MRPL47

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.70078268
2energy coupled proton transport, down electrochemical gradient (GO:0015985)6.39244638
3ATP synthesis coupled proton transport (GO:0015986)6.39244638
4ribosomal large subunit biogenesis (GO:0042273)5.41876760
5viral transcription (GO:0019083)5.28798002
6mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.20976783
7translational termination (GO:0006415)5.20457538
8ribosomal small subunit biogenesis (GO:0042274)5.19699426
9proteasome assembly (GO:0043248)5.01721976
10maturation of SSU-rRNA (GO:0030490)4.95562005
11respiratory electron transport chain (GO:0022904)4.87851402
12electron transport chain (GO:0022900)4.76642513
13establishment of protein localization to mitochondrial membrane (GO:0090151)4.72981447
14ribosomal small subunit assembly (GO:0000028)4.62420792
15cotranslational protein targeting to membrane (GO:0006613)4.52448932
16SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.52092312
17translational elongation (GO:0006414)4.50838766
18cullin deneddylation (GO:0010388)4.46939699
19protein targeting to ER (GO:0045047)4.45986034
20regulation of mitochondrial translation (GO:0070129)4.32313322
21mitochondrial respiratory chain complex I assembly (GO:0032981)4.30359499
22NADH dehydrogenase complex assembly (GO:0010257)4.30359499
23mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.30359499
24translational initiation (GO:0006413)4.25261670
25establishment of protein localization to endoplasmic reticulum (GO:0072599)4.24421718
26protein localization to endoplasmic reticulum (GO:0070972)4.23445920
27GTP biosynthetic process (GO:0006183)4.22691834
28cellular protein complex disassembly (GO:0043624)4.19552167
29transcription elongation from RNA polymerase III promoter (GO:0006385)4.18582010
30termination of RNA polymerase III transcription (GO:0006386)4.18582010
31protein deneddylation (GO:0000338)4.12531615
32ribonucleoprotein complex biogenesis (GO:0022613)4.12205333
33* translation (GO:0006412)4.06306838
34protein complex biogenesis (GO:0070271)4.06198971
35viral life cycle (GO:0019058)4.05236885
36negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.05082381
37nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.01636661
387-methylguanosine mRNA capping (GO:0006370)4.01235757
39RNA capping (GO:0036260)3.97411757
407-methylguanosine RNA capping (GO:0009452)3.97411757
41ribosome assembly (GO:0042255)3.96614158
42chaperone-mediated protein transport (GO:0072321)3.96193105
43protein neddylation (GO:0045116)3.91566505
44spliceosomal snRNP assembly (GO:0000387)3.91389983
45DNA double-strand break processing (GO:0000729)3.88561739
46mitochondrial respiratory chain complex assembly (GO:0033108)3.87854914
47cellular component biogenesis (GO:0044085)3.85918243
48establishment of integrated proviral latency (GO:0075713)3.85857686
49UTP biosynthetic process (GO:0006228)3.83918521
50DNA deamination (GO:0045006)3.80622487
51guanosine-containing compound biosynthetic process (GO:1901070)3.77120190
52rRNA modification (GO:0000154)3.75459834
53negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.74658730
54negative regulation of ligase activity (GO:0051352)3.74658730
55CENP-A containing nucleosome assembly (GO:0034080)3.74323531
56positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.74286789
57oxidative phosphorylation (GO:0006119)3.70315306
58regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.69916267
59respiratory chain complex IV assembly (GO:0008535)3.69533755
60rRNA processing (GO:0006364)3.68333255
61transcription elongation from RNA polymerase I promoter (GO:0006362)3.66716788
62chromatin remodeling at centromere (GO:0031055)3.65641681
63anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.64395957
64protein complex disassembly (GO:0043241)3.62632089
65regulation of cellular amino acid metabolic process (GO:0006521)3.61651249
66mitotic metaphase plate congression (GO:0007080)3.59469865
67establishment of protein localization to mitochondrion (GO:0072655)3.55255667
68rRNA metabolic process (GO:0016072)3.54814864
69spliceosomal complex assembly (GO:0000245)3.54435257
70termination of RNA polymerase I transcription (GO:0006363)3.54219070
71macromolecular complex disassembly (GO:0032984)3.51177230
72DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.51068926
73protein targeting to mitochondrion (GO:0006626)3.50812661
74purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.49344158
75signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.45278974
76intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.45278974
77transcription-coupled nucleotide-excision repair (GO:0006283)3.43879037
78signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.43020648
79signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.43020648
80signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.43020648
81purine nucleoside triphosphate biosynthetic process (GO:0009145)3.42780373
82histone exchange (GO:0043486)3.41814923
83DNA damage response, detection of DNA damage (GO:0042769)3.38938593
84pseudouridine synthesis (GO:0001522)3.38636684
85signal transduction involved in DNA integrity checkpoint (GO:0072401)3.37720642
86signal transduction involved in DNA damage checkpoint (GO:0072422)3.37720642
87regulation of ubiquitin-protein transferase activity (GO:0051438)3.37493515
88maturation of 5.8S rRNA (GO:0000460)3.36705152
89signal transduction involved in cell cycle checkpoint (GO:0072395)3.34462706
90L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.33738947
91cytochrome complex assembly (GO:0017004)3.33583327
92nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.32676015
93metaphase plate congression (GO:0051310)3.31441993
94UTP metabolic process (GO:0046051)3.31364661
95DNA catabolic process, exonucleolytic (GO:0000738)3.30434115
96protein localization to mitochondrion (GO:0070585)3.30250350
97transcription from RNA polymerase I promoter (GO:0006360)3.28421891
98ATP biosynthetic process (GO:0006754)3.28387679
99establishment of viral latency (GO:0019043)3.27623302
100positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.26550636
101regulation of ligase activity (GO:0051340)3.25889196
102exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.25593364
103ribosome biogenesis (GO:0042254)3.22701147
104formation of translation preinitiation complex (GO:0001731)3.21368625
105DNA strand elongation involved in DNA replication (GO:0006271)3.20464435
106peptidyl-histidine modification (GO:0018202)3.20311799
107DNA ligation (GO:0006266)3.19608567
108transcription from mitochondrial promoter (GO:0006390)3.19567196
109DNA replication checkpoint (GO:0000076)3.18484751
110DNA strand elongation (GO:0022616)3.17829241
111telomere maintenance via semi-conservative replication (GO:0032201)3.16411117
112purine nucleobase biosynthetic process (GO:0009113)3.14916774
113nucleobase biosynthetic process (GO:0046112)3.14464334
114positive regulation of ligase activity (GO:0051351)3.14225074
115rRNA methylation (GO:0031167)3.13899664
116regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.11879265
117regulation of mitotic spindle checkpoint (GO:1903504)3.11879265
118kinetochore organization (GO:0051383)3.10734135
119tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.08429815
120RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.08429815
121telomere maintenance via recombination (GO:0000722)3.07338244
122inner mitochondrial membrane organization (GO:0007007)3.07306980
123IMP biosynthetic process (GO:0006188)3.06572522
124organelle disassembly (GO:1903008)3.04509354
125protein localization to kinetochore (GO:0034501)3.04429301
126DNA replication-independent nucleosome assembly (GO:0006336)3.03738678
127DNA replication-independent nucleosome organization (GO:0034724)3.03738678
128mitotic recombination (GO:0006312)3.03177721
129mitochondrial RNA metabolic process (GO:0000959)2.99775239
130double-strand break repair via nonhomologous end joining (GO:0006303)2.98189974
131non-recombinational repair (GO:0000726)2.98189974
132spindle checkpoint (GO:0031577)2.98114836
133amino acid activation (GO:0043038)2.96221971

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human5.03734277
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.56987366
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.52423360
4E2F7_22180533_ChIP-Seq_HELA_Human4.27356843
5* GABP_17652178_ChIP-ChIP_JURKAT_Human4.20445681
6EST1_17652178_ChIP-ChIP_JURKAT_Human4.10464762
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.91852356
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.75874140
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.70933035
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.48016917
11CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.25002099
12* HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.22884016
13EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.17522881
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.06650299
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.05786135
16* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.00599914
17* CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.96135452
18* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.91430021
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.88250123
20E2F4_17652178_ChIP-ChIP_JURKAT_Human2.84668443
21VDR_23849224_ChIP-Seq_CD4+_Human2.61482466
22DCP1A_22483619_ChIP-Seq_HELA_Human2.49292447
23XRN2_22483619_ChIP-Seq_HELA_Human2.43372564
24THAP11_20581084_ChIP-Seq_MESCs_Mouse2.31813928
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.26783441
26HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.25890553
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.24686054
28TTF2_22483619_ChIP-Seq_HELA_Human2.21002208
29FOXP3_21729870_ChIP-Seq_TREG_Human2.19770285
30ELF1_17652178_ChIP-ChIP_JURKAT_Human2.18035238
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.13581370
32* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse2.08046628
33SRF_21415370_ChIP-Seq_HL-1_Mouse2.06678641
34NELFA_20434984_ChIP-Seq_ESCs_Mouse2.05672593
35YY1_21170310_ChIP-Seq_MESCs_Mouse2.04572506
36PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.02938251
37ELK1_19687146_ChIP-ChIP_HELA_Human1.98933423
38GABP_19822575_ChIP-Seq_HepG2_Human1.88036329
39MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.81783626
40* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.81116946
41FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.75634616
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74562261
43MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.73203914
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.71169004
45FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.61164761
46POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.59394001
47* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.57008604
48FOXM1_23109430_ChIP-Seq_U2OS_Human1.55680787
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.51515139
50MYC_18940864_ChIP-ChIP_HL60_Human1.47910136
51HOXB4_20404135_ChIP-ChIP_EML_Mouse1.39546446
52PADI4_21655091_ChIP-ChIP_MCF-7_Human1.36436116
53CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.34686749
54ELK1_22589737_ChIP-Seq_MCF10A_Human1.34658717
55ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.33029423
56TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.30322036
57* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.28974965
58CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.27255823
59VDR_22108803_ChIP-Seq_LS180_Human1.24940604
60ZFX_18555785_ChIP-Seq_MESCs_Mouse1.21039138
61* AR_21909140_ChIP-Seq_LNCAP_Human1.18364517
62KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.17587457
63BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.16848211
64SOX2_18555785_ChIP-Seq_MESCs_Mouse1.16078973
65ZNF274_21170338_ChIP-Seq_K562_Hela1.14189466
66RBPJ_22232070_ChIP-Seq_NCS_Mouse1.12824542
67SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.11709445
68E2F1_21310950_ChIP-Seq_MCF-7_Human1.06480628
69IRF1_19129219_ChIP-ChIP_H3396_Human1.05616133
70TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.05541624
71NOTCH1_21737748_ChIP-Seq_TLL_Human1.01158575
72PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00838043
73KDM5A_27292631_Chip-Seq_BREAST_Human1.00322234
74POU5F1_16153702_ChIP-ChIP_HESCs_Human0.99783043
75* KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.97578975
76ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97551407
77FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.97463523
78* ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.97198738
79CIITA_25753668_ChIP-Seq_RAJI_Human0.95960008
80FUS_26573619_Chip-Seq_HEK293_Human0.94598883
81* SOX17_20123909_ChIP-Seq_XEN_Mouse0.93173921
82CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.90344610
83CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.89233968
84CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.88593538
85POU3F2_20337985_ChIP-ChIP_501MEL_Human0.87559190
86ELF5_23300383_ChIP-Seq_T47D_Human0.86140575
87CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.84903829
88TFEB_21752829_ChIP-Seq_HELA_Human0.83390958
89SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.82799843
90SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.81769193
91POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.81210265
92* SOX2_16153702_ChIP-ChIP_HESCs_Human0.80929723
93RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.78781616
94PCGF2_27294783_Chip-Seq_ESCs_Mouse0.77952514
95CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.76406677
96SOX2_18692474_ChIP-Seq_MEFs_Mouse0.75408073
97NANOG_16153702_ChIP-ChIP_HESCs_Human0.74559091
98SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.72896457
99CTCF_18555785_ChIP-Seq_MESCs_Mouse0.72781656
100NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.72201436
101E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.72107096
102SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.71758689
103EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.70764156
104TP63_19390658_ChIP-ChIP_HaCaT_Human0.70194551
105IGF1R_20145208_ChIP-Seq_DFB_Human0.69942085
106EWS_26573619_Chip-Seq_HEK293_Human0.69103231
107STAT3_1855785_ChIP-Seq_MESCs_Mouse0.69099701
108FLI1_27457419_Chip-Seq_LIVER_Mouse0.68603341
109OCT4_18692474_ChIP-Seq_MEFs_Mouse0.67902520
110TP53_22573176_ChIP-Seq_HFKS_Human0.66881498
111HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.66129934
112* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.64898234
113MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.64294721
114TAF15_26573619_Chip-Seq_HEK293_Human0.63065803
115SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.61639844
116TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.61058943
117TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.60295947

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.53592016
2MP0003693_abnormal_embryo_hatching4.24627928
3MP0004957_abnormal_blastocyst_morpholog3.38263078
4MP0001529_abnormal_vocalization3.02297048
5MP0008932_abnormal_embryonic_tissue2.89449356
6MP0010094_abnormal_chromosome_stability2.79739009
7MP0008058_abnormal_DNA_repair2.67937906
8MP0008877_abnormal_DNA_methylation2.65182167
9MP0003111_abnormal_nucleus_morphology2.63800079
10MP0003123_paternal_imprinting2.56441239
11MP0006292_abnormal_olfactory_placode2.48406741
12MP0001188_hyperpigmentation2.38425554
13MP0003718_maternal_effect2.38095246
14MP0003077_abnormal_cell_cycle2.37065260
15MP0008057_abnormal_DNA_replication2.36622536
16MP0006036_abnormal_mitochondrial_physio2.24431973
17MP0000372_irregular_coat_pigmentation2.19693630
18MP0003136_yellow_coat_color2.17751191
19MP0006035_abnormal_mitochondrial_morpho2.17618676
20MP0003646_muscle_fatigue2.06511821
21MP0003786_premature_aging1.99070264
22MP0004142_abnormal_muscle_tone1.92886397
23MP0003806_abnormal_nucleotide_metabolis1.85682093
24MP0003315_abnormal_perineum_morphology1.82768824
25MP0002638_abnormal_pupillary_reflex1.78311122
26MP0001905_abnormal_dopamine_level1.66861714
27MP0000566_synostosis1.64216163
28MP0003880_abnormal_central_pattern1.63824525
29MP0006276_abnormal_autonomic_nervous1.59747833
30MP0008007_abnormal_cellular_replicative1.47783768
31MP0010030_abnormal_orbit_morphology1.45678867
32MP0001293_anophthalmia1.38740286
33MP0009697_abnormal_copulation1.37828007
34MP0003121_genomic_imprinting1.37401533
35MP0004133_heterotaxia1.37173472
36MP0001986_abnormal_taste_sensitivity1.30841588
37MP0003186_abnormal_redox_activity1.30455774
38MP0005379_endocrine/exocrine_gland_phen1.29248484
39MP0002751_abnormal_autonomic_nervous1.28701843
40MP0002102_abnormal_ear_morphology1.28145723
41MP0001730_embryonic_growth_arrest1.27110571
42MP0001727_abnormal_embryo_implantation1.27102104
43MP0002938_white_spotting1.27079420
44MP0005423_abnormal_somatic_nervous1.25842974
45MP0004215_abnormal_myocardial_fiber1.24109629
46MP0001485_abnormal_pinna_reflex1.22026645
47MP0001764_abnormal_homeostasis1.19391298
48MP0006072_abnormal_retinal_apoptosis1.17043832
49MP0004145_abnormal_muscle_electrophysio1.14866111
50MP0005410_abnormal_fertilization1.13731987
51MP0002837_dystrophic_cardiac_calcinosis1.12822342
52MP0002210_abnormal_sex_determination1.11473283
53MP0000049_abnormal_middle_ear1.10828237
54MP0001929_abnormal_gametogenesis1.09004404
55MP0004381_abnormal_hair_follicle1.08638261
56MP0003195_calcinosis1.08364608
57MP0002090_abnormal_vision1.07723237
58MP0002736_abnormal_nociception_after1.07245228
59MP0009046_muscle_twitch1.04044247
60MP0000647_abnormal_sebaceous_gland1.03646471
61MP0003011_delayed_dark_adaptation1.03640058
62MP0002254_reproductive_system_inflammat1.02557277
63MP0002084_abnormal_developmental_patter1.00800513
64MP0005330_cardiomyopathy0.99812659
65MP0001697_abnormal_embryo_size0.99695499
66MP0003938_abnormal_ear_development0.99646120
67MP0008789_abnormal_olfactory_epithelium0.96515360
68MP0010307_abnormal_tumor_latency0.95518172
69MP0005409_darkened_coat_color0.95248746
70MP0005389_reproductive_system_phenotype0.94738681
71MP0001145_abnormal_male_reproductive0.94549101
72MP0000749_muscle_degeneration0.93598226
73MP0003137_abnormal_impulse_conducting0.93312761
74MP0004147_increased_porphyrin_level0.93271276
75MP0005253_abnormal_eye_physiology0.93208522
76MP0000358_abnormal_cell_content/0.92592293
77MP0003950_abnormal_plasma_membrane0.92227931
78MP0000350_abnormal_cell_proliferation0.92150605
79MP0004084_abnormal_cardiac_muscle0.91380319
80MP0008995_early_reproductive_senescence0.91126821
81MP0003698_abnormal_male_reproductive0.88556110
82MP0003122_maternal_imprinting0.87699988
83MP0003941_abnormal_skin_development0.87288500
84MP0005395_other_phenotype0.86150330
85MP0000653_abnormal_sex_gland0.86042981
86MP0002160_abnormal_reproductive_system0.84916458
87MP0005408_hypopigmentation0.84792194
88MP0008872_abnormal_physiological_respon0.84467406
89MP0003787_abnormal_imprinting0.83999797
90MP0001984_abnormal_olfaction0.80755535
91MP0005551_abnormal_eye_electrophysiolog0.80749193
92MP0005499_abnormal_olfactory_system0.79813499
93MP0005394_taste/olfaction_phenotype0.79813499
94MP0002822_catalepsy0.79471156
95MP0002095_abnormal_skin_pigmentation0.78787153
96MP0003221_abnormal_cardiomyocyte_apopto0.78377692
97MP0002272_abnormal_nervous_system0.77624398
98MP0001672_abnormal_embryogenesis/_devel0.76963228
99MP0005380_embryogenesis_phenotype0.76963228
100MP0000313_abnormal_cell_death0.76538471
101MP0002080_prenatal_lethality0.76142079
102MP0000026_abnormal_inner_ear0.74949415
103MP0008875_abnormal_xenobiotic_pharmacok0.74494658
104MP0002085_abnormal_embryonic_tissue0.74235476
105MP0005075_abnormal_melanosome_morpholog0.73646610
106MP0001119_abnormal_female_reproductive0.72833160
107MP0002233_abnormal_nose_morphology0.72558197
108MP0004036_abnormal_muscle_relaxation0.71739722
109MP0003890_abnormal_embryonic-extraembry0.71581318
110MP0005332_abnormal_amino_acid0.71195666
111MP0002163_abnormal_gland_morphology0.70934942
112MP0001286_abnormal_eye_development0.69190056
113MP0005451_abnormal_body_composition0.68643005
114MP0002127_abnormal_cardiovascular_syste0.68338542
115MP0005171_absent_coat_pigmentation0.68276764
116MP0001919_abnormal_reproductive_system0.68222220
117MP0002234_abnormal_pharynx_morphology0.66860717
118MP0001881_abnormal_mammary_gland0.65298828
119MP0003937_abnormal_limbs/digits/tail_de0.65236669
120MP0003984_embryonic_growth_retardation0.64792389
121MP0002752_abnormal_somatic_nervous0.64714708
122MP0003567_abnormal_fetal_cardiomyocyte0.64307139
123MP0002088_abnormal_embryonic_growth/wei0.63848065
124MP0005084_abnormal_gallbladder_morpholo0.63244915
125MP0001968_abnormal_touch/_nociception0.62492728
126MP0001661_extended_life_span0.62340203
127MP0000427_abnormal_hair_cycle0.61965095
128MP0005266_abnormal_metabolism0.60414370
129MP0009672_abnormal_birth_weight0.60186372
130MP0001440_abnormal_grooming_behavior0.60166363
131MP0004197_abnormal_fetal_growth/weight/0.59990421
132MP0004043_abnormal_pH_regulation0.59818528

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.23112885
2Abnormal mitochondria in muscle tissue (HP:0008316)5.61534523
3Mitochondrial inheritance (HP:0001427)5.55809020
4Progressive macrocephaly (HP:0004481)5.10814285
5Increased CSF lactate (HP:0002490)5.04430090
6Acute encephalopathy (HP:0006846)4.99141966
7Hepatocellular necrosis (HP:0001404)4.90452137
8Increased hepatocellular lipid droplets (HP:0006565)4.85955582
9Lipid accumulation in hepatocytes (HP:0006561)4.35170904
10Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.34309347
11Hepatic necrosis (HP:0002605)4.33997871
12Abnormality of cells of the erythroid lineage (HP:0012130)4.11155239
13Increased serum pyruvate (HP:0003542)4.00357374
14Abnormality of glycolysis (HP:0004366)4.00357374
15Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.98049597
16Reticulocytopenia (HP:0001896)3.92195547
17Exercise intolerance (HP:0003546)3.72062195
18Increased serum lactate (HP:0002151)3.71806694
19Abnormal number of erythroid precursors (HP:0012131)3.66657823
20Renal Fanconi syndrome (HP:0001994)3.66392245
21Macrocytic anemia (HP:0001972)3.65716979
22Cerebral edema (HP:0002181)3.54276756
233-Methylglutaconic aciduria (HP:0003535)3.53239973
24Increased intramyocellular lipid droplets (HP:0012240)3.41797600
25Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.39120261
26Decreased activity of mitochondrial respiratory chain (HP:0008972)3.39120261
27Respiratory failure (HP:0002878)3.38298349
28Lactic acidosis (HP:0003128)3.37385839
29Optic disc pallor (HP:0000543)3.33569406
30Exertional dyspnea (HP:0002875)3.22086981
31Breast hypoplasia (HP:0003187)3.15970564
32Abnormality of methionine metabolism (HP:0010901)3.12446699
33Birth length less than 3rd percentile (HP:0003561)3.10955046
34Leukodystrophy (HP:0002415)3.01770034
35Pallor (HP:0000980)2.87127685
36Increased muscle lipid content (HP:0009058)2.86180905
37Microvesicular hepatic steatosis (HP:0001414)2.85310870
38Cerebral hypomyelination (HP:0006808)2.83702383
39Respiratory difficulties (HP:0002880)2.78507651
40Progressive external ophthalmoplegia (HP:0000590)2.75492151
41Type I transferrin isoform profile (HP:0003642)2.74140828
42Abnormality of aspartate family amino acid metabolism (HP:0010899)2.72140402
43Degeneration of anterior horn cells (HP:0002398)2.55668645
44Abnormality of the anterior horn cell (HP:0006802)2.55668645
45Aplasia/Hypoplasia of the sacrum (HP:0008517)2.49023440
46Chromsome breakage (HP:0040012)2.48654919
47Abnormality of chromosome stability (HP:0003220)2.47636818
48Emotional lability (HP:0000712)2.47557696
49Meckel diverticulum (HP:0002245)2.45383311
50Oral leukoplakia (HP:0002745)2.43465838
51Abnormality of serum amino acid levels (HP:0003112)2.42353140
52CNS demyelination (HP:0007305)2.40496136
53Chromosomal breakage induced by crosslinking agents (HP:0003221)2.38550805
54Carpal bone hypoplasia (HP:0001498)2.38120916
55Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.36734203
56Abnormality of alanine metabolism (HP:0010916)2.36734203
57Hyperalaninemia (HP:0003348)2.36734203
58Abnormality of the ileum (HP:0001549)2.35588202
59Colon cancer (HP:0003003)2.35304608
60Abnormality of renal resorption (HP:0011038)2.34789471
61Aplasia/Hypoplasia of the uvula (HP:0010293)2.29642957
62Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.27278906
63Horseshoe kidney (HP:0000085)2.23914481
64Stenosis of the external auditory canal (HP:0000402)2.23240628
65Abnormal protein glycosylation (HP:0012346)2.22006855
66Abnormal glycosylation (HP:0012345)2.22006855
67Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.22006855
68Abnormal protein N-linked glycosylation (HP:0012347)2.22006855
69Rough bone trabeculation (HP:0100670)2.21509094
70Abnormal lung lobation (HP:0002101)2.16949581
71Neoplasm of the adrenal gland (HP:0100631)2.12039963
72Absent radius (HP:0003974)2.11954130
73Multiple enchondromatosis (HP:0005701)2.04754827
74Aplastic anemia (HP:0001915)2.03546907
75Lethargy (HP:0001254)2.01927493
76Aplasia involving forearm bones (HP:0009822)2.01048835
77Absent forearm bone (HP:0003953)2.01048835
78Hyperphosphaturia (HP:0003109)1.96868938
79Parakeratosis (HP:0001036)1.94996560
80Triphalangeal thumb (HP:0001199)1.94950156
81Aplasia/Hypoplasia involving the musculature (HP:0001460)1.94638257
82Hyperglycinemia (HP:0002154)1.93749630
83Congenital, generalized hypertrichosis (HP:0004540)1.93521333
84Hypoglycemic coma (HP:0001325)1.92527646
85Adrenal hypoplasia (HP:0000835)1.91482563
86Unsteady gait (HP:0002317)1.90921335
87Duodenal stenosis (HP:0100867)1.89472062
88Small intestinal stenosis (HP:0012848)1.89472062
89Reduced antithrombin III activity (HP:0001976)1.87833908
90Megaloblastic anemia (HP:0001889)1.86054812
91X-linked dominant inheritance (HP:0001423)1.85618149
92Abnormality of placental membranes (HP:0011409)1.85587449
93Amniotic constriction ring (HP:0009775)1.85587449
94Sparse eyelashes (HP:0000653)1.84403674
95Supernumerary spleens (HP:0009799)1.84243401
96Molar tooth sign on MRI (HP:0002419)1.83934917
97Abnormality of midbrain morphology (HP:0002418)1.83934917
98Irregular epiphyses (HP:0010582)1.82545696
99Abnormality of urine glucose concentration (HP:0011016)1.81581347
100Glycosuria (HP:0003076)1.81581347
101Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.80986427
102Patellar aplasia (HP:0006443)1.80252225
103Ependymoma (HP:0002888)1.79282822
104Pancreatic fibrosis (HP:0100732)1.78846452
105Methylmalonic aciduria (HP:0012120)1.78377992
106Abnormality of vitamin B metabolism (HP:0004340)1.77350472
107Absent thumb (HP:0009777)1.77306734
108Secondary amenorrhea (HP:0000869)1.77275672
109Abnormality of the preputium (HP:0100587)1.76630066
110Medial flaring of the eyebrow (HP:0010747)1.76558332
111CNS hypomyelination (HP:0003429)1.75724527
112Palpitations (HP:0001962)1.74478645
113Volvulus (HP:0002580)1.73846955
114Hypoplastic pelvis (HP:0008839)1.73582698
115Abnormality of the vitamin B12 metabolism (HP:0004341)1.72454415
116Abnormality of the duodenum (HP:0002246)1.72378430
117Delusions (HP:0000746)1.72186695
118Gliosis (HP:0002171)1.71857969
119Abnormality of the labia minora (HP:0012880)1.71739979
120Generalized aminoaciduria (HP:0002909)1.71275346
121Rhabdomyosarcoma (HP:0002859)1.71150267
122Microretrognathia (HP:0000308)1.68998101
123Aplasia/Hypoplasia of the patella (HP:0006498)1.68044480
124Sloping forehead (HP:0000340)1.67279123
125Abnormal pupillary function (HP:0007686)1.67036075
126Duplicated collecting system (HP:0000081)1.66905296
127Pancytopenia (HP:0001876)1.66594980
128Congenital malformation of the right heart (HP:0011723)1.65389516
129Double outlet right ventricle (HP:0001719)1.65389516
130Type 2 muscle fiber atrophy (HP:0003554)1.64490387
131Methylmalonic acidemia (HP:0002912)1.64331599
132Premature graying of hair (HP:0002216)1.64307296
133Aplasia/hypoplasia of the uterus (HP:0008684)1.63830872
134External ophthalmoplegia (HP:0000544)1.63351780
135Rectal fistula (HP:0100590)1.63338219
136Rectovaginal fistula (HP:0000143)1.63338219
137Abnormal trabecular bone morphology (HP:0100671)1.63211830
138Abnormal respiratory motile cilium morphology (HP:0005938)1.63161968
139Abnormal respiratory epithelium morphology (HP:0012253)1.63161968
140Pancreatic cysts (HP:0001737)1.62560651

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.63840943
2EIF2AK13.85326767
3STK163.73436197
4WEE13.51864862
5NME23.39069217
6SRPK13.13419110
7NME12.98766031
8VRK22.95394821
9TLK12.79139730
10PNCK2.47095964
11VRK12.29458930
12TRIM282.21437536
13EIF2AK32.14370719
14PLK41.92388036
15NUAK11.85947787
16PBK1.83709148
17MKNK11.76981515
18MKNK21.76608435
19CDC71.62874649
20MST41.60771034
21BRSK21.57110849
22TSSK61.56413637
23CASK1.54867983
24TTK1.48546705
25WNK31.43805445
26DYRK31.41550833
27PLK11.41484423
28MAP4K21.39905945
29AURKA1.38239997
30PLK31.33473039
31DYRK21.29269334
32TAF11.23351574
33TESK21.23045763
34PDK31.22046162
35PDK41.22046162
36ACVR1B1.17116412
37BRAF1.13937846
38ZAK1.13276215
39AURKB1.13140833
40MYLK1.10744285
41ERBB31.10266027
42CCNB11.10214824
43STK391.06853537
44OBSCN1.06558372
45MAP2K71.00924268
46CDK190.99501473
47PIM20.97163350
48FRK0.96286334
49BRSK10.95463433
50LIMK10.93065137
51CHEK20.92219820
52CDK70.89674794
53CDK80.87403559
54CSNK1G10.81183562
55ARAF0.80830771
56CSNK2A20.80063828
57CSNK2A10.79720984
58MUSK0.77114075
59MAP3K120.75079464
60RPS6KA50.74187207
61PAK40.73845772
62NEK20.73430859
63EIF2AK20.71742861
64NEK10.69623160
65BCKDK0.69317391
66PDK20.69248711
67CSNK1G20.69167543
68BCR0.68446917
69OXSR10.67561852
70IRAK30.66747415
71CDK30.66386614
72ATR0.65920233
73STK30.65543755
74PLK20.62731717
75GRK10.62364111
76ERBB40.61939141
77ALK0.59560037
78CLK10.58364643
79IRAK10.58242286
80AKT30.57388101
81RPS6KB20.56324233
82CSNK1A1L0.55524834
83GRK70.54708497
84TGFBR10.52623111
85CHEK10.51664917
86PAK10.51057863
87STK38L0.50680907
88ADRBK20.49663230
89TNIK0.48701040
90INSRR0.46524669
91PASK0.46125546
92EPHA20.45948272
93STK40.44716173
94DAPK30.44506806
95MAP3K40.44421321
96CAMK2B0.44207280
97PHKG20.39677547
98PHKG10.39677547
99DAPK10.39642947
100STK240.39582162
101CSNK1G30.39276307
102STK100.39150309
103ATM0.38638203
104ABL20.38239140
105PAK30.37575889
106ILK0.37157074
107CSNK1E0.36953101
108CAMK2A0.36664659
109CDK10.36259562
110YES10.36029490
111BMPR1B0.35828531
112IRAK20.35819322
113MINK10.34639130
114NEK60.34607042
115CAMK2G0.33884674
116CDK140.33398528
117PRKCI0.33354451
118UHMK10.33214663
119BMPR20.33149110
120MAPKAPK50.33053333
121PRKCE0.32990370
122CDK20.32899431
123CAMK2D0.32165874
124DMPK0.31726984
125MAPK130.31335431
126NEK90.31047133
127KDR0.29938536
128WNK40.29433444
129CSNK1A10.29222572
130FGFR10.28691313
131PRKCG0.27608347

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.07606621
2Proteasome_Homo sapiens_hsa030504.45258175
3Oxidative phosphorylation_Homo sapiens_hsa001904.38811391
4RNA polymerase_Homo sapiens_hsa030203.98467270
5Parkinsons disease_Homo sapiens_hsa050123.92236305
6Huntingtons disease_Homo sapiens_hsa050163.07006708
7DNA replication_Homo sapiens_hsa030302.95460528
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.93301054
9Mismatch repair_Homo sapiens_hsa034302.84068621
10Alzheimers disease_Homo sapiens_hsa050102.73859157
11Spliceosome_Homo sapiens_hsa030402.63598878
12Pyrimidine metabolism_Homo sapiens_hsa002402.40598597
13Nucleotide excision repair_Homo sapiens_hsa034202.37648846
14Homologous recombination_Homo sapiens_hsa034402.31778757
15Protein export_Homo sapiens_hsa030602.27516335
16Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.21671516
17RNA transport_Homo sapiens_hsa030132.11338214
18Basal transcription factors_Homo sapiens_hsa030222.05203937
19Cardiac muscle contraction_Homo sapiens_hsa042601.91055768
20Base excision repair_Homo sapiens_hsa034101.80355291
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.62635726
22Fanconi anemia pathway_Homo sapiens_hsa034601.57187372
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.49641941
24RNA degradation_Homo sapiens_hsa030181.49349986
25Purine metabolism_Homo sapiens_hsa002301.46369563
26Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.46124511
27Non-homologous end-joining_Homo sapiens_hsa034501.44866677
28Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.25464460
29Cell cycle_Homo sapiens_hsa041101.25173970
30One carbon pool by folate_Homo sapiens_hsa006701.23565612
31Vitamin B6 metabolism_Homo sapiens_hsa007501.00488972
32Selenocompound metabolism_Homo sapiens_hsa004500.95337325
33Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.94100858
34mRNA surveillance pathway_Homo sapiens_hsa030150.91682611
35Fatty acid elongation_Homo sapiens_hsa000620.91355788
36Cysteine and methionine metabolism_Homo sapiens_hsa002700.90510326
37Folate biosynthesis_Homo sapiens_hsa007900.86727101
38Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.82366501
39Pyruvate metabolism_Homo sapiens_hsa006200.78843821
40Metabolic pathways_Homo sapiens_hsa011000.76926732
41Carbon metabolism_Homo sapiens_hsa012000.76611382
42Glutathione metabolism_Homo sapiens_hsa004800.76567768
43Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.72167507
44Epstein-Barr virus infection_Homo sapiens_hsa051690.70917952
45Pentose and glucuronate interconversions_Homo sapiens_hsa000400.67834497
46Collecting duct acid secretion_Homo sapiens_hsa049660.67071357
47Systemic lupus erythematosus_Homo sapiens_hsa053220.65234717
48Sulfur relay system_Homo sapiens_hsa041220.63709322
49Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.62051246
50Phototransduction_Homo sapiens_hsa047440.61634685
51Oocyte meiosis_Homo sapiens_hsa041140.61399193
52Fatty acid metabolism_Homo sapiens_hsa012120.59571569
53Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.59521096
54Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.57638449
55Arachidonic acid metabolism_Homo sapiens_hsa005900.56323649
56Propanoate metabolism_Homo sapiens_hsa006400.55809248
57Biosynthesis of amino acids_Homo sapiens_hsa012300.55450393
58Caffeine metabolism_Homo sapiens_hsa002320.55113856
59N-Glycan biosynthesis_Homo sapiens_hsa005100.54672294
60Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54366736
61Fatty acid degradation_Homo sapiens_hsa000710.53998450
622-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.52424995
63Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.50909418
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49252571
65Nicotine addiction_Homo sapiens_hsa050330.48940698
66p53 signaling pathway_Homo sapiens_hsa041150.44837140
67Tryptophan metabolism_Homo sapiens_hsa003800.43465297
68Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.43418633
69Pentose phosphate pathway_Homo sapiens_hsa000300.43398065
70Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43238775
71Linoleic acid metabolism_Homo sapiens_hsa005910.42541503
72Regulation of autophagy_Homo sapiens_hsa041400.40787587
73Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.39670245
74Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.38773215
75Drug metabolism - other enzymes_Homo sapiens_hsa009830.37570870
76Chemical carcinogenesis_Homo sapiens_hsa052040.36202755
77Vibrio cholerae infection_Homo sapiens_hsa051100.35879756
78Vitamin digestion and absorption_Homo sapiens_hsa049770.33935062
79Alcoholism_Homo sapiens_hsa050340.33812310
80Cyanoamino acid metabolism_Homo sapiens_hsa004600.32889158
81Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.32652895
82Sulfur metabolism_Homo sapiens_hsa009200.32372829
83Ether lipid metabolism_Homo sapiens_hsa005650.32311703
84Fructose and mannose metabolism_Homo sapiens_hsa000510.30401047
85Steroid biosynthesis_Homo sapiens_hsa001000.29253658
86Primary bile acid biosynthesis_Homo sapiens_hsa001200.27919762
87Arginine and proline metabolism_Homo sapiens_hsa003300.26568544
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.26525656
89Retinol metabolism_Homo sapiens_hsa008300.25745516
90Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.23836716
91Tyrosine metabolism_Homo sapiens_hsa003500.23688332
92Sphingolipid metabolism_Homo sapiens_hsa006000.22786287
93Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.21146130
94Maturity onset diabetes of the young_Homo sapiens_hsa049500.20338845
95Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.19280110
96alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.18239348
97Serotonergic synapse_Homo sapiens_hsa047260.17296884
98SNARE interactions in vesicular transport_Homo sapiens_hsa041300.15482078
99Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.14781686
100Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.14494973
101TGF-beta signaling pathway_Homo sapiens_hsa043500.14360145
102Steroid hormone biosynthesis_Homo sapiens_hsa001400.14142702
103Mineral absorption_Homo sapiens_hsa049780.13327591
104Nitrogen metabolism_Homo sapiens_hsa009100.12847830
105Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.11239414
106Phenylalanine metabolism_Homo sapiens_hsa003600.10663370
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.10386173
108Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.09517094
109Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.07019396
110Butanoate metabolism_Homo sapiens_hsa006500.06751971
111Peroxisome_Homo sapiens_hsa041460.05732507
112Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.03921092
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.02989662
114Taste transduction_Homo sapiens_hsa047420.02516654
115beta-Alanine metabolism_Homo sapiens_hsa00410-0.0827208
116Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040-0.0708119
117Wnt signaling pathway_Homo sapiens_hsa04310-0.0675559
118Herpes simplex infection_Homo sapiens_hsa05168-0.0513930
119Autoimmune thyroid disease_Homo sapiens_hsa05320-0.0440729
120Basal cell carcinoma_Homo sapiens_hsa05217-0.0436331
121Viral carcinogenesis_Homo sapiens_hsa05203-0.0322278
122Galactose metabolism_Homo sapiens_hsa00052-0.0297701
123Drug metabolism - cytochrome P450_Homo sapiens_hsa00982-0.0224694
124Retrograde endocannabinoid signaling_Homo sapiens_hsa04723-0.0122509

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