MTF2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)4.75934201
2purine nucleobase biosynthetic process (GO:0009113)4.52739191
3DNA replication initiation (GO:0006270)4.51894782
4protein localization to kinetochore (GO:0034501)4.50035539
5nucleobase biosynthetic process (GO:0046112)4.49993647
6nuclear pore organization (GO:0006999)4.35727251
7DNA replication checkpoint (GO:0000076)4.29573687
8DNA strand elongation involved in DNA replication (GO:0006271)4.24829647
9metaphase plate congression (GO:0051310)4.20904163
10DNA strand elongation (GO:0022616)4.09214243
11chromatin remodeling at centromere (GO:0031055)4.07966422
12DNA unwinding involved in DNA replication (GO:0006268)4.06998080
13CENP-A containing nucleosome assembly (GO:0034080)4.06970394
14nuclear pore complex assembly (GO:0051292)4.06032471
15ribosome assembly (GO:0042255)4.00795509
16kinetochore organization (GO:0051383)3.99667382
17mitotic nuclear envelope disassembly (GO:0007077)3.96085384
18DNA replication-dependent nucleosome organization (GO:0034723)3.95165378
19DNA replication-dependent nucleosome assembly (GO:0006335)3.95165378
20telomere maintenance via semi-conservative replication (GO:0032201)3.93015372
21regulation of spindle organization (GO:0090224)3.91951406
22protein localization to chromosome, centromeric region (GO:0071459)3.89363286
23maturation of SSU-rRNA (GO:0030490)3.89312485
24DNA replication-independent nucleosome organization (GO:0034724)3.85868172
25DNA replication-independent nucleosome assembly (GO:0006336)3.85868172
26DNA double-strand break processing (GO:0000729)3.82330299
27somatic hypermutation of immunoglobulin genes (GO:0016446)3.82094847
28somatic diversification of immune receptors via somatic mutation (GO:0002566)3.82094847
29ribosome biogenesis (GO:0042254)3.73477580
30attachment of spindle microtubules to kinetochore (GO:0008608)3.71311621
31formation of translation preinitiation complex (GO:0001731)3.69639395
32replication fork processing (GO:0031297)3.69236008
33regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.69129514
34regulation of mitotic spindle checkpoint (GO:1903504)3.69129514
35regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.68286341
36nuclear envelope disassembly (GO:0051081)3.67850811
37membrane disassembly (GO:0030397)3.67850811
38establishment of chromosome localization (GO:0051303)3.66305241
39telomere maintenance via recombination (GO:0000722)3.65867629
40kinetochore assembly (GO:0051382)3.64679064
41regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.64041017
42establishment of protein localization to mitochondrial membrane (GO:0090151)3.62833590
43mitotic recombination (GO:0006312)3.61803394
44histone exchange (GO:0043486)3.60259563
45regulation of nuclear cell cycle DNA replication (GO:0033262)3.59886034
46IMP biosynthetic process (GO:0006188)3.56738768
47mitotic sister chromatid segregation (GO:0000070)3.54289683
48positive regulation of chromosome segregation (GO:0051984)3.50566225
49regulation of helicase activity (GO:0051095)3.45560703
50spindle checkpoint (GO:0031577)3.44648979
51mitotic chromosome condensation (GO:0007076)3.44180771
52protein K6-linked ubiquitination (GO:0085020)3.43113637
53telomere maintenance via telomere lengthening (GO:0010833)3.42212421
54regulation of histone H3-K9 methylation (GO:0051570)3.40805737
55ribosomal small subunit assembly (GO:0000028)3.37491185
56negative regulation of chromosome segregation (GO:0051985)3.36458226
57ribonucleoprotein complex biogenesis (GO:0022613)3.35020706
58regulation of chromosome segregation (GO:0051983)3.34576344
59negative regulation of mitotic sister chromatid separation (GO:2000816)3.34403330
60negative regulation of mitotic sister chromatid segregation (GO:0033048)3.34403330
61negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.34403330
62negative regulation of sister chromatid segregation (GO:0033046)3.34403330
63regulation of mitotic metaphase/anaphase transition (GO:0030071)3.31042779
64regulation of centrosome cycle (GO:0046605)3.30920463
65spindle assembly checkpoint (GO:0071173)3.30763864
66mitotic spindle checkpoint (GO:0071174)3.30008679
67meiotic chromosome segregation (GO:0045132)3.29745029
68sister chromatid segregation (GO:0000819)3.29334275
69regulation of mitotic spindle organization (GO:0060236)3.27486457
70mitotic spindle assembly checkpoint (GO:0007094)3.26890983
71DNA geometric change (GO:0032392)3.25738159
72DNA duplex unwinding (GO:0032508)3.25732331
73DNA damage response, detection of DNA damage (GO:0042769)3.24747006
74negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.24649399
75regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.23582027
76establishment of integrated proviral latency (GO:0075713)3.22543858
77pore complex assembly (GO:0046931)3.21569465
78regulation of double-strand break repair via homologous recombination (GO:0010569)3.21489966
79exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.20648529
80mitotic sister chromatid cohesion (GO:0007064)3.20405917
81nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.19220341
82maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.17484087
83nucleotide-excision repair, DNA gap filling (GO:0006297)3.17368510
84rRNA processing (GO:0006364)3.16998143
85ribosomal large subunit biogenesis (GO:0042273)3.16836288
86regulation of mitotic sister chromatid separation (GO:0010965)3.15827068
87regulation of mitotic sister chromatid segregation (GO:0033047)3.15827068
88regulation of sister chromatid segregation (GO:0033045)3.15827068
89mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.15703920
90proteasome assembly (GO:0043248)3.13727860
91IMP metabolic process (GO:0046040)3.13179009
92protein localization to chromosome (GO:0034502)3.13153802
93DNA ligation (GO:0006266)3.12759870
94regulation of centriole replication (GO:0046599)3.10348239
95resolution of meiotic recombination intermediates (GO:0000712)3.09128610
96rRNA metabolic process (GO:0016072)3.08240259
97chromatin assembly or disassembly (GO:0006333)3.07604583
98ATP-dependent chromatin remodeling (GO:0043044)3.07355154
99spliceosomal snRNP assembly (GO:0000387)3.06920543
100rRNA modification (GO:0000154)3.04455531
101mismatch repair (GO:0006298)3.02810287
102regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.01484226
103DNA deamination (GO:0045006)3.00290219
104positive regulation of mitotic sister chromatid separation (GO:1901970)2.99023713
105positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.99023713
106positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.99023713
107protein complex biogenesis (GO:0070271)2.97723051
108mitochondrial respiratory chain complex assembly (GO:0033108)2.96972073
109negative regulation of DNA-dependent DNA replication (GO:2000104)2.96805532
110maturation of 5.8S rRNA (GO:0000460)2.95996762
111chromosome segregation (GO:0007059)2.94405092
112synapsis (GO:0007129)2.93703360
113telomere maintenance (GO:0000723)2.92219291
114negative regulation of DNA recombination (GO:0045910)2.92192875
115transcription-coupled nucleotide-excision repair (GO:0006283)2.91670665
116regulation of sister chromatid cohesion (GO:0007063)2.91597659
117telomere organization (GO:0032200)2.91357429
118DNA catabolic process, exonucleolytic (GO:0000738)2.89132739
119negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.88555810
120negative regulation of translation, ncRNA-mediated (GO:0040033)2.88555810
121regulation of translation, ncRNA-mediated (GO:0045974)2.88555810
122centriole replication (GO:0007099)2.85044296
123RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.84730845
124somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.84443946
125isotype switching (GO:0045190)2.84443946
126somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.84443946
127histone mRNA metabolic process (GO:0008334)2.83405046
128mitochondrial respiratory chain complex I assembly (GO:0032981)2.83232972
129NADH dehydrogenase complex assembly (GO:0010257)2.83232972
130mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.83232972
131protein neddylation (GO:0045116)2.81777513
132ATP synthesis coupled proton transport (GO:0015986)2.76873812
133energy coupled proton transport, down electrochemical gradient (GO:0015985)2.76873812
134regulation of meiosis I (GO:0060631)2.74799011
135postreplication repair (GO:0006301)2.73416807
136recombinational repair (GO:0000725)2.73050065
137double-strand break repair via homologous recombination (GO:0000724)2.69354559
138positive regulation of histone H3-K4 methylation (GO:0051571)2.67659539
139somatic diversification of immunoglobulins (GO:0016445)2.66929349
140chaperone-mediated protein transport (GO:0072321)2.66587103
141non-recombinational repair (GO:0000726)2.65669368
142double-strand break repair via nonhomologous end joining (GO:0006303)2.65669368
143respiratory chain complex IV assembly (GO:0008535)2.63862547
144somatic recombination of immunoglobulin gene segments (GO:0016447)2.62427191
145regulation of DNA endoreduplication (GO:0032875)2.61210641
146termination of RNA polymerase III transcription (GO:0006386)2.60410089
147transcription elongation from RNA polymerase III promoter (GO:0006385)2.60410089
148histone H2A acetylation (GO:0043968)2.58273459
149behavioral response to nicotine (GO:0035095)2.54561440
150somatic diversification of immune receptors (GO:0002200)2.54522123
151retinal cone cell development (GO:0046549)2.52661641
152regulation of mitochondrial translation (GO:0070129)2.52142874
153cullin deneddylation (GO:0010388)2.52051077
154protein-cofactor linkage (GO:0018065)2.51800790

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.54542969
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.47169723
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.18360577
4* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.07150152
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.23121604
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.04730650
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.86961827
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.86207087
9ZNF274_21170338_ChIP-Seq_K562_Hela2.85012344
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.83788690
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.77485793
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.66724569
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.63125792
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.61169624
15E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.54076883
16* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.50845622
17GABP_17652178_ChIP-ChIP_JURKAT_Human2.47029478
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.45545931
19* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.41895533
20* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.41500996
21FUS_26573619_Chip-Seq_HEK293_Human2.39349669
22EWS_26573619_Chip-Seq_HEK293_Human2.30865680
23EGR1_19374776_ChIP-ChIP_THP-1_Human2.26831368
24HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.26564219
25* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.25610952
26* VDR_23849224_ChIP-Seq_CD4+_Human2.20423869
27* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.17606636
28IGF1R_20145208_ChIP-Seq_DFB_Human2.14151188
29* XRN2_22483619_ChIP-Seq_HELA_Human2.13754074
30* E2F1_21310950_ChIP-Seq_MCF-7_Human2.08399195
31NANOG_18555785_ChIP-Seq_MESCs_Mouse2.08266472
32AR_21909140_ChIP-Seq_LNCAP_Human2.05044027
33VDR_22108803_ChIP-Seq_LS180_Human2.03956862
34* POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.01087493
35POU3F2_20337985_ChIP-ChIP_501MEL_Human1.99584750
36SALL1_21062744_ChIP-ChIP_HESCs_Human1.96655695
37* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.95683987
38* FOXP3_21729870_ChIP-Seq_TREG_Human1.88157948
39E2F1_18555785_ChIP-Seq_MESCs_Mouse1.88131621
40IRF1_19129219_ChIP-ChIP_H3396_Human1.83667888
41POU5F1_16153702_ChIP-ChIP_HESCs_Human1.83266728
42TAF15_26573619_Chip-Seq_HEK293_Human1.82589345
43NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.81248601
44SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.81076003
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.81032398
46* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.80472121
47PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73807938
48ZFP57_27257070_Chip-Seq_ESCs_Mouse1.71165641
49* TTF2_22483619_ChIP-Seq_HELA_Human1.70101186
50THAP11_20581084_ChIP-Seq_MESCs_Mouse1.69649981
51EZH2_22144423_ChIP-Seq_EOC_Human1.69294715
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.68623039
53ELK1_19687146_ChIP-ChIP_HELA_Human1.65278891
54GABP_19822575_ChIP-Seq_HepG2_Human1.64876666
55DCP1A_22483619_ChIP-Seq_HELA_Human1.64265797
56HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.64157749
57POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.64065432
58P300_19829295_ChIP-Seq_ESCs_Human1.63904867
59ELF1_17652178_ChIP-ChIP_JURKAT_Human1.63404116
60TP63_19390658_ChIP-ChIP_HaCaT_Human1.62192308
61CIITA_25753668_ChIP-Seq_RAJI_Human1.61755177
62FLI1_27457419_Chip-Seq_LIVER_Mouse1.59533419
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.54453969
64SOX2_16153702_ChIP-ChIP_HESCs_Human1.53837177
65* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.52736467
66* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.52070628
67SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.48506056
68* SOX2_18555785_ChIP-Seq_MESCs_Mouse1.46853995
69CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.44907834
70HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42456742
71RBPJ_22232070_ChIP-Seq_NCS_Mouse1.42364127
72* YY1_21170310_ChIP-Seq_MESCs_Mouse1.41493552
73* KDM5A_27292631_Chip-Seq_BREAST_Human1.41398214
74ZFX_18555785_ChIP-Seq_MESCs_Mouse1.41182094
75CTBP1_25329375_ChIP-Seq_LNCAP_Human1.39278299
76GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37667107
77GBX2_23144817_ChIP-Seq_PC3_Human1.37636091
78* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.37283703
79KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.36009533
80KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.36009533
81KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.36009533
82HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.35337150
83* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.32828054
84MYC_22102868_ChIP-Seq_BL_Human1.32781742
85* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.32190033
86NANOG_16153702_ChIP-ChIP_HESCs_Human1.30322296
87STAT3_1855785_ChIP-Seq_MESCs_Mouse1.29289155
88PADI4_21655091_ChIP-ChIP_MCF-7_Human1.24045443
89MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.22049054
90PCGF2_27294783_Chip-Seq_ESCs_Mouse1.19838938
91KLF4_18555785_ChIP-Seq_MESCs_Mouse1.19400719
92GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.18563260
93IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.17435233
94CBP_20019798_ChIP-Seq_JUKART_Human1.17435233
95SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.15087187
96SRF_21415370_ChIP-Seq_HL-1_Mouse1.12563221
97ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.12236528
98CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.11392401
99ERG_20887958_ChIP-Seq_HPC-7_Mouse1.11017694
100* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.09553880
101RNF2_27304074_Chip-Seq_NSC_Mouse1.09087721
102NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.08742764
103CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.07094011
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.07001486
105* TCF3_18692474_ChIP-Seq_MEFs_Mouse1.06979018
106* TP53_22573176_ChIP-Seq_HFKS_Human1.06780442
107FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.06634718
108SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.06195904
109* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.06032618
110PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.05941470
111* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05604292
112TFEB_21752829_ChIP-Seq_HELA_Human1.05276576
113NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.04447273
114* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.03936532
115UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03569938
116ESR1_15608294_ChIP-ChIP_MCF-7_Human1.03426508
117* NANOG_21062744_ChIP-ChIP_HESCs_Human1.02281194
118NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.01827610
119* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.00139345
120HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.99515066
121SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.98999291
122MYC_18940864_ChIP-ChIP_HL60_Human0.98429964
123EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.98347740
124NOTCH1_21737748_ChIP-Seq_TLL_Human0.98024801
125KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.98012868
126BMI1_23680149_ChIP-Seq_NPCS_Mouse0.97175402
127ER_23166858_ChIP-Seq_MCF-7_Human0.96887087
128* TCF3_18692474_ChIP-Seq_MESCs_Mouse0.96615730
129POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.95990814
130TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95990814
131KLF5_20875108_ChIP-Seq_MESCs_Mouse0.93804795
132AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91564238
133TOP2B_26459242_ChIP-Seq_MCF-7_Human0.91035167
134EZH2_27294783_Chip-Seq_NPCs_Mouse0.90514454
135* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90367373
136* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.89942746
137RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.89901458
138SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.87877455
139CBX2_27304074_Chip-Seq_ESCs_Mouse0.87503627
140PCGF2_27294783_Chip-Seq_NPCs_Mouse0.87286707
141* NANOG_19829295_ChIP-Seq_ESCs_Human0.87159209
142* SOX2_19829295_ChIP-Seq_ESCs_Human0.87159209
143* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.86395444
144* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.81344726
145* SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.80907357
146BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.80635320
147CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.80263543
148* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.79904229
149* SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.77894120

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.88108081
2MP0010094_abnormal_chromosome_stability5.22737275
3MP0003111_abnormal_nucleus_morphology4.92413601
4MP0008057_abnormal_DNA_replication4.52821012
5MP0004957_abnormal_blastocyst_morpholog4.48819084
6MP0003077_abnormal_cell_cycle4.17693332
7MP0008058_abnormal_DNA_repair3.92373162
8MP0008007_abnormal_cellular_replicative2.87757360
9MP0008877_abnormal_DNA_methylation2.76940920
10MP0008932_abnormal_embryonic_tissue2.59739884
11MP0003123_paternal_imprinting2.52781098
12MP0001730_embryonic_growth_arrest2.38435744
13MP0000350_abnormal_cell_proliferation2.34715299
14MP0002396_abnormal_hematopoietic_system2.32586471
15MP0001529_abnormal_vocalization2.26439272
16MP0003786_premature_aging2.25089091
17MP0010307_abnormal_tumor_latency2.13148783
18MP0010352_gastrointestinal_tract_polyps2.03724169
19MP0001672_abnormal_embryogenesis/_devel1.93616776
20MP0005380_embryogenesis_phenotype1.93616776
21MP0003718_maternal_effect1.88658797
22MP0003880_abnormal_central_pattern1.84878239
23MP0001188_hyperpigmentation1.84100850
24MP0005499_abnormal_olfactory_system1.81471707
25MP0005394_taste/olfaction_phenotype1.81471707
26MP0001697_abnormal_embryo_size1.78237077
27MP0006072_abnormal_retinal_apoptosis1.70991426
28MP0003122_maternal_imprinting1.70380473
29MP0006292_abnormal_olfactory_placode1.68895146
30MP0003984_embryonic_growth_retardation1.68773576
31MP0002085_abnormal_embryonic_tissue1.68368937
32MP0002088_abnormal_embryonic_growth/wei1.66710988
33MP0003121_genomic_imprinting1.65803520
34MP0003567_abnormal_fetal_cardiomyocyte1.64993153
35MP0002084_abnormal_developmental_patter1.63888916
36MP0002080_prenatal_lethality1.63251237
37MP0002234_abnormal_pharynx_morphology1.56380126
38MP0000490_abnormal_crypts_of1.55870371
39MP0002086_abnormal_extraembryonic_tissu1.55020627
40MP0002210_abnormal_sex_determination1.54108310
41MP0000631_abnormal_neuroendocrine_gland1.53248665
42MP0001293_anophthalmia1.50992346
43MP0004808_abnormal_hematopoietic_stem1.50914014
44MP0001984_abnormal_olfaction1.46506980
45MP0000313_abnormal_cell_death1.46476358
46MP0006276_abnormal_autonomic_nervous1.46406906
47MP0005084_abnormal_gallbladder_morpholo1.46218600
48MP0004197_abnormal_fetal_growth/weight/1.42181401
49MP0002751_abnormal_autonomic_nervous1.42036344
50MP0003315_abnormal_perineum_morphology1.38409796
51MP0000778_abnormal_nervous_system1.38098235
52MP0006035_abnormal_mitochondrial_morpho1.36243564
53MP0000049_abnormal_middle_ear1.33713709
54MP0001145_abnormal_male_reproductive1.33164141
55MP0003890_abnormal_embryonic-extraembry1.31759668
56MP0009697_abnormal_copulation1.29804237
57MP0005551_abnormal_eye_electrophysiolog1.29269572
58MP0002019_abnormal_tumor_incidence1.28502236
59MP0001929_abnormal_gametogenesis1.24457785
60MP0002233_abnormal_nose_morphology1.23688598
61MP0002736_abnormal_nociception_after1.22871272
62MP0002638_abnormal_pupillary_reflex1.20763121
63MP0001545_abnormal_hematopoietic_system1.20091531
64MP0005397_hematopoietic_system_phenotyp1.20091531
65MP0005253_abnormal_eye_physiology1.17236374
66MP0002160_abnormal_reproductive_system1.16646246
67MP0000653_abnormal_sex_gland1.13609789
68MP0000372_irregular_coat_pigmentation1.08074443
69MP0001968_abnormal_touch/_nociception1.07961184
70MP0000566_synostosis1.07030815
71MP0000703_abnormal_thymus_morphology1.05032556
72MP0005646_abnormal_pituitary_gland1.02769014
73MP0004133_heterotaxia1.01944434
74MP0002653_abnormal_ependyma_morphology1.00890087
75MP0005076_abnormal_cell_differentiation0.96832650
76MP0003941_abnormal_skin_development0.96825508
77MP0005389_reproductive_system_phenotype0.95568043
78MP0003119_abnormal_digestive_system0.94929647
79MP0003787_abnormal_imprinting0.94448952
80MP0009379_abnormal_foot_pigmentation0.93761306
81MP0005075_abnormal_melanosome_morpholog0.93592531
82MP0001485_abnormal_pinna_reflex0.93560683
83MP0009333_abnormal_splenocyte_physiolog0.91205000
84MP0001119_abnormal_female_reproductive0.90519278
85MP0004142_abnormal_muscle_tone0.90395255
86MP0002398_abnormal_bone_marrow0.90292391
87MP0005391_vision/eye_phenotype0.89326336
88MP0004147_increased_porphyrin_level0.89104166
89MP0003937_abnormal_limbs/digits/tail_de0.88850777
90MP0002697_abnormal_eye_size0.88516835
91MP0000427_abnormal_hair_cycle0.88437140
92MP0000647_abnormal_sebaceous_gland0.87965281
93MP0009703_decreased_birth_body0.87659804
94MP0002837_dystrophic_cardiac_calcinosis0.87321435
95MP0000569_abnormal_digit_pigmentation0.87264199
96MP0002752_abnormal_somatic_nervous0.87033003
97MP0003136_yellow_coat_color0.85041382
98MP0002722_abnormal_immune_system0.84881177
99MP0005195_abnormal_posterior_eye0.84408778
100MP0009672_abnormal_birth_weight0.84390544
101MP0005645_abnormal_hypothalamus_physiol0.83172228
102MP0002272_abnormal_nervous_system0.82371273
103MP0002184_abnormal_innervation0.81362834
104MP0002282_abnormal_trachea_morphology0.81110414
105MP0005384_cellular_phenotype0.80951617
106MP0002557_abnormal_social/conspecific_i0.80577606
107MP0003763_abnormal_thymus_physiology0.79753564
108MP0001324_abnormal_eye_pigmentation0.78452831
109MP0000689_abnormal_spleen_morphology0.78345147
110MP0002095_abnormal_skin_pigmentation0.78242456
111MP0000358_abnormal_cell_content/0.78193345
112MP0001486_abnormal_startle_reflex0.78129776
113MP0001286_abnormal_eye_development0.77159654
114MP0003806_abnormal_nucleotide_metabolis0.77107789
115MP0005187_abnormal_penis_morphology0.76865052
116MP0002092_abnormal_eye_morphology0.76181450
117MP0000537_abnormal_urethra_morphology0.74984103
118MP0003698_abnormal_male_reproductive0.74607597
119MP0005377_hearing/vestibular/ear_phenot0.74393815
120MP0003878_abnormal_ear_physiology0.74393815
121MP0005621_abnormal_cell_physiology0.74109723
122MP0003755_abnormal_palate_morphology0.74033426
123MP0008260_abnormal_autophagy0.73045204
124MP0002938_white_spotting0.72737769
125MP0003938_abnormal_ear_development0.72583949
126MP0005174_abnormal_tail_pigmentation0.72443079
127MP0004742_abnormal_vestibular_system0.71854115
128MP0010030_abnormal_orbit_morphology0.71812561
129MP0009046_muscle_twitch0.71368220
130MP0002254_reproductive_system_inflammat0.71356701
131MP0001177_atelectasis0.69365148
132MP0009278_abnormal_bone_marrow0.67038590
133* MP0002111_abnormal_tail_morphology0.64696951
134MP0008995_early_reproductive_senescence0.64516787
135* MP0003861_abnormal_nervous_system0.64338160
136MP0002429_abnormal_blood_cell0.63650284
137MP0003221_abnormal_cardiomyocyte_apopto0.63357739
138MP0002102_abnormal_ear_morphology0.61371160
139MP0004264_abnormal_extraembryonic_tissu0.60952617
140MP0002075_abnormal_coat/hair_pigmentati0.60847667
141* MP0002161_abnormal_fertility/fecundity0.60042620
142MP0003699_abnormal_female_reproductive0.58258001
143MP0001919_abnormal_reproductive_system0.57068799
144MP0000516_abnormal_urinary_system0.56272903
145MP0005367_renal/urinary_system_phenotyp0.56272903
146MP0003936_abnormal_reproductive_system0.56070393
147MP0008789_abnormal_olfactory_epithelium0.55175792
148MP0000477_abnormal_intestine_morphology0.55164428
149MP0001849_ear_inflammation0.54864487
150MP0000428_abnormal_craniofacial_morphol0.52635862
151MP0000716_abnormal_immune_system0.52022499

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.34817127
2Chromsome breakage (HP:0040012)4.78790861
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.68906852
4Breast hypoplasia (HP:0003187)4.12409798
5Ependymoma (HP:0002888)4.00722579
6Abnormality of chromosome stability (HP:0003220)3.71827249
7Patellar aplasia (HP:0006443)3.64426722
8Medulloblastoma (HP:0002885)3.61602250
9Meckel diverticulum (HP:0002245)3.61537171
10Abnormality of the labia minora (HP:0012880)3.56970699
11Reticulocytopenia (HP:0001896)3.54814883
12Abnormality of the preputium (HP:0100587)3.52113272
13Agnosia (HP:0010524)3.45196252
14Abnormality of the ileum (HP:0001549)3.42779748
15Aplasia/Hypoplasia of the patella (HP:0006498)3.42582511
16Colon cancer (HP:0003003)3.36768817
17Impulsivity (HP:0100710)3.33928875
18Aplasia/Hypoplasia of the uvula (HP:0010293)3.31084795
19Supernumerary spleens (HP:0009799)3.22230436
20Carpal bone hypoplasia (HP:0001498)3.18848208
21Absent radius (HP:0003974)3.12229641
22Oral leukoplakia (HP:0002745)3.04635582
23Myelodysplasia (HP:0002863)3.03673715
24Aplasia involving forearm bones (HP:0009822)2.90950633
25Absent forearm bone (HP:0003953)2.90950633
26Small intestinal stenosis (HP:0012848)2.90157421
27Duodenal stenosis (HP:0100867)2.90157421
28Pancreatic cysts (HP:0001737)2.89890634
29Pancreatic fibrosis (HP:0100732)2.89695343
30Rough bone trabeculation (HP:0100670)2.86632555
31Absent thumb (HP:0009777)2.81276396
32Degeneration of anterior horn cells (HP:0002398)2.79990642
33Abnormality of the anterior horn cell (HP:0006802)2.79990642
34Bone marrow hypocellularity (HP:0005528)2.79748627
35Selective tooth agenesis (HP:0001592)2.79230651
36Rhabdomyosarcoma (HP:0002859)2.75389645
37Aplastic anemia (HP:0001915)2.75332547
38Hyperglycinemia (HP:0002154)2.66668090
39True hermaphroditism (HP:0010459)2.64858063
40Abnormality of cells of the erythroid lineage (HP:0012130)2.61891696
41Glioma (HP:0009733)2.60555086
42Astrocytoma (HP:0009592)2.58893462
43Abnormality of the astrocytes (HP:0100707)2.58893462
44Abnormality of midbrain morphology (HP:0002418)2.55096159
45Molar tooth sign on MRI (HP:0002419)2.55096159
46Cerebral hypomyelination (HP:0006808)2.54164403
47Volvulus (HP:0002580)2.53002641
48Acute necrotizing encephalopathy (HP:0006965)2.51650450
49Neoplasm of the oral cavity (HP:0100649)2.51474550
50Nephronophthisis (HP:0000090)2.49642454
51Sloping forehead (HP:0000340)2.49445731
52Medial flaring of the eyebrow (HP:0010747)2.49325943
53Neoplasm of the pancreas (HP:0002894)2.48748402
54Septo-optic dysplasia (HP:0100842)2.48609161
55Abnormal number of erythroid precursors (HP:0012131)2.46600328
56Ectopic kidney (HP:0000086)2.46059883
57Methylmalonic acidemia (HP:0002912)2.42258299
58Abnormality of the duodenum (HP:0002246)2.37190335
59Premature graying of hair (HP:0002216)2.34410295
60Acute encephalopathy (HP:0006846)2.34163582
61Abnormality of the carotid arteries (HP:0005344)2.33233073
62Abnormal number of incisors (HP:0011064)2.30332091
63Duplicated collecting system (HP:0000081)2.30295835
64Horseshoe kidney (HP:0000085)2.28562999
65Clubbing of toes (HP:0100760)2.27462482
66Abnormal mitochondria in muscle tissue (HP:0008316)2.25742844
67Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.25715844
68Tracheoesophageal fistula (HP:0002575)2.25196485
69Amaurosis fugax (HP:0100576)2.23810799
70Basal cell carcinoma (HP:0002671)2.23491202
71Lipid accumulation in hepatocytes (HP:0006561)2.20211461
72Increased hepatocellular lipid droplets (HP:0006565)2.20141045
73Intestinal atresia (HP:0011100)2.20066209
74Cellular immunodeficiency (HP:0005374)2.19793769
75Biliary tract neoplasm (HP:0100574)2.18507064
76Abnormal lung lobation (HP:0002101)2.18350535
77Gait imbalance (HP:0002141)2.17375912
78Congenital primary aphakia (HP:0007707)2.16653932
79Aplasia/Hypoplasia of the sternum (HP:0006714)2.16543284
80Proximal placement of thumb (HP:0009623)2.16292037
81Nephroblastoma (Wilms tumor) (HP:0002667)2.14778332
82Triphalangeal thumb (HP:0001199)2.14008539
83Progressive macrocephaly (HP:0004481)2.13146608
84Short thumb (HP:0009778)2.12809524
85Prominent nose (HP:0000448)2.12644950
86Facial hemangioma (HP:0000329)2.12322751
87Mitochondrial inheritance (HP:0001427)2.10808951
88Increased nuchal translucency (HP:0010880)2.09959020
89Nephrogenic diabetes insipidus (HP:0009806)2.08686497
90Genital tract atresia (HP:0001827)2.08637246
91Cafe-au-lait spot (HP:0000957)2.07832181
92Neoplasm of striated muscle (HP:0009728)2.07576891
93Abnormality of DNA repair (HP:0003254)2.07537950
94Pallor (HP:0000980)2.07102263
95Anencephaly (HP:0002323)2.06707801
96Increased CSF lactate (HP:0002490)2.05693796
97Macrocytic anemia (HP:0001972)2.04114884
9811 pairs of ribs (HP:0000878)2.03654182
99Abnormality of the renal collecting system (HP:0004742)2.03278656
100Abnormal trabecular bone morphology (HP:0100671)2.02864649
101Atresia of the external auditory canal (HP:0000413)2.01873928
102Abnormality of the renal medulla (HP:0100957)2.01014069
103Vaginal atresia (HP:0000148)2.00494240
104Shawl scrotum (HP:0000049)1.99711367
105Premature ovarian failure (HP:0008209)1.99430759
106Hyperglycinuria (HP:0003108)1.98901571
107Deviation of the thumb (HP:0009603)1.97339167
108Embryonal renal neoplasm (HP:0011794)1.95508510
109Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.95324457
110Optic nerve hypoplasia (HP:0000609)1.94980551
111Lymphoma (HP:0002665)1.94626661
112Sclerocornea (HP:0000647)1.93903611
113Aplasia/hypoplasia of the humerus (HP:0006507)1.92852273
114Abnormality of abdominal situs (HP:0011620)1.92105749
115Abdominal situs inversus (HP:0003363)1.92105749
116Abnormality of glycine metabolism (HP:0010895)1.91160546
117Abnormality of serine family amino acid metabolism (HP:0010894)1.91160546
118Abnormal biliary tract physiology (HP:0012439)1.91024413
119Bile duct proliferation (HP:0001408)1.91024413
120Neoplasm of the colon (HP:0100273)1.90626961
121Aplasia/Hypoplasia of the tongue (HP:0010295)1.90200207
122Congenital stationary night blindness (HP:0007642)1.88815211
123Bilateral microphthalmos (HP:0007633)1.87924666
124Abnormality of serum amino acid levels (HP:0003112)1.87242694
125Preaxial hand polydactyly (HP:0001177)1.86801021
126Postaxial foot polydactyly (HP:0001830)1.85867131
127Renal cortical cysts (HP:0000803)1.85790552
128Absent septum pellucidum (HP:0001331)1.84296773
129Cleft eyelid (HP:0000625)1.84213076
130Pendular nystagmus (HP:0012043)1.83574241
1313-Methylglutaconic aciduria (HP:0003535)1.81251510
132Atrophy/Degeneration involving motor neurons (HP:0007373)1.81122478
133Oligodactyly (hands) (HP:0001180)1.79341361
134Short tibia (HP:0005736)1.78775070
135Aplasia/Hypoplasia of the tibia (HP:0005772)1.78144484
136Squamous cell carcinoma (HP:0002860)1.78078349
137Anophthalmia (HP:0000528)1.77892601
138Ureteral duplication (HP:0000073)1.77464024
139Stenosis of the external auditory canal (HP:0000402)1.77246535
140Dandy-Walker malformation (HP:0001305)1.77000612
141Abnormal spermatogenesis (HP:0008669)1.76438895
142Hypoplasia of the radius (HP:0002984)1.75958304
143Methylmalonic aciduria (HP:0012120)1.75424657
144Optic disc pallor (HP:0000543)1.73708123
145Acute lymphatic leukemia (HP:0006721)1.73149820
146Abnormality of the septum pellucidum (HP:0007375)1.72828680
147Abnormality of the renal cortex (HP:0011035)1.72777733
148Growth hormone deficiency (HP:0000824)1.72773936
149Abnormal hair whorl (HP:0010721)1.72503146
150Bifid tongue (HP:0010297)1.72161351
151Asplenia (HP:0001746)1.72159891
152Chronic hepatic failure (HP:0100626)1.71801541
153Spinal muscular atrophy (HP:0007269)1.70785510
154Lissencephaly (HP:0001339)1.70727990
155Arteriovenous malformation (HP:0100026)1.69815664
156Pelvic girdle muscle weakness (HP:0003749)1.69481636
157Aplasia/Hypoplasia of the earlobes (HP:0009906)1.69263327
158Hepatocellular necrosis (HP:0001404)1.68839030
159Acute myeloid leukemia (HP:0004808)1.68822200
160Astigmatism (HP:0000483)1.67826170
161Abolished electroretinogram (ERG) (HP:0000550)1.67804728
162Small hand (HP:0200055)1.67016938
163Cerebral edema (HP:0002181)1.66373848
164Postaxial hand polydactyly (HP:0001162)1.66285740

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE15.28777492
2BUB14.57631983
3CDC73.89595220
4SRPK13.25100904
5NEK22.90387010
6WNK32.78408420
7MAP4K22.66784718
8TTK2.65435827
9TSSK62.63990589
10EPHA22.61153911
11BMPR1B2.58456151
12EIF2AK12.57330487
13BRSK22.50839658
14PLK42.45827620
15PNCK2.42974909
16TNIK2.31675511
17NEK12.30951440
18VRK22.19824599
19PLK12.16737592
20MKNK12.16709282
21STK162.15669678
22ACVR1B2.14567712
23TRIM282.08975287
24MKNK21.96643167
25INSRR1.94720893
26PLK31.93967001
27MAP3K41.91823326
28RPS6KB21.90048540
29CDK121.83470207
30EIF2AK31.82159387
31DYRK31.81451293
32ATR1.79370200
33TAF11.77134185
34CHEK21.68734852
35VRK11.68173858
36AURKB1.63545404
37CASK1.61120637
38CDK71.60880210
39AKT31.58793672
40PASK1.56305152
41ZAK1.52469488
42FRK1.46499597
43TLK11.45897187
44BRD41.44077136
45BRSK11.41119386
46MAPK131.37871989
47CHEK11.34931102
48CDK41.26065105
49BCR1.24666580
50AURKA1.16939425
51PBK1.15055232
52NME21.14976822
53MAP2K71.14808881
54CDK191.13652673
55EPHA41.13395288
56CSNK1G21.10764610
57STK41.09903202
58GRK11.04376946
59NME11.02102561
60ATM1.01866074
61MAP3K80.99761692
62CCNB10.97778905
63MARK10.97467876
64CDK20.97236001
65ADRBK20.93095209
66BCKDK0.89341329
67RPS6KA40.88922265
68ALK0.88517488
69TGFBR10.87292771
70PINK10.87236199
71MST40.87114129
72TESK20.83945262
73OXSR10.83938673
74CSNK1A1L0.81701926
75PIM10.80916731
76PLK20.79099056
77SCYL20.75935510
78EEF2K0.75626544
79EIF2AK20.74269525
80CDK10.72837750
81PRKCI0.72276597
82PDK40.69579938
83PDK30.69579938
84CSNK2A20.69240157
85PAK40.68754157
86MELK0.67164347
87WNK40.65843112
88STK390.65292299
89PRKCG0.64809128
90BRAF0.62582181
91FLT30.62525453
92MINK10.61415779
93STK100.59710917
94CSNK2A10.59041241
95CDK60.58852846
96FGFR20.57129613
97STK30.54631753
98DYRK1A0.53925648
99PAK10.49665286
100EPHB20.49489201
101STK38L0.48869061
102YES10.47224903
103CSNK1E0.47090365
104PRKCE0.46886103
105RPS6KA50.43518809
106NLK0.42507258
107PDK20.42484397
108PRKDC0.41041810
109TIE10.37376330
110DYRK20.35607805
111CDK80.34790547
112CSNK1A10.34512666
113MAPK140.33185824
114PAK30.32747339
115MAPKAPK50.32070400
116CSNK1D0.31129951
117CDK30.30863325
118PKN10.30692691
119CLK10.29814790
120PRKACB0.29070471
121AKT20.28466002
122TAOK20.28169296
123GSK3B0.26480070
124ERBB30.25484265
125DAPK10.24233971
126MTOR0.23897887
127CSNK1G30.23501969
128MARK30.22727547
129RAF10.22391369
130MAP2K30.21832294
131RPS6KB10.20901274
132MAP4K10.19868312
133NUAK10.18669505
134TEC0.17901064
135AKT10.17272359
136MAPK10.16480772
137MAP3K60.16101351
138BTK0.15939389
139CSNK1G10.14524011
140MAPK100.13741514
141MAP3K50.12430841
142FGFR10.09261304
143MAPK90.09114039

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.69306250
2Mismatch repair_Homo sapiens_hsa034304.37961777
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.13993013
4Spliceosome_Homo sapiens_hsa030403.42615259
5RNA transport_Homo sapiens_hsa030133.42541982
6RNA polymerase_Homo sapiens_hsa030203.38788259
7Homologous recombination_Homo sapiens_hsa034403.11340903
8Base excision repair_Homo sapiens_hsa034103.04394574
9Cell cycle_Homo sapiens_hsa041102.96592890
10Nucleotide excision repair_Homo sapiens_hsa034202.90446932
11Proteasome_Homo sapiens_hsa030502.89962499
12Ribosome_Homo sapiens_hsa030102.77215636
13Fanconi anemia pathway_Homo sapiens_hsa034602.72344791
14Non-homologous end-joining_Homo sapiens_hsa034502.61623625
15Protein export_Homo sapiens_hsa030602.59230208
16Oxidative phosphorylation_Homo sapiens_hsa001902.51995433
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.44777186
18Pyrimidine metabolism_Homo sapiens_hsa002402.42685600
19One carbon pool by folate_Homo sapiens_hsa006702.41363564
20Basal transcription factors_Homo sapiens_hsa030222.33644241
21Parkinsons disease_Homo sapiens_hsa050122.27923640
22mRNA surveillance pathway_Homo sapiens_hsa030152.07025640
23RNA degradation_Homo sapiens_hsa030182.01786707
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.95074713
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.78297576
26Propanoate metabolism_Homo sapiens_hsa006401.76290330
27p53 signaling pathway_Homo sapiens_hsa041151.69899045
28Phototransduction_Homo sapiens_hsa047441.67385678
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.59916388
30Purine metabolism_Homo sapiens_hsa002301.38774178
31Vitamin B6 metabolism_Homo sapiens_hsa007501.34746793
32Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.34347772
33Oocyte meiosis_Homo sapiens_hsa041141.31164337
34Epstein-Barr virus infection_Homo sapiens_hsa051691.29986350
35Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.28134729
36Nicotine addiction_Homo sapiens_hsa050331.27574765
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.26238903
38Systemic lupus erythematosus_Homo sapiens_hsa053221.25656682
39Alzheimers disease_Homo sapiens_hsa050101.22092587
40Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.15336902
41Butanoate metabolism_Homo sapiens_hsa006501.12182538
42Steroid biosynthesis_Homo sapiens_hsa001001.04679323
43Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.03543081
44Herpes simplex infection_Homo sapiens_hsa051680.97956412
45Viral carcinogenesis_Homo sapiens_hsa052030.97296634
46Fatty acid elongation_Homo sapiens_hsa000620.93197220
47Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.92056372
48Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.91183643
49Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.88357110
50Cardiac muscle contraction_Homo sapiens_hsa042600.88050322
51Antigen processing and presentation_Homo sapiens_hsa046120.87165409
52Pyruvate metabolism_Homo sapiens_hsa006200.83018101
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82085874
54Peroxisome_Homo sapiens_hsa041460.79596513
55Folate biosynthesis_Homo sapiens_hsa007900.72403178
56Pentose phosphate pathway_Homo sapiens_hsa000300.72279504
57Taste transduction_Homo sapiens_hsa047420.71037389
58HTLV-I infection_Homo sapiens_hsa051660.70523495
59Cysteine and methionine metabolism_Homo sapiens_hsa002700.69723410
60Linoleic acid metabolism_Homo sapiens_hsa005910.68089113
61Olfactory transduction_Homo sapiens_hsa047400.67156925
62MicroRNAs in cancer_Homo sapiens_hsa052060.67040538
63Thyroid cancer_Homo sapiens_hsa052160.65517476
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.65220354
65Drug metabolism - other enzymes_Homo sapiens_hsa009830.64812939
66Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64451215
67Regulation of autophagy_Homo sapiens_hsa041400.64347801
68Transcriptional misregulation in cancer_Homo sapiens_hsa052020.62290728
69Selenocompound metabolism_Homo sapiens_hsa004500.62152895
70Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.60168097
71Ether lipid metabolism_Homo sapiens_hsa005650.59261374
72Tryptophan metabolism_Homo sapiens_hsa003800.57602234
73Primary immunodeficiency_Homo sapiens_hsa053400.54508971
74Caffeine metabolism_Homo sapiens_hsa002320.54428244
75Alcoholism_Homo sapiens_hsa050340.51126209
76Nitrogen metabolism_Homo sapiens_hsa009100.50874064
77Biosynthesis of amino acids_Homo sapiens_hsa012300.49966529
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.49290239
79Colorectal cancer_Homo sapiens_hsa052100.49085626
80Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.46556432
81Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.45698548
82Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43891872
83Small cell lung cancer_Homo sapiens_hsa052220.43484924
84Pentose and glucuronate interconversions_Homo sapiens_hsa000400.41422899
85Retinol metabolism_Homo sapiens_hsa008300.39817497
86Legionellosis_Homo sapiens_hsa051340.39676434
87Hippo signaling pathway_Homo sapiens_hsa043900.39626329
88Maturity onset diabetes of the young_Homo sapiens_hsa049500.39472721
89NOD-like receptor signaling pathway_Homo sapiens_hsa046210.37758347
90mTOR signaling pathway_Homo sapiens_hsa041500.36509463
91Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36421949
92TGF-beta signaling pathway_Homo sapiens_hsa043500.36369491
932-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.34168124
94Vitamin digestion and absorption_Homo sapiens_hsa049770.34039974
95Fructose and mannose metabolism_Homo sapiens_hsa000510.33877369
96GABAergic synapse_Homo sapiens_hsa047270.33643704
97NF-kappa B signaling pathway_Homo sapiens_hsa040640.33510106
98Basal cell carcinoma_Homo sapiens_hsa052170.32565509
99Notch signaling pathway_Homo sapiens_hsa043300.31218452
100Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.30979356
101Apoptosis_Homo sapiens_hsa042100.30897513
102Steroid hormone biosynthesis_Homo sapiens_hsa001400.30162265
103Serotonergic synapse_Homo sapiens_hsa047260.29411626
104Measles_Homo sapiens_hsa051620.29144037
105Morphine addiction_Homo sapiens_hsa050320.28937572
106Fatty acid metabolism_Homo sapiens_hsa012120.28210283
107Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.27370114
108Hepatitis B_Homo sapiens_hsa051610.27288540
109Collecting duct acid secretion_Homo sapiens_hsa049660.27042516
110Cyanoamino acid metabolism_Homo sapiens_hsa004600.26995790
111Renin-angiotensin system_Homo sapiens_hsa046140.26605385
112Circadian rhythm_Homo sapiens_hsa047100.26550203
113Hedgehog signaling pathway_Homo sapiens_hsa043400.25627782
114Pathways in cancer_Homo sapiens_hsa052000.25197199
115Influenza A_Homo sapiens_hsa051640.24210208
116Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.23644472
117Chemical carcinogenesis_Homo sapiens_hsa052040.23529537
118FoxO signaling pathway_Homo sapiens_hsa040680.22148259
119Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.22144577
120Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.21737352
121Lysine degradation_Homo sapiens_hsa003100.21369164
122HIF-1 signaling pathway_Homo sapiens_hsa040660.20348028
123Shigellosis_Homo sapiens_hsa051310.20343379
124Intestinal immune network for IgA production_Homo sapiens_hsa046720.18656618
125Huntingtons disease_Homo sapiens_hsa050160.18568712
126Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.18270990
127Wnt signaling pathway_Homo sapiens_hsa043100.18078291
128Prostate cancer_Homo sapiens_hsa052150.18033204
129Sulfur relay system_Homo sapiens_hsa041220.18019588
130RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.17739551
131Glutathione metabolism_Homo sapiens_hsa004800.17299930
132Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.16893429
133Hematopoietic cell lineage_Homo sapiens_hsa046400.16065159
134N-Glycan biosynthesis_Homo sapiens_hsa005100.14560415
135Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.13959178
136Thyroid hormone signaling pathway_Homo sapiens_hsa049190.13634652
137Chronic myeloid leukemia_Homo sapiens_hsa052200.13095499
138Acute myeloid leukemia_Homo sapiens_hsa052210.12973086
139Tight junction_Homo sapiens_hsa045300.12524988
140Adherens junction_Homo sapiens_hsa045200.11549804
141Non-small cell lung cancer_Homo sapiens_hsa052230.11075019
142Central carbon metabolism in cancer_Homo sapiens_hsa052300.09100933
143Galactose metabolism_Homo sapiens_hsa000520.09058048
144Carbon metabolism_Homo sapiens_hsa012000.08042581
145Metabolic pathways_Homo sapiens_hsa011000.07168012
146Arachidonic acid metabolism_Homo sapiens_hsa005900.07036477
147Asthma_Homo sapiens_hsa053100.06154463
148Glycerophospholipid metabolism_Homo sapiens_hsa005640.05743061
149Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.04898626
150Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.04377760
151Inositol phosphate metabolism_Homo sapiens_hsa005620.03522996
152Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.02207383

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