cortex (HP:0011035) | 2.15469614 |
| 57 | Congenital stationary night blindness (HP:0007642) | 2.10960454 |
| 58 | Abnormality of T cell number (HP:0011839) | 2.07390615 |
| 59 | Severe combined immunodeficiency (HP:0004430) | 2.05727753 |
| 60 | Recurrent viral infections (HP:0004429) | 2.04997895 |
| 61 | Cutaneous melanoma (HP:0012056) | 2.01949218 |
| 62 | Pancytopenia (HP:0001876) | 2.01561717 |
| 63 | Lethargy (HP:0001254) | 2.00791799 |
| 64 | Parakeratosis (HP:0001036) | 1.94440251 |
| 65 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.93378043 |
| 66 | Nephronophthisis (HP:0000090) | 1.86765527 |
| 67 | Thyroid-stimulating hormone excess (HP:0002925) | 1.86582398 |
| 68 | Reduced antithrombin III activity (HP:0001976) | 1.84692092 |
| 69 | Abnormality of glycolysis (HP:0004366) | 1.84644547 |
| 70 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.84236788 |
| 71 | Optic disc pallor (HP:0000543) | 1.80302485 |
| 72 | Oligomenorrhea (HP:0000876) | 1.79685556 |
| 73 | Respiratory failure (HP:0002878) | 1.78996999 |
| 74 | Dicarboxylic aciduria (HP:0003215) | 1.78201384 |
| 75 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.78201384 |
| 76 | Microvesicular hepatic steatosis (HP:0001414) | 1.77392012 |
| 77 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.75942098 |
| 78 | Increased hepatocellular lipid droplets (HP:0006565) | 1.70854883 |
| 79 | Constricted visual fields (HP:0001133) | 1.70546286 |
| 80 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.70416675 |
| 81 | Hypomagnesemia (HP:0002917) | 1.70088558 |
| 82 | Choreoathetosis (HP:0001266) | 1.69482731 |
| 83 | Prominent metopic ridge (HP:0005487) | 1.67322114 |
| 84 | Type I transferrin isoform profile (HP:0003642) | 1.67043376 |
| 85 | Abnormality of the prostate (HP:0008775) | 1.65307143 |
| 86 | Poor suck (HP:0002033) | 1.65002011 |
| 87 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.64584118 |
| 88 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.64233751 |
| 89 | Abnormality of homocysteine metabolism (HP:0010919) | 1.64093270 |
| 90 | Homocystinuria (HP:0002156) | 1.64093270 |
| 91 | Chronic bronchitis (HP:0004469) | 1.63810996 |
| 92 | Abnormality of methionine metabolism (HP:0010901) | 1.63768461 |
| 93 | Type 2 muscle fiber atrophy (HP:0003554) | 1.62930217 |
| 94 | Palpitations (HP:0001962) | 1.62735532 |
| 95 | Microretrognathia (HP:0000308) | 1.61833084 |
| 96 | Asplenia (HP:0001746) | 1.61728789 |
| 97 | Hypobetalipoproteinemia (HP:0003563) | 1.60911712 |
| 98 | Cortical visual impairment (HP:0100704) | 1.59213511 |
| 99 | Medial flaring of the eyebrow (HP:0010747) | 1.57824865 |
| 100 | Amniotic constriction ring (HP:0009775) | 1.57540608 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 4.46825751 |
| 2 | TESK2 | 3.96233714 |
| 3 | NEK1 | 2.95257486 |
| 4 | ZAK | 2.83630777 |
| 5 | TXK | 2.68438726 |
| 6 | TSSK6 | 2.27653163 |
| 7 | ADRBK2 | 2.22205152 |
| 8 | DAPK2 | 2.17423207 |
| 9 | MAP3K12 | 2.17106190 |
| 10 | NUAK1 | 2.15323686 |
| 11 | MST4 | 2.01536183 |
| 12 | INSRR | 1.99284358 |
| 13 | TLK1 | 1.94385195 |
| 14 | BMPR2 | 1.91736970 |
| 15 | KDR | 1.88664914 |
| 16 | BUB1 | 1.88332141 |
| 17 | PDK2 | 1.80299427 |
| 18 | BCKDK | 1.78943198 |
| 19 | WNK4 | 1.67588418 |
| 20 | PNCK | 1.63973505 |
| 21 | MAP4K1 | 1.61248518 |
| 22 | GRK1 | 1.50957850 |
| 23 | TNIK | 1.45057916 |
| 24 | TAOK3 | 1.36645425 |
| 25 | LATS1 | 1.32785298 |
| 26 | MYLK | 1.30031732 |
| 27 | VRK2 | 1.29695800 |
| 28 | MAP3K11 | 1.29061282 |
| 29 | IKBKB | 1.20908177 |
| 30 | ACVR1B | 1.20618045 |
| 31 | TESK1 | 1.18404588 |
| 32 | FRK | 1.17211336 |
| 33 | PRKG2 | 1.12838902 |
| 34 | LIMK1 | 1.08780227 |
| 35 | STK16 | 1.08668799 |
| 36 | TAF1 | 1.05709375 |
| 37 | WNK3 | 1.04476458 |
| 38 | CHEK2 | 1.03404548 |
| 39 | DAPK1 | 1.00371217 |
| 40 | VRK1 | 0.98585399 |
| 41 | PAK3 | 0.93578497 |
| 42 | NME1 | 0.93517304 |
| 43 | PASK | 0.89055502 |
| 44 | WEE1 | 0.85425030 |
| 45 | PBK | 0.84295246 |
| 46 | CAMKK2 | 0.83546001 |
| 47 | BMPR1B | 0.81619087 |
| 48 | FES | 0.81483783 |
| 49 | DYRK2 | 0.81200857 |
| 50 | CAMK2D | 0.79757201 |
| 51 | TRPM7 | 0.75443166 |
| 52 | CDK8 | 0.71317564 |
| 53 | CDC7 | 0.70677611 |
| 54 | CSNK1A1 | 0.67976255 |
| 55 | PHKG1 | 0.67480923 |
| 56 | PHKG2 | 0.67480923 |
| 57 | TEC | 0.67426795 |
| 58 | ERBB3 | 0.65801271 |
| 59 | PIK3CG | 0.64333719 |
| 60 | ITK | 0.63638474 |
| 61 | KIT | 0.62769059 |
| 62 | EIF2AK3 | 0.62605577 |
| 63 | CDK19 | 0.60676305 |
| 64 | CSNK1A1L | 0.59856048 |
| 65 | STK39 | 0.59422565 |
| 66 | PLK3 | 0.59255615 |
| 67 | AURKA | 0.59186966 |
| 68 | MAPK13 | 0.58755345 |
| 69 | CASK | 0.58751161 |
| 70 | MAP2K6 | 0.58433758 |
| 71 | OXSR1 | 0.57472924 |
| 72 | CAMK2A | 0.57383568 |
| 73 | GRK7 | 0.57236703 |
| 74 | EIF2AK1 | 0.56939655 |
| 75 | AURKB | 0.55947987 |
| 76 | LCK | 0.55462561 |
| 77 | FGFR1 | 0.54779711 |
| 78 | CAMK2G | 0.54677010 |
| 79 | PIM1 | 0.54493963 |
| 80 | IKBKE | 0.54343956 |
| 81 | CSNK2A1 | 0.53542732 |
| 82 | GRK6 | 0.53044807 |
| 83 | SYK | 0.51611297 |
| 84 | PRKCQ | 0.51371642 |
| 85 | TYRO3 | 0.49424204 |
| 86 | PRKG1 | 0.49270611 |
| 87 | TRIM28 | 0.48344161 |
| 88 | RPS6KB1 | 0.48032443 |
| 89 | LYN | 0.47904488 |
| 90 | PRKCE | 0.47609493 |
| 91 | CSNK1G3 | 0.47595144 |
| 92 | STK3 | 0.47421012 |
| 93 | BRSK1 | 0.47104874 |
| 94 | PRKACA | 0.46703168 |
| 95 | CSNK2A2 | 0.46401290 |
| 96 | CSNK1G2 | 0.44746880 |
| 97 | ZAP70 | 0.44259994 |
| 98 | OBSCN | 0.42039709 |
| 99 | MAP2K7 | 0.40559881 |
| 100 | PRKCA | 0.40405970 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.00376856 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.98347940 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.02072877 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.64354321 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.34943187 |
| 6 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.34153741 |
| 7 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.31409220 |
| 8 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.06381616 |
| 9 | RNA degradation_Homo sapiens_hsa03018 | 2.05582144 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.00092302 |
| 11 | Mismatch repair_Homo sapiens_hsa03430 | 1.78903033 |
| 12 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.77950095 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.77217213 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.74396939 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.67201654 |
| 16 | Ribosome_Homo sapiens_hsa03010 | 1.66769356 |
| 17 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.64365586 |
| 18 | Alzheimers disease_Homo sapiens_hsa05010 | 1.60090233 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.59555450 |
| 20 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.54875755 |
| 21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.53346797 |
| 22 | Homologous recombination_Homo sapiens_hsa03440 | 1.51784122 |
| 23 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.51072265 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.44883963 |
| 25 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.42690235 |
| 26 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.40695073 |
| 27 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.40556438 |
| 28 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.39245052 |
| 29 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.38767675 |
| 30 | Spliceosome_Homo sapiens_hsa03040 | 1.38304422 |
| 31 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.32473096 |
| 32 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.29945841 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 1.27344740 |
| 34 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.26741549 |
| 35 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.24674596 |
| 36 | Phototransduction_Homo sapiens_hsa04744 | 1.23089854 |
| 37 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.18405685 |
| 38 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.17111351 |
| 39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.16358957 |
| 40 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.15444179 |
| 41 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.13423382 |
| 42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.11511047 |
| 43 | DNA replication_Homo sapiens_hsa03030 | 1.11438222 |
| 44 | Base excision repair_Homo sapiens_hsa03410 | 1.07977387 |
| 45 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.07405837 |
| 46 | Allograft rejection_Homo sapiens_hsa05330 | 1.06213285 |
| 47 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.02785922 |
| 48 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.01028013 |
| 49 | Asthma_Homo sapiens_hsa05310 | 1.00099632 |
| 50 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.97548684 |
| 51 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.96090632 |
| 52 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.92628689 |
| 53 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.92533154 |
| 54 | RNA transport_Homo sapiens_hsa03013 | 0.91725835 |
| 55 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.88696365 |
| 56 | Peroxisome_Homo sapiens_hsa04146 | 0.87205379 |
| 57 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.86684844 |
| 58 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.86198507 |
| 59 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.83533169 |
| 60 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.83216051 |
| 61 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.79478412 |
| 62 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.77647539 |
| 63 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.77063224 |
| 64 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.74203677 |
| 65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.73634301 |
| 66 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.72216786 |
| 67 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.70453131 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.69553183 |
| 69 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.69174297 |
| 70 | Retinol metabolism_Homo sapiens_hsa00830 | 0.68994242 |
| 71 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.66670330 |
| 72 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.65663638 |
| 73 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.65401505 |
| 74 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.64964748 |
| 75 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.62384641 |
| 76 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.56310908 |
| 77 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.55609668 |
| 78 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.54771371 |
| 79 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.52906042 |
| 80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.51174040 |
| 81 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.50079945 |
| 82 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.50055542 |
| 83 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48767439 |
| 84 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.48303869 |
| 85 | Circadian rhythm_Homo sapiens_hsa04710 | 0.46854563 |
| 86 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.45033075 |
| 87 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.40676890 |
| 88 | Legionellosis_Homo sapiens_hsa05134 | 0.40049814 |
| 89 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.38980537 |
| 90 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.38878770 |
| 91 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.36181370 |
| 92 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.34686219 |
| 93 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.34453350 |
| 94 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.34360809 |
| 95 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.34002939 |
| 96 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.33418424 |
| 97 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.31434718 |
| 98 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.31246624 |
| 99 | ABC transporters_Homo sapiens_hsa02010 | 0.30725314 |
| 100 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.29286335 |

