MSANTD3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell adhesion mediated by integrin (GO:0033627)5.23661110
2regulation of vitamin D biosynthetic process (GO:0060556)4.89279187
3DNA unwinding involved in DNA replication (GO:0006268)4.45625918
4substrate-dependent cell migration (GO:0006929)4.45090566
5formation of translation preinitiation complex (GO:0001731)4.30326875
6protein neddylation (GO:0045116)4.30293773
7DNA strand elongation involved in DNA replication (GO:0006271)4.27649251
8DNA replication initiation (GO:0006270)4.09807058
9regulation of gene silencing by RNA (GO:0060966)4.06120315
10regulation of posttranscriptional gene silencing (GO:0060147)4.06120315
11regulation of gene silencing by miRNA (GO:0060964)4.06120315
12DNA strand elongation (GO:0022616)4.05909835
13paraxial mesoderm development (GO:0048339)4.00078395
14DNA replication-dependent nucleosome assembly (GO:0006335)3.95340253
15DNA replication-dependent nucleosome organization (GO:0034723)3.95340253
16mitotic metaphase plate congression (GO:0007080)3.90331854
17regulation of early endosome to late endosome transport (GO:2000641)3.89241095
18establishment of integrated proviral latency (GO:0075713)3.87009640
19protein localization to kinetochore (GO:0034501)3.85922260
20maturation of SSU-rRNA (GO:0030490)3.82163149
21nuclear pore organization (GO:0006999)3.74411261
22telomere maintenance via semi-conservative replication (GO:0032201)3.73994672
23protein localization to endosome (GO:0036010)3.73350044
24regulation of integrin-mediated signaling pathway (GO:2001044)3.71586674
25mitotic nuclear envelope disassembly (GO:0007077)3.63433295
26positive regulation of heat generation (GO:0031652)3.61419514
27ganglion development (GO:0061548)3.58868942
28skin morphogenesis (GO:0043589)3.58714960
29nucleobase biosynthetic process (GO:0046112)3.57384751
30DNA replication checkpoint (GO:0000076)3.57076481
31peptidyl-arginine omega-N-methylation (GO:0035247)3.51091416
32chromatin remodeling at centromere (GO:0031055)3.48274337
33nuclear pore complex assembly (GO:0051292)3.47916730
34histone arginine methylation (GO:0034969)3.45673987
35IMP biosynthetic process (GO:0006188)3.44391802
36regulation of vitamin metabolic process (GO:0030656)3.44168954
37positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.41840554
38CENP-A containing nucleosome assembly (GO:0034080)3.41141237
39mesodermal cell differentiation (GO:0048333)3.40389308
40nuclear envelope disassembly (GO:0051081)3.39057693
41membrane disassembly (GO:0030397)3.39057693
42protein localization to chromosome, centromeric region (GO:0071459)3.38258145
43regulation of fever generation (GO:0031620)3.36958317
44ribosomal small subunit assembly (GO:0000028)3.36687943
45metaphase plate congression (GO:0051310)3.36254279
46spliceosomal snRNP assembly (GO:0000387)3.33976954
47decidualization (GO:0046697)3.31071240
48negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.29985467
49negative regulation of nitric oxide biosynthetic process (GO:0045019)3.28669578
50regulation of helicase activity (GO:0051095)3.28171823
51regulation of membrane protein ectodomain proteolysis (GO:0051043)3.27030196
52telomere maintenance via recombination (GO:0000722)3.25843841
53IMP metabolic process (GO:0046040)3.23494807
54telomere maintenance via telomere lengthening (GO:0010833)3.22961340
55kinetochore organization (GO:0051383)3.22207897
56DNA replication-independent nucleosome assembly (GO:0006336)3.19989853
57DNA replication-independent nucleosome organization (GO:0034724)3.19989853
58DNA double-strand break processing (GO:0000729)3.19985923
59negative regulation of chromosome segregation (GO:0051985)3.19365023
60kinetochore assembly (GO:0051382)3.18882847
61purine nucleobase biosynthetic process (GO:0009113)3.18773893
62nucleotide-excision repair, DNA gap filling (GO:0006297)3.18156530
63negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.16537654
64negative regulation of sister chromatid segregation (GO:0033046)3.16537654
65negative regulation of mitotic sister chromatid separation (GO:2000816)3.16537654
66negative regulation of mitotic sister chromatid segregation (GO:0033048)3.16537654
67sphingosine metabolic process (GO:0006670)3.16289300
68adhesion of symbiont to host cell (GO:0044650)3.15263229
69virion attachment to host cell (GO:0019062)3.15263229
70ribosome biogenesis (GO:0042254)3.15181607
71regulation of chronic inflammatory response (GO:0002676)3.13227160
72mitotic spindle checkpoint (GO:0071174)3.13057847
73mitotic spindle assembly checkpoint (GO:0007094)3.12546867
74mitotic recombination (GO:0006312)3.12421966
75heparan sulfate proteoglycan biosynthetic process (GO:0015012)3.12109613
76spindle checkpoint (GO:0031577)3.11288519
77regulation of histone H3-K9 methylation (GO:0051570)3.11244521
78regulation of mononuclear cell migration (GO:0071675)3.10861396
79negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.09934873
80establishment of chromosome localization (GO:0051303)3.09932776
81regulation of cytokine secretion involved in immune response (GO:0002739)3.08882087
82spindle assembly checkpoint (GO:0071173)3.08611301
83positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.07904660
84ribonucleoprotein complex biogenesis (GO:0022613)3.07840391
85attachment of spindle microtubules to kinetochore (GO:0008608)3.07322564
86peptidyl-arginine N-methylation (GO:0035246)3.06623316
87peptidyl-arginine methylation (GO:0018216)3.06623316
88endocytic recycling (GO:0032456)3.05792682
89positive regulation of p38MAPK cascade (GO:1900745)3.05708064
90ribosome assembly (GO:0042255)3.04055662
91DNA duplex unwinding (GO:0032508)3.03840968
92regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.03556523
93DNA geometric change (GO:0032392)3.02384649
94negative regulation of release of cytochrome c from mitochondria (GO:0090201)3.01865758
95viral transcription (GO:0019083)3.01516343
96translational termination (GO:0006415)3.01012839
97negative regulation of RNA splicing (GO:0033119)3.00323873
98regulation of mitotic metaphase/anaphase transition (GO:0030071)2.99664088
99ribosomal small subunit biogenesis (GO:0042274)2.99441046
100ribosomal large subunit biogenesis (GO:0042273)2.98532595
101regulation of podosome assembly (GO:0071801)2.96881720
102cellular response to vitamin D (GO:0071305)2.96304933
103regulation of nuclear cell cycle DNA replication (GO:0033262)2.96269811
104translational initiation (GO:0006413)2.95330479
105regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.94945429
106histone exchange (GO:0043486)2.94418244
107pre-miRNA processing (GO:0031054)2.94148203
108regulation of centrosome cycle (GO:0046605)2.94033724
109somatic diversification of immune receptors via somatic mutation (GO:0002566)2.93884576
110somatic hypermutation of immunoglobulin genes (GO:0016446)2.93884576
111response to magnesium ion (GO:0032026)2.91947124
112cellular response to arsenic-containing substance (GO:0071243)2.91363565
113spliceosomal complex assembly (GO:0000245)2.90462214
114histone H2A acetylation (GO:0043968)2.90415247
115regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.90046501
116epithelial cell-cell adhesion (GO:0090136)2.89647891
117regulation of mitotic sister chromatid separation (GO:0010965)2.89519375
118regulation of mitotic sister chromatid segregation (GO:0033047)2.89519375
119regulation of sister chromatid segregation (GO:0033045)2.89519375
120chondrocyte proliferation (GO:0035988)2.89052437
121polyamine biosynthetic process (GO:0006596)2.88458037
122regulation of chromosome segregation (GO:0051983)2.88133903
123dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.88030608
124endodermal cell differentiation (GO:0035987)2.87176772
125negative regulation of histone methylation (GO:0031061)2.86052807
126fibrinolysis (GO:0042730)2.86045188
127mitotic chromosome condensation (GO:0007076)2.85844886
128positive regulation of chemokine biosynthetic process (GO:0045080)2.85734779
129negative regulation of focal adhesion assembly (GO:0051895)2.85443947
130negative regulation of cell junction assembly (GO:1901889)2.85443947
131negative regulation of adherens junction organization (GO:1903392)2.85443947
132negative regulation of mRNA processing (GO:0050686)2.84926095
133negative regulation of monooxygenase activity (GO:0032769)2.84655888
134negative regulation of lipid storage (GO:0010888)2.83852772
135cyclooxygenase pathway (GO:0019371)2.83264501
136folic acid-containing compound biosynthetic process (GO:0009396)2.83036732
137mitotic sister chromatid segregation (GO:0000070)2.82149278
138regulation of heat generation (GO:0031650)2.81776983
139negative regulation of nitric-oxide synthase activity (GO:0051001)2.80865812
140mRNA splicing, via spliceosome (GO:0000398)2.80397515
141RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.80397515
142RNA splicing, via transesterification reactions (GO:0000375)2.80397233
143mismatch repair (GO:0006298)2.79807903
144regulation of centriole replication (GO:0046599)2.79609261
145endosome to melanosome transport (GO:0035646)2.79541436
146endosome to pigment granule transport (GO:0043485)2.79541436
147intra-S DNA damage checkpoint (GO:0031573)2.79286866
148heterochromatin organization (GO:0070828)2.79233410
149regulation of sister chromatid cohesion (GO:0007063)2.78624472
150transcription-coupled nucleotide-excision repair (GO:0006283)2.77731638
151retina vasculature morphogenesis in camera-type eye (GO:0061299)2.73471284
152nucleobase-containing small molecule interconversion (GO:0015949)2.72582238
153negative regulation of platelet activation (GO:0010544)2.71498500
154purine nucleotide salvage (GO:0032261)2.71019607
155adenosine receptor signaling pathway (GO:0001973)2.68495970
156positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.68480024
157negative regulation of JAK-STAT cascade (GO:0046426)2.67850865
158proteasome assembly (GO:0043248)2.67348239
159platelet dense granule organization (GO:0060155)2.65935292
160regulation of integrin activation (GO:0033623)2.64530748
161regulation of nitric oxide biosynthetic process (GO:0045428)2.64492169
162negative regulation of homotypic cell-cell adhesion (GO:0034111)2.63419438
163cellular response to vitamin (GO:0071295)2.62926337
164positive regulation of protein autophosphorylation (GO:0031954)2.62349017
165hyaluronan catabolic process (GO:0030214)2.61442572
166glial cell migration (GO:0008347)2.58936771
167stress fiber assembly (GO:0043149)2.58827556
168regulation of T-helper 1 cell differentiation (GO:0045625)2.57964078
169axon extension involved in axon guidance (GO:0048846)2.56158266
170neuron projection extension involved in neuron projection guidance (GO:1902284)2.56158266
171regulation of immune response to tumor cell (GO:0002837)2.54526904
172regulation of response to tumor cell (GO:0002834)2.54526904
173positive regulation of response to tumor cell (GO:0002836)2.54526904
174positive regulation of immune response to tumor cell (GO:0002839)2.54526904
175glycosphingolipid catabolic process (GO:0046479)2.54315660
176protein maturation by protein folding (GO:0022417)2.53676856
177sequestering of actin monomers (GO:0042989)2.53370893
178cellular copper ion homeostasis (GO:0006878)2.52560600
179positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.51131041
180diol metabolic process (GO:0034311)2.49075703
181negative regulation of mitochondrion organization (GO:0010823)2.46232112
182regulation of immunoglobulin secretion (GO:0051023)2.44864114
183positive regulation of endothelial cell apoptotic process (GO:2000353)2.44351542
184chronic inflammatory response (GO:0002544)2.40990336
185adhesion of symbiont to host (GO:0044406)2.39297462
186response to vitamin D (GO:0033280)2.36842604
187sphingoid metabolic process (GO:0046519)2.36453144
188regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.35823298
189positive regulation of nitric oxide biosynthetic process (GO:0045429)2.33027215
190positive regulation of neurotransmitter secretion (GO:0001956)2.31549823
191de novo protein folding (GO:0006458)2.29293136
192wound healing, spreading of epidermal cells (GO:0035313)2.29161707
193membrane lipid catabolic process (GO:0046466)2.28531129
194cellular response to thyroid hormone stimulus (GO:0097067)2.27759418
195peptidyl-proline hydroxylation (GO:0019511)2.27127563
196cellular protein complex localization (GO:0034629)2.25727747
197monocyte chemotaxis (GO:0002548)2.25592385
198barbed-end actin filament capping (GO:0051016)2.25111056
199negative regulation of protein localization to cell surface (GO:2000009)2.23913989
200negative regulation of protein localization to plasma membrane (GO:1903077)2.23848875

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.91259709
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.59275376
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.86128665
4SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.78463273
5TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.75344219
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.61277280
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.24823320
8MYC_19079543_ChIP-ChIP_MESCs_Mouse3.22717364
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.11491828
10WT1_19549856_ChIP-ChIP_CCG9911_Human3.11123875
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.98580741
12BRD4_25478319_ChIP-Seq_HGPS_Human2.80464314
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.70661641
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.68495549
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.63636004
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.52663065
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.52644260
18RARG_19884340_ChIP-ChIP_MEFs_Mouse2.48601254
19KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.47615188
20KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.47615188
21KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.47615188
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.47015898
23ETS1_20019798_ChIP-Seq_JURKAT_Human2.44365344
24ATF3_23680149_ChIP-Seq_GBM1-GSC_Human2.43809661
25CJUN_26792858_Chip-Seq_BT549_Human2.38175662
26PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.37199739
27XRN2_22483619_ChIP-Seq_HELA_Human2.35582450
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.35311726
29PRDM5_23873026_ChIP-Seq_MEFs_Mouse2.33894507
30E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.33854373
31Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.32516162
32GABP_17652178_ChIP-ChIP_JURKAT_Human2.28266809
33SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.27820396
34SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.27820396
35MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.27013004
36NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.19918551
37JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.18430257
38JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.15061923
39RBPJ_22232070_ChIP-Seq_NCS_Mouse2.13917986
40CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.12416761
41POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.10234620
42MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.09620195
43KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.07164036
44JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.07066683
45E2F1_18555785_ChIP-Seq_MESCs_Mouse2.06783180
46TP63_17297297_ChIP-ChIP_HaCaT_Human2.02668111
47NRF2_20460467_ChIP-Seq_MEFs_Mouse2.01176795
48NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.01176795
49AR_21909140_ChIP-Seq_LNCAP_Human2.01009121
50MYCN_18555785_ChIP-Seq_MESCs_Mouse2.00332597
51E2F1_21310950_ChIP-Seq_MCF-7_Human2.00283433
52SOX2_18555785_ChIP-Seq_MESCs_Mouse1.98977604
53SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.98751165
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.97324436
55TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.95829351
56RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.95735251
57TP63_19390658_ChIP-ChIP_HaCaT_Human1.92184644
58NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.88256204
59POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.84883283
60SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.84565558
61TCF3_18692474_ChIP-Seq_MEFs_Mouse1.83893174
62SMAD_19615063_ChIP-ChIP_OVARY_Human1.82766695
63EGR1_19374776_ChIP-ChIP_THP-1_Human1.82017990
64POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.81603816
65TTF2_22483619_ChIP-Seq_HELA_Human1.81385697
66RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.80570175
67THAP11_20581084_ChIP-Seq_MESCs_Mouse1.78218244
68HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.72327672
69ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.69545532
70VDR_23849224_ChIP-Seq_CD4+_Human1.67331445
71MYB_21317192_ChIP-Seq_ERMYB_Mouse1.64638355
72TRIM28_21343339_ChIP-Seq_HEK293_Human1.63196520
73ZFX_18555785_ChIP-Seq_MESCs_Mouse1.62964768
74YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.62776737
75SALL4_18804426_ChIP-ChIP_XEN_Mouse1.62580171
76GABP_19822575_ChIP-Seq_HepG2_Human1.62346758
77KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.60499140
78SALL1_21062744_ChIP-ChIP_HESCs_Human1.60154250
79DCP1A_22483619_ChIP-Seq_HELA_Human1.59789235
80CLOCK_20551151_ChIP-Seq_293T_Human1.59595525
81EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.59014063
82UBF1/2_26484160_Chip-Seq_HMECs_Human1.54989537
83CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.54708017
84FOXP3_21729870_ChIP-Seq_TREG_Human1.53693999
85MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.53494402
86CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.53431306
87NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.51005980
88PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50896768
89HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.50261086
90ELK1_19687146_ChIP-ChIP_HELA_Human1.50129226
91GATA2_21666600_ChIP-Seq_HMVEC_Human1.48840091
92NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.47448960
93ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.45291464
94TCF3_18692474_ChIP-Seq_MESCs_Mouse1.43784113
95TP53_18474530_ChIP-ChIP_U2OS_Human1.42017879
96YY1_21170310_ChIP-Seq_MESCs_Mouse1.41148573
97HIF1A_21447827_ChIP-Seq_MCF-7_Human1.39864360
98ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.37535455
99CIITA_25753668_ChIP-Seq_RAJI_Human1.37352878
100IRF8_21731497_ChIP-ChIP_J774_Mouse1.35358686
101NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.34327395
102SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.32583701
103MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.32336674
104STAT3_1855785_ChIP-Seq_MESCs_Mouse1.31874335
105NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.29644933
106NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.29134620
107ATF3_27146783_Chip-Seq_COLON_Human1.29076997
108P300_27058665_Chip-Seq_ZR-75-30cells_Human1.28312918
109SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.27984726
110GATA4_21415370_ChIP-Seq_HL-1_Mouse1.27458259
111KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.24377566
112SOX17_20123909_ChIP-Seq_XEN_Mouse1.24144113
113STAT6_21828071_ChIP-Seq_BEAS2B_Human1.23411402
114KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.22509772
115ZNF263_19887448_ChIP-Seq_K562_Human1.21824583
116ELK3_25401928_ChIP-Seq_HUVEC_Human1.21233443
117ESR1_15608294_ChIP-ChIP_MCF-7_Human1.20646662
118TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.19955094
119SOX2_20726797_ChIP-Seq_SW620_Human1.19953764
120KLF4_18555785_ChIP-Seq_MESCs_Mouse1.18467401
121EP300_21415370_ChIP-Seq_HL-1_Mouse1.18404338
122REST_19997604_ChIP-ChIP_NEURONS_Mouse1.18037044
123TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.15241586
124NANOG_21062744_ChIP-ChIP_HESCs_Human1.14969781
125CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.14591835
126DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13903524
127NFI_21473784_ChIP-Seq_ESCs_Mouse1.13417608
128SOX2_18692474_ChIP-Seq_MEFs_Mouse1.12897503
129NANOG_18692474_ChIP-Seq_MEFs_Mouse1.12375961
130TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.11881293
131MYC_22102868_ChIP-Seq_BL_Human1.11816025
132PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.11136200
133HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.10629691
134FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.10034088
135TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.09793625
136MYC_18940864_ChIP-ChIP_HL60_Human1.08987977
137TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.08435450
138KDM5A_27292631_Chip-Seq_BREAST_Human1.08420525
139SOX2_16153702_ChIP-ChIP_HESCs_Human1.08360239
140SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.07741534
141SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.07423154
142ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.06468737
143PPAR_26484153_Chip-Seq_NCI-H1993_Human1.06182404
144HOXB4_20404135_ChIP-ChIP_EML_Mouse1.06140831
145NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.05224712
146NANOG_16153702_ChIP-ChIP_HESCs_Human1.05180338
147TP53_22127205_ChIP-Seq_IMR90_Human1.04875246
148FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.04855439
149WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.03910040
150OCT4_18692474_ChIP-Seq_MEFs_Mouse1.01733754
151DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.01222833
152ELF1_17652178_ChIP-ChIP_JURKAT_Human1.01050955
153ERG_20887958_ChIP-Seq_HPC-7_Mouse0.98332843
154SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97206527
155SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.96883321
156E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.96705952
157CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96290306
158CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.94688146
159NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.94305342
160SRF_21415370_ChIP-Seq_HL-1_Mouse0.94197696
161CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.93598990
162TFEB_21752829_ChIP-Seq_HELA_Human0.92662194
163POU5F1_16518401_ChIP-PET_MESCs_Mouse0.91446690
164SOX2_18692474_ChIP-Seq_MESCs_Mouse0.90663963
165BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.89431683

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005257_abnormal_intraocular_pressure3.93484985
2MP0008438_abnormal_cutaneous_collagen3.84991873
3MP0006054_spinal_hemorrhage3.70032489
4MP0004510_myositis3.65790506
5MP0010094_abnormal_chromosome_stability3.56821786
6MP0002877_abnormal_melanocyte_morpholog3.55397494
7MP0003950_abnormal_plasma_membrane3.49089348
8MP0008057_abnormal_DNA_replication3.31030676
9MP0004957_abnormal_blastocyst_morpholog3.27991112
10MP0003077_abnormal_cell_cycle3.23727081
11MP0003693_abnormal_embryo_hatching3.17922954
12MP0010030_abnormal_orbit_morphology3.15001632
13MP0003111_abnormal_nucleus_morphology3.06477331
14MP0003123_paternal_imprinting3.04861126
15MP0005058_abnormal_lysosome_morphology2.75103909
16MP0000343_altered_response_to2.67368002
17MP0003566_abnormal_cell_adhesion2.59318464
18MP0008932_abnormal_embryonic_tissue2.53608421
19MP0003303_peritoneal_inflammation2.44590240
20MP0008058_abnormal_DNA_repair2.43251545
21MP0005464_abnormal_platelet_physiology2.41124684
22MP0008007_abnormal_cellular_replicative2.39159231
23MP0001542_abnormal_bone_strength2.25705371
24MP0008877_abnormal_DNA_methylation2.25251913
25MP0008004_abnormal_stomach_pH2.19461506
26MP0009840_abnormal_foam_cell2.17731192
27MP0002653_abnormal_ependyma_morphology2.16845588
28MP0004133_heterotaxia2.13263166
29MP0010352_gastrointestinal_tract_polyps2.13084413
30MP0003121_genomic_imprinting2.00949952
31MP0000350_abnormal_cell_proliferation2.00499630
32MP0001730_embryonic_growth_arrest1.99132374
33MP0003091_abnormal_cell_migration1.93074792
34MP0003186_abnormal_redox_activity1.91877773
35MP0003890_abnormal_embryonic-extraembry1.90995842
36MP0009697_abnormal_copulation1.80619951
37MP0003806_abnormal_nucleotide_metabolis1.79928335
38MP0000537_abnormal_urethra_morphology1.79430714
39MP0002332_abnormal_exercise_endurance1.78510511
40MP0003453_abnormal_keratinocyte_physiol1.76346797
41MP0002085_abnormal_embryonic_tissue1.74211009
42MP0003448_altered_tumor_morphology1.74051145
43MP0010368_abnormal_lymphatic_system1.71176395
44MP0002084_abnormal_developmental_patter1.69186747
45MP0006292_abnormal_olfactory_placode1.69156464
46MP0005380_embryogenesis_phenotype1.68553291
47MP0001672_abnormal_embryogenesis/_devel1.68553291
48MP0004197_abnormal_fetal_growth/weight/1.66937291
49MP0003119_abnormal_digestive_system1.66063387
50MP0001299_abnormal_eye_distance/1.65776378
51MP0001697_abnormal_embryo_size1.64650214
52MP0003315_abnormal_perineum_morphology1.62612969
53MP0001293_anophthalmia1.58382982
54MP0009053_abnormal_anal_canal1.58009677
55MP0003279_aneurysm1.57223256
56MP0005197_abnormal_uvea_morphology1.55591500
57MP0003984_embryonic_growth_retardation1.51365911
58MP0001849_ear_inflammation1.50591875
59MP0002088_abnormal_embryonic_growth/wei1.49591038
60MP0003941_abnormal_skin_development1.48712165
61MP0002254_reproductive_system_inflammat1.46709917
62MP0002249_abnormal_larynx_morphology1.42678973
63MP0009764_decreased_sensitivity_to1.39275423
64MP0002148_abnormal_hypersensitivity_rea1.38492197
65MP0005167_abnormal_blood-brain_barrier1.37022553
66MP0000049_abnormal_middle_ear1.36705355
67MP0002080_prenatal_lethality1.34254336
68MP0003937_abnormal_limbs/digits/tail_de1.32976419
69MP0000358_abnormal_cell_content/1.31955937
70MP0003567_abnormal_fetal_cardiomyocyte1.31203954
71MP0002086_abnormal_extraembryonic_tissu1.28951290
72MP0005595_abnormal_vascular_smooth1.28902322
73MP0003385_abnormal_body_wall1.28276519
74MP0003786_premature_aging1.28178346
75MP0002295_abnormal_pulmonary_circulatio1.27649724
76MP0008789_abnormal_olfactory_epithelium1.22185004
77MP0002896_abnormal_bone_mineralization1.22129287
78MP0003221_abnormal_cardiomyocyte_apopto1.20065386
79MP0003300_gastrointestinal_ulcer1.19510638
80MP0002282_abnormal_trachea_morphology1.19318156
81MP0001879_abnormal_lymphatic_vessel1.19211037
82MP0006082_CNS_inflammation1.18508804
83MP0002938_white_spotting1.16206967
84MP0010307_abnormal_tumor_latency1.15163228
85MP0002396_abnormal_hematopoietic_system1.14403782
86MP0003942_abnormal_urinary_system1.14195863
87MP0003755_abnormal_palate_morphology1.13846548
88MP0002139_abnormal_hepatobiliary_system1.11175230
89MP0004808_abnormal_hematopoietic_stem1.08677998
90MP0004272_abnormal_basement_membrane1.08122123
91MP0003656_abnormal_erythrocyte_physiolo1.07807303
92MP0002111_abnormal_tail_morphology1.07518429
93MP0003718_maternal_effect1.06697049
94MP0000313_abnormal_cell_death1.06421898
95MP0003705_abnormal_hypodermis_morpholog1.06025998
96MP0000767_abnormal_smooth_muscle1.05010503
97MP0003861_abnormal_nervous_system1.04328903
98MP0002210_abnormal_sex_determination1.03445299
99MP0000733_abnormal_muscle_development1.02102037
100MP0001243_abnormal_dermal_layer1.01604922
101MP0005193_abnormal_anterior_eye1.00322560
102MP0000647_abnormal_sebaceous_gland0.99761753
103MP0002233_abnormal_nose_morphology0.99639440
104MP0002932_abnormal_joint_morphology0.99181512
105MP0004233_abnormal_muscle_weight0.98578907
106MP0001286_abnormal_eye_development0.97335481
107MP0002751_abnormal_autonomic_nervous0.96723342
108MP0005076_abnormal_cell_differentiation0.96554934
109MP0003172_abnormal_lysosome_physiology0.95735517
110MP0005275_abnormal_skin_tensile0.95099583
111MP0000428_abnormal_craniofacial_morphol0.95090731
112MP0000432_abnormal_head_morphology0.95066294
113MP0005165_increased_susceptibility_to0.94513570
114MP0002177_abnormal_outer_ear0.94401439
115MP0000566_synostosis0.94360536
116MP0000490_abnormal_crypts_of0.93755823
117MP0003935_abnormal_craniofacial_develop0.92969424
118MP0002998_abnormal_bone_remodeling0.92902181
119MP0001915_intracranial_hemorrhage0.92678740
120MP0000750_abnormal_muscle_regeneration0.92573090
121MP0000516_abnormal_urinary_system0.91904662
122MP0005367_renal/urinary_system_phenotyp0.91904662
123MP0001145_abnormal_male_reproductive0.90386636
124MP0002102_abnormal_ear_morphology0.89869017
125MP0005248_abnormal_Harderian_gland0.89488478
126MP0004084_abnormal_cardiac_muscle0.88571664
127MP0002116_abnormal_craniofacial_bone0.87878628
128MP0001853_heart_inflammation0.87670010
129MP0002114_abnormal_axial_skeleton0.87122293
130MP0003787_abnormal_imprinting0.86875336
131MP0009384_cardiac_valve_regurgitation0.85975111
132MP0003136_yellow_coat_color0.85835345
133MP0003075_altered_response_to0.83872207
134MP0005623_abnormal_meninges_morphology0.83539673
135MP0009672_abnormal_birth_weight0.83078284
136MP0002019_abnormal_tumor_incidence0.82778299
137MP0003646_muscle_fatigue0.82210563
138MP0002092_abnormal_eye_morphology0.81681389
139MP0002127_abnormal_cardiovascular_syste0.80699982
140MP0005499_abnormal_olfactory_system0.80230051
141MP0005394_taste/olfaction_phenotype0.80230051
142MP0006072_abnormal_retinal_apoptosis0.80006024
143MP0000653_abnormal_sex_gland0.79939943
144MP0009703_decreased_birth_body0.78515054
145MP0002925_abnormal_cardiovascular_devel0.78077687
146MP0005508_abnormal_skeleton_morphology0.77727004
147MP0000534_abnormal_ureter_morphology0.77039928
148MP0002697_abnormal_eye_size0.76519863
149MP0003115_abnormal_respiratory_system0.76200960
150MP0005164_abnormal_response_to0.76082519
151MP0009250_abnormal_appendicular_skeleto0.75918522
152MP0000858_altered_metastatic_potential0.75795878
153MP0005023_abnormal_wound_healing0.75719981
154MP0005084_abnormal_gallbladder_morpholo0.75686088
155MP0000371_diluted_coat_color0.75603474
156MP0000678_abnormal_parathyroid_gland0.75536494
157MP0005384_cellular_phenotype0.69881707
158MP0002060_abnormal_skin_morphology0.67724603
159MP0001216_abnormal_epidermal_layer0.67268604
160MP0005621_abnormal_cell_physiology0.66470710
161MP0001727_abnormal_embryo_implantation0.65650543
162MP0002090_abnormal_vision0.61732331
163MP0001191_abnormal_skin_condition0.61279435
164MP0002113_abnormal_skeleton_development0.60852589
165MP0002736_abnormal_nociception_after0.59163580
166MP0000163_abnormal_cartilage_morphology0.56283047
167MP0003795_abnormal_bone_structure0.55876133

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)5.25968389
2Abnormality of glycolipid metabolism (HP:0010969)4.80056129
3Abnormality of liposaccharide metabolism (HP:0010968)4.80056129
4Abnormality of glycosphingolipid metabolism (HP:0004343)4.80056129
5Increased mean platelet volume (HP:0011877)4.53569773
6Colon cancer (HP:0003003)4.12730268
7Medulloblastoma (HP:0002885)3.85933797
8Abnormal platelet volume (HP:0011876)3.75484750
9Nuclear cataract (HP:0100018)3.70623794
10Breast hypoplasia (HP:0003187)3.70340096
11Petechiae (HP:0000967)3.60410277
12Ankle contracture (HP:0006466)3.51544918
13Ependymoma (HP:0002888)3.46490182
14Birth length less than 3rd percentile (HP:0003561)3.44206171
15Supernumerary spleens (HP:0009799)3.40480186
16Disinhibition (HP:0000734)3.36870721
17Selective tooth agenesis (HP:0001592)3.33433960
18Menorrhagia (HP:0000132)3.23349840
19Reticulocytopenia (HP:0001896)3.15709755
20Rib fusion (HP:0000902)3.05010948
21Abdominal situs inversus (HP:0003363)3.04793882
22Abnormality of abdominal situs (HP:0011620)3.04793882
23Myocardial infarction (HP:0001658)2.97110560
24Missing ribs (HP:0000921)2.95030986
25Purpura (HP:0000979)2.92421409
26Chromsome breakage (HP:0040012)2.86340559
27Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.86301421
28Short 4th metacarpal (HP:0010044)2.86301421
29Atrophic scars (HP:0001075)2.85758902
30Abnormality of the vasculature of the conjunctiva (HP:0008054)2.84054944
31Chromosomal breakage induced by crosslinking agents (HP:0003221)2.82933901
32Loss of speech (HP:0002371)2.81268366
33Tetraparesis (HP:0002273)2.81017767
34Patellar aplasia (HP:0006443)2.77623935
35Termporal pattern (HP:0011008)2.77516433
36Insidious onset (HP:0003587)2.77516433
37Vacuolated lymphocytes (HP:0001922)2.72520368
38Spinal rigidity (HP:0003306)2.72190101
39Rhabdomyosarcoma (HP:0002859)2.71989842
40Follicular hyperkeratosis (HP:0007502)2.69212684
41Apathy (HP:0000741)2.65875627
42Aplasia/Hypoplasia of the patella (HP:0006498)2.65053012
43Aplasia/hypoplasia of the humerus (HP:0006507)2.65050843
44Astrocytoma (HP:0009592)2.63489259
45Abnormality of the astrocytes (HP:0100707)2.63489259
46Absent radius (HP:0003974)2.59547790
47Abnormality of the labia minora (HP:0012880)2.58410242
48Cortical dysplasia (HP:0002539)2.57758770
49Vertebral compression fractures (HP:0002953)2.55279749
50Diminished motivation (HP:0000745)2.55055778
51Dysostosis multiplex (HP:0000943)2.53210509
52Neurofibrillary tangles (HP:0002185)2.51802949
53Upper limb muscle weakness (HP:0003484)2.50664543
54Conjunctival telangiectasia (HP:0000524)2.49652348
55Abnormality of dentin (HP:0010299)2.49326283
56Abnormal number of incisors (HP:0011064)2.47419612
57Agnosia (HP:0010524)2.47030677
58Achilles tendon contracture (HP:0001771)2.46724706
59Aplastic anemia (HP:0001915)2.46501268
60Shawl scrotum (HP:0000049)2.45690337
61Shoulder girdle muscle weakness (HP:0003547)2.44887044
62Absent forearm bone (HP:0003953)2.43831190
63Aplasia involving forearm bones (HP:0009822)2.43831190
64Supernumerary bones of the axial skeleton (HP:0009144)2.43030952
65Neoplasm of striated muscle (HP:0009728)2.41296422
66Cerebral inclusion bodies (HP:0100314)2.41031771
67Abnormality of the Achilles tendon (HP:0005109)2.39884340
68Thoracolumbar scoliosis (HP:0002944)2.37653291
69High anterior hairline (HP:0009890)2.34752246
70Neoplasm of the oral cavity (HP:0100649)2.34325688
71Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.33845125
72Short humerus (HP:0005792)2.32874312
73Glioma (HP:0009733)2.32555042
74Cervical subluxation (HP:0003308)2.27538459
75Abnormal lung lobation (HP:0002101)2.26038924
76Renal duplication (HP:0000075)2.25699495
77Atresia of the external auditory canal (HP:0000413)2.23425599
78Short nail (HP:0001799)2.22050740
79Impaired platelet aggregation (HP:0003540)2.19181120
80Abnormal platelet function (HP:0011869)2.19181120
81Meckel diverticulum (HP:0002245)2.17178416
82Supernumerary ribs (HP:0005815)2.17010809
83Inappropriate behavior (HP:0000719)2.14372567
84Entropion (HP:0000621)2.13722033
85Cleft eyelid (HP:0000625)2.12279894
86Mutism (HP:0002300)2.12112017
87Aplasia/Hypoplasia of the sacrum (HP:0008517)2.09758023
88Abnormality of the ileum (HP:0001549)2.09278222
89Absent thumb (HP:0009777)2.07561576
90Genu recurvatum (HP:0002816)2.07297138
91Proximal placement of thumb (HP:0009623)2.06704155
92Abnormality of the 4th metacarpal (HP:0010012)2.06145706
93Axonal loss (HP:0003447)2.03638821
94Vascular tortuosity (HP:0004948)2.03342063
95Facial hemangioma (HP:0000329)2.03320306
96Deviation of the thumb (HP:0009603)2.03208311
97Aplasia/Hypoplasia of the sternum (HP:0006714)2.03087959
98Spondylolisthesis (HP:0003302)2.03067620
99Oral leukoplakia (HP:0002745)2.02700300
100Carpal bone hypoplasia (HP:0001498)2.02386358
101Vertebral fusion (HP:0002948)2.00403808
102Increased nuchal translucency (HP:0010880)2.00249490
103Hemivertebrae (HP:0002937)1.99368154
10411 pairs of ribs (HP:0000878)1.99294151
105Natal tooth (HP:0000695)1.98300355
106Soft skin (HP:0000977)1.98251692
107Slender build (HP:0001533)1.98212996
108Poor head control (HP:0002421)1.96781002
109Abnormality of cells of the erythroid lineage (HP:0012130)1.96497462
110Prolonged bleeding time (HP:0003010)1.96168680
111Abnormality of the musculature of the pelvis (HP:0001469)1.95944027
112Abnormality of the hip-girdle musculature (HP:0001445)1.95944027
113Tracheoesophageal fistula (HP:0002575)1.95667459
114Embryonal renal neoplasm (HP:0011794)1.95516980
115Delayed gross motor development (HP:0002194)1.95499331
116Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.94179898
117Osteolytic defects of the hand bones (HP:0009699)1.90877860
118Osteolytic defects of the phalanges of the hand (HP:0009771)1.90877860
119Trismus (HP:0000211)1.90343468
120Prolonged neonatal jaundice (HP:0006579)1.90090037
121Abnormal trabecular bone morphology (HP:0100671)1.89490561
122Aplasia/Hypoplasia of the uvula (HP:0010293)1.89308250
123Wormian bones (HP:0002645)1.89228156
124Increased density of long bones (HP:0006392)1.89199492
125Distal upper limb amyotrophy (HP:0007149)1.88639978
126Upper limb amyotrophy (HP:0009129)1.88639978
127Stenosis of the external auditory canal (HP:0000402)1.88209322
128Adenoma sebaceum (HP:0009720)1.88074467
129Angiofibromas (HP:0010615)1.88074467
130Distal lower limb amyotrophy (HP:0008944)1.88051753
131Nephroblastoma (Wilms tumor) (HP:0002667)1.87958041
132Fused cervical vertebrae (HP:0002949)1.87562441
133Neoplasm of the pancreas (HP:0002894)1.87553773
134Metaphyseal irregularity (HP:0003025)1.87513183
135Abnormality of the umbilical cord (HP:0010881)1.87351602
136Duplicated collecting system (HP:0000081)1.85859719
137Abnormal umbilical cord blood vessels (HP:0011403)1.85658602
138Single umbilical artery (HP:0001195)1.85658602
139Abnormality of the fetal cardiovascular system (HP:0010948)1.85658602
140Protruding ear (HP:0000411)1.85423395
141Abnormality of the anterior horn cell (HP:0006802)1.85182642
142Degeneration of anterior horn cells (HP:0002398)1.85182642
143Bladder diverticulum (HP:0000015)1.84952272
144Aortic dissection (HP:0002647)1.83467675
145Upper motor neuron abnormality (HP:0002127)1.83053259
146Protrusio acetabuli (HP:0003179)1.82157306
147Arterial tortuosity (HP:0005116)1.81717911
148Limb-girdle muscle atrophy (HP:0003797)1.80633725
149Volvulus (HP:0002580)1.80066356
150Abnormality of the renal collecting system (HP:0004742)1.79784769
151Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.78836702
152Short thumb (HP:0009778)1.78740946
153Lower limb amyotrophy (HP:0007210)1.76499764
154Long toe (HP:0010511)1.73806372
155Shallow orbits (HP:0000586)1.73758238
156Ectopic kidney (HP:0000086)1.72153979
157Abnormality of mucopolysaccharide metabolism (HP:0011020)1.72035719
158Abnormality of polysaccharide metabolism (HP:0011012)1.72035719
159Abnormality of glycosaminoglycan metabolism (HP:0004371)1.72035719
160Fragile skin (HP:0001030)1.71985073
161Zonular cataract (HP:0010920)1.71818359
162Triphalangeal thumb (HP:0001199)1.71218545
163Rectovaginal fistula (HP:0000143)1.70871031
164Rectal fistula (HP:0100590)1.70871031
165Neuroblastoma (HP:0003006)1.70593915
166Primitive neuroectodermal tumor (HP:0030065)1.70593915
167Neuroblastic tumors (HP:0004376)1.70593915
168Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.70593915
169Abnormality of chromosome stability (HP:0003220)1.70308944
170Premature graying of hair (HP:0002216)1.69378064
171Myelodysplasia (HP:0002863)1.69286548
172Neoplasm of the colon (HP:0100273)1.69062308
173Pelvic girdle muscle weakness (HP:0003749)1.68770375
174Blue sclerae (HP:0000592)1.68568614
175Leiomyosarcoma (HP:0100243)1.68457647
176Uterine leiomyosarcoma (HP:0002891)1.68457647
177Glossoptosis (HP:0000162)1.68379764
178Down-sloping shoulders (HP:0200021)1.67545965
179Intestinal polyp (HP:0005266)1.67100120
180Slender long bone (HP:0003100)1.67069372
181Horseshoe kidney (HP:0000085)1.66904139
182Elbow flexion contracture (HP:0002987)1.65832513
183Rough bone trabeculation (HP:0100670)1.65256148
184Reduced subcutaneous adipose tissue (HP:0003758)1.65111541
185Pallor (HP:0000980)1.63223942
186Abnormal number of erythroid precursors (HP:0012131)1.63214037
187Cerebral hypomyelination (HP:0006808)1.62956722
188Multiple enchondromatosis (HP:0005701)1.62942532
189Hand muscle atrophy (HP:0009130)1.62251767
190Transposition of the great arteries (HP:0001669)1.61783009
191Abnormal connection of the cardiac segments (HP:0011545)1.61783009
192Abnormal ventriculo-arterial connection (HP:0011563)1.61783009
193Tibial bowing (HP:0002982)1.60712714
194Adrenal hypoplasia (HP:0000835)1.60536103
195Wrist flexion contracture (HP:0001239)1.60353688
196Limb-girdle muscle weakness (HP:0003325)1.59471659

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK195.87731515
2IRAK35.16084790
3CDC74.12981488
4BUB13.29520077
5WEE13.06982051
6MAP3K102.93891716
7ACVR1B2.80244950
8SRPK12.40624013
9PLK42.39388047
10MKNK12.37770125
11MOS2.23029936
12PDGFRA2.11140465
13LATS22.11111646
14TLK12.10816273
15CDK122.07569185
16GRK71.91316718
17DYRK31.89969729
18CDK71.89160919
19EIF2AK11.87132561
20MKNK21.86259355
21MYLK1.85116901
22PIM21.84623939
23TGFBR21.76215257
24TTK1.74761119
25PTK21.69900686
26EPHB21.68536437
27PLK11.63123081
28TRIM281.59763700
29TESK21.58149490
30TNIK1.53594832
31NEK11.50152058
32BMX1.47498816
33RPS6KB21.46447196
34PAK41.45936036
35CHEK21.45081471
36STK38L1.44793209
37ATR1.41618696
38PLK31.37493950
39NEK21.35771503
40RPS6KA41.32861416
41TGFBR11.30981751
42BRSK21.30623367
43LATS11.29982068
44CDK41.25939149
45AURKB1.21649813
46ADRBK21.21588175
47TAOK11.20829027
48PAK21.20138989
49MST41.15590342
50MAP3K31.14549446
51STK41.12247330
52LIMK11.11042497
53AURKA1.08335905
54VRK11.07484428
55FGR1.05276656
56EPHA21.04516112
57MAP2K31.03400350
58ARAF1.02371668
59TESK11.02150003
60MAP3K61.02087723
61MAP3K81.01243397
62CDK60.98945228
63CHEK10.98005756
64ERBB30.96941907
65SIK30.94447324
66DYRK20.91702399
67TSSK60.91670924
68MAP3K120.90519749
69PASK0.90333390
70NTRK10.90097935
71MAP2K70.85330098
72SCYL20.83166502
73CDK20.80199233
74ATM0.78784896
75NME20.77402489
76MST1R0.77200835
77TTN0.76836340
78BRSK10.76176359
79STK100.75580135
80MATK0.72896458
81TIE10.72487824
82CDK11A0.72304266
83ILK0.71276025
84FLT30.69861103
85CDK90.69502803
86PNCK0.68085888
87EIF2AK30.66402975
88IRAK20.64147020
89CLK10.63688624
90GSK3A0.62630954
91CDK80.62534589
92KSR10.62287400
93CSNK1G20.61667001
94PAK10.61344914
95PDGFRB0.59003129
96BCR0.58868117
97ROCK20.57894295
98CDK10.56846440
99BRD40.56651676
100MET0.55950846
101PAK60.55926365
102PKN20.55372120
103DDR20.53703629
104LMTK20.53154771
105ALK0.53030343
106ZAK0.52173027
107CSNK2A20.51844837
108ABL20.51509414
109MAPKAPK30.50902447
110PBK0.50028148
111TAOK20.49857235
112MTOR0.49698783
113LRRK20.49387770
114STK240.49301190
115ERBB40.48564997
116CSNK1G10.47911961
117CSNK2A10.47880035
118PLK20.46140076
119AKT20.46002730
120STK160.45955817
121PRKG20.45666843
122DMPK0.45078377
123MAP3K90.44153622
124MAP3K40.43384363
125ROCK10.41703006
126TYRO30.41469958
127CDK140.40730496
128CDK180.40459191
129BRAF0.39713446
130CDK150.39001278
131MELK0.38770072
132CSNK1E0.38498248
133PIM10.38458752
134DAPK10.37231288
135FGFR10.35198945
136PRKDC0.35167179
137DAPK30.33685074
138STK30.32652919
139CSNK1G30.32388371
140MAP3K50.31388450
141EIF2AK20.31353495
142PRKCI0.31197654
143OBSCN0.31118816
144EEF2K0.30559271

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.90119351
2Mismatch repair_Homo sapiens_hsa034304.36228640
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.37114284
4Spliceosome_Homo sapiens_hsa030403.37011722
5Ribosome_Homo sapiens_hsa030103.24513364
6RNA transport_Homo sapiens_hsa030133.23926696
7Cell cycle_Homo sapiens_hsa041102.99588968
8RNA polymerase_Homo sapiens_hsa030202.94797012
9Base excision repair_Homo sapiens_hsa034102.81329356
10Nucleotide excision repair_Homo sapiens_hsa034202.68728411
11Homologous recombination_Homo sapiens_hsa034402.64730403
12Proteasome_Homo sapiens_hsa030502.49700923
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.31262976
14Salmonella infection_Homo sapiens_hsa051322.30365658
15Lysosome_Homo sapiens_hsa041422.22265780
16mRNA surveillance pathway_Homo sapiens_hsa030152.17334500
17Pyrimidine metabolism_Homo sapiens_hsa002402.11854884
18Glycosaminoglycan degradation_Homo sapiens_hsa005312.08384088
19RNA degradation_Homo sapiens_hsa030182.06973800
20Non-homologous end-joining_Homo sapiens_hsa034502.02117024
21One carbon pool by folate_Homo sapiens_hsa006702.01770535
22Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.00727127
23Steroid biosynthesis_Homo sapiens_hsa001002.00246504
24Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.89092803
25Vibrio cholerae infection_Homo sapiens_hsa051101.85670322
26Basal transcription factors_Homo sapiens_hsa030221.80906171
27Fanconi anemia pathway_Homo sapiens_hsa034601.80483474
28Sulfur metabolism_Homo sapiens_hsa009201.76834404
29Malaria_Homo sapiens_hsa051441.68122705
30Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.64028721
31Rheumatoid arthritis_Homo sapiens_hsa053231.63582197
32p53 signaling pathway_Homo sapiens_hsa041151.56502902
33TNF signaling pathway_Homo sapiens_hsa046681.56166892
34Other glycan degradation_Homo sapiens_hsa005111.54665505
35Toll-like receptor signaling pathway_Homo sapiens_hsa046201.44587503
36Collecting duct acid secretion_Homo sapiens_hsa049661.35136498
37Oocyte meiosis_Homo sapiens_hsa041141.32862954
38Amoebiasis_Homo sapiens_hsa051461.31403004
39Sphingolipid metabolism_Homo sapiens_hsa006001.30258527
40Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.29362371
41Basal cell carcinoma_Homo sapiens_hsa052171.28747246
42Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.28207247
43Pertussis_Homo sapiens_hsa051331.25639276
44Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.24647057
45Fatty acid elongation_Homo sapiens_hsa000621.24470742
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.23590409
47Hippo signaling pathway_Homo sapiens_hsa043901.19980183
48NOD-like receptor signaling pathway_Homo sapiens_hsa046211.17850488
49Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.15084503
50Prion diseases_Homo sapiens_hsa050201.11335240
51TGF-beta signaling pathway_Homo sapiens_hsa043501.10895189
52Purine metabolism_Homo sapiens_hsa002301.10582123
53MicroRNAs in cancer_Homo sapiens_hsa052061.10399035
54Phagosome_Homo sapiens_hsa041451.06368767
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.05906070
56Epstein-Barr virus infection_Homo sapiens_hsa051691.04091289
57Hedgehog signaling pathway_Homo sapiens_hsa043401.02936539
58Systemic lupus erythematosus_Homo sapiens_hsa053221.02922734
59Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.02487970
60Folate biosynthesis_Homo sapiens_hsa007901.02231204
61SNARE interactions in vesicular transport_Homo sapiens_hsa041300.95801150
62RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.93314647
63HTLV-I infection_Homo sapiens_hsa051660.91622410
64Huntingtons disease_Homo sapiens_hsa050160.90697103
65Gap junction_Homo sapiens_hsa045400.89395772
66Platelet activation_Homo sapiens_hsa046110.87846394
67Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.87615614
68Viral carcinogenesis_Homo sapiens_hsa052030.87381032
69Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.85726074
70NF-kappa B signaling pathway_Homo sapiens_hsa040640.82959068
71Thyroid cancer_Homo sapiens_hsa052160.80982128
72Colorectal cancer_Homo sapiens_hsa052100.80044222
73Renin-angiotensin system_Homo sapiens_hsa046140.78988517
74Small cell lung cancer_Homo sapiens_hsa052220.73911932
75Renal cell carcinoma_Homo sapiens_hsa052110.73721092
76Bladder cancer_Homo sapiens_hsa052190.71902321
77Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.71449689
78Notch signaling pathway_Homo sapiens_hsa043300.70260484
79Biosynthesis of amino acids_Homo sapiens_hsa012300.69786784
80Synaptic vesicle cycle_Homo sapiens_hsa047210.69050775
81Wnt signaling pathway_Homo sapiens_hsa043100.66348380
82Adherens junction_Homo sapiens_hsa045200.65677105
83Parkinsons disease_Homo sapiens_hsa050120.65619461
84Endocytosis_Homo sapiens_hsa041440.65497001
85Herpes simplex infection_Homo sapiens_hsa051680.64554377
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64161901
87Tight junction_Homo sapiens_hsa045300.63451666
88Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60790878
89Cysteine and methionine metabolism_Homo sapiens_hsa002700.60039928
90Osteoclast differentiation_Homo sapiens_hsa043800.59221244
91Melanoma_Homo sapiens_hsa052180.59121194
92Central carbon metabolism in cancer_Homo sapiens_hsa052300.58954223
93Alcoholism_Homo sapiens_hsa050340.57622118
94Pathways in cancer_Homo sapiens_hsa052000.57563253
95Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57056706
96Pentose phosphate pathway_Homo sapiens_hsa000300.55736136
97Cardiac muscle contraction_Homo sapiens_hsa042600.52612067
98Selenocompound metabolism_Homo sapiens_hsa004500.51530305
99HIF-1 signaling pathway_Homo sapiens_hsa040660.51192414
100Rap1 signaling pathway_Homo sapiens_hsa040150.50857479
1012-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.49763747
102Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.49164242
103Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.49135764
104N-Glycan biosynthesis_Homo sapiens_hsa005100.48650026
105Shigellosis_Homo sapiens_hsa051310.47365513
106Chronic myeloid leukemia_Homo sapiens_hsa052200.46476001
107Sulfur relay system_Homo sapiens_hsa041220.46043897
108Viral myocarditis_Homo sapiens_hsa054160.43744964
109Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.42495663
110Proteoglycans in cancer_Homo sapiens_hsa052050.41107729
111mTOR signaling pathway_Homo sapiens_hsa041500.40009505
112Primary bile acid biosynthesis_Homo sapiens_hsa001200.39846212
113Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.39614137
114Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.39438822
115Glutathione metabolism_Homo sapiens_hsa004800.39382031
116Legionellosis_Homo sapiens_hsa051340.38291547
117Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.38120817
118Oxidative phosphorylation_Homo sapiens_hsa001900.36707589
119Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.35893212
120Ras signaling pathway_Homo sapiens_hsa040140.35143968
121Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.35084797
122Axon guidance_Homo sapiens_hsa043600.34564384
123African trypanosomiasis_Homo sapiens_hsa051430.34012271
124Focal adhesion_Homo sapiens_hsa045100.33728118
125Carbon metabolism_Homo sapiens_hsa012000.31367204
126Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31133499
127PI3K-Akt signaling pathway_Homo sapiens_hsa041510.30110759
128Hepatitis B_Homo sapiens_hsa051610.27100531
129Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.26358972
130Endometrial cancer_Homo sapiens_hsa052130.26274913
131Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.24881716
132ECM-receptor interaction_Homo sapiens_hsa045120.23920305
133Neurotrophin signaling pathway_Homo sapiens_hsa047220.23686397
134Apoptosis_Homo sapiens_hsa042100.21872504
135Dilated cardiomyopathy_Homo sapiens_hsa054140.21865192
136Galactose metabolism_Homo sapiens_hsa000520.21641990
137Non-small cell lung cancer_Homo sapiens_hsa052230.21562932
138Prostate cancer_Homo sapiens_hsa052150.21388867
139Regulation of actin cytoskeleton_Homo sapiens_hsa048100.20443201
140AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.20142342
141Protein export_Homo sapiens_hsa030600.19601906
142Thyroid hormone signaling pathway_Homo sapiens_hsa049190.19171193
143Pancreatic cancer_Homo sapiens_hsa052120.18564938
144FoxO signaling pathway_Homo sapiens_hsa040680.17377313
145Glioma_Homo sapiens_hsa052140.16336178
146VEGF signaling pathway_Homo sapiens_hsa043700.16045440
147Melanogenesis_Homo sapiens_hsa049160.16011973

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »