MTG1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.55989156
2ATP synthesis coupled proton transport (GO:0015986)6.14605576
3energy coupled proton transport, down electrochemical gradient (GO:0015985)6.14605576
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.66328383
5respiratory electron transport chain (GO:0022904)5.10126319
6proteasome assembly (GO:0043248)5.05723656
7electron transport chain (GO:0022900)5.01741866
8oxidative phosphorylation (GO:0006119)4.92402190
9L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.73759690
10mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.57070119
11mitochondrial respiratory chain complex I assembly (GO:0032981)4.57070119
12NADH dehydrogenase complex assembly (GO:0010257)4.57070119
13L-methionine salvage (GO:0071267)4.41603737
14L-methionine biosynthetic process (GO:0071265)4.41603737
15amino acid salvage (GO:0043102)4.41603737
16protein complex biogenesis (GO:0070271)4.38181845
17transcription elongation from RNA polymerase III promoter (GO:0006385)4.31858577
18termination of RNA polymerase III transcription (GO:0006386)4.31858577
19chaperone-mediated protein transport (GO:0072321)4.16764561
20mitochondrial respiratory chain complex assembly (GO:0033108)4.04995247
21establishment of protein localization to mitochondrial membrane (GO:0090151)3.99636923
22maturation of 5.8S rRNA (GO:0000460)3.93706661
23cullin deneddylation (GO:0010388)3.89054939
24DNA strand elongation involved in DNA replication (GO:0006271)3.84880413
25protein targeting to mitochondrion (GO:0006626)3.83149189
26establishment of protein localization to mitochondrion (GO:0072655)3.82377712
27GTP biosynthetic process (GO:0006183)3.79979765
28pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.78475614
29* regulation of mitochondrial translation (GO:0070129)3.77920237
30DNA strand elongation (GO:0022616)3.71821028
31pseudouridine synthesis (GO:0001522)3.71253361
32guanosine-containing compound biosynthetic process (GO:1901070)3.71023191
33NADH metabolic process (GO:0006734)3.69219750
34negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.67106105
35protein deneddylation (GO:0000338)3.62071534
36regulation of cellular amino acid metabolic process (GO:0006521)3.61660241
37protein neddylation (GO:0045116)3.57985000
38respiratory chain complex IV assembly (GO:0008535)3.56873128
39GDP-mannose metabolic process (GO:0019673)3.54571344
40telomere maintenance via semi-conservative replication (GO:0032201)3.53242893
41deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.51976783
42peptidyl-histidine modification (GO:0018202)3.48924287
43protein localization to mitochondrion (GO:0070585)3.47687434
44base-excision repair, AP site formation (GO:0006285)3.47532891
45purine nucleoside triphosphate biosynthetic process (GO:0009145)3.46464924
46purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.46127955
47DNA damage response, detection of DNA damage (GO:0042769)3.45042801
48DNA ligation (GO:0006266)3.43401243
49positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.43314227
50protein maturation by protein folding (GO:0022417)3.43049697
51purine nucleobase biosynthetic process (GO:0009113)3.39493464
52negative regulation of ligase activity (GO:0051352)3.38084933
53negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.38084933
54rRNA modification (GO:0000154)3.36790384
55ubiquinone biosynthetic process (GO:0006744)3.36608617
56quinone biosynthetic process (GO:1901663)3.36608617
57ATP biosynthetic process (GO:0006754)3.36456009
58UTP biosynthetic process (GO:0006228)3.32537275
597-methylguanosine mRNA capping (GO:0006370)3.32123687
60spliceosomal snRNP assembly (GO:0000387)3.31553719
61pyrimidine nucleotide catabolic process (GO:0006244)3.28571740
62regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.27673063
63viral mRNA export from host cell nucleus (GO:0046784)3.27328624
64establishment of viral latency (GO:0019043)3.26875688
65RNA capping (GO:0036260)3.25966734
667-methylguanosine RNA capping (GO:0009452)3.25966734
67deoxyribonucleotide catabolic process (GO:0009264)3.25699028
68protein-cofactor linkage (GO:0018065)3.24781515
69nucleobase biosynthetic process (GO:0046112)3.23944772
70L-serine metabolic process (GO:0006563)3.19260094
71anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.18490455
72negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.16740938
73methionine biosynthetic process (GO:0009086)3.16650994
74regulation of oxidative phosphorylation (GO:0002082)3.15436762
75ribonucleoside triphosphate biosynthetic process (GO:0009201)3.14797896
76dopamine transport (GO:0015872)3.14501971
77aerobic respiration (GO:0009060)3.13127792
78deoxyribose phosphate catabolic process (GO:0046386)3.12524723
79mitochondrial transport (GO:0006839)3.08508498
80establishment of integrated proviral latency (GO:0075713)3.08481018
81hydrogen ion transmembrane transport (GO:1902600)3.06980748
82cytochrome complex assembly (GO:0017004)3.06777264
83GMP metabolic process (GO:0046037)3.05915067
84methionine metabolic process (GO:0006555)3.04554010
85DNA deamination (GO:0045006)3.04389524
86pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.04319198
87ribosomal small subunit assembly (GO:0000028)3.04318444
88ubiquinone metabolic process (GO:0006743)3.03598501
89proline biosynthetic process (GO:0006561)3.03105874
90DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.02818701
91peptidyl-arginine omega-N-methylation (GO:0035247)3.02407381
92inner mitochondrial membrane organization (GO:0007007)3.02077259
93purine deoxyribonucleotide catabolic process (GO:0009155)3.01132375
94chromatin remodeling at centromere (GO:0031055)2.99969492
95pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.99383856
96regulation of cellular respiration (GO:0043457)2.98969071
97UTP metabolic process (GO:0046051)2.98430582
98regulation of double-strand break repair via homologous recombination (GO:0010569)2.98382383
99base-excision repair (GO:0006284)2.96793500
100tricarboxylic acid cycle (GO:0006099)2.96586915
101negative regulation of mRNA processing (GO:0050686)2.96249408
102signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.94829611
103intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.94829611
104signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.94656555
105signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.94656555
106signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.94656555
107pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.94235635
108antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.94102058
109CTP biosynthetic process (GO:0006241)2.93273008
110CTP metabolic process (GO:0046036)2.93273008
111iron-sulfur cluster assembly (GO:0016226)2.92675537
112metallo-sulfur cluster assembly (GO:0031163)2.92675537
113positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.92586510
114formation of translation preinitiation complex (GO:0001731)2.91536814
115telomere maintenance via recombination (GO:0000722)2.90365465
116positive regulation of ligase activity (GO:0051351)2.89872859
117mitochondrial RNA metabolic process (GO:0000959)2.89680139
118DNA replication checkpoint (GO:0000076)2.89594468
119regulation of cellular amine metabolic process (GO:0033238)2.89503678
120translation (GO:0006412)2.88677162
121energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.87872970
122ATP hydrolysis coupled proton transport (GO:0015991)2.87872970
123regulation of cholesterol esterification (GO:0010872)2.87243182
124maturation of SSU-rRNA (GO:0030490)2.86535453
125nucleoside triphosphate biosynthetic process (GO:0009142)2.86386833
126signal transduction involved in DNA integrity checkpoint (GO:0072401)2.85808670
127signal transduction involved in DNA damage checkpoint (GO:0072422)2.85808670
128ribosomal small subunit biogenesis (GO:0042274)2.85204397
129DNA replication initiation (GO:0006270)2.84255580
130intracellular protein transmembrane import (GO:0044743)2.83537782
131proline metabolic process (GO:0006560)2.83037713
132CENP-A containing nucleosome assembly (GO:0034080)2.82881373
133* cellular component biogenesis (GO:0044085)2.82681406
134mitotic recombination (GO:0006312)2.82455060
135signal transduction involved in cell cycle checkpoint (GO:0072395)2.82337231
136regulation of acyl-CoA biosynthetic process (GO:0050812)2.82280506
137kinetochore assembly (GO:0051382)2.81799493
138deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.81762402
139rRNA methylation (GO:0031167)2.81469951
140transcription-coupled nucleotide-excision repair (GO:0006283)2.80630368
141branched-chain amino acid catabolic process (GO:0009083)2.80486029
142proton transport (GO:0015992)2.80401372
143pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.78024437
144RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.77333543
145tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.77333543
146somatic hypermutation of immunoglobulin genes (GO:0016446)2.76913136

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.95417107
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.73669370
3* JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.43015563
4GABP_17652178_ChIP-ChIP_JURKAT_Human4.39249360
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human4.29599526
6E2F7_22180533_ChIP-Seq_HELA_Human4.09279225
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.04452986
8EST1_17652178_ChIP-ChIP_JURKAT_Human4.01683767
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.96008529
10MYC_18555785_ChIP-Seq_MESCs_Mouse3.60753332
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.42254061
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.29182531
13CREB1_15753290_ChIP-ChIP_HEK293T_Human3.22367404
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.20029688
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.08049488
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.93556092
17* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.85289275
18PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.82082742
19SRF_21415370_ChIP-Seq_HL-1_Mouse2.78483029
20VDR_23849224_ChIP-Seq_CD4+_Human2.41681959
21* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.39485983
22ELF1_17652178_ChIP-ChIP_JURKAT_Human2.38304725
23THAP11_20581084_ChIP-Seq_MESCs_Mouse2.38119213
24E2F1_18555785_ChIP-Seq_MESCs_Mouse2.34663909
25* DCP1A_22483619_ChIP-Seq_HELA_Human2.31718049
26YY1_21170310_ChIP-Seq_MESCs_Mouse2.21806382
27MYC_19079543_ChIP-ChIP_MESCs_Mouse2.14016826
28XRN2_22483619_ChIP-Seq_HELA_Human1.99380492
29FOXP3_21729870_ChIP-Seq_TREG_Human1.97985283
30* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.90090408
31* GABP_19822575_ChIP-Seq_HepG2_Human1.88123823
32ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.82365157
33TTF2_22483619_ChIP-Seq_HELA_Human1.81817442
34NELFA_20434984_ChIP-Seq_ESCs_Mouse1.73043622
35* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.71275475
36FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.67425981
37POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.62328659
38ELK1_19687146_ChIP-ChIP_HELA_Human1.61555504
39CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.60196438
40CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.56524322
41YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.53880965
42PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.53163116
43CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.52546912
44ELK1_22589737_ChIP-Seq_MCF10A_Human1.51479485
45DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.46513039
46ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.45968491
47* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.36520051
48E2F1_21310950_ChIP-Seq_MCF-7_Human1.34432927
49TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.33704092
50BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.32639929
51MYC_18940864_ChIP-ChIP_HL60_Human1.31723188
52HOXB4_20404135_ChIP-ChIP_EML_Mouse1.30620389
53FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.28347159
54* FOXP1_21924763_ChIP-Seq_HESCs_Human1.27819473
55SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.26297132
56TAF15_26573619_Chip-Seq_HEK293_Human1.21988941
57NANOG_18555785_ChIP-Seq_MESCs_Mouse1.21655562
58IRF1_19129219_ChIP-ChIP_H3396_Human1.20915308
59* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.20855883
60CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.20236784
61TET1_21451524_ChIP-Seq_MESCs_Mouse1.19011692
62ZNF263_19887448_ChIP-Seq_K562_Human1.15228136
63DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.15120694
64TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14779390
65POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.13228910
66HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.12620572
67* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.11810902
68CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.10255271
69SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.08790478
70E2F4_17652178_ChIP-ChIP_JURKAT_Human1.06988251
71* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.06551629
72ESR1_15608294_ChIP-ChIP_MCF-7_Human1.06429790
73ELF1_20517297_ChIP-Seq_JURKAT_Human1.06314951
74* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.05340366
75VDR_21846776_ChIP-Seq_THP-1_Human1.05284896
76MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.04968001
77CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.03656737
78FOXM1_23109430_ChIP-Seq_U2OS_Human1.03335490
79KDM5A_27292631_Chip-Seq_BREAST_Human1.03206833
80PADI4_21655091_ChIP-ChIP_MCF-7_Human1.02038769
81CTCF_18555785_ChIP-Seq_MESCs_Mouse1.01311478
82* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.99663197
83KLF4_18555785_ChIP-Seq_MESCs_Mouse0.98759146
84PHF8_20622854_ChIP-Seq_HELA_Human0.98601186
85MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.98085659
86CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97664920
87* TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.96602379
88BCL6_27268052_Chip-Seq_Bcells_Human0.95332907
89STAT3_1855785_ChIP-Seq_MESCs_Mouse0.94675013
90P68_20966046_ChIP-Seq_HELA_Human0.94567905
91CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.94410511
92SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.93071302
93MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.92611067
94AR_21909140_ChIP-Seq_LNCAP_Human0.90816484
95EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.90034457
96POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.89507303
97CTCF_26484167_Chip-Seq_Bcells_Mouse0.88881947
98SRY_22984422_ChIP-ChIP_TESTIS_Rat0.88690443
99NOTCH1_21737748_ChIP-Seq_TLL_Human0.88370610
100CIITA_25753668_ChIP-Seq_RAJI_Human0.87166770
101VDR_22108803_ChIP-Seq_LS180_Human0.87049745
102SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.86583176
103* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.86519049
104* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86257723
105KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.85561539
106KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.85561539
107KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.85561539
108SOX17_20123909_ChIP-Seq_XEN_Mouse0.85489062
109HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.84644153
110RARB_24833708_ChIP-Seq_LIVER_Mouse0.84499117
111KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.81786778
112HTT_18923047_ChIP-ChIP_STHdh_Human0.80306140
113NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.79719202
114OCT4_18692474_ChIP-Seq_MEFs_Mouse0.77081077
115FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.76018852
116SOX2_18692474_ChIP-Seq_MEFs_Mouse0.74708991
117TBX5_21415370_ChIP-Seq_HL-1_Mouse0.73937133
118CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.73541653
119FUS_26573619_Chip-Seq_HEK293_Human0.71836620
120* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71369235
121TFEB_21752829_ChIP-Seq_HELA_Human0.70535255
122EZH2_22144423_ChIP-Seq_EOC_Human0.69420045
123YY1_22570637_ChIP-Seq_MALME-3M_Human0.67997965
124NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.66925375
125FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.66638474
126TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.66202917
127* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.66098989

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis3.85542450
2MP0010094_abnormal_chromosome_stability3.77520610
3MP0001529_abnormal_vocalization3.68566694
4MP0003880_abnormal_central_pattern3.53485080
5MP0006036_abnormal_mitochondrial_physio2.95917223
6MP0002837_dystrophic_cardiac_calcinosis2.86794313
7MP0006292_abnormal_olfactory_placode2.65001941
8MP0003077_abnormal_cell_cycle2.57703677
9MP0001905_abnormal_dopamine_level2.53255072
10MP0003786_premature_aging2.49556267
11MP0009379_abnormal_foot_pigmentation2.44286752
12MP0004147_increased_porphyrin_level2.41860095
13MP0010030_abnormal_orbit_morphology2.25505414
14MP0008007_abnormal_cellular_replicative2.22392598
15MP0002736_abnormal_nociception_after2.03232974
16MP0001968_abnormal_touch/_nociception2.03198085
17MP0006035_abnormal_mitochondrial_morpho1.99237425
18MP0002272_abnormal_nervous_system1.97145909
19MP0008875_abnormal_xenobiotic_pharmacok1.93670464
20MP0006276_abnormal_autonomic_nervous1.93299554
21MP0003186_abnormal_redox_activity1.90357521
22MP0003693_abnormal_embryo_hatching1.85636302
23MP0003656_abnormal_erythrocyte_physiolo1.83620185
24MP0003718_maternal_effect1.82434246
25MP0001764_abnormal_homeostasis1.81550680
26MP0002139_abnormal_hepatobiliary_system1.72195104
27MP0008260_abnormal_autophagy1.70745155
28MP0005085_abnormal_gallbladder_physiolo1.70060962
29MP0004142_abnormal_muscle_tone1.68430832
30MP0001440_abnormal_grooming_behavior1.64516076
31MP0005670_abnormal_white_adipose1.63746821
32MP0005451_abnormal_body_composition1.62163474
33MP0002064_seizures1.61903640
34MP0002876_abnormal_thyroid_physiology1.60724510
35MP0001501_abnormal_sleep_pattern1.59847269
36MP0004270_analgesia1.58660269
37MP0005332_abnormal_amino_acid1.57791523
38MP0002938_white_spotting1.57503460
39MP0003329_amyloid_beta_deposits1.53582664
40MP0001188_hyperpigmentation1.53490304
41MP0009745_abnormal_behavioral_response1.51244063
42MP0001730_embryonic_growth_arrest1.50907171
43MP0000749_muscle_degeneration1.49469660
44MP0001666_abnormal_nutrient_absorption1.48941732
45MP0002822_catalepsy1.43005972
46MP0004957_abnormal_blastocyst_morpholog1.41864524
47MP0002653_abnormal_ependyma_morphology1.41804830
48MP0006072_abnormal_retinal_apoptosis1.38656348
49MP0004036_abnormal_muscle_relaxation1.36651418
50MP0003635_abnormal_synaptic_transmissio1.35813208
51MP0005360_urolithiasis1.34682994
52MP0000566_synostosis1.34562440
53MP0002735_abnormal_chemical_nociception1.33228714
54MP0005266_abnormal_metabolism1.29985605
55MP0004215_abnormal_myocardial_fiber1.29762119
56MP0003646_muscle_fatigue1.28640217
57MP0004859_abnormal_synaptic_plasticity1.28558761
58MP0000350_abnormal_cell_proliferation1.27951499
59MP0004145_abnormal_muscle_electrophysio1.27435408
60MP0002734_abnormal_mechanical_nocicepti1.26572077
61MP0002067_abnormal_sensory_capabilities1.25847169
62MP0002572_abnormal_emotion/affect_behav1.25321744
63MP0002210_abnormal_sex_determination1.25306429
64MP0003195_calcinosis1.25000154
65MP0004924_abnormal_behavior1.24625253
66MP0005386_behavior/neurological_phenoty1.24625253
67MP0001929_abnormal_gametogenesis1.24165347
68MP0005365_abnormal_bile_salt1.23400414
69MP0004043_abnormal_pH_regulation1.22464273
70MP0009046_muscle_twitch1.22015396
71MP0003315_abnormal_perineum_morphology1.21619698
72MP0008995_early_reproductive_senescence1.21516228
73MP0005075_abnormal_melanosome_morpholog1.20683124
74MP0002132_abnormal_respiratory_system1.18213363
75MP0000313_abnormal_cell_death1.17599469
76MP0003122_maternal_imprinting1.17411881
77MP0001970_abnormal_pain_threshold1.16462031
78MP0002733_abnormal_thermal_nociception1.15625752
79MP0009697_abnormal_copulation1.15084834
80MP0008872_abnormal_physiological_respon1.14749808
81MP0008058_abnormal_DNA_repair1.14221527
82MP0009840_abnormal_foam_cell1.12147081
83MP0001293_anophthalmia1.11365091
84MP0005058_abnormal_lysosome_morphology1.11005597
85MP0000653_abnormal_sex_gland1.10438075
86MP0003123_paternal_imprinting1.10282668
87MP0001145_abnormal_male_reproductive1.10187903
88MP0000049_abnormal_middle_ear1.09083275
89MP0008057_abnormal_DNA_replication1.07591379
90MP0001984_abnormal_olfaction1.06791415
91MP0002080_prenatal_lethality1.04796703
92MP0005408_hypopigmentation1.04138984
93MP0002063_abnormal_learning/memory/cond1.02739898
94MP0001697_abnormal_embryo_size1.02632180
95MP0001486_abnormal_startle_reflex1.02107990
96MP0005636_abnormal_mineral_homeostasis1.01146449
97MP0000678_abnormal_parathyroid_gland1.00650768
98MP0002019_abnormal_tumor_incidence0.99193432
99MP0005376_homeostasis/metabolism_phenot0.98868682
100MP0000490_abnormal_crypts_of0.98766480
101MP0003879_abnormal_hair_cell0.97996375
102MP0000230_abnormal_systemic_arterial0.96301888
103MP0005319_abnormal_enzyme/_coenzyme0.96300382
104MP0008789_abnormal_olfactory_epithelium0.95448639
105MP0000747_muscle_weakness0.94265444
106MP0001727_abnormal_embryo_implantation0.94180969
107MP0005330_cardiomyopathy0.94113495
108MP0003121_genomic_imprinting0.94096941
109MP0000751_myopathy0.93135607
110MP0010329_abnormal_lipoprotein_level0.92709760
111MP0005584_abnormal_enzyme/coenzyme_acti0.91588425
112MP0000358_abnormal_cell_content/0.91565162
113MP0001672_abnormal_embryogenesis/_devel0.90378616
114MP0005380_embryogenesis_phenotype0.90378616
115MP0008877_abnormal_DNA_methylation0.89270273
116MP0003698_abnormal_male_reproductive0.88684576
117MP0009672_abnormal_birth_weight0.87811700
118MP0000372_irregular_coat_pigmentation0.86899773
119MP0002269_muscular_atrophy0.86096024
120MP0004084_abnormal_cardiac_muscle0.85904061
121MP0003119_abnormal_digestive_system0.85649831
122MP0005535_abnormal_body_temperature0.84410641
123MP0002085_abnormal_embryonic_tissue0.83537564
124MP0001119_abnormal_female_reproductive0.83051852
125MP0003567_abnormal_fetal_cardiomyocyte0.82374951
126MP0005394_taste/olfaction_phenotype0.81561783
127MP0005499_abnormal_olfactory_system0.81561783
128MP0002229_neurodegeneration0.80604795
129MP0002233_abnormal_nose_morphology0.80317922
130MP0003938_abnormal_ear_development0.80295855
131MP0005501_abnormal_skin_physiology0.79231514
132MP0008932_abnormal_embryonic_tissue0.78631948
133MP0005084_abnormal_gallbladder_morpholo0.76980228
134MP0002066_abnormal_motor_capabilities/c0.76923997
135MP0002102_abnormal_ear_morphology0.75486481
136MP0003984_embryonic_growth_retardation0.75365450
137MP0002160_abnormal_reproductive_system0.73560254
138MP0005646_abnormal_pituitary_gland0.72980267
139MP0002638_abnormal_pupillary_reflex0.72768730
140MP0004484_altered_response_of0.72169305
141MP0004133_heterotaxia0.71733916
142MP0002234_abnormal_pharynx_morphology0.71489385
143MP0001485_abnormal_pinna_reflex0.70940399
144MP0000639_abnormal_adrenal_gland0.70536987
145MP0002088_abnormal_embryonic_growth/wei0.68881688
146MP0001661_extended_life_span0.68842424
147MP0000598_abnormal_liver_morphology0.68629312
148MP0003111_abnormal_nucleus_morphology0.68000402
149MP0002161_abnormal_fertility/fecundity0.67998695
150MP0002084_abnormal_developmental_patter0.67179327
151MP0001963_abnormal_hearing_physiology0.66640023
152MP0002557_abnormal_social/conspecific_i0.65332359
153MP0004019_abnormal_vitamin_homeostasis0.64482283
154MP0001346_abnormal_lacrimal_gland0.60877951
155MP0002751_abnormal_autonomic_nervous0.60754055
156MP0002163_abnormal_gland_morphology0.60734558
157MP0008873_increased_physiological_sensi0.60161576
158MP0001986_abnormal_taste_sensitivity0.59118194

Predicted human phenotypes

RankGene SetZ-score
1Hepatocellular necrosis (HP:0001404)5.46231661
2Acute necrotizing encephalopathy (HP:0006965)5.42298169
3Hepatic necrosis (HP:0002605)5.03125443
4Abnormal mitochondria in muscle tissue (HP:0008316)5.01117385
5Mitochondrial inheritance (HP:0001427)4.95141345
6Acute encephalopathy (HP:0006846)4.70291720
7Increased CSF lactate (HP:0002490)4.54547489
8Progressive macrocephaly (HP:0004481)4.30239111
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.17448984
10Decreased activity of mitochondrial respiratory chain (HP:0008972)4.17448984
11Increased serum pyruvate (HP:0003542)4.04109203
12Abnormality of glycolysis (HP:0004366)4.04109203
13Lactic acidosis (HP:0003128)3.73509807
14Increased serum lactate (HP:0002151)3.71060581
15Cerebral edema (HP:0002181)3.69031600
163-Methylglutaconic aciduria (HP:0003535)3.32102163
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.30578373
18Respiratory failure (HP:0002878)3.27285651
19Cerebral hypomyelination (HP:0006808)3.26392863
20Increased hepatocellular lipid droplets (HP:0006565)3.23178440
21Lipid accumulation in hepatocytes (HP:0006561)3.15070733
22Leukodystrophy (HP:0002415)3.12916274
23Hypothermia (HP:0002045)3.09025756
24Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.98602891
25Abnormal protein N-linked glycosylation (HP:0012347)2.98602891
26Abnormal protein glycosylation (HP:0012346)2.98602891
27Abnormal glycosylation (HP:0012345)2.98602891
28CNS demyelination (HP:0007305)2.97686111
29Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.97288527
30Generalized aminoaciduria (HP:0002909)2.95320289
31Renal Fanconi syndrome (HP:0001994)2.93183128
32Exercise intolerance (HP:0003546)2.91683334
33Delusions (HP:0000746)2.91517625
34Testicular atrophy (HP:0000029)2.87032545
35Lethargy (HP:0001254)2.82712112
36CNS hypomyelination (HP:0003429)2.82463046
37Multiple enchondromatosis (HP:0005701)2.82125920
38Increased intramyocellular lipid droplets (HP:0012240)2.77665780
39Emotional lability (HP:0000712)2.68919136
40Microretrognathia (HP:0000308)2.67925531
41Optic disc pallor (HP:0000543)2.65724292
42Microvesicular hepatic steatosis (HP:0001414)2.56953696
43Hypobetalipoproteinemia (HP:0003563)2.56945483
44Increased muscle lipid content (HP:0009058)2.56787108
45Abnormality of aromatic amino acid family metabolism (HP:0004338)2.55380670
46Methylmalonic aciduria (HP:0012120)2.53759792
47Dicarboxylic aciduria (HP:0003215)2.51381153
48Abnormality of dicarboxylic acid metabolism (HP:0010995)2.51381153
49Reticulocytopenia (HP:0001896)2.46508187
50Colon cancer (HP:0003003)2.45320982
51Abnormality of alanine metabolism (HP:0010916)2.42582373
52Hyperalaninemia (HP:0003348)2.42582373
53Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.42582373
54Hyperventilation (HP:0002883)2.38939896
55Reduced antithrombin III activity (HP:0001976)2.33573586
56Ependymoma (HP:0002888)2.28712866
57Aplasia/Hypoplasia of the sacrum (HP:0008517)2.26215067
58Focal motor seizures (HP:0011153)2.25109744
59Neuroendocrine neoplasm (HP:0100634)2.23255122
60Abnormality of the heme biosynthetic pathway (HP:0010472)2.19180111
61Abnormality of methionine metabolism (HP:0010901)2.18656228
62Abnormality of the labia minora (HP:0012880)2.18026798
63Abnormality of cells of the erythroid lineage (HP:0012130)2.17572076
64Progressive microcephaly (HP:0000253)2.14142017
65Progressive external ophthalmoplegia (HP:0000590)2.13774141
66Methylmalonic acidemia (HP:0002912)2.13599683
67Type I transferrin isoform profile (HP:0003642)2.12565896
68Medial flaring of the eyebrow (HP:0010747)2.10296916
69Birth length less than 3rd percentile (HP:0003561)2.07242409
70Poor suck (HP:0002033)2.06503996
71Abnormal number of erythroid precursors (HP:0012131)2.04942229
72Facial cleft (HP:0002006)2.04167760
73Respiratory difficulties (HP:0002880)2.03373245
74Cleft eyelid (HP:0000625)2.03193727
75Hypoplasia of the capital femoral epiphysis (HP:0003090)2.03089186
76Hyperglycinemia (HP:0002154)2.02838529
77Horseshoe kidney (HP:0000085)2.02166191
78Autoamputation (HP:0001218)2.01793365
79Ragged-red muscle fibers (HP:0003200)2.01394934
80Exertional dyspnea (HP:0002875)2.00353676
81Gout (HP:0001997)1.99777952
82Broad distal phalanx of finger (HP:0009836)1.98405727
83Cholecystitis (HP:0001082)1.97614393
84Abnormal gallbladder physiology (HP:0012438)1.97614393
85Unsteady gait (HP:0002317)1.97610017
86Seborrheic dermatitis (HP:0001051)1.96999489
87Pheochromocytoma (HP:0002666)1.96573826
88Vomiting (HP:0002013)1.93325246
89Abnormality of pyrimidine metabolism (HP:0004353)1.92644528
90Abnormality of the anterior horn cell (HP:0006802)1.92629831
91Degeneration of anterior horn cells (HP:0002398)1.92629831
92Abnormality of serum amino acid levels (HP:0003112)1.92176580
93Severe visual impairment (HP:0001141)1.91924001
94Gliosis (HP:0002171)1.91580123
95Prolonged partial thromboplastin time (HP:0003645)1.91508428
96Macrocytic anemia (HP:0001972)1.91413077
97X-linked dominant inheritance (HP:0001423)1.91039322
98Progressive muscle weakness (HP:0003323)1.90818358
99Abnormality of serine family amino acid metabolism (HP:0010894)1.87027624
100Abnormality of glycine metabolism (HP:0010895)1.87027624
101Spastic paraparesis (HP:0002313)1.85793998
102Meckel diverticulum (HP:0002245)1.85551124
103Rhabdomyolysis (HP:0003201)1.84728048
104Abnormality of urine glucose concentration (HP:0011016)1.80729256
105Glycosuria (HP:0003076)1.80729256
106Rough bone trabeculation (HP:0100670)1.80444233
107Postnatal microcephaly (HP:0005484)1.79496007
108Gait imbalance (HP:0002141)1.78183239
109Congenital primary aphakia (HP:0007707)1.78075892
110Vaginal fistula (HP:0004320)1.77664219
111Nephrogenic diabetes insipidus (HP:0009806)1.77086379
112Megaloblastic anemia (HP:0001889)1.76843338
113Prolonged neonatal jaundice (HP:0006579)1.76568581
114Myoglobinuria (HP:0002913)1.75917313
115Chromosomal breakage induced by crosslinking agents (HP:0003221)1.74746817
116Split foot (HP:0001839)1.74640648
117Delayed CNS myelination (HP:0002188)1.74468440
118Abnormality of renal resorption (HP:0011038)1.74116365
119Premature ovarian failure (HP:0008209)1.74030571
120Myokymia (HP:0002411)1.72904687
121Absent epiphyses (HP:0010577)1.72655556
122Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.72655556
123Epileptic encephalopathy (HP:0200134)1.72303125
124Hypoplastic pelvis (HP:0008839)1.70738547
125Optic nerve coloboma (HP:0000588)1.70093235
126Abnormality of the ileum (HP:0001549)1.69778006
127Abnormality of pain sensation (HP:0010832)1.69217640
128Impaired pain sensation (HP:0007328)1.69217640
129Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.69090427
130Metabolic acidosis (HP:0001942)1.68628861
131Hyperammonemia (HP:0001987)1.68291520
132Chromsome breakage (HP:0040012)1.67906683
133Abnormality of fatty-acid metabolism (HP:0004359)1.67503398
134Opisthotonus (HP:0002179)1.67476407
135Cerebral palsy (HP:0100021)1.66604450
136Hyperglycinuria (HP:0003108)1.66416281
137Abnormality of the preputium (HP:0100587)1.66357342
138Pancytopenia (HP:0001876)1.62120580
139Abnormal pupillary function (HP:0007686)1.61664194

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.80796176
2BUB14.36793968
3STK163.96327687
4CDK193.08384313
5MAP3K122.78388377
6CDC72.71719391
7BCKDK2.70273759
8NME12.69537872
9CASK2.68229246
10TESK22.62291782
11NME22.39104737
12EIF2AK12.31427401
13WEE12.30738187
14TESK12.26060736
15TSSK62.19993302
16PNCK1.98731174
17EIF2AK31.96867188
18MAP4K21.95264906
19ARAF1.88787393
20MAP2K71.84539041
21CCNB11.72492352
22VRK11.63881099
23MYLK1.61943777
24OXSR11.61107225
25AKT31.56976106
26TRIM281.56908155
27GRK51.47239792
28ATR1.46909786
29PLK21.39843090
30ZAK1.38822798
31NUAK11.37495544
32SCYL21.34607616
33MST41.28573661
34MAP3K41.27308253
35MAP2K21.17454042
36PDK31.17195376
37PDK41.17195376
38BRAF1.16443455
39CSNK1A1L1.11187966
40ERN11.11006509
41CDK71.10441079
42CHEK21.06612286
43PBK1.06537316
44EPHA41.06121540
45MAP2K41.03598884
46AURKB1.03511154
47TNIK1.01361598
48ILK1.00837759
49TLK11.00779172
50OBSCN0.99798220
51SMG10.95907088
52ADRBK20.95427319
53AURKA0.93264134
54NTRK30.91406440
55CHEK10.91032945
56MUSK0.90235974
57STK390.89920910
58GRK70.89906773
59BMPR20.88713792
60MAPKAPK50.88683814
61DAPK10.87116837
62RIPK40.86030523
63PLK30.85594731
64NEK10.84623042
65RPS6KA40.81707391
66PAK30.79393822
67EPHA20.78817966
68CAMK2B0.78670380
69DYRK30.78005304
70PINK10.77438254
71CSNK1G30.77281073
72BCR0.77084301
73LIMK10.76386937
74PRKCG0.76005733
75CAMK2D0.75843848
76GRK60.71762295
77RPS6KA50.68349392
78FLT30.67326940
79SIK30.67210355
80PIM20.65665076
81PDK20.65503676
82CDK40.63370851
83MKNK20.62563340
84CDK30.60018460
85PLK40.59217944
86MAP3K110.59186831
87CAMK2A0.59104430
88CSNK2A20.59060045
89MAP3K30.58120020
90KDR0.58061847
91WNK30.58034516
92DYRK20.57727756
93PAK40.56027201
94CAMK2G0.55657470
95CSNK1G20.55207973
96ATM0.54090890
97ABL20.53597088
98TAF10.53433781
99CDK20.52799196
100MAP3K20.52795074
101NEK20.50996113
102CDK140.49850351
103MAPK40.49616895
104CSNK2A10.49423713
105MINK10.49264133
106MKNK10.49138916
107PHKG10.49023185
108PHKG20.49023185
109PRKCI0.48573005
110CSNK1G10.47816715
111IRAK30.47229179
112TRIB30.43765679
113CDK11A0.43120169
114WNK40.42857484
115BRSK10.42630657
116RAF10.42092552
117CDK80.41909219
118PRKACA0.40540089
119CAMK10.40219562
120MET0.39815177
121MAPK120.39486279
122BRSK20.39469016
123SRPK10.39305161
124FGFR40.39266127
125MAPK150.38485935
126CDK180.38398583
127SYK0.37683986
128TAOK20.37423102
129CDK150.37336264
130CSNK1A10.37305754
131PLK10.36948522
132PTK2B0.36804633
133MATK0.35554082
134MAPK110.34942593
135CDK90.34928735
136FES0.34687861
137RPS6KB20.34394315
138CDK10.33940143
139TNK20.33902317
140MAP3K80.33828645
141TTK0.33199969
142PAK10.32265477
143AKT20.30982425
144BMPR1B0.29364334
145MST1R0.29299899
146STK40.29208384
147PRKD20.27623673

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.64353986
2Proteasome_Homo sapiens_hsa030504.00245573
3Parkinsons disease_Homo sapiens_hsa050123.87845543
4RNA polymerase_Homo sapiens_hsa030203.20649294
5Ribosome_Homo sapiens_hsa030102.94546756
6Alzheimers disease_Homo sapiens_hsa050102.80763774
7Huntingtons disease_Homo sapiens_hsa050162.70632284
8Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.57485587
9Protein export_Homo sapiens_hsa030602.30707663
10Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.29024192
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.07329540
12Pyrimidine metabolism_Homo sapiens_hsa002401.91905638
13Vitamin B6 metabolism_Homo sapiens_hsa007501.86627218
14Pyruvate metabolism_Homo sapiens_hsa006201.85860796
15Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.82219129
16Collecting duct acid secretion_Homo sapiens_hsa049661.79820765
17Folate biosynthesis_Homo sapiens_hsa007901.79056480
18Fatty acid elongation_Homo sapiens_hsa000621.74995986
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.73080264
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.69641783
21Fanconi anemia pathway_Homo sapiens_hsa034601.68932606
22Cardiac muscle contraction_Homo sapiens_hsa042601.67449084
23Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.58635559
24Cysteine and methionine metabolism_Homo sapiens_hsa002701.55623617
25Propanoate metabolism_Homo sapiens_hsa006401.49113558
26DNA replication_Homo sapiens_hsa030301.46088853
272-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.45370863
28Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.43741778
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.39660243
30Carbon metabolism_Homo sapiens_hsa012001.31695320
31Purine metabolism_Homo sapiens_hsa002301.24758542
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.21904280
33Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.18235481
34Mismatch repair_Homo sapiens_hsa034301.17978266
35Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.17100241
36Sulfur metabolism_Homo sapiens_hsa009201.16902114
37Butanoate metabolism_Homo sapiens_hsa006501.08593927
38Vibrio cholerae infection_Homo sapiens_hsa051101.06868709
39Drug metabolism - other enzymes_Homo sapiens_hsa009831.06825982
40Metabolic pathways_Homo sapiens_hsa011001.06000979
41Spliceosome_Homo sapiens_hsa030401.05095188
42Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.04979746
43Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.02627057
44Biosynthesis of amino acids_Homo sapiens_hsa012301.02024882
45RNA transport_Homo sapiens_hsa030131.00021793
46Glutathione metabolism_Homo sapiens_hsa004800.98986923
47Nucleotide excision repair_Homo sapiens_hsa034200.98944209
48Basal transcription factors_Homo sapiens_hsa030220.97732744
49Peroxisome_Homo sapiens_hsa041460.92650632
50Arginine biosynthesis_Homo sapiens_hsa002200.91717524
51Regulation of autophagy_Homo sapiens_hsa041400.91362193
52Galactose metabolism_Homo sapiens_hsa000520.91031333
53Fat digestion and absorption_Homo sapiens_hsa049750.90879318
54Cell cycle_Homo sapiens_hsa041100.90118612
55Base excision repair_Homo sapiens_hsa034100.88944981
56Fructose and mannose metabolism_Homo sapiens_hsa000510.87750640
57RNA degradation_Homo sapiens_hsa030180.86306903
58Synaptic vesicle cycle_Homo sapiens_hsa047210.85974965
59Nicotine addiction_Homo sapiens_hsa050330.85369916
60Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.84677398
61Primary bile acid biosynthesis_Homo sapiens_hsa001200.83571821
62Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.82320553
63Pentose phosphate pathway_Homo sapiens_hsa000300.80688457
64Non-homologous end-joining_Homo sapiens_hsa034500.79501175
65Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.78428770
66Sulfur relay system_Homo sapiens_hsa041220.75659524
67N-Glycan biosynthesis_Homo sapiens_hsa005100.74217077
68Arginine and proline metabolism_Homo sapiens_hsa003300.72718133
69Homologous recombination_Homo sapiens_hsa034400.72347695
70Fatty acid degradation_Homo sapiens_hsa000710.72099535
71Chemical carcinogenesis_Homo sapiens_hsa052040.67016793
72Fatty acid metabolism_Homo sapiens_hsa012120.65111002
73Histidine metabolism_Homo sapiens_hsa003400.61556253
74Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.61209614
75Tyrosine metabolism_Homo sapiens_hsa003500.57359008
76Glycosaminoglycan degradation_Homo sapiens_hsa005310.57330942
77Other glycan degradation_Homo sapiens_hsa005110.57055496
78Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.56943468
79mRNA surveillance pathway_Homo sapiens_hsa030150.56847406
80Linoleic acid metabolism_Homo sapiens_hsa005910.56147870
81Pentose and glucuronate interconversions_Homo sapiens_hsa000400.55397379
82Maturity onset diabetes of the young_Homo sapiens_hsa049500.54999404
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.54425516
84Retinol metabolism_Homo sapiens_hsa008300.52647884
85Primary immunodeficiency_Homo sapiens_hsa053400.52254170
86Glycerophospholipid metabolism_Homo sapiens_hsa005640.51024202
87Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.50444317
88Steroid biosynthesis_Homo sapiens_hsa001000.47390940
89Phenylalanine metabolism_Homo sapiens_hsa003600.45680978
90beta-Alanine metabolism_Homo sapiens_hsa004100.44204413
91Tryptophan metabolism_Homo sapiens_hsa003800.42394558
92One carbon pool by folate_Homo sapiens_hsa006700.40910230
93Selenocompound metabolism_Homo sapiens_hsa004500.40003908
94Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39977704
95Caffeine metabolism_Homo sapiens_hsa002320.39547339
96Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.37949830
97p53 signaling pathway_Homo sapiens_hsa041150.37221317
98Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.36922711
99Rheumatoid arthritis_Homo sapiens_hsa053230.36744479
100Lysine degradation_Homo sapiens_hsa003100.35692481
101Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.34359142
102Arachidonic acid metabolism_Homo sapiens_hsa005900.34067225
103Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33716361
104Amphetamine addiction_Homo sapiens_hsa050310.32867534
105alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.32561366
106Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.31856473
107Glycerolipid metabolism_Homo sapiens_hsa005610.31325051
108Epstein-Barr virus infection_Homo sapiens_hsa051690.31095526
109Ether lipid metabolism_Homo sapiens_hsa005650.30868293
110Cyanoamino acid metabolism_Homo sapiens_hsa004600.30073434
111Serotonergic synapse_Homo sapiens_hsa047260.29054436
112Complement and coagulation cascades_Homo sapiens_hsa046100.28365143
113Steroid hormone biosynthesis_Homo sapiens_hsa001400.28205896
114Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.27183687
115Sphingolipid metabolism_Homo sapiens_hsa006000.25179914
116PPAR signaling pathway_Homo sapiens_hsa033200.25153500
117Systemic lupus erythematosus_Homo sapiens_hsa053220.23106298
118Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.22364774
119Vitamin digestion and absorption_Homo sapiens_hsa049770.21933299
120Oocyte meiosis_Homo sapiens_hsa041140.21249105

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