MTA3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1formation of translation preinitiation complex (GO:0001731)4.97242112
2maturation of SSU-rRNA (GO:0030490)4.92920266
3mitotic metaphase plate congression (GO:0007080)4.73429325
4ribosome assembly (GO:0042255)4.54599281
5regulation of gene silencing by RNA (GO:0060966)4.52956800
6regulation of posttranscriptional gene silencing (GO:0060147)4.52956800
7regulation of gene silencing by miRNA (GO:0060964)4.52956800
8purine nucleobase biosynthetic process (GO:0009113)4.51068751
9nucleobase biosynthetic process (GO:0046112)4.46427710
10DNA replication checkpoint (GO:0000076)4.36125610
11protein localization to kinetochore (GO:0034501)4.16323056
12establishment of integrated proviral latency (GO:0075713)4.10947637
13ribosome biogenesis (GO:0042254)4.08698694
14positive regulation of chromosome segregation (GO:0051984)4.07218629
15regulation of spindle organization (GO:0090224)4.00754978
16mitotic nuclear envelope disassembly (GO:0007077)3.91304479
17metaphase plate congression (GO:0051310)3.89750788
18DNA replication initiation (GO:0006270)3.88194426
19regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.82830509
20DNA strand elongation involved in DNA replication (GO:0006271)3.82116930
21regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.80299924
22heterochromatin organization (GO:0070828)3.78265137
23paraxial mesoderm development (GO:0048339)3.74227473
24nuclear envelope disassembly (GO:0051081)3.70643413
25membrane disassembly (GO:0030397)3.70643413
26DNA strand elongation (GO:0022616)3.63415192
27protein localization to chromosome, centromeric region (GO:0071459)3.60106462
28attachment of spindle microtubules to kinetochore (GO:0008608)3.57999448
29ribonucleoprotein complex biogenesis (GO:0022613)3.55154881
30regulation of histone H3-K27 methylation (GO:0061085)3.55149457
31L-serine metabolic process (GO:0006563)3.47481984
32regulation of nuclear cell cycle DNA replication (GO:0033262)3.44042653
33regulation of mitotic spindle organization (GO:0060236)3.43364062
34DNA unwinding involved in DNA replication (GO:0006268)3.41099565
35establishment of chromosome localization (GO:0051303)3.40898297
36mitotic sister chromatid segregation (GO:0000070)3.40731595
37telomere maintenance via semi-conservative replication (GO:0032201)3.40003852
38mitotic chromosome condensation (GO:0007076)3.39780295
39folic acid metabolic process (GO:0046655)3.38896136
40rRNA processing (GO:0006364)3.36286509
41histone H2A monoubiquitination (GO:0035518)3.34539880
42histone exchange (GO:0043486)3.29292735
43ribosomal small subunit assembly (GO:0000028)3.28847860
44rRNA metabolic process (GO:0016072)3.27889904
45translational initiation (GO:0006413)3.26356042
46regulation of translation in response to stress (GO:0043555)3.24420777
47negative regulation of histone methylation (GO:0031061)3.21649542
48DNA replication-dependent nucleosome assembly (GO:0006335)3.21373427
49DNA replication-dependent nucleosome organization (GO:0034723)3.21373427
50DNA deamination (GO:0045006)3.21185884
51rRNA modification (GO:0000154)3.19599141
52nuclear envelope organization (GO:0006998)3.16326545
53telomere maintenance via recombination (GO:0000722)3.16161492
54anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.12930530
55regulation of chromosome segregation (GO:0051983)3.12582886
56ribosomal large subunit biogenesis (GO:0042273)3.11964171
57protein localization to chromosome (GO:0034502)3.10542484
58termination of RNA polymerase I transcription (GO:0006363)3.10174607
59regulation of helicase activity (GO:0051095)3.09922673
60intestinal epithelial cell development (GO:0060576)3.08664553
61negative regulation of chromosome segregation (GO:0051985)3.06753282
62CENP-A containing nucleosome assembly (GO:0034080)3.03845332
63regulation of translational termination (GO:0006449)3.03655348
64telomere maintenance via telomere lengthening (GO:0010833)3.02596695
65DNA replication-independent nucleosome assembly (GO:0006336)3.02264709
66DNA replication-independent nucleosome organization (GO:0034724)3.02264709
67spindle checkpoint (GO:0031577)3.01677682
68interferon-gamma secretion (GO:0072643)3.01154888
69mitotic recombination (GO:0006312)3.01142033
70transcription elongation from RNA polymerase I promoter (GO:0006362)3.01131202
71nuclear pore organization (GO:0006999)3.00819456
72negative regulation of DNA-dependent DNA replication (GO:2000104)2.99940484
73negative regulation of translational initiation (GO:0045947)2.99712278
74positive regulation of mitotic sister chromatid separation (GO:1901970)2.99661875
75positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.99661875
76positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.99661875
77viral transcription (GO:0019083)2.98441448
78chromatin remodeling at centromere (GO:0031055)2.98345007
79transcription from RNA polymerase I promoter (GO:0006360)2.98308512
80translational termination (GO:0006415)2.98068463
81trophectodermal cell differentiation (GO:0001829)2.97810868
82somatic hypermutation of immunoglobulin genes (GO:0016446)2.97791220
83somatic diversification of immune receptors via somatic mutation (GO:0002566)2.97791220
84negative regulation of mitotic sister chromatid separation (GO:2000816)2.97410715
85negative regulation of mitotic sister chromatid segregation (GO:0033048)2.97410715
86negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.97410715
87negative regulation of sister chromatid segregation (GO:0033046)2.97410715
88negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.96973045
89regulation of mitotic metaphase/anaphase transition (GO:0030071)2.96082042
90regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.95774040
91mitotic spindle checkpoint (GO:0071174)2.93753246
92regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.93088314
93regulation of exit from mitosis (GO:0007096)2.92124023
94mitotic spindle assembly checkpoint (GO:0007094)2.91680374
95pre-miRNA processing (GO:0031054)2.91048895
96spindle assembly checkpoint (GO:0071173)2.90053731
97sister chromatid segregation (GO:0000819)2.89402492
98negative regulation of DNA-templated transcription, elongation (GO:0032785)2.89171622
99negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.89171622
100ribosomal small subunit biogenesis (GO:0042274)2.88940910
101positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.86870975
102nuclear pore complex assembly (GO:0051292)2.86503952
103pseudouridine synthesis (GO:0001522)2.85630747
104translational elongation (GO:0006414)2.84400255
105mitotic sister chromatid cohesion (GO:0007064)2.83507256
106spliceosomal snRNP assembly (GO:0000387)2.83041688
107lung-associated mesenchyme development (GO:0060484)2.83018662
108regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.82919050
109regulation of mitotic spindle checkpoint (GO:1903504)2.82919050
110IMP biosynthetic process (GO:0006188)2.82578271
111regulation of sister chromatid segregation (GO:0033045)2.80695577
112regulation of mitotic sister chromatid separation (GO:0010965)2.80695577
113regulation of mitotic sister chromatid segregation (GO:0033047)2.80695577
114nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.80657027
115proteasome assembly (GO:0043248)2.79795110
116anterior/posterior axis specification, embryo (GO:0008595)2.77982986
117DNA strand renaturation (GO:0000733)2.75217473
118single strand break repair (GO:0000012)2.75123324
119establishment of viral latency (GO:0019043)2.74489579
120negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.74176416
121negative regulation of translation, ncRNA-mediated (GO:0040033)2.74176416
122regulation of translation, ncRNA-mediated (GO:0045974)2.74176416
123protein complex localization (GO:0031503)2.72547776
124ATP-dependent chromatin remodeling (GO:0043044)2.69143957
125regulation of histone H3-K9 methylation (GO:0051570)2.67529193
126regulation of cell fate specification (GO:0042659)2.66981019
127positive regulation of SMAD protein import into nucleus (GO:0060391)2.66349427
128notochord development (GO:0030903)2.64188392
129negative regulation of mitosis (GO:0045839)2.61167965
130cell fate commitment involved in formation of primary germ layer (GO:0060795)2.58439902
131kinetochore organization (GO:0051383)2.57790270
132regulation of centrosome cycle (GO:0046605)2.51437659
133lysine catabolic process (GO:0006554)2.51356666
134lysine metabolic process (GO:0006553)2.51356666
135establishment of protein localization to mitochondrial membrane (GO:0090151)2.47987077
136regulation of centriole replication (GO:0046599)2.47635878
137regulation of meiosis I (GO:0060631)2.47537322
138regulation of DNA methylation (GO:0044030)2.46166087
139IMP metabolic process (GO:0046040)2.44587138
140positive regulation of histone H3-K4 methylation (GO:0051571)2.44443274
141convergent extension (GO:0060026)2.43480954
142kinetochore assembly (GO:0051382)2.43135014
143DNA ligation (GO:0006266)2.43060316
144regulation of gene silencing (GO:0060968)2.41111674
145regulation of mitochondrial translation (GO:0070129)2.39395266
146DNA damage response, detection of DNA damage (GO:0042769)2.38132227
147inner ear receptor cell development (GO:0060119)2.37759959
148negative regulation of telomerase activity (GO:0051974)2.37431052
149chaperone-mediated protein transport (GO:0072321)2.36526493
150serine family amino acid biosynthetic process (GO:0009070)2.35924526
151negative regulation of nuclear division (GO:0051784)2.35745611
152telomere maintenance via telomerase (GO:0007004)2.35058832
153regulation of spindle checkpoint (GO:0090231)2.33918570
154chromatin assembly or disassembly (GO:0006333)2.32436757

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.10022317
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.93690370
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.74652225
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.24505936
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.21452961
6MYC_19079543_ChIP-ChIP_MESCs_Mouse3.13846967
7E2F4_17652178_ChIP-ChIP_JURKAT_Human2.95151923
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.77982277
9ETS1_20019798_ChIP-Seq_JURKAT_Human2.72970175
10* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.55553633
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.54320434
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.53948551
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.39365859
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.34596011
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.32595499
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.29802279
17GABP_17652178_ChIP-ChIP_JURKAT_Human2.24757367
18HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.21406577
19MYC_22102868_ChIP-Seq_BL_Human2.20264164
20NANOG_18555785_ChIP-Seq_MESCs_Mouse2.19320258
21VDR_23849224_ChIP-Seq_CD4+_Human2.12639057
22XRN2_22483619_ChIP-Seq_HELA_Human2.11644861
23EGR1_19374776_ChIP-ChIP_THP-1_Human2.10386026
24POU5F1_16153702_ChIP-ChIP_HESCs_Human2.04578515
25AR_21909140_ChIP-Seq_LNCAP_Human1.97092241
26RBPJ_22232070_ChIP-Seq_NCS_Mouse1.97081863
27NELFA_20434984_ChIP-Seq_ESCs_Mouse1.96955338
28SOX2_16153702_ChIP-ChIP_HESCs_Human1.94962863
29SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.92505023
30NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.91594426
31POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.87120473
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.84865236
33NANOG_16153702_ChIP-ChIP_HESCs_Human1.84427712
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.83518417
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.83387795
36MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.81563930
37GABP_19822575_ChIP-Seq_HepG2_Human1.80172071
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.76507034
39FOXP3_21729870_ChIP-Seq_TREG_Human1.75843894
40E2F1_18555785_ChIP-Seq_MESCs_Mouse1.72410950
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.70909171
42CIITA_25753668_ChIP-Seq_RAJI_Human1.70705697
43E2F1_21310950_ChIP-Seq_MCF-7_Human1.68149127
44HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.65898941
45KDM5A_27292631_Chip-Seq_BREAST_Human1.61632540
46KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.59475306
47DCP1A_22483619_ChIP-Seq_HELA_Human1.58948563
48SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.57545244
49THAP11_20581084_ChIP-Seq_MESCs_Mouse1.53049302
50TTF2_22483619_ChIP-Seq_HELA_Human1.52411433
51KLF4_18555785_ChIP-Seq_MESCs_Mouse1.51914339
52YY1_21170310_ChIP-Seq_MESCs_Mouse1.48560916
53NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.40645472
54GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.40247311
55STAT3_1855785_ChIP-Seq_MESCs_Mouse1.39781274
56PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.37000238
57FUS_26573619_Chip-Seq_HEK293_Human1.35813685
58YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.35239166
59KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.35099257
60KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.33326442
61KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.33326442
62KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.33326442
63ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.32798259
64CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.31908933
65ZNF274_21170338_ChIP-Seq_K562_Hela1.31012009
66HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.30558808
67* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.30498916
68NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.29109932
69MYC_18940864_ChIP-ChIP_HL60_Human1.28468423
70PADI4_21655091_ChIP-ChIP_MCF-7_Human1.28180392
71* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27803154
72DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.26207678
73SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.24485707
74ZNF263_19887448_ChIP-Seq_K562_Human1.22522571
75EWS_26573619_Chip-Seq_HEK293_Human1.21218692
76GATA1_26923725_Chip-Seq_HPCs_Mouse1.20565287
77* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.19989007
78TFEB_21752829_ChIP-Seq_HELA_Human1.18028277
79RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.17867053
80NOTCH1_21737748_ChIP-Seq_TLL_Human1.14852505
81SALL1_21062744_ChIP-ChIP_HESCs_Human1.14535214
82VDR_21846776_ChIP-Seq_THP-1_Human1.12886482
83CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12216146
84TCF3_18692474_ChIP-Seq_MEFs_Mouse1.10939682
85SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.10812648
86ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.10581006
87POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.10396859
88CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.10136399
89* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.09117669
90NANOG_21062744_ChIP-ChIP_HESCs_Human1.08497170
91SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.07435165
92* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.07259979
93IRF1_19129219_ChIP-ChIP_H3396_Human1.06038797
94ESR1_15608294_ChIP-ChIP_MCF-7_Human1.04757119
95FLI1_27457419_Chip-Seq_LIVER_Mouse1.04704197
96P300_19829295_ChIP-Seq_ESCs_Human1.04094333
97MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.03328419
98HOXB4_20404135_ChIP-ChIP_EML_Mouse1.02450895
99E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.00826387
100NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.00248007
101DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00061723
102* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.99641992
103SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.98808593
104NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.98511673
105ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.97805776
106HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.97224079
107* TBX3_20139965_ChIP-Seq_ESCs_Mouse0.96531493
108TP63_19390658_ChIP-ChIP_HaCaT_Human0.95900345
109* TBX3_20139965_ChIP-Seq_MESCs_Mouse0.95671003
110SOX2_18555785_ChIP-Seq_MESCs_Mouse0.95122831
111GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93913971
112ELF1_17652178_ChIP-ChIP_JURKAT_Human0.93872596
113NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.92920145
114ELK1_19687146_ChIP-ChIP_HELA_Human0.92439571
115OCT4_18692474_ChIP-Seq_MEFs_Mouse0.92135357
116SOX17_20123909_ChIP-Seq_XEN_Mouse0.92087100
117KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.91239035
118* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.91120853
119* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.90641712
120SPI1_23547873_ChIP-Seq_NB4_Human0.90291842
121* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.88262228
122TCF3_18692474_ChIP-Seq_MESCs_Mouse0.87602916
123SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.87511811
124KAP1_27257070_Chip-Seq_ESCs_Mouse0.86871713
125VDR_22108803_ChIP-Seq_LS180_Human0.86253770
126SOX2_18692474_ChIP-Seq_MEFs_Mouse0.86102482
127SRF_21415370_ChIP-Seq_HL-1_Mouse0.85896711
128SOX9_26525672_Chip-Seq_HEART_Mouse0.85599461
129TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.85540849
130POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.85364559
131PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.84934279
132ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.84897994
133FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.84564547
134PCGF2_27294783_Chip-Seq_ESCs_Mouse0.83211043
135SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.83151624
136SOX2_18692474_ChIP-Seq_MESCs_Mouse0.83085714
137GBX2_23144817_ChIP-Seq_PC3_Human0.81012460
138* TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.79369776
139* NANOG_16518401_ChIP-PET_MESCs_Mouse0.78151907

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.93663441
2MP0003111_abnormal_nucleus_morphology4.89891254
3MP0004957_abnormal_blastocyst_morpholog4.66454696
4MP0010094_abnormal_chromosome_stability4.38072790
5MP0003077_abnormal_cell_cycle3.97326288
6MP0008057_abnormal_DNA_replication3.35182613
7MP0008058_abnormal_DNA_repair2.80752324
8MP0003890_abnormal_embryonic-extraembry2.77046829
9MP0002396_abnormal_hematopoietic_system2.75966931
10MP0003123_paternal_imprinting2.67131704
11MP0003136_yellow_coat_color2.61078178
12MP0001730_embryonic_growth_arrest2.57350730
13MP0008877_abnormal_DNA_methylation2.38374677
14MP0010030_abnormal_orbit_morphology2.34257064
15MP0008932_abnormal_embryonic_tissue2.31671446
16MP0003718_maternal_effect2.23895100
17MP0000350_abnormal_cell_proliferation2.23889142
18MP0008007_abnormal_cellular_replicative2.22757719
19MP0008260_abnormal_autophagy2.20735086
20MP0002254_reproductive_system_inflammat2.19013389
21MP0010352_gastrointestinal_tract_polyps2.06418999
22MP0000566_synostosis2.00287680
23MP0003786_premature_aging1.99117980
24MP0005397_hematopoietic_system_phenotyp1.97932489
25MP0001545_abnormal_hematopoietic_system1.97932489
26MP0003122_maternal_imprinting1.91704067
27MP0010307_abnormal_tumor_latency1.87294850
28MP0001672_abnormal_embryogenesis/_devel1.84667498
29MP0005380_embryogenesis_phenotype1.84667498
30MP0003937_abnormal_limbs/digits/tail_de1.81122810
31MP0003763_abnormal_thymus_physiology1.77533796
32MP0001697_abnormal_embryo_size1.77079520
33MP0009333_abnormal_splenocyte_physiolog1.73413927
34MP0003880_abnormal_central_pattern1.73409024
35MP0002938_white_spotting1.69171208
36MP0002080_prenatal_lethality1.67043362
37MP0003984_embryonic_growth_retardation1.62068614
38MP0000490_abnormal_crypts_of1.59796712
39MP0002086_abnormal_extraembryonic_tissu1.58069413
40MP0002088_abnormal_embryonic_growth/wei1.57932470
41MP0002084_abnormal_developmental_patter1.54138959
42MP0002019_abnormal_tumor_incidence1.53995938
43MP0002085_abnormal_embryonic_tissue1.46681916
44MP0002697_abnormal_eye_size1.46191469
45MP0000703_abnormal_thymus_morphology1.44224218
46MP0002398_abnormal_bone_marrow1.42696267
47MP0003787_abnormal_imprinting1.41395326
48MP0000313_abnormal_cell_death1.41336669
49MP0001188_hyperpigmentation1.38155822
50MP0005076_abnormal_cell_differentiation1.37900062
51MP0009278_abnormal_bone_marrow1.37802903
52MP0004133_heterotaxia1.35919767
53MP0010234_abnormal_vibrissa_follicle1.35749723
54MP0002722_abnormal_immune_system1.32172183
55MP0002233_abnormal_nose_morphology1.32143899
56MP0004808_abnormal_hematopoietic_stem1.30293523
57MP0001299_abnormal_eye_distance/1.27104775
58MP0001286_abnormal_eye_development1.26860499
59MP0001346_abnormal_lacrimal_gland1.26490382
60MP0004859_abnormal_synaptic_plasticity1.25333013
61MP0005499_abnormal_olfactory_system1.23698413
62MP0005394_taste/olfaction_phenotype1.23698413
63MP0002653_abnormal_ependyma_morphology1.22565274
64MP0002210_abnormal_sex_determination1.21270833
65MP0004264_abnormal_extraembryonic_tissu1.19870631
66MP0005671_abnormal_response_to1.19281803
67MP0000689_abnormal_spleen_morphology1.18952030
68MP0003941_abnormal_skin_development1.17698858
69MP0003861_abnormal_nervous_system1.17208884
70MP0001485_abnormal_pinna_reflex1.17084924
71MP0003567_abnormal_fetal_cardiomyocyte1.16878570
72MP0000537_abnormal_urethra_morphology1.15310968
73MP0003938_abnormal_ear_development1.14757728
74MP0000428_abnormal_craniofacial_morphol1.14583596
75MP0004270_analgesia1.14031982
76MP0001145_abnormal_male_reproductive1.13269701
77MP0008789_abnormal_olfactory_epithelium1.13227649
78MP0005423_abnormal_somatic_nervous1.12661474
79MP0000049_abnormal_middle_ear1.09188975
80MP0005621_abnormal_cell_physiology1.08961522
81MP0001929_abnormal_gametogenesis1.07877418
82MP0004197_abnormal_fetal_growth/weight/1.06959417
83MP0009840_abnormal_foam_cell1.06057528
84MP0006072_abnormal_retinal_apoptosis1.04276811
85MP0002796_impaired_skin_barrier1.04223236
86MP0000778_abnormal_nervous_system1.03108351
87MP0005075_abnormal_melanosome_morpholog1.02931763
88MP0000631_abnormal_neuroendocrine_gland1.02595218
89MP0000358_abnormal_cell_content/1.02271838
90MP0001529_abnormal_vocalization1.02092390
91MP0000653_abnormal_sex_gland1.01883601
92MP0002429_abnormal_blood_cell1.01620410
93MP0005384_cellular_phenotype1.01243330
94MP0000579_abnormal_nail_morphology1.00606236
95MP0000716_abnormal_immune_system0.99248605
96MP0002736_abnormal_nociception_after0.99225691
97MP0001177_atelectasis0.97849650
98MP0002111_abnormal_tail_morphology0.97601206
99MP0002751_abnormal_autonomic_nervous0.92536442
100MP0003942_abnormal_urinary_system0.90333076
101MP0009379_abnormal_foot_pigmentation0.90045392
102MP0003566_abnormal_cell_adhesion0.85109687
103MP0003755_abnormal_palate_morphology0.84727420
104MP0005451_abnormal_body_composition0.84695021
105MP0001849_ear_inflammation0.84528325
106MP0002734_abnormal_mechanical_nocicepti0.84037563
107MP0003283_abnormal_digestive_organ0.83617983
108MP0001800_abnormal_humoral_immune0.82790536
109MP0000647_abnormal_sebaceous_gland0.82121488
110MP0003121_genomic_imprinting0.81822858
111MP0009672_abnormal_birth_weight0.81740820
112MP0005501_abnormal_skin_physiology0.80994359
113MP0003866_abnormal_defecation0.80429608
114MP0001968_abnormal_touch/_nociception0.80027895
115MP0003635_abnormal_synaptic_transmissio0.79548242
116MP0009697_abnormal_copulation0.79546879
117MP0001984_abnormal_olfaction0.79394763
118MP0004947_skin_inflammation0.78517358
119MP0002420_abnormal_adaptive_immunity0.78358755
120MP0002184_abnormal_innervation0.78354616
121MP0000465_gastrointestinal_hemorrhage0.77896854
122MP0001819_abnormal_immune_cell0.76920859
123MP0003699_abnormal_female_reproductive0.76438473
124MP0001486_abnormal_startle_reflex0.76112400
125MP0003698_abnormal_male_reproductive0.75463618
126MP0005310_abnormal_salivary_gland0.75268077
127MP0002152_abnormal_brain_morphology0.74889848
128MP0006276_abnormal_autonomic_nervous0.74317313
129MP0009703_decreased_birth_body0.73411123
130MP0000432_abnormal_head_morphology0.73242275
131MP0000858_altered_metastatic_potential0.72981749
132MP0005389_reproductive_system_phenotype0.72210383
133MP0003935_abnormal_craniofacial_develop0.71226572
134MP0009745_abnormal_behavioral_response0.71137238
135MP0005395_other_phenotype0.71131977
136MP0002102_abnormal_ear_morphology0.71105376
137MP0002272_abnormal_nervous_system0.70688539
138MP0003448_altered_tumor_morphology0.70636786
139MP0008770_decreased_survivor_rate0.70340860
140MP0005551_abnormal_eye_electrophysiolog0.69815874
141MP0000955_abnormal_spinal_cord0.69725532
142MP0006292_abnormal_olfactory_placode0.69554069
143MP0009780_abnormal_chondrocyte_physiolo0.69441850
144MP0001119_abnormal_female_reproductive0.69079119
145MP0002723_abnormal_immune_serum0.68462768
146MP0002877_abnormal_melanocyte_morpholog0.67678803
147MP0005023_abnormal_wound_healing0.66868293
148MP0002160_abnormal_reproductive_system0.64440570
149MP0003119_abnormal_digestive_system0.64222638
150MP0001293_anophthalmia0.64138440
151MP0003315_abnormal_perineum_morphology0.63993510
152MP0000627_abnormal_mammary_gland0.63341584
153MP0005377_hearing/vestibular/ear_phenot0.62322719
154MP0003878_abnormal_ear_physiology0.62322719
155MP0002452_abnormal_antigen_presenting0.61818060
156MP0003221_abnormal_cardiomyocyte_apopto0.60279590
157MP0000477_abnormal_intestine_morphology0.59629576
158MP0002006_tumorigenesis0.58471555
159MP0001919_abnormal_reproductive_system0.57627503
160MP0002405_respiratory_system_inflammati0.57371116
161MP0002161_abnormal_fertility/fecundity0.56265647

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.54416076
2Breast hypoplasia (HP:0003187)4.59811951
3Cerebral hypomyelination (HP:0006808)4.37495805
4Carpal bone hypoplasia (HP:0001498)4.32809130
5Septo-optic dysplasia (HP:0100842)4.10667345
6Ependymoma (HP:0002888)3.52396440
7Impulsivity (HP:0100710)3.42422075
8Rough bone trabeculation (HP:0100670)3.37220813
9Patellar aplasia (HP:0006443)3.30973712
10Colon cancer (HP:0003003)3.30554577
11Premature ovarian failure (HP:0008209)3.28012629
12Abnormality of cells of the erythroid lineage (HP:0012130)3.26181130
13Aplasia/Hypoplasia of the patella (HP:0006498)3.17905500
14Ureteral duplication (HP:0000073)3.14147893
15Abnormal number of erythroid precursors (HP:0012131)3.10483557
16Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.09920512
17Abnormality of the anterior horn cell (HP:0006802)3.09736612
18Degeneration of anterior horn cells (HP:0002398)3.09736612
19Selective tooth agenesis (HP:0001592)3.02742005
20Chromsome breakage (HP:0040012)2.82993431
21Oral leukoplakia (HP:0002745)2.82507377
22Absent septum pellucidum (HP:0001331)2.79917793
23Absent radius (HP:0003974)2.79188670
24Reticulocytopenia (HP:0001896)2.78415682
25Nephroblastoma (Wilms tumor) (HP:0002667)2.77889309
26Abnormality of the labia minora (HP:0012880)2.77436023
27Microretrognathia (HP:0000308)2.70889905
28Abnormal lung lobation (HP:0002101)2.67768181
29Abnormality of the umbilical cord (HP:0010881)2.67357883
30Medulloblastoma (HP:0002885)2.66683417
31Absent thumb (HP:0009777)2.65494299
32Maternal diabetes (HP:0009800)2.63040053
33Hepatoblastoma (HP:0002884)2.62238639
34Embryonal renal neoplasm (HP:0011794)2.61754180
35Basal cell carcinoma (HP:0002671)2.61744259
36CNS hypomyelination (HP:0003429)2.59323570
37Abnormality of the septum pellucidum (HP:0007375)2.57147441
38Chromosomal breakage induced by crosslinking agents (HP:0003221)2.56983467
39Aplasia involving forearm bones (HP:0009822)2.56901722
40Absent forearm bone (HP:0003953)2.56901722
41Spinal muscular atrophy (HP:0007269)2.56401896
42Prominent nose (HP:0000448)2.55768651
43Agnosia (HP:0010524)2.55116330
44Secondary amenorrhea (HP:0000869)2.54250588
45Rhabdomyosarcoma (HP:0002859)2.53861053
46Increased nuchal translucency (HP:0010880)2.50198117
47Entropion (HP:0000621)2.48027991
48Abnormality of the preputium (HP:0100587)2.43005712
49Overlapping toe (HP:0001845)2.41694638
50Aplastic anemia (HP:0001915)2.36591593
51Atrophy/Degeneration involving motor neurons (HP:0007373)2.35446476
52Bilateral microphthalmos (HP:0007633)2.32659579
53Abnormality of chromosome stability (HP:0003220)2.32436991
54Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.32060045
55Abnormal trabecular bone morphology (HP:0100671)2.31246082
56Multiple enchondromatosis (HP:0005701)2.30191923
57Supernumerary spleens (HP:0009799)2.29515779
58Optic nerve hypoplasia (HP:0000609)2.28932651
59Glioma (HP:0009733)2.27983430
60Hyperglycinuria (HP:0003108)2.27470959
61Ectopic kidney (HP:0000086)2.24809515
62Abnormality of the astrocytes (HP:0100707)2.22387627
63Astrocytoma (HP:0009592)2.22387627
64Bone marrow hypocellularity (HP:0005528)2.20713474
65Premature graying of hair (HP:0002216)2.20604359
66Macrocytic anemia (HP:0001972)2.19052413
67Choanal stenosis (HP:0000452)2.17981402
68Myelodysplasia (HP:0002863)2.16436157
69Progressive muscle weakness (HP:0003323)2.16106686
70Personality changes (HP:0000751)2.13332528
71IgM deficiency (HP:0002850)2.13205213
72T lymphocytopenia (HP:0005403)2.11712565
73Neoplasm of the pancreas (HP:0002894)2.09080507
74Squamous cell carcinoma (HP:0002860)2.08912991
75Anophthalmia (HP:0000528)2.08026072
76Horseshoe kidney (HP:0000085)2.07659184
77Meckel diverticulum (HP:0002245)2.06591081
78Abnormality of the fingertips (HP:0001211)2.05992762
79Duplication of thumb phalanx (HP:0009942)2.05061485
80Abnormality of the ileum (HP:0001549)2.04655493
81Partial duplication of thumb phalanx (HP:0009944)2.04300565
82Neoplasm of the oral cavity (HP:0100649)2.03351112
83Triphalangeal thumb (HP:0001199)2.03085066
84Patent foramen ovale (HP:0001655)2.02001933
85Trismus (HP:0000211)2.00628360
86Lymphoma (HP:0002665)1.99813418
87Pili torti (HP:0003777)1.99582779
88Aqueductal stenosis (HP:0002410)1.98046463
89Sparse eyelashes (HP:0000653)1.97986874
90Abnormality of cochlea (HP:0000375)1.97960912
91IgG deficiency (HP:0004315)1.97813347
92Pustule (HP:0200039)1.97220499
93Aplasia/Hypoplasia of the sternum (HP:0006714)1.95416811
94Sparse lateral eyebrow (HP:0005338)1.95061409
95Cleft eyelid (HP:0000625)1.94384859
96Rectal fistula (HP:0100590)1.94248363
97Rectovaginal fistula (HP:0000143)1.94248363
98Esophageal atresia (HP:0002032)1.93999820
99Abnormality of serine family amino acid metabolism (HP:0010894)1.93929409
100Abnormality of glycine metabolism (HP:0010895)1.93929409
101Stenosis of the external auditory canal (HP:0000402)1.93469935
102Bifid tongue (HP:0010297)1.92795709
103Hyperglycinemia (HP:0002154)1.91567452
104Chronic otitis media (HP:0000389)1.91459665
105Cafe-au-lait spot (HP:0000957)1.90552131
106Postnatal microcephaly (HP:0005484)1.88883271
107Pallor (HP:0000980)1.88258153
108Small intestinal stenosis (HP:0012848)1.87421406
109Duodenal stenosis (HP:0100867)1.87421406
110Cellular immunodeficiency (HP:0005374)1.85123129
111Breast aplasia (HP:0100783)1.85116289
112Abnormality of T cell number (HP:0011839)1.84103026
113Death in infancy (HP:0001522)1.82677343
114Hypoplasia of the radius (HP:0002984)1.82472740
115Aplasia/Hypoplasia of the uvula (HP:0010293)1.82303654
116Biliary tract neoplasm (HP:0100574)1.82032915
117Volvulus (HP:0002580)1.81683112
118Abnormality of the fetal cardiovascular system (HP:0010948)1.79676878
119Abnormal umbilical cord blood vessels (HP:0011403)1.79676878
120Single umbilical artery (HP:0001195)1.79676878
121Neoplasm of striated muscle (HP:0009728)1.78440551
122Vaginal fistula (HP:0004320)1.77694697
123Abnormal spermatogenesis (HP:0008669)1.77680095
124Abnormal biliary tract morphology (HP:0012440)1.76389860
125Amaurosis fugax (HP:0100576)1.76248567
126Absent eyebrow (HP:0002223)1.76034038
127Abnormality of the duodenum (HP:0002246)1.75933792
128Abnormality of the lacrimal duct (HP:0011481)1.75119428
129Recurrent bronchitis (HP:0002837)1.74898276
130Male infertility (HP:0003251)1.74692371
131Cutaneous finger syndactyly (HP:0010554)1.74683001
132Cortical dysplasia (HP:0002539)1.74508823
133Oligodactyly (HP:0012165)1.73525275
134Blepharitis (HP:0000498)1.72897361
135Embryonal neoplasm (HP:0002898)1.72326111
136Facial cleft (HP:0002006)1.71052067
137Trigonocephaly (HP:0000243)1.70558971
138Bronchomalacia (HP:0002780)1.69246555
139Aplasia/Hypoplasia of the breasts (HP:0010311)1.69202230
140Intestinal atresia (HP:0011100)1.69146382
141Intestinal fistula (HP:0100819)1.68998105
142Abnormality of abdominal situs (HP:0011620)1.68771991
143Abdominal situs inversus (HP:0003363)1.68771991
144Abnormality of the middle phalanges of the toes (HP:0010183)1.68282723
145Preaxial foot polydactyly (HP:0001841)1.67827905
146Partial duplication of the phalanx of hand (HP:0009999)1.67778729
147Pancreatic islet-cell hyperplasia (HP:0004510)1.66980324
148Neoplasm of the adrenal cortex (HP:0100641)1.66631248
149Short hallux (HP:0010109)1.66136263
150Cutaneous syndactyly (HP:0012725)1.65719538
151Abnormality of the carotid arteries (HP:0005344)1.64034032
152Hypoplastic female external genitalia (HP:0012815)1.63982808
153Hemivertebrae (HP:0002937)1.63669211
154Homocystinuria (HP:0002156)1.62775809
155Abnormality of homocysteine metabolism (HP:0010919)1.62775809
156Coronal craniosynostosis (HP:0004440)1.61615941
157Myokymia (HP:0002411)1.61449894
158Neoplasm of the colon (HP:0100273)1.60509277
159Abnormality of serum amino acid levels (HP:0003112)1.59074623
160Abnormality of methionine metabolism (HP:0010901)1.58467651
161Aplasia/Hypoplasia of the hallux (HP:0008362)1.58295215
162Gastrointestinal atresia (HP:0002589)1.56662896
163Broad thumb (HP:0011304)1.56232496
164Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.55802862
165Abnormality of aspartate family amino acid metabolism (HP:0010899)1.55376289
166Pendular nystagmus (HP:0012043)1.54905914
167Renal hypoplasia (HP:0000089)1.54024982
168Abnormal hair whorl (HP:0010721)1.53779662
169Hyperinsulinemic hypoglycemia (HP:0000825)1.52110581

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.90210684
2WEE14.85874347
3TSSK63.41469056
4NEK23.24947214
5NME22.89506203
6EPHA22.76137272
7TTK2.63912726
8VRK22.63285377
9CDC72.55717944
10TAF12.54499611
11TNIK2.32195756
12PLK42.21246775
13NEK12.13976971
14PLK12.05089868
15EIF2AK11.96387025
16PNCK1.96053270
17FGFR21.94767576
18BRSK21.93171616
19MAP4K11.90473715
20PBK1.82737913
21EPHA41.78401033
22DYRK31.77618009
23ALK1.76601602
24RPS6KB21.70350123
25STK101.69688913
26CASK1.66932660
27PLK31.66152433
28BRSK11.64421475
29EEF2K1.63705663
30CDK191.59858384
31CDK121.58881931
32ACVR1B1.54210210
33NME11.50215788
34AURKB1.46140176
35CDK41.45290612
36STK161.40269386
37CDK71.38166063
38NUAK11.37749953
39CHEK21.37677074
40MAP3K81.35304251
41MST41.34411702
42STK38L1.32916529
43WNK31.30945212
44LATS11.28451525
45AURKA1.25415995
46SRPK11.22058988
47FGFR11.21901292
48DYRK21.21803761
49LATS21.17689464
50ATR1.15712461
51EIF2AK31.14498834
52TAOK11.14299999
53WNK41.11034157
54OXSR11.09536652
55CHEK11.08455202
56CAMK1G1.08364857
57MAP3K91.05944544
58BMPR1B1.04561414
59CCNB11.04472264
60TYRO31.04333957
61PIM11.03992906
62TESK21.02185158
63STK390.97859586
64AKT30.96192823
65PASK0.95636679
66TRIM280.95516150
67ARAF0.92613281
68PRKCI0.92273356
69TLK10.91484585
70PLK20.90044810
71VRK10.89403768
72CDK20.89186055
73ZAP700.87538007
74STK30.82577122
75BRAF0.80814615
76LRRK20.79012908
77RAF10.76557403
78MAPKAPK30.75968418
79CAMK1D0.74902543
80SCYL20.74642492
81NTRK20.72564349
82MARK10.72335493
83PIM20.71363277
84STK240.69051158
85FLT30.68932213
86SMG10.68602291
87PAK10.67330574
88PKN20.66825240
89RPS6KA40.66697062
90ATM0.65614643
91MTOR0.63783876
92CDK60.63566921
93MELK0.63162453
94MKNK20.62829990
95PRKCG0.62630640
96STK380.59409592
97EIF2AK20.59349946
98NTRK10.58756013
99MINK10.58483973
100PAK40.56688439
101NLK0.56070053
102CDK10.55708186
103STK40.54677066
104PDK30.54061487
105PDK40.54061487
106CSNK2A20.53639483
107TXK0.51943941
108ITK0.51673586
109BRD40.51520506
110BMX0.48900191
111MAP2K20.48453475
112CSNK1E0.48404419
113NTRK30.47960339
114UHMK10.44960117
115SGK2230.44624113
116SGK4940.44624113
117MAP3K110.42848000
118MARK30.41591392
119CSNK1G20.40974850
120MET0.40028974
121CSNK2A10.39892129
122DYRK1A0.39232105
123NEK60.39103847
124TGFBR10.37299439
125CDK11A0.36999633
126MAP3K40.36659066
127GSK3B0.36412626
128CDK180.36065035
129CDK150.35817095
130TRIB30.34361757
131CSNK1G10.33697103
132GRK60.33097542
133KSR20.32440827
134ZAK0.32206939
135CSNK1G30.30877153
136DAPK10.29499350
137MKNK10.29401586
138KIT0.28372072
139MAP3K30.27701977
140MAP3K100.27649826
141MAP2K30.27613061
142TEC0.27429698
143MAPK110.26288787
144PDK20.25179684
145PRKDC0.24293668
146BTK0.23755848
147MAPK100.21920973

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.03056289
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.98429258
3Vitamin B6 metabolism_Homo sapiens_hsa007503.87837660
4Mismatch repair_Homo sapiens_hsa034303.59950168
5RNA polymerase_Homo sapiens_hsa030203.50630247
6RNA transport_Homo sapiens_hsa030133.38791511
7Proteasome_Homo sapiens_hsa030502.92786858
8Spliceosome_Homo sapiens_hsa030402.83152125
9Base excision repair_Homo sapiens_hsa034102.82595975
10Ribosome_Homo sapiens_hsa030102.82438428
11Cell cycle_Homo sapiens_hsa041102.78015034
12Homologous recombination_Homo sapiens_hsa034402.56792413
13Nucleotide excision repair_Homo sapiens_hsa034202.48775849
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.17447724
15Pyrimidine metabolism_Homo sapiens_hsa002402.09388629
16Basal transcription factors_Homo sapiens_hsa030221.99850285
17Fanconi anemia pathway_Homo sapiens_hsa034601.75328402
18p53 signaling pathway_Homo sapiens_hsa041151.62490028
19mRNA surveillance pathway_Homo sapiens_hsa030151.62109844
20RNA degradation_Homo sapiens_hsa030181.57934754
21Regulation of autophagy_Homo sapiens_hsa041401.57896542
22Oocyte meiosis_Homo sapiens_hsa041141.55062895
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.54835665
24Non-homologous end-joining_Homo sapiens_hsa034501.45743833
25Propanoate metabolism_Homo sapiens_hsa006401.44396095
26Basal cell carcinoma_Homo sapiens_hsa052171.40849511
27Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.38085082
28Antigen processing and presentation_Homo sapiens_hsa046121.36647777
29Steroid biosynthesis_Homo sapiens_hsa001001.32434681
30Nicotine addiction_Homo sapiens_hsa050331.31718795
31Epstein-Barr virus infection_Homo sapiens_hsa051691.31600543
32One carbon pool by folate_Homo sapiens_hsa006701.30594930
33Primary immunodeficiency_Homo sapiens_hsa053401.29091727
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.28179836
35Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.26881827
36Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.22796771
37Pyruvate metabolism_Homo sapiens_hsa006201.19283069
38Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.19192425
39Huntingtons disease_Homo sapiens_hsa050161.18668653
40Oxidative phosphorylation_Homo sapiens_hsa001901.18047040
41Purine metabolism_Homo sapiens_hsa002301.16995141
42Wnt signaling pathway_Homo sapiens_hsa043101.14391442
43Parkinsons disease_Homo sapiens_hsa050121.12866179
44Folate biosynthesis_Homo sapiens_hsa007901.09508937
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.04845353
46Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.03015059
47Protein export_Homo sapiens_hsa030601.02288201
48Pentose phosphate pathway_Homo sapiens_hsa000301.00155703
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.98193614
502-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.95136623
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.94922629
52Thyroid cancer_Homo sapiens_hsa052160.93275114
53Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.93012257
54Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.90791855
55Lysine degradation_Homo sapiens_hsa003100.90182163
56Cardiac muscle contraction_Homo sapiens_hsa042600.90040825
57Arginine and proline metabolism_Homo sapiens_hsa003300.89727260
58Vitamin digestion and absorption_Homo sapiens_hsa049770.83997001
59Glycerophospholipid metabolism_Homo sapiens_hsa005640.81264287
60mTOR signaling pathway_Homo sapiens_hsa041500.80668818
61Viral carcinogenesis_Homo sapiens_hsa052030.78463205
62Herpes simplex infection_Homo sapiens_hsa051680.76488438
63Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.76036014
64HTLV-I infection_Homo sapiens_hsa051660.74592414
65Fatty acid elongation_Homo sapiens_hsa000620.73864026
66Carbon metabolism_Homo sapiens_hsa012000.70656220
67Taste transduction_Homo sapiens_hsa047420.70525261
68Alzheimers disease_Homo sapiens_hsa050100.70125851
69Cysteine and methionine metabolism_Homo sapiens_hsa002700.67919304
70Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.66980541
71Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.64168361
72Cyanoamino acid metabolism_Homo sapiens_hsa004600.61684718
73Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.61086427
74Butanoate metabolism_Homo sapiens_hsa006500.59822157
75Phototransduction_Homo sapiens_hsa047440.58715417
76Acute myeloid leukemia_Homo sapiens_hsa052210.56521668
77MicroRNAs in cancer_Homo sapiens_hsa052060.54418941
78Colorectal cancer_Homo sapiens_hsa052100.54356260
79Hippo signaling pathway_Homo sapiens_hsa043900.53660912
80T cell receptor signaling pathway_Homo sapiens_hsa046600.53508623
81Melanogenesis_Homo sapiens_hsa049160.53242726
82beta-Alanine metabolism_Homo sapiens_hsa004100.52871618
83Fatty acid metabolism_Homo sapiens_hsa012120.52627832
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51512608
85Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.50423557
86Apoptosis_Homo sapiens_hsa042100.50027156
87Sulfur relay system_Homo sapiens_hsa041220.49881013
88Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.49323792
89Metabolic pathways_Homo sapiens_hsa011000.48517778
90Fructose and mannose metabolism_Homo sapiens_hsa000510.46960675
91Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46887455
92Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.45584013
93Measles_Homo sapiens_hsa051620.44780666
94Axon guidance_Homo sapiens_hsa043600.43462842
95Arginine biosynthesis_Homo sapiens_hsa002200.43140859
96Shigellosis_Homo sapiens_hsa051310.42556111
97B cell receptor signaling pathway_Homo sapiens_hsa046620.42444845
98Biosynthesis of amino acids_Homo sapiens_hsa012300.41735057
99Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.41569957
100Non-small cell lung cancer_Homo sapiens_hsa052230.41246498
101Inositol phosphate metabolism_Homo sapiens_hsa005620.41063585
102Glutamatergic synapse_Homo sapiens_hsa047240.40785721
103Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.40261976
104GABAergic synapse_Homo sapiens_hsa047270.39981728
105Endocytosis_Homo sapiens_hsa041440.39823502
106Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.39594664
107Insulin secretion_Homo sapiens_hsa049110.39136649
108Small cell lung cancer_Homo sapiens_hsa052220.37472476
109Hematopoietic cell lineage_Homo sapiens_hsa046400.37135221
110Chronic myeloid leukemia_Homo sapiens_hsa052200.36465807
111Fat digestion and absorption_Homo sapiens_hsa049750.36313080
112Glutathione metabolism_Homo sapiens_hsa004800.36066533
113FoxO signaling pathway_Homo sapiens_hsa040680.35289970
114Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.35161917
115Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.34821992
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.34557604
117Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.34419982
118Hepatitis B_Homo sapiens_hsa051610.34331096
119Circadian rhythm_Homo sapiens_hsa047100.34144314
120Selenocompound metabolism_Homo sapiens_hsa004500.34109041
121NF-kappa B signaling pathway_Homo sapiens_hsa040640.33876873
122Thyroid hormone synthesis_Homo sapiens_hsa049180.33853521
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.33595856
124Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.33193265
125Olfactory transduction_Homo sapiens_hsa047400.32342602
126Intestinal immune network for IgA production_Homo sapiens_hsa046720.31749829
127Notch signaling pathway_Homo sapiens_hsa043300.31078693
128Glucagon signaling pathway_Homo sapiens_hsa049220.31057349
129Fatty acid degradation_Homo sapiens_hsa000710.31006577
130Synaptic vesicle cycle_Homo sapiens_hsa047210.30811008
131Endometrial cancer_Homo sapiens_hsa052130.30579376
132Nitrogen metabolism_Homo sapiens_hsa009100.30508726
133Amphetamine addiction_Homo sapiens_hsa050310.30500727
134Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.30245062
135Maturity onset diabetes of the young_Homo sapiens_hsa049500.28718133
136Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28381316
137NOD-like receptor signaling pathway_Homo sapiens_hsa046210.27784963
138Transcriptional misregulation in cancer_Homo sapiens_hsa052020.26753018
139Renal cell carcinoma_Homo sapiens_hsa052110.25935871
140Tight junction_Homo sapiens_hsa045300.25815429
141Jak-STAT signaling pathway_Homo sapiens_hsa046300.25348517
142Pathways in cancer_Homo sapiens_hsa052000.24881368
143HIF-1 signaling pathway_Homo sapiens_hsa040660.24782433
144Drug metabolism - other enzymes_Homo sapiens_hsa009830.24441752
145Prostate cancer_Homo sapiens_hsa052150.23015570
146Phosphatidylinositol signaling system_Homo sapiens_hsa040700.22478539
147VEGF signaling pathway_Homo sapiens_hsa043700.22200787
148Neurotrophin signaling pathway_Homo sapiens_hsa047220.21464592
149Bladder cancer_Homo sapiens_hsa052190.20971884
150Leukocyte transendothelial migration_Homo sapiens_hsa046700.19253661
151Influenza A_Homo sapiens_hsa051640.18624607
152TGF-beta signaling pathway_Homo sapiens_hsa043500.18288447
153Galactose metabolism_Homo sapiens_hsa000520.17205994
154Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.17195049
155Estrogen signaling pathway_Homo sapiens_hsa049150.16630315
156Regulation of actin cytoskeleton_Homo sapiens_hsa048100.15669046
157Adherens junction_Homo sapiens_hsa045200.15402166
158Hedgehog signaling pathway_Homo sapiens_hsa043400.14174215

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