

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | establishment of integrated proviral latency (GO:0075713) | 4.86442436 |
| 2 | CENP-A containing nucleosome assembly (GO:0034080) | 4.33858490 |
| 3 | formation of translation preinitiation complex (GO:0001731) | 4.32251783 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 4.27424691 |
| 5 | chromatin remodeling at centromere (GO:0031055) | 4.27317720 |
| 6 | ribosomal large subunit biogenesis (GO:0042273) | 4.14712349 |
| 7 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.93374187 |
| 8 | rRNA modification (GO:0000154) | 3.86017791 |
| 9 | ribosomal small subunit biogenesis (GO:0042274) | 3.82406102 |
| 10 | mitotic metaphase plate congression (GO:0007080) | 3.82260302 |
| 11 | proteasome assembly (GO:0043248) | 3.80874927 |
| 12 | DNA replication checkpoint (GO:0000076) | 3.80235037 |
| 13 | regulation of mitochondrial translation (GO:0070129) | 3.79017857 |
| 14 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.78446974 |
| 15 | establishment of viral latency (GO:0019043) | 3.76254093 |
| 16 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.74688628 |
| 17 | histone exchange (GO:0043486) | 3.72028880 |
| 18 | purine nucleobase biosynthetic process (GO:0009113) | 3.69839129 |
| 19 | translational termination (GO:0006415) | 3.68942619 |
| 20 | viral transcription (GO:0019083) | 3.66319897 |
| 21 | DNA strand elongation (GO:0022616) | 3.65791367 |
| 22 | chaperone-mediated protein transport (GO:0072321) | 3.59693100 |
| 23 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.57390381 |
| 24 | rRNA methylation (GO:0031167) | 3.54795641 |
| 25 | telomere maintenance via recombination (GO:0000722) | 3.53888100 |
| 26 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.52955816 |
| 27 | mitotic recombination (GO:0006312) | 3.52702974 |
| 28 | metaphase plate congression (GO:0051310) | 3.52484686 |
| 29 | translational initiation (GO:0006413) | 3.52447643 |
| 30 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.51597452 |
| 31 | cotranslational protein targeting to membrane (GO:0006613) | 3.47675518 |
| 32 | maturation of SSU-rRNA (GO:0030490) | 3.47629775 |
| 33 | kinetochore organization (GO:0051383) | 3.46681861 |
| 34 | ribosome assembly (GO:0042255) | 3.45203891 |
| 35 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.44368114 |
| 36 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.41269491 |
| 37 | DNA replication-independent nucleosome organization (GO:0034724) | 3.41269491 |
| 38 | protein targeting to ER (GO:0045047) | 3.41218122 |
| 39 | nucleobase biosynthetic process (GO:0046112) | 3.38019028 |
| 40 | IMP biosynthetic process (GO:0006188) | 3.36471560 |
| 41 | ribosome biogenesis (GO:0042254) | 3.35944430 |
| 42 | protein localization to kinetochore (GO:0034501) | 3.35573435 |
| 43 | DNA unwinding involved in DNA replication (GO:0006268) | 3.34659917 |
| 44 | resolution of meiotic recombination intermediates (GO:0000712) | 3.33301811 |
| 45 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.32498888 |
| 46 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.31255201 |
| 47 | translational elongation (GO:0006414) | 3.27888229 |
| 48 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.27562984 |
| 49 | protein localization to endoplasmic reticulum (GO:0070972) | 3.25528191 |
| 50 | kinetochore assembly (GO:0051382) | 3.24141075 |
| 51 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.23517827 |
| 52 | mitotic chromosome condensation (GO:0007076) | 3.22600918 |
| 53 | mitotic sister chromatid segregation (GO:0000070) | 3.22111108 |
| 54 | protein localization to chromosome, centromeric region (GO:0071459) | 3.21335753 |
| 55 | cullin deneddylation (GO:0010388) | 3.20522488 |
| 56 | translation (GO:0006412) | 3.19399314 |
| 57 | mitotic sister chromatid cohesion (GO:0007064) | 3.18916600 |
| 58 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.18148610 |
| 59 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.14169017 |
| 60 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.12918390 |
| 61 | tRNA aminoacylation for protein translation (GO:0006418) | 3.10634147 |
| 62 | protein K6-linked ubiquitination (GO:0085020) | 3.06680776 |
| 63 | transcription from mitochondrial promoter (GO:0006390) | 3.05997753 |
| 64 | cellular component biogenesis (GO:0044085) | 3.04935751 |
| 65 | negative regulation of ligase activity (GO:0051352) | 3.02456019 |
| 66 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.02456019 |
| 67 | amino acid activation (GO:0043038) | 3.01826418 |
| 68 | tRNA aminoacylation (GO:0043039) | 3.01826418 |
| 69 | viral life cycle (GO:0019058) | 3.01416679 |
| 70 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.00832022 |
| 71 | ATP synthesis coupled proton transport (GO:0015986) | 3.00832022 |
| 72 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.00337209 |
| 73 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.99337793 |
| 74 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.99337793 |
| 75 | sister chromatid segregation (GO:0000819) | 2.98413616 |
| 76 | rRNA processing (GO:0006364) | 2.96531876 |
| 77 | protein deneddylation (GO:0000338) | 2.95473318 |
| 78 | regulation of chromosome segregation (GO:0051983) | 2.95273562 |
| 79 | mitotic spindle checkpoint (GO:0071174) | 2.94756976 |
| 80 | spindle checkpoint (GO:0031577) | 2.93971467 |
| 81 | cellular protein complex disassembly (GO:0043624) | 2.92407802 |
| 82 | regulation of centriole replication (GO:0046599) | 2.92034474 |
| 83 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.91045291 |
| 84 | nuclear pore complex assembly (GO:0051292) | 2.90686365 |
| 85 | DNA damage response, detection of DNA damage (GO:0042769) | 2.90639436 |
| 86 | spliceosomal snRNP assembly (GO:0000387) | 2.90079220 |
| 87 | mitotic nuclear envelope disassembly (GO:0007077) | 2.89558279 |
| 88 | synapsis (GO:0007129) | 2.88392816 |
| 89 | protein targeting to mitochondrion (GO:0006626) | 2.87456098 |
| 90 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.86529690 |
| 91 | telomere maintenance via telomere lengthening (GO:0010833) | 2.86279221 |
| 92 | 7-methylguanosine mRNA capping (GO:0006370) | 2.86204931 |
| 93 | regulation of meiosis I (GO:0060631) | 2.85884390 |
| 94 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.85583268 |
| 95 | negative regulation of sister chromatid segregation (GO:0033046) | 2.85583268 |
| 96 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.85583268 |
| 97 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.85583268 |
| 98 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.85583268 |
| 99 | IMP metabolic process (GO:0046040) | 2.85075495 |
| 100 | negative regulation of chromosome segregation (GO:0051985) | 2.83929162 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.75323313 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.71563834 |
| 3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.11722322 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.06396368 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.64975720 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.60878987 |
| 7 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.50126945 |
| 8 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.39474481 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.35467606 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.20978800 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.97697655 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.95405280 |
| 13 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.92919090 |
| 14 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.90894741 |
| 15 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.83191431 |
| 16 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.79493045 |
| 17 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.79167264 |
| 18 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.76143292 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.74892439 |
| 20 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.63515536 |
| 21 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.61666569 |
| 22 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.60340802 |
| 23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.46119539 |
| 24 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.45497718 |
| 25 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.41604913 |
| 26 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.39814606 |
| 27 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.33298803 |
| 28 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.28264094 |
| 29 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.24673896 |
| 30 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.24049947 |
| 31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.23367129 |
| 32 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.21179178 |
| 33 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.20770354 |
| 34 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.12261342 |
| 35 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.08867740 |
| 36 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.97285424 |
| 37 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.95825323 |
| 38 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.94659218 |
| 39 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.93749960 |
| 40 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.92665984 |
| 41 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.92368557 |
| 42 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.86286682 |
| 43 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.86197284 |
| 44 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.83071869 |
| 45 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.73967657 |
| 46 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.70720167 |
| 47 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.66730157 |
| 48 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.63154965 |
| 49 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.62775832 |
| 50 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.53348345 |
| 51 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.53309731 |
| 52 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.36840115 |
| 53 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.35108495 |
| 54 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.34119919 |
| 55 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.30184915 |
| 56 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.28402661 |
| 57 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.27122867 |
| 58 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.25001183 |
| 59 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.20376792 |
| 60 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.20214579 |
| 61 | VDR_22108803_ChIP-Seq_LS180_Human | 1.20196373 |
| 62 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.19640221 |
| 63 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.16393560 |
| 64 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.15882706 |
| 65 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.15357640 |
| 66 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.14531061 |
| 67 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.14405366 |
| 68 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.13755368 |
| 69 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.11503552 |
| 70 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.07807876 |
| 71 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.07134664 |
| 72 | EWS_26573619_Chip-Seq_HEK293_Human | 1.05911142 |
| 73 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.05773008 |
| 74 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.05773008 |
| 75 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.05773008 |
| 76 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.00533492 |
| 77 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.00176400 |
| 78 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.00080130 |
| 79 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95399656 |
| 80 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.95337499 |
| 81 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.94944507 |
| 82 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.94087666 |
| 83 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.92672920 |
| 84 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.90857392 |
| 85 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.89571675 |
| 86 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.89135641 |
| 87 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.87150765 |
| 88 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.84580915 |
| 89 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.81480534 |
| 90 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.80729970 |
| 91 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.80168069 |
| 92 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.80160219 |
| 93 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.79093072 |
| 94 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.78366090 |
| 95 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.78140811 |
| 96 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.76014929 |
| 97 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.75812687 |
| 98 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.72836202 |
| 99 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.70578968 |
| 100 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.70525572 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 4.83401894 |
| 2 | MP0008058_abnormal_DNA_repair | 4.29952303 |
| 3 | MP0004957_abnormal_blastocyst_morpholog | 4.20683379 |
| 4 | MP0010094_abnormal_chromosome_stability | 4.04567858 |
| 5 | MP0003077_abnormal_cell_cycle | 3.23300541 |
| 6 | MP0003111_abnormal_nucleus_morphology | 3.16058010 |
| 7 | MP0008932_abnormal_embryonic_tissue | 2.83399195 |
| 8 | MP0009697_abnormal_copulation | 2.66936088 |
| 9 | MP0010030_abnormal_orbit_morphology | 2.44051532 |
| 10 | MP0003718_maternal_effect | 2.39736726 |
| 11 | MP0006292_abnormal_olfactory_placode | 2.27575725 |
| 12 | MP0008007_abnormal_cellular_replicative | 2.25080802 |
| 13 | MP0003941_abnormal_skin_development | 2.22586493 |
| 14 | MP0008057_abnormal_DNA_replication | 2.21400923 |
| 15 | MP0003786_premature_aging | 2.10607086 |
| 16 | MP0001293_anophthalmia | 2.06896201 |
| 17 | MP0006035_abnormal_mitochondrial_morpho | 2.03227319 |
| 18 | MP0002938_white_spotting | 1.99299608 |
| 19 | MP0009379_abnormal_foot_pigmentation | 1.84174317 |
| 20 | MP0001730_embryonic_growth_arrest | 1.78954378 |
| 21 | MP0003186_abnormal_redox_activity | 1.70249647 |
| 22 | MP0002210_abnormal_sex_determination | 1.68879763 |
| 23 | MP0000350_abnormal_cell_proliferation | 1.64217158 |
| 24 | MP0001697_abnormal_embryo_size | 1.63087376 |
| 25 | MP0003890_abnormal_embryonic-extraembry | 1.61831297 |
| 26 | MP0008877_abnormal_DNA_methylation | 1.55096603 |
| 27 | MP0005380_embryogenesis_phenotype | 1.51509579 |
| 28 | MP0001672_abnormal_embryogenesis/_devel | 1.51509579 |
| 29 | MP0003315_abnormal_perineum_morphology | 1.51019823 |
| 30 | MP0000358_abnormal_cell_content/ | 1.47935992 |
| 31 | MP0001929_abnormal_gametogenesis | 1.47389357 |
| 32 | MP0002085_abnormal_embryonic_tissue | 1.47120475 |
| 33 | MP0008789_abnormal_olfactory_epithelium | 1.42200650 |
| 34 | MP0000647_abnormal_sebaceous_gland | 1.41433451 |
| 35 | MP0002084_abnormal_developmental_patter | 1.41422464 |
| 36 | MP0003937_abnormal_limbs/digits/tail_de | 1.41244092 |
| 37 | MP0008995_early_reproductive_senescence | 1.41060939 |
| 38 | MP0002080_prenatal_lethality | 1.38578100 |
| 39 | MP0005075_abnormal_melanosome_morpholog | 1.38236557 |
| 40 | MP0003136_yellow_coat_color | 1.35986919 |
| 41 | MP0003123_paternal_imprinting | 1.35010658 |
| 42 | MP0006036_abnormal_mitochondrial_physio | 1.31092405 |
| 43 | MP0001145_abnormal_male_reproductive | 1.30983834 |
| 44 | MP0003984_embryonic_growth_retardation | 1.29877359 |
| 45 | MP0000372_irregular_coat_pigmentation | 1.29815829 |
| 46 | MP0002088_abnormal_embryonic_growth/wei | 1.29223029 |
| 47 | MP0001286_abnormal_eye_development | 1.28879823 |
| 48 | MP0000653_abnormal_sex_gland | 1.25059407 |
| 49 | MP0000313_abnormal_cell_death | 1.16181253 |
| 50 | MP0009672_abnormal_birth_weight | 1.15949266 |
| 51 | MP0001529_abnormal_vocalization | 1.15925423 |
| 52 | MP0000566_synostosis | 1.13849876 |
| 53 | MP0002697_abnormal_eye_size | 1.12798430 |
| 54 | MP0002796_impaired_skin_barrier | 1.08668400 |
| 55 | MP0002234_abnormal_pharynx_morphology | 1.07834431 |
| 56 | MP0002233_abnormal_nose_morphology | 1.06317916 |
| 57 | MP0003698_abnormal_male_reproductive | 1.05304869 |
| 58 | MP0003806_abnormal_nucleotide_metabolis | 1.04349000 |
| 59 | MP0004197_abnormal_fetal_growth/weight/ | 1.01162987 |
| 60 | MP0005501_abnormal_skin_physiology | 1.00838261 |
| 61 | MP0002111_abnormal_tail_morphology | 1.00164365 |
| 62 | MP0005394_taste/olfaction_phenotype | 0.97980074 |
| 63 | MP0005499_abnormal_olfactory_system | 0.97980074 |
| 64 | MP0003119_abnormal_digestive_system | 0.95694857 |
| 65 | MP0003567_abnormal_fetal_cardiomyocyte | 0.95680537 |
| 66 | MP0000537_abnormal_urethra_morphology | 0.93662206 |
| 67 | MP0005410_abnormal_fertilization | 0.93584890 |
| 68 | MP0001119_abnormal_female_reproductive | 0.93366064 |
| 69 | MP0008260_abnormal_autophagy | 0.91451362 |
| 70 | MP0000579_abnormal_nail_morphology | 0.89444980 |
| 71 | MP0003936_abnormal_reproductive_system | 0.85359013 |
| 72 | MP0009703_decreased_birth_body | 0.85193979 |
| 73 | MP0002086_abnormal_extraembryonic_tissu | 0.85091843 |
| 74 | MP0002160_abnormal_reproductive_system | 0.83870651 |
| 75 | MP0006072_abnormal_retinal_apoptosis | 0.83704007 |
| 76 | MP0005367_renal/urinary_system_phenotyp | 0.83450890 |
| 77 | MP0000516_abnormal_urinary_system | 0.83450890 |
| 78 | MP0003755_abnormal_palate_morphology | 0.77684448 |
| 79 | MP0002161_abnormal_fertility/fecundity | 0.77586184 |
| 80 | MP0001727_abnormal_embryo_implantation | 0.77304055 |
| 81 | MP0005408_hypopigmentation | 0.76601693 |
| 82 | MP0000049_abnormal_middle_ear | 0.75465221 |
| 83 | MP0003942_abnormal_urinary_system | 0.73740182 |
| 84 | MP0002751_abnormal_autonomic_nervous | 0.72624389 |
| 85 | MP0010307_abnormal_tumor_latency | 0.72453269 |
| 86 | MP0005084_abnormal_gallbladder_morpholo | 0.71236559 |
| 87 | MP0003699_abnormal_female_reproductive | 0.71214345 |
| 88 | MP0009053_abnormal_anal_canal | 0.71058665 |
| 89 | MP0002736_abnormal_nociception_after | 0.70759825 |
| 90 | MP0003943_abnormal_hepatobiliary_system | 0.69768936 |
| 91 | MP0003861_abnormal_nervous_system | 0.69768679 |
| 92 | MP0001340_abnormal_eyelid_morphology | 0.69255102 |
| 93 | MP0003935_abnormal_craniofacial_develop | 0.67976974 |
| 94 | MP0001661_extended_life_span | 0.66210978 |
| 95 | MP0010352_gastrointestinal_tract_polyps | 0.65026096 |
| 96 | MP0005395_other_phenotype | 0.63133622 |
| 97 | MP0002177_abnormal_outer_ear | 0.62965219 |
| 98 | MP0001881_abnormal_mammary_gland | 0.62335913 |
| 99 | MP0000627_abnormal_mammary_gland | 0.62171615 |
| 100 | MP0002092_abnormal_eye_morphology | 0.62124276 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.21433113 |
| 2 | Chromsome breakage (HP:0040012) | 3.99188760 |
| 3 | Reticulocytopenia (HP:0001896) | 3.97320770 |
| 4 | Increased hepatocellular lipid droplets (HP:0006565) | 3.64738525 |
| 5 | Abnormality of the preputium (HP:0100587) | 3.41930774 |
| 6 | Meckel diverticulum (HP:0002245) | 3.36691762 |
| 7 | Lipid accumulation in hepatocytes (HP:0006561) | 3.32978291 |
| 8 | Acute necrotizing encephalopathy (HP:0006965) | 3.31186837 |
| 9 | Acute encephalopathy (HP:0006846) | 3.30447675 |
| 10 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.23982102 |
| 11 | Abnormality of the ileum (HP:0001549) | 3.15081170 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.10215386 |
| 13 | Abnormality of chromosome stability (HP:0003220) | 3.05001631 |
| 14 | Increased CSF lactate (HP:0002490) | 2.87612002 |
| 15 | Mitochondrial inheritance (HP:0001427) | 2.85793534 |
| 16 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.84023471 |
| 17 | Small intestinal stenosis (HP:0012848) | 2.83840954 |
| 18 | Duodenal stenosis (HP:0100867) | 2.83840954 |
| 19 | Macrocytic anemia (HP:0001972) | 2.80842153 |
| 20 | Abnormal number of erythroid precursors (HP:0012131) | 2.73471314 |
| 21 | Absent thumb (HP:0009777) | 2.72957687 |
| 22 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.70828418 |
| 23 | Degeneration of anterior horn cells (HP:0002398) | 2.69957497 |
| 24 | Abnormality of the anterior horn cell (HP:0006802) | 2.69957497 |
| 25 | Abnormal lung lobation (HP:0002101) | 2.67626452 |
| 26 | Renal Fanconi syndrome (HP:0001994) | 2.65784216 |
| 27 | Microvesicular hepatic steatosis (HP:0001414) | 2.64615491 |
| 28 | Hepatocellular necrosis (HP:0001404) | 2.62168429 |
| 29 | Cerebral edema (HP:0002181) | 2.59487249 |
| 30 | Progressive macrocephaly (HP:0004481) | 2.55088275 |
| 31 | Abnormality of the labia minora (HP:0012880) | 2.44383483 |
| 32 | Horseshoe kidney (HP:0000085) | 2.38872991 |
| 33 | Abnormality of the duodenum (HP:0002246) | 2.35627403 |
| 34 | Abnormality of methionine metabolism (HP:0010901) | 2.34933088 |
| 35 | Triphalangeal thumb (HP:0001199) | 2.32899652 |
| 36 | Reduced antithrombin III activity (HP:0001976) | 2.31048188 |
| 37 | Type I transferrin isoform profile (HP:0003642) | 2.29959824 |
| 38 | Microglossia (HP:0000171) | 2.28957341 |
| 39 | Hepatic necrosis (HP:0002605) | 2.28305462 |
| 40 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.28260633 |
| 41 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.28260633 |
| 42 | Increased serum lactate (HP:0002151) | 2.26772042 |
| 43 | Myelodysplasia (HP:0002863) | 2.24954993 |
| 44 | Pallor (HP:0000980) | 2.19381147 |
| 45 | Sparse eyelashes (HP:0000653) | 2.16937374 |
| 46 | Increased intramyocellular lipid droplets (HP:0012240) | 2.16656392 |
| 47 | Lactic acidosis (HP:0003128) | 2.14794984 |
| 48 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.14559430 |
| 49 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.14559430 |
| 50 | Abnormal protein glycosylation (HP:0012346) | 2.14559430 |
| 51 | Abnormal glycosylation (HP:0012345) | 2.14559430 |
| 52 | Abnormality of the carotid arteries (HP:0005344) | 2.14455268 |
| 53 | Birth length less than 3rd percentile (HP:0003561) | 2.13852927 |
| 54 | Aplastic anemia (HP:0001915) | 2.09398069 |
| 55 | Cortical dysplasia (HP:0002539) | 2.02949878 |
| 56 | Sclerocornea (HP:0000647) | 2.01752553 |
| 57 | Hyperglycinemia (HP:0002154) | 2.00612451 |
| 58 | Abnormal hair whorl (HP:0010721) | 1.97861419 |
| 59 | Multiple enchondromatosis (HP:0005701) | 1.96668183 |
| 60 | Exercise intolerance (HP:0003546) | 1.96603923 |
| 61 | Volvulus (HP:0002580) | 1.94708285 |
| 62 | Sloping forehead (HP:0000340) | 1.93231506 |
| 63 | Abnormality of serum amino acid levels (HP:0003112) | 1.87526888 |
| 64 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.86809963 |
| 65 | Colon cancer (HP:0003003) | 1.86225840 |
| 66 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.85565931 |
| 67 | Abnormality of renal resorption (HP:0011038) | 1.85348361 |
| 68 | Respiratory difficulties (HP:0002880) | 1.85289082 |
| 69 | Exertional dyspnea (HP:0002875) | 1.84360901 |
| 70 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.84096842 |
| 71 | 3-Methylglutaconic aciduria (HP:0003535) | 1.82608166 |
| 72 | Septate vagina (HP:0001153) | 1.82456071 |
| 73 | Pancreatic fibrosis (HP:0100732) | 1.82327368 |
| 74 | Short tibia (HP:0005736) | 1.80030079 |
| 75 | Increased serum pyruvate (HP:0003542) | 1.79853127 |
| 76 | Testicular atrophy (HP:0000029) | 1.77073000 |
| 77 | Choanal atresia (HP:0000453) | 1.75058313 |
| 78 | Abnormality of reticulocytes (HP:0004312) | 1.73247418 |
| 79 | Increased nuchal translucency (HP:0010880) | 1.72895243 |
| 80 | Facial cleft (HP:0002006) | 1.72636956 |
| 81 | Abnormality of glycolysis (HP:0004366) | 1.72198774 |
| 82 | Absent radius (HP:0003974) | 1.71876225 |
| 83 | Pancytopenia (HP:0001876) | 1.71558559 |
| 84 | Median cleft lip (HP:0000161) | 1.70969994 |
| 85 | Embryonal renal neoplasm (HP:0011794) | 1.70775937 |
| 86 | Concave nail (HP:0001598) | 1.69359037 |
| 87 | Respiratory failure (HP:0002878) | 1.69306235 |
| 88 | Clubbing of toes (HP:0100760) | 1.69179618 |
| 89 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.68742926 |
| 90 | Hyperglycinuria (HP:0003108) | 1.68148961 |
| 91 | Increased muscle lipid content (HP:0009058) | 1.67988787 |
| 92 | Abnormal spermatogenesis (HP:0008669) | 1.66905523 |
| 93 | Stenosis of the external auditory canal (HP:0000402) | 1.66203042 |
| 94 | CNS hypomyelination (HP:0003429) | 1.66097851 |
| 95 | Cerebral hypomyelination (HP:0006808) | 1.65821634 |
| 96 | Abnormality of DNA repair (HP:0003254) | 1.65182195 |
| 97 | Postnatal microcephaly (HP:0005484) | 1.62191049 |
| 98 | Preaxial hand polydactyly (HP:0001177) | 1.61992903 |
| 99 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.61806031 |
| 100 | Abnormality of homocysteine metabolism (HP:0010919) | 1.61335255 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 4.45971249 |
| 2 | PBK | 3.67769458 |
| 3 | VRK2 | 3.29246152 |
| 4 | SRPK1 | 3.05350951 |
| 5 | TTK | 3.04971887 |
| 6 | CDC7 | 2.85766837 |
| 7 | NEK1 | 2.70751676 |
| 8 | PLK4 | 2.70365077 |
| 9 | MST4 | 2.70102374 |
| 10 | STK16 | 2.69317366 |
| 11 | BRSK2 | 2.54203859 |
| 12 | NME1 | 2.47396341 |
| 13 | EIF2AK1 | 2.37557643 |
| 14 | WEE1 | 2.29024841 |
| 15 | ZAK | 2.12883621 |
| 16 | TRIM28 | 2.07035686 |
| 17 | TSSK6 | 1.93595517 |
| 18 | EIF2AK3 | 1.91199092 |
| 19 | NME2 | 1.90184094 |
| 20 | PLK3 | 1.87619892 |
| 21 | TAF1 | 1.64360974 |
| 22 | NUAK1 | 1.63750057 |
| 23 | PLK1 | 1.61202265 |
| 24 | MAP3K12 | 1.48130829 |
| 25 | VRK1 | 1.47275773 |
| 26 | BRSK1 | 1.45827176 |
| 27 | ACVR1B | 1.45613157 |
| 28 | TESK2 | 1.44731774 |
| 29 | MKNK1 | 1.41886707 |
| 30 | MST1R | 1.39849100 |
| 31 | TNIK | 1.32886697 |
| 32 | NEK2 | 1.29328763 |
| 33 | AURKB | 1.28542713 |
| 34 | PASK | 1.26948222 |
| 35 | EPHA2 | 1.25292427 |
| 36 | CHEK2 | 1.24314054 |
| 37 | CDK19 | 1.21878480 |
| 38 | ERBB3 | 1.17099767 |
| 39 | DYRK3 | 1.13967927 |
| 40 | SCYL2 | 1.06863503 |
| 41 | ATR | 1.06842433 |
| 42 | CDK7 | 1.06242270 |
| 43 | TESK1 | 1.03082151 |
| 44 | MKNK2 | 1.01934016 |
| 45 | AURKA | 1.00243397 |
| 46 | RPS6KB2 | 0.96386429 |
| 47 | PNCK | 0.96136533 |
| 48 | BCKDK | 0.91871271 |
| 49 | ERBB4 | 0.89625060 |
| 50 | BCR | 0.89280948 |
| 51 | CDK8 | 0.88866850 |
| 52 | EIF2AK2 | 0.88720647 |
| 53 | RPS6KA4 | 0.85257364 |
| 54 | PAK4 | 0.85252372 |
| 55 | LIMK1 | 0.83853728 |
| 56 | STK3 | 0.80999337 |
| 57 | RAF1 | 0.80343394 |
| 58 | CHEK1 | 0.76655201 |
| 59 | BRAF | 0.74958418 |
| 60 | MAP3K8 | 0.71132187 |
| 61 | PRKCI | 0.71082712 |
| 62 | ATM | 0.70668409 |
| 63 | BMPR1B | 0.65450054 |
| 64 | CSNK2A2 | 0.64039628 |
| 65 | CLK1 | 0.63591443 |
| 66 | ILK | 0.60805897 |
| 67 | DYRK2 | 0.60437080 |
| 68 | CCNB1 | 0.59363084 |
| 69 | CSNK2A1 | 0.58043432 |
| 70 | WNK3 | 0.52830932 |
| 71 | STK4 | 0.49773879 |
| 72 | STK38L | 0.47580360 |
| 73 | STK10 | 0.46917749 |
| 74 | CSNK1G1 | 0.46383015 |
| 75 | MAP3K2 | 0.43240286 |
| 76 | CDK1 | 0.43049146 |
| 77 | PAK1 | 0.42473607 |
| 78 | MAP2K7 | 0.42191974 |
| 79 | MET | 0.41651676 |
| 80 | FGFR1 | 0.40634153 |
| 81 | PIM2 | 0.40362703 |
| 82 | WNK4 | 0.39715628 |
| 83 | CSNK1E | 0.38710293 |
| 84 | CDK3 | 0.38235228 |
| 85 | CDK2 | 0.36490815 |
| 86 | ARAF | 0.35176823 |
| 87 | KDR | 0.34875635 |
| 88 | STK39 | 0.31999947 |
| 89 | MAP4K2 | 0.30668649 |
| 90 | TGFBR1 | 0.30038205 |
| 91 | BMX | 0.28754667 |
| 92 | ABL2 | 0.28291050 |
| 93 | MINK1 | 0.28286264 |
| 94 | LRRK2 | 0.27027899 |
| 95 | PLK2 | 0.25919566 |
| 96 | PRKDC | 0.25361591 |
| 97 | KSR1 | 0.25221402 |
| 98 | STK24 | 0.24959850 |
| 99 | DAPK1 | 0.23874802 |
| 100 | RPS6KA5 | 0.23256497 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 3.74886742 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.73358218 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 3.65968126 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.53769655 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.14670530 |
| 6 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.75800960 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 2.66685657 |
| 8 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.55722067 |
| 9 | RNA transport_Homo sapiens_hsa03013 | 2.52998081 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.49438583 |
| 11 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.49434732 |
| 12 | Base excision repair_Homo sapiens_hsa03410 | 2.46493909 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.42526018 |
| 14 | Protein export_Homo sapiens_hsa03060 | 2.39784039 |
| 15 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.32193037 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 2.31756686 |
| 17 | Parkinsons disease_Homo sapiens_hsa05012 | 2.12973602 |
| 18 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.02175918 |
| 19 | Cell cycle_Homo sapiens_hsa04110 | 1.91939952 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.79622150 |
| 21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.79529590 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.72854657 |
| 23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.64225302 |
| 24 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.54418995 |
| 25 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.52564941 |
| 26 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.45062502 |
| 27 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.39597436 |
| 28 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.35573832 |
| 29 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.35370210 |
| 30 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.31680275 |
| 31 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.30331021 |
| 32 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.29325209 |
| 33 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.28107980 |
| 34 | Alzheimers disease_Homo sapiens_hsa05010 | 1.24232741 |
| 35 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.21729407 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.19530786 |
| 37 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.16823725 |
| 38 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.15038029 |
| 39 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.10942158 |
| 40 | Carbon metabolism_Homo sapiens_hsa01200 | 1.10615177 |
| 41 | Sulfur relay system_Homo sapiens_hsa04122 | 1.07120545 |
| 42 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.06261552 |
| 43 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.04557719 |
| 44 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.01307129 |
| 45 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.96505863 |
| 46 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.96203692 |
| 47 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.95013051 |
| 48 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.90700507 |
| 49 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.86266705 |
| 50 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.85755386 |
| 51 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.81171467 |
| 52 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.78553676 |
| 53 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.78186226 |
| 54 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.73926379 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65862568 |
| 56 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.65590956 |
| 57 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.64248236 |
| 58 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.62560016 |
| 59 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.61089559 |
| 60 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60766703 |
| 61 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.59697732 |
| 62 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.53573904 |
| 63 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.51264322 |
| 64 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.50805580 |
| 65 | Thyroid cancer_Homo sapiens_hsa05216 | 0.50463915 |
| 66 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.50354769 |
| 67 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.47775084 |
| 68 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.46745873 |
| 69 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.45848611 |
| 70 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.44704683 |
| 71 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.43726173 |
| 72 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.43674453 |
| 73 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.38701645 |
| 74 | Peroxisome_Homo sapiens_hsa04146 | 0.37167379 |
| 75 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.36352679 |
| 76 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.36346685 |
| 77 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.36108469 |
| 78 | Phototransduction_Homo sapiens_hsa04744 | 0.33423697 |
| 79 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.33079865 |
| 80 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.32526215 |
| 81 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.30825034 |
| 82 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.28848585 |
| 83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.28105048 |
| 84 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.26525677 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.25501529 |
| 86 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.24456020 |
| 87 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.23574570 |
| 88 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.22252440 |
| 89 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.21987706 |
| 90 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.19601636 |
| 91 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.17970448 |
| 92 | Retinol metabolism_Homo sapiens_hsa00830 | 0.16995030 |
| 93 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.15261848 |
| 94 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.11884982 |
| 95 | Galactose metabolism_Homo sapiens_hsa00052 | 0.10988458 |
| 96 | Olfactory transduction_Homo sapiens_hsa04740 | 0.10687367 |
| 97 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.10420807 |
| 98 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.09845627 |
| 99 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.08669180 |
| 100 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.08525816 |

