MTCO2P2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ATP synthesis coupled proton transport (GO:0015986)6.32510578
2energy coupled proton transport, down electrochemical gradient (GO:0015985)6.32510578
3ovulation cycle (GO:0042698)6.27267737
4behavioral response to nicotine (GO:0035095)5.73343528
5pyrimidine nucleobase catabolic process (GO:0006208)5.71402571
6mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.55071071
7ribosomal small subunit biogenesis (GO:0042274)5.48569312
8tyrosine phosphorylation of STAT protein (GO:0007260)5.46510361
9regulation of female gonad development (GO:2000194)5.44212488
10response to pheromone (GO:0019236)5.29129802
11regulation of bile acid biosynthetic process (GO:0070857)5.19820032
12pyrimidine deoxyribonucleotide catabolic process (GO:0009223)5.17663976
13viral transcription (GO:0019083)4.95625775
14ribosomal small subunit assembly (GO:0000028)4.95321383
15chaperone-mediated protein transport (GO:0072321)4.87338015
16regulation of transmission of nerve impulse (GO:0051969)4.82897788
17translational termination (GO:0006415)4.75967769
18epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.70707069
19nucleobase catabolic process (GO:0046113)4.58693297
20protein neddylation (GO:0045116)4.43463497
21pyrimidine nucleotide catabolic process (GO:0006244)4.38096528
22base-excision repair, AP site formation (GO:0006285)4.30671572
23GTP biosynthetic process (GO:0006183)4.27749868
24respiratory electron transport chain (GO:0022904)4.15370446
25electron transport chain (GO:0022900)4.13112074
26cell proliferation in forebrain (GO:0021846)4.06646312
27maturation of SSU-rRNA (GO:0030490)4.05188699
28mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.93316685
29translational elongation (GO:0006414)3.85279248
30SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.75653580
31protein targeting to ER (GO:0045047)3.73995538
32establishment of protein localization to mitochondrial membrane (GO:0090151)3.72919796
33hydrogen ion transmembrane transport (GO:1902600)3.71345638
34cotranslational protein targeting to membrane (GO:0006613)3.70117742
35cellular protein complex disassembly (GO:0043624)3.69103235
36UTP biosynthetic process (GO:0006228)3.62405354
37purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.61495555
38establishment of mitochondrion localization (GO:0051654)3.60721428
39transmission of nerve impulse (GO:0019226)3.59743668
40epithelial cilium movement (GO:0003351)3.57729735
41establishment of protein localization to endoplasmic reticulum (GO:0072599)3.56869355
42viral life cycle (GO:0019058)3.55117212
43protein localization to endoplasmic reticulum (GO:0070972)3.54934048
44regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.53448394
45purine nucleoside triphosphate biosynthetic process (GO:0009145)3.50706418
46establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.48036441
47mitochondrion transport along microtubule (GO:0047497)3.48036441
48neurofilament cytoskeleton organization (GO:0060052)3.47027288
49negative regulation of protein tyrosine kinase activity (GO:0061099)3.42827267
50ATP biosynthetic process (GO:0006754)3.40573140
51synaptic vesicle maturation (GO:0016188)3.39843892
52DNA deamination (GO:0045006)3.39512459
53nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.32988875
54protein complex biogenesis (GO:0070271)3.32671973
55positive regulation of neurological system process (GO:0031646)3.29931237
56adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.29853757
57UTP metabolic process (GO:0046051)3.29755615
58axonal fasciculation (GO:0007413)3.28023269
59protein complex disassembly (GO:0043241)3.15077156
60proton transport (GO:0015992)3.14804322
61eating behavior (GO:0042755)3.12892165
62ribonucleoside triphosphate biosynthetic process (GO:0009201)3.08925589
63mitochondrial respiratory chain complex I assembly (GO:0032981)3.08493102
64NADH dehydrogenase complex assembly (GO:0010257)3.08493102
65mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.08493102
66hydrogen transport (GO:0006818)3.06687106
67regulation of microtubule-based movement (GO:0060632)3.06322702
68neuron recognition (GO:0008038)3.05966171
69synaptic transmission, cholinergic (GO:0007271)3.03063773
70sequestering of actin monomers (GO:0042989)2.98290675
71regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.97088770
72macromolecular complex disassembly (GO:0032984)2.94959358
73head development (GO:0060322)2.91078537
74cilium movement (GO:0003341)2.89292303
75axonemal dynein complex assembly (GO:0070286)2.86416057
76negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.86324535
77somite development (GO:0061053)2.84394138
78genetic imprinting (GO:0071514)2.82648236
79mitochondrial respiratory chain complex assembly (GO:0033108)2.81966027
80water-soluble vitamin biosynthetic process (GO:0042364)2.81854411
81CTP biosynthetic process (GO:0006241)2.81163673
82CTP metabolic process (GO:0046036)2.81163673
83pyrimidine-containing compound catabolic process (GO:0072529)2.80635401
84limb development (GO:0060173)2.79284455
85appendage development (GO:0048736)2.79284455
86regulation of cilium movement (GO:0003352)2.78727543
87negative regulation of neurological system process (GO:0031645)2.77969624
88synaptic transmission, glutamatergic (GO:0035249)2.76989286
89amine catabolic process (GO:0009310)2.75444238
90cellular biogenic amine catabolic process (GO:0042402)2.75444238
91dendritic spine morphogenesis (GO:0060997)2.73430895
92protein polyglutamylation (GO:0018095)2.73348647
93substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.73141875
94substrate-independent telencephalic tangential migration (GO:0021826)2.73141875
95translational initiation (GO:0006413)2.73047094
96endoderm formation (GO:0001706)2.71128857
97spinal cord association neuron differentiation (GO:0021527)2.66882700
98protein peptidyl-prolyl isomerization (GO:0000413)2.66499803
99calcium ion-dependent exocytosis (GO:0017156)2.66099583
100axon ensheathment in central nervous system (GO:0032291)2.64289672

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.49996986
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.80262163
3NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.22445670
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.94409681
5VDR_22108803_ChIP-Seq_LS180_Human2.63605295
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.45193808
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.24909216
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.13327494
9EED_16625203_ChIP-ChIP_MESCs_Mouse2.11972416
10EZH2_27294783_Chip-Seq_ESCs_Mouse2.10151365
11BMI1_23680149_ChIP-Seq_NPCS_Mouse2.08417173
12SUZ12_27294783_Chip-Seq_ESCs_Mouse2.06381230
13REST_21632747_ChIP-Seq_MESCs_Mouse2.05764692
14CBX2_27304074_Chip-Seq_ESCs_Mouse2.01025448
15ZNF274_21170338_ChIP-Seq_K562_Hela1.97916428
16IRF1_19129219_ChIP-ChIP_H3396_Human1.87158607
17JARID2_20075857_ChIP-Seq_MESCs_Mouse1.86833566
18SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.78129273
19GATA1_26923725_Chip-Seq_HPCs_Mouse1.71868094
20REST_18959480_ChIP-ChIP_MESCs_Mouse1.68233653
21RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.59932996
22RNF2_27304074_Chip-Seq_NSC_Mouse1.59752518
23RNF2_18974828_ChIP-Seq_MESCs_Mouse1.58447421
24EZH2_18974828_ChIP-Seq_MESCs_Mouse1.58447421
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.57292291
26TDRD3_21172665_ChIP-Seq_MCF-7_Human1.56725681
27ETV2_25802403_ChIP-Seq_MESCs_Mouse1.56603171
28SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.56217916
29SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.55367893
30SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.55286579
31RNF2_27304074_Chip-Seq_ESCs_Mouse1.51211220
32CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.50377377
33GABP_17652178_ChIP-ChIP_JURKAT_Human1.49615748
34CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.49377932
35CTCF_27219007_Chip-Seq_Bcells_Human1.49010987
36SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.47021553
37EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.46910691
38IKZF1_21737484_ChIP-ChIP_HCT116_Human1.37539144
39RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.37228720
40TP53_22573176_ChIP-Seq_HFKS_Human1.36414357
41SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.35788260
42HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.34427356
43P53_22127205_ChIP-Seq_FIBROBLAST_Human1.32907043
44SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.32547947
45ERA_21632823_ChIP-Seq_H3396_Human1.31825575
46GBX2_23144817_ChIP-Seq_PC3_Human1.31730674
47MYC_19829295_ChIP-Seq_ESCs_Human1.31229014
48NANOG_20526341_ChIP-Seq_ESCs_Human1.29772045
49NCOR_22424771_ChIP-Seq_293T_Human1.28233233
50STAT6_21828071_ChIP-Seq_BEAS2B_Human1.26820300
51MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25691054
52PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.25252020
53TAF2_19829295_ChIP-Seq_ESCs_Human1.23123831
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.21460156
55RING1B_27294783_Chip-Seq_ESCs_Mouse1.20533658
56GATA3_21878914_ChIP-Seq_MCF-7_Human1.20021545
57MTF2_20144788_ChIP-Seq_MESCs_Mouse1.19536151
58EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.17112390
59CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.16924802
60STAT1_20625510_ChIP-Seq_HELA_Human1.16836830
61GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.15279225
62CTBP1_25329375_ChIP-Seq_LNCAP_Human1.15142539
63IGF1R_20145208_ChIP-Seq_DFB_Human1.14561270
64TP53_20018659_ChIP-ChIP_R1E_Mouse1.14310467
65CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.09358675
66RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.09023963
67SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.08901285
68RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.08766585
69TP53_22127205_ChIP-Seq_IMR90_Human1.08474779
70MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.07270898
71ERG_21242973_ChIP-ChIP_JURKAT_Human1.07123983
72OCT4_19829295_ChIP-Seq_ESCs_Human1.06734103
73ZFP57_27257070_Chip-Seq_ESCs_Mouse1.06261649
74BCL6_27268052_Chip-Seq_Bcells_Human1.03875521
75ETS1_20019798_ChIP-Seq_JURKAT_Human1.03131856
76WDR5_24793694_ChIP-Seq_LNCAP_Human1.02163284
77E2F1_20622854_ChIP-Seq_HELA_Human1.01622119
78E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.01355219
79SMAD3_21741376_ChIP-Seq_ESCs_Human1.00393913
80FOXH1_21741376_ChIP-Seq_ESCs_Human1.00266666
81MYC_18940864_ChIP-ChIP_HL60_Human0.99396877
82SOX2_19829295_ChIP-Seq_ESCs_Human0.98933160
83NANOG_19829295_ChIP-Seq_ESCs_Human0.98933160
84NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.97584731
85CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.96940038
86PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.96812565
87GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96763903
88P68_20966046_ChIP-Seq_HELA_Human0.96645478
89OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.96343538
90SA1_27219007_Chip-Seq_Bcells_Human0.96121870
91PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.95267656
92CTCF_20526341_ChIP-Seq_ESCs_Human0.94363320
93YY1_22570637_ChIP-Seq_MALME-3M_Human0.93607748
94CBP_20019798_ChIP-Seq_JUKART_Human0.93014919
95IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.93014919
96ELF1_20517297_ChIP-Seq_JURKAT_Human0.91953734
97P53_21459846_ChIP-Seq_SAOS-2_Human0.91821786
98SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.91645897
99NOTCH1_21737748_ChIP-Seq_TLL_Human0.91644390
100OCT4_20526341_ChIP-Seq_ESCs_Human0.91355848

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003787_abnormal_imprinting4.20855420
2MP0005646_abnormal_pituitary_gland4.20410949
3MP0009379_abnormal_foot_pigmentation4.07435036
4MP0006292_abnormal_olfactory_placode3.76209525
5MP0003315_abnormal_perineum_morphology3.64616020
6MP0003122_maternal_imprinting3.58795635
7MP0003121_genomic_imprinting2.97151832
8MP0003879_abnormal_hair_cell2.70401145
9MP0005187_abnormal_penis_morphology2.59321660
10MP0008877_abnormal_DNA_methylation2.49835189
11MP0003123_paternal_imprinting2.39712574
12MP0006276_abnormal_autonomic_nervous2.25344662
13MP0003646_muscle_fatigue2.16021040
14MP0004142_abnormal_muscle_tone2.08341482
15MP0008789_abnormal_olfactory_epithelium1.95034606
16MP0002653_abnormal_ependyma_morphology1.94000413
17MP0004742_abnormal_vestibular_system1.88600361
18MP0000778_abnormal_nervous_system1.81809153
19MP0002272_abnormal_nervous_system1.78673466
20MP0004859_abnormal_synaptic_plasticity1.76934276
21MP0004885_abnormal_endolymph1.74701692
22MP0004130_abnormal_muscle_cell1.73712350
23MP0003880_abnormal_central_pattern1.70158408
24MP0005394_taste/olfaction_phenotype1.69925477
25MP0005499_abnormal_olfactory_system1.69925477
26MP0001485_abnormal_pinna_reflex1.58802329
27MP0009046_muscle_twitch1.57574726
28MP0009745_abnormal_behavioral_response1.56055156
29MP0001440_abnormal_grooming_behavior1.54437550
30MP0002733_abnormal_thermal_nociception1.53580016
31MP0003635_abnormal_synaptic_transmissio1.52266670
32MP0003283_abnormal_digestive_organ1.50995565
33MP0001968_abnormal_touch/_nociception1.49617638
34MP0002160_abnormal_reproductive_system1.47392101
35MP0004133_heterotaxia1.40375148
36MP0000049_abnormal_middle_ear1.40227331
37MP0005423_abnormal_somatic_nervous1.39636283
38MP0002876_abnormal_thyroid_physiology1.39408459
39MP0001970_abnormal_pain_threshold1.37349705
40MP0003878_abnormal_ear_physiology1.35733056
41MP0005377_hearing/vestibular/ear_phenot1.35733056
42MP0005389_reproductive_system_phenotype1.34796753
43MP0001529_abnormal_vocalization1.34003603
44MP0004145_abnormal_muscle_electrophysio1.32748306
45MP0000613_abnormal_salivary_gland1.32597455
46MP0000955_abnormal_spinal_cord1.30757533
47MP0005551_abnormal_eye_electrophysiolog1.30524289
48MP0002163_abnormal_gland_morphology1.30490919
49MP0002638_abnormal_pupillary_reflex1.29773753
50MP0002063_abnormal_learning/memory/cond1.28986625
51MP0002557_abnormal_social/conspecific_i1.27379872
52MP0001984_abnormal_olfaction1.26408972
53MP0002184_abnormal_innervation1.24793648
54MP0002734_abnormal_mechanical_nocicepti1.23443628
55MP0002735_abnormal_chemical_nociception1.23181964
56MP0001919_abnormal_reproductive_system1.20931978
57MP0002837_dystrophic_cardiac_calcinosis1.19716112
58MP0005083_abnormal_biliary_tract1.18901791
59MP0002064_seizures1.16495845
60MP0002736_abnormal_nociception_after1.15200782
61MP0008872_abnormal_physiological_respon1.13040112
62MP0001486_abnormal_startle_reflex1.12579142
63MP0002752_abnormal_somatic_nervous1.12279329
64MP0002572_abnormal_emotion/affect_behav1.11348883
65MP0005195_abnormal_posterior_eye1.04208895
66MP0001963_abnormal_hearing_physiology1.04059565
67MP0002102_abnormal_ear_morphology1.03914341
68MP0001727_abnormal_embryo_implantation1.02805623
69MP0002067_abnormal_sensory_capabilities1.02202821
70MP0005645_abnormal_hypothalamus_physiol1.01860040
71MP0000026_abnormal_inner_ear1.01329948
72MP0001986_abnormal_taste_sensitivity1.01040983
73MP0003942_abnormal_urinary_system0.98139829
74MP0002882_abnormal_neuron_morphology0.97100411
75MP0000631_abnormal_neuroendocrine_gland0.96451750
76MP0004147_increased_porphyrin_level0.95367775
77MP0008875_abnormal_xenobiotic_pharmacok0.94476147
78MP0000534_abnormal_ureter_morphology0.93238631
79MP0004043_abnormal_pH_regulation0.89357597
80MP0001905_abnormal_dopamine_level0.83658378
81MP0001293_anophthalmia0.83364867
82MP0003011_delayed_dark_adaptation0.82968331
83MP0003938_abnormal_ear_development0.81528731
84MP0004924_abnormal_behavior0.80294748
85MP0005386_behavior/neurological_phenoty0.80294748
86MP0003136_yellow_coat_color0.79876482
87MP0000678_abnormal_parathyroid_gland0.78207169
88MP0002938_white_spotting0.77577091
89MP0001348_abnormal_lacrimal_gland0.76170779
90MP0006072_abnormal_retinal_apoptosis0.74422452
91MP0005084_abnormal_gallbladder_morpholo0.74016949
92MP0002152_abnormal_brain_morphology0.73327840
93MP0008775_abnormal_heart_ventricle0.72927124
94MP0001542_abnormal_bone_strength0.71194638
95MP0001502_abnormal_circadian_rhythm0.68539020
96MP0002229_neurodegeneration0.66438475
97MP0000372_irregular_coat_pigmentation0.65836246
98MP0002066_abnormal_motor_capabilities/c0.63410820
99MP0002210_abnormal_sex_determination0.62761278
100MP0002138_abnormal_hepatobiliary_system0.61834337

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)3.78297649
2Molar tooth sign on MRI (HP:0002419)3.71189949
3Abnormality of midbrain morphology (HP:0002418)3.71189949
4Acute necrotizing encephalopathy (HP:0006965)3.58246407
5Reticulocytopenia (HP:0001896)3.34184241
6Abnormal mitochondria in muscle tissue (HP:0008316)3.28679748
7Abnormality of the labia minora (HP:0012880)3.27661049
8Acute encephalopathy (HP:0006846)3.26649376
9Anosmia (HP:0000458)3.26226111
10Myokymia (HP:0002411)3.26167523
11Agitation (HP:0000713)3.20294455
12Hyperthyroidism (HP:0000836)3.19173252
13Stenosis of the external auditory canal (HP:0000402)3.18801770
14Type II lissencephaly (HP:0007260)3.15737409
153-Methylglutaconic aciduria (HP:0003535)3.14485489
16Hypogonadotrophic hypogonadism (HP:0000044)3.06676458
17Pancreatic fibrosis (HP:0100732)3.01424948
18Abnormal respiratory epithelium morphology (HP:0012253)2.99486647
19Abnormal respiratory motile cilium morphology (HP:0005938)2.99486647
20Absent rod-and cone-mediated responses on ERG (HP:0007688)2.92945852
21Sclerocornea (HP:0000647)2.88242462
22Optic disc pallor (HP:0000543)2.87050835
23Mitochondrial inheritance (HP:0001427)2.84585375
24Progressive macrocephaly (HP:0004481)2.83380092
25Abnormal number of erythroid precursors (HP:0012131)2.77971919
26Pancreatic cysts (HP:0001737)2.69852355
27Lipid accumulation in hepatocytes (HP:0006561)2.69416600
28True hermaphroditism (HP:0010459)2.67867530
29Polyphagia (HP:0002591)2.67765232
30Pallor (HP:0000980)2.64624273
31Lissencephaly (HP:0001339)2.63103975
32Pachygyria (HP:0001302)2.62467671
33Aplasia/Hypoplasia of the spleen (HP:0010451)2.59698282
34Nephronophthisis (HP:0000090)2.56517199
35Asplenia (HP:0001746)2.54546678
36Aplasia/Hypoplasia of the brainstem (HP:0007362)2.53840565
37Hypoplasia of the brainstem (HP:0002365)2.53840565
38Large eyes (HP:0001090)2.50175128
39Increased hepatocellular lipid droplets (HP:0006565)2.50009548
40Occipital encephalocele (HP:0002085)2.49536131
41Retinal dysplasia (HP:0007973)2.49518549
42Progressive cerebellar ataxia (HP:0002073)2.47198228
43Abnormal hemoglobin (HP:0011902)2.42766372
44Decreased electroretinogram (ERG) amplitude (HP:0000654)2.41705564
45Failure to thrive in infancy (HP:0001531)2.41628463
46Renal Fanconi syndrome (HP:0001994)2.39069723
47Cerebellar dysplasia (HP:0007033)2.39056972
48Increased CSF lactate (HP:0002490)2.37610459
49Pendular nystagmus (HP:0012043)2.37280631
50Amblyopia (HP:0000646)2.32369926
51Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.29179406
52Abnormality of renal resorption (HP:0011038)2.26731877
53Increased intramyocellular lipid droplets (HP:0012240)2.25548725
54Septo-optic dysplasia (HP:0100842)2.24871089
55Abnormality of cochlea (HP:0000375)2.24825111
56Absent/shortened dynein arms (HP:0200106)2.24271164
57Dynein arm defect of respiratory motile cilia (HP:0012255)2.24271164
58Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.22848726
59Decreased activity of mitochondrial respiratory chain (HP:0008972)2.22848726
60Male pseudohermaphroditism (HP:0000037)2.21825237
61Abnormal rod and cone electroretinograms (HP:0008323)2.16722801
62Absent thumb (HP:0009777)2.15996492
63Medial flaring of the eyebrow (HP:0010747)2.15638403
64Abolished electroretinogram (ERG) (HP:0000550)2.15579024
65Abnormal respiratory motile cilium physiology (HP:0012261)2.15524223
66Abnormality of the aortic arch (HP:0012303)2.13399007
67Chronic hepatic failure (HP:0100626)2.12443228
68Macrocytic anemia (HP:0001972)2.09250100
69Limb dystonia (HP:0002451)2.09111635
70Congenital stationary night blindness (HP:0007642)2.08532467
71Supernumerary spleens (HP:0009799)2.07983626
72Increased muscle lipid content (HP:0009058)2.06034944
73Delayed puberty (HP:0000823)2.06012265
74Abnormality of the renal medulla (HP:0100957)2.05027304
75Hypomagnesemia (HP:0002917)2.03105140
76Abnormal ciliary motility (HP:0012262)2.02341710
77Optic nerve coloboma (HP:0000588)2.01238389
78Hyperphosphatemia (HP:0002905)2.00365032
79Anencephaly (HP:0002323)1.98973764
80Anophthalmia (HP:0000528)1.96871133
81Optic nerve hypoplasia (HP:0000609)1.95610863
82Colon cancer (HP:0003003)1.93574404
83Morphological abnormality of the inner ear (HP:0011390)1.92639704
84Abnormality of magnesium homeostasis (HP:0004921)1.92546787
85Urinary bladder sphincter dysfunction (HP:0002839)1.92199747
86Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.88785689
87Anterior segment dysgenesis (HP:0007700)1.87600021
88Cystic liver disease (HP:0006706)1.86950659
89Abnormal drinking behavior (HP:0030082)1.86750405
90Polydipsia (HP:0001959)1.86750405
91Cerebral edema (HP:0002181)1.85724494
92Infertility (HP:0000789)1.84885105
93Microretrognathia (HP:0000308)1.83585009
94Short chin (HP:0000331)1.81818269
95Abnormality of the heme biosynthetic pathway (HP:0010472)1.81249778
96Enlarged kidneys (HP:0000105)1.80476704
97Oligomenorrhea (HP:0000876)1.80071375
98Abnormal number of incisors (HP:0011064)1.79436188
99Morphological abnormality of the middle ear (HP:0008609)1.79244031
100Gait imbalance (HP:0002141)1.78880419

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SIK24.26631768
2WNK33.67713621
3WNK42.98327809
4DYRK22.64579759
5PTK62.52944780
6FRK2.28053340
7CASK2.19491105
8PIK3CA2.14713234
9CDK191.95146093
10PINK11.93918454
11MAP3K111.86661336
12MINK11.81183390
13ADRBK21.80576711
14EPHA41.74779540
15NTRK21.74078248
16PRKCG1.69308754
17MARK11.65859592
18EPHB21.56685049
19GRK11.53745414
20TNIK1.53247660
21NUAK11.46952543
22STK111.35539750
23PRKCH1.33900456
24PAK31.32621167
25DYRK1B1.32037104
26TXK1.31071230
27TYRO31.30463834
28DYRK31.27003175
29MAPK131.26874641
30CAMKK21.25799140
31BRSK11.22248114
32PRKD21.19817642
33ADRBK11.13947708
34MAP2K71.13368910
35NEK21.05440618
36ZAK1.05379684
37LIMK11.02788146
38TIE11.02389731
39BCKDK1.02046075
40SGK2231.01635103
41SGK4941.01635103
42PRKCZ1.00869170
43MARK21.00591800
44CAMKK11.00303370
45MAP4K21.00008806
46CAMK10.99401369
47DYRK1A0.91953930
48INSRR0.90211288
49GRK70.87354012
50ABL20.86170558
51STK160.85904749
52CDC70.84714161
53PLK20.84306572
54TLK10.82581397
55PRKACA0.81142828
56DAPK20.80983875
57CSNK1G20.80777522
58DMPK0.80596812
59CSNK1E0.73423632
60BMPR1B0.68975599
61AURKA0.68076701
62RPS6KA20.67795517
63SGK10.67271927
64OXSR10.65399909
65WNK10.65250779
66PRKCQ0.64965679
67CDK50.62602136
68MAPK150.61713439
69GRK50.60217215
70PAK10.59021792
71PRKCI0.57212460
72SGK30.57128942
73PKN10.56231388
74KIT0.55802073
75PRKCD0.55774405
76IRAK10.55172719
77TAOK30.53148608
78OBSCN0.52478812
79PRKCE0.52103783
80VRK20.51986488
81MUSK0.51934309
82NTRK10.51117357
83PRKCA0.50869766
84CSNK2A20.50677367
85MAP3K40.50417716
86PHKG10.49944686
87PHKG20.49944686
88PRKACG0.45721541
89RPS6KA60.45175386
90LRRK20.44837821
91ILK0.44830182
92CDK140.42496447
93KDR0.42240164
94PRKG10.41715207
95CSNK1A10.41144288
96CAMK2A0.41102206
97MAP3K90.40653499
98TEC0.39764924
99DAPK30.38585448
100TAOK10.37712884

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.76789899
2Ribosome_Homo sapiens_hsa030104.22424236
3Parkinsons disease_Homo sapiens_hsa050124.03044113
4Cardiac muscle contraction_Homo sapiens_hsa042603.76002386
5Alzheimers disease_Homo sapiens_hsa050103.01911665
6Huntingtons disease_Homo sapiens_hsa050162.88132182
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.73930014
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.59137290
9Nicotine addiction_Homo sapiens_hsa050332.58160095
10Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.46588275
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.04271628
12Linoleic acid metabolism_Homo sapiens_hsa005911.79044541
13alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.77196093
14Phototransduction_Homo sapiens_hsa047441.63731969
15Butanoate metabolism_Homo sapiens_hsa006501.59260430
16RNA polymerase_Homo sapiens_hsa030201.55118055
17Sulfur relay system_Homo sapiens_hsa041221.53450399
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.47075693
19Synaptic vesicle cycle_Homo sapiens_hsa047211.38075013
20Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.37848965
21Morphine addiction_Homo sapiens_hsa050321.33347078
22Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.32630372
23Fat digestion and absorption_Homo sapiens_hsa049751.31308378
24Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.28335486
25Caffeine metabolism_Homo sapiens_hsa002321.27053399
26Olfactory transduction_Homo sapiens_hsa047401.23282373
27Steroid biosynthesis_Homo sapiens_hsa001001.21199668
28Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.20463140
29GABAergic synapse_Homo sapiens_hsa047271.18255312
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.17883373
31Ether lipid metabolism_Homo sapiens_hsa005651.14732765
32Peroxisome_Homo sapiens_hsa041461.11619425
33Insulin secretion_Homo sapiens_hsa049111.01443203
34Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.97764949
35Steroid hormone biosynthesis_Homo sapiens_hsa001400.96367641
36Chemical carcinogenesis_Homo sapiens_hsa052040.95159216
37Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.94648719
38Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.91045873
39Nitrogen metabolism_Homo sapiens_hsa009100.88779675
40Tryptophan metabolism_Homo sapiens_hsa003800.88732478
41Glutamatergic synapse_Homo sapiens_hsa047240.88176955
42Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.88009049
43Carbohydrate digestion and absorption_Homo sapiens_hsa049730.82778678
44Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.81997893
45Primary bile acid biosynthesis_Homo sapiens_hsa001200.80198571
46Maturity onset diabetes of the young_Homo sapiens_hsa049500.78522092
47Serotonergic synapse_Homo sapiens_hsa047260.77770361
48Retinol metabolism_Homo sapiens_hsa008300.76372739
49Taste transduction_Homo sapiens_hsa047420.74607730
50Axon guidance_Homo sapiens_hsa043600.74478039
51Dopaminergic synapse_Homo sapiens_hsa047280.70288786
52Homologous recombination_Homo sapiens_hsa034400.67720985
53Protein export_Homo sapiens_hsa030600.67661433
54beta-Alanine metabolism_Homo sapiens_hsa004100.67143966
55Metabolic pathways_Homo sapiens_hsa011000.66272843
56SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66153677
57Arachidonic acid metabolism_Homo sapiens_hsa005900.65539381
58Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.64748194
59Glycerolipid metabolism_Homo sapiens_hsa005610.64338349
60Collecting duct acid secretion_Homo sapiens_hsa049660.63752749
61Circadian entrainment_Homo sapiens_hsa047130.63228641
62Melanoma_Homo sapiens_hsa052180.62940492
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.62583816
64Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61718954
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.61712227
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61701055
67Fatty acid degradation_Homo sapiens_hsa000710.58828679
68Ovarian steroidogenesis_Homo sapiens_hsa049130.54826766
69Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.51278951
70Cholinergic synapse_Homo sapiens_hsa047250.50730451
71Salivary secretion_Homo sapiens_hsa049700.50567856
72Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.49634750
73Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.48941889
74RNA degradation_Homo sapiens_hsa030180.46384441
75Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.46300698
76Folate biosynthesis_Homo sapiens_hsa007900.45800943
77Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.42400734
78Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.42024181
79Pancreatic secretion_Homo sapiens_hsa049720.41623559
80Pyrimidine metabolism_Homo sapiens_hsa002400.41524819
81Notch signaling pathway_Homo sapiens_hsa043300.40891270
82Proteasome_Homo sapiens_hsa030500.40588077
83Selenocompound metabolism_Homo sapiens_hsa004500.39478897
84Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.38849520
85Amphetamine addiction_Homo sapiens_hsa050310.38214622
86Arginine and proline metabolism_Homo sapiens_hsa003300.37665967
87Tyrosine metabolism_Homo sapiens_hsa003500.37207573
88Basal cell carcinoma_Homo sapiens_hsa052170.37079153
89Starch and sucrose metabolism_Homo sapiens_hsa005000.36887275
90Mineral absorption_Homo sapiens_hsa049780.35285868
91Propanoate metabolism_Homo sapiens_hsa006400.34484026
92Ras signaling pathway_Homo sapiens_hsa040140.34127100
93Fanconi anemia pathway_Homo sapiens_hsa034600.33427735
94Primary immunodeficiency_Homo sapiens_hsa053400.33111380
95Cocaine addiction_Homo sapiens_hsa050300.31682352
96Oxytocin signaling pathway_Homo sapiens_hsa049210.31132239
97Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29156309
98Glycerophospholipid metabolism_Homo sapiens_hsa005640.28926886
99Calcium signaling pathway_Homo sapiens_hsa040200.27881621
100Thyroid hormone synthesis_Homo sapiens_hsa049180.27656793

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »