

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.60694309 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.51992180 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.45747348 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.45747348 |
| 5 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.77526162 |
| 6 | proteasome assembly (GO:0043248) | 4.54849359 |
| 7 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.41761177 |
| 8 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.41761177 |
| 9 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.36749037 |
| 10 | respiratory electron transport chain (GO:0022904) | 4.30551839 |
| 11 | electron transport chain (GO:0022900) | 4.28762806 |
| 12 | respiratory chain complex IV assembly (GO:0008535) | 4.20939940 |
| 13 | protein complex biogenesis (GO:0070271) | 4.12164167 |
| 14 | protein neddylation (GO:0045116) | 4.02910994 |
| 15 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.02382698 |
| 16 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.95240620 |
| 17 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.94979819 |
| 18 | cytochrome complex assembly (GO:0017004) | 3.89960193 |
| 19 | rRNA modification (GO:0000154) | 3.87063153 |
| 20 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.84356866 |
| 21 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.77902938 |
| 22 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.65415251 |
| 23 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.54890079 |
| 24 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.48099256 |
| 25 | cullin deneddylation (GO:0010388) | 3.47536006 |
| 26 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.43590378 |
| 27 | chaperone-mediated protein transport (GO:0072321) | 3.40655061 |
| 28 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.37491165 |
| 29 | NADH dehydrogenase complex assembly (GO:0010257) | 3.37491165 |
| 30 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.37491165 |
| 31 | rRNA methylation (GO:0031167) | 3.34594685 |
| 32 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.33386861 |
| 33 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.29251943 |
| 34 | signal peptide processing (GO:0006465) | 3.28134403 |
| 35 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.27913396 |
| 36 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.23198847 |
| 37 | protein deneddylation (GO:0000338) | 3.22848630 |
| 38 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.22492126 |
| 39 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.22492126 |
| 40 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.22492126 |
| 41 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.21409173 |
| 42 | negative regulation of ligase activity (GO:0051352) | 3.20687732 |
| 43 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.20687732 |
| 44 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.18052062 |
| 45 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.18052062 |
| 46 | termination of RNA polymerase III transcription (GO:0006386) | 3.15245948 |
| 47 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.15245948 |
| 48 | hydrogen ion transmembrane transport (GO:1902600) | 3.14879295 |
| 49 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.13959595 |
| 50 | isotype switching (GO:0045190) | 3.13959595 |
| 51 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.13959595 |
| 52 | mannosylation (GO:0097502) | 3.09754869 |
| 53 | proton transport (GO:0015992) | 3.09628429 |
| 54 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.06403672 |
| 55 | hydrogen transport (GO:0006818) | 3.06167409 |
| 56 | C-terminal protein lipidation (GO:0006501) | 3.05064722 |
| 57 | fucose catabolic process (GO:0019317) | 3.03794250 |
| 58 | L-fucose metabolic process (GO:0042354) | 3.03794250 |
| 59 | L-fucose catabolic process (GO:0042355) | 3.03794250 |
| 60 | protein-cofactor linkage (GO:0018065) | 3.03288509 |
| 61 | aldehyde catabolic process (GO:0046185) | 3.03065489 |
| 62 | GPI anchor biosynthetic process (GO:0006506) | 3.02600088 |
| 63 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.02453524 |
| 64 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.02453524 |
| 65 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.01770491 |
| 66 | protein localization to cilium (GO:0061512) | 3.00799098 |
| 67 | GPI anchor metabolic process (GO:0006505) | 3.00009237 |
| 68 | ATP biosynthetic process (GO:0006754) | 2.99801966 |
| 69 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.98734565 |
| 70 | platelet dense granule organization (GO:0060155) | 2.98228968 |
| 71 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.97637306 |
| 72 | lactate metabolic process (GO:0006089) | 2.97589718 |
| 73 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.97312695 |
| 74 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.95739660 |
| 75 | cytidine deamination (GO:0009972) | 2.94337236 |
| 76 | cytidine metabolic process (GO:0046087) | 2.94337236 |
| 77 | cytidine catabolic process (GO:0006216) | 2.94337236 |
| 78 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.94292258 |
| 79 | S-adenosylmethionine metabolic process (GO:0046500) | 2.91899485 |
| 80 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.89316551 |
| 81 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.88953920 |
| 82 | amino acid salvage (GO:0043102) | 2.83774101 |
| 83 | L-methionine salvage (GO:0071267) | 2.83774101 |
| 84 | L-methionine biosynthetic process (GO:0071265) | 2.83774101 |
| 85 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.81345440 |
| 86 | ribosomal large subunit biogenesis (GO:0042273) | 2.77938983 |
| 87 | GTP biosynthetic process (GO:0006183) | 2.76844850 |
| 88 | positive regulation of ligase activity (GO:0051351) | 2.76121335 |
| 89 | organelle disassembly (GO:1903008) | 2.76112532 |
| 90 | C-terminal protein amino acid modification (GO:0018410) | 2.73991400 |
| 91 | tRNA processing (GO:0008033) | 2.72968681 |
| 92 | peptidyl-histidine modification (GO:0018202) | 2.71749707 |
| 93 | maturation of 5.8S rRNA (GO:0000460) | 2.70530328 |
| 94 | cellular ketone body metabolic process (GO:0046950) | 2.69858571 |
| 95 | DNA double-strand break processing (GO:0000729) | 2.69685483 |
| 96 | adenosine metabolic process (GO:0046085) | 2.62556845 |
| 97 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.58710037 |
| 98 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.58710037 |
| 99 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.58280040 |
| 100 | histone mRNA metabolic process (GO:0008334) | 2.56307137 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.44693233 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.94344087 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.43166950 |
| 4 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.90377326 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 2.76998406 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.68898363 |
| 7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.67071691 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.57460164 |
| 9 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.57208718 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.54016747 |
| 11 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.39453350 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.33019374 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.14758875 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.13628472 |
| 15 | EWS_26573619_Chip-Seq_HEK293_Human | 2.12480218 |
| 16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.10530275 |
| 17 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.08651486 |
| 18 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.03603668 |
| 19 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.95527415 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.92157321 |
| 21 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.91823657 |
| 22 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.89411437 |
| 23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.87125063 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.86423323 |
| 25 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.85148028 |
| 26 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.85097670 |
| 27 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.81254027 |
| 28 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.80680305 |
| 29 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.79742675 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.74879211 |
| 31 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.70084983 |
| 32 | P300_19829295_ChIP-Seq_ESCs_Human | 1.67559719 |
| 33 | FUS_26573619_Chip-Seq_HEK293_Human | 1.65877662 |
| 34 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.65158308 |
| 35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.62132945 |
| 36 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.62021004 |
| 37 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.61559821 |
| 38 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.60152121 |
| 39 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.56996661 |
| 40 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.55336152 |
| 41 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.55300148 |
| 42 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.49428713 |
| 43 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.47397631 |
| 44 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.47086564 |
| 45 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.44491865 |
| 46 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.43078266 |
| 47 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.39263642 |
| 48 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.39018134 |
| 49 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.37672929 |
| 50 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.37672929 |
| 51 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.33729158 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.33729158 |
| 53 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.33253313 |
| 54 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.32182249 |
| 55 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.30790844 |
| 56 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.29819183 |
| 57 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.26558700 |
| 58 | GATA3_26560356_Chip-Seq_TH2_Human | 1.25929445 |
| 59 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.25873929 |
| 60 | AR_20517297_ChIP-Seq_VCAP_Human | 1.23368190 |
| 61 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.23152072 |
| 62 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.23039324 |
| 63 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.19800681 |
| 64 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.19691783 |
| 65 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.19225126 |
| 66 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.19225126 |
| 67 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.19187983 |
| 68 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.16842522 |
| 69 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.15143656 |
| 70 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.14567465 |
| 71 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.14271781 |
| 72 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.13996289 |
| 73 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.12795483 |
| 74 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.12090128 |
| 75 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.11863001 |
| 76 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.10349649 |
| 77 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.07412298 |
| 78 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.06092568 |
| 79 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.01957511 |
| 80 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.00598508 |
| 81 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.99989259 |
| 82 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.99963381 |
| 83 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.99673250 |
| 84 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.98901104 |
| 85 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.98699873 |
| 86 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.98523872 |
| 87 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.98444069 |
| 88 | NCOR_22424771_ChIP-Seq_293T_Human | 0.98151827 |
| 89 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.96773680 |
| 90 | AR_25329375_ChIP-Seq_VCAP_Human | 0.92728439 |
| 91 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.92644636 |
| 92 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.91948027 |
| 93 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.91583858 |
| 94 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.91505818 |
| 95 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.91053847 |
| 96 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.91031994 |
| 97 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.90770210 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.90139113 |
| 99 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.89634698 |
| 100 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.89073621 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 3.24393997 |
| 2 | MP0005671_abnormal_response_to | 2.84780254 |
| 3 | MP0002837_dystrophic_cardiac_calcinosis | 2.76663768 |
| 4 | MP0006072_abnormal_retinal_apoptosis | 2.75171589 |
| 5 | MP0002102_abnormal_ear_morphology | 2.69770894 |
| 6 | MP0005084_abnormal_gallbladder_morpholo | 2.45633318 |
| 7 | MP0005075_abnormal_melanosome_morpholog | 2.43989246 |
| 8 | MP0003195_calcinosis | 2.40259722 |
| 9 | MP0005367_renal/urinary_system_phenotyp | 2.32302618 |
| 10 | MP0000516_abnormal_urinary_system | 2.32302618 |
| 11 | MP0008877_abnormal_DNA_methylation | 2.30925121 |
| 12 | MP0003806_abnormal_nucleotide_metabolis | 2.05339768 |
| 13 | MP0006036_abnormal_mitochondrial_physio | 2.05190375 |
| 14 | MP0002163_abnormal_gland_morphology | 2.02956361 |
| 15 | MP0000372_irregular_coat_pigmentation | 2.00205673 |
| 16 | MP0009785_altered_susceptibility_to | 1.98069194 |
| 17 | MP0000685_abnormal_immune_system | 1.94643672 |
| 18 | MP0008872_abnormal_physiological_respon | 1.91593105 |
| 19 | MP0002254_reproductive_system_inflammat | 1.89898020 |
| 20 | MP0002166_altered_tumor_susceptibility | 1.88237304 |
| 21 | MP0005379_endocrine/exocrine_gland_phen | 1.86312361 |
| 22 | MP0001529_abnormal_vocalization | 1.84498909 |
| 23 | MP0000569_abnormal_digit_pigmentation | 1.81266492 |
| 24 | MP0006054_spinal_hemorrhage | 1.67239691 |
| 25 | MP0008058_abnormal_DNA_repair | 1.64160000 |
| 26 | MP0009379_abnormal_foot_pigmentation | 1.62314549 |
| 27 | MP0003786_premature_aging | 1.60691279 |
| 28 | MP0001968_abnormal_touch/_nociception | 1.56757437 |
| 29 | MP0003724_increased_susceptibility_to | 1.55874842 |
| 30 | MP0002876_abnormal_thyroid_physiology | 1.55537414 |
| 31 | MP0009697_abnormal_copulation | 1.55215595 |
| 32 | MP0002006_tumorigenesis | 1.54734742 |
| 33 | MP0002736_abnormal_nociception_after | 1.52502939 |
| 34 | MP0002148_abnormal_hypersensitivity_rea | 1.43788190 |
| 35 | MP0003880_abnormal_central_pattern | 1.42150186 |
| 36 | MP0004142_abnormal_muscle_tone | 1.42104438 |
| 37 | MP0005645_abnormal_hypothalamus_physiol | 1.41475105 |
| 38 | MP0001790_abnormal_immune_system | 1.37231953 |
| 39 | MP0005387_immune_system_phenotype | 1.37231953 |
| 40 | MP0005636_abnormal_mineral_homeostasis | 1.36256253 |
| 41 | MP0005551_abnormal_eye_electrophysiolog | 1.36031094 |
| 42 | MP0009046_muscle_twitch | 1.30123959 |
| 43 | MP0008875_abnormal_xenobiotic_pharmacok | 1.29663564 |
| 44 | MP0001501_abnormal_sleep_pattern | 1.29478725 |
| 45 | MP0002938_white_spotting | 1.28749876 |
| 46 | MP0003252_abnormal_bile_duct | 1.28458749 |
| 47 | MP0003646_muscle_fatigue | 1.26949680 |
| 48 | MP0003787_abnormal_imprinting | 1.26441390 |
| 49 | MP0003186_abnormal_redox_activity | 1.26216912 |
| 50 | MP0005174_abnormal_tail_pigmentation | 1.24886516 |
| 51 | MP0006035_abnormal_mitochondrial_morpho | 1.23027137 |
| 52 | MP0001800_abnormal_humoral_immune | 1.21378980 |
| 53 | MP0005253_abnormal_eye_physiology | 1.20671611 |
| 54 | MP0009333_abnormal_splenocyte_physiolog | 1.19178879 |
| 55 | MP0002751_abnormal_autonomic_nervous | 1.17105000 |
| 56 | MP0005332_abnormal_amino_acid | 1.17017190 |
| 57 | MP0009764_decreased_sensitivity_to | 1.16496776 |
| 58 | MP0004147_increased_porphyrin_level | 1.16189526 |
| 59 | MP0004215_abnormal_myocardial_fiber | 1.13266440 |
| 60 | MP0001905_abnormal_dopamine_level | 1.10632994 |
| 61 | MP0008007_abnormal_cellular_replicative | 1.07503268 |
| 62 | MP0000427_abnormal_hair_cycle | 1.07469341 |
| 63 | MP0008995_early_reproductive_senescence | 1.06775063 |
| 64 | MP0006082_CNS_inflammation | 1.04582715 |
| 65 | MP0005000_abnormal_immune_tolerance | 1.02788290 |
| 66 | MP0001986_abnormal_taste_sensitivity | 1.01992049 |
| 67 | MP0001873_stomach_inflammation | 0.98585539 |
| 68 | MP0002138_abnormal_hepatobiliary_system | 0.98343378 |
| 69 | MP0001765_abnormal_ion_homeostasis | 0.97859715 |
| 70 | MP0002272_abnormal_nervous_system | 0.96576533 |
| 71 | MP0002693_abnormal_pancreas_physiology | 0.95938716 |
| 72 | MP0002723_abnormal_immune_serum | 0.94408208 |
| 73 | MP0001984_abnormal_olfaction | 0.93856014 |
| 74 | MP0003718_maternal_effect | 0.93769616 |
| 75 | MP0001485_abnormal_pinna_reflex | 0.93420034 |
| 76 | MP0002452_abnormal_antigen_presenting | 0.90434057 |
| 77 | MP0004145_abnormal_muscle_electrophysio | 0.89885323 |
| 78 | MP0001756_abnormal_urination | 0.89334494 |
| 79 | MP0004957_abnormal_blastocyst_morpholog | 0.89178770 |
| 80 | MP0009745_abnormal_behavioral_response | 0.85611039 |
| 81 | MP0005410_abnormal_fertilization | 0.85518621 |
| 82 | MP0005408_hypopigmentation | 0.85334547 |
| 83 | MP0003137_abnormal_impulse_conducting | 0.85011110 |
| 84 | MP0003890_abnormal_embryonic-extraembry | 0.84981694 |
| 85 | MP0005085_abnormal_gallbladder_physiolo | 0.84102950 |
| 86 | MP0010094_abnormal_chromosome_stability | 0.83550763 |
| 87 | MP0005319_abnormal_enzyme/_coenzyme | 0.83176103 |
| 88 | MP0001845_abnormal_inflammatory_respons | 0.82164127 |
| 89 | MP0001486_abnormal_startle_reflex | 0.81794018 |
| 90 | MP0006292_abnormal_olfactory_placode | 0.81163185 |
| 91 | MP0003693_abnormal_embryo_hatching | 0.79212770 |
| 92 | MP0001819_abnormal_immune_cell | 0.77038364 |
| 93 | MP0002420_abnormal_adaptive_immunity | 0.76565074 |
| 94 | MP0005389_reproductive_system_phenotype | 0.75142183 |
| 95 | MP0001919_abnormal_reproductive_system | 0.74578620 |
| 96 | MP0001727_abnormal_embryo_implantation | 0.73698713 |
| 97 | MP0005646_abnormal_pituitary_gland | 0.73399883 |
| 98 | MP0002095_abnormal_skin_pigmentation | 0.73102129 |
| 99 | MP0008775_abnormal_heart_ventricle | 0.72871426 |
| 100 | MP0001188_hyperpigmentation | 0.72782576 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.99769805 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.53654411 |
| 3 | Progressive macrocephaly (HP:0004481) | 4.52590686 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.40435660 |
| 5 | Increased CSF lactate (HP:0002490) | 4.24536097 |
| 6 | Hepatocellular necrosis (HP:0001404) | 4.24049306 |
| 7 | Acute encephalopathy (HP:0006846) | 4.18868523 |
| 8 | 3-Methylglutaconic aciduria (HP:0003535) | 3.97653001 |
| 9 | Hepatic necrosis (HP:0002605) | 3.89921327 |
| 10 | Methylmalonic acidemia (HP:0002912) | 3.71176149 |
| 11 | Congenital, generalized hypertrichosis (HP:0004540) | 3.70980204 |
| 12 | Increased hepatocellular lipid droplets (HP:0006565) | 3.70027058 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.56238162 |
| 14 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.49197810 |
| 15 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.49197810 |
| 16 | Cerebral edema (HP:0002181) | 3.16115430 |
| 17 | Exertional dyspnea (HP:0002875) | 3.15580540 |
| 18 | Stomatitis (HP:0010280) | 3.10967825 |
| 19 | Renal Fanconi syndrome (HP:0001994) | 3.00255279 |
| 20 | Methylmalonic aciduria (HP:0012120) | 2.99101187 |
| 21 | Hypoproteinemia (HP:0003075) | 2.86566038 |
| 22 | Pancreatic cysts (HP:0001737) | 2.80219391 |
| 23 | Aplastic anemia (HP:0001915) | 2.75579795 |
| 24 | Hypothermia (HP:0002045) | 2.71200607 |
| 25 | IgG deficiency (HP:0004315) | 2.68434091 |
| 26 | Increased serum lactate (HP:0002151) | 2.66793758 |
| 27 | Abolished electroretinogram (ERG) (HP:0000550) | 2.65144740 |
| 28 | Respiratory failure (HP:0002878) | 2.63178062 |
| 29 | Abnormality of vitamin B metabolism (HP:0004340) | 2.55871089 |
| 30 | Lactic acidosis (HP:0003128) | 2.54577143 |
| 31 | Renal cortical cysts (HP:0000803) | 2.52267976 |
| 32 | Abnormality of the renal cortex (HP:0011035) | 2.51318376 |
| 33 | Leukodystrophy (HP:0002415) | 2.49259399 |
| 34 | Increased intramyocellular lipid droplets (HP:0012240) | 2.40444999 |
| 35 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.39940684 |
| 36 | Abnormality of midbrain morphology (HP:0002418) | 2.37446261 |
| 37 | Molar tooth sign on MRI (HP:0002419) | 2.37446261 |
| 38 | Optic disc pallor (HP:0000543) | 2.36457554 |
| 39 | Abnormality of urine glucose concentration (HP:0011016) | 2.35448074 |
| 40 | Glycosuria (HP:0003076) | 2.35448074 |
| 41 | B lymphocytopenia (HP:0010976) | 2.34246367 |
| 42 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.32211532 |
| 43 | Nephronophthisis (HP:0000090) | 2.27507038 |
| 44 | Thyroiditis (HP:0100646) | 2.24306624 |
| 45 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.21520824 |
| 46 | Abnormality of the prostate (HP:0008775) | 2.20649787 |
| 47 | Congenital stationary night blindness (HP:0007642) | 2.20300622 |
| 48 | Pancreatic fibrosis (HP:0100732) | 2.17970997 |
| 49 | Lethargy (HP:0001254) | 2.15140942 |
| 50 | Abnormality of B cell number (HP:0010975) | 2.14785858 |
| 51 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.14372782 |
| 52 | Type I transferrin isoform profile (HP:0003642) | 2.12969230 |
| 53 | Abnormality of the pons (HP:0007361) | 2.12375575 |
| 54 | Large for gestational age (HP:0001520) | 2.11924097 |
| 55 | CNS demyelination (HP:0007305) | 2.10989417 |
| 56 | Palpitations (HP:0001962) | 2.04875719 |
| 57 | Abnormality of alanine metabolism (HP:0010916) | 2.03396172 |
| 58 | Hyperalaninemia (HP:0003348) | 2.03396172 |
| 59 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.03396172 |
| 60 | Abnormal biliary tract physiology (HP:0012439) | 2.03050343 |
| 61 | Bile duct proliferation (HP:0001408) | 2.03050343 |
| 62 | Medial flaring of the eyebrow (HP:0010747) | 2.01976469 |
| 63 | Polydipsia (HP:0001959) | 2.01824693 |
| 64 | Abnormal drinking behavior (HP:0030082) | 2.01824693 |
| 65 | Generalized aminoaciduria (HP:0002909) | 2.01472245 |
| 66 | Exercise intolerance (HP:0003546) | 2.00538783 |
| 67 | Abnormality of renal resorption (HP:0011038) | 1.99822518 |
| 68 | Severe combined immunodeficiency (HP:0004430) | 1.99612586 |
| 69 | Degeneration of anterior horn cells (HP:0002398) | 1.99296234 |
| 70 | Abnormality of the anterior horn cell (HP:0006802) | 1.99296234 |
| 71 | True hermaphroditism (HP:0010459) | 1.98771080 |
| 72 | Increased muscle lipid content (HP:0009058) | 1.98746548 |
| 73 | Progressive microcephaly (HP:0000253) | 1.95427793 |
| 74 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.94150375 |
| 75 | Abnormality of the renal medulla (HP:0100957) | 1.94019936 |
| 76 | Dicarboxylic aciduria (HP:0003215) | 1.87490622 |
| 77 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.87490622 |
| 78 | Respiratory difficulties (HP:0002880) | 1.86719594 |
| 79 | Pancytopenia (HP:0001876) | 1.85569910 |
| 80 | Hypoplasia of the pons (HP:0012110) | 1.83625482 |
| 81 | Progressive inability to walk (HP:0002505) | 1.82867993 |
| 82 | Cleft eyelid (HP:0000625) | 1.82389381 |
| 83 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.81279697 |
| 84 | Tubular atrophy (HP:0000092) | 1.76979332 |
| 85 | Intestinal atresia (HP:0011100) | 1.76508624 |
| 86 | Abnormality of serum amino acid levels (HP:0003112) | 1.75949249 |
| 87 | Abnormality of the ileum (HP:0001549) | 1.75527942 |
| 88 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.75503789 |
| 89 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.75503789 |
| 90 | Abnormal protein glycosylation (HP:0012346) | 1.75503789 |
| 91 | Abnormal glycosylation (HP:0012345) | 1.75503789 |
| 92 | Hyperglycinemia (HP:0002154) | 1.75373522 |
| 93 | Meckel diverticulum (HP:0002245) | 1.75179865 |
| 94 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.74901378 |
| 95 | Hypoplasia of the fovea (HP:0007750) | 1.74798851 |
| 96 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.74798851 |
| 97 | Azoospermia (HP:0000027) | 1.73154396 |
| 98 | Facial diplegia (HP:0001349) | 1.68603986 |
| 99 | X-linked dominant inheritance (HP:0001423) | 1.68310435 |
| 100 | Abnormality of methionine metabolism (HP:0010901) | 1.68153552 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 3.69298688 |
| 2 | MAP4K2 | 3.28309480 |
| 3 | MAP3K12 | 3.27280404 |
| 4 | FRK | 3.26707791 |
| 5 | NUAK1 | 2.91261267 |
| 6 | TXK | 2.74210312 |
| 7 | EIF2AK3 | 2.72281757 |
| 8 | TLK1 | 2.44682557 |
| 9 | BMPR1B | 2.31582662 |
| 10 | ZAK | 2.26278811 |
| 11 | WNK3 | 2.17261826 |
| 12 | TAOK3 | 2.07616425 |
| 13 | ERBB3 | 1.90094709 |
| 14 | BMPR2 | 1.89815343 |
| 15 | GRK1 | 1.88265107 |
| 16 | PINK1 | 1.84303501 |
| 17 | TRIM28 | 1.72648813 |
| 18 | OXSR1 | 1.72645181 |
| 19 | ADRBK2 | 1.68314586 |
| 20 | STK16 | 1.58507027 |
| 21 | BUB1 | 1.53087037 |
| 22 | VRK2 | 1.49939118 |
| 23 | MYLK | 1.49922182 |
| 24 | PLK4 | 1.43410788 |
| 25 | TNIK | 1.40471898 |
| 26 | NEK1 | 1.36721778 |
| 27 | TSSK6 | 1.35746498 |
| 28 | WNK4 | 1.34461838 |
| 29 | PLK3 | 1.33353985 |
| 30 | EIF2AK1 | 1.31441081 |
| 31 | ACVR1B | 1.30554524 |
| 32 | VRK1 | 1.29389787 |
| 33 | MKNK2 | 1.21422050 |
| 34 | NME1 | 1.19781140 |
| 35 | CDK19 | 1.16374739 |
| 36 | SCYL2 | 1.15536671 |
| 37 | INSRR | 1.10259841 |
| 38 | PHKG2 | 1.08586765 |
| 39 | PHKG1 | 1.08586765 |
| 40 | TRPM7 | 1.06374809 |
| 41 | STK39 | 1.05445020 |
| 42 | MAPK13 | 0.98058557 |
| 43 | IKBKB | 0.97714896 |
| 44 | MAP2K6 | 0.97700499 |
| 45 | TEC | 0.96774099 |
| 46 | DAPK1 | 0.95686423 |
| 47 | EIF2AK2 | 0.93610077 |
| 48 | MKNK1 | 0.92874454 |
| 49 | SRPK1 | 0.91329833 |
| 50 | BCKDK | 0.89209268 |
| 51 | PLK2 | 0.88383566 |
| 52 | CSNK1G3 | 0.88016148 |
| 53 | CSNK1G1 | 0.84575061 |
| 54 | TIE1 | 0.82299846 |
| 55 | MAPKAPK3 | 0.78686250 |
| 56 | MAP4K1 | 0.77780330 |
| 57 | CSNK1G2 | 0.72176352 |
| 58 | STK3 | 0.71650206 |
| 59 | KIT | 0.69356979 |
| 60 | MAP3K14 | 0.62857018 |
| 61 | CSNK1A1L | 0.61378261 |
| 62 | FLT3 | 0.61350288 |
| 63 | DAPK2 | 0.60916347 |
| 64 | PRKCE | 0.58267539 |
| 65 | IKBKE | 0.57706219 |
| 66 | MAP3K4 | 0.56117123 |
| 67 | RPS6KA5 | 0.54402282 |
| 68 | CDC7 | 0.53866825 |
| 69 | ILK | 0.53690160 |
| 70 | TAF1 | 0.51963172 |
| 71 | PAK3 | 0.51886350 |
| 72 | PASK | 0.50993407 |
| 73 | ADRBK1 | 0.48832563 |
| 74 | LYN | 0.47905696 |
| 75 | SYK | 0.46258149 |
| 76 | DYRK2 | 0.45893202 |
| 77 | IGF1R | 0.45524794 |
| 78 | PNCK | 0.44375402 |
| 79 | ITK | 0.43995448 |
| 80 | WEE1 | 0.43349022 |
| 81 | PLK1 | 0.41969478 |
| 82 | ROCK1 | 0.41885068 |
| 83 | TTK | 0.41531457 |
| 84 | GRK7 | 0.41475270 |
| 85 | DAPK3 | 0.38539561 |
| 86 | MAPKAPK5 | 0.36720434 |
| 87 | PRKCQ | 0.34039091 |
| 88 | CSNK1A1 | 0.33960153 |
| 89 | MINK1 | 0.33698068 |
| 90 | ATR | 0.33184592 |
| 91 | CDK3 | 0.32996929 |
| 92 | CSNK2A1 | 0.32969179 |
| 93 | CASK | 0.32694887 |
| 94 | NLK | 0.32673540 |
| 95 | KDR | 0.32076801 |
| 96 | RPS6KA4 | 0.31642105 |
| 97 | LCK | 0.30506775 |
| 98 | CAMK2A | 0.30397449 |
| 99 | PRKACA | 0.29190765 |
| 100 | CSNK2A2 | 0.28802841 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.27691130 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.99206293 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.82378403 |
| 4 | Asthma_Homo sapiens_hsa05310 | 3.59401364 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.06785004 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.53415649 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.47270884 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.39061519 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.33980166 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.25000517 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.21427351 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.06195371 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 1.97731979 |
| 14 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.92481763 |
| 15 | Huntingtons disease_Homo sapiens_hsa05016 | 1.92244647 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.86796651 |
| 17 | Ribosome_Homo sapiens_hsa03010 | 1.68100516 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.60747224 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.60587158 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.55676543 |
| 21 | RNA degradation_Homo sapiens_hsa03018 | 1.51664401 |
| 22 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.49785121 |
| 23 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.45987981 |
| 24 | Mismatch repair_Homo sapiens_hsa03430 | 1.39599717 |
| 25 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.35945531 |
| 26 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.35435259 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.34093561 |
| 28 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.30869241 |
| 29 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.24409845 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.20432168 |
| 31 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.19600666 |
| 32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.17308141 |
| 33 | Basal transcription factors_Homo sapiens_hsa03022 | 1.15371713 |
| 34 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.14772179 |
| 35 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.11913010 |
| 36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.10519343 |
| 37 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.07675753 |
| 38 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.01046107 |
| 39 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.95822958 |
| 40 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.94530431 |
| 41 | Viral myocarditis_Homo sapiens_hsa05416 | 0.92776156 |
| 42 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.92437189 |
| 43 | RNA transport_Homo sapiens_hsa03013 | 0.91290143 |
| 44 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.90651012 |
| 45 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.87778375 |
| 46 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.84368200 |
| 47 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.82691541 |
| 48 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.80179330 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 0.79368820 |
| 50 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.76823168 |
| 51 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.76079287 |
| 52 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.75892308 |
| 53 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.74914878 |
| 54 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.73741392 |
| 55 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.73677604 |
| 56 | Peroxisome_Homo sapiens_hsa04146 | 0.73375344 |
| 57 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.71503641 |
| 58 | DNA replication_Homo sapiens_hsa03030 | 0.70712267 |
| 59 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.69862156 |
| 60 | Spliceosome_Homo sapiens_hsa03040 | 0.67912047 |
| 61 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.66684730 |
| 62 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.64428920 |
| 63 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.60740403 |
| 64 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.60694328 |
| 65 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.60376520 |
| 66 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.59773083 |
| 67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58862627 |
| 68 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.56344215 |
| 69 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.50874080 |
| 70 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.50826232 |
| 71 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.50592127 |
| 72 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.49103629 |
| 73 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.48082575 |
| 74 | Leishmaniasis_Homo sapiens_hsa05140 | 0.47080456 |
| 75 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.46850508 |
| 76 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.46530496 |
| 77 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.45688113 |
| 78 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.45531505 |
| 79 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.45396441 |
| 80 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.44486080 |
| 81 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.43159951 |
| 82 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.42936385 |
| 83 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.42605895 |
| 84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.37762259 |
| 85 | Retinol metabolism_Homo sapiens_hsa00830 | 0.36793997 |
| 86 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.36664224 |
| 87 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.34442617 |
| 88 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.34340703 |
| 89 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.32776618 |
| 90 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.32246209 |
| 91 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.31831601 |
| 92 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.31273015 |
| 93 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.26335563 |
| 94 | Olfactory transduction_Homo sapiens_hsa04740 | 0.25746656 |
| 95 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.25627285 |
| 96 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.25230055 |
| 97 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.24962779 |
| 98 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.24455578 |
| 99 | GABAergic synapse_Homo sapiens_hsa04727 | 0.23105693 |
| 100 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.22201401 |

