

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.20154029 |
| 2 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 5.12219037 |
| 3 | positive regulation of mast cell degranulation (GO:0043306) | 5.12219037 |
| 4 | positive regulation of mast cell activation (GO:0033005) | 5.09761924 |
| 5 | response to peptidoglycan (GO:0032494) | 5.01220853 |
| 6 | neutrophil activation involved in immune response (GO:0002283) | 4.78952221 |
| 7 | regulation of mast cell degranulation (GO:0043304) | 4.61828708 |
| 8 | regulation of hypersensitivity (GO:0002883) | 4.53051017 |
| 9 | regulation of mast cell activation involved in immune response (GO:0033006) | 4.34248050 |
| 10 | regulation of mast cell activation (GO:0033003) | 4.29075551 |
| 11 | regulation of gamma-delta T cell activation (GO:0046643) | 4.23944517 |
| 12 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 4.03881868 |
| 13 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.00719696 |
| 14 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.95407555 |
| 15 | neutrophil mediated immunity (GO:0002446) | 3.84337818 |
| 16 | regulation of leukocyte degranulation (GO:0043300) | 3.81391919 |
| 17 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.77916629 |
| 18 | negative regulation of interleukin-8 production (GO:0032717) | 3.76421573 |
| 19 | negative regulation of cell killing (GO:0031342) | 3.75948877 |
| 20 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.75948877 |
| 21 | neutrophil activation (GO:0042119) | 3.75506843 |
| 22 | cellular extravasation (GO:0045123) | 3.69341048 |
| 23 | immunoglobulin mediated immune response (GO:0016064) | 3.68265972 |
| 24 | B cell receptor signaling pathway (GO:0050853) | 3.59935637 |
| 25 | negative regulation of T cell mediated immunity (GO:0002710) | 3.59504079 |
| 26 | modulation by symbiont of host immune response (GO:0052553) | 3.58459458 |
| 27 | positive regulation by symbiont of host defense response (GO:0052509) | 3.58459458 |
| 28 | modulation by symbiont of host defense response (GO:0052031) | 3.58459458 |
| 29 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.58459458 |
| 30 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.58459458 |
| 31 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.58459458 |
| 32 | cell wall macromolecule catabolic process (GO:0016998) | 3.52588235 |
| 33 | positive regulation of leukocyte degranulation (GO:0043302) | 3.48553495 |
| 34 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.47213573 |
| 35 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.45777385 |
| 36 | positive regulation of granulocyte differentiation (GO:0030854) | 3.45579842 |
| 37 | response to muramyl dipeptide (GO:0032495) | 3.39288366 |
| 38 | granulocyte activation (GO:0036230) | 3.38809215 |
| 39 | detection of other organism (GO:0098543) | 3.38802234 |
| 40 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.36371168 |
| 41 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.29896890 |
| 42 | negative regulation of interleukin-12 production (GO:0032695) | 3.27986746 |
| 43 | myeloid leukocyte mediated immunity (GO:0002444) | 3.25535034 |
| 44 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.25249642 |
| 45 | myeloid cell activation involved in immune response (GO:0002275) | 3.24427627 |
| 46 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 3.19723377 |
| 47 | detection of bacterium (GO:0016045) | 3.17019220 |
| 48 | regulation of regulated secretory pathway (GO:1903305) | 3.17005498 |
| 49 | mast cell activation (GO:0045576) | 3.15667950 |
| 50 | microglial cell activation (GO:0001774) | 3.15333440 |
| 51 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.14795223 |
| 52 | defense response to protozoan (GO:0042832) | 3.14560087 |
| 53 | positive thymic T cell selection (GO:0045059) | 3.12974586 |
| 54 | response to protozoan (GO:0001562) | 3.10390312 |
| 55 | positive regulation of B cell differentiation (GO:0045579) | 3.08939141 |
| 56 | macrophage activation involved in immune response (GO:0002281) | 3.08781007 |
| 57 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.08142419 |
| 58 | positive regulation of interleukin-17 production (GO:0032740) | 3.05695743 |
| 59 | interferon-gamma production (GO:0032609) | 3.05602670 |
| 60 | negative regulation of granulocyte differentiation (GO:0030853) | 3.01220738 |
| 61 | positive regulation of regulated secretory pathway (GO:1903307) | 3.00388658 |
| 62 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.99668551 |
| 63 | regulation of B cell differentiation (GO:0045577) | 2.96861798 |
| 64 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 2.96664039 |
| 65 | negative T cell selection (GO:0043383) | 2.92364447 |
| 66 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.92340555 |
| 67 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.92268529 |
| 68 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.92196098 |
| 69 | negative thymic T cell selection (GO:0045060) | 2.91459337 |
| 70 | germinal center formation (GO:0002467) | 2.90587303 |
| 71 | cellular response to exogenous dsRNA (GO:0071360) | 2.90013287 |
| 72 | cell wall macromolecule metabolic process (GO:0044036) | 2.88778321 |
| 73 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.87112157 |
| 74 | regulation of granulocyte differentiation (GO:0030852) | 2.86983390 |
| 75 | respiratory burst (GO:0045730) | 2.86466228 |
| 76 | mature B cell differentiation involved in immune response (GO:0002313) | 2.85073291 |
| 77 | definitive hemopoiesis (GO:0060216) | 2.84952486 |
| 78 | negative regulation of interleukin-6 production (GO:0032715) | 2.83564188 |
| 79 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.81760450 |
| 80 | L-fucose catabolic process (GO:0042355) | 2.81694691 |
| 81 | fucose catabolic process (GO:0019317) | 2.81694691 |
| 82 | L-fucose metabolic process (GO:0042354) | 2.81694691 |
| 83 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.80552323 |
| 84 | leukocyte degranulation (GO:0043299) | 2.79747861 |
| 85 | thrombin receptor signaling pathway (GO:0070493) | 2.78794757 |
| 86 | positive regulation of antigen processing and presentation (GO:0002579) | 2.77980292 |
| 87 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 2.77045616 |
| 88 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.76513766 |
| 89 | leukocyte aggregation (GO:0070486) | 2.75767190 |
| 90 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.75242593 |
| 91 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.74170574 |
| 92 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.74146283 |
| 93 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.73700370 |
| 94 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.72933824 |
| 95 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.72789302 |
| 96 | positive regulation of B cell mediated immunity (GO:0002714) | 2.72789302 |
| 97 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.71400199 |
| 98 | NIK/NF-kappaB signaling (GO:0038061) | 2.70939789 |
| 99 | B cell mediated immunity (GO:0019724) | 2.70399693 |
| 100 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.70102630 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.71407976 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.63101622 |
| 3 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.56608001 |
| 4 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.18261518 |
| 5 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.15549184 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.11463935 |
| 7 | VDR_24763502_ChIP-Seq_THP-1_Human | 3.02900155 |
| 8 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.64414698 |
| 9 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.59925268 |
| 10 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.58567808 |
| 11 | MYB_26560356_Chip-Seq_TH2_Human | 2.55184819 |
| 12 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.49395202 |
| 13 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.47907644 |
| 14 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.45271109 |
| 15 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.35721363 |
| 16 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.31343497 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.26771210 |
| 18 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.22827850 |
| 19 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.14821941 |
| 20 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.13772554 |
| 21 | MAF_26560356_Chip-Seq_TH1_Human | 2.07702009 |
| 22 | UTX_26944678_Chip-Seq_JUKART_Human | 2.07415062 |
| 23 | MYB_26560356_Chip-Seq_TH1_Human | 2.00771813 |
| 24 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.00240764 |
| 25 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.00062904 |
| 26 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.99035825 |
| 27 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.93561557 |
| 28 | MYC_22102868_ChIP-Seq_BL_Human | 1.91728338 |
| 29 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.88774978 |
| 30 | SPI1_23127762_ChIP-Seq_K562_Human | 1.86898246 |
| 31 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.81004810 |
| 32 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.79925203 |
| 33 | MAF_26560356_Chip-Seq_TH2_Human | 1.78596518 |
| 34 | GATA3_26560356_Chip-Seq_TH2_Human | 1.78060269 |
| 35 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.72079189 |
| 36 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.70549069 |
| 37 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.65906627 |
| 38 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.65737024 |
| 39 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.65272513 |
| 40 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.63577152 |
| 41 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.60367049 |
| 42 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.54117969 |
| 43 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.53281211 |
| 44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.52219708 |
| 45 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.50214544 |
| 46 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.48137310 |
| 47 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.44830816 |
| 48 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.42743521 |
| 49 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.42585125 |
| 50 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.41097418 |
| 51 | GATA1_19941826_ChIP-Seq_K562_Human | 1.39386849 |
| 52 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.37415834 |
| 53 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.34354383 |
| 54 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.33905404 |
| 55 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.33405336 |
| 56 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.31575800 |
| 57 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.29298246 |
| 58 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.27979517 |
| 59 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.25265566 |
| 60 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.24063952 |
| 61 | P300_27268052_Chip-Seq_Bcells_Human | 1.22146912 |
| 62 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.21205418 |
| 63 | P68_20966046_ChIP-Seq_HELA_Human | 1.19879175 |
| 64 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.19663829 |
| 65 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.19129740 |
| 66 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.18951961 |
| 67 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.18725912 |
| 68 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.17416559 |
| 69 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.17399450 |
| 70 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.17179331 |
| 71 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.16577110 |
| 72 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.16312713 |
| 73 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14937393 |
| 74 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.14846489 |
| 75 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.13570828 |
| 76 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.12216431 |
| 77 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.11987546 |
| 78 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.11293858 |
| 79 | ERA_21632823_ChIP-Seq_H3396_Human | 1.10909476 |
| 80 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.09369259 |
| 81 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.09344404 |
| 82 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.09195771 |
| 83 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.08805907 |
| 84 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.08803803 |
| 85 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06855155 |
| 86 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06819765 |
| 87 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.05198698 |
| 88 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.04902838 |
| 89 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.04479806 |
| 90 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04114248 |
| 91 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.03944896 |
| 92 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.03573902 |
| 93 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.01100618 |
| 94 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.00752856 |
| 95 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.99729415 |
| 96 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.98772150 |
| 97 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.98512241 |
| 98 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.97702455 |
| 99 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.96672167 |
| 100 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.96440615 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 3.86719866 |
| 2 | MP0003724_increased_susceptibility_to | 3.32089623 |
| 3 | MP0003436_decreased_susceptibility_to | 3.19519717 |
| 4 | MP0005671_abnormal_response_to | 2.97585795 |
| 5 | MP0001800_abnormal_humoral_immune | 2.91719114 |
| 6 | MP0002419_abnormal_innate_immunity | 2.88777573 |
| 7 | MP0000685_abnormal_immune_system | 2.86823697 |
| 8 | MP0002148_abnormal_hypersensitivity_rea | 2.74133764 |
| 9 | MP0005025_abnormal_response_to | 2.62480590 |
| 10 | MP0002452_abnormal_antigen_presenting | 2.58233719 |
| 11 | MP0005387_immune_system_phenotype | 2.55511470 |
| 12 | MP0001790_abnormal_immune_system | 2.55511470 |
| 13 | MP0005000_abnormal_immune_tolerance | 2.54138051 |
| 14 | MP0002723_abnormal_immune_serum | 2.53595107 |
| 15 | MP0002420_abnormal_adaptive_immunity | 2.46379166 |
| 16 | MP0003303_peritoneal_inflammation | 2.44002482 |
| 17 | MP0001819_abnormal_immune_cell | 2.42943887 |
| 18 | MP0009278_abnormal_bone_marrow | 2.42748655 |
| 19 | MP0005464_abnormal_platelet_physiology | 2.35441805 |
| 20 | MP0003172_abnormal_lysosome_physiology | 2.32328493 |
| 21 | MP0001986_abnormal_taste_sensitivity | 2.31427575 |
| 22 | MP0009785_altered_susceptibility_to | 2.29072502 |
| 23 | MP0003763_abnormal_thymus_physiology | 2.21569245 |
| 24 | MP0006082_CNS_inflammation | 2.13390621 |
| 25 | MP0002396_abnormal_hematopoietic_system | 2.10842188 |
| 26 | MP0009764_decreased_sensitivity_to | 2.04094814 |
| 27 | MP0002398_abnormal_bone_marrow | 1.93652970 |
| 28 | MP0000716_abnormal_immune_system | 1.89073780 |
| 29 | MP0002009_preneoplasia | 1.87141567 |
| 30 | MP0001545_abnormal_hematopoietic_system | 1.86713316 |
| 31 | MP0005397_hematopoietic_system_phenotyp | 1.86713316 |
| 32 | MP0000465_gastrointestinal_hemorrhage | 1.71539019 |
| 33 | MP0010155_abnormal_intestine_physiology | 1.67497852 |
| 34 | MP0000689_abnormal_spleen_morphology | 1.63322139 |
| 35 | MP0001845_abnormal_inflammatory_respons | 1.63197278 |
| 36 | MP0002405_respiratory_system_inflammati | 1.59008938 |
| 37 | MP0001533_abnormal_skeleton_physiology | 1.58504615 |
| 38 | MP0005174_abnormal_tail_pigmentation | 1.57883200 |
| 39 | MP0004947_skin_inflammation | 1.56665057 |
| 40 | MP0004381_abnormal_hair_follicle | 1.54351354 |
| 41 | MP0002722_abnormal_immune_system | 1.52057769 |
| 42 | MP0002429_abnormal_blood_cell | 1.50631426 |
| 43 | MP0002166_altered_tumor_susceptibility | 1.46907978 |
| 44 | MP0005058_abnormal_lysosome_morphology | 1.39582362 |
| 45 | MP0009333_abnormal_splenocyte_physiolog | 1.38595285 |
| 46 | MP0003828_pulmonary_edema | 1.36647131 |
| 47 | MP0008469_abnormal_protein_level | 1.36350590 |
| 48 | MP0000015_abnormal_ear_pigmentation | 1.32486574 |
| 49 | MP0004883_abnormal_blood_vessel | 1.31818854 |
| 50 | MP0003866_abnormal_defecation | 1.31633739 |
| 51 | MP0003646_muscle_fatigue | 1.30982739 |
| 52 | MP0000703_abnormal_thymus_morphology | 1.21877868 |
| 53 | MP0001853_heart_inflammation | 1.15730152 |
| 54 | MP0002933_joint_inflammation | 1.13380443 |
| 55 | MP0001873_stomach_inflammation | 1.13318388 |
| 56 | MP0008260_abnormal_autophagy | 1.11816720 |
| 57 | MP0002132_abnormal_respiratory_system | 1.10907258 |
| 58 | MP0002998_abnormal_bone_remodeling | 1.09270204 |
| 59 | MP0000858_altered_metastatic_potential | 1.09170923 |
| 60 | MP0004808_abnormal_hematopoietic_stem | 1.07017935 |
| 61 | MP0003656_abnormal_erythrocyte_physiolo | 1.04406430 |
| 62 | MP0001501_abnormal_sleep_pattern | 1.01180023 |
| 63 | MP0002006_tumorigenesis | 1.00003527 |
| 64 | MP0005075_abnormal_melanosome_morpholog | 0.99316575 |
| 65 | MP0005310_abnormal_salivary_gland | 0.97630785 |
| 66 | MP0008961_abnormal_basal_metabolism | 0.96539415 |
| 67 | MP0002928_abnormal_bile_duct | 0.94486382 |
| 68 | MP0000569_abnormal_digit_pigmentation | 0.93785191 |
| 69 | MP0005084_abnormal_gallbladder_morpholo | 0.93547454 |
| 70 | MP0004130_abnormal_muscle_cell | 0.92030337 |
| 71 | MP0003252_abnormal_bile_duct | 0.89111733 |
| 72 | MP0005164_abnormal_response_to | 0.87984641 |
| 73 | MP0005083_abnormal_biliary_tract | 0.87478096 |
| 74 | MP0005390_skeleton_phenotype | 0.86160734 |
| 75 | MP0000249_abnormal_blood_vessel | 0.84499788 |
| 76 | MP0000681_abnormal_thyroid_gland | 0.79079062 |
| 77 | MP0000343_altered_response_to | 0.77668131 |
| 78 | MP0005166_decreased_susceptibility_to | 0.77003146 |
| 79 | MP0003075_altered_response_to | 0.70227014 |
| 80 | MP0002095_abnormal_skin_pigmentation | 0.69629100 |
| 81 | MP0009840_abnormal_foam_cell | 0.69325218 |
| 82 | MP0003300_gastrointestinal_ulcer | 0.67396680 |
| 83 | MP0001663_abnormal_digestive_system | 0.67378894 |
| 84 | MP0000470_abnormal_stomach_morphology | 0.65657026 |
| 85 | MP0001851_eye_inflammation | 0.65363603 |
| 86 | MP0003191_abnormal_cellular_cholesterol | 0.64515052 |
| 87 | MP0008004_abnormal_stomach_pH | 0.63833171 |
| 88 | MP0008057_abnormal_DNA_replication | 0.62749245 |
| 89 | MP0005376_homeostasis/metabolism_phenot | 0.62347448 |
| 90 | MP0009763_increased_sensitivity_to | 0.61241081 |
| 91 | MP0008995_early_reproductive_senescence | 0.61188813 |
| 92 | MP0002876_abnormal_thyroid_physiology | 0.59794711 |
| 93 | MP0002277_abnormal_respiratory_mucosa | 0.59785758 |
| 94 | MP0005410_abnormal_fertilization | 0.59505178 |
| 95 | MP0003959_abnormal_lean_body | 0.59116511 |
| 96 | MP0003183_abnormal_peptide_metabolism | 0.58732622 |
| 97 | MP0000230_abnormal_systemic_arterial | 0.58149805 |
| 98 | MP0005535_abnormal_body_temperature | 0.57296453 |
| 99 | MP0002693_abnormal_pancreas_physiology | 0.57121802 |
| 100 | MP0003195_calcinosis | 0.56324364 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.49309760 |
| 2 | Stomatitis (HP:0010280) | 4.71266504 |
| 3 | Myositis (HP:0100614) | 4.68283361 |
| 4 | Recurrent abscess formation (HP:0002722) | 4.50376779 |
| 5 | Recurrent bacterial skin infections (HP:0005406) | 4.48574078 |
| 6 | Eczematoid dermatitis (HP:0000976) | 3.96446189 |
| 7 | Recurrent fungal infections (HP:0002841) | 3.86609112 |
| 8 | Retrobulbar optic neuritis (HP:0100654) | 3.77291873 |
| 9 | Optic neuritis (HP:0100653) | 3.77291873 |
| 10 | Abnormality of macrophages (HP:0004311) | 3.70702031 |
| 11 | Prolonged bleeding time (HP:0003010) | 3.69424176 |
| 12 | Orchitis (HP:0100796) | 3.68982875 |
| 13 | Congenital stationary night blindness (HP:0007642) | 3.64694178 |
| 14 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.43020730 |
| 15 | Recurrent cutaneous fungal infections (HP:0011370) | 3.43020730 |
| 16 | Autoimmune thrombocytopenia (HP:0001973) | 3.40813295 |
| 17 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.39267429 |
| 18 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.34695206 |
| 19 | Meningitis (HP:0001287) | 3.30623228 |
| 20 | Amyloidosis (HP:0011034) | 3.29642172 |
| 21 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.25354930 |
| 22 | Increased cerebral lipofuscin (HP:0011813) | 3.23125397 |
| 23 | Stomach cancer (HP:0012126) | 3.18769509 |
| 24 | Recurrent skin infections (HP:0001581) | 3.12854603 |
| 25 | Encephalitis (HP:0002383) | 3.12556939 |
| 26 | Spontaneous hematomas (HP:0007420) | 3.06223902 |
| 27 | Increased serum ferritin (HP:0003281) | 2.99372111 |
| 28 | Vasculitis (HP:0002633) | 2.97548970 |
| 29 | Increased IgE level (HP:0003212) | 2.96786493 |
| 30 | Mediastinal lymphadenopathy (HP:0100721) | 2.96033848 |
| 31 | Chronic obstructive pulmonary disease (HP:0006510) | 2.91747119 |
| 32 | Obstructive lung disease (HP:0006536) | 2.91747119 |
| 33 | Agammaglobulinemia (HP:0004432) | 2.91010266 |
| 34 | Petechiae (HP:0000967) | 2.87984615 |
| 35 | Panhypogammaglobulinemia (HP:0003139) | 2.84084573 |
| 36 | Acute lymphatic leukemia (HP:0006721) | 2.81864312 |
| 37 | Keratoconjunctivitis sicca (HP:0001097) | 2.76837379 |
| 38 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.76738047 |
| 39 | Epistaxis (HP:0000421) | 2.76036177 |
| 40 | Recurrent viral infections (HP:0004429) | 2.76003015 |
| 41 | Attenuation of retinal blood vessels (HP:0007843) | 2.75961872 |
| 42 | Leukocytosis (HP:0001974) | 2.73261609 |
| 43 | Inflammation of the large intestine (HP:0002037) | 2.72897452 |
| 44 | Keratoconjunctivitis (HP:0001096) | 2.72712037 |
| 45 | Hemoptysis (HP:0002105) | 2.70609622 |
| 46 | Abnormality of T cell physiology (HP:0011840) | 2.69251804 |
| 47 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.69139705 |
| 48 | Abnormality of T cells (HP:0002843) | 2.66891054 |
| 49 | Abnormality of iron homeostasis (HP:0011031) | 2.62894635 |
| 50 | Abnormality of B cell number (HP:0010975) | 2.62582558 |
| 51 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.60797109 |
| 52 | Gastrointestinal inflammation (HP:0004386) | 2.56281500 |
| 53 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.51979853 |
| 54 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.51979853 |
| 55 | Abnormality of glycolipid metabolism (HP:0010969) | 2.51979853 |
| 56 | Pulmonary infiltrates (HP:0002113) | 2.47269341 |
| 57 | Abnormality of T cell number (HP:0011839) | 2.47034922 |
| 58 | Clumsiness (HP:0002312) | 2.45073215 |
| 59 | Urticaria (HP:0001025) | 2.43742672 |
| 60 | Prostate neoplasm (HP:0100787) | 2.43414185 |
| 61 | Cellulitis (HP:0100658) | 2.43340198 |
| 62 | Gastrointestinal infarctions (HP:0005244) | 2.42565872 |
| 63 | Granulocytopenia (HP:0001913) | 2.39274786 |
| 64 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.37116392 |
| 65 | Episodic fever (HP:0001954) | 2.35511562 |
| 66 | T lymphocytopenia (HP:0005403) | 2.34527921 |
| 67 | Autoimmune hemolytic anemia (HP:0001890) | 2.30541102 |
| 68 | Pustule (HP:0200039) | 2.29856744 |
| 69 | Purpura (HP:0000979) | 2.28324302 |
| 70 | Abnormality of the prostate (HP:0008775) | 2.28231748 |
| 71 | Increased IgM level (HP:0003496) | 2.28209939 |
| 72 | Chest pain (HP:0100749) | 2.23708855 |
| 73 | Colitis (HP:0002583) | 2.22423105 |
| 74 | Hypochromic anemia (HP:0001931) | 2.20238196 |
| 75 | Eosinophilia (HP:0001880) | 2.17632164 |
| 76 | Gingival bleeding (HP:0000225) | 2.11444887 |
| 77 | Genetic anticipation (HP:0003743) | 2.11410765 |
| 78 | Thrombocytosis (HP:0001894) | 2.11147685 |
| 79 | Abnormality of the pleura (HP:0002103) | 2.09222128 |
| 80 | Constricted visual fields (HP:0001133) | 2.04870948 |
| 81 | IgG deficiency (HP:0004315) | 2.03994205 |
| 82 | Facial diplegia (HP:0001349) | 2.01635400 |
| 83 | Skin rash (HP:0000988) | 2.01053384 |
| 84 | Osteomyelitis (HP:0002754) | 1.99833256 |
| 85 | Pulmonary embolism (HP:0002204) | 1.99319462 |
| 86 | Macular degeneration (HP:0000608) | 1.97107882 |
| 87 | Arterial thrombosis (HP:0004420) | 1.96320621 |
| 88 | Vacuolated lymphocytes (HP:0001922) | 1.91812109 |
| 89 | Anorexia (HP:0002039) | 1.91674938 |
| 90 | Abnormality of eosinophils (HP:0001879) | 1.90738641 |
| 91 | Chronic diarrhea (HP:0002028) | 1.88950669 |
| 92 | Chronic sinusitis (HP:0011109) | 1.87828890 |
| 93 | Cheilitis (HP:0100825) | 1.86705947 |
| 94 | Decreased central vision (HP:0007663) | 1.86148067 |
| 95 | Protruding tongue (HP:0010808) | 1.85089662 |
| 96 | Abolished electroretinogram (ERG) (HP:0000550) | 1.84615485 |
| 97 | Amelogenesis imperfecta (HP:0000705) | 1.84601795 |
| 98 | Dysostosis multiplex (HP:0000943) | 1.84431969 |
| 99 | Impaired platelet aggregation (HP:0003540) | 1.83576314 |
| 100 | Abnormal platelet function (HP:0011869) | 1.83576314 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 3.96377718 |
| 2 | TESK2 | 3.78850081 |
| 3 | MAP4K1 | 3.30161344 |
| 4 | TXK | 2.82736674 |
| 5 | TAOK3 | 2.73582065 |
| 6 | BLK | 2.68519557 |
| 7 | FES | 2.46476080 |
| 8 | BTK | 2.31866948 |
| 9 | GRK6 | 2.26034386 |
| 10 | MAPK15 | 2.25404583 |
| 11 | ZAP70 | 2.19430060 |
| 12 | TEC | 2.19039651 |
| 13 | IRAK4 | 2.08329492 |
| 14 | SYK | 2.03344079 |
| 15 | KIT | 2.01482326 |
| 16 | MAP3K14 | 1.88127952 |
| 17 | TYK2 | 1.83526487 |
| 18 | ITK | 1.82523483 |
| 19 | BMPR2 | 1.78884754 |
| 20 | TNK2 | 1.77602078 |
| 21 | IKBKB | 1.69619195 |
| 22 | MAP3K11 | 1.64642367 |
| 23 | HCK | 1.61848201 |
| 24 | IKBKE | 1.60751570 |
| 25 | CSF1R | 1.60293719 |
| 26 | TBK1 | 1.59077822 |
| 27 | MAP2K2 | 1.56073593 |
| 28 | ADRBK2 | 1.54057168 |
| 29 | TRPM7 | 1.49393804 |
| 30 | FRK | 1.43790111 |
| 31 | LYN | 1.36861270 |
| 32 | CSK | 1.31671637 |
| 33 | GRK1 | 1.29118539 |
| 34 | MAP2K3 | 1.24359449 |
| 35 | CDK19 | 1.23557594 |
| 36 | ERN1 | 1.20299055 |
| 37 | JAK3 | 1.17752019 |
| 38 | LCK | 1.15242547 |
| 39 | TLK1 | 1.09190701 |
| 40 | MAPK7 | 1.07777120 |
| 41 | MAP3K6 | 1.06007726 |
| 42 | KDR | 1.05499311 |
| 43 | MARK3 | 1.02289536 |
| 44 | IRAK1 | 0.98321509 |
| 45 | ACVR1B | 0.96830064 |
| 46 | MATK | 0.95283846 |
| 47 | HIPK2 | 0.95027540 |
| 48 | MAP3K1 | 0.94252176 |
| 49 | PIK3CG | 0.88235099 |
| 50 | JAK2 | 0.81241338 |
| 51 | MAP3K13 | 0.81030981 |
| 52 | DAPK2 | 0.79969119 |
| 53 | ZAK | 0.77701575 |
| 54 | RPS6KA6 | 0.77591204 |
| 55 | CHUK | 0.76473716 |
| 56 | FLT3 | 0.73621357 |
| 57 | GRK7 | 0.68303100 |
| 58 | MAP4K2 | 0.67827532 |
| 59 | PRKD2 | 0.67675280 |
| 60 | JAK1 | 0.66898686 |
| 61 | WNK4 | 0.65983297 |
| 62 | PRKCQ | 0.64951619 |
| 63 | PIM1 | 0.63756290 |
| 64 | MAP2K6 | 0.62794601 |
| 65 | ADRBK1 | 0.59330796 |
| 66 | MOS | 0.58717767 |
| 67 | RPS6KL1 | 0.58317348 |
| 68 | RPS6KC1 | 0.58317348 |
| 69 | CAMKK2 | 0.56411885 |
| 70 | PRPF4B | 0.56299061 |
| 71 | SIK3 | 0.54373531 |
| 72 | MARK2 | 0.54273545 |
| 73 | CAMK1D | 0.52564282 |
| 74 | PDPK1 | 0.51771203 |
| 75 | IRAK2 | 0.51555814 |
| 76 | FGR | 0.50754851 |
| 77 | PDK1 | 0.50521432 |
| 78 | ABL1 | 0.50020870 |
| 79 | MAPK12 | 0.49647274 |
| 80 | SIK2 | 0.49082220 |
| 81 | MAPKAPK3 | 0.49053126 |
| 82 | DYRK1B | 0.47604860 |
| 83 | MAPK4 | 0.47311619 |
| 84 | CDK6 | 0.44957453 |
| 85 | CDK12 | 0.44438841 |
| 86 | CAMKK1 | 0.43901245 |
| 87 | MAP3K5 | 0.42953230 |
| 88 | MAPKAPK2 | 0.40088695 |
| 89 | MUSK | 0.39393977 |
| 90 | MAPK3 | 0.38498785 |
| 91 | OXSR1 | 0.38478970 |
| 92 | IRAK3 | 0.36480176 |
| 93 | TRIB3 | 0.35953691 |
| 94 | RPS6KA4 | 0.35795259 |
| 95 | RPS6KA5 | 0.31732335 |
| 96 | MAP3K7 | 0.31670019 |
| 97 | DYRK3 | 0.30849019 |
| 98 | CAMK4 | 0.30375189 |
| 99 | PTK2B | 0.28741462 |
| 100 | PRKD1 | 0.27719268 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 3.05949622 |
| 2 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.86097765 |
| 3 | Leishmaniasis_Homo sapiens_hsa05140 | 2.68752407 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.40419562 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.36532013 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.34260980 |
| 7 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.33174923 |
| 8 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.32212159 |
| 9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.29394903 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.20626552 |
| 11 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.12234600 |
| 12 | Other glycan degradation_Homo sapiens_hsa00511 | 1.99145181 |
| 13 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.96291651 |
| 14 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.92801279 |
| 15 | Tuberculosis_Homo sapiens_hsa05152 | 1.88458830 |
| 16 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.73664712 |
| 17 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.71628269 |
| 18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.70398102 |
| 19 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.66735007 |
| 20 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.66254286 |
| 21 | Malaria_Homo sapiens_hsa05144 | 1.64285983 |
| 22 | Legionellosis_Homo sapiens_hsa05134 | 1.61040325 |
| 23 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.58484131 |
| 24 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.56475842 |
| 25 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.53723266 |
| 26 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.51827873 |
| 27 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.45059127 |
| 28 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.42590300 |
| 29 | Platelet activation_Homo sapiens_hsa04611 | 1.38988117 |
| 30 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.38095742 |
| 31 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.37386282 |
| 32 | Influenza A_Homo sapiens_hsa05164 | 1.30916419 |
| 33 | Phototransduction_Homo sapiens_hsa04744 | 1.29841832 |
| 34 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.24880467 |
| 35 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.22860152 |
| 36 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.22675820 |
| 37 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.21197562 |
| 38 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.19918661 |
| 39 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.19074417 |
| 40 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.16671649 |
| 41 | Viral myocarditis_Homo sapiens_hsa05416 | 1.15319866 |
| 42 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.15107073 |
| 43 | Lysosome_Homo sapiens_hsa04142 | 1.11831334 |
| 44 | Pertussis_Homo sapiens_hsa05133 | 1.09969263 |
| 45 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.07762589 |
| 46 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.07619045 |
| 47 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.04350815 |
| 48 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.03990238 |
| 49 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.01649263 |
| 50 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.01522378 |
| 51 | Measles_Homo sapiens_hsa05162 | 0.96634117 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.96298452 |
| 53 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.89123053 |
| 54 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.87635576 |
| 55 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.83190902 |
| 56 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.81071469 |
| 57 | Hepatitis B_Homo sapiens_hsa05161 | 0.79804536 |
| 58 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.79581441 |
| 59 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.76538784 |
| 60 | ABC transporters_Homo sapiens_hsa02010 | 0.73678567 |
| 61 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.72866366 |
| 62 | Phagosome_Homo sapiens_hsa04145 | 0.70591700 |
| 63 | Salmonella infection_Homo sapiens_hsa05132 | 0.69299032 |
| 64 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.67973726 |
| 65 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.67657451 |
| 66 | Shigellosis_Homo sapiens_hsa05131 | 0.67099733 |
| 67 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.66578064 |
| 68 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.65250696 |
| 69 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.62299655 |
| 70 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.59123824 |
| 71 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.58443460 |
| 72 | Apoptosis_Homo sapiens_hsa04210 | 0.57529631 |
| 73 | Morphine addiction_Homo sapiens_hsa05032 | 0.52166301 |
| 74 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.48597738 |
| 75 | Olfactory transduction_Homo sapiens_hsa04740 | 0.47234153 |
| 76 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.46288008 |
| 77 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.45088189 |
| 78 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.43453492 |
| 79 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.41708949 |
| 80 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.41461823 |
| 81 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40640350 |
| 82 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.40165212 |
| 83 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.39645029 |
| 84 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.38327508 |
| 85 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38193263 |
| 86 | Sulfur relay system_Homo sapiens_hsa04122 | 0.37666487 |
| 87 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.37426851 |
| 88 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.37314183 |
| 89 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.35772794 |
| 90 | Salivary secretion_Homo sapiens_hsa04970 | 0.35253539 |
| 91 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.34719320 |
| 92 | HTLV-I infection_Homo sapiens_hsa05166 | 0.34614386 |
| 93 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.33279769 |
| 94 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.32992348 |
| 95 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.32787529 |
| 96 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.30609166 |
| 97 | Endocytosis_Homo sapiens_hsa04144 | 0.28990160 |
| 98 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.28926610 |
| 99 | Histidine metabolism_Homo sapiens_hsa00340 | 0.28684451 |
| 100 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.26420941 |

