MTFR2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.91754439
2protein localization to chromosome, centromeric region (GO:0071459)5.13658214
3mitotic metaphase plate congression (GO:0007080)5.01962039
4kinetochore organization (GO:0051383)4.99475436
5mitotic chromosome condensation (GO:0007076)4.99307777
6mitotic sister chromatid segregation (GO:0000070)4.96482812
7attachment of spindle microtubules to kinetochore (GO:0008608)4.72930635
8kinetochore assembly (GO:0051382)4.47473714
9metaphase plate congression (GO:0051310)4.46942183
10DNA replication checkpoint (GO:0000076)4.45994060
11CENP-A containing nucleosome assembly (GO:0034080)4.44249509
12sister chromatid segregation (GO:0000819)4.43797452
13meiotic chromosome segregation (GO:0045132)4.43567218
14chromatin remodeling at centromere (GO:0031055)4.39698447
15proteasome assembly (GO:0043248)4.33911212
16DNA strand elongation involved in DNA replication (GO:0006271)4.33460300
17DNA replication initiation (GO:0006270)4.23374067
18establishment of chromosome localization (GO:0051303)4.23202904
19DNA strand elongation (GO:0022616)4.19553567
20protein K6-linked ubiquitination (GO:0085020)4.10062325
21telomere maintenance via semi-conservative replication (GO:0032201)4.09879402
22mitotic nuclear envelope disassembly (GO:0007077)4.04045299
23DNA replication-independent nucleosome organization (GO:0034724)4.00876655
24DNA replication-independent nucleosome assembly (GO:0006336)4.00876655
25DNA ligation (GO:0006266)3.93615908
26regulation of spindle organization (GO:0090224)3.92404143
27protein localization to chromosome (GO:0034502)3.91958772
28telomere maintenance via recombination (GO:0000722)3.90634000
29anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.90406045
30DNA unwinding involved in DNA replication (GO:0006268)3.86282066
31positive regulation of chromosome segregation (GO:0051984)3.82982203
32mitotic recombination (GO:0006312)3.80083027
33regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.78949926
34establishment of integrated proviral latency (GO:0075713)3.74754870
35chromosome segregation (GO:0007059)3.74708072
36regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.72277794
37nuclear envelope disassembly (GO:0051081)3.70403991
38membrane disassembly (GO:0030397)3.70403991
39negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.70174149
40histone exchange (GO:0043486)3.68391190
41mitotic sister chromatid cohesion (GO:0007064)3.63134899
42positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.59842293
43positive regulation of mitotic sister chromatid separation (GO:1901970)3.59842293
44positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.59842293
45nuclear pore organization (GO:0006999)3.59606640
46nuclear pore complex assembly (GO:0051292)3.59387656
47spindle checkpoint (GO:0031577)3.58914991
48ribosome assembly (GO:0042255)3.57268485
49regulation of centriole replication (GO:0046599)3.54509976
50mitotic G2/M transition checkpoint (GO:0044818)3.53424304
51regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.52888120
52regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.52875724
53negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.52654327
54regulation of chromosome segregation (GO:0051983)3.49835502
55positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.46852449
56regulation of mitotic spindle organization (GO:0060236)3.42244072
57negative regulation of ligase activity (GO:0051352)3.42125987
58negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.42125987
59regulation of mitotic metaphase/anaphase transition (GO:0030071)3.41728167
60negative regulation of chromosome segregation (GO:0051985)3.41402216
61telomere maintenance via telomere lengthening (GO:0010833)3.40472683
62negative regulation of sister chromatid segregation (GO:0033046)3.38105485
63negative regulation of mitotic sister chromatid separation (GO:2000816)3.38105485
64negative regulation of mitotic sister chromatid segregation (GO:0033048)3.38105485
65negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.38105485
66maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.37041272
67spindle assembly checkpoint (GO:0071173)3.36769432
68DNA packaging (GO:0006323)3.32228064
69cell cycle G1/S phase transition (GO:0044843)3.26876276
70G1/S transition of mitotic cell cycle (GO:0000082)3.26876276
71regulation of mitotic sister chromatid separation (GO:0010965)3.26446505
72regulation of mitotic sister chromatid segregation (GO:0033047)3.26446505
73regulation of sister chromatid segregation (GO:0033045)3.26446505
74chromatin assembly or disassembly (GO:0006333)3.25991837
75replication fork processing (GO:0031297)3.25307371
76mitotic spindle assembly checkpoint (GO:0007094)3.24237402
77piRNA metabolic process (GO:0034587)3.23198738
78mitotic spindle checkpoint (GO:0071174)3.23147471
79purine nucleobase biosynthetic process (GO:0009113)3.22378808
80regulation of DNA endoreduplication (GO:0032875)3.20804616
81nucleotide-excision repair, DNA gap filling (GO:0006297)3.20678028
82regulation of double-strand break repair via homologous recombination (GO:0010569)3.19902812
83IMP biosynthetic process (GO:0006188)3.17159618
84folic acid-containing compound biosynthetic process (GO:0009396)3.14116921
85IMP metabolic process (GO:0046040)3.12373393
86DNA catabolic process, exonucleolytic (GO:0000738)3.10987447
87DNA topological change (GO:0006265)3.10565957
88double-strand break repair via nonhomologous end joining (GO:0006303)3.09153813
89non-recombinational repair (GO:0000726)3.09153813
90formation of translation preinitiation complex (GO:0001731)3.09085373
91regulation of sister chromatid cohesion (GO:0007063)3.08735661
92synapsis (GO:0007129)3.08408152
93negative regulation of mitosis (GO:0045839)3.07880226
94DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.06788116
95positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.06546499
96microtubule depolymerization (GO:0007019)3.05266512
97regulation of nuclear cell cycle DNA replication (GO:0033262)3.04579617
98deoxyribonucleotide biosynthetic process (GO:0009263)3.03525256
99telomere maintenance (GO:0000723)3.01434259
100DNA replication-dependent nucleosome assembly (GO:0006335)3.01269632
101DNA replication-dependent nucleosome organization (GO:0034723)3.01269632
102DNA double-strand break processing (GO:0000729)3.00776225
103mitotic G2 DNA damage checkpoint (GO:0007095)3.00648482
104DNA geometric change (GO:0032392)2.99782298
105DNA duplex unwinding (GO:0032508)2.99086590
106regulation of centrosome cycle (GO:0046605)2.98006266
107telomere organization (GO:0032200)2.97173431
108maturation of 5.8S rRNA (GO:0000460)2.96856812
109chromosome condensation (GO:0030261)2.96117419
110DNA damage response, signal transduction resulting in transcription (GO:0042772)2.95858130
111regulation of exit from mitosis (GO:0007096)2.95200479
112mismatch repair (GO:0006298)2.95133959
113nuclear envelope organization (GO:0006998)2.90154718
114ATP-dependent chromatin remodeling (GO:0043044)2.87930246
115DNA conformation change (GO:0071103)2.86400700
116translesion synthesis (GO:0019985)2.82996710
117mitotic cell cycle (GO:0000278)2.81746707
118DNA synthesis involved in DNA repair (GO:0000731)2.81376216
119pore complex assembly (GO:0046931)2.81336660
120regulation of histone H3-K9 methylation (GO:0051570)2.79714507
121nucleobase biosynthetic process (GO:0046112)2.76360912
122DNA strand renaturation (GO:0000733)2.76267334
123regulation of telomere maintenance via telomerase (GO:0032210)2.75529920
124chromosome organization (GO:0051276)2.73933613
125histone H2A monoubiquitination (GO:0035518)2.73141206
126negative regulation of DNA-dependent DNA replication (GO:2000104)2.72131473
127sister chromatid cohesion (GO:0007062)2.71386274

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human6.41572264
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.61574036
3* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.23625773
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.13572605
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.59816714
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.52312114
7AR_21909140_ChIP-Seq_LNCAP_Human2.46612695
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.43318392
9E2F1_21310950_ChIP-Seq_MCF-7_Human2.43128265
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.42352504
11MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.34964971
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.21647017
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.21356782
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.06237862
15MYC_19079543_ChIP-ChIP_MESCs_Mouse2.05195014
16E2F7_22180533_ChIP-Seq_HELA_Human11.2256059
17NELFA_20434984_ChIP-Seq_ESCs_Mouse1.98386115
18KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.97730086
19SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.97153591
20GABP_17652178_ChIP-ChIP_JURKAT_Human1.94897151
21MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.87655491
22VDR_23849224_ChIP-Seq_CD4+_Human1.80822258
23JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.75552676
24ETS1_20019798_ChIP-Seq_JURKAT_Human1.74423065
25PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.72242755
26CREB1_15753290_ChIP-ChIP_HEK293T_Human1.72131602
27XRN2_22483619_ChIP-Seq_HELA_Human1.68659335
28MYCN_18555785_ChIP-Seq_MESCs_Mouse1.68648980
29FOXP3_21729870_ChIP-Seq_TREG_Human1.68214288
30TP63_19390658_ChIP-ChIP_HaCaT_Human1.66414513
31MYC_22102868_ChIP-Seq_BL_Human1.65261088
32ELF1_17652178_ChIP-ChIP_JURKAT_Human1.64617653
33HOXB4_20404135_ChIP-ChIP_EML_Mouse1.62755503
34CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.62434849
35NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.57305985
36DCP1A_22483619_ChIP-Seq_HELA_Human1.56799398
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.55561492
38CIITA_25753668_ChIP-Seq_RAJI_Human1.50290932
39E2F1_18555785_ChIP-Seq_MESCs_Mouse1.48076988
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.46962996
41TTF2_22483619_ChIP-Seq_HELA_Human1.46703616
42HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.46687526
43ELK1_19687146_ChIP-ChIP_HELA_Human1.46472224
44GABP_19822575_ChIP-Seq_HepG2_Human1.43759568
45TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.43088856
46NANOG_18555785_ChIP-Seq_MESCs_Mouse1.42757975
47PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.39718550
48SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.38355926
49SCL_19346495_ChIP-Seq_HPC-7_Human1.37586452
50SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.37478952
51MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.36752285
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.35868465
53VDR_21846776_ChIP-Seq_THP-1_Human1.34182348
54KDM5A_27292631_Chip-Seq_BREAST_Human1.33760555
55PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.33729958
56SPI1_23547873_ChIP-Seq_NB4_Human1.33510390
57MYB_21317192_ChIP-Seq_ERMYB_Mouse1.33247018
58E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.30426723
59POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.29001715
60ERG_20887958_ChIP-Seq_HPC-7_Mouse1.27986189
61YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27561897
62IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.24364928
63IRF8_21731497_ChIP-ChIP_J774_Mouse1.23462861
64BP1_19119308_ChIP-ChIP_Hs578T_Human1.21798543
65CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.16308852
66HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.14535556
67THAP11_20581084_ChIP-Seq_MESCs_Mouse1.10791908
68GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.09141874
69NOTCH1_21737748_ChIP-Seq_TLL_Human1.08073537
70PADI4_21655091_ChIP-ChIP_MCF-7_Human1.07807444
71SRF_21415370_ChIP-Seq_HL-1_Mouse1.07759099
72ZFX_18555785_ChIP-Seq_MESCs_Mouse1.05628325
73MYC_18940864_ChIP-ChIP_HL60_Human1.03971178
74TFEB_21752829_ChIP-Seq_HELA_Human1.02408121
75MYB_26560356_Chip-Seq_TH2_Human0.99873068
76KLF4_18555785_ChIP-Seq_MESCs_Mouse0.98435808
77CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.97648496
78E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.97041256
79MYB_26560356_Chip-Seq_TH1_Human0.96894888
80SALL1_21062744_ChIP-ChIP_HESCs_Human0.96840868
81RUNX1_22412390_ChIP-Seq_EML_Mouse0.96184654
82SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.95810340
83CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95685606
84RBPJ_22232070_ChIP-Seq_NCS_Mouse0.95137709
85HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.94460627
86BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90962589
87YY1_21170310_ChIP-Seq_MESCs_Mouse0.90366253
88CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.89472680
89DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.89027217
90TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.88533350
91CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.88028123
92CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.87519411
93CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.87466326
94ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.86513332
95STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.85821757
96IRF8_22096565_ChIP-ChIP_GC-B_Human0.85668061
97SOX17_20123909_ChIP-Seq_XEN_Mouse0.84387287
98GATA2_22383799_ChIP-Seq_G1ME_Mouse0.84103530
99POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.83232523
100ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.82944894
101UTX_26944678_Chip-Seq_JUKART_Human0.80672992
102BRD4_27068464_Chip-Seq_AML-cells_Mouse0.80228675
103STAT4_19710469_ChIP-ChIP_TH1__Mouse0.78551106
104ESR1_15608294_ChIP-ChIP_MCF-7_Human0.77328830
105CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.77102715
106HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.76789488
107RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.76571648
108SOX2_18555785_ChIP-Seq_MESCs_Mouse0.75724075
109MAF_26560356_Chip-Seq_TH1_Human0.74906306
110CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.74211447
111GATA1_22383799_ChIP-Seq_G1ME_Mouse0.73109909
112MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.71161053
113NANOG_21062744_ChIP-ChIP_HESCs_Human0.71066038
114STAT3_1855785_ChIP-Seq_MESCs_Mouse0.70754736
115HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.70096009
116TBX5_21415370_ChIP-Seq_HL-1_Mouse0.69414529
117STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.69032462
118CHD1_26751641_Chip-Seq_LNCaP_Human0.68306771
119DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.68303531
120NANOG_16153702_ChIP-ChIP_HESCs_Human0.67651460
121FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.67604332
122VDR_24763502_ChIP-Seq_THP-1_Human0.67588739
123ELF5_23300383_ChIP-Seq_T47D_Human0.66401804
124ELK1_22589737_ChIP-Seq_MCF10A_Human0.63963272
125TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.63031849
126KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.60848725

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.01038180
2MP0003693_abnormal_embryo_hatching4.79636172
3MP0003111_abnormal_nucleus_morphology4.58259141
4MP0008057_abnormal_DNA_replication4.02336493
5MP0003077_abnormal_cell_cycle3.99797809
6MP0004957_abnormal_blastocyst_morpholog3.59668515
7MP0002396_abnormal_hematopoietic_system3.09354811
8MP0008877_abnormal_DNA_methylation2.94140177
9MP0008058_abnormal_DNA_repair2.86002082
10MP0008007_abnormal_cellular_replicative2.54005272
11MP0003806_abnormal_nucleotide_metabolis2.39908445
12MP0003718_maternal_effect2.32251653
13MP0008932_abnormal_embryonic_tissue2.20936697
14MP0010307_abnormal_tumor_latency2.16757698
15MP0004808_abnormal_hematopoietic_stem2.09632465
16MP0000350_abnormal_cell_proliferation2.02688005
17MP0000490_abnormal_crypts_of2.02539483
18MP0001545_abnormal_hematopoietic_system1.85853026
19MP0005397_hematopoietic_system_phenotyp1.85853026
20MP0003786_premature_aging1.66692712
21MP0001730_embryonic_growth_arrest1.61662213
22MP0003950_abnormal_plasma_membrane1.61351350
23MP0010352_gastrointestinal_tract_polyps1.60807451
24MP0002019_abnormal_tumor_incidence1.58548107
25MP0006035_abnormal_mitochondrial_morpho1.58009410
26MP0003763_abnormal_thymus_physiology1.56984425
27MP0002398_abnormal_bone_marrow1.56306294
28MP0006292_abnormal_olfactory_placode1.54768672
29MP0000313_abnormal_cell_death1.45092181
30MP0003123_paternal_imprinting1.43534978
31MP0002210_abnormal_sex_determination1.43149633
32MP0006036_abnormal_mitochondrial_physio1.42213100
33MP0001119_abnormal_female_reproductive1.39801934
34MP0005174_abnormal_tail_pigmentation1.39243382
35MP0001672_abnormal_embryogenesis/_devel1.39097320
36MP0005380_embryogenesis_phenotype1.39097320
37MP0000358_abnormal_cell_content/1.38169543
38MP0003121_genomic_imprinting1.37994793
39MP0000465_gastrointestinal_hemorrhage1.36521231
40MP0000703_abnormal_thymus_morphology1.33732740
41MP0001929_abnormal_gametogenesis1.31883681
42MP0001697_abnormal_embryo_size1.31019377
43MP0002722_abnormal_immune_system1.29987633
44MP0000689_abnormal_spleen_morphology1.28267669
45MP0001835_abnormal_antigen_presentation1.26918733
46MP0005451_abnormal_body_composition1.25091395
47MP0003186_abnormal_redox_activity1.24547981
48MP0000653_abnormal_sex_gland1.22061148
49MP0003984_embryonic_growth_retardation1.20576258
50MP0009333_abnormal_splenocyte_physiolog1.19580099
51MP0002085_abnormal_embryonic_tissue1.17424829
52MP0006054_spinal_hemorrhage1.17031746
53MP0002088_abnormal_embryonic_growth/wei1.16462355
54MP0002429_abnormal_blood_cell1.16459197
55MP0002080_prenatal_lethality1.16458146
56MP0001145_abnormal_male_reproductive1.14189938
57MP0001800_abnormal_humoral_immune1.13817522
58MP0005395_other_phenotype1.13105691
59MP0000716_abnormal_immune_system1.12927529
60MP0002086_abnormal_extraembryonic_tissu1.12762872
61MP0009278_abnormal_bone_marrow1.12613531
62MP0002452_abnormal_antigen_presenting1.09811239
63MP0002420_abnormal_adaptive_immunity1.07425331
64MP0001819_abnormal_immune_cell1.06391143
65MP0003566_abnormal_cell_adhesion1.04750552
66MP0005464_abnormal_platelet_physiology1.04238230
67MP0002095_abnormal_skin_pigmentation1.04046478
68MP0003699_abnormal_female_reproductive1.03780402
69MP0005076_abnormal_cell_differentiation1.03175830
70MP0001915_intracranial_hemorrhage1.02821190
71MP0003941_abnormal_skin_development1.01761428
72MP0005408_hypopigmentation1.01197014
73MP0001293_anophthalmia0.99454448
74MP0005671_abnormal_response_to0.98789683
75MP0002084_abnormal_developmental_patter0.98718285
76MP0002723_abnormal_immune_serum0.97182546
77MP0009672_abnormal_birth_weight0.95880998
78MP0000372_irregular_coat_pigmentation0.95410246
79MP0005410_abnormal_fertilization0.94910451
80MP0003436_decreased_susceptibility_to0.94896498
81MP0000569_abnormal_digit_pigmentation0.94647390
82MP0001986_abnormal_taste_sensitivity0.94118385
83MP0002160_abnormal_reproductive_system0.93514709
84MP0003787_abnormal_imprinting0.93122102
85MP0002419_abnormal_innate_immunity0.92020500
86MP0004147_increased_porphyrin_level0.90057752
87MP0004197_abnormal_fetal_growth/weight/0.89374671
88MP0003890_abnormal_embryonic-extraembry0.88066981
89MP0003656_abnormal_erythrocyte_physiolo0.87088208
90MP0003698_abnormal_male_reproductive0.86195136
91MP0009697_abnormal_copulation0.84941535
92MP0005025_abnormal_response_to0.84801168
93MP0001881_abnormal_mammary_gland0.84159990
94MP0003567_abnormal_fetal_cardiomyocyte0.83785112
95MP0000858_altered_metastatic_potential0.82939075
96MP0005501_abnormal_skin_physiology0.82665185
97MP0002006_tumorigenesis0.82613218
98MP0009785_altered_susceptibility_to0.82500674
99MP0010155_abnormal_intestine_physiology0.82345945
100MP0002405_respiratory_system_inflammati0.82338679
101MP0004264_abnormal_extraembryonic_tissu0.82190490
102MP0005621_abnormal_cell_physiology0.81602155
103MP0008995_early_reproductive_senescence0.81287303
104MP0002102_abnormal_ear_morphology0.78486111
105MP0003943_abnormal_hepatobiliary_system0.78451690
106MP0002132_abnormal_respiratory_system0.78128379
107MP0001853_heart_inflammation0.76747578
108MP0010030_abnormal_orbit_morphology0.75840078
109MP0008789_abnormal_olfactory_epithelium0.75259878
110MP0005000_abnormal_immune_tolerance0.74668318
111MP0005384_cellular_phenotype0.73003061
112MP0001346_abnormal_lacrimal_gland0.72031307
113MP0002075_abnormal_coat/hair_pigmentati0.71839352
114MP0002877_abnormal_melanocyte_morpholog0.70620867
115MP0000015_abnormal_ear_pigmentation0.69950893
116MP0000685_abnormal_immune_system0.69720109
117MP0002796_impaired_skin_barrier0.69524495
118MP0005075_abnormal_melanosome_morpholog0.67788164
119MP0002234_abnormal_pharynx_morphology0.67594808
120MP0003448_altered_tumor_morphology0.64892670
121MP0003315_abnormal_perineum_morphology0.64661820
122MP0003221_abnormal_cardiomyocyte_apopto0.64396336
123MP0002161_abnormal_fertility/fecundity0.63645728
124MP0005387_immune_system_phenotype0.62392703
125MP0001790_abnormal_immune_system0.62392703
126MP0003937_abnormal_limbs/digits/tail_de0.61405861
127MP0004185_abnormal_adipocyte_glucose0.60487392
128MP0005389_reproductive_system_phenotype0.60330399
129MP0001529_abnormal_vocalization0.59101056
130MP0000627_abnormal_mammary_gland0.58981677
131MP0002938_white_spotting0.58493530
132MP0001727_abnormal_embryo_implantation0.57492772
133MP0005171_absent_coat_pigmentation0.56551806
134MP0001764_abnormal_homeostasis0.56175845
135MP0002970_abnormal_white_adipose0.55281125
136MP0009703_decreased_birth_body0.53248792
137MP0001661_extended_life_span0.51280398
138MP0000678_abnormal_parathyroid_gland0.49004754
139MP0003936_abnormal_reproductive_system0.48729740

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)5.83967928
2Chromosomal breakage induced by crosslinking agents (HP:0003221)5.33657436
3Birth length less than 3rd percentile (HP:0003561)4.68768785
4Abnormality of chromosome stability (HP:0003220)3.85849379
5Microvesicular hepatic steatosis (HP:0001414)3.59859738
6Myelodysplasia (HP:0002863)3.40719526
7Abnormality of glycolysis (HP:0004366)3.38992878
8Patellar aplasia (HP:0006443)3.25959666
9Increased serum pyruvate (HP:0003542)3.24757659
10Breast hypoplasia (HP:0003187)3.13627241
11Meckel diverticulum (HP:0002245)3.11277249
12Reticulocytopenia (HP:0001896)3.08598378
13Ectopic kidney (HP:0000086)3.07430094
14Abnormality of the preputium (HP:0100587)3.07149179
15Aplasia/Hypoplasia of the uvula (HP:0010293)3.03466578
16Aplastic anemia (HP:0001915)3.02983644
17Abnormality of the ileum (HP:0001549)2.96199554
18Aplasia/Hypoplasia of the patella (HP:0006498)2.95155197
19Volvulus (HP:0002580)2.83850649
20Small intestinal stenosis (HP:0012848)2.81354155
21Duodenal stenosis (HP:0100867)2.81354155
22Duplicated collecting system (HP:0000081)2.73589724
23Abnormality of DNA repair (HP:0003254)2.69700428
24Abnormality of the fingertips (HP:0001211)2.69593470
25Abnormal gallbladder physiology (HP:0012438)2.65544611
26Cholecystitis (HP:0001082)2.65544611
27Aplasia/Hypoplasia of the sacrum (HP:0008517)2.64611878
28Thrombocytosis (HP:0001894)2.63935572
29Clubbing of toes (HP:0100760)2.62537158
30Abnormality of the renal collecting system (HP:0004742)2.61871781
31Bone marrow hypocellularity (HP:0005528)2.61646140
32Hypoplasia of the capital femoral epiphysis (HP:0003090)2.60876610
33Impulsivity (HP:0100710)2.59224189
34Medulloblastoma (HP:0002885)2.58996591
35Multiple enchondromatosis (HP:0005701)2.50691822
36Abnormality of the labia minora (HP:0012880)2.49614496
37Facial hemangioma (HP:0000329)2.49111654
38Acute necrotizing encephalopathy (HP:0006965)2.47646213
39Acute myeloid leukemia (HP:0004808)2.45024809
40Abnormal lung lobation (HP:0002101)2.43593986
41Increased nuchal translucency (HP:0010880)2.42906147
42Sloping forehead (HP:0000340)2.42885000
43Absent thumb (HP:0009777)2.37217588
44Rhabdomyosarcoma (HP:0002859)2.36882677
45Selective tooth agenesis (HP:0001592)2.34865359
46Acute encephalopathy (HP:0006846)2.33774173
47Agnosia (HP:0010524)2.33510486
48Abnormality of cochlea (HP:0000375)2.31233414
49Carpal bone hypoplasia (HP:0001498)2.30031644
50Abnormal mitochondria in muscle tissue (HP:0008316)2.29643153
51Abnormality of the prostate (HP:0008775)2.27028154
52Absent radius (HP:0003974)2.26997560
53IgM deficiency (HP:0002850)2.25801808
54Abnormality of the carotid arteries (HP:0005344)2.25290631
55Increased serum lactate (HP:0002151)2.24996409
56High pitched voice (HP:0001620)2.24552115
57Increased CSF lactate (HP:0002490)2.24374457
58Increased hepatocellular lipid droplets (HP:0006565)2.23604795
59Progressive muscle weakness (HP:0003323)2.22769700
60Abnormality of the anterior horn cell (HP:0006802)2.21400558
61Degeneration of anterior horn cells (HP:0002398)2.21400558
62Nephroblastoma (Wilms tumor) (HP:0002667)2.20910615
63Choanal atresia (HP:0000453)2.20772977
64Reduced antithrombin III activity (HP:0001976)2.17358013
65Short thumb (HP:0009778)2.15800376
66Recurrent abscess formation (HP:0002722)2.12884871
67Absent forearm bone (HP:0003953)2.12818606
68Aplasia involving forearm bones (HP:0009822)2.12818606
69Amaurosis fugax (HP:0100576)2.12662637
7011 pairs of ribs (HP:0000878)2.11991320
71Abnormality of the duodenum (HP:0002246)2.11917219
72Pulmonary fibrosis (HP:0002206)2.11183479
73Arteriovenous malformation (HP:0100026)2.10579389
74Cafe-au-lait spot (HP:0000957)2.09856505
75Type I transferrin isoform profile (HP:0003642)2.09667281
76Oral leukoplakia (HP:0002745)2.09247583
77Premature graying of hair (HP:0002216)2.07542679
78Squamous cell carcinoma (HP:0002860)2.06067108
79Acute lymphatic leukemia (HP:0006721)2.04299140
80Embryonal renal neoplasm (HP:0011794)2.03982291
81Aplasia/Hypoplasia of the sternum (HP:0006714)2.03748902
82Absent epiphyses (HP:0010577)2.01893609
83Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.01893609
84Secondary amenorrhea (HP:0000869)2.00768813
85Premature ovarian failure (HP:0008209)2.00230728
86Lipid accumulation in hepatocytes (HP:0006561)1.99498318
87Hypergonadotropic hypogonadism (HP:0000815)1.99379758
88Prominent nose (HP:0000448)1.99121831
89Prostate neoplasm (HP:0100787)1.98962669
90Embryonal neoplasm (HP:0002898)1.98674399
91Progressive external ophthalmoplegia (HP:0000590)1.98145205
92Poikiloderma (HP:0001029)1.98101729
93Deviation of the thumb (HP:0009603)1.97772279
94Proximal placement of thumb (HP:0009623)1.97353769
95Lymphoma (HP:0002665)1.96765747
96Overlapping toe (HP:0001845)1.96549666
97Abnormality of methionine metabolism (HP:0010901)1.95441702
98Recurrent viral infections (HP:0004429)1.94682995
99Abnormal umbilical cord blood vessels (HP:0011403)1.93650717
100Single umbilical artery (HP:0001195)1.93650717
101Abnormality of the fetal cardiovascular system (HP:0010948)1.93650717
102Pancytopenia (HP:0001876)1.92344710
103Mitochondrial inheritance (HP:0001427)1.90771885
104Supernumerary spleens (HP:0009799)1.90279682
105Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.90245196
106Cortical dysplasia (HP:0002539)1.89092402
107Abnormality of chromosome segregation (HP:0002916)1.89028604
108Progressive macrocephaly (HP:0004481)1.88051249
109Entropion (HP:0000621)1.87158256
110Horseshoe kidney (HP:0000085)1.86605850
111Cerebral edema (HP:0002181)1.86353628
112Recurrent bacterial skin infections (HP:0005406)1.85713425
113Rough bone trabeculation (HP:0100670)1.85099925
114Deep philtrum (HP:0002002)1.84213427
115Abnormal protein glycosylation (HP:0012346)1.82143015
116Abnormal glycosylation (HP:0012345)1.82143015
117Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.82143015
118Abnormal protein N-linked glycosylation (HP:0012347)1.82143015
119Myositis (HP:0100614)1.78221453
120Basal cell carcinoma (HP:0002671)1.77178205
121Aplasia/Hypoplasia of the earlobes (HP:0009906)1.76303760
122Chronic otitis media (HP:0000389)1.76039210
123Abnormality of cells of the erythroid lineage (HP:0012130)1.75362877
124Petechiae (HP:0000967)1.73893078
125Ureteral duplication (HP:0000073)1.73354039
126Tracheoesophageal fistula (HP:0002575)1.73232386
127Neoplasm of the colon (HP:0100273)1.72417041
128Abnormality of the proximal phalanges of the hand (HP:0009834)1.72270415
129Abnormal number of erythroid precursors (HP:0012131)1.72211585
130Abnormal spermatogenesis (HP:0008669)1.71227450
131Sparse eyelashes (HP:0000653)1.70701121
132Slender long bone (HP:0003100)1.70613124
133Abnormality of the umbilical cord (HP:0010881)1.70373158
134Atresia of the external auditory canal (HP:0000413)1.70353609
135Abnormality of the pons (HP:0007361)1.70016464
136Combined immunodeficiency (HP:0005387)1.69936960
137Ependymoma (HP:0002888)1.69458495
138Irregular epiphyses (HP:0010582)1.69406319
139Exercise intolerance (HP:0003546)1.68724013
140Abnormality of lateral ventricle (HP:0030047)1.68115700
141Blepharitis (HP:0000498)1.67673514
142Pallor (HP:0000980)1.67529558
143Panhypogammaglobulinemia (HP:0003139)1.67308558
144Triphalangeal thumb (HP:0001199)1.67022414
145Cutaneous melanoma (HP:0012056)1.65991567
146Flared metaphyses (HP:0003015)1.64139095

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.57139703
2BUB13.64165476
3WEE13.61228313
4TTK3.18951807
5STK102.91842598
6NEK22.88849622
7BRSK22.83071885
8MST42.81183990
9PLK42.79871906
10VRK22.55350816
11ACVR1B2.26791288
12PLK12.14504392
13SRPK12.11803349
14TAOK32.05015462
15EIF2AK12.04933053
16EEF2K1.87600755
17MAP3K61.84075878
18ATR1.81045221
19CDK121.79570190
20CHEK21.69005213
21CDK81.68439479
22MAP3K81.68130445
23AURKB1.67219514
24MKNK11.59631694
25STK41.57996265
26CDK71.54303554
27MAP4K11.50656364
28KIT1.50504649
29BRSK11.46599744
30CDK41.46411685
31RPS6KB21.45751046
32PLK31.44947005
33STK31.39671325
34NEK11.31571537
35MKNK21.30969837
36CCNB11.24785275
37CLK11.24000025
38VRK11.23535912
39IRAK41.22514677
40JAK31.19432973
41NME11.18305268
42CHEK11.17082973
43SCYL21.13016530
44FLT31.12607337
45BMPR21.10506377
46TAF11.10262560
47MELK1.08624538
48TRIM281.07263076
49STK38L1.06924881
50TEC1.02059172
51PNCK1.00800249
52MOS0.98463219
53ATM0.98294349
54PIM10.96405017
55NME20.95299142
56ZAK0.95075000
57AURKA0.93041098
58RPS6KA40.92183140
59BRAF0.89981039
60BLK0.87520203
61BTK0.87073671
62SIK30.85665718
63LRRK20.84642343
64TGFBR10.82315222
65LATS10.80752451
66TSSK60.78606710
67TXK0.78035067
68DYRK30.76987546
69CDK20.76982687
70SMG10.76860775
71NEK90.75965895
72PDK20.72563316
73BRD40.71284613
74MAP3K100.70197262
75CDK90.68863425
76PAK40.68841653
77CDK60.68347417
78LATS20.67386000
79STK240.63106703
80STK160.62563011
81MST1R0.61605415
82EIF2AK30.61434299
83CDK10.60355835
84EIF2AK20.59873343
85PASK0.59780254
86ARAF0.56714544
87ALK0.56334991
88MAP3K50.53738925
89ZAP700.53582334
90TESK20.52448515
91MATK0.49874451
92TRPM70.49646788
93RAF10.49127495
94PRKCI0.46676737
95CSF1R0.46219335
96IRAK30.44322342
97CSNK2A10.44022913
98SYK0.43871645
99MAP2K30.43208265
100MARK30.42248355
101PBK0.42102716
102LYN0.39730477
103BMPR1B0.39351673
104MAP3K140.37427738
105PAK10.34257731
106NUAK10.33219777
107TAOK10.32855789
108PIM20.32715712
109ERBB40.31630200
110PLK20.31034276
111CSNK1E0.30815635
112AKT10.30625146
113AKT20.30484911
114MET0.29852238
115CSNK2A20.29132810
116MAP3K130.28645928
117NEK60.25433899
118MAPK140.24229582
119MAPKAPK30.24037737
120TLK10.22896770
121CDK180.22692821
122DAPK10.22006753
123CDK140.21935056
124CDK11A0.21929913
125MAPKAPK50.21547796
126CDK30.21062191
127CDK150.20544223
128PRKDC0.20494572
129ILK0.16924408
130MAP3K90.16599792
131BCR0.11768133

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.90994440
2Mismatch repair_Homo sapiens_hsa034304.02658284
3Homologous recombination_Homo sapiens_hsa034403.58302864
4Cell cycle_Homo sapiens_hsa041103.46606058
5Base excision repair_Homo sapiens_hsa034103.08686610
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.89327163
7Fanconi anemia pathway_Homo sapiens_hsa034602.85648644
8RNA transport_Homo sapiens_hsa030132.66835693
9Nucleotide excision repair_Homo sapiens_hsa034202.66714669
10RNA polymerase_Homo sapiens_hsa030202.56347847
11Spliceosome_Homo sapiens_hsa030402.55858665
12Non-homologous end-joining_Homo sapiens_hsa034502.48321855
13Basal transcription factors_Homo sapiens_hsa030222.20508101
14RNA degradation_Homo sapiens_hsa030182.19960199
15One carbon pool by folate_Homo sapiens_hsa006702.19084436
16Pyrimidine metabolism_Homo sapiens_hsa002402.13927402
17p53 signaling pathway_Homo sapiens_hsa041151.86364480
18Protein export_Homo sapiens_hsa030601.70294215
19mRNA surveillance pathway_Homo sapiens_hsa030151.67895054
20Ribosome_Homo sapiens_hsa030101.58745608
21Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.51908763
22Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.44614459
23Proteasome_Homo sapiens_hsa030501.43971326
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.39694828
25Herpes simplex infection_Homo sapiens_hsa051681.32467718
26Oocyte meiosis_Homo sapiens_hsa041141.23481507
27Parkinsons disease_Homo sapiens_hsa050121.20782197
28Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.16971689
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.14724853
30Purine metabolism_Homo sapiens_hsa002301.10800385
31Epstein-Barr virus infection_Homo sapiens_hsa051691.10514310
32Biosynthesis of amino acids_Homo sapiens_hsa012301.06919624
33Oxidative phosphorylation_Homo sapiens_hsa001901.05738705
34Fatty acid elongation_Homo sapiens_hsa000621.05371708
35Pyruvate metabolism_Homo sapiens_hsa006201.05095668
36Huntingtons disease_Homo sapiens_hsa050161.02948037
37Primary immunodeficiency_Homo sapiens_hsa053401.02819065
38Viral carcinogenesis_Homo sapiens_hsa052031.02419150
39Antigen processing and presentation_Homo sapiens_hsa046121.01484090
40Measles_Homo sapiens_hsa051620.99506872
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.96792485
42Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96034801
43NF-kappa B signaling pathway_Homo sapiens_hsa040640.95298017
44MicroRNAs in cancer_Homo sapiens_hsa052060.94625110
45Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.92904634
46HTLV-I infection_Homo sapiens_hsa051660.90214377
47Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.89141791
48Carbon metabolism_Homo sapiens_hsa012000.88984899
49Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.86282075
50Sulfur relay system_Homo sapiens_hsa041220.82999757
51Hepatitis B_Homo sapiens_hsa051610.82323420
52Propanoate metabolism_Homo sapiens_hsa006400.82171117
53Small cell lung cancer_Homo sapiens_hsa052220.80793117
54Leishmaniasis_Homo sapiens_hsa051400.79776784
55Apoptosis_Homo sapiens_hsa042100.79694008
56Systemic lupus erythematosus_Homo sapiens_hsa053220.78584479
57Glutathione metabolism_Homo sapiens_hsa004800.76452084
58Vitamin B6 metabolism_Homo sapiens_hsa007500.76258475
59Hematopoietic cell lineage_Homo sapiens_hsa046400.75691817
60RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.74583822
61Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.74508295
62Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.73623749
63Pancreatic cancer_Homo sapiens_hsa052120.72511254
64Intestinal immune network for IgA production_Homo sapiens_hsa046720.70507834
65Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.66893171
66Influenza A_Homo sapiens_hsa051640.66859264
67Chronic myeloid leukemia_Homo sapiens_hsa052200.66807645
68Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.65581154
69Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.65081547
70Steroid biosynthesis_Homo sapiens_hsa001000.64659261
71Shigellosis_Homo sapiens_hsa051310.64002900
72Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.62020737
73Legionellosis_Homo sapiens_hsa051340.61636809
74NOD-like receptor signaling pathway_Homo sapiens_hsa046210.61339261
75Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.61329567
76Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.61286105
77TGF-beta signaling pathway_Homo sapiens_hsa043500.59921010
78Thyroid cancer_Homo sapiens_hsa052160.58988475
79Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.58436472
80Alzheimers disease_Homo sapiens_hsa050100.53316248
81Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.53271244
82B cell receptor signaling pathway_Homo sapiens_hsa046620.52020139
83Colorectal cancer_Homo sapiens_hsa052100.51411254
84Acute myeloid leukemia_Homo sapiens_hsa052210.50970153
85Non-small cell lung cancer_Homo sapiens_hsa052230.50526094
86Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.50148428
87Pentose phosphate pathway_Homo sapiens_hsa000300.48552906
88Toll-like receptor signaling pathway_Homo sapiens_hsa046200.48358752
89N-Glycan biosynthesis_Homo sapiens_hsa005100.47923310
90Jak-STAT signaling pathway_Homo sapiens_hsa046300.47185143
91Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46869789
92Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.46604237
93Selenocompound metabolism_Homo sapiens_hsa004500.45827271
94Glycosaminoglycan degradation_Homo sapiens_hsa005310.45792246
95Metabolic pathways_Homo sapiens_hsa011000.44813285
96Other glycan degradation_Homo sapiens_hsa005110.39272059
97Toxoplasmosis_Homo sapiens_hsa051450.39183167
98Lysine degradation_Homo sapiens_hsa003100.38806274
99Viral myocarditis_Homo sapiens_hsa054160.36532014
100Malaria_Homo sapiens_hsa051440.36238296
101Osteoclast differentiation_Homo sapiens_hsa043800.35238196
102FoxO signaling pathway_Homo sapiens_hsa040680.34573646
103Asthma_Homo sapiens_hsa053100.34415562
104Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.34368518
105Notch signaling pathway_Homo sapiens_hsa043300.34305716
106Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32548047
107Drug metabolism - other enzymes_Homo sapiens_hsa009830.32140159
108TNF signaling pathway_Homo sapiens_hsa046680.32085188
109Sulfur metabolism_Homo sapiens_hsa009200.31908930
110HIF-1 signaling pathway_Homo sapiens_hsa040660.31303203
111Platelet activation_Homo sapiens_hsa046110.30690315
112Allograft rejection_Homo sapiens_hsa053300.30592806
113Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.30328280
114Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.29799727
115Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.29293357
116Pathways in cancer_Homo sapiens_hsa052000.29255386
117Ovarian steroidogenesis_Homo sapiens_hsa049130.28582268
118Cyanoamino acid metabolism_Homo sapiens_hsa004600.27793094
119Tuberculosis_Homo sapiens_hsa051520.27716741
120Leukocyte transendothelial migration_Homo sapiens_hsa046700.27400410
121Fructose and mannose metabolism_Homo sapiens_hsa000510.26949469
122Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.26889466
123Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.26576079
124Fatty acid metabolism_Homo sapiens_hsa012120.26504772
125Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.26475517
126Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.25433287
127Folate biosynthesis_Homo sapiens_hsa007900.25258438
128mTOR signaling pathway_Homo sapiens_hsa041500.25070032
129Cysteine and methionine metabolism_Homo sapiens_hsa002700.24883051
130Melanoma_Homo sapiens_hsa052180.24773764
131Arachidonic acid metabolism_Homo sapiens_hsa005900.23264181
132Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.21644754
133Alcoholism_Homo sapiens_hsa050340.15963251
134Prostate cancer_Homo sapiens_hsa052150.13331487
135Galactose metabolism_Homo sapiens_hsa000520.12249121
136Bladder cancer_Homo sapiens_hsa052190.12183032
137Arginine and proline metabolism_Homo sapiens_hsa003300.09447667
138SNARE interactions in vesicular transport_Homo sapiens_hsa041300.07883535
139Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.06621340
140Central carbon metabolism in cancer_Homo sapiens_hsa052300.06381922
141Adherens junction_Homo sapiens_hsa04520-0.0242034
142Vitamin digestion and absorption_Homo sapiens_hsa04977-0.0196707

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