MTMR6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)4.17979534
2synaptic vesicle exocytosis (GO:0016079)4.15222676
3regulation of synaptic vesicle exocytosis (GO:2000300)4.13690273
4neutrophil mediated immunity (GO:0002446)3.81232254
5regulation of short-term neuronal synaptic plasticity (GO:0048172)3.76875994
6neuronal action potential propagation (GO:0019227)3.70248813
7glutamate secretion (GO:0014047)3.66634237
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.66021576
9regulation of synaptic vesicle transport (GO:1902803)3.58154450
10cellular extravasation (GO:0045123)3.57775241
11positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.54760138
12myeloid leukocyte mediated immunity (GO:0002444)3.40504779
13pyrimidine nucleobase catabolic process (GO:0006208)3.34727472
14synaptic vesicle docking involved in exocytosis (GO:0016081)3.32029798
15retrograde transport, vesicle recycling within Golgi (GO:0000301)3.30664982
16locomotory exploration behavior (GO:0035641)3.29181037
17positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.23761328
18proline transport (GO:0015824)3.23150895
19vocalization behavior (GO:0071625)3.22442886
20detection of molecule of bacterial origin (GO:0032490)3.20082972
21regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.18832197
22protein localization to synapse (GO:0035418)3.12451692
23protein localization to endosome (GO:0036010)3.08570255
24neuron cell-cell adhesion (GO:0007158)3.07892627
25activation of protein kinase A activity (GO:0034199)3.07506460
26calcium ion-dependent exocytosis (GO:0017156)3.05375068
27Golgi to endosome transport (GO:0006895)3.05088228
28membrane depolarization during action potential (GO:0086010)3.00544448
29neurotransmitter secretion (GO:0007269)3.00152936
30regulation of synapse structural plasticity (GO:0051823)2.99862826
31negative regulation of dendrite morphogenesis (GO:0050774)2.96681304
32membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.94931287
33regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.94526260
34regulation of glutamate receptor signaling pathway (GO:1900449)2.93467123
35vesicle transport along microtubule (GO:0047496)2.90836579
36cellular potassium ion homeostasis (GO:0030007)2.90312279
37response to peptidoglycan (GO:0032494)2.90241653
38neurofilament cytoskeleton organization (GO:0060052)2.90101556
39nerve growth factor signaling pathway (GO:0038180)2.89810096
40macrophage activation involved in immune response (GO:0002281)2.87475063
41positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.83822131
42negative regulation of interleukin-12 production (GO:0032695)2.81763609
43intra-Golgi vesicle-mediated transport (GO:0006891)2.80658416
44response to nerve growth factor (GO:1990089)2.80278919
45cellular response to nerve growth factor stimulus (GO:1990090)2.80278919
46negative regulation of interleukin-17 production (GO:0032700)2.79532752
47neutrophil activation involved in immune response (GO:0002283)2.76326464
48regulation of neuronal synaptic plasticity (GO:0048168)2.75483103
49exploration behavior (GO:0035640)2.75053290
50positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.73724968
51phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.71529506
52activated T cell proliferation (GO:0050798)2.71300849
53macrophage activation (GO:0042116)2.70481774
54positive regulation by organism of defense response of other organism involved in symbiotic interact2.69982268
55modulation by symbiont of host immune response (GO:0052553)2.69982268
56positive regulation by symbiont of host defense response (GO:0052509)2.69982268
57modulation by symbiont of host defense response (GO:0052031)2.69982268
58modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.69982268
59modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.69982268
60acrosome reaction (GO:0007340)2.65823979
61cellular response to ethanol (GO:0071361)2.65642724
62regulation of voltage-gated calcium channel activity (GO:1901385)2.65036438
63detection of temperature stimulus involved in sensory perception (GO:0050961)2.64418749
64detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.64418749
65negative regulation of inclusion body assembly (GO:0090084)2.63924936
66negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.63327322
67regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.63220635
68nucleobase catabolic process (GO:0046113)2.62730747
69protein targeting to vacuole (GO:0006623)2.61976266
70protein targeting to lysosome (GO:0006622)2.61976266
71establishment of protein localization to vacuole (GO:0072666)2.61976266
72organelle transport along microtubule (GO:0072384)2.61599513
73regulation of interferon-beta biosynthetic process (GO:0045357)2.61275964
74early endosome to late endosome transport (GO:0045022)2.59471199
75regulation of neurotransmitter secretion (GO:0046928)2.57463720
76establishment of nucleus localization (GO:0040023)2.55695246
77positive regulation of mitochondrial fission (GO:0090141)2.54782963
78ionotropic glutamate receptor signaling pathway (GO:0035235)2.53228566
79neural tube formation (GO:0001841)2.52129337
80neurotransmitter transport (GO:0006836)2.51293552
81gamma-aminobutyric acid signaling pathway (GO:0007214)2.50760333
82axon cargo transport (GO:0008088)2.49722390
83regulation of vesicle fusion (GO:0031338)2.48758417
84cerebellar Purkinje cell differentiation (GO:0021702)2.48679324
85regulation of long-term neuronal synaptic plasticity (GO:0048169)2.48624547
86macroautophagy (GO:0016236)2.48458729
87axonal fasciculation (GO:0007413)2.48156496
88regulation of ARF protein signal transduction (GO:0032012)2.47837480
89endoplasmic reticulum organization (GO:0007029)2.46991111
90interferon-gamma production (GO:0032609)2.46065168
91negative regulation of NF-kappaB import into nucleus (GO:0042347)2.45533551
92dendrite morphogenesis (GO:0048813)2.45475870
93detection of temperature stimulus (GO:0016048)2.44244923
94positive regulation of cellular amide metabolic process (GO:0034250)2.43605149
95membrane depolarization (GO:0051899)2.43468993
96transferrin transport (GO:0033572)2.42601192
97negative regulation of synaptic transmission, GABAergic (GO:0032229)2.42197011
98regulation of amyloid precursor protein catabolic process (GO:1902991)2.41818850
99regulation of synaptic transmission, glutamatergic (GO:0051966)2.41631756
100sodium ion export (GO:0071436)2.41393379
101regulation of excitatory postsynaptic membrane potential (GO:0060079)2.39951024
102potassium ion import (GO:0010107)2.39850260
103response to acidic pH (GO:0010447)2.39185256
104ribonucleoprotein complex disassembly (GO:0032988)2.38818273
105neuron-neuron synaptic transmission (GO:0007270)2.37976661
106negative regulation of neurotransmitter transport (GO:0051589)2.37458308
107presynaptic membrane assembly (GO:0097105)2.36563932
108neurotransmitter-gated ion channel clustering (GO:0072578)2.35417176
109neuromuscular process controlling posture (GO:0050884)2.34686914
110regulation of neurotransmitter transport (GO:0051588)2.34528270
111clathrin coat assembly (GO:0048268)2.34271790
112long-term synaptic potentiation (GO:0060291)2.33948233
113mating behavior (GO:0007617)2.33870502
114regulation of synaptic plasticity (GO:0048167)2.33818083
115positive regulation of synaptic transmission, GABAergic (GO:0032230)2.33680987
116neuromuscular process controlling balance (GO:0050885)2.32685216
117positive regulation of potassium ion transport (GO:0043268)2.32583047
118positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.32482957
119protein targeting to Golgi (GO:0000042)2.32237089
120positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.31881230
121gamma-aminobutyric acid transport (GO:0015812)2.31109034
122positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.31064109
123energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.30964761
124ATP hydrolysis coupled proton transport (GO:0015991)2.30964761
125synaptic vesicle endocytosis (GO:0048488)2.30228337
126negative regulation of dendrite development (GO:2000171)2.30190177
127phospholipid translocation (GO:0045332)2.29848200
128lipid translocation (GO:0034204)2.29848200
129positive regulation of membrane potential (GO:0045838)2.28767247
130negative regulation of neurotransmitter secretion (GO:0046929)2.28531749
131positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.28048617
132mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.28048617
133phagosome maturation (GO:0090382)2.27958239
134negative regulation of cell killing (GO:0031342)2.27699069
135negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.27699069
136microglial cell activation (GO:0001774)2.26831272
137COPII vesicle coating (GO:0048208)2.26594298
138cilium or flagellum-dependent cell motility (GO:0001539)2.26570102
139ferric iron transport (GO:0015682)2.26421601
140trivalent inorganic cation transport (GO:0072512)2.26421601
141synaptic transmission, glutamatergic (GO:0035249)2.26238195
142layer formation in cerebral cortex (GO:0021819)2.26209307
143innervation (GO:0060384)2.25905980
144regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.25874353
145presynaptic membrane organization (GO:0097090)2.25655893
146regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.25441567
147glutamate receptor signaling pathway (GO:0007215)2.25278729
148establishment of vesicle localization (GO:0051650)2.24952627
149neuron recognition (GO:0008038)2.24835938
150regulation of postsynaptic membrane potential (GO:0060078)2.24467511
151synaptic vesicle transport (GO:0048489)2.24434961
152establishment of synaptic vesicle localization (GO:0097480)2.24434961
153cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.24317136
154glycine transport (GO:0015816)2.24156373
155establishment of protein localization to Golgi (GO:0072600)2.24067141
156L-amino acid import (GO:0043092)2.24006779
157regulation of neurotransmitter levels (GO:0001505)2.23947378
158neutrophil activation (GO:0042119)2.23151678
159histamine secretion (GO:0001821)2.23136027
160positive regulation of fibroblast migration (GO:0010763)2.20770233
161protein localization to Golgi apparatus (GO:0034067)2.19371658
162granulocyte activation (GO:0036230)2.15559763
163regulation of beta-amyloid formation (GO:1902003)2.15421533
164positive regulation of gamma-delta T cell activation (GO:0046645)2.14579921
165response to lipoprotein particle (GO:0055094)2.14502359
166regulation of clathrin-mediated endocytosis (GO:2000369)2.12548804
167ganglion development (GO:0061548)2.11841838
168vesicle localization (GO:0051648)2.11521939
169detection of other organism (GO:0098543)2.09617259
170response to muramyl dipeptide (GO:0032495)2.08805026
171detection of external biotic stimulus (GO:0098581)2.08177667
172cell adhesion mediated by integrin (GO:0033627)2.07454209
173regulation of cAMP-dependent protein kinase activity (GO:2000479)2.07409442
174vesicle coating (GO:0006901)2.06923913
175neutrophil chemotaxis (GO:0030593)2.05999184
176production of molecular mediator involved in inflammatory response (GO:0002532)2.05124509
177regulation of MHC class II biosynthetic process (GO:0045346)2.04810803
178positive regulation of leukocyte degranulation (GO:0043302)2.03924416
179positive regulation of regulated secretory pathway (GO:1903307)2.03056972
180neuronal ion channel clustering (GO:0045161)2.02351719
181regulation of mitochondrial depolarization (GO:0051900)2.02114103
182respiratory burst (GO:0045730)2.01679007
183cell wall macromolecule catabolic process (GO:0016998)2.00437867
184neutrophil migration (GO:1990266)1.99896570

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.86830961
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.15534430
3GBX2_23144817_ChIP-Seq_PC3_Human2.90792873
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.38070675
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.30628035
6SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.11542693
7MTF2_20144788_ChIP-Seq_MESCs_Mouse2.06874508
8WT1_19549856_ChIP-ChIP_CCG9911_Human2.04577598
9REST_21632747_ChIP-Seq_MESCs_Mouse2.02736336
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.99788448
11TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.96847013
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.93848539
13STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.93255604
14SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.93212174
15JARID2_20064375_ChIP-Seq_MESCs_Mouse1.92332608
16TAF15_26573619_Chip-Seq_HEK293_Human1.92249795
17IRF8_27001747_Chip-Seq_BMDM_Mouse1.87874815
18DROSHA_22980978_ChIP-Seq_HELA_Human1.87001492
19* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.85472688
20RNF2_18974828_ChIP-Seq_MESCs_Mouse1.82293881
21EZH2_18974828_ChIP-Seq_MESCs_Mouse1.82293881
22SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.77892530
23RARB_27405468_Chip-Seq_BRAIN_Mouse1.74627162
24NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.73450959
25JARID2_20075857_ChIP-Seq_MESCs_Mouse1.70662898
26CDX2_19796622_ChIP-Seq_MESCs_Mouse1.68946612
27IRF8_21731497_ChIP-ChIP_J774_Mouse1.66789929
28SUZ12_27294783_Chip-Seq_ESCs_Mouse1.65348902
29SMAD4_21799915_ChIP-Seq_A2780_Human1.64070362
30SMAD_19615063_ChIP-ChIP_OVARY_Human1.63562291
31FLI1_27457419_Chip-Seq_LIVER_Mouse1.60070221
32NR3C1_23031785_ChIP-Seq_PC12_Mouse1.59823528
33SALL1_21062744_ChIP-ChIP_HESCs_Human1.59582149
34REST_18959480_ChIP-ChIP_MESCs_Mouse1.58956170
35ZFP57_27257070_Chip-Seq_ESCs_Mouse1.58371927
36MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.57390036
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.57016350
38EZH2_27294783_Chip-Seq_ESCs_Mouse1.55904661
39MYB_21317192_ChIP-Seq_ERMYB_Mouse1.55437952
40RNF2_27304074_Chip-Seq_ESCs_Mouse1.51532036
41EGR1_19374776_ChIP-ChIP_THP-1_Human1.51219907
42STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.51204088
43EZH2_27304074_Chip-Seq_ESCs_Mouse1.50059873
44* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.49635893
45GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.49142334
46PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49068554
47BP1_19119308_ChIP-ChIP_Hs578T_Human1.46923273
48GATA2_21666600_ChIP-Seq_HMVEC_Human1.45942253
49IGF1R_20145208_ChIP-Seq_DFB_Human1.45923513
50FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43665558
51OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41934534
52AR_21572438_ChIP-Seq_LNCaP_Human1.41134342
53PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.40373805
54GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38534149
55P300_19829295_ChIP-Seq_ESCs_Human1.37861028
56EED_16625203_ChIP-ChIP_MESCs_Mouse1.37382565
57PCGF2_27294783_Chip-Seq_ESCs_Mouse1.37040163
58IKZF1_21737484_ChIP-ChIP_HCT116_Human1.36952999
59IRF8_22096565_ChIP-ChIP_GC-B_Human1.36507111
60EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.36333694
61RUNX_20019798_ChIP-Seq_JUKART_Human1.33847232
62POU3F2_20337985_ChIP-ChIP_501MEL_Human1.33569537
63CMYC_18555785_Chip-Seq_ESCs_Mouse1.33434608
64SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33395063
65VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.33238749
66SUZ12_27294783_Chip-Seq_NPCs_Mouse1.32952666
67BRD4_25478319_ChIP-Seq_HGPS_Human1.32132178
68SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.31355665
69NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.31089073
70AR_25329375_ChIP-Seq_VCAP_Human1.30716307
71EZH2_27294783_Chip-Seq_NPCs_Mouse1.30371699
72E2F1_18555785_Chip-Seq_ESCs_Mouse1.28636446
73NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.28402238
74CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.28006609
75BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.27419004
76CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.27222480
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.27040616
78MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.26852853
79TOP2B_26459242_ChIP-Seq_MCF-7_Human1.26684344
80* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26258614
81RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.25009825
82CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.25005673
83PIAS1_25552417_ChIP-Seq_VCAP_Human1.24732165
84FUS_26573619_Chip-Seq_HEK293_Human1.24596057
85P53_22387025_ChIP-Seq_ESCs_Mouse1.24254985
86VDR_22108803_ChIP-Seq_LS180_Human1.22859137
87STAT3_23295773_ChIP-Seq_U87_Human1.22112678
88SMAD3_21741376_ChIP-Seq_EPCs_Human1.21632485
89RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.21476163
90ZNF274_21170338_ChIP-Seq_K562_Hela1.19957483
91SUZ12_18555785_Chip-Seq_ESCs_Mouse1.19049236
92SOX2_21211035_ChIP-Seq_LN229_Gbm1.18813973
93ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.18079752
94ZNF217_24962896_ChIP-Seq_MCF-7_Human1.17370989
95PCGF2_27294783_Chip-Seq_NPCs_Mouse1.15935138
96ER_23166858_ChIP-Seq_MCF-7_Human1.14948181
97TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.13392885
98TP63_23658742_ChIP-Seq_EP156T_Human1.12653484
99Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.12241851
100ARNT_22903824_ChIP-Seq_MCF-7_Human1.12028137
101NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.11942277
102NRF2_20460467_ChIP-Seq_MEFs_Mouse1.11942277
103FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.10676698
104EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.10570651
105CJUN_26792858_Chip-Seq_BT549_Human1.10531410
106EWS_26573619_Chip-Seq_HEK293_Human1.09689503
107AHR_22903824_ChIP-Seq_MCF-7_Human1.08737167
108TCF4_23295773_ChIP-Seq_U87_Human1.08427118
109NFE2_27457419_Chip-Seq_LIVER_Mouse1.06814576
110P300_18555785_Chip-Seq_ESCs_Mouse1.06276462
111BCAT_22108803_ChIP-Seq_LS180_Human1.05394474
112TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.04988669
113ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.04751024
114TCF4_18268006_ChIP-ChIP_LS174T_Human1.04721489
115TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.04520218
116TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04211318
117PRDM14_20953172_ChIP-Seq_ESCs_Human1.03880584
118SALL4_18804426_ChIP-ChIP_XEN_Mouse1.03781577
119OCT4_21477851_ChIP-Seq_ESCs_Mouse1.03063297
120CRX_20693478_ChIP-Seq_RETINA_Mouse1.02991244
121PU_27001747_Chip-Seq_BMDM_Mouse1.02278952
122TP53_16413492_ChIP-PET_HCT116_Human1.01916645
123WT1_25993318_ChIP-Seq_PODOCYTE_Human1.01882789
124SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01343660
125TAL1_26923725_Chip-Seq_HPCs_Mouse1.00171946
126KDM2B_26808549_Chip-Seq_REH_Human0.99062521
127TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.98818571
128UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98794232
129EP300_21415370_ChIP-Seq_HL-1_Mouse0.98040351
130MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.97273977
131NANOG_18555785_Chip-Seq_ESCs_Mouse0.96011140
132SMAD3_21741376_ChIP-Seq_ESCs_Human0.94348600
133EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.92544149
134SMAD4_21741376_ChIP-Seq_EPCs_Human0.92366367
135RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.92334838
136FLI1_21867929_ChIP-Seq_TH2_Mouse0.92161218
137TP53_18474530_ChIP-ChIP_U2OS_Human0.91977037
138BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.91817765
139MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91603332
140AR_19668381_ChIP-Seq_PC3_Human0.90128419
141P53_22127205_ChIP-Seq_FIBROBLAST_Human0.89828306
142VDR_24787735_ChIP-Seq_THP-1_Human0.89740270
143CBP_20019798_ChIP-Seq_JUKART_Human0.89420130
144IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.89420130
145TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.89111057
146TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.88716887
147RUNX2_22187159_ChIP-Seq_PCA_Human0.88365563
148CBX2_27304074_Chip-Seq_ESCs_Mouse0.87914270
149PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.87248223
150NR3C1_21868756_ChIP-Seq_MCF10A_Human0.87237971
151BMI1_23680149_ChIP-Seq_NPCS_Mouse0.86608629
152NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.83583620

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.55706489
2MP0004270_analgesia3.89351609
3MP0003880_abnormal_central_pattern3.67043567
4MP0003724_increased_susceptibility_to3.48296790
5MP0003635_abnormal_synaptic_transmissio3.14992933
6MP0002735_abnormal_chemical_nociception3.12922617
7MP0001968_abnormal_touch/_nociception3.11738431
8MP0009046_muscle_twitch2.83866671
9MP0002736_abnormal_nociception_after2.75695865
10MP0002734_abnormal_mechanical_nocicepti2.68901244
11MP0002064_seizures2.68171660
12MP0009745_abnormal_behavioral_response2.58892739
13MP0002063_abnormal_learning/memory/cond2.54868255
14MP0003787_abnormal_imprinting2.48781872
15MP0002009_preneoplasia2.44546056
16MP0005410_abnormal_fertilization2.38613360
17MP0004858_abnormal_nervous_system2.37828917
18MP0003329_amyloid_beta_deposits2.29039110
19MP0002272_abnormal_nervous_system2.28947321
20MP0008877_abnormal_DNA_methylation2.27820548
21MP0003221_abnormal_cardiomyocyte_apopto2.27402933
22MP0002733_abnormal_thermal_nociception2.24085011
23MP0001970_abnormal_pain_threshold2.20628277
24MP0003828_pulmonary_edema2.14626460
25MP0002822_catalepsy2.14211313
26MP0006276_abnormal_autonomic_nervous2.13692952
27MP0002572_abnormal_emotion/affect_behav2.12724736
28MP0006054_spinal_hemorrhage2.12693150
29MP0002332_abnormal_exercise_endurance2.11299284
30MP0000465_gastrointestinal_hemorrhage1.96989827
31MP0001501_abnormal_sleep_pattern1.94191861
32MP0003191_abnormal_cellular_cholesterol1.93851641
33MP0009780_abnormal_chondrocyte_physiolo1.90674401
34MP0001486_abnormal_startle_reflex1.86167024
35MP0010234_abnormal_vibrissa_follicle1.86023052
36MP0003183_abnormal_peptide_metabolism1.85023969
37MP0002067_abnormal_sensory_capabilities1.82988851
38MP0003436_decreased_susceptibility_to1.81289549
39MP0006082_CNS_inflammation1.80838105
40MP0000920_abnormal_myelination1.80736647
41MP0002909_abnormal_adrenal_gland1.77699267
42MP0003633_abnormal_nervous_system1.74980941
43MP0000604_amyloidosis1.74605022
44MP0001440_abnormal_grooming_behavior1.70677024
45MP0008569_lethality_at_weaning1.65342844
46MP0004811_abnormal_neuron_physiology1.60995349
47MP0002419_abnormal_innate_immunity1.58655789
48MP0001835_abnormal_antigen_presentation1.57455346
49MP0008260_abnormal_autophagy1.56315027
50MP0005386_behavior/neurological_phenoty1.52465436
51MP0004924_abnormal_behavior1.52465436
52MP0003690_abnormal_glial_cell1.51273832
53MP0005423_abnormal_somatic_nervous1.50110039
54MP0002877_abnormal_melanocyte_morpholog1.47749116
55MP0010386_abnormal_urinary_bladder1.47366429
56MP0000013_abnormal_adipose_tissue1.47076415
57MP0002184_abnormal_innervation1.39025754
58MP0000955_abnormal_spinal_cord1.36790885
59MP0003631_nervous_system_phenotype1.35923265
60MP0003634_abnormal_glial_cell1.34711518
61MP0003879_abnormal_hair_cell1.34533305
62MP0003091_abnormal_cell_migration1.34094009
63MP0005058_abnormal_lysosome_morphology1.33995292
64MP0000569_abnormal_digit_pigmentation1.32421657
65MP0001984_abnormal_olfaction1.32021500
66MP0002102_abnormal_ear_morphology1.29203590
67MP0003172_abnormal_lysosome_physiology1.28498717
68MP0000778_abnormal_nervous_system1.28391889
69MP0010352_gastrointestinal_tract_polyps1.27983770
70MP0005000_abnormal_immune_tolerance1.27087208
71MP0003075_altered_response_to1.24456674
72MP0009785_altered_susceptibility_to1.22579071
73MP0004883_abnormal_blood_vessel1.21882129
74MP0002837_dystrophic_cardiac_calcinosis1.21868869
75MP0009764_decreased_sensitivity_to1.19402698
76MP0002066_abnormal_motor_capabilities/c1.18526332
77MP0001542_abnormal_bone_strength1.18303801
78MP0001905_abnormal_dopamine_level1.17856193
79MP0002229_neurodegeneration1.17652099
80MP0005623_abnormal_meninges_morphology1.14546339
81MP0002882_abnormal_neuron_morphology1.13273141
82MP0005535_abnormal_body_temperature1.12462562
83MP0001986_abnormal_taste_sensitivity1.12445556
84MP0001188_hyperpigmentation1.11602362
85MP0002557_abnormal_social/conspecific_i1.11327465
86MP0003303_peritoneal_inflammation1.09078548
87MP0001502_abnormal_circadian_rhythm1.07583903
88MP0002998_abnormal_bone_remodeling1.07488502
89MP0002148_abnormal_hypersensitivity_rea1.07281996
90MP0002166_altered_tumor_susceptibility1.07262800
91MP0005646_abnormal_pituitary_gland1.04892833
92MP0004885_abnormal_endolymph1.03510284
93MP0004510_myositis1.02428159
94MP0001533_abnormal_skeleton_physiology1.02135297
95MP0002006_tumorigenesis1.01871713
96MP0000427_abnormal_hair_cycle1.00853570
97MP0000751_myopathy1.00349346
98MP0003279_aneurysm1.00152325
99MP0004130_abnormal_muscle_cell0.98269442
100MP0002452_abnormal_antigen_presenting0.95240337
101MP0001348_abnormal_lacrimal_gland0.94711195
102MP0001529_abnormal_vocalization0.94183027
103MP0005164_abnormal_response_to0.90005984
104MP0005025_abnormal_response_to0.89888483
105MP0004043_abnormal_pH_regulation0.89466997
106MP0003045_fibrosis0.89232019
107MP0002723_abnormal_immune_serum0.88871112
108MP0003656_abnormal_erythrocyte_physiolo0.87579890
109MP0008995_early_reproductive_senescence0.86157564
110MP0004142_abnormal_muscle_tone0.85141958
111MP0003632_abnormal_nervous_system0.84831939
112MP0008874_decreased_physiological_sensi0.84422381
113MP0002420_abnormal_adaptive_immunity0.84205563
114MP0001915_intracranial_hemorrhage0.83798692
115MP0001845_abnormal_inflammatory_respons0.83134180
116MP0001819_abnormal_immune_cell0.82623379
117MP0002090_abnormal_vision0.82355970
118MP0004036_abnormal_muscle_relaxation0.81616639
119MP0003121_genomic_imprinting0.81179945
120MP0004742_abnormal_vestibular_system0.81123528
121MP0004947_skin_inflammation0.81020067
122MP0008004_abnormal_stomach_pH0.80612496
123MP0003566_abnormal_cell_adhesion0.79559254
124MP0003448_altered_tumor_morphology0.78986608
125MP0002928_abnormal_bile_duct0.78970141
126MP0010678_abnormal_skin_adnexa0.78579924
127MP0000015_abnormal_ear_pigmentation0.77298960
128MP0001800_abnormal_humoral_immune0.77101393
129MP0001790_abnormal_immune_system0.76773327
130MP0005387_immune_system_phenotype0.76773327
131MP0001851_eye_inflammation0.76123536
132MP0005367_renal/urinary_system_phenotyp0.74776262
133MP0000516_abnormal_urinary_system0.74776262
134MP0005167_abnormal_blood-brain_barrier0.74361546
135MP0005645_abnormal_hypothalamus_physiol0.74164581
136MP0002405_respiratory_system_inflammati0.73290500
137MP0009840_abnormal_foam_cell0.73273352
138MP0005310_abnormal_salivary_gland0.72824280
139MP0005084_abnormal_gallbladder_morpholo0.71185473
140MP0001765_abnormal_ion_homeostasis0.70783520
141MP0005166_decreased_susceptibility_to0.69456563
142MP0001299_abnormal_eye_distance/0.68818080
143MP0005171_absent_coat_pigmentation0.68630346
144MP0004145_abnormal_muscle_electrophysio0.66737126
145MP0002069_abnormal_eating/drinking_beha0.64974405
146MP0003698_abnormal_male_reproductive0.63093191
147MP0004484_altered_response_of0.63088626
148MP0002152_abnormal_brain_morphology0.61074062
149MP0004085_abnormal_heartbeat0.60977323
150MP0001963_abnormal_hearing_physiology0.60358813
151MP0008961_abnormal_basal_metabolism0.60196673
152MP0000747_muscle_weakness0.59741836
153MP0001177_atelectasis0.58751342
154MP0004147_increased_porphyrin_level0.55515533
155MP0002876_abnormal_thyroid_physiology0.55389104
156MP0003300_gastrointestinal_ulcer0.53425805
157MP0000230_abnormal_systemic_arterial0.53398641
158MP0001664_abnormal_digestion0.53272064
159MP0005551_abnormal_eye_electrophysiolog0.51579520
160MP0002693_abnormal_pancreas_physiology0.50209358

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.36071138
2Myokymia (HP:0002411)4.97252100
3Atonic seizures (HP:0010819)4.29024813
4Focal seizures (HP:0007359)4.19708223
5Supranuclear gaze palsy (HP:0000605)4.16970707
6Visual hallucinations (HP:0002367)3.80477030
7Action tremor (HP:0002345)3.74505626
8Neurofibrillary tangles (HP:0002185)3.58123965
9Pheochromocytoma (HP:0002666)3.54968438
10Epileptic encephalopathy (HP:0200134)3.38375362
11Febrile seizures (HP:0002373)3.35303031
12Termporal pattern (HP:0011008)3.33979377
13Insidious onset (HP:0003587)3.33979377
14Absence seizures (HP:0002121)3.24739210
15Tetraparesis (HP:0002273)3.24397762
16Stomatitis (HP:0010280)3.23880906
17Ankle clonus (HP:0011448)3.16744622
18Progressive cerebellar ataxia (HP:0002073)3.15750314
19Ulnar claw (HP:0001178)3.14872322
20Neuroendocrine neoplasm (HP:0100634)3.14787502
21Curly hair (HP:0002212)3.12545712
22Papillary thyroid carcinoma (HP:0002895)3.11316783
23Dynein arm defect of respiratory motile cilia (HP:0012255)3.04492167
24Absent/shortened dynein arms (HP:0200106)3.04492167
25Dialeptic seizures (HP:0011146)3.03295978
26Cerebral inclusion bodies (HP:0100314)3.02549714
27Recurrent bacterial skin infections (HP:0005406)2.90975776
28Truncal ataxia (HP:0002078)2.89555906
29Generalized tonic-clonic seizures (HP:0002069)2.87802665
30Disinhibition (HP:0000734)2.86808068
31Hematochezia (HP:0002573)2.82946480
32Papilledema (HP:0001085)2.79400023
33Eczematoid dermatitis (HP:0000976)2.77924790
34Progressive inability to walk (HP:0002505)2.70052374
35Thyroid carcinoma (HP:0002890)2.67857303
36Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.65987576
37Recurrent abscess formation (HP:0002722)2.63594291
38Abnormality of the corticospinal tract (HP:0002492)2.60205121
39Depression (HP:0000716)2.59958638
40Gaze-evoked nystagmus (HP:0000640)2.58329197
41Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.57845407
42Degeneration of the lateral corticospinal tracts (HP:0002314)2.57845407
43Abnormal eating behavior (HP:0100738)2.55684507
44Spastic gait (HP:0002064)2.52174076
45Urinary bladder sphincter dysfunction (HP:0002839)2.51386301
46Retrobulbar optic neuritis (HP:0100654)2.50825266
47Optic neuritis (HP:0100653)2.50825266
48Absent speech (HP:0001344)2.50598876
49Segmental peripheral demyelination/remyelination (HP:0003481)2.50223394
50Abnormality of macrophages (HP:0004311)2.47367503
51Postural instability (HP:0002172)2.47003510
52Neuronal loss in central nervous system (HP:0002529)2.46960089
53Excessive salivation (HP:0003781)2.45215286
54Impaired vibration sensation in the lower limbs (HP:0002166)2.44871819
55Urinary urgency (HP:0000012)2.44345293
56Drooling (HP:0002307)2.43518996
57Mutism (HP:0002300)2.42278796
58Dysmetria (HP:0001310)2.41171732
59Orchitis (HP:0100796)2.37108849
60Inappropriate behavior (HP:0000719)2.36619020
61Onion bulb formation (HP:0003383)2.36481021
62Abnormality of the musculature of the pelvis (HP:0001469)2.36279761
63Abnormality of the hip-girdle musculature (HP:0001445)2.36279761
64Abnormality of liposaccharide metabolism (HP:0010968)2.34906117
65Abnormality of glycosphingolipid metabolism (HP:0004343)2.34906117
66Abnormality of glycolipid metabolism (HP:0010969)2.34906117
67Intention tremor (HP:0002080)2.32130660
68Lower limb muscle weakness (HP:0007340)2.29438464
69Bladder carcinoma (HP:0002862)2.28216417
70Bladder neoplasm (HP:0009725)2.28216417
71Increased cerebral lipofuscin (HP:0011813)2.26333320
72Diminished motivation (HP:0000745)2.25981786
73Hypothermia (HP:0002045)2.25970246
74Transitional cell carcinoma of the bladder (HP:0006740)2.24269650
75Hypercortisolism (HP:0001578)2.24128465
76Akinesia (HP:0002304)2.22916089
77Myositis (HP:0100614)2.19536414
78Amblyopia (HP:0000646)2.19435976
79Hip dysplasia (HP:0001385)2.19416163
80Anxiety (HP:0000739)2.18746833
81Agitation (HP:0000713)2.18478670
82Episodic fever (HP:0001954)2.18132458
83Abnormality of the lower motor neuron (HP:0002366)2.15591084
84Neoplasm of the tracheobronchial system (HP:0100552)2.13922818
85Failure to thrive in infancy (HP:0001531)2.13617955
86Resting tremor (HP:0002322)2.12793575
87Testicular neoplasm (HP:0010788)2.12561797
88Atrophy/Degeneration involving motor neurons (HP:0007373)2.10884547
89Loss of speech (HP:0002371)2.10198854
90Cerebral hemorrhage (HP:0001342)2.10018897
91Subacute progressive viral hepatitis (HP:0006572)2.08326870
92Abnormal hair whorl (HP:0010721)2.07730444
93Diplopia (HP:0000651)2.06362772
94Abnormality of binocular vision (HP:0011514)2.06362772
95Amyotrophic lateral sclerosis (HP:0007354)2.06128524
96Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.04144138
97Increased CSF protein (HP:0002922)2.03613300
98Rapidly progressive (HP:0003678)2.02671382
99Abnormal respiratory motile cilium physiology (HP:0012261)2.01544062
100Decreased motor nerve conduction velocity (HP:0003431)2.01353797
101Bilateral sensorineural hearing impairment (HP:0008619)2.00974640
102Recurrent gram-negative bacterial infections (HP:0005420)2.00562382
103Hammertoe (HP:0001765)1.99388128
104Spontaneous hematomas (HP:0007420)1.99321457
105Hyperventilation (HP:0002883)1.98020934
106Autoamputation (HP:0001218)1.98014682
107Polyphagia (HP:0002591)1.97461061
108Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.96353765
109Limb dystonia (HP:0002451)1.96100590
110Dysdiadochokinesis (HP:0002075)1.94776154
111Bradykinesia (HP:0002067)1.94392471
112Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.94383913
113Neoplasm of the peripheral nervous system (HP:0100007)1.93740907
114Poor eye contact (HP:0000817)1.93617367
115Scanning speech (HP:0002168)1.91154455
116J-shaped sella turcica (HP:0002680)1.90130363
117Retinal atrophy (HP:0001105)1.87423331
118Epileptiform EEG discharges (HP:0011182)1.87113356
119Apathy (HP:0000741)1.86232502
120Dysostosis multiplex (HP:0000943)1.85932541
121Axonal loss (HP:0003447)1.85548351
122Sensory axonal neuropathy (HP:0003390)1.85126876
123Abnormality of saccadic eye movements (HP:0000570)1.84026232
124Distal sensory impairment (HP:0002936)1.83638471
125Thick nail (HP:0001805)1.83457759
126Gait ataxia (HP:0002066)1.83197342
127Abnormality of salivation (HP:0100755)1.82385759
128Widely spaced teeth (HP:0000687)1.82171311
129Increased neuronal autofluorescent lipopigment (HP:0002074)1.81966293
130Abnormal social behavior (HP:0012433)1.81936318
131Impaired social interactions (HP:0000735)1.81936318
132Postural tremor (HP:0002174)1.81470151
133Alveolar cell carcinoma (HP:0006519)1.81359623
134EEG with generalized epileptiform discharges (HP:0011198)1.81284250
135Peripheral hypomyelination (HP:0007182)1.81062772
136Rigidity (HP:0002063)1.81055404
137Overgrowth (HP:0001548)1.80374915
138Large earlobe (HP:0009748)1.78490280
139Inability to walk (HP:0002540)1.78369719
140Psychosis (HP:0000709)1.78087698
141Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.77912242
142Clonus (HP:0002169)1.77828925
143Foot dorsiflexor weakness (HP:0009027)1.77814262
144Blue irides (HP:0000635)1.77625248
145Impaired vibratory sensation (HP:0002495)1.76926270
146Hemiparesis (HP:0001269)1.76642914
147Menstrual irregularities (HP:0000858)1.76325831
148Gait imbalance (HP:0002141)1.75838357
149Disproportionate short-trunk short stature (HP:0003521)1.75318305
150Abnormal neuron morphology (HP:0012757)1.74861323
151Abnormality of the motor neurons (HP:0002450)1.74861323
152Spastic tetraplegia (HP:0002510)1.74361755
153Hand muscle atrophy (HP:0009130)1.74329671
154Facial diplegia (HP:0001349)1.73601999
155Pelvic girdle muscle weakness (HP:0003749)1.71666207
156Keratoconjunctivitis sicca (HP:0001097)1.71040169
157Recurrent skin infections (HP:0001581)1.70267438
158Gingivitis (HP:0000230)1.68364247
159Peritonitis (HP:0002586)1.67589544
160Hypsarrhythmia (HP:0002521)1.66982717
161Fetal akinesia sequence (HP:0001989)1.66729188
162Frequent falls (HP:0002359)1.64887499

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.56890457
2ERBB33.13713018
3MAP3K92.91688769
4RIPK42.70060331
5NTRK12.60642816
6MAP3K122.41487231
7EPHA32.41438021
8MAP3K42.40447602
9TRIM282.39194835
10MINK12.34627748
11SIK32.30829868
12CASK2.30638649
13KSR22.18412792
14MAP2K72.17027680
15PRKD32.09742616
16MARK11.91436666
17STK391.87603066
18AKT31.85629727
19MAP3K141.83835823
20CAMKK21.80082036
21PDK31.72779395
22PDK41.72779395
23MAP2K41.70585483
24DAPK21.70193580
25MAP3K61.68680636
26PAK61.68499442
27EPHA41.67036847
28MAP3K21.66014876
29ARAF1.57732680
30WNK11.56464940
31WNK41.53895837
32CAMKK11.52416818
33PIK3CG1.45075004
34LMTK21.43861481
35GRK51.36673609
36IRAK21.34914869
37PTK2B1.32878002
38CDK51.30453718
39SGK2231.27066793
40SGK4941.27066793
41RET1.27013251
42STK241.26492195
43EIF2AK31.25046814
44PRKCH1.23759010
45TESK11.23402058
46PLK21.22034610
47PDK21.21487444
48YES11.21162111
49OXSR11.19473588
50IRAK11.18574121
51LIMK11.16890079
52MAP3K131.13589607
53BLK1.09518670
54TGFBR21.09438879
55MAPK131.09368893
56SCYL21.08695100
57PHKG11.08456755
58PHKG21.08456755
59DYRK31.08169585
60BRD41.07974771
61CSK1.07615546
62MAP3K51.06958472
63FES0.99528034
64TYK20.99339127
65MAP3K10.98376063
66PRPF4B0.98181704
67NTRK20.97096670
68CSNK1A1L0.95547010
69PDK10.91935817
70ZAP700.91762543
71CSNK1G30.90513508
72GRK70.89522180
73SGK30.89342523
74SGK20.87896030
75IRAK40.87230615
76IKBKE0.85337902
77PDPK10.83927533
78UHMK10.81610667
79PRKCG0.79315961
80CAMK2A0.79003281
81MAPKAPK50.78927576
82FRK0.78054964
83NEK90.76623045
84BMPR20.75841587
85DAPK10.74139530
86TEC0.73631614
87PAK30.72710180
88PRKCE0.72319715
89STK380.71691510
90EGFR0.70236598
91HCK0.69216695
92FGR0.68188773
93JAK10.67753731
94CSNK1G10.67691694
95RPS6KA40.65536967
96CDK190.65305011
97STK110.64878000
98DYRK1A0.64855415
99EPHB10.64482581
100MAP2K10.62854560
101CDK60.61493465
102CAMK2B0.61266120
103PNCK0.60872338
104KSR10.60061494
105CDK140.58380593
106RPS6KA20.58156986
107TBK10.57477273
108FGFR20.57000346
109TYRO30.54110395
110MATK0.53187111
111SGK10.52673390
112BCR0.52403307
113CAMK1G0.49605766
114CSNK1G20.49578284
115DYRK1B0.49472287
116PINK10.49413303
117FYN0.49334531
118CDK180.47905887
119RAF10.46993855
120TNIK0.46499542
121TAOK30.45749511
122ADRBK10.45718471
123CDK150.45621006
124DMPK0.44830861
125CAMK2G0.44278246
126PDGFRB0.43763929
127CAMK2D0.43626135
128LCK0.43616110
129MARK20.43587887
130ROCK20.42323781
131MAP4K20.41727373
132SYK0.41501422
133CAMK40.40635614
134PRKCZ0.39913240
135TRPM70.37702714
136INSRR0.37497719
137JAK20.37265683
138CSF1R0.37175110
139FGFR30.36719877
140FER0.36105528
141TAOK10.35134426
142SIK20.33784518
143PRKCQ0.33536984

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047212.91880157
2Nicotine addiction_Homo sapiens_hsa050332.02631968
3Long-term potentiation_Homo sapiens_hsa047202.00939427
4Olfactory transduction_Homo sapiens_hsa047401.99232926
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.99053236
6Circadian entrainment_Homo sapiens_hsa047131.94085401
7Collecting duct acid secretion_Homo sapiens_hsa049661.89484261
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.88970877
9Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.86873540
10Morphine addiction_Homo sapiens_hsa050321.86699819
11GABAergic synapse_Homo sapiens_hsa047271.83507767
12Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.81411466
13Amphetamine addiction_Homo sapiens_hsa050311.76072721
14Dopaminergic synapse_Homo sapiens_hsa047281.75729552
15Glutamatergic synapse_Homo sapiens_hsa047241.67366591
16Insulin secretion_Homo sapiens_hsa049111.66425224
17Renin secretion_Homo sapiens_hsa049241.62735445
18Cholinergic synapse_Homo sapiens_hsa047251.58877969
19Salivary secretion_Homo sapiens_hsa049701.54623939
20Legionellosis_Homo sapiens_hsa051341.53963520
21Gastric acid secretion_Homo sapiens_hsa049711.51762836
22NOD-like receptor signaling pathway_Homo sapiens_hsa046211.39135896
23Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.38194165
24Vibrio cholerae infection_Homo sapiens_hsa051101.37246335
25Serotonergic synapse_Homo sapiens_hsa047261.33138025
26Taste transduction_Homo sapiens_hsa047421.29866303
27Dorso-ventral axis formation_Homo sapiens_hsa043201.29586235
28Shigellosis_Homo sapiens_hsa051311.27732992
29Circadian rhythm_Homo sapiens_hsa047101.26891780
30Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.26504433
31Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.26212152
32Aldosterone synthesis and secretion_Homo sapiens_hsa049251.26176481
33Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26101739
34Type II diabetes mellitus_Homo sapiens_hsa049301.25072597
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.25003933
36Regulation of autophagy_Homo sapiens_hsa041401.24569406
37Long-term depression_Homo sapiens_hsa047301.24494466
38Oxytocin signaling pathway_Homo sapiens_hsa049211.23627777
39Cocaine addiction_Homo sapiens_hsa050301.22322231
40Calcium signaling pathway_Homo sapiens_hsa040201.15664935
41GnRH signaling pathway_Homo sapiens_hsa049121.13536024
42Rheumatoid arthritis_Homo sapiens_hsa053231.11633234
43* Phosphatidylinositol signaling system_Homo sapiens_hsa040701.07331733
44Phagosome_Homo sapiens_hsa041451.07005205
45Hepatitis B_Homo sapiens_hsa051611.06233033
46TNF signaling pathway_Homo sapiens_hsa046681.04621041
47AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.03928153
48Toxoplasmosis_Homo sapiens_hsa051451.01901165
49Estrogen signaling pathway_Homo sapiens_hsa049151.01107076
50cAMP signaling pathway_Homo sapiens_hsa040240.97696223
51Endometrial cancer_Homo sapiens_hsa052130.95298832
52RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.94905435
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.94745971
54Endocytosis_Homo sapiens_hsa041440.94018566
55Gap junction_Homo sapiens_hsa045400.93232712
56Lysosome_Homo sapiens_hsa041420.92838448
57Glioma_Homo sapiens_hsa052140.91982113
58Pancreatic cancer_Homo sapiens_hsa052120.91964057
59Colorectal cancer_Homo sapiens_hsa052100.91721525
60Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.91545253
61Non-small cell lung cancer_Homo sapiens_hsa052230.89019898
62Vascular smooth muscle contraction_Homo sapiens_hsa042700.87804966
63Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.87750397
64Salmonella infection_Homo sapiens_hsa051320.87102248
65cGMP-PKG signaling pathway_Homo sapiens_hsa040220.86591409
66Neurotrophin signaling pathway_Homo sapiens_hsa047220.86286612
67Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.85091120
68ErbB signaling pathway_Homo sapiens_hsa040120.85078350
69Protein export_Homo sapiens_hsa030600.84742131
70Pancreatic secretion_Homo sapiens_hsa049720.84569682
71SNARE interactions in vesicular transport_Homo sapiens_hsa041300.84241105
72Axon guidance_Homo sapiens_hsa043600.82148067
73Carbohydrate digestion and absorption_Homo sapiens_hsa049730.81266841
74Sphingolipid signaling pathway_Homo sapiens_hsa040710.78295427
75Measles_Homo sapiens_hsa051620.78224702
76Chemokine signaling pathway_Homo sapiens_hsa040620.78123627
77Type I diabetes mellitus_Homo sapiens_hsa049400.77445053
78Phospholipase D signaling pathway_Homo sapiens_hsa040720.76874090
79Jak-STAT signaling pathway_Homo sapiens_hsa046300.76816106
80VEGF signaling pathway_Homo sapiens_hsa043700.76669084
81Tuberculosis_Homo sapiens_hsa051520.74785490
82Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.74590764
83Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.74296930
84Leukocyte transendothelial migration_Homo sapiens_hsa046700.73020048
85Influenza A_Homo sapiens_hsa051640.72630251
86MAPK signaling pathway_Homo sapiens_hsa040100.71919858
87Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.71194931
88FoxO signaling pathway_Homo sapiens_hsa040680.69369669
89Malaria_Homo sapiens_hsa051440.69245963
90Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.68868691
91Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.68568037
92Regulation of actin cytoskeleton_Homo sapiens_hsa048100.68025567
93Glucagon signaling pathway_Homo sapiens_hsa049220.67697902
94Glycosaminoglycan degradation_Homo sapiens_hsa005310.66742140
95Chronic myeloid leukemia_Homo sapiens_hsa052200.65264120
96Osteoclast differentiation_Homo sapiens_hsa043800.65083051
97Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.64781178
98Acute myeloid leukemia_Homo sapiens_hsa052210.64334275
99Pertussis_Homo sapiens_hsa051330.64193108
100Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.63715984
101Hepatitis C_Homo sapiens_hsa051600.63317923
102Prion diseases_Homo sapiens_hsa050200.63144008
103Renal cell carcinoma_Homo sapiens_hsa052110.62616816
104Thyroid hormone synthesis_Homo sapiens_hsa049180.62433965
105Ras signaling pathway_Homo sapiens_hsa040140.60852718
106Cardiac muscle contraction_Homo sapiens_hsa042600.58787936
107HIF-1 signaling pathway_Homo sapiens_hsa040660.56104204
108Choline metabolism in cancer_Homo sapiens_hsa052310.55581838
109Melanogenesis_Homo sapiens_hsa049160.55050242
110Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.54533379
111Dilated cardiomyopathy_Homo sapiens_hsa054140.54298921
112Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.52913927
113Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.49792137
114African trypanosomiasis_Homo sapiens_hsa051430.49567472
115Rap1 signaling pathway_Homo sapiens_hsa040150.49565590
116* Inositol phosphate metabolism_Homo sapiens_hsa005620.49381729
117Insulin signaling pathway_Homo sapiens_hsa049100.48914659
118Platelet activation_Homo sapiens_hsa046110.48764926
119Prolactin signaling pathway_Homo sapiens_hsa049170.47566244
120Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.46450749
121Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45827281
122mTOR signaling pathway_Homo sapiens_hsa041500.45540546
123B cell receptor signaling pathway_Homo sapiens_hsa046620.44614211
124Oocyte meiosis_Homo sapiens_hsa041140.44452589
125Ether lipid metabolism_Homo sapiens_hsa005650.44394091
126Toll-like receptor signaling pathway_Homo sapiens_hsa046200.43977078
127Amoebiasis_Homo sapiens_hsa051460.43735158
128Alzheimers disease_Homo sapiens_hsa050100.42115630
129Leishmaniasis_Homo sapiens_hsa051400.41033045
130T cell receptor signaling pathway_Homo sapiens_hsa046600.39645019
131Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.38236189

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