MRPS34

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.61560932
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.83370602
3ribosomal small subunit assembly (GO:0000028)5.77553468
4viral transcription (GO:0019083)5.58252063
5translational termination (GO:0006415)5.38387954
6energy coupled proton transport, down electrochemical gradient (GO:0015985)5.33273955
7ATP synthesis coupled proton transport (GO:0015986)5.33273955
8ribosomal small subunit biogenesis (GO:0042274)5.31532604
9proteasome assembly (GO:0043248)5.04978458
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.02499240
11cotranslational protein targeting to membrane (GO:0006613)4.94307089
12protein targeting to ER (GO:0045047)4.92065859
13translational elongation (GO:0006414)4.88878311
14maturation of SSU-rRNA (GO:0030490)4.80736145
15protein localization to endoplasmic reticulum (GO:0070972)4.74205742
16establishment of protein localization to endoplasmic reticulum (GO:0072599)4.65317257
17respiratory electron transport chain (GO:0022904)4.65075611
18ribosomal large subunit biogenesis (GO:0042273)4.61160663
19mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.60643658
20electron transport chain (GO:0022900)4.54666570
21oxidative phosphorylation (GO:0006119)4.50725137
22translational initiation (GO:0006413)4.37772079
23DNA unwinding involved in DNA replication (GO:0006268)4.36512919
24protein maturation by protein folding (GO:0022417)4.30554577
25translation (GO:0006412)4.24431590
26regulation of mitochondrial translation (GO:0070129)4.21764173
27viral life cycle (GO:0019058)4.20488275
28cellular protein complex disassembly (GO:0043624)4.19323430
29peptidyl-arginine omega-N-methylation (GO:0035247)4.11259358
30termination of RNA polymerase III transcription (GO:0006386)4.00689560
31transcription elongation from RNA polymerase III promoter (GO:0006385)4.00689560
32nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.94885985
33ribosome biogenesis (GO:0042254)3.82375648
34ribonucleoprotein complex biogenesis (GO:0022613)3.81098373
35mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.80520418
36mitochondrial respiratory chain complex I assembly (GO:0032981)3.80520418
37NADH dehydrogenase complex assembly (GO:0010257)3.80520418
38metallo-sulfur cluster assembly (GO:0031163)3.79165843
39iron-sulfur cluster assembly (GO:0016226)3.79165843
40deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.78822677
41negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.74191830
42L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.72730105
43establishment of integrated proviral latency (GO:0075713)3.70877798
44histone arginine methylation (GO:0034969)3.69335209
45protein complex biogenesis (GO:0070271)3.65113807
46formation of translation preinitiation complex (GO:0001731)3.64775059
47negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.62509314
48regulation of cellular amino acid metabolic process (GO:0006521)3.61423975
49mitochondrial respiratory chain complex assembly (GO:0033108)3.60238844
50regulation of translational fidelity (GO:0006450)3.60062396
51protein complex disassembly (GO:0043241)3.59492243
52proline biosynthetic process (GO:0006561)3.58972428
53respiratory chain complex IV assembly (GO:0008535)3.58721221
54pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.55847981
55cellular component biogenesis (GO:0044085)3.55734348
56DNA replication initiation (GO:0006270)3.55532886
57establishment of protein localization to mitochondrial membrane (GO:0090151)3.55355739
58establishment of protein localization to mitochondrion (GO:0072655)3.55326680
59protein targeting to mitochondrion (GO:0006626)3.54750445
60viral mRNA export from host cell nucleus (GO:0046784)3.53965403
61L-methionine salvage (GO:0071267)3.53566755
62L-methionine biosynthetic process (GO:0071265)3.53566755
63amino acid salvage (GO:0043102)3.53566755
64pseudouridine synthesis (GO:0001522)3.49368320
65macromolecular complex disassembly (GO:0032984)3.48048686
66telomere maintenance via recombination (GO:0000722)3.41949288
67pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.41492777
68nucleobase biosynthetic process (GO:0046112)3.40338947
69guanosine-containing compound biosynthetic process (GO:1901070)3.37736103
70GTP biosynthetic process (GO:0006183)3.36436215
71DNA strand elongation involved in DNA replication (GO:0006271)3.35768028
72negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.33994338
73telomere maintenance via semi-conservative replication (GO:0032201)3.32873071
74rRNA modification (GO:0000154)3.32437134
75purine nucleobase biosynthetic process (GO:0009113)3.31611760
76negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.30453688
77negative regulation of ligase activity (GO:0051352)3.30453688
78regulation of mammary gland epithelial cell proliferation (GO:0033599)3.30183477
79positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.29689061
80inner mitochondrial membrane organization (GO:0007007)3.26495650
81pteridine-containing compound biosynthetic process (GO:0042559)3.26464646
82pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.24222838
83quinone biosynthetic process (GO:1901663)3.23494740
84ubiquinone biosynthetic process (GO:0006744)3.23494740
85DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.23037670
86glycine metabolic process (GO:0006544)3.22943223
87rRNA processing (GO:0006364)3.22645174
88protein targeting to membrane (GO:0006612)3.22583038
89peptidyl-arginine methylation (GO:0018216)3.22148914
90peptidyl-arginine N-methylation (GO:0035246)3.22148914
91protein localization to mitochondrion (GO:0070585)3.21930544
92rRNA transcription (GO:0009303)3.21859941
93antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.21799160
94ribosome assembly (GO:0042255)3.20919784
95CTP metabolic process (GO:0046036)3.20786196
96CTP biosynthetic process (GO:0006241)3.20786196
97mitotic chromosome condensation (GO:0007076)3.20770418
98pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.20142471
992-deoxyribonucleotide biosynthetic process (GO:0009265)3.19303252
100deoxyribose phosphate biosynthetic process (GO:0046385)3.19303252
101regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.19187609
102UTP biosynthetic process (GO:0006228)3.18069419
103DNA strand elongation (GO:0022616)3.17592193
104establishment of viral latency (GO:0019043)3.16880933
105intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.16443008
106signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.16443008
107UTP metabolic process (GO:0046051)3.16247622
108signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.15535304
109signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.15535304
110signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.15535304
111purine nucleoside triphosphate biosynthetic process (GO:0009145)3.14752182
112nucleobase-containing small molecule interconversion (GO:0015949)3.14418605
113GDP-mannose metabolic process (GO:0019673)3.13676464
114purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.13599201
115transcription from mitochondrial promoter (GO:0006390)3.13374324
116chaperone-mediated protein transport (GO:0072321)3.13097534
117negative regulation of RNA splicing (GO:0033119)3.12242929
118pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.12207775
119pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.11403768
120pyrimidine nucleotide catabolic process (GO:0006244)3.11072900
121L-serine metabolic process (GO:0006563)3.10993533
122L-phenylalanine metabolic process (GO:0006558)3.10192875
123erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.10192875
124folic acid metabolic process (GO:0046655)3.10035724
125signal transduction involved in DNA integrity checkpoint (GO:0072401)3.10016482
126signal transduction involved in DNA damage checkpoint (GO:0072422)3.10016482
127rRNA metabolic process (GO:0016072)3.09686582
128spliceosomal snRNP assembly (GO:0000387)3.09464904
129negative regulation of mRNA processing (GO:0050686)3.09267158
130protein deneddylation (GO:0000338)3.08641978
131mitotic recombination (GO:0006312)3.08102437
132cullin deneddylation (GO:0010388)3.08056324
133anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.07206741
134pentose-phosphate shunt (GO:0006098)3.07195200
135spliceosomal tri-snRNP complex assembly (GO:0000244)3.04064224
136DNA replication checkpoint (GO:0000076)3.02714750
137nuclear envelope reassembly (GO:0031468)3.01279368
138mitotic nuclear envelope reassembly (GO:0007084)3.01279368
139pentose metabolic process (GO:0019321)2.95283070
140protein complex localization (GO:0031503)2.91138336

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.33100671
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.13561006
3* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.92524012
4* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.79487777
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.60483067
6ETS1_20019798_ChIP-Seq_JURKAT_Human3.50968205
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.42032654
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.36624164
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.25838877
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.17708372
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.17382914
12E2F7_22180533_ChIP-Seq_HELA_Human2.95386807
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.90058704
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.69336668
15* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.69010275
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.51092313
17XRN2_22483619_ChIP-Seq_HELA_Human2.42616384
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.39546392
19PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.39525068
20ELF1_17652178_ChIP-ChIP_JURKAT_Human2.36289598
21E2F1_18555785_ChIP-Seq_MESCs_Mouse2.36108617
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.29950896
23ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.29476205
24DCP1A_22483619_ChIP-Seq_HELA_Human2.29417348
25VDR_23849224_ChIP-Seq_CD4+_Human2.27846275
26THAP11_20581084_ChIP-Seq_MESCs_Mouse2.14970898
27SRF_21415370_ChIP-Seq_HL-1_Mouse2.13350762
28PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.10460187
29YY1_21170310_ChIP-Seq_MESCs_Mouse2.09680783
30CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.08694161
31* GABP_19822575_ChIP-Seq_HepG2_Human2.06308379
32VDR_21846776_ChIP-Seq_THP-1_Human2.00542613
33NELFA_20434984_ChIP-Seq_ESCs_Mouse1.98173299
34FOXP3_21729870_ChIP-Seq_TREG_Human1.96498903
35FOXM1_23109430_ChIP-Seq_U2OS_Human1.95234353
36CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.95090826
37TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.91479654
38MYC_22102868_ChIP-Seq_BL_Human1.88369133
39CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.86813903
40TTF2_22483619_ChIP-Seq_HELA_Human1.80856437
41ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.75681161
42* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.67913905
43SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.66972467
44* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.58483933
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.57206617
46FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.55022606
47ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.52594861
48CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.48812303
49POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.47556708
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.47384942
51LXR_22292898_ChIP-Seq_THP-1_Human1.46848196
52BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.46635329
53SRY_22984422_ChIP-ChIP_TESTIS_Rat1.46182449
54E2F4_17652178_ChIP-ChIP_JURKAT_Human1.43689455
55STAT3_1855785_ChIP-Seq_MESCs_Mouse1.41706633
56CIITA_25753668_ChIP-Seq_RAJI_Human1.40675990
57NANOG_18555785_ChIP-Seq_MESCs_Mouse1.38655038
58CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.38512311
59PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38424420
60PPARA_22158963_ChIP-Seq_LIVER_Mouse1.35558366
61MYCN_18555785_ChIP-Seq_MESCs_Mouse1.33679423
62ERG_20887958_ChIP-Seq_HPC-7_Mouse1.32078002
63HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.31012378
64RXR_22158963_ChIP-Seq_LIVER_Mouse1.30058757
65CTCF_18555785_ChIP-Seq_MESCs_Mouse1.27297396
66HOXB4_20404135_ChIP-ChIP_EML_Mouse1.27284006
67RACK7_27058665_Chip-Seq_MCF-7_Human1.26896058
68CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.26200550
69ELK3_25401928_ChIP-Seq_HUVEC_Human1.24910275
70POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.21429336
71ZNF263_19887448_ChIP-Seq_K562_Human1.20847016
72MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.20462669
73ELK1_22589737_ChIP-Seq_MCF10A_Human1.19969632
74SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.19891589
75SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.19652487
76CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.17975249
77P68_20966046_ChIP-Seq_HELA_Human1.17654634
78ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.17278470
79POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16995626
80TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.16954046
81NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.16917048
82YY1_22570637_ChIP-Seq_MALME-3M_Human1.16790082
83KDM5A_27292631_Chip-Seq_BREAST_Human1.15987557
84ELK1_19687146_ChIP-ChIP_HELA_Human1.15336501
85CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.12304048
86HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.12177481
87OCT4_18692474_ChIP-Seq_MEFs_Mouse1.10222160
88TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08559771
89YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.08079973
90ESR1_15608294_ChIP-ChIP_MCF-7_Human1.07948078
91TET1_21451524_ChIP-Seq_MESCs_Mouse1.05054553
92KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.04177674
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.04013662
94FOXP1_21924763_ChIP-Seq_HESCs_Human1.03961968
95EGR1_23403033_ChIP-Seq_LIVER_Mouse1.02785811
96* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.02372233
97SA1_27219007_Chip-Seq_ERYTHROID_Human1.01859902
98KLF4_18555785_ChIP-Seq_MESCs_Mouse1.01412675
99SOX2_18692474_ChIP-Seq_MEFs_Mouse1.01396158
100CTCF_26484167_Chip-Seq_Bcells_Mouse1.01181902
101* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.99771732
102MYC_18940864_ChIP-ChIP_HL60_Human0.98597122
103SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.98325799
104ELF1_20517297_ChIP-Seq_JURKAT_Human0.98312253
105SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.97467064
106RARG_19884340_ChIP-ChIP_MEFs_Mouse0.97359859
107NOTCH1_21737748_ChIP-Seq_TLL_Human0.97134246
108EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.97128042
109KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.95827172
110* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95288077
111CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.95185524
112MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.92711261
113TBX5_21415370_ChIP-Seq_HL-1_Mouse0.89390754
114ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.88517381
115AR_21909140_ChIP-Seq_LNCAP_Human0.87340050
116DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.86666755
117E2F1_21310950_ChIP-Seq_MCF-7_Human0.86002826
118TFEB_21752829_ChIP-Seq_HELA_Human0.84516372
119* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.84077686

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis5.10151949
2MP0009379_abnormal_foot_pigmentation4.24330806
3MP0003693_abnormal_embryo_hatching3.94598773
4MP0002139_abnormal_hepatobiliary_system3.75649613
5MP0006036_abnormal_mitochondrial_physio3.62259406
6MP0003186_abnormal_redox_activity3.17823023
7MP0005360_urolithiasis3.01286865
8MP0004957_abnormal_blastocyst_morpholog2.96299861
9MP0005085_abnormal_gallbladder_physiolo2.76194474
10MP0009840_abnormal_foam_cell2.55908571
11MP0006035_abnormal_mitochondrial_morpho2.55320586
12MP0005332_abnormal_amino_acid2.46124045
13MP0008875_abnormal_xenobiotic_pharmacok2.42903979
14MP0005365_abnormal_bile_salt2.34217192
15MP0005083_abnormal_biliary_tract2.21775877
16MP0004185_abnormal_adipocyte_glucose2.17431823
17MP0003646_muscle_fatigue2.16600471
18MP0002877_abnormal_melanocyte_morpholog2.09020659
19MP0003195_calcinosis2.04998764
20MP0005501_abnormal_skin_physiology2.00880568
21MP0000350_abnormal_cell_proliferation2.00235395
22MP0002837_dystrophic_cardiac_calcinosis1.97133580
23MP0000678_abnormal_parathyroid_gland1.95217860
24MP0001764_abnormal_homeostasis1.94844256
25MP0010030_abnormal_orbit_morphology1.91898793
26MP0008932_abnormal_embryonic_tissue1.86504668
27MP0003718_maternal_effect1.82855476
28MP0003111_abnormal_nucleus_morphology1.82623511
29MP0005330_cardiomyopathy1.77799652
30MP0004233_abnormal_muscle_weight1.68000466
31MP0003077_abnormal_cell_cycle1.66994137
32MP0002796_impaired_skin_barrier1.66664362
33MP0008058_abnormal_DNA_repair1.61414642
34MP0005058_abnormal_lysosome_morphology1.61065244
35MP0005636_abnormal_mineral_homeostasis1.59599502
36MP0000749_muscle_degeneration1.56973303
37MP0000537_abnormal_urethra_morphology1.55949351
38MP0001666_abnormal_nutrient_absorption1.55514375
39MP0009643_abnormal_urine_homeostasis1.54805255
40MP0005319_abnormal_enzyme/_coenzyme1.54618882
41MP0002132_abnormal_respiratory_system1.54496167
42MP0003656_abnormal_erythrocyte_physiolo1.50758751
43MP0010094_abnormal_chromosome_stability1.47556309
44MP0003123_paternal_imprinting1.46864314
45MP0009672_abnormal_birth_weight1.46361643
46MP0004858_abnormal_nervous_system1.42949990
47MP0001727_abnormal_embryo_implantation1.42538667
48MP0002163_abnormal_gland_morphology1.38180862
49MP0000358_abnormal_cell_content/1.35750121
50MP0001697_abnormal_embryo_size1.35571858
51MP0001672_abnormal_embryogenesis/_devel1.32830127
52MP0005380_embryogenesis_phenotype1.32830127
53MP0005584_abnormal_enzyme/coenzyme_acti1.32629145
54MP0003705_abnormal_hypodermis_morpholog1.25474899
55MP0009333_abnormal_splenocyte_physiolog1.22686385
56MP0003221_abnormal_cardiomyocyte_apopto1.21247431
57MP0001881_abnormal_mammary_gland1.18248619
58MP0004019_abnormal_vitamin_homeostasis1.16595674
59MP0001529_abnormal_vocalization1.16508763
60MP0003984_embryonic_growth_retardation1.16241674
61MP0003315_abnormal_perineum_morphology1.15541212
62MP0003786_premature_aging1.14807805
63MP0005670_abnormal_white_adipose1.13250821
64MP0002249_abnormal_larynx_morphology1.12914806
65MP0003191_abnormal_cellular_cholesterol1.12736666
66MP0002269_muscular_atrophy1.12534040
67MP0008057_abnormal_DNA_replication1.12438274
68MP0000490_abnormal_crypts_of1.11391697
69MP0004147_increased_porphyrin_level1.11340413
70MP0005266_abnormal_metabolism1.10527203
71MP0002085_abnormal_embryonic_tissue1.09771455
72MP0004133_heterotaxia1.09151527
73MP0005666_abnormal_adipose_tissue1.08922194
74MP0001849_ear_inflammation1.08917159
75MP0003011_delayed_dark_adaptation1.08857154
76MP0002088_abnormal_embryonic_growth/wei1.07793486
77MP0005075_abnormal_melanosome_morpholog1.05185387
78MP0004043_abnormal_pH_regulation1.05002022
79MP0010307_abnormal_tumor_latency1.03611544
80MP0010329_abnormal_lipoprotein_level1.03495322
81MP0005220_abnormal_exocrine_pancreas1.03218461
82MP0009053_abnormal_anal_canal1.03021521
83MP0002396_abnormal_hematopoietic_system1.02794118
84MP0004142_abnormal_muscle_tone1.01641812
85MP0005623_abnormal_meninges_morphology1.01253090
86MP0001346_abnormal_lacrimal_gland1.01164618
87MP0005451_abnormal_body_composition1.01080182
88MP0001756_abnormal_urination1.00534435
89MP0008007_abnormal_cellular_replicative0.99976829
90MP0005076_abnormal_cell_differentiation0.99483772
91MP0003252_abnormal_bile_duct0.98924013
92MP0000747_muscle_weakness0.98472533
93MP0005084_abnormal_gallbladder_morpholo0.98412294
94MP0009278_abnormal_bone_marrow0.98256649
95MP0000750_abnormal_muscle_regeneration0.97535121
96MP0000003_abnormal_adipose_tissue0.97052714
97MP0000609_abnormal_liver_physiology0.96496740
98MP0006292_abnormal_olfactory_placode0.96060726
99MP0001853_heart_inflammation0.95852151
100MP0002160_abnormal_reproductive_system0.95839467
101MP0005384_cellular_phenotype0.95444240
102MP0000858_altered_metastatic_potential0.89764591
103MP0008872_abnormal_physiological_respon0.89588307
104MP0001730_embryonic_growth_arrest0.89384548
105MP0000681_abnormal_thyroid_gland0.89366252
106MP0004215_abnormal_myocardial_fiber0.85861089
107MP0005375_adipose_tissue_phenotype0.83810399
108MP0002118_abnormal_lipid_homeostasis0.83677326
109MP0000598_abnormal_liver_morphology0.83242236
110MP0008260_abnormal_autophagy0.82744692
111MP0001905_abnormal_dopamine_level0.82674088
112MP0000751_myopathy0.82650061
113MP0005376_homeostasis/metabolism_phenot0.80870652
114MP0000313_abnormal_cell_death0.80707223
115MP0008469_abnormal_protein_level0.79664910
116MP0010234_abnormal_vibrissa_follicle0.78855784
117MP0002086_abnormal_extraembryonic_tissu0.78815895
118MP0000049_abnormal_middle_ear0.78343062
119MP0004084_abnormal_cardiac_muscle0.78243794
120MP0001661_extended_life_span0.77538555
121MP0002084_abnormal_developmental_patter0.77460356
122MP0001986_abnormal_taste_sensitivity0.76984682
123MP0000703_abnormal_thymus_morphology0.76486345
124MP0005408_hypopigmentation0.76477656
125MP0009697_abnormal_copulation0.76151821
126MP0005621_abnormal_cell_physiology0.74753306
127MP0003763_abnormal_thymus_physiology0.74674173
128MP0005389_reproductive_system_phenotype0.73894224
129MP0005377_hearing/vestibular/ear_phenot0.73285431
130MP0003878_abnormal_ear_physiology0.73285431
131MP0008789_abnormal_olfactory_epithelium0.72890514
132MP0004036_abnormal_muscle_relaxation0.71700733
133MP0005165_increased_susceptibility_to0.71495161
134MP0008873_increased_physiological_sensi0.70594722
135MP0003137_abnormal_impulse_conducting0.70381237
136MP0001873_stomach_inflammation0.69214921
137MP0002111_abnormal_tail_morphology0.69214011
138MP0000627_abnormal_mammary_gland0.69170411
139MP0002080_prenatal_lethality0.69024731
140MP0003941_abnormal_skin_development0.68575960
141MP0002019_abnormal_tumor_incidence0.67808920
142MP0009642_abnormal_blood_homeostasis0.66750978
143MP0008995_early_reproductive_senescence0.66413115
144MP0000759_abnormal_skeletal_muscle0.66141078
145MP0002697_abnormal_eye_size0.65597149
146MP0003567_abnormal_fetal_cardiomyocyte0.65305839
147MP0000477_abnormal_intestine_morphology0.64207366
148MP0002970_abnormal_white_adipose0.63900893
149MP0004808_abnormal_hematopoietic_stem0.63827002
150MP0006276_abnormal_autonomic_nervous0.63627180
151MP0001348_abnormal_lacrimal_gland0.62189248
152MP0002210_abnormal_sex_determination0.61252709
153MP0003942_abnormal_urinary_system0.61189843
154MP0002098_abnormal_vibrissa_morphology0.60990562
155MP0005394_taste/olfaction_phenotype0.60951120
156MP0001919_abnormal_reproductive_system0.60110900
157MP0002751_abnormal_autonomic_nervous0.58959460
158MP0003638_abnormal_response/metabolism_0.57933278
159MP0004145_abnormal_muscle_electrophysio0.57390720
160MP0001663_abnormal_digestive_system0.56822687

Predicted human phenotypes

RankGene SetZ-score
1Hepatocellular necrosis (HP:0001404)5.34553411
2Hepatic necrosis (HP:0002605)5.23428135
3Mitochondrial inheritance (HP:0001427)5.05681405
4Acute necrotizing encephalopathy (HP:0006965)4.94371675
5Decreased activity of mitochondrial respiratory chain (HP:0008972)4.82036202
6Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.82036202
7Abnormal mitochondria in muscle tissue (HP:0008316)4.70855203
8Acute encephalopathy (HP:0006846)4.61078120
9Increased CSF lactate (HP:0002490)4.56316941
10Abnormality of cells of the erythroid lineage (HP:0012130)4.47721449
11Abnormal number of erythroid precursors (HP:0012131)4.31163947
12Lipid accumulation in hepatocytes (HP:0006561)4.13847698
13Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.12242998
14Increased hepatocellular lipid droplets (HP:0006565)4.08768514
15Increased serum lactate (HP:0002151)4.04316393
16Increased intramyocellular lipid droplets (HP:0012240)3.95750287
17Lactic acidosis (HP:0003128)3.90957646
18Progressive macrocephaly (HP:0004481)3.84927743
19Increased muscle lipid content (HP:0009058)3.83456657
20Cerebral edema (HP:0002181)3.81338106
21Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.68129812
22Abnormality of aromatic amino acid family metabolism (HP:0004338)3.62309199
23Macrocytic anemia (HP:0001972)3.61861105
243-Methylglutaconic aciduria (HP:0003535)3.60659786
25Reticulocytopenia (HP:0001896)3.46074359
26Exercise intolerance (HP:0003546)3.34009345
27Renal Fanconi syndrome (HP:0001994)3.33991962
28Respiratory failure (HP:0002878)3.31792111
29Lethargy (HP:0001254)3.12033703
30Abnormality of dicarboxylic acid metabolism (HP:0010995)3.11629551
31Dicarboxylic aciduria (HP:0003215)3.11629551
32CNS demyelination (HP:0007305)3.07706827
33Abnormality of glycolysis (HP:0004366)3.04647812
34Increased serum pyruvate (HP:0003542)3.04647812
35Exertional dyspnea (HP:0002875)3.01324494
36Multiple enchondromatosis (HP:0005701)3.00899737
37Broad distal phalanx of finger (HP:0009836)2.96420809
38Emotional lability (HP:0000712)2.78400991
39Aplasia/Hypoplasia of the sacrum (HP:0008517)2.77282696
40Progressive muscle weakness (HP:0003323)2.76905338
41Hyperammonemia (HP:0001987)2.71961886
42Cerebral hypomyelination (HP:0006808)2.71701645
43Hyperglycinemia (HP:0002154)2.68670274
44Hyperglycinuria (HP:0003108)2.67596725
45Abnormality of fatty-acid metabolism (HP:0004359)2.62814796
46Hyperthyroidism (HP:0000836)2.61151253
47Pallor (HP:0000980)2.60751624
48Oral leukoplakia (HP:0002745)2.54495287
49Abnormality of urine glucose concentration (HP:0011016)2.52549540
50Glycosuria (HP:0003076)2.52549540
51Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.52360649
52Abnormality of alanine metabolism (HP:0010916)2.52360649
53Hyperalaninemia (HP:0003348)2.52360649
54Rhabdomyolysis (HP:0003201)2.51081786
55Ragged-red muscle fibers (HP:0003200)2.50515700
56Respiratory difficulties (HP:0002880)2.50411987
57Selective tooth agenesis (HP:0001592)2.48602536
58Microvesicular hepatic steatosis (HP:0001414)2.48483431
59Abnormality of reticulocytes (HP:0004312)2.46893743
60Hypoglycemic coma (HP:0001325)2.46049401
61Generalized aminoaciduria (HP:0002909)2.45289909
62Breast hypoplasia (HP:0003187)2.44042587
63Nausea (HP:0002018)2.40044368
64Abnormality of glycine metabolism (HP:0010895)2.39225170
65Abnormality of serine family amino acid metabolism (HP:0010894)2.39225170
66Truncus arteriosus (HP:0001660)2.39179065
67Methylmalonic aciduria (HP:0012120)2.38046491
68Birth length less than 3rd percentile (HP:0003561)2.36174909
69Cholecystitis (HP:0001082)2.35134119
70Abnormal gallbladder physiology (HP:0012438)2.35134119
71Abnormality of monocarboxylic acid metabolism (HP:0010996)2.35031741
72Hyperphosphaturia (HP:0003109)2.33866391
73Leukodystrophy (HP:0002415)2.32322649
74Myopathic facies (HP:0002058)2.30938540
75Abnormality of the umbilical cord (HP:0010881)2.30794627
76Microretrognathia (HP:0000308)2.28885112
77Delayed CNS myelination (HP:0002188)2.27620871
78Optic disc pallor (HP:0000543)2.26869345
79Vertebral compression fractures (HP:0002953)2.24239691
80Abnormality of serum amino acid levels (HP:0003112)2.22509895
81Achilles tendon contracture (HP:0001771)2.20625670
82Type I transferrin isoform profile (HP:0003642)2.20500746
83Myoglobinuria (HP:0002913)2.19726502
84Palpitations (HP:0001962)2.18984656
85Ketosis (HP:0001946)2.18347093
86Reduced antithrombin III activity (HP:0001976)2.17015497
87Hypertensive crisis (HP:0100735)2.14909310
88Progressive external ophthalmoplegia (HP:0000590)2.14485603
89Chromosomal breakage induced by crosslinking agents (HP:0003221)2.14431935
90Rough bone trabeculation (HP:0100670)2.12064336
91Vomiting (HP:0002013)2.11883230
92Trismus (HP:0000211)2.09676608
93Abnormality of the tricuspid valve (HP:0001702)2.06652248
94Abnormality of renal resorption (HP:0011038)2.06020764
95Aplastic anemia (HP:0001915)2.05850934
96Hyperacusis (HP:0010780)2.05471312
97Megaloblastic anemia (HP:0001889)2.02805555
98Late onset (HP:0003584)2.02288826
99Hypobetalipoproteinemia (HP:0003563)2.01887463
100Ketoacidosis (HP:0001993)2.01448775
101Metabolic acidosis (HP:0001942)2.00522042
102Seborrheic dermatitis (HP:0001051)2.00034473
103Hypoparathyroidism (HP:0000829)1.95450398
104Squamous cell carcinoma (HP:0002860)1.95292352
105Testicular atrophy (HP:0000029)1.95049764
106Proximal tubulopathy (HP:0000114)1.94624192
107Abnormal hemoglobin (HP:0011902)1.93068737
108Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.92531693
109Abnormal umbilical cord blood vessels (HP:0011403)1.92342304
110Single umbilical artery (HP:0001195)1.92342304
111Abnormality of the fetal cardiovascular system (HP:0010948)1.92342304
112Abnormal trabecular bone morphology (HP:0100671)1.91359778
113Delusions (HP:0000746)1.90995156
114Gliosis (HP:0002171)1.90867709
115Abnormality of pyrimidine metabolism (HP:0004353)1.90807513
116Septate vagina (HP:0001153)1.90546058
117Chromsome breakage (HP:0040012)1.87830807
118Abnormality of the Achilles tendon (HP:0005109)1.87527545
119Carpal bone hypoplasia (HP:0001498)1.87253862
120Ileus (HP:0002595)1.85531811
121Fasciculations (HP:0002380)1.84831114
122Pancytopenia (HP:0001876)1.83844322
123Unsteady gait (HP:0002317)1.82514484
124Secondary amenorrhea (HP:0000869)1.82502437
125Abnormal number of incisors (HP:0011064)1.81148732
126Abnormal protein N-linked glycosylation (HP:0012347)1.80912215
127Abnormal protein glycosylation (HP:0012346)1.80912215
128Abnormal glycosylation (HP:0012345)1.80912215
129Reticulocytosis (HP:0001923)1.79017520
130Hypokinesia (HP:0002375)1.77764201
131Cleft eyelid (HP:0000625)1.77642781
132Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.76235399
133Death in infancy (HP:0001522)1.75939461
134Premature ovarian failure (HP:0008209)1.74754646
135Gout (HP:0001997)1.72959025
136Degeneration of anterior horn cells (HP:0002398)1.72945512
137Abnormality of the anterior horn cell (HP:0006802)1.72945512
138Hypergonadotropic hypogonadism (HP:0000815)1.70067134
139Horseshoe kidney (HP:0000085)1.68467368
140Petechiae (HP:0000967)1.67737484
141Abnormalities of placenta or umbilical cord (HP:0001194)1.67492582
142Centrally nucleated skeletal muscle fibers (HP:0003687)1.66973631
143Opisthotonus (HP:0002179)1.64478923
144Sparse eyelashes (HP:0000653)1.62329198
145Hypoplasia of the capital femoral epiphysis (HP:0003090)1.62253994

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.70935533
2NME24.52281973
3BCKDK4.03061310
4VRK23.77498926
5EIF2AK13.62689685
6STK163.55629426
7TESK23.37053979
8TLK13.15936786
9TRIB33.11561494
10WEE13.04400311
11ARAF2.98010362
12SMG12.96858129
13PIM22.84866505
14NME12.66544294
15MAP3K112.32336046
16IRAK32.03398161
17SRPK12.01088666
18EIF2AK31.97792745
19KDR1.87699287
20BRAF1.83740006
21EEF2K1.70103929
22VRK11.57071727
23MAPKAPK31.40330383
24DYRK31.38004063
25ICK1.30621302
26LMTK21.24660459
27ABL21.24364233
28PLK41.20567303
29AURKA1.17996569
30TESK11.17537127
31CHEK21.11392324
32CDC71.10100737
33RPS6KB21.08875617
34LIMK11.08555381
35MYLK1.06945528
36NEK11.02809804
37TAOK21.02169977
38MAP3K101.01489358
39CDK81.00100270
40DAPK10.95630450
41MAP3K120.94544410
42MAP2K60.90487719
43SIK10.90351062
44TSSK60.90169715
45DAPK30.89999103
46BLK0.89944939
47MUSK0.89655268
48CDK120.88497083
49PRKCI0.87968706
50PLK10.85568403
51CDK40.84922352
52ILK0.84916934
53MAP2K30.84802631
54IRAK40.84463580
55RAF10.84239709
56PDK20.83782819
57ZAK0.82377706
58FLT30.82227222
59RPS6KA40.81963035
60PRPF4B0.81874462
61CHEK10.81780437
62EPHA20.80452965
63MAP2K20.79114828
64SCYL20.77821798
65CDK190.76861730
66CAMK2G0.74720171
67IRAK20.74602266
68STK40.74330051
69ERN10.74033961
70AKT20.73739671
71CDK70.73590369
72PINK10.73419725
73AURKB0.73200737
74CSNK2A20.72015375
75CSNK2A10.71692952
76BRSK20.71474856
77GRK60.71463580
78MST1R0.71249625
79OBSCN0.67107306
80ACVR1B0.66409236
81PBK0.65408202
82MST40.65055373
83PHKG10.64992352
84PHKG20.64992352
85IRAK10.64005593
86MAP3K80.63559074
87PASK0.62479955
88RPS6KA50.62293284
89LRRK20.61478869
90ZAP700.59000753
91TTN0.57150843
92DYRK20.56284068
93PAK10.54939213
94CCNB10.53975107
95TAF10.53008760
96MAPK110.52509848
97CDK11A0.52395042
98TTK0.51836441
99CDK20.49552508
100PAK40.49517840
101MAP4K10.48805062
102PRKD30.47365149
103NEK20.46852625
104PRKG20.46662948
105MTOR0.46624098
106CSNK1G30.46233563
107CDK150.44700321
108CDK90.44465231
109PIK3CG0.44251245
110CDK140.43321980
111BRSK10.42879861
112CDK10.41465735
113MAP3K30.40144926
114MAPK150.39906844
115CDK180.39059535
116PIM10.36343998
117CSNK1A1L0.36235573
118ALK0.33516050
119MAPK40.33400206
120TEC0.32781009
121RPS6KL10.32243079
122RPS6KC10.32243079
123ATM0.30300337
124BMX0.30160088
125NEK90.29675142
126CAMK2D0.29474179
127TBK10.29134844
128PLK30.28896242
129RPS6KA60.27790686
130ATR0.27575096
131BTK0.27228183
132PKN20.26369598
133PNCK0.26052031
134MAPKAPK50.24457194
135CAMK2B0.24386268
136PDK30.24029810
137PDK40.24029810

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.61793189
2Proteasome_Homo sapiens_hsa030503.67954917
3Oxidative phosphorylation_Homo sapiens_hsa001903.58393822
4Parkinsons disease_Homo sapiens_hsa050123.25746503
5RNA polymerase_Homo sapiens_hsa030203.02538251
6DNA replication_Homo sapiens_hsa030302.80533999
7Mismatch repair_Homo sapiens_hsa034302.37054415
8Huntingtons disease_Homo sapiens_hsa050162.30847082
9Protein export_Homo sapiens_hsa030602.29751987
10Pyrimidine metabolism_Homo sapiens_hsa002402.27416197
11Alzheimers disease_Homo sapiens_hsa050102.18075454
12Folate biosynthesis_Homo sapiens_hsa007902.17094106
13Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.07487041
14Sulfur relay system_Homo sapiens_hsa041222.07295124
15Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.98986145
16Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.87586449
17Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.77850830
18Spliceosome_Homo sapiens_hsa030401.73647037
19Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.69231045
202-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.67470273
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.67427328
22Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.61168357
23One carbon pool by folate_Homo sapiens_hsa006701.55458569
24Cyanoamino acid metabolism_Homo sapiens_hsa004601.54423794
25Base excision repair_Homo sapiens_hsa034101.51364344
26Carbon metabolism_Homo sapiens_hsa012001.49354488
27Homologous recombination_Homo sapiens_hsa034401.44625301
28Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.44168130
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.43276685
30Pyruvate metabolism_Homo sapiens_hsa006201.43229906
31Nucleotide excision repair_Homo sapiens_hsa034201.40409162
32Propanoate metabolism_Homo sapiens_hsa006401.36644553
33Drug metabolism - other enzymes_Homo sapiens_hsa009831.36112095
34Biosynthesis of amino acids_Homo sapiens_hsa012301.30027751
35Cardiac muscle contraction_Homo sapiens_hsa042601.29648316
36Glutathione metabolism_Homo sapiens_hsa004801.25634215
37Fatty acid degradation_Homo sapiens_hsa000711.23453033
38Primary bile acid biosynthesis_Homo sapiens_hsa001201.23282220
39Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.22915150
40Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.22358166
41RNA transport_Homo sapiens_hsa030131.18286361
42Purine metabolism_Homo sapiens_hsa002301.16513651
43Pentose phosphate pathway_Homo sapiens_hsa000301.08449837
44Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.08182671
45Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.08122459
46Butanoate metabolism_Homo sapiens_hsa006501.04327069
47Peroxisome_Homo sapiens_hsa041461.02201377
48Pentose and glucuronate interconversions_Homo sapiens_hsa000400.94232978
49Arginine and proline metabolism_Homo sapiens_hsa003300.94112126
50Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.94092066
51Fatty acid elongation_Homo sapiens_hsa000620.93721432
52Metabolic pathways_Homo sapiens_hsa011000.93712198
53Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.93420313
54Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.91170399
55Sulfur metabolism_Homo sapiens_hsa009200.90873096
56beta-Alanine metabolism_Homo sapiens_hsa004100.90636278
57Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.90343589
58mRNA surveillance pathway_Homo sapiens_hsa030150.89341456
59Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.89309373
60Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.88925018
61Fructose and mannose metabolism_Homo sapiens_hsa000510.85630454
62Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.82904906
63Tryptophan metabolism_Homo sapiens_hsa003800.82785477
64Phenylalanine metabolism_Homo sapiens_hsa003600.81495262
65Selenocompound metabolism_Homo sapiens_hsa004500.79955412
66Chemical carcinogenesis_Homo sapiens_hsa052040.78764566
67RNA degradation_Homo sapiens_hsa030180.78222736
68Tyrosine metabolism_Homo sapiens_hsa003500.76925275
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.76738798
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.74174863
71Bladder cancer_Homo sapiens_hsa052190.73936135
72Histidine metabolism_Homo sapiens_hsa003400.71354697
73Galactose metabolism_Homo sapiens_hsa000520.69777125
74Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.67842648
75Arginine biosynthesis_Homo sapiens_hsa002200.65898183
76Fat digestion and absorption_Homo sapiens_hsa049750.64839385
77Maturity onset diabetes of the young_Homo sapiens_hsa049500.61307373
78Alcoholism_Homo sapiens_hsa050340.54701038
79Fatty acid metabolism_Homo sapiens_hsa012120.51846161
80Basal transcription factors_Homo sapiens_hsa030220.51793208
81Vibrio cholerae infection_Homo sapiens_hsa051100.51279467
82Thyroid cancer_Homo sapiens_hsa052160.49533965
83Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.46969296
84Retinol metabolism_Homo sapiens_hsa008300.45644786
85Arachidonic acid metabolism_Homo sapiens_hsa005900.45309361
86Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43519411
87Viral carcinogenesis_Homo sapiens_hsa052030.43477308
88Cell cycle_Homo sapiens_hsa041100.43303835
89Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.42804070
90Caffeine metabolism_Homo sapiens_hsa002320.42054790
91Shigellosis_Homo sapiens_hsa051310.40631321
92Regulation of autophagy_Homo sapiens_hsa041400.40009940
93Fanconi anemia pathway_Homo sapiens_hsa034600.37728585
94Non-homologous end-joining_Homo sapiens_hsa034500.35909239
95Starch and sucrose metabolism_Homo sapiens_hsa005000.35212306
96Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.34792028
97Epstein-Barr virus infection_Homo sapiens_hsa051690.33146788
98Linoleic acid metabolism_Homo sapiens_hsa005910.32769923
99Steroid hormone biosynthesis_Homo sapiens_hsa001400.32218175
100HTLV-I infection_Homo sapiens_hsa051660.32028727
101Non-small cell lung cancer_Homo sapiens_hsa052230.31662762
102Vitamin B6 metabolism_Homo sapiens_hsa007500.30955067
103Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.30744219
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.30240690
105Apoptosis_Homo sapiens_hsa042100.28815652
106Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.28141133
107Chronic myeloid leukemia_Homo sapiens_hsa052200.27813048
108Acute myeloid leukemia_Homo sapiens_hsa052210.27189851
109Other glycan degradation_Homo sapiens_hsa005110.23867589
110Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.23306711
111Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.23183907
112Pancreatic cancer_Homo sapiens_hsa052120.22984008
113N-Glycan biosynthesis_Homo sapiens_hsa005100.22937484
114p53 signaling pathway_Homo sapiens_hsa041150.22366463
115Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.21910418
116Oocyte meiosis_Homo sapiens_hsa041140.21434093
117PPAR signaling pathway_Homo sapiens_hsa033200.20718959
118Steroid biosynthesis_Homo sapiens_hsa001000.20376100
119alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.18963117
120Systemic lupus erythematosus_Homo sapiens_hsa053220.17490471
121Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.16059113
122Primary immunodeficiency_Homo sapiens_hsa053400.16025131
123Herpes simplex infection_Homo sapiens_hsa051680.15037426
124Prion diseases_Homo sapiens_hsa050200.12022301
125Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.09825234

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »