

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 7.18985637 |
| 2 | detection of molecule of bacterial origin (GO:0032490) | 5.99269688 |
| 3 | positive regulation of B cell differentiation (GO:0045579) | 5.41753926 |
| 4 | regulation of gamma-delta T cell activation (GO:0046643) | 5.38916623 |
| 5 | positive regulation by symbiont of host defense response (GO:0052509) | 5.22350830 |
| 6 | modulation by symbiont of host defense response (GO:0052031) | 5.22350830 |
| 7 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.22350830 |
| 8 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.22350830 |
| 9 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.22350830 |
| 10 | modulation by symbiont of host immune response (GO:0052553) | 5.22350830 |
| 11 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.17515256 |
| 12 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 5.02852785 |
| 13 | response to peptidoglycan (GO:0032494) | 4.98041529 |
| 14 | neutrophil activation involved in immune response (GO:0002283) | 4.76876760 |
| 15 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.75766718 |
| 16 | macrophage activation involved in immune response (GO:0002281) | 4.55521597 |
| 17 | T-helper 1 type immune response (GO:0042088) | 4.44624969 |
| 18 | microglial cell activation (GO:0001774) | 4.40448076 |
| 19 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.40249305 |
| 20 | response to host immune response (GO:0052572) | 4.39812921 |
| 21 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.39812921 |
| 22 | negative regulation of interleukin-17 production (GO:0032700) | 4.35562163 |
| 23 | detection of external biotic stimulus (GO:0098581) | 4.34133265 |
| 24 | B cell receptor signaling pathway (GO:0050853) | 4.29131583 |
| 25 | negative regulation of interleukin-12 production (GO:0032695) | 4.15882153 |
| 26 | detection of other organism (GO:0098543) | 4.13502442 |
| 27 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 4.02951218 |
| 28 | response to host (GO:0075136) | 4.02951218 |
| 29 | response to host defenses (GO:0052200) | 4.02951218 |
| 30 | positive regulation of type 2 immune response (GO:0002830) | 4.01949411 |
| 31 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.92847936 |
| 32 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.92847936 |
| 33 | macrophage activation (GO:0042116) | 3.92831086 |
| 34 | positive regulation of interferon-beta production (GO:0032728) | 3.92149077 |
| 35 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.91682166 |
| 36 | cellular extravasation (GO:0045123) | 3.81096665 |
| 37 | regulation of B cell differentiation (GO:0045577) | 3.79702578 |
| 38 | regulation of regulatory T cell differentiation (GO:0045589) | 3.79459922 |
| 39 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.79208760 |
| 40 | positive regulation of interferon-alpha production (GO:0032727) | 3.77341793 |
| 41 | detection of biotic stimulus (GO:0009595) | 3.75640332 |
| 42 | regulation of interferon-alpha production (GO:0032647) | 3.71017495 |
| 43 | neutrophil activation (GO:0042119) | 3.66410171 |
| 44 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.63224789 |
| 45 | response to muramyl dipeptide (GO:0032495) | 3.62885449 |
| 46 | histone H3-K36 demethylation (GO:0070544) | 3.61452679 |
| 47 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.58838718 |
| 48 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.57274853 |
| 49 | histamine secretion (GO:0001821) | 3.54658411 |
| 50 | negative regulation of T cell mediated immunity (GO:0002710) | 3.51454881 |
| 51 | detection of bacterium (GO:0016045) | 3.49873839 |
| 52 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.49762445 |
| 53 | leukotriene biosynthetic process (GO:0019370) | 3.47735879 |
| 54 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.45934685 |
| 55 | negative T cell selection (GO:0043383) | 3.45456729 |
| 56 | immunoglobulin mediated immune response (GO:0016064) | 3.44282477 |
| 57 | myeloid cell activation involved in immune response (GO:0002275) | 3.43852331 |
| 58 | positive regulation of macrophage cytokine production (GO:0060907) | 3.43718758 |
| 59 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.43368153 |
| 60 | positive regulation of granulocyte differentiation (GO:0030854) | 3.42675533 |
| 61 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.42437742 |
| 62 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.41711236 |
| 63 | regulation of memory T cell differentiation (GO:0043380) | 3.40997331 |
| 64 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.39645257 |
| 65 | negative regulation of cell killing (GO:0031342) | 3.39645257 |
| 66 | regulation of interleukin-17 production (GO:0032660) | 3.32848044 |
| 67 | granulocyte activation (GO:0036230) | 3.30629331 |
| 68 | nucleoside diphosphate catabolic process (GO:0009134) | 3.28896361 |
| 69 | negative thymic T cell selection (GO:0045060) | 3.28162117 |
| 70 | positive regulation of antigen processing and presentation (GO:0002579) | 3.28094672 |
| 71 | regulation of germinal center formation (GO:0002634) | 3.21044901 |
| 72 | regulation of interferon-beta production (GO:0032648) | 3.20918362 |
| 73 | B cell mediated immunity (GO:0019724) | 3.20871099 |
| 74 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.18101171 |
| 75 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.17319261 |
| 76 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.16279031 |
| 77 | interferon-gamma secretion (GO:0072643) | 3.16228014 |
| 78 | positive T cell selection (GO:0043368) | 3.15754864 |
| 79 | positive thymic T cell selection (GO:0045059) | 3.15189750 |
| 80 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.11182003 |
| 81 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.10855157 |
| 82 | regulation of B cell mediated immunity (GO:0002712) | 3.07703302 |
| 83 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.06056450 |
| 84 | regulation of macrophage cytokine production (GO:0010935) | 3.05093870 |
| 85 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.04380951 |
| 86 | neutrophil mediated immunity (GO:0002446) | 2.97056309 |
| 87 | regulation of interleukin-12 production (GO:0032655) | 2.96626721 |
| 88 | positive regulation of B cell activation (GO:0050871) | 2.95487025 |
| 89 | leukotriene metabolic process (GO:0006691) | 2.95259731 |
| 90 | positive regulation of interleukin-12 production (GO:0032735) | 2.94014234 |
| 91 | histone H3-K4 trimethylation (GO:0080182) | 2.93832070 |
| 92 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.93445397 |
| 93 | interferon-gamma production (GO:0032609) | 2.93422268 |
| 94 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.93381374 |
| 95 | response to interferon-alpha (GO:0035455) | 2.93106089 |
| 96 | negative regulation of adaptive immune response (GO:0002820) | 2.89454473 |
| 97 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.88667028 |
| 98 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.84228886 |
| 99 | positive regulation of isotype switching (GO:0045830) | 2.83135024 |
| 100 | histamine transport (GO:0051608) | 2.81740341 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.97587532 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.91899836 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.82646798 |
| 4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.41310780 |
| 5 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.14158303 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.01065998 |
| 7 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.93082354 |
| 8 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.91737410 |
| 9 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.88070246 |
| 10 | GATA1_22025678_ChIP-Seq_K562_Human | 2.78597470 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.78329509 |
| 12 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.74686555 |
| 13 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.71220182 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.59382873 |
| 15 | MYB_26560356_Chip-Seq_TH2_Human | 2.44730855 |
| 16 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.43213185 |
| 17 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.40576717 |
| 18 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.31887449 |
| 19 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.06896412 |
| 20 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.04068117 |
| 21 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.03749755 |
| 22 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.98579769 |
| 23 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.94865990 |
| 24 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.93715593 |
| 25 | SPI1_23127762_ChIP-Seq_K562_Human | 1.91736888 |
| 26 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.90989197 |
| 27 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.84260328 |
| 28 | GATA3_26560356_Chip-Seq_TH2_Human | 1.78694939 |
| 29 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.76483207 |
| 30 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.67405655 |
| 31 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.67352249 |
| 32 | MYB_26560356_Chip-Seq_TH1_Human | 1.66629022 |
| 33 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.64949003 |
| 34 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.55350311 |
| 35 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.54138468 |
| 36 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.51083977 |
| 37 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.49596917 |
| 38 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.45281748 |
| 39 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.44764451 |
| 40 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.43076206 |
| 41 | TP53_16413492_ChIP-PET_HCT116_Human | 1.38309197 |
| 42 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.37572959 |
| 43 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.35159836 |
| 44 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.31149704 |
| 45 | MAF_26560356_Chip-Seq_TH1_Human | 1.29050677 |
| 46 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.28390220 |
| 47 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.28390220 |
| 48 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.28258318 |
| 49 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.27919697 |
| 50 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.26055687 |
| 51 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.25457335 |
| 52 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.24838430 |
| 53 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.22101932 |
| 54 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.21703046 |
| 55 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.21046291 |
| 56 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.19983232 |
| 57 | GATA1_19941826_ChIP-Seq_K562_Human | 1.19005277 |
| 58 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.18413075 |
| 59 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.18058566 |
| 60 | VDR_22108803_ChIP-Seq_LS180_Human | 1.14602947 |
| 61 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.14560879 |
| 62 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.14226625 |
| 63 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.13433728 |
| 64 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.11180198 |
| 65 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.08931500 |
| 66 | UTX_26944678_Chip-Seq_JUKART_Human | 1.08504260 |
| 67 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.07252978 |
| 68 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.06778794 |
| 69 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.05253565 |
| 70 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.01520063 |
| 71 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.01119500 |
| 72 | GATA2_19941826_ChIP-Seq_K562_Human | 1.00932540 |
| 73 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.00432736 |
| 74 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.00295860 |
| 75 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.99729769 |
| 76 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.99566643 |
| 77 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.98916650 |
| 78 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.97100825 |
| 79 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.96282024 |
| 80 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.96126398 |
| 81 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.95080254 |
| 82 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.94291820 |
| 83 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.93527880 |
| 84 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.92071869 |
| 85 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.90121536 |
| 86 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.89181862 |
| 87 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.88857606 |
| 88 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.88277655 |
| 89 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.88277655 |
| 90 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.87958220 |
| 91 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.87741632 |
| 92 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.87370439 |
| 93 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.86351248 |
| 94 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.86157161 |
| 95 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.85346195 |
| 96 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.85033252 |
| 97 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.83526723 |
| 98 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82446629 |
| 99 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.82328859 |
| 100 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.81772144 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003303_peritoneal_inflammation | 4.45986651 |
| 2 | MP0001835_abnormal_antigen_presentation | 4.44911014 |
| 3 | MP0003724_increased_susceptibility_to | 4.34923795 |
| 4 | MP0001800_abnormal_humoral_immune | 3.00064172 |
| 5 | MP0003436_decreased_susceptibility_to | 2.73775884 |
| 6 | MP0000685_abnormal_immune_system | 2.71264722 |
| 7 | MP0000569_abnormal_digit_pigmentation | 2.67016734 |
| 8 | MP0003656_abnormal_erythrocyte_physiolo | 2.59764760 |
| 9 | MP0002419_abnormal_innate_immunity | 2.55472732 |
| 10 | MP0002452_abnormal_antigen_presenting | 2.48119883 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.46081411 |
| 12 | MP0002723_abnormal_immune_serum | 2.36335354 |
| 13 | MP0009785_altered_susceptibility_to | 2.33763455 |
| 14 | MP0001853_heart_inflammation | 2.28495899 |
| 15 | MP0003172_abnormal_lysosome_physiology | 2.26500985 |
| 16 | MP0005671_abnormal_response_to | 2.26367504 |
| 17 | MP0002148_abnormal_hypersensitivity_rea | 2.25596681 |
| 18 | MP0005387_immune_system_phenotype | 2.24509171 |
| 19 | MP0001790_abnormal_immune_system | 2.24509171 |
| 20 | MP0006082_CNS_inflammation | 2.19230855 |
| 21 | MP0002420_abnormal_adaptive_immunity | 2.15971795 |
| 22 | MP0001819_abnormal_immune_cell | 2.14453661 |
| 23 | MP0005025_abnormal_response_to | 2.10560528 |
| 24 | MP0002166_altered_tumor_susceptibility | 2.04915640 |
| 25 | MP0008260_abnormal_autophagy | 1.99764892 |
| 26 | MP0009764_decreased_sensitivity_to | 1.96003411 |
| 27 | MP0000015_abnormal_ear_pigmentation | 1.94864468 |
| 28 | MP0002396_abnormal_hematopoietic_system | 1.93893641 |
| 29 | MP0009278_abnormal_bone_marrow | 1.80037981 |
| 30 | MP0003183_abnormal_peptide_metabolism | 1.78954865 |
| 31 | MP0002398_abnormal_bone_marrow | 1.77629470 |
| 32 | MP0005409_darkened_coat_color | 1.76029982 |
| 33 | MP0004808_abnormal_hematopoietic_stem | 1.72282154 |
| 34 | MP0000716_abnormal_immune_system | 1.67956760 |
| 35 | MP0001545_abnormal_hematopoietic_system | 1.65154041 |
| 36 | MP0005397_hematopoietic_system_phenotyp | 1.65154041 |
| 37 | MP0005464_abnormal_platelet_physiology | 1.64223095 |
| 38 | MP0003763_abnormal_thymus_physiology | 1.64040136 |
| 39 | MP0005310_abnormal_salivary_gland | 1.61124774 |
| 40 | MP0002405_respiratory_system_inflammati | 1.59885294 |
| 41 | MP0004883_abnormal_blood_vessel | 1.58113503 |
| 42 | MP0003300_gastrointestinal_ulcer | 1.57883769 |
| 43 | MP0003646_muscle_fatigue | 1.53865920 |
| 44 | MP0000689_abnormal_spleen_morphology | 1.51822569 |
| 45 | MP0005174_abnormal_tail_pigmentation | 1.42592785 |
| 46 | MP0001533_abnormal_skeleton_physiology | 1.41133559 |
| 47 | MP0010155_abnormal_intestine_physiology | 1.40712597 |
| 48 | MP0002722_abnormal_immune_system | 1.38502897 |
| 49 | MP0002006_tumorigenesis | 1.36406462 |
| 50 | MP0002009_preneoplasia | 1.35424997 |
| 51 | MP0003806_abnormal_nucleotide_metabolis | 1.35314123 |
| 52 | MP0005164_abnormal_response_to | 1.33154789 |
| 53 | MP0001845_abnormal_inflammatory_respons | 1.30440089 |
| 54 | MP0004947_skin_inflammation | 1.29770830 |
| 55 | MP0002429_abnormal_blood_cell | 1.29101171 |
| 56 | MP0002332_abnormal_exercise_endurance | 1.26659047 |
| 57 | MP0003191_abnormal_cellular_cholesterol | 1.22305023 |
| 58 | MP0004381_abnormal_hair_follicle | 1.18134279 |
| 59 | MP0002132_abnormal_respiratory_system | 1.14733909 |
| 60 | MP0008469_abnormal_protein_level | 1.14340402 |
| 61 | MP0000371_diluted_coat_color | 1.13566338 |
| 62 | MP0008995_early_reproductive_senescence | 1.12357508 |
| 63 | MP0003045_fibrosis | 1.10695190 |
| 64 | MP0003828_pulmonary_edema | 1.07131624 |
| 65 | MP0000703_abnormal_thymus_morphology | 1.06260468 |
| 66 | MP0008057_abnormal_DNA_replication | 1.05520101 |
| 67 | MP0009765_abnormal_xenobiotic_induced | 1.05478758 |
| 68 | MP0002095_abnormal_skin_pigmentation | 1.01994721 |
| 69 | MP0008058_abnormal_DNA_repair | 1.01579970 |
| 70 | MP0003690_abnormal_glial_cell | 0.98972595 |
| 71 | MP0004130_abnormal_muscle_cell | 0.96296558 |
| 72 | MP0005075_abnormal_melanosome_morpholog | 0.93961373 |
| 73 | MP0000372_irregular_coat_pigmentation | 0.92625035 |
| 74 | MP0003075_altered_response_to | 0.88375387 |
| 75 | MP0002277_abnormal_respiratory_mucosa | 0.87375999 |
| 76 | MP0009115_abnormal_fat_cell | 0.86234229 |
| 77 | MP0001663_abnormal_digestive_system | 0.86157745 |
| 78 | MP0003866_abnormal_defecation | 0.84484858 |
| 79 | MP0008961_abnormal_basal_metabolism | 0.84195906 |
| 80 | MP0000858_altered_metastatic_potential | 0.83261655 |
| 81 | MP0005376_homeostasis/metabolism_phenot | 0.79187078 |
| 82 | MP0002998_abnormal_bone_remodeling | 0.78413884 |
| 83 | MP0009763_increased_sensitivity_to | 0.77402936 |
| 84 | MP0008004_abnormal_stomach_pH | 0.76233203 |
| 85 | MP0004043_abnormal_pH_regulation | 0.73155171 |
| 86 | MP0000249_abnormal_blood_vessel | 0.71465269 |
| 87 | MP0005408_hypopigmentation | 0.69436300 |
| 88 | MP0004484_altered_response_of | 0.69352974 |
| 89 | MP0005171_absent_coat_pigmentation | 0.69201723 |
| 90 | MP0002019_abnormal_tumor_incidence | 0.68223854 |
| 91 | MP0004147_increased_porphyrin_level | 0.67451630 |
| 92 | MP0001851_eye_inflammation | 0.64849782 |
| 93 | MP0005166_decreased_susceptibility_to | 0.64725010 |
| 94 | MP0005646_abnormal_pituitary_gland | 0.64590021 |
| 95 | MP0005451_abnormal_body_composition | 0.62144599 |
| 96 | MP0005334_abnormal_fat_pad | 0.60598865 |
| 97 | MP0002138_abnormal_hepatobiliary_system | 0.56235166 |
| 98 | MP0000465_gastrointestinal_hemorrhage | 0.55965056 |
| 99 | MP0005266_abnormal_metabolism | 0.55691666 |
| 100 | MP0005535_abnormal_body_temperature | 0.55555670 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Recurrent bacterial skin infections (HP:0005406) | 5.73243176 |
| 2 | Panhypogammaglobulinemia (HP:0003139) | 5.62772326 |
| 3 | Recurrent abscess formation (HP:0002722) | 4.84576462 |
| 4 | Optic neuritis (HP:0100653) | 4.73862731 |
| 5 | Retrobulbar optic neuritis (HP:0100654) | 4.73862731 |
| 6 | Chronic otitis media (HP:0000389) | 4.61099470 |
| 7 | Orchitis (HP:0100796) | 4.47222961 |
| 8 | Myositis (HP:0100614) | 4.36658549 |
| 9 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 4.30418200 |
| 10 | Gastrointestinal infarctions (HP:0005244) | 4.22822811 |
| 11 | Recurrent cutaneous fungal infections (HP:0011370) | 4.18912902 |
| 12 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.18912902 |
| 13 | Recurrent skin infections (HP:0001581) | 4.15279898 |
| 14 | Agammaglobulinemia (HP:0004432) | 4.12424662 |
| 15 | Encephalitis (HP:0002383) | 4.04767232 |
| 16 | Increased cerebral lipofuscin (HP:0011813) | 3.93003472 |
| 17 | Viral hepatitis (HP:0006562) | 3.92234401 |
| 18 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.78609362 |
| 19 | Abnormality of the prostate (HP:0008775) | 3.78217918 |
| 20 | Recurrent viral infections (HP:0004429) | 3.76731916 |
| 21 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.75719885 |
| 22 | Meningitis (HP:0001287) | 3.70138962 |
| 23 | Arterial thrombosis (HP:0004420) | 3.61839937 |
| 24 | Recurrent fungal infections (HP:0002841) | 3.49316229 |
| 25 | Chest pain (HP:0100749) | 3.41158762 |
| 26 | Keratoconjunctivitis sicca (HP:0001097) | 3.34233151 |
| 27 | Gingival bleeding (HP:0000225) | 3.27948568 |
| 28 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 3.23995924 |
| 29 | Hemoptysis (HP:0002105) | 3.20060445 |
| 30 | Pulmonary infiltrates (HP:0002113) | 3.19095051 |
| 31 | Keratoconjunctivitis (HP:0001096) | 3.13751834 |
| 32 | Eczematoid dermatitis (HP:0000976) | 3.04647289 |
| 33 | Vasculitis (HP:0002633) | 3.03883481 |
| 34 | Gangrene (HP:0100758) | 2.96806228 |
| 35 | T lymphocytopenia (HP:0005403) | 2.93233407 |
| 36 | Abnormality of T cell number (HP:0011839) | 2.91452880 |
| 37 | Peritonitis (HP:0002586) | 2.71139188 |
| 38 | Stomatitis (HP:0010280) | 2.69867214 |
| 39 | Abnormality of the right ventricle (HP:0001707) | 2.68623872 |
| 40 | Abnormality of glycolipid metabolism (HP:0010969) | 2.63543403 |
| 41 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.63543403 |
| 42 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.63543403 |
| 43 | Amaurosis fugax (HP:0100576) | 2.61264143 |
| 44 | Epistaxis (HP:0000421) | 2.59084555 |
| 45 | Pulmonary embolism (HP:0002204) | 2.56633415 |
| 46 | Cellulitis (HP:0100658) | 2.52374264 |
| 47 | Tinnitus (HP:0000360) | 2.51296657 |
| 48 | Colitis (HP:0002583) | 2.48809407 |
| 49 | Abnormality of T cells (HP:0002843) | 2.45685102 |
| 50 | Mediastinal lymphadenopathy (HP:0100721) | 2.44017210 |
| 51 | Chronic obstructive pulmonary disease (HP:0006510) | 2.42544052 |
| 52 | Obstructive lung disease (HP:0006536) | 2.42544052 |
| 53 | Thrombophlebitis (HP:0004418) | 2.37545776 |
| 54 | Urethral obstruction (HP:0000796) | 2.36056852 |
| 55 | Abnormality of T cell physiology (HP:0011840) | 2.34515456 |
| 56 | Anorexia (HP:0002039) | 2.32221890 |
| 57 | Abnormality of male internal genitalia (HP:0000022) | 2.29752473 |
| 58 | Gingivitis (HP:0000230) | 2.27994690 |
| 59 | Clumsiness (HP:0002312) | 2.27248131 |
| 60 | Abnormality of the fingertips (HP:0001211) | 2.27084615 |
| 61 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.26253524 |
| 62 | Genetic anticipation (HP:0003743) | 2.24624842 |
| 63 | Abolished electroretinogram (ERG) (HP:0000550) | 2.24365418 |
| 64 | Acute hepatic failure (HP:0006554) | 2.21720727 |
| 65 | Spontaneous hematomas (HP:0007420) | 2.19936613 |
| 66 | Inflammation of the large intestine (HP:0002037) | 2.19790008 |
| 67 | Abnormality of the pleura (HP:0002103) | 2.19416237 |
| 68 | Vertigo (HP:0002321) | 2.19381907 |
| 69 | Osteomyelitis (HP:0002754) | 2.12080210 |
| 70 | Prolonged bleeding time (HP:0003010) | 2.09285941 |
| 71 | Tubulointerstitial nephritis (HP:0001970) | 2.09012307 |
| 72 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.08161680 |
| 73 | Autoimmune thrombocytopenia (HP:0001973) | 2.05890817 |
| 74 | Diplopia (HP:0000651) | 2.04961759 |
| 75 | Abnormality of binocular vision (HP:0011514) | 2.04961759 |
| 76 | Acute myeloid leukemia (HP:0004808) | 2.04441924 |
| 77 | Urticaria (HP:0001025) | 2.02516693 |
| 78 | Xerostomia (HP:0000217) | 2.00862561 |
| 79 | Interstitial pulmonary disease (HP:0006530) | 2.00787107 |
| 80 | Spontaneous abortion (HP:0005268) | 1.99659330 |
| 81 | Abnormality of macrophages (HP:0004311) | 1.99407345 |
| 82 | Recurrent bronchitis (HP:0002837) | 1.98902564 |
| 83 | Abnormality of the peritoneum (HP:0002585) | 1.98309974 |
| 84 | Leukocytosis (HP:0001974) | 1.97708528 |
| 85 | Ureteral obstruction (HP:0006000) | 1.97687538 |
| 86 | Skin rash (HP:0000988) | 1.96573606 |
| 87 | Thrombocytosis (HP:0001894) | 1.95668579 |
| 88 | Postural instability (HP:0002172) | 1.95126111 |
| 89 | Gastrointestinal inflammation (HP:0004386) | 1.94712548 |
| 90 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.89252836 |
| 91 | Gaze-evoked nystagmus (HP:0000640) | 1.86055820 |
| 92 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.84837974 |
| 93 | Poikilocytosis (HP:0004447) | 1.84726878 |
| 94 | Thickened calvaria (HP:0002684) | 1.84535951 |
| 95 | Polyneuropathy (HP:0001271) | 1.84147914 |
| 96 | Glomerulopathy (HP:0100820) | 1.83302385 |
| 97 | Hepatitis (HP:0012115) | 1.79280288 |
| 98 | Keratitis (HP:0000491) | 1.78756035 |
| 99 | Amyloidosis (HP:0011034) | 1.76720177 |
| 100 | Portal hypertension (HP:0001409) | 1.74797576 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.09066705 |
| 2 | TEC | 3.35008604 |
| 3 | BCKDK | 3.06356114 |
| 4 | ITK | 2.81067161 |
| 5 | BLK | 2.72382535 |
| 6 | IRAK4 | 2.61671863 |
| 7 | TAOK3 | 2.58905370 |
| 8 | MAP4K1 | 2.57411978 |
| 9 | BTK | 2.23317972 |
| 10 | SYK | 2.19403226 |
| 11 | TXK | 2.14764505 |
| 12 | IKBKE | 2.01562382 |
| 13 | IRAK1 | 1.96074203 |
| 14 | CAMK1D | 1.95002980 |
| 15 | BRD4 | 1.90787568 |
| 16 | FES | 1.87342965 |
| 17 | MAPKAPK3 | 1.81886859 |
| 18 | BMPR2 | 1.80385069 |
| 19 | MAP2K3 | 1.74644187 |
| 20 | FRK | 1.71665045 |
| 21 | CSK | 1.60415972 |
| 22 | WNK1 | 1.58432983 |
| 23 | PIK3CG | 1.57858644 |
| 24 | TBK1 | 1.56971083 |
| 25 | TYK2 | 1.53438132 |
| 26 | IRAK2 | 1.51701075 |
| 27 | JAK3 | 1.38849833 |
| 28 | ZAP70 | 1.37201131 |
| 29 | KIT | 1.35874683 |
| 30 | TNK2 | 1.35508230 |
| 31 | LYN | 1.33839218 |
| 32 | MAP3K14 | 1.33370739 |
| 33 | AKT3 | 1.32885083 |
| 34 | JAK1 | 1.29782439 |
| 35 | HCK | 1.27428206 |
| 36 | FGR | 1.24900604 |
| 37 | IKBKB | 1.22218799 |
| 38 | CAMK1G | 1.17370554 |
| 39 | SGK2 | 1.16730520 |
| 40 | YES1 | 1.16257230 |
| 41 | MARK3 | 1.13986748 |
| 42 | CDK12 | 1.13813817 |
| 43 | ACVR1B | 1.11578110 |
| 44 | JAK2 | 1.09351759 |
| 45 | MAP3K13 | 1.08000639 |
| 46 | MAP3K11 | 1.06178081 |
| 47 | CAMKK1 | 1.05776780 |
| 48 | MATK | 1.03971378 |
| 49 | LCK | 1.00918301 |
| 50 | GRK6 | 0.99678482 |
| 51 | CHUK | 0.97251620 |
| 52 | CAMKK2 | 0.96180642 |
| 53 | CLK1 | 0.94480432 |
| 54 | MAP3K1 | 0.92880561 |
| 55 | SGK3 | 0.92445643 |
| 56 | FGFR3 | 0.91991147 |
| 57 | IRAK3 | 0.87558352 |
| 58 | TRPM7 | 0.87142316 |
| 59 | CSF1R | 0.87141360 |
| 60 | TLK1 | 0.75475137 |
| 61 | MAPK7 | 0.75297226 |
| 62 | ABL1 | 0.74662293 |
| 63 | CDC42BPA | 0.74373314 |
| 64 | PRKAA2 | 0.70770439 |
| 65 | PIM1 | 0.70138068 |
| 66 | ERN1 | 0.69902350 |
| 67 | GRK7 | 0.69409797 |
| 68 | EPHB1 | 0.69046374 |
| 69 | MELK | 0.68044133 |
| 70 | SGK494 | 0.67158486 |
| 71 | SGK223 | 0.67158486 |
| 72 | MAP3K2 | 0.64505320 |
| 73 | CCNB1 | 0.61745698 |
| 74 | MAP3K5 | 0.60491921 |
| 75 | PTK2B | 0.58651634 |
| 76 | SGK1 | 0.55923960 |
| 77 | EPHA3 | 0.53970889 |
| 78 | CDK3 | 0.52826841 |
| 79 | PRPF4B | 0.51960253 |
| 80 | PRKCQ | 0.50892119 |
| 81 | EGFR | 0.50183306 |
| 82 | CDK6 | 0.49862204 |
| 83 | MAPKAPK2 | 0.49813691 |
| 84 | CAMK4 | 0.48785091 |
| 85 | IGF1R | 0.48747665 |
| 86 | MAP2K6 | 0.47220571 |
| 87 | PDK1 | 0.45313328 |
| 88 | MAP3K6 | 0.44839811 |
| 89 | HIPK2 | 0.41623681 |
| 90 | PIK3CA | 0.41100735 |
| 91 | STK4 | 0.40747934 |
| 92 | MARK2 | 0.38333352 |
| 93 | MAPK13 | 0.38003436 |
| 94 | PDPK1 | 0.37304504 |
| 95 | CDK19 | 0.36779533 |
| 96 | FYN | 0.36714917 |
| 97 | STK10 | 0.36636104 |
| 98 | NLK | 0.36104503 |
| 99 | ABL2 | 0.35723838 |
| 100 | FGFR4 | 0.31456574 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 3.66567342 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 3.35081213 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.28364322 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.15967619 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.12625687 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.09081505 |
| 7 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.97407870 |
| 8 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.75036858 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.44062462 |
| 10 | Tuberculosis_Homo sapiens_hsa05152 | 2.20239759 |
| 11 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.16963643 |
| 12 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.16453253 |
| 13 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.11528107 |
| 14 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.00496862 |
| 15 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.00360467 |
| 16 | Influenza A_Homo sapiens_hsa05164 | 1.98807652 |
| 17 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.98016440 |
| 18 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.95877378 |
| 19 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.74113604 |
| 20 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.73379710 |
| 21 | Viral myocarditis_Homo sapiens_hsa05416 | 1.73019861 |
| 22 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.66861463 |
| 23 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.65517459 |
| 24 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.62484282 |
| 25 | Measles_Homo sapiens_hsa05162 | 1.61734461 |
| 26 | Malaria_Homo sapiens_hsa05144 | 1.58503127 |
| 27 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.57973970 |
| 28 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.43900735 |
| 29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.43351407 |
| 30 | Hepatitis C_Homo sapiens_hsa05160 | 1.33853831 |
| 31 | Legionellosis_Homo sapiens_hsa05134 | 1.30221024 |
| 32 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.29385670 |
| 33 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.26556501 |
| 34 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.10383826 |
| 35 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.04915262 |
| 36 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.00229610 |
| 37 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.93304075 |
| 38 | Hepatitis B_Homo sapiens_hsa05161 | 0.92237164 |
| 39 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.89352505 |
| 40 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.89063371 |
| 41 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.88936008 |
| 42 | Platelet activation_Homo sapiens_hsa04611 | 0.88851826 |
| 43 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.84578737 |
| 44 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.84148574 |
| 45 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.82290229 |
| 46 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.81233766 |
| 47 | Phagosome_Homo sapiens_hsa04145 | 0.81216357 |
| 48 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.79216721 |
| 49 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.79033506 |
| 50 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.78170942 |
| 51 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.73642292 |
| 52 | Pertussis_Homo sapiens_hsa05133 | 0.71820306 |
| 53 | Other glycan degradation_Homo sapiens_hsa00511 | 0.68141962 |
| 54 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.64401960 |
| 55 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.63648809 |
| 56 | Shigellosis_Homo sapiens_hsa05131 | 0.61007882 |
| 57 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.59516188 |
| 58 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.55423648 |
| 59 | Insulin resistance_Homo sapiens_hsa04931 | 0.54510983 |
| 60 | ABC transporters_Homo sapiens_hsa02010 | 0.54495638 |
| 61 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.50090228 |
| 62 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.49161754 |
| 63 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.48763048 |
| 64 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.45526199 |
| 65 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.45120553 |
| 66 | RNA polymerase_Homo sapiens_hsa03020 | 0.43881906 |
| 67 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.42550145 |
| 68 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.40841263 |
| 69 | Taste transduction_Homo sapiens_hsa04742 | 0.38936969 |
| 70 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.38669726 |
| 71 | Lysine degradation_Homo sapiens_hsa00310 | 0.38341698 |
| 72 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.37778938 |
| 73 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.34733512 |
| 74 | Apoptosis_Homo sapiens_hsa04210 | 0.34373500 |
| 75 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.34065084 |
| 76 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.33096769 |
| 77 | Lysosome_Homo sapiens_hsa04142 | 0.32000193 |
| 78 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.31409005 |
| 79 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.29592340 |
| 80 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.29201304 |
| 81 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.28555210 |
| 82 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.27367047 |
| 83 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.26808148 |
| 84 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.25560386 |
| 85 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.23708270 |
| 86 | Salmonella infection_Homo sapiens_hsa05132 | 0.23349157 |
| 87 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.22521066 |
| 88 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.21886583 |
| 89 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.21763296 |
| 90 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.21433271 |
| 91 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.20694193 |
| 92 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.19950658 |
| 93 | Peroxisome_Homo sapiens_hsa04146 | 0.19932574 |
| 94 | RNA degradation_Homo sapiens_hsa03018 | 0.19930992 |
| 95 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.19637071 |
| 96 | HTLV-I infection_Homo sapiens_hsa05166 | 0.19628331 |
| 97 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.18846325 |
| 98 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.18667096 |
| 99 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.18162203 |
| 100 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.16843301 |

