MS4A14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sperm-egg recognition (GO:0035036)9.77674549
2acrosome assembly (GO:0001675)9.73177494
3plasma membrane fusion (GO:0045026)9.54837174
4cell wall macromolecule catabolic process (GO:0016998)9.50263870
5cell wall macromolecule metabolic process (GO:0044036)9.50263870
6cell-cell recognition (GO:0009988)8.90227686
7axonemal dynein complex assembly (GO:0070286)8.86433751
8epithelial cilium movement (GO:0003351)8.83517438
9reproduction (GO:0000003)8.71896841
10binding of sperm to zona pellucida (GO:0007339)8.67363214
11spermatid development (GO:0007286)8.11242952
12motile cilium assembly (GO:0044458)7.69415650
13regulation of cilium movement (GO:0003352)7.68022390
14protein targeting to Golgi (GO:0000042)7.57230567
15cilium movement (GO:0003341)7.29223565
16establishment of protein localization to Golgi (GO:0072600)7.24958988
17retrograde transport, vesicle recycling within Golgi (GO:0000301)7.14803793
18single fertilization (GO:0007338)6.97194739
19epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.67360679
20phosphatidylethanolamine biosynthetic process (GO:0006646)6.49853173
21male meiosis (GO:0007140)6.48651764
22sperm capacitation (GO:0048240)6.47293916
23piRNA metabolic process (GO:0034587)6.29416075
24single strand break repair (GO:0000012)6.25814761
25rRNA methylation (GO:0031167)6.09468196
26phosphatidylethanolamine metabolic process (GO:0046337)6.02794627
27synaptonemal complex organization (GO:0070193)5.91994019
28fertilization (GO:0009566)5.77036494
29synaptonemal complex assembly (GO:0007130)5.70539257
30spermatogenesis (GO:0007283)5.31485735
31microtubule depolymerization (GO:0007019)5.30019977
32male gamete generation (GO:0048232)5.29427787
33protein localization to Golgi apparatus (GO:0034067)5.21726812
34negative regulation of inclusion body assembly (GO:0090084)5.08052449
35organic cation transport (GO:0015695)5.05954121
36ventricular system development (GO:0021591)5.02677229
37centriole replication (GO:0007099)4.98745777
38rRNA modification (GO:0000154)4.93793089
39gamete generation (GO:0007276)4.86452993
40cellular process involved in reproduction in multicellular organism (GO:0022412)4.60486806
41centriole assembly (GO:0098534)4.51711735
42germ cell development (GO:0007281)4.51003501
43regulation of microtubule-based movement (GO:0060632)4.47739217
44male meiosis I (GO:0007141)4.44372358
45regulation of T-helper 2 cell differentiation (GO:0045628)4.35968477
46calcium ion-dependent exocytosis (GO:0017156)4.27194375
47regulation of inclusion body assembly (GO:0090083)4.21386469
48regulation of Rab GTPase activity (GO:0032313)4.09270759
49positive regulation of Rab GTPase activity (GO:0032851)4.09270759
50cell recognition (GO:0008037)4.04856003
51modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.99159849
52positive regulation by organism of defense response of other organism involved in symbiotic interact3.99159849
53modulation by symbiont of host immune response (GO:0052553)3.99159849
54positive regulation by symbiont of host defense response (GO:0052509)3.99159849
55modulation by symbiont of host defense response (GO:0052031)3.99159849
56modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.99159849
57response to pheromone (GO:0019236)3.96314555
58chromosome organization involved in meiosis (GO:0070192)3.94398092
59multicellular organismal reproductive process (GO:0048609)3.83599989
60natural killer cell mediated immunity (GO:0002228)3.83163057
61natural killer cell mediated cytotoxicity (GO:0042267)3.83163057
62monoubiquitinated protein deubiquitination (GO:0035520)3.82356150
63membrane protein intracellular domain proteolysis (GO:0031293)3.73409422
64DNA methylation involved in gamete generation (GO:0043046)3.71417396
65positive regulation of type 2 immune response (GO:0002830)3.67715037
66left/right pattern formation (GO:0060972)3.66972419
67nucleus organization (GO:0006997)3.66722921
68glycerol ether metabolic process (GO:0006662)3.62009900
69microtubule severing (GO:0051013)3.55214646
70meiotic nuclear division (GO:0007126)3.55098936
71seminiferous tubule development (GO:0072520)3.54576939
72microtubule nucleation (GO:0007020)3.54499353
73meiosis I (GO:0007127)3.51383546
74glomerular visceral epithelial cell development (GO:0072015)3.50670857
75multicellular organismal movement (GO:0050879)3.50555908
76musculoskeletal movement (GO:0050881)3.50555908
77ether metabolic process (GO:0018904)3.31513539
78regulation of interferon-beta biosynthetic process (GO:0045357)3.29039241
79glomerular epithelial cell development (GO:0072310)3.28206052
80cellular ketone body metabolic process (GO:0046950)3.21749872
81genitalia morphogenesis (GO:0035112)3.20680577
82regulation of transcription involved in cell fate commitment (GO:0060850)3.17544863
83microglial cell activation (GO:0001774)3.14100313
84peptide catabolic process (GO:0043171)3.13185601
85polyamine biosynthetic process (GO:0006596)3.12168265
86chromatin silencing (GO:0006342)3.09853230
87response to acidic pH (GO:0010447)3.06688359
88positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.06259440
89homeostasis of number of cells within a tissue (GO:0048873)3.06174242
90regulation of podosome assembly (GO:0071801)3.04128000
91macroautophagy (GO:0016236)2.99914050
92regulation of protein polyubiquitination (GO:1902914)2.99793398
93multicellular organismal development (GO:0007275)2.98121957
94myeloid cell activation involved in immune response (GO:0002275)2.96320170
95histone H3-K9 demethylation (GO:0033169)2.95024310
96chromosome condensation (GO:0030261)2.93919878
97regulation of ARF GTPase activity (GO:0032312)2.91456484
98regulation of interleukin-13 production (GO:0032656)2.91127421
99protein localization to cilium (GO:0061512)2.90477508
100spermatid nucleus differentiation (GO:0007289)2.87218486
101DNA packaging (GO:0006323)2.86338998
102intra-Golgi vesicle-mediated transport (GO:0006891)2.85945377
103cellular response to pH (GO:0071467)2.83111974
104ketone body metabolic process (GO:1902224)2.79166324
105chaperone-mediated protein complex assembly (GO:0051131)2.77864120
106meiotic cell cycle (GO:0051321)2.75700795
107positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.74784393
108positive regulation of gamma-delta T cell activation (GO:0046645)2.72908049
109lactate metabolic process (GO:0006089)2.72832340
110positive regulation of mast cell activation (GO:0033005)2.67941649
111antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.67568880
112negative regulation of Rho protein signal transduction (GO:0035024)2.67400357
113protein K11-linked deubiquitination (GO:0035871)2.65505221
114positive regulation of mast cell degranulation (GO:0043306)2.63894158
115positive regulation of mast cell activation involved in immune response (GO:0033008)2.63894158
116nuclear pore complex assembly (GO:0051292)2.63859412
117regulation of gamma-delta T cell activation (GO:0046643)2.63270179
118macrophage activation involved in immune response (GO:0002281)2.62572158
119microtubule-based movement (GO:0007018)2.60507857
120positive regulation of interferon-alpha production (GO:0032727)2.60342458
121protein polyglutamylation (GO:0018095)2.59212905
122negative regulation of organelle assembly (GO:1902116)2.59184446
123glycolytic process (GO:0006096)2.58456744
124leukocyte mediated cytotoxicity (GO:0001909)2.55523838
125microtubule polymerization or depolymerization (GO:0031109)2.53365030
126response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.53194486
127response to host immune response (GO:0052572)2.53194486
128regulation of spindle checkpoint (GO:0090231)2.52943874
129neutrophil activation involved in immune response (GO:0002283)2.52694073
130response to peptidoglycan (GO:0032494)2.50904915
131synapsis (GO:0007129)2.48789461
132nucleoside diphosphate phosphorylation (GO:0006165)2.47708732
133RNA destabilization (GO:0050779)2.46621054
134regulation of interferon-alpha production (GO:0032647)2.46453426
135sexual reproduction (GO:0019953)2.45264366
136polyol catabolic process (GO:0046174)2.37007633
137cilium organization (GO:0044782)2.35347278
138regulation of centriole replication (GO:0046599)2.35190128
139NLS-bearing protein import into nucleus (GO:0006607)2.34637961
140fusion of sperm to egg plasma membrane (GO:0007342)12.6953113
141sperm motility (GO:0030317)12.1568358
142cilium or flagellum-dependent cell motility (GO:0001539)10.5509454
143multicellular organism reproduction (GO:0032504)10.5093469
144acrosome reaction (GO:0007340)10.0359706

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse7.70549598
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.98243462
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.95786233
4IRF8_21731497_ChIP-ChIP_J774_Mouse3.55374385
5MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.92553483
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.86567886
7IRF8_27001747_Chip-Seq_BMDM_Mouse2.75553265
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.74009921
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.66746863
10Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.66449495
11EZH2_22144423_ChIP-Seq_EOC_Human2.35572259
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.33904489
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.33843750
14VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.29829413
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.25478035
16PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.22855150
17RUNX_20019798_ChIP-Seq_JUKART_Human2.07970049
18PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.90853054
19EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.89195003
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.88369000
21DROSHA_22980978_ChIP-Seq_HELA_Human1.86573040
22STAT6_21828071_ChIP-Seq_BEAS2B_Human1.86049471
23PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.83178337
24SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.82021259
25BP1_19119308_ChIP-ChIP_Hs578T_Human1.81856959
26ELF1_20517297_ChIP-Seq_JURKAT_Human1.81681703
27CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.74892724
28FLI1_27457419_Chip-Seq_LIVER_Mouse1.71769477
29ELK4_26923725_Chip-Seq_MESODERM_Mouse1.71388211
30BCL6_27268052_Chip-Seq_Bcells_Human1.68092126
31NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.68011481
32VDR_24787735_ChIP-Seq_THP-1_Human1.61978359
33VDR_22108803_ChIP-Seq_LS180_Human1.60564779
34BCOR_27268052_Chip-Seq_Bcells_Human1.58884086
35SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.57973259
36TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.57113989
37* RAC3_21632823_ChIP-Seq_H3396_Human1.56934036
38CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.56725158
39PCGF2_27294783_Chip-Seq_ESCs_Mouse1.53672004
40ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.53197532
41LXR_22292898_ChIP-Seq_THP-1_Human1.51800951
42STAT1_17558387_ChIP-Seq_HELA_Human1.50312414
43EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.50169496
44RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.46240172
45NANOG_20526341_ChIP-Seq_ESCs_Human1.44914079
46PCGF2_27294783_Chip-Seq_NPCs_Mouse1.43433159
47IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.42612645
48FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41799941
49SMC4_20622854_ChIP-Seq_HELA_Human1.41719717
50CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41149022
51GATA1_26923725_Chip-Seq_HPCs_Mouse1.40816352
52TAF2_19829295_ChIP-Seq_ESCs_Human1.40676866
53YY1_22570637_ChIP-Seq_MALME-3M_Human1.38921630
54GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.38575910
55GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.35686360
56SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.34087528
57STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.33672583
58MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.30826908
59P68_20966046_ChIP-Seq_HELA_Human1.28968868
60* ERA_21632823_ChIP-Seq_H3396_Human1.28537835
61PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.28117593
62TP63_22573176_ChIP-Seq_HFKS_Human1.27597576
63PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.27370643
64OCT4_20526341_ChIP-Seq_ESCs_Human1.27117757
65P300_27268052_Chip-Seq_Bcells_Human1.26800629
66KDM2B_26808549_Chip-Seq_REH_Human1.26712804
67ARNT_22903824_ChIP-Seq_MCF-7_Human1.26065602
68CTCF_27219007_Chip-Seq_Bcells_Human1.26060591
69MYC_19829295_ChIP-Seq_ESCs_Human1.25497614
70MYB_21317192_ChIP-Seq_ERMYB_Mouse1.25374729
71SMRT_27268052_Chip-Seq_Bcells_Human1.25343042
72GATA1_19941826_ChIP-Seq_K562_Human1.24817344
73CTBP2_25329375_ChIP-Seq_LNCAP_Human1.24205431
74NFE2_27457419_Chip-Seq_LIVER_Mouse1.23606055
75PHF8_20622854_ChIP-Seq_HELA_Human1.23592240
76CEBPB_22108803_ChIP-Seq_LS180_Human1.23286316
77CBP_20019798_ChIP-Seq_JUKART_Human1.21828477
78IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.21828477
79TDRD3_21172665_ChIP-Seq_MCF-7_Human1.21344338
80CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.21262033
81MYB_26560356_Chip-Seq_TH2_Human1.21098875
82E2F1_20622854_ChIP-Seq_HELA_Human1.20823463
83RBPJ_21746931_ChIP-Seq_IB4_Human1.20587666
84ERG_20517297_ChIP-Seq_VCAP_Human1.20491695
85P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.19090055
86TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.18844189
87KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.18255384
88HNFA_21074721_ChIP-Seq_CACO-2_Human1.17954990
89CBX2_22325352_ChIP-Seq_293T-Rex_Human1.17855032
90KAP1_22055183_ChIP-Seq_ESCs_Mouse1.17473475
91SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.17335214
92BRD4_27068464_Chip-Seq_AML-cells_Mouse1.17069760
93UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16830154
94VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.16737490
95ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.16650343
96ER_23166858_ChIP-Seq_MCF-7_Human1.16491458
97SMAD4_21741376_ChIP-Seq_EPCs_Human1.16358918
98CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.16188204
99GATA3_21867929_ChIP-Seq_TH1_Mouse1.15853157
100CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15593838
101TAL1_26923725_Chip-Seq_HPCs_Mouse1.15194954
102CTCF_20526341_ChIP-Seq_ESCs_Human1.14768116
103MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.14569942
104SUZ12_27294783_Chip-Seq_NPCs_Mouse1.13909169
105ETV2_25802403_ChIP-Seq_MESCs_Mouse1.12838316
106FUS_26573619_Chip-Seq_HEK293_Human1.11899160
107ETV1_20927104_ChIP-Seq_GIST48_Human1.11421103
108SPI1_20517297_ChIP-Seq_HL60_Human1.10613720
109SOX2_22085726_ChIP-Seq_NPCs_Mouse1.10142807
110PU_27001747_Chip-Seq_BMDM_Mouse1.09891200
111PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.09789810
112MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.09509574
113LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.09492567
114RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.09259692
115PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.08538288
116STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.07992938
117WDR5_24793694_ChIP-Seq_LNCAP_Human1.07637411
118IKZF1_21737484_ChIP-ChIP_HCT116_Human1.07589181
119FLI1_21867929_ChIP-Seq_TH2_Mouse1.07583159
120CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.07559071
121SCL_19346495_ChIP-Seq_HPC-7_Human1.06229014
122POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.06020154
123TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06020154
124NANOG_18555785_Chip-Seq_ESCs_Mouse1.05690906
125CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05622759
126AUTS2_25519132_ChIP-Seq_293T-REX_Human1.05518846
127CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.04687494
128ZNF274_21170338_ChIP-Seq_K562_Hela1.04511154
129CRX_20693478_ChIP-Seq_RETINA_Mouse1.04395001
130SA1_27219007_Chip-Seq_Bcells_Human1.04287763
131E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.04242317
132GATA3_21867929_ChIP-Seq_CD8_Mouse1.03580475
133RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.03434159
134MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.03387667
135PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.02888086
136GF1_26923725_Chip-Seq_HPCs_Mouse1.02082388
137CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01616054
138GATA3_27048872_Chip-Seq_THYMUS_Human1.01418999
139VDR_24763502_ChIP-Seq_THP-1_Human1.01301813
140TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human1.01057884
141AR_25329375_ChIP-Seq_VCAP_Human1.00948731
142P53_22387025_ChIP-Seq_ESCs_Mouse1.00705927
143GATA6_21074721_ChIP-Seq_CACO-2_Human1.00027526
144THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.99407991
145KLF4_19829295_ChIP-Seq_ESCs_Human0.98905359
146SPI1_23127762_ChIP-Seq_K562_Human0.98748483
147OCT4_18555785_Chip-Seq_ESCs_Mouse0.98648434
148OCT4_21477851_ChIP-Seq_ESCs_Mouse0.98354239
149SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97720692
150RUNX1_26923725_Chip-Seq_HPCs_Mouse0.97636158
151PU1_27457419_Chip-Seq_LIVER_Mouse0.97524749
152NFYB_21822215_ChIP-Seq_K562_Human0.97189388
153OCT4_19829295_ChIP-Seq_ESCs_Human0.96490422
154LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.96334369
155SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.96180587
156GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.95936313
157CMYC_18555785_Chip-Seq_ESCs_Mouse0.95609617
158EZH2_27294783_Chip-Seq_NPCs_Mouse0.95116581
159PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.94384777
160SMAD3_21741376_ChIP-Seq_ESCs_Human0.94351386
161GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93968799
162SA1_27219007_Chip-Seq_ERYTHROID_Human0.93818899
163CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93705302
164NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.93553583
165GATA1_19941827_ChIP-Seq_MEL86_Mouse0.92219810
166P300_18555785_Chip-Seq_ESCs_Mouse0.92218945
167NFIB_24661679_ChIP-Seq_LUNG_Mouse0.92107938
168EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.91943704
169EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.91872449
170KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.91398685
171FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91343680
172EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.91253756
173ZFP57_27257070_Chip-Seq_ESCs_Mouse0.91227151
174ESRRB_18555785_Chip-Seq_ESCs_Mouse0.90621310
175P53_21459846_ChIP-Seq_SAOS-2_Human0.90296804
176STAT3_18555785_Chip-Seq_ESCs_Mouse0.89706466

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot4.91115877
2MP0003878_abnormal_ear_physiology4.91115877
3MP0000569_abnormal_digit_pigmentation4.79105743
4MP0003698_abnormal_male_reproductive4.60319167
5MP0001929_abnormal_gametogenesis4.03888300
6MP0008877_abnormal_DNA_methylation3.17861190
7MP0005451_abnormal_body_composition2.69769200
8MP0005058_abnormal_lysosome_morphology2.48163699
9MP0002210_abnormal_sex_determination2.47854527
10MP0002161_abnormal_fertility/fecundity2.45676838
11MP0001835_abnormal_antigen_presentation2.44161058
12MP0009278_abnormal_bone_marrow2.39784664
13MP0001348_abnormal_lacrimal_gland2.38760347
14MP0006082_CNS_inflammation2.21653127
15MP0005670_abnormal_white_adipose2.20522560
16MP0001145_abnormal_male_reproductive2.05255771
17MP0005410_abnormal_fertilization12.6510689
18MP0002132_abnormal_respiratory_system1.95373755
19MP0003172_abnormal_lysosome_physiology1.88863303
20MP0003436_decreased_susceptibility_to1.85936342
21MP0002653_abnormal_ependyma_morphology1.84815031
22MP0002419_abnormal_innate_immunity1.79192766
23MP0000653_abnormal_sex_gland1.66117646
24MP0005174_abnormal_tail_pigmentation1.65317869
25MP0003303_peritoneal_inflammation1.58771460
26MP0002148_abnormal_hypersensitivity_rea1.54481056
27MP0005623_abnormal_meninges_morphology1.54332797
28MP0005000_abnormal_immune_tolerance1.54275535
29MP0005397_hematopoietic_system_phenotyp1.52189980
30MP0001545_abnormal_hematopoietic_system1.52189980
31MP0009785_altered_susceptibility_to1.49084394
32MP0005025_abnormal_response_to1.48331443
33MP0003879_abnormal_hair_cell1.48046790
34MP0003183_abnormal_peptide_metabolism1.45663156
35MP0002723_abnormal_immune_serum1.33998098
36MP0002452_abnormal_antigen_presenting1.32906506
37MP0000015_abnormal_ear_pigmentation1.31594128
38MP0001485_abnormal_pinna_reflex1.30571832
39MP0001790_abnormal_immune_system1.29977248
40MP0005387_immune_system_phenotype1.29977248
41MP0000604_amyloidosis1.29602496
42MP0000685_abnormal_immune_system1.28794137
43MP0000678_abnormal_parathyroid_gland1.27648626
44MP0001800_abnormal_humoral_immune1.26662153
45MP0003828_pulmonary_edema1.22037593
46MP0002405_respiratory_system_inflammati1.21599706
47MP0005464_abnormal_platelet_physiology1.20030547
48MP0003011_delayed_dark_adaptation1.19890441
49MP0002138_abnormal_hepatobiliary_system1.19486119
50MP0010307_abnormal_tumor_latency1.18290373
51MP0004510_myositis1.14986686
52MP0003690_abnormal_glial_cell1.14507022
53MP0005167_abnormal_blood-brain_barrier1.13556643
54MP0005379_endocrine/exocrine_gland_phen1.06288493
55MP0005666_abnormal_adipose_tissue1.05929304
56MP0003300_gastrointestinal_ulcer1.05226536
57MP0003718_maternal_effect1.04945500
58MP0004947_skin_inflammation1.04847139
59MP0001819_abnormal_immune_cell1.03487300
60MP0002420_abnormal_adaptive_immunity1.01997752
61MP0003448_altered_tumor_morphology1.01923903
62MP0004742_abnormal_vestibular_system1.01691171
63MP0008469_abnormal_protein_level0.98039965
64MP0002282_abnormal_trachea_morphology0.97204948
65MP0003646_muscle_fatigue0.96017672
66MP0003724_increased_susceptibility_to0.95827486
67MP0001486_abnormal_startle_reflex0.94981826
68MP0001533_abnormal_skeleton_physiology0.91161824
69MP0001845_abnormal_inflammatory_respons0.86967533
70MP0001765_abnormal_ion_homeostasis0.85547621
71MP0005083_abnormal_biliary_tract0.85313912
72MP0003950_abnormal_plasma_membrane0.81075994
73MP0009046_muscle_twitch0.78820972
74MP0004883_abnormal_blood_vessel0.78230775
75MP0002928_abnormal_bile_duct0.77395554
76MP0005164_abnormal_response_to0.77059866
77MP0005647_abnormal_sex_gland0.75447998
78MP0001963_abnormal_hearing_physiology0.74166222
79MP0000689_abnormal_spleen_morphology0.72861447
80MP0001853_heart_inflammation0.72612447
81MP0009840_abnormal_foam_cell0.72470954
82MP0005671_abnormal_response_to0.72235759
83MP0002398_abnormal_bone_marrow0.71133436
84MP0000343_altered_response_to0.70938630
85MP0002006_tumorigenesis0.70528773
86MP0009764_decreased_sensitivity_to0.70100020
87MP0005423_abnormal_somatic_nervous0.69816643
88MP0000716_abnormal_immune_system0.68676513
89MP0002229_neurodegeneration0.66712467
90MP0005375_adipose_tissue_phenotype0.65115332
91MP0005248_abnormal_Harderian_gland0.64879678
92MP0002166_altered_tumor_susceptibility0.64812688
93MP0000371_diluted_coat_color0.63848123
94MP0004808_abnormal_hematopoietic_stem0.63821119
95MP0008004_abnormal_stomach_pH0.63496278
96MP0003045_fibrosis0.63381735
97MP0002998_abnormal_bone_remodeling0.62725217
98MP0005535_abnormal_body_temperature0.62574507
99MP0002127_abnormal_cardiovascular_syste0.61958565
100MP0003329_amyloid_beta_deposits0.61822177
101MP0001851_eye_inflammation0.61772591
102MP0005076_abnormal_cell_differentiation0.61520283
103MP0000858_altered_metastatic_potential0.60646447
104MP0001324_abnormal_eye_pigmentation0.59994040
105MP0001958_emphysema0.59941341
106MP0004484_altered_response_of0.59831236
107MP0003191_abnormal_cellular_cholesterol0.57375454
108MP0002277_abnormal_respiratory_mucosa0.57361335
109MP0009763_increased_sensitivity_to0.56392825
110MP0001873_stomach_inflammation0.56314108
111MP0005395_other_phenotype0.56010150
112MP0008874_decreased_physiological_sensi0.55497298
113MP0002160_abnormal_reproductive_system0.53733749
114MP0008569_lethality_at_weaning0.53280337
115MP0002429_abnormal_blood_cell0.52107557
116MP0000249_abnormal_blood_vessel0.51883660
117MP0009765_abnormal_xenobiotic_induced0.51533716
118MP0003075_altered_response_to0.50087959
119MP0000703_abnormal_thymus_morphology0.49228155
120MP0008058_abnormal_DNA_repair0.49200842
121MP0009115_abnormal_fat_cell0.48796415
122MP0008260_abnormal_autophagy0.48291613
123MP0010329_abnormal_lipoprotein_level0.47964326
124MP0000920_abnormal_myelination0.47743472
125MP0005310_abnormal_salivary_gland0.46206751
126MP0003091_abnormal_cell_migration0.45467534
127MP0002722_abnormal_immune_system0.45399677
128MP0003633_abnormal_nervous_system0.43169218
129MP0010155_abnormal_intestine_physiology0.42605708
130MP0008995_early_reproductive_senescence0.42481409
131MP0002295_abnormal_pulmonary_circulatio0.42285504
132MP0000358_abnormal_cell_content/0.42132107
133MP0005166_decreased_susceptibility_to0.39951085
134MP0004233_abnormal_muscle_weight0.38568180
135MP0003634_abnormal_glial_cell0.37743684
136MP0002254_reproductive_system_inflammat0.36280474

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)7.94809856
2Abnormal respiratory epithelium morphology (HP:0012253)7.84440429
3Abnormal respiratory motile cilium morphology (HP:0005938)7.84440429
4Abnormal ciliary motility (HP:0012262)6.50569332
5Rhinitis (HP:0012384)6.41204627
6Severe visual impairment (HP:0001141)6.36985466
7Nasal polyposis (HP:0100582)5.99241855
8Infertility (HP:0000789)5.74689966
9Chronic bronchitis (HP:0004469)5.73123145
10Chronic hepatic failure (HP:0100626)5.33458764
11Parkinsonism with favorable response to dopaminergic medication (HP:0002548)5.26584144
12Abnormality of the nasal mucosa (HP:0000433)4.93449351
13Cone-rod dystrophy (HP:0000548)4.52024262
14Male infertility (HP:0003251)4.34026163
15Resting tremor (HP:0002322)4.33991149
16Bronchitis (HP:0012387)4.26490815
17Hyperkalemia (HP:0002153)4.25481133
18Hypoplasia of the thymus (HP:0000778)4.01444296
19Bronchiectasis (HP:0002110)3.97900748
20Menstrual irregularities (HP:0000858)3.96117666
21Hypoalphalipoproteinemia (HP:0003233)3.81065308
22Progressive sensorineural hearing impairment (HP:0000408)3.71386583
23Nephronophthisis (HP:0000090)3.66267046
24Postural instability (HP:0002172)3.51103528
25Abnormality of macular pigmentation (HP:0008002)3.50090626
26Attenuation of retinal blood vessels (HP:0007843)3.44520645
27Recurrent sinusitis (HP:0011108)3.42421333
28Bony spicule pigmentary retinopathy (HP:0007737)3.42244365
29Abnormal spermatogenesis (HP:0008669)3.38099239
30Recurrent bronchitis (HP:0002837)3.28735929
31Gastrointestinal infarctions (HP:0005244)3.25267359
32Amelogenesis imperfecta (HP:0000705)3.24594424
33Truncal obesity (HP:0001956)3.18223996
34Portal hypertension (HP:0001409)3.14436779
35Recurrent abscess formation (HP:0002722)3.07269538
36Recurrent bacterial skin infections (HP:0005406)3.03973935
37Recurrent otitis media (HP:0000403)3.01002851
38Abnormality of dental color (HP:0011073)2.99562541
39Aplasia/Hypoplasia of the earlobes (HP:0009906)2.95730124
40Abnormality of the hepatic vasculature (HP:0006707)2.92152933
41Recurrent pneumonia (HP:0006532)2.89528799
42Insulin-resistant diabetes mellitus (HP:0000831)2.85508307
43Abnormality of the renal medulla (HP:0100957)2.84009852
44Impulsivity (HP:0100710)2.80261491
45Renovascular hypertension (HP:0100817)2.76229038
46Progressive cerebellar ataxia (HP:0002073)2.75682121
47Facial shape deformation (HP:0011334)2.75115678
48Potter facies (HP:0002009)2.75115678
49Optic neuritis (HP:0100653)2.73543303
50Retrobulbar optic neuritis (HP:0100654)2.73543303
51Tubulointerstitial nephritis (HP:0001970)2.69561835
52Absent frontal sinuses (HP:0002688)2.68891200
53Disinhibition (HP:0000734)2.65092537
54Tubular atrophy (HP:0000092)2.58348711
55Abnormal rod and cone electroretinograms (HP:0008323)2.53810543
56Subcapsular cataract (HP:0000523)2.53260102
57Orchitis (HP:0100796)2.48976387
58Progressive hearing impairment (HP:0001730)2.44886216
59Peritonitis (HP:0002586)2.42975140
60Abnormality of the costochondral junction (HP:0000919)2.38194094
61Systemic lupus erythematosus (HP:0002725)2.37743241
62Enlarged epiphyses (HP:0010580)2.37600659
63Chronic obstructive pulmonary disease (HP:0006510)2.37059138
64Obstructive lung disease (HP:0006536)2.37059138
65Spastic tetraparesis (HP:0001285)2.36031106
66J-shaped sella turcica (HP:0002680)2.31652930
67Recurrent gram-negative bacterial infections (HP:0005420)2.30791993
68Tubulointerstitial abnormality (HP:0001969)2.22743578
69Myositis (HP:0100614)2.18366781
70Deformed sella turcica (HP:0002681)2.18146549
71Azoospermia (HP:0000027)2.15333146
72Heterotopia (HP:0002282)2.11433626
73Abnormality of potassium homeostasis (HP:0011042)2.10707017
74Thick nail (HP:0001805)2.10652718
75Increased IgE level (HP:0003212)2.08057330
76Hypertriglyceridemia (HP:0002155)2.06632273
77Glomerulopathy (HP:0100820)2.02119855
78Eczematoid dermatitis (HP:0000976)2.02116292
79Upper motor neuron abnormality (HP:0002127)2.01269306
80Dynein arm defect of respiratory motile cilia (HP:0012255)11.9635647
81Absent/shortened dynein arms (HP:0200106)11.9635647
82Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.5107548
83Asymmetric septal hypertrophy (HP:0001670)1.99969615
84Hemorrhage of the eye (HP:0011885)1.99631403
85Loss of speech (HP:0002371)1.98807240
86Generalized aminoaciduria (HP:0002909)1.98614502
87Hyperuricemia (HP:0002149)1.98568960
88Increased purine levels (HP:0004368)1.98568960
89Abnormal urine output (HP:0012590)1.98210771
90Ventricular tachycardia (HP:0004756)1.97907488
91Slow saccadic eye movements (HP:0000514)1.97707267
92Stomatitis (HP:0010280)1.94077338
93Aplasia/Hypoplasia of the thymus (HP:0010515)1.93692672
94Recurrent lower respiratory tract infections (HP:0002783)1.92142572
95Chest pain (HP:0100749)1.91129556
96Amyloidosis (HP:0011034)1.90833939
97Gonadotropin excess (HP:0000837)1.89763783
98Hypercholesterolemia (HP:0003124)1.88176650
99Dyschromatopsia (HP:0007641)1.88109454
100Neurofibrillary tangles (HP:0002185)1.86603538
101Increased cerebral lipofuscin (HP:0011813)1.86117700
102Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.85784547
103Prostate neoplasm (HP:0100787)1.84383112
104Hypolipoproteinemia (HP:0010981)1.82904709
105Elevated erythrocyte sedimentation rate (HP:0003565)1.82833546
106Glomerulonephritis (HP:0000099)1.81423867
107Widely patent fontanelles and sutures (HP:0004492)1.81072853
108Osteomalacia (HP:0002749)1.79699606
109Vasculitis (HP:0002633)1.78941921
110Molar tooth sign on MRI (HP:0002419)1.77459267
111Abnormality of midbrain morphology (HP:0002418)1.77459267
112Arterial thrombosis (HP:0004420)1.76435034
113Gingival bleeding (HP:0000225)1.76230878
114Colitis (HP:0002583)1.75513260
115Meningitis (HP:0001287)1.75382257
116Choroideremia (HP:0001139)1.74693101
117Personality changes (HP:0000751)1.74393267
118Esophageal varix (HP:0002040)1.74100451
119Abnormality of renal excretion (HP:0011036)1.73305314
120Pulmonary fibrosis (HP:0002206)1.71945948
121Tubulointerstitial fibrosis (HP:0005576)1.69895648
122Hypoplastic ischia (HP:0003175)1.69791871
123Medial flaring of the eyebrow (HP:0010747)1.65933299
124Gingivitis (HP:0000230)1.65856367
125Abnormality of the sella turcica (HP:0002679)1.64029453
126Abnormality of complement system (HP:0005339)1.63721169
127Neuronal loss in central nervous system (HP:0002529)1.62613589
128Abnormal gallbladder physiology (HP:0012438)1.60960232
129Cholecystitis (HP:0001082)1.60960232
130Congenital hepatic fibrosis (HP:0002612)1.60685848
131Hypoplasia of the capital femoral epiphysis (HP:0003090)1.59961540
132Vacuolated lymphocytes (HP:0001922)1.58592518
133Abnormality of the frontal sinuses (HP:0002687)1.57907971
134Bell-shaped thorax (HP:0001591)1.55959493
135Periodontitis (HP:0000704)1.55756093
136Increased neuronal autofluorescent lipopigment (HP:0002074)1.54665514
137Oculomotor apraxia (HP:0000657)1.52901948
138Complement deficiency (HP:0004431)1.52248978
139Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.50641289
140Mediastinal lymphadenopathy (HP:0100721)1.49934699
141Cerebral inclusion bodies (HP:0100314)1.49870047
142Bile duct proliferation (HP:0001408)1.48385530
143Abnormal biliary tract physiology (HP:0012439)1.48385530
144Decreased central vision (HP:0007663)1.48160982
145Nephritis (HP:0000123)1.46881225
146Polydipsia (HP:0001959)1.46145805
147Abnormal drinking behavior (HP:0030082)1.46145805
148Recurrent skin infections (HP:0001581)1.45491135
149Hemiparesis (HP:0001269)1.44670854
150Osteolytic defects of the phalanges of the hand (HP:0009771)1.44146544
151Osteolytic defects of the hand bones (HP:0009699)1.44146544
152Abnormality of macrophages (HP:0004311)1.42236060
153Autoimmune thrombocytopenia (HP:0001973)1.41792619
154Keratoconjunctivitis sicca (HP:0001097)1.40348415
155Stage 5 chronic kidney disease (HP:0003774)1.40007647
156Nephropathy (HP:0000112)1.39730786
157Supranuclear gaze palsy (HP:0000605)1.36799181
158Abnormality of the renal cortex (HP:0011035)1.36222258
159Abnormality of glycolipid metabolism (HP:0010969)1.33071209
160Abnormality of liposaccharide metabolism (HP:0010968)1.33071209
161Abnormality of glycosphingolipid metabolism (HP:0004343)1.33071209

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.24965296
2PDK47.24965296
3TESK14.98104068
4PRKD34.84208648
5PDK24.67590968
6ICK3.83174973
7BRD43.73108436
8INSRR3.02595837
9DDR22.79868733
10PLK22.69544939
11PNCK2.59092829
12PIK3CG2.39752976
13PTK2B2.31161916
14RIPK42.16515153
15CAMK1G1.84454954
16DYRK1B1.70244166
17STK38L1.68216870
18MAP4K21.64014824
19WNK41.58217442
20MAP3K111.48317627
21TYK21.45005917
22NEK21.44235908
23KIT1.43625393
24STK381.35898519
25STK391.35264146
26TBK11.31064622
27MAP3K141.30049298
28IRAK41.27931145
29MAP4K11.20754222
30KSR21.20302716
31PDK11.12472941
32WNK11.03240148
33MAP3K11.00880960
34CDK120.95076490
35BLK0.93137525
36IKBKE0.92498401
37JAK10.90272160
38ZAP700.87695797
39TAOK30.85304888
40TNK20.81358229
41GRK60.80209776
42STK30.77875985
43CSK0.77316436
44MAP3K20.76409141
45MST1R0.76174196
46CAMK1D0.73526009
47CSF1R0.73140522
48IRAK30.69694260
49MARK20.68879671
50AKT30.68751388
51GRK70.67523251
52TXK0.66353944
53CDK60.65978011
54PDPK10.65329822
55MAP2K30.63337678
56HCK0.62677630
57IKBKB0.60219700
58ATR0.59546139
59PRKG20.59221966
60TYRO30.59041765
61IRAK10.58003067
62MAP3K50.57837335
63MAP3K30.57782013
64TTN0.56280095
65CAMK10.56019458
66MAP2K20.54123006
67MATK0.53870147
68RPS6KA20.53658621
69BRAF0.52905691
70PIM10.52112843
71RPS6KA10.50398045
72MAP2K60.49584315
73NEK90.48767198
74SGK2230.48274231
75SGK4940.48274231
76RIPK10.48208999
77PRKG10.47951113
78IRAK20.47308540
79CDK70.46893698
80MAPK150.46137055
81PRKAA20.43733839
82FES0.43319258
83EGFR0.43155351
84SYK0.43080583
85SIK20.42902377
86PAK40.42697425
87JAK30.42675895
88CAMK40.42530648
89TGFBR20.42422344
90LCK0.41308616
91RPS6KL10.39762414
92RPS6KC10.39762414
93CHUK0.39418428
94TESK20.39343660
95MAP3K130.37759712
96MTOR0.37727365
97TTK0.37681184
98MAPK10.36776331
99SGK20.36388666
100LYN0.36289510
101CHEK20.36249155
102SGK10.35719868
103PBK0.35678651
104ATM0.35638374
105MAP3K70.35453215
106MAP3K80.35314174
107FGR0.34838999
108SGK30.34805130
109DYRK30.34311725
110RPS6KA60.33639755
111MAP3K90.33618602
112TAOK10.32719491
113PRKCZ0.32595966
114EPHB10.32307612
115ERN10.32240085
116PAK10.31393488
117PAK20.31319417
118CHEK10.30372943
119MAPK80.30169217
120PTK60.29908949
121MOS0.29800431
122CAMKK10.27978280
123CDK30.27581839
124PRPF4B0.27161512
125PRKCD0.26785354
126CDK190.26642748
127PKN10.25954897
128YES10.25531087
129MARK30.24935286
130PRKCQ0.24716073
131PRKCG0.20998361
132DAPK20.20293601
133JAK20.18996806
134STK100.18610481
135CDK40.18446636
136NEK60.18027779
137ABL10.16623221
138PDGFRB0.16557232
139CCNB10.15579135
140LMTK20.15363704
141BMPR20.14977304
142BTK0.14598510
143CDC70.14298407
144PRKAA10.14175816
145FYN0.13308295
146MAPK100.13102650
147CSNK1D0.12030722
148PLK40.09731112
149ITK0.09657395
150TEC0.09255207

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosaminoglycan degradation_Homo sapiens_hsa005313.13245703
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.00093630
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.99544509
4Staphylococcus aureus infection_Homo sapiens_hsa051502.97605400
5Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.78724531
6Fatty acid biosynthesis_Homo sapiens_hsa000612.69173770
7Autoimmune thyroid disease_Homo sapiens_hsa053202.18310665
8Legionellosis_Homo sapiens_hsa051342.17342904
9Vitamin B6 metabolism_Homo sapiens_hsa007502.11759023
10Carbohydrate digestion and absorption_Homo sapiens_hsa049732.08805440
11Dorso-ventral axis formation_Homo sapiens_hsa043202.06845053
12Olfactory transduction_Homo sapiens_hsa047402.02751088
13Osteoclast differentiation_Homo sapiens_hsa043802.00346475
14Antigen processing and presentation_Homo sapiens_hsa046121.91424273
15Toll-like receptor signaling pathway_Homo sapiens_hsa046201.85652442
16B cell receptor signaling pathway_Homo sapiens_hsa046621.75833370
17Measles_Homo sapiens_hsa051621.73274024
18Influenza A_Homo sapiens_hsa051641.72064034
19Leishmaniasis_Homo sapiens_hsa051401.70094205
20Mineral absorption_Homo sapiens_hsa049781.62489894
21alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.59521937
22Viral myocarditis_Homo sapiens_hsa054161.59127652
23NF-kappa B signaling pathway_Homo sapiens_hsa040641.57173388
24Lysosome_Homo sapiens_hsa041421.56924791
25NOD-like receptor signaling pathway_Homo sapiens_hsa046211.51575215
26Tuberculosis_Homo sapiens_hsa051521.44490917
27Graft-versus-host disease_Homo sapiens_hsa053321.41854802
28Pyruvate metabolism_Homo sapiens_hsa006201.41430629
29Rheumatoid arthritis_Homo sapiens_hsa053231.41239734
30Malaria_Homo sapiens_hsa051441.41021826
31Pertussis_Homo sapiens_hsa051331.40777656
32Other glycan degradation_Homo sapiens_hsa005111.38594200
33Glucagon signaling pathway_Homo sapiens_hsa049221.38049156
34Glycerolipid metabolism_Homo sapiens_hsa005611.33942253
35Linoleic acid metabolism_Homo sapiens_hsa005911.31781570
36Salmonella infection_Homo sapiens_hsa051321.31624172
37Phagosome_Homo sapiens_hsa041451.29914802
38PPAR signaling pathway_Homo sapiens_hsa033201.25987427
39Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.23539373
40Acute myeloid leukemia_Homo sapiens_hsa052211.21733703
41Toxoplasmosis_Homo sapiens_hsa051451.21486588
42Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.20163133
43Collecting duct acid secretion_Homo sapiens_hsa049661.17646456
44Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.16914453
45Fructose and mannose metabolism_Homo sapiens_hsa000511.12234967
46Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.11971258
47Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.09132566
48Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.07683913
49Fatty acid degradation_Homo sapiens_hsa000711.02129590
50Glycerophospholipid metabolism_Homo sapiens_hsa005641.00982513
51Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.99864567
52TNF signaling pathway_Homo sapiens_hsa046680.99403190
53Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.97100647
54Propanoate metabolism_Homo sapiens_hsa006400.96669219
55Fanconi anemia pathway_Homo sapiens_hsa034600.96494240
56Asthma_Homo sapiens_hsa053100.95983548
57RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.90366041
58Herpes simplex infection_Homo sapiens_hsa051680.90216726
59Allograft rejection_Homo sapiens_hsa053300.87229288
60Selenocompound metabolism_Homo sapiens_hsa004500.86379732
61Pentose phosphate pathway_Homo sapiens_hsa000300.86189625
62Adipocytokine signaling pathway_Homo sapiens_hsa049200.85934854
63Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.83299445
64Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.82643828
65Platelet activation_Homo sapiens_hsa046110.80775500
66Renin-angiotensin system_Homo sapiens_hsa046140.80741817
67Endocytosis_Homo sapiens_hsa041440.80356570
68Fatty acid metabolism_Homo sapiens_hsa012120.78522919
69Type II diabetes mellitus_Homo sapiens_hsa049300.78442999
70Complement and coagulation cascades_Homo sapiens_hsa046100.78280778
71Jak-STAT signaling pathway_Homo sapiens_hsa046300.77546181
72Ether lipid metabolism_Homo sapiens_hsa005650.73834486
73Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.73782400
74AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.70620280
75Oocyte meiosis_Homo sapiens_hsa041140.70534429
76Primary immunodeficiency_Homo sapiens_hsa053400.70482937
77Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.68200519
78ABC transporters_Homo sapiens_hsa020100.67472131
79Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.67158206
80African trypanosomiasis_Homo sapiens_hsa051430.66288203
81Phosphatidylinositol signaling system_Homo sapiens_hsa040700.66284888
82T cell receptor signaling pathway_Homo sapiens_hsa046600.63802481
83Prolactin signaling pathway_Homo sapiens_hsa049170.62924265
84Non-small cell lung cancer_Homo sapiens_hsa052230.61914502
85Inositol phosphate metabolism_Homo sapiens_hsa005620.60964381
86Apoptosis_Homo sapiens_hsa042100.60851935
87Intestinal immune network for IgA production_Homo sapiens_hsa046720.60735940
88Caffeine metabolism_Homo sapiens_hsa002320.60337075
89Sphingolipid metabolism_Homo sapiens_hsa006000.60290043
90Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.58564890
91Taste transduction_Homo sapiens_hsa047420.58227183
92Type I diabetes mellitus_Homo sapiens_hsa049400.57968524
93MAPK signaling pathway_Homo sapiens_hsa040100.57410091
94Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.57323515
95Renin secretion_Homo sapiens_hsa049240.57126352
96Hematopoietic cell lineage_Homo sapiens_hsa046400.56256378
97Shigellosis_Homo sapiens_hsa051310.55619675
98Morphine addiction_Homo sapiens_hsa050320.52644011
99Sphingolipid signaling pathway_Homo sapiens_hsa040710.50901255
100cAMP signaling pathway_Homo sapiens_hsa040240.49595027
101Transcriptional misregulation in cancer_Homo sapiens_hsa052020.49372950
102Basal transcription factors_Homo sapiens_hsa030220.48731714
103Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.48449149
104VEGF signaling pathway_Homo sapiens_hsa043700.48008690
105Salivary secretion_Homo sapiens_hsa049700.44867159
106Prion diseases_Homo sapiens_hsa050200.44544847
107Long-term potentiation_Homo sapiens_hsa047200.43913941
108Hepatitis C_Homo sapiens_hsa051600.43206210
109Calcium signaling pathway_Homo sapiens_hsa040200.42366989
110Pentose and glucuronate interconversions_Homo sapiens_hsa000400.42309879
111Epstein-Barr virus infection_Homo sapiens_hsa051690.42005669
112Butanoate metabolism_Homo sapiens_hsa006500.41755494
113Phospholipase D signaling pathway_Homo sapiens_hsa040720.41539189
114Hepatitis B_Homo sapiens_hsa051610.41290015
115Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40473350
116RNA transport_Homo sapiens_hsa030130.40469850
117Chemokine signaling pathway_Homo sapiens_hsa040620.40174712
118Estrogen signaling pathway_Homo sapiens_hsa049150.39866434
119Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.39182529
120Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38388376
121mTOR signaling pathway_Homo sapiens_hsa041500.37553866
122Leukocyte transendothelial migration_Homo sapiens_hsa046700.37153821
123Fat digestion and absorption_Homo sapiens_hsa049750.37131688
124HIF-1 signaling pathway_Homo sapiens_hsa040660.35833915
125Synaptic vesicle cycle_Homo sapiens_hsa047210.35285420
126Phenylalanine metabolism_Homo sapiens_hsa003600.35203721
127Choline metabolism in cancer_Homo sapiens_hsa052310.34145201
128Viral carcinogenesis_Homo sapiens_hsa052030.32901820
129Insulin resistance_Homo sapiens_hsa049310.31437858
130FoxO signaling pathway_Homo sapiens_hsa040680.31375977
131Arachidonic acid metabolism_Homo sapiens_hsa005900.31366917
132Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31191331
133Gastric acid secretion_Homo sapiens_hsa049710.30933201

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »